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PMC:3317373 / 16892-18095 JSONTXT

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2_test

Id Subject Object Predicate Lexical cue
22529521-19430250-67992100 260-262 19430250 denotes 17
22529521-18162315-67992101 477-479 18162315 denotes 18
22529521-19515491-67992102 739-741 19515491 denotes 19

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T7731 637-638 -LRB- denotes (
T7730 620-636 JJ denotes 4-Hydroxynonenal
T7729 616-619 IN denotes for
T7728 599-615 NN denotes immunoreactivity
T7727 595-598 DT denotes the
T7726 585-594 VB denotes decreases
T7725 581-584 CC denotes and
T7724 577-580 NN denotes rat
T7723 574-576 IN denotes of
T7722 567-573 NN denotes memory
T7721 559-566 JJ denotes spatial
T7720 550-558 VB denotes improves
T7719 536-549 RB denotes significantly
T7718 534-535 -COMMA- denotes ,
T7717 530-534 NN denotes Nrf2
T7716 527-529 IN denotes of
T7715 519-526 NN denotes inducer
T7714 516-518 DT denotes an
T7713 514-515 -COMMA- denotes ,
T7712 511-514 NNP denotes SFN
T7711 508-510 IN denotes of
T7710 493-507 NN denotes administration
T7709 482-492 NN denotes Postinjury
T7708 479-480 -RRB- denotes ]
T7707 477-479 CD denotes 18
T7706 476-477 -LRB- denotes [
T7705 470-475 NN denotes brain
T7704 467-469 IN denotes in
T7703 460-466 NN denotes damage
T7702 456-459 DT denotes the
T7701 449-455 VB denotes reduce
T7700 436-448 RB denotes subsequently
T7699 430-435 MD denotes would
T7698 424-429 WDT denotes which
T7697 422-423 -COMMA- denotes ,
T7696 421-422 -RRB- denotes )
T7695 417-421 NN denotes NQO1
T7694 416-417 -LRB- denotes (
T7693 399-415 NN denotes oxidoreductase-1
T7692 391-398 NN denotes quinone
T7691 389-390 -COLON- denotes :
T7690 388-389 NN denotes H
T7689 387-388 -RRB- denotes )
T7688 386-387 NN denotes P
T7687 385-386 -LRB- denotes (
T7686 381-384 NN denotes NAD
T7685 377-380 CC denotes and
T7684 375-376 -RRB- denotes )
T7683 371-375 NN denotes HO-1
T7682 370-371 -LRB- denotes (
T7681 358-369 NN denotes oxygenase-1
T7680 353-357 NN denotes heme
T7679 350-352 IN denotes as
T7678 345-349 JJ denotes such
T7677 343-344 -COMMA- denotes ,
T7676 338-343 NN denotes genes
T7675 326-337 JJ denotes antioxidant
T7674 323-325 IN denotes of
T7673 317-322 NN denotes group
T7672 315-316 DT denotes a
T7671 312-314 IN denotes of
T7670 298-311 NN denotes transcription
T7669 288-297 VB denotes activates
T7668 283-287 NN denotes Nrf2
T7667 280-282 IN denotes of
T7666 274-279 NN denotes level
T7665 265-273 VB denotes Enhanced
T7664 262-263 -RRB- denotes ]
T7663 260-262 CD denotes 17
T7662 259-260 -LRB- denotes [
T7661 255-258 NNP denotes TBI
T7660 249-254 IN denotes after
T7659 242-248 NN denotes tissue
T7658 236-241 NN denotes brain
T7657 233-235 IN denotes in
T7656 228-232 NN denotes Nrf2
T7655 225-227 IN denotes of
T7654 212-224 NN denotes augmentation
T7653 208-211 DT denotes the
T7652 201-207 VB denotes proved
T7651 197-200 VB denotes has
T7650 191-196 NN denotes study
T7649 182-190 JJ denotes previous
T7648 178-181 PRP-DOLLAR- denotes Our
T7647 173-176 NNP denotes TBI
T7646 170-172 IN denotes in
T7645 161-169 VB denotes involved
T7644 157-160 DT denotes all
T7643 153-156 VB denotes are
T7642 147-152 WDT denotes which
T7641 145-146 -COMMA- denotes ,
T7640 134-145 NN denotes metabolites
T7639 128-133 JJ denotes toxic
T7638 125-127 IN denotes of
T7637 112-124 NN denotes accumulation
T7636 108-111 CC denotes and
T7635 106-107 -COMMA- denotes ,
T7634 100-106 NN denotes damage
T7633 87-99 JJ denotes inflammatory
T7632 85-86 -COMMA- denotes ,
T7631 79-85 NN denotes stress
T7630 69-78 JJ denotes oxidative
T7629 60-68 VB denotes reducing
T7628 57-59 IN denotes in
T7627 47-56 NN denotes regulator
T7626 43-46 JJ denotes key
T7625 39-42 DT denotes the
T7624 36-38 VB denotes be
T7623 33-35 TO denotes to
T7622 26-32 VB denotes proved
T7621 21-25 VB denotes been
T7620 17-20 VB denotes has
T7619 9-16 NN denotes pathway
T7618 0-8 NN denotes Nrf2-ARE
T7829 1196-1202 NN denotes deaths
T7828 1185-1195 NN denotes astrocytes
T7827 1180-1184 JJ denotes more
T7826 1177-1179 TO denotes to
T7825 1173-1176 VB denotes led
T7824 1163-1172 NN denotes mediators
T7823 1147-1162 JJ denotes proinflammatory
T7822 1141-1146 DT denotes these
T7821 1138-1140 IN denotes of
T7820 1123-1137 NN denotes overexpression
T7819 1119-1122 CC denotes and
T7818 1117-1118 -COMMA- denotes ,
T7817 1113-1117 NN denotes time
T7816 1107-1112 JJ denotes first
T7815 1103-1106 DT denotes the
T7814 1099-1102 IN denotes for
T7813 1087-1098 NN denotes astrocyetes
T7812 1078-1086 JJ denotes wildtype
T7811 1075-1077 IN denotes in
T7810 1070-1074 IN denotes than
T7809 1059-1069 NN denotes astrocytes
T7808 1050-1058 NN denotes knockout
T7807 1045-1049 NN denotes Nrf2
T7806 1036-1044 VB denotes cultured
T7805 1033-1035 IN denotes in
T7804 1022-1032 VB denotes aggravated
T7803 1017-1021 RB denotes more
T7802 1013-1016 VB denotes was
T7801 1006-1012 NN denotes injury
T7800 998-1005 NN denotes scratch
T7799 992-997 IN denotes after
T7798 987-991 NN denotes MMP9
T7797 983-986 CC denotes and
T7796 981-982 -COMMA- denotes ,
T7795 977-981 NN denotes IL-6
T7794 975-976 -COMMA- denotes ,
T7793 970-975 NN denotes IL-1β
T7792 968-969 -COMMA- denotes ,
T7791 963-968 NN denotes TNF-α
T7790 960-962 IN denotes of
T7789 945-959 NN denotes overexpression
T7788 940-944 IN denotes that
T7787 931-939 VB denotes revealed
T7786 923-930 NN denotes results
T7785 919-922 PRP-DOLLAR- denotes our
T7784 917-918 -COMMA- denotes ,
T7783 913-917 RB denotes Here
T7782 910-911 -RRB- denotes ]
T7781 908-910 CD denotes 20
T7780 907-908 -LRB- denotes [
T7779 903-906 NNP denotes TBI
T7778 897-902 IN denotes after
T7777 891-896 NN denotes brain
T7776 888-890 IN denotes in
T7775 878-887 NN denotes mediators
T7774 862-877 JJ denotes proinflammatory
T7773 859-861 IN denotes of
T7772 848-858 NN denotes expression
T7771 841-847 JJ denotes higher
T7770 833-840 VB denotes induces
T7769 828-832 NN denotes Nrf2
T7768 825-827 IN denotes of
T7767 815-824 NN denotes Depletion
T7766 810-813 NNP denotes TBI
T7765 807-809 TO denotes to
T7764 795-806 JJ denotes susceptible
T7763 790-794 RB denotes more
T7762 783-789 VB denotes appear
T7761 778-782 NN denotes mice
T7760 763-777 JJ denotes Nrf2-deficient
T7759 761-762 -COMMA- denotes ,
T7758 757-761 NN denotes hand
T7757 751-756 JJ denotes other
T7756 747-750 DT denotes the
T7755 744-746 IN denotes On
T7754 741-742 -RRB- denotes ]
T7753 739-741 CD denotes 19
T7752 738-739 -LRB- denotes [
T7751 734-737 NNP denotes TBI
T7750 728-733 IN denotes after
T7749 716-727 NN denotes hippocampus
T7748 713-715 IN denotes of
T7747 704-712 NN denotes subfield
T7746 700-703 NN denotes CA3
T7745 696-699 DT denotes the
T7744 692-695 CC denotes and
T7743 685-691 NN denotes cortex
T7742 681-684 DT denotes the
T7741 678-680 IN denotes in
T7740 676-677 -COMMA- denotes ,
T7739 664-676 NN denotes peroxidation
T7738 658-663 NN denotes lipid
T7737 655-657 IN denotes of
T7736 648-654 NN denotes marker
T7735 646-647 DT denotes a
T7734 644-645 -COMMA- denotes ,
T7733 643-644 -RRB- denotes )
T7732 638-643 NN denotes 4-HNE
R6159 T7619 T7618 arg1Of pathway,Nrf2-ARE
R6160 T7619 T7620 arg1Of pathway,has
R6161 T7619 T7621 arg1Of pathway,been
R6162 T7619 T7622 arg2Of pathway,proved
R6163 T7619 T7624 arg1Of pathway,be
R6164 T7622 T7620 arg2Of proved,has
R6165 T7622 T7621 arg2Of proved,been
R6166 T7624 T7622 arg3Of be,proved
R6167 T7624 T7623 arg1Of be,to
R6168 T7627 T7624 arg2Of regulator,be
R6169 T7627 T7625 arg1Of regulator,the
R6170 T7627 T7626 arg1Of regulator,key
R6171 T7627 T7628 arg1Of regulator,in
R6172 T7629 T7628 arg2Of reducing,in
R6173 T7631 T7630 arg1Of stress,oxidative
R6174 T7631 T7632 arg1Of stress,","
R6175 T7632 T7636 arg1Of ",",and
R6176 T7634 T7632 arg2Of damage,","
R6177 T7634 T7633 arg1Of damage,inflammatory
R6178 T7636 T7629 arg2Of and,reducing
R6179 T7636 T7635 arg1Of and,","
R6180 T7637 T7636 arg2Of accumulation,and
R6181 T7637 T7638 arg1Of accumulation,of
R6182 T7640 T7638 arg2Of metabolites,of
R6183 T7640 T7639 arg1Of metabolites,toxic
R6184 T7640 T7641 arg1Of metabolites,","
R6185 T7640 T7642 arg1Of metabolites,which
R6186 T7640 T7643 arg1Of metabolites,are
R6187 T7640 T7645 arg2Of metabolites,involved
R6188 T7645 T7643 arg2Of involved,are
R6189 T7645 T7644 arg1Of involved,all
R6190 T7645 T7646 arg1Of involved,in
R6191 T7647 T7646 arg2Of TBI,in
R6192 T7650 T7648 arg1Of study,Our
R6193 T7650 T7649 arg1Of study,previous
R6194 T7650 T7651 arg1Of study,has
R6195 T7650 T7652 arg1Of study,proved
R6196 T7652 T7651 arg2Of proved,has
R6197 T7652 T7660 arg1Of proved,after
R6198 T7654 T7652 arg2Of augmentation,proved
R6199 T7654 T7653 arg1Of augmentation,the
R6200 T7654 T7655 arg1Of augmentation,of
R6201 T7654 T7657 arg1Of augmentation,in
R6202 T7656 T7655 arg2Of Nrf2,of
R6203 T7659 T7657 arg2Of tissue,in
R6204 T7659 T7658 arg1Of tissue,brain
R6205 T7661 T7660 arg2Of TBI,after
R6206 T7661 T7662 arg1Of TBI,[
R6207 T7663 T7662 arg2Of 17,[
R6208 T7664 T7662 arg3Of ],[
R6209 T7666 T7665 arg2Of level,Enhanced
R6210 T7666 T7667 arg1Of level,of
R6211 T7666 T7669 arg1Of level,activates
R6212 T7668 T7667 arg2Of Nrf2,of
R6213 T7670 T7669 arg2Of transcription,activates
R6214 T7670 T7671 arg1Of transcription,of
R6215 T7670 T7677 arg1Of transcription,","
R6216 T7670 T7679 arg1Of transcription,as
R6217 T7673 T7671 arg2Of group,of
R6218 T7673 T7672 arg1Of group,a
R6219 T7673 T7674 arg1Of group,of
R6220 T7676 T7674 arg2Of genes,of
R6221 T7676 T7675 arg1Of genes,antioxidant
R6222 T7679 T7678 arg1Of as,such
R6223 T7681 T7680 arg1Of oxygenase-1,heme
R6224 T7681 T7682 arg1Of oxygenase-1,(
R6225 T7681 T7685 arg1Of oxygenase-1,and
R6226 T7683 T7682 arg2Of HO-1,(
R6227 T7684 T7682 arg3Of ),(
R6228 T7685 T7679 arg2Of and,as
R6229 T7685 T7691 arg1Of and,:
R6230 T7688 T7687 arg2Of P,(
R6231 T7689 T7687 arg3Of ),(
R6232 T7690 T7685 arg2Of H,and
R6233 T7690 T7686 arg1Of H,NAD
R6234 T7690 T7687 arg1Of H,(
R6235 T7693 T7691 arg2Of oxidoreductase-1,:
R6236 T7693 T7692 arg1Of oxidoreductase-1,quinone
R6237 T7693 T7694 arg1Of oxidoreductase-1,(
R6238 T7693 T7697 arg1Of oxidoreductase-1,","
R6239 T7693 T7698 arg1Of oxidoreductase-1,which
R6240 T7693 T7699 arg1Of oxidoreductase-1,would
R6241 T7693 T7701 arg1Of oxidoreductase-1,reduce
R6242 T7695 T7694 arg2Of NQO1,(
R6243 T7696 T7694 arg3Of ),(
R6244 T7701 T7699 arg2Of reduce,would
R6245 T7701 T7700 arg1Of reduce,subsequently
R6246 T7703 T7701 arg2Of damage,reduce
R6247 T7703 T7702 arg1Of damage,the
R6248 T7703 T7704 arg1Of damage,in
R6249 T7705 T7704 arg2Of brain,in
R6250 T7705 T7706 arg1Of brain,[
R6251 T7707 T7706 arg2Of 18,[
R6252 T7708 T7706 arg3Of ],[
R6253 T7710 T7709 arg1Of administration,Postinjury
R6254 T7710 T7711 arg1Of administration,of
R6255 T7710 T7720 arg1Of administration,improves
R6256 T7710 T7726 arg1Of administration,decreases
R6257 T7712 T7711 arg2Of SFN,of
R6258 T7712 T7713 arg1Of SFN,","
R6259 T7715 T7713 arg2Of inducer,","
R6260 T7715 T7714 arg1Of inducer,an
R6261 T7715 T7716 arg1Of inducer,of
R6262 T7717 T7716 arg2Of Nrf2,of
R6263 T7720 T7725 arg1Of improves,and
R6264 T7722 T7720 arg2Of memory,improves
R6265 T7722 T7721 arg1Of memory,spatial
R6266 T7722 T7723 arg1Of memory,of
R6267 T7724 T7723 arg2Of rat,of
R6268 T7725 T7718 arg1Of and,","
R6269 T7725 T7719 arg1Of and,significantly
R6270 T7726 T7725 arg2Of decreases,and
R6271 T7728 T7726 arg2Of immunoreactivity,decreases
R6272 T7728 T7727 arg1Of immunoreactivity,the
R6273 T7728 T7729 arg1Of immunoreactivity,for
R6274 T7728 T7740 arg1Of immunoreactivity,","
R6275 T7728 T7741 arg1Of immunoreactivity,in
R6276 T7730 T7729 arg2Of 4-Hydroxynonenal,for
R6277 T7730 T7731 arg1Of 4-Hydroxynonenal,(
R6278 T7730 T7734 arg1Of 4-Hydroxynonenal,","
R6279 T7732 T7731 arg2Of 4-HNE,(
R6280 T7733 T7731 arg3Of ),(
R6281 T7736 T7734 arg2Of marker,","
R6282 T7736 T7735 arg1Of marker,a
R6283 T7736 T7737 arg1Of marker,of
R6284 T7739 T7737 arg2Of peroxidation,of
R6285 T7739 T7738 arg1Of peroxidation,lipid
R6286 T7743 T7742 arg1Of cortex,the
R6287 T7743 T7744 arg1Of cortex,and
R6288 T7744 T7741 arg2Of and,in
R6289 T7747 T7744 arg2Of subfield,and
R6290 T7747 T7745 arg1Of subfield,the
R6291 T7747 T7746 arg1Of subfield,CA3
R6292 T7747 T7748 arg1Of subfield,of
R6293 T7747 T7750 arg1Of subfield,after
R6294 T7749 T7748 arg2Of hippocampus,of
R6295 T7751 T7750 arg2Of TBI,after
R6296 T7751 T7752 arg1Of TBI,[
R6297 T7753 T7752 arg2Of 19,[
R6298 T7754 T7752 arg3Of ],[
R6299 T7758 T7755 arg2Of hand,On
R6300 T7758 T7756 arg1Of hand,the
R6301 T7758 T7757 arg1Of hand,other
R6302 T7761 T7760 arg1Of mice,Nrf2-deficient
R6303 T7761 T7762 arg1Of mice,appear
R6304 T7761 T7764 arg1Of mice,susceptible
R6305 T7762 T7755 arg1Of appear,On
R6306 T7762 T7759 arg1Of appear,","
R6307 T7764 T7762 arg2Of susceptible,appear
R6308 T7764 T7763 arg1Of susceptible,more
R6309 T7764 T7765 arg1Of susceptible,to
R6310 T7766 T7765 arg2Of TBI,to
R6311 T7767 T7768 arg1Of Depletion,of
R6312 T7767 T7770 arg1Of Depletion,induces
R6313 T7769 T7768 arg2Of Nrf2,of
R6314 T7770 T7776 arg1Of induces,in
R6315 T7772 T7770 arg2Of expression,induces
R6316 T7772 T7771 arg1Of expression,higher
R6317 T7772 T7773 arg1Of expression,of
R6318 T7775 T7773 arg2Of mediators,of
R6319 T7775 T7774 arg1Of mediators,proinflammatory
R6320 T7777 T7776 arg2Of brain,in
R6321 T7777 T7778 arg1Of brain,after
R6322 T7779 T7778 arg2Of TBI,after
R6323 T7779 T7780 arg1Of TBI,[
R6324 T7781 T7780 arg2Of 20,[
R6325 T7782 T7780 arg3Of ],[
R6326 T7786 T7785 arg1Of results,our
R6327 T7786 T7787 arg1Of results,revealed
R6328 T7787 T7783 arg1Of revealed,Here
R6329 T7787 T7784 arg1Of revealed,","
R6330 T7789 T7790 arg1Of overexpression,of
R6331 T7789 T7802 arg1Of overexpression,was
R6332 T7789 T7804 arg2Of overexpression,aggravated
R6333 T7791 T7792 arg1Of TNF-α,","
R6334 T7792 T7794 arg1Of ",",","
R6335 T7793 T7792 arg2Of IL-1β,","
R6336 T7794 T7797 arg1Of ",",and
R6337 T7795 T7794 arg2Of IL-6,","
R6338 T7797 T7790 arg2Of and,of
R6339 T7797 T7796 arg1Of and,","
R6340 T7797 T7799 arg1Of and,after
R6341 T7798 T7797 arg2Of MMP9,and
R6342 T7801 T7799 arg2Of injury,after
R6343 T7801 T7800 arg1Of injury,scratch
R6344 T7804 T7802 arg2Of aggravated,was
R6345 T7804 T7803 arg1Of aggravated,more
R6346 T7804 T7805 arg1Of aggravated,in
R6347 T7804 T7810 arg1Of aggravated,than
R6348 T7804 T7814 arg1Of aggravated,for
R6349 T7804 T7819 arg1Of aggravated,and
R6350 T7809 T7805 arg2Of astrocytes,in
R6351 T7809 T7806 arg2Of astrocytes,cultured
R6352 T7809 T7807 arg1Of astrocytes,Nrf2
R6353 T7809 T7808 arg1Of astrocytes,knockout
R6354 T7811 T7810 arg2Of in,than
R6355 T7813 T7811 arg2Of astrocyetes,in
R6356 T7813 T7812 arg1Of astrocyetes,wildtype
R6357 T7817 T7814 arg2Of time,for
R6358 T7817 T7815 arg1Of time,the
R6359 T7817 T7816 arg1Of time,first
R6360 T7819 T7787 arg2Of and,revealed
R6361 T7819 T7788 arg1Of and,that
R6362 T7819 T7818 arg1Of and,","
R6363 T7820 T7821 arg1Of overexpression,of
R6364 T7820 T7825 arg1Of overexpression,led
R6365 T7824 T7821 arg2Of mediators,of
R6366 T7824 T7822 arg1Of mediators,these
R6367 T7824 T7823 arg1Of mediators,proinflammatory
R6368 T7825 T7819 arg2Of led,and
R6369 T7825 T7826 arg1Of led,to
R6370 T7829 T7826 arg2Of deaths,to
R6371 T7829 T7827 arg1Of deaths,more
R6372 T7829 T7828 arg1Of deaths,astrocytes

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T7330 987-991 Protein denotes MMP9
T7329 977-981 Protein denotes IL-6
T7328 970-975 Protein denotes IL-1β
T7327 371-375 Protein denotes HO-1
T7326 353-369 Protein denotes heme oxygenase-1

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T8383 977-981 http://www.uniprot.org/uniprot/P05231 denotes IL-6
T8368 963-968 http://www.uniprot.org/uniprot/P01375 denotes TNF-α
T8361 963-966 http://www.uniprot.org/uniprot/P01375 denotes TNF
T8376 970-975 http://www.uniprot.org/uniprot/P01584 denotes IL-1β

UBERON-AE

Id Subject Object Predicate Lexical cue
T7207 685-691 http://purl.obolibrary.org/obo/UBERON_0001851 denotes cortex
T7205 242-248 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue
T7199 891-896 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T7198 470-475 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T7197 236-241 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain

GO-BP

Id Subject Object Predicate Lexical cue
T7354 1196-1202 http://purl.obolibrary.org/obo/GO_0016265 denotes deaths
T7353 567-573 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T7352 417-421 http://purl.obolibrary.org/obo/GO_0003955 denotes NQO1
T7351 358-367 http://purl.obolibrary.org/obo/GO_0016701 denotes oxygenase
T7347 298-311 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription

GO-MF

Id Subject Object Predicate Lexical cue
T8285 977-981 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T8292 417-421 http://purl.obolibrary.org/obo/GO_0003955 denotes NQO1
T8291 358-367 http://purl.obolibrary.org/obo/GO_0016701 denotes oxygenase

sentences

Id Subject Object Predicate Lexical cue
T7229 913-1203 Sentence denotes Here, our results revealed that overexpression of TNF-α, IL-1β, IL-6, and MMP9 after scratch injury was more aggravated in cultured Nrf2 knockout astrocytes than in wildtype astrocyetes for the first time, and overexpression of these proinflammatory mediators led to more astrocytes deaths.
T7228 815-912 Sentence denotes Depletion of Nrf2 induces higher expression of proinflammatory mediators in brain after TBI [20].
T7227 744-814 Sentence denotes On the other hand, Nrf2-deficient mice appear more susceptible to TBI.
T7226 482-743 Sentence denotes Postinjury administration of SFN, an inducer of Nrf2, significantly improves spatial memory of rat and decreases the immunoreactivity for 4-Hydroxynonenal (4-HNE), a marker of lipid peroxidation, in the cortex and the CA3 subfield of hippocampus after TBI [19].
T7225 265-481 Sentence denotes Enhanced level of Nrf2 activates transcription of a group of antioxidant genes, such as heme oxygenase-1 (HO-1) and NAD (P)H: quinone oxidoreductase-1 (NQO1), which would subsequently reduce the damage in brain [18].
T7224 178-264 Sentence denotes Our previous study has proved the augmentation of Nrf2 in brain tissue after TBI [17].
T7223 0-177 Sentence denotes Nrf2-ARE pathway has been proved to be the key regulator in reducing oxidative stress, inflammatory damage, and accumulation of toxic metabolites, which are all involved in TBI.
T169 0-177 Sentence denotes Nrf2-ARE pathway has been proved to be the key regulator in reducing oxidative stress, inflammatory damage, and accumulation of toxic metabolites, which are all involved in TBI.
T170 178-264 Sentence denotes Our previous study has proved the augmentation of Nrf2 in brain tissue after TBI [17].
T171 265-481 Sentence denotes Enhanced level of Nrf2 activates transcription of a group of antioxidant genes, such as heme oxygenase-1 (HO-1) and NAD (P)H: quinone oxidoreductase-1 (NQO1), which would subsequently reduce the damage in brain [18].
T172 482-743 Sentence denotes Postinjury administration of SFN, an inducer of Nrf2, significantly improves spatial memory of rat and decreases the immunoreactivity for 4-Hydroxynonenal (4-HNE), a marker of lipid peroxidation, in the cortex and the CA3 subfield of hippocampus after TBI [19].
T173 744-814 Sentence denotes On the other hand, Nrf2-deficient mice appear more susceptible to TBI.
T174 815-912 Sentence denotes Depletion of Nrf2 induces higher expression of proinflammatory mediators in brain after TBI [20].
T175 913-1203 Sentence denotes Here, our results revealed that overexpression of TNF-α, IL-1β, IL-6, and MMP9 after scratch injury was more aggravated in cultured Nrf2 knockout astrocytes than in wildtype astrocyetes for the first time, and overexpression of these proinflammatory mediators led to more astrocytes deaths.

ICD10

Id Subject Object Predicate Lexical cue
T8273 1006-1012 http://purl.bioontology.org/ontology/ICD10/T14.9 denotes injury

simple1

Id Subject Object Predicate Lexical cue
T8345 987-991 Protein denotes MMP9
T8344 977-981 Protein denotes IL-6
T8343 970-975 Protein denotes IL-1β
T8342 371-375 Protein denotes HO-1
T8341 353-369 Protein denotes heme oxygenase-1

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T9928 1022-1032 Positive_regulation denotes aggravated
T9927 945-959 Positive_regulation denotes overexpression
T9926 298-311 Transcription denotes transcription
T9925 288-297 Positive_regulation denotes activates
T9904 987-991 Protein denotes MMP9
T9903 977-981 Protein denotes IL-6
T9902 970-975 Protein denotes IL-1β
T9901 371-375 Protein denotes HO-1
T9900 353-369 Protein denotes heme oxygenase-1
R8145 T9902 T9927 themeOf IL-1β,overexpression
R8147 T9903 T9927 themeOf IL-6,overexpression
R8148 T9904 T9927 themeOf MMP9,overexpression
R8160 T9900 T9926 themeOf heme oxygenase-1,transcription
R8162 T9901 T9926 themeOf HO-1,transcription
R8183 T9926 T9925 themeOf transcription,activates
R8185 T9926 T9925 themeOf transcription,activates
R8186 T9927 T9928 themeOf overexpression,aggravated
R8190 T9927 T9928 themeOf overexpression,aggravated
R8191 T9927 T9928 themeOf overexpression,aggravated

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T8483 1022-1032 Positive_regulation denotes aggravated
T8482 945-959 Positive_regulation denotes overexpression
T8481 288-297 Positive_regulation denotes activates
T8480 298-311 Transcription denotes transcription
T8460 987-991 Protein denotes MMP9
T8459 977-981 Protein denotes IL-6
T8458 970-975 Protein denotes IL-1β
T8457 371-375 Protein denotes HO-1
T8456 353-369 Protein denotes heme oxygenase-1
R6876 T8456 T8480 themeOf heme oxygenase-1,transcription
R6877 T8457 T8480 themeOf HO-1,transcription
R6878 T8458 T8483 themeOf IL-1β,aggravated
R6879 T8458 T8482 themeOf IL-1β,overexpression
R6880 T8459 T8482 themeOf IL-6,overexpression
R6881 T8460 T8483 themeOf MMP9,aggravated
R6882 T8460 T8482 themeOf MMP9,overexpression
R6900 T8480 T8481 themeOf transcription,activates
R6901 T8480 T8481 themeOf transcription,activates
R6902 T8482 T8483 themeOf overexpression,aggravated
R6903 T8482 T8483 themeOf overexpression,aggravated
R6904 T8482 T8483 themeOf overexpression,aggravated

DLUT931

Id Subject Object Predicate Lexical cue
T8433 1022-1032 Positive_regulation denotes aggravated
T8432 945-959 Positive_regulation denotes overexpression
T8431 288-297 Positive_regulation denotes activates
T8430 298-311 Transcription denotes transcription
T8409 987-991 Protein denotes MMP9
T8408 977-981 Protein denotes IL-6
T8407 970-975 Protein denotes IL-1β
T8406 371-375 Protein denotes HO-1
T8405 353-369 Protein denotes heme oxygenase-1
R6855 T8430 T8431 themeOf transcription,activates
R6856 T8430 T8431 themeOf transcription,activates
R6857 T8432 T8433 themeOf overexpression,aggravated
R6826 T8405 T8430 themeOf heme oxygenase-1,transcription
R6827 T8406 T8430 themeOf HO-1,transcription
R6828 T8407 T8432 themeOf IL-1β,overexpression
R6829 T8408 T8432 themeOf IL-6,overexpression
R6830 T8409 T8432 themeOf MMP9,overexpression
R6858 T8432 T8433 themeOf overexpression,aggravated
R6859 T8432 T8433 themeOf overexpression,aggravated

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T10084 940-1005 Gene_expression denotes that overexpression of TNF-α, IL-1β, IL-6, and MMP9 after scratch
T10083 940-1005 Positive_regulation denotes that overexpression of TNF-α, IL-1β, IL-6, and MMP9 after scratch
T10082 940-1005 Gene_expression denotes that overexpression of TNF-α, IL-1β, IL-6, and MMP9 after scratch
T10081 940-1005 Positive_regulation denotes that overexpression of TNF-α, IL-1β, IL-6, and MMP9 after scratch
T10080 940-1005 Gene_expression denotes that overexpression of TNF-α, IL-1β, IL-6, and MMP9 after scratch
T10079 940-1005 Gene_expression denotes that overexpression of TNF-α, IL-1β, IL-6, and MMP9 after scratch
T10078 940-1005 Positive_regulation denotes that overexpression of TNF-α, IL-1β, IL-6, and MMP9 after scratch
T10077 940-1005 Positive_regulation denotes that overexpression of TNF-α, IL-1β, IL-6, and MMP9 after scratch
T10039 825-832 Protein denotes of Nrf2
T10031 970-975 Protein denotes IL-1β
T10030 225-248 Protein denotes of Nrf2 in brain tissue
T10024 987-1005 Protein denotes MMP9 after scratch
T10021 371-375 Protein denotes HO-1
T10020 125-145 Entity denotes of toxic metabolites
T10016 353-423 Entity denotes heme oxygenase-1 (HO-1) and NAD (P)H: quinone oxidoreductase-1 (NQO1),
T10007 977-981 Protein denotes IL-6
T10005 511-515 Protein denotes SFN,
T10000 763-782 Protein denotes Nrf2-deficient mice
T9995 326-337 Entity denotes antioxidant
T9992 700-703 Protein denotes CA3
T9988 391-413 Protein denotes quinone oxidoreductase
T9980 1050-1069 Entity denotes knockout astrocytes
T9971 1177-1202 Entity denotes to more astrocytes deaths
T9968 326-344 Protein denotes antioxidant genes,
T9955 386-387 Entity denotes P
T9946 963-968 Protein denotes TNF-α
T10065 225-249 Localization denotes of Nrf2 in brain tissue
T10058 112-145 Binding denotes accumulation of toxic metabolites
T10052 417-421 Protein denotes NQO1
T10049 381-388 Entity denotes NAD (P)
T10044 658-663 Entity denotes lipid
T10040 353-376 Protein denotes heme oxygenase-1 (HO-1)
R8178 T9946 T10077 themeOf TNF-α,"that overexpression of TNF-α, IL-1β, IL-6, and MMP9 after scratch"
R8179 T9946 T10084 themeOf TNF-α,"that overexpression of TNF-α, IL-1β, IL-6, and MMP9 after scratch"
R8215 T10024 T10079 themeOf MMP9 after scratch,"that overexpression of TNF-α, IL-1β, IL-6, and MMP9 after scratch"
R8217 T10024 T10081 themeOf MMP9 after scratch,"that overexpression of TNF-α, IL-1β, IL-6, and MMP9 after scratch"
R8221 T10007 T10078 themeOf IL-6,"that overexpression of TNF-α, IL-1β, IL-6, and MMP9 after scratch"
R8222 T10007 T10082 themeOf IL-6,"that overexpression of TNF-α, IL-1β, IL-6, and MMP9 after scratch"
R8228 T10030 T10065 themeOf of Nrf2 in brain tissue,of Nrf2 in brain tissue
R8229 T10031 T10080 themeOf IL-1β,"that overexpression of TNF-α, IL-1β, IL-6, and MMP9 after scratch"
R8230 T10031 T10083 themeOf IL-1β,"that overexpression of TNF-α, IL-1β, IL-6, and MMP9 after scratch"

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T9114 595-598 DT denotes the
T9113 585-594 VBZ denotes decreases
T9112 581-584 CC denotes and
T9111 577-580 NN denotes rat
T9110 574-576 IN denotes of
T9109 567-573 NN denotes memory
T9108 559-566 JJ denotes spatial
T9107 550-558 VBZ denotes improves
T9106 536-549 RB denotes significantly
T9105 534-535 , denotes ,
T9104 530-534 NNP denotes Nrf2
T9103 527-529 IN denotes of
T9102 519-526 NN denotes inducer
T9101 516-518 DT denotes an
T9100 514-515 , denotes ,
T9099 511-514 NNP denotes SFN
T9098 508-510 IN denotes of
T9097 493-507 NN denotes administration
T9096 482-492 NNP denotes Postinjury
T9095 480-481 . denotes .
T9094 479-480 NNP denotes ]
T9093 477-479 CD denotes 18
T9092 476-477 NNP denotes [
T9091 470-475 NN denotes brain
T9090 467-469 IN denotes in
T9089 460-466 NN denotes damage
T9088 456-459 DT denotes the
T9087 449-455 VB denotes reduce
T9086 436-448 RB denotes subsequently
T9085 430-435 MD denotes would
T9084 424-429 WDT denotes which
T9083 422-423 , denotes ,
T9082 421-422 -RRB- denotes )
T9081 417-421 CD denotes NQO1
T9080 416-417 -LRB- denotes (
T9079 399-415 JJ denotes oxidoreductase-1
T9078 391-398 VB denotes quinone
T9077 389-390 : denotes :
T9076 388-389 NNP denotes H
T9075 387-388 -RRB- denotes )
T9074 386-387 NNP denotes P
T9073 385-386 -LRB- denotes (
T9072 381-384 NNP denotes NAD
T9071 377-380 CC denotes and
T9070 375-376 -RRB- denotes )
T9069 371-375 JJ denotes HO-1
T9068 370-371 -LRB- denotes (
T9067 358-369 JJ denotes oxygenase-1
T9066 353-357 NN denotes heme
T9065 350-352 IN denotes as
T9064 345-349 JJ denotes such
T9063 343-344 , denotes ,
T9062 338-343 NNS denotes genes
T9061 326-337 JJ denotes antioxidant
T9060 323-325 IN denotes of
T9059 317-322 NN denotes group
T9058 315-316 DT denotes a
T9057 312-314 IN denotes of
T9056 298-311 NN denotes transcription
T9055 288-297 NNS denotes activates
T9054 283-287 JJ denotes Nrf2
T9053 280-282 IN denotes of
T9052 274-279 NN denotes level
T9051 265-273 JJ denotes Enhanced
T9050 263-264 . denotes .
T9049 262-263 NNP denotes ]
T9048 260-262 CD denotes 17
T9047 259-260 NNP denotes [
T9046 255-258 NNP denotes TBI
T9045 249-254 IN denotes after
T9044 242-248 NN denotes tissue
T9043 236-241 NN denotes brain
T9042 233-235 IN denotes in
T9041 228-232 NNP denotes Nrf2
T9040 225-227 IN denotes of
T9039 212-224 NN denotes augmentation
T9038 208-211 DT denotes the
T9037 201-207 VBN denotes proved
T9036 197-200 VBZ denotes has
T9035 191-196 NN denotes study
T9034 182-190 JJ denotes previous
T9033 178-181 PRP$ denotes Our
T9032 176-177 . denotes .
T9031 173-176 NNP denotes TBI
T9030 170-172 IN denotes in
T9029 161-169 VBN denotes involved
T9028 157-160 DT denotes all
T9027 153-156 VBP denotes are
T9026 147-152 WDT denotes which
T9025 145-146 , denotes ,
T9024 134-145 NNS denotes metabolites
T9023 128-133 JJ denotes toxic
T9022 125-127 IN denotes of
T9021 112-124 NN denotes accumulation
T9020 108-111 CC denotes and
T9019 106-107 , denotes ,
T9018 100-106 NN denotes damage
T9017 87-99 JJ denotes inflammatory
T9016 85-86 , denotes ,
T9015 79-85 NN denotes stress
T9014 69-78 JJ denotes oxidative
T9013 60-68 VBG denotes reducing
T9012 57-59 IN denotes in
T9011 47-56 NN denotes regulator
T9010 43-46 JJ denotes key
T9009 39-42 DT denotes the
T9008 36-38 VB denotes be
T9007 33-35 TO denotes to
T9006 26-32 VBN denotes proved
T9005 21-25 VBN denotes been
T9004 17-20 VBZ denotes has
T9003 9-16 NN denotes pathway
T9002 0-8 JJ denotes Nrf2-ARE
T9220 1202-1203 . denotes .
T9219 1196-1202 NNS denotes deaths
T9218 1185-1195 NNS denotes astrocytes
T9217 1180-1184 JJR denotes more
T9216 1177-1179 TO denotes to
T9215 1173-1176 VBD denotes led
T9214 1163-1172 NNS denotes mediators
T9213 1147-1162 JJ denotes proinflammatory
T9212 1141-1146 DT denotes these
T9211 1138-1140 IN denotes of
T9210 1123-1137 NN denotes overexpression
T9209 1119-1122 CC denotes and
T9208 1117-1118 , denotes ,
T9207 1113-1117 NN denotes time
T9206 1107-1112 JJ denotes first
T9205 1103-1106 DT denotes the
T9204 1099-1102 IN denotes for
T9203 1087-1098 NNS denotes astrocyetes
T9202 1078-1086 NN denotes wildtype
T9201 1075-1077 IN denotes in
T9200 1070-1074 IN denotes than
T9199 1059-1069 NNS denotes astrocytes
T9198 1050-1058 NN denotes knockout
T9197 1045-1049 JJ denotes Nrf2
T9196 1036-1044 JJ denotes cultured
T9195 1033-1035 IN denotes in
T9194 1022-1032 VBN denotes aggravated
T9193 1017-1021 RBR denotes more
T9192 1013-1016 VBD denotes was
T9191 1006-1012 NN denotes injury
T9190 998-1005 NN denotes scratch
T9189 992-997 IN denotes after
T9188 987-991 NNP denotes MMP9
T9187 983-986 CC denotes and
T9186 981-982 , denotes ,
T9185 977-981 NNP denotes IL-6
T9184 975-976 , denotes ,
T9183 970-975 NNP denotes IL-1β
T9182 968-969 , denotes ,
T9181 963-968 NNP denotes TNF-α
T9180 960-962 IN denotes of
T9179 945-959 NN denotes overexpression
T9178 940-944 IN denotes that
T9177 931-939 VBD denotes revealed
T9176 923-930 NNS denotes results
T9175 919-922 PRP$ denotes our
T9174 917-918 , denotes ,
T9173 913-917 RB denotes Here
T9172 911-912 . denotes .
T9171 910-911 NNP denotes ]
T9170 908-910 CD denotes 20
T9169 907-908 NNP denotes [
T9168 903-906 NNP denotes TBI
T9167 897-902 IN denotes after
T9166 891-896 NN denotes brain
T9165 888-890 IN denotes in
T9164 878-887 NNS denotes mediators
T9163 862-877 JJ denotes proinflammatory
T9162 859-861 IN denotes of
T9161 848-858 NN denotes expression
T9160 841-847 JJR denotes higher
T9159 833-840 VBZ denotes induces
T9158 828-832 JJ denotes Nrf2
T9157 825-827 IN denotes of
T9156 815-824 NN denotes Depletion
T9155 813-814 . denotes .
T9154 810-813 NNP denotes TBI
T9153 807-809 TO denotes to
T9152 795-806 JJ denotes susceptible
T9151 790-794 JJR denotes more
T9150 783-789 VBP denotes appear
T9149 778-782 NNS denotes mice
T9148 763-777 JJ denotes Nrf2-deficient
T9147 761-762 , denotes ,
T9146 757-761 NN denotes hand
T9145 751-756 JJ denotes other
T9144 747-750 DT denotes the
T9143 744-746 IN denotes On
T9142 742-743 . denotes .
T9141 741-742 NNP denotes ]
T9140 739-741 CD denotes 19
T9139 738-739 NNP denotes [
T9138 734-737 NNP denotes TBI
T9137 728-733 IN denotes after
T9136 716-727 NN denotes hippocampus
T9135 713-715 IN denotes of
T9134 704-712 NN denotes subfield
T9133 700-703 NNP denotes CA3
T9132 696-699 DT denotes the
T9131 692-695 CC denotes and
T9130 685-691 NN denotes cortex
T9129 681-684 DT denotes the
T9128 678-680 IN denotes in
T9127 676-677 , denotes ,
T9126 664-676 NN denotes peroxidation
T9125 658-663 JJ denotes lipid
T9124 655-657 IN denotes of
T9123 648-654 NN denotes marker
T9122 646-647 DT denotes a
T9121 644-645 , denotes ,
T9120 643-644 -RRB- denotes )
T9119 638-643 JJ denotes 4-HNE
T9118 637-638 -LRB- denotes (
T9117 620-636 JJ denotes 4-Hydroxynonenal
T9116 616-619 IN denotes for
T9115 599-615 NN denotes immunoreactivity
R7328 T9026 T9029 nsubjpass which,involved
R7329 T9027 T9029 auxpass are,involved
R7331 T9028 T9029 dep all,involved
R7332 T9029 T9024 relcl involved,metabolites
R7334 T9030 T9029 prep in,involved
R7335 T9031 T9030 pobj TBI,in
R7337 T9032 T9006 punct .,proved
R7338 T9033 T9035 poss Our,study
R7339 T9002 T9003 amod Nrf2-ARE,pathway
R7340 T9034 T9035 amod previous,study
R7341 T9035 T9037 nsubj study,proved
R7342 T9036 T9037 aux has,proved
R7343 T9003 T9006 nsubjpass pathway,proved
R7344 T9037 T9037 ROOT proved,proved
R7345 T9038 T9039 det the,augmentation
R7346 T9039 T9037 dobj augmentation,proved
R7347 T9004 T9006 aux has,proved
R7348 T9040 T9039 prep of,augmentation
R7349 T9041 T9040 pobj Nrf2,of
R7350 T9042 T9039 prep in,augmentation
R7351 T9005 T9006 auxpass been,proved
R7352 T9043 T9044 compound brain,tissue
R7353 T9044 T9042 pobj tissue,in
R7354 T9045 T9037 prep after,proved
R7355 T9006 T9006 ROOT proved,proved
R7356 T9046 T9047 compound TBI,[
R7357 T9047 T9045 pobj [,after
R7358 T9007 T9008 aux to,be
R7359 T9048 T9047 nummod 17,[
R7360 T9049 T9047 conj ],[
R7361 T9008 T9006 xcomp be,proved
R7362 T9050 T9037 punct .,proved
R7363 T9051 T9052 amod Enhanced,level
R7364 T9052 T9052 ROOT level,level
R7365 T9009 T9011 det the,regulator
R7366 T9053 T9052 prep of,level
R7367 T9010 T9011 amod key,regulator
R7368 T9054 T9055 amod Nrf2,activates
R7369 T9055 T9053 pobj activates,of
R7370 T9056 T9055 dobj transcription,activates
R7371 T9011 T9008 attr regulator,be
R7374 T9012 T9011 prep in,regulator
R7375 T9013 T9012 pcomp reducing,in
R7376 T9014 T9015 amod oxidative,stress
R7377 T9015 T9013 dobj stress,reducing
R7378 T9016 T9015 punct ",",stress
R7381 T9017 T9018 amod inflammatory,damage
R7385 T9018 T9015 conj damage,stress
R7388 T9019 T9018 punct ",",damage
R7390 T9020 T9018 cc and,damage
R7391 T9021 T9018 conj accumulation,damage
R7394 T9022 T9021 prep of,accumulation
R7398 T9023 T9024 amod toxic,metabolites
R7401 T9024 T9022 pobj metabolites,of
R7407 T9078 T9079 compound quinone,oxidoreductase-1
R7409 T9079 T9052 appos oxidoreductase-1,level
R7410 T9080 T9079 punct (,oxidoreductase-1
R7411 T9081 T9079 appos NQO1,oxidoreductase-1
R7413 T9082 T9079 punct ),oxidoreductase-1
R7414 T9083 T9052 punct ",",level
R7415 T9084 T9087 nsubj which,reduce
R7417 T9085 T9087 aux would,reduce
R7418 T9086 T9087 advmod subsequently,reduce
R7420 T9087 T9052 relcl reduce,level
R7421 T9088 T9089 det the,damage
R7422 T9089 T9087 dobj damage,reduce
R7423 T9090 T9089 prep in,damage
R7424 T9091 T9090 pobj brain,in
R7426 T9092 T9094 nmod [,]
R7427 T9093 T9094 nummod 18,]
R7428 T9094 T9089 appos ],damage
R7429 T9095 T9052 punct .,level
R7430 T9096 T9097 compound Postinjury,administration
R7432 T9097 T9107 nsubj administration,improves
R7433 T9098 T9097 prep of,administration
R7434 T9099 T9098 pobj SFN,of
R7436 T9100 T9099 punct ",",SFN
R7438 T9101 T9102 det an,inducer
R7439 T9102 T9099 appos inducer,SFN
R7441 T9103 T9102 prep of,inducer
R7442 T9104 T9103 pobj Nrf2,of
R7443 T9105 T9107 punct ",",improves
R7444 T9166 T9165 pobj brain,in
R7445 T9106 T9107 advmod significantly,improves
R7446 T9107 T9107 ROOT improves,improves
R7447 T9108 T9109 amod spatial,memory
R7448 T9167 T9159 prep after,induces
R7449 T9109 T9107 dobj memory,improves
R7450 T9110 T9109 prep of,memory
R7451 T9111 T9110 pobj rat,of
R7452 T9168 T9169 compound TBI,[
R7453 T9112 T9107 cc and,improves
R7454 T9113 T9107 conj decreases,improves
R7455 T9114 T9115 det the,immunoreactivity
R7456 T9169 T9171 nmod [,]
R7457 T9115 T9113 dobj immunoreactivity,decreases
R7458 T9116 T9115 prep for,immunoreactivity
R7459 T9117 T9116 pobj 4-Hydroxynonenal,for
R7460 T9170 T9171 nummod 20,]
R7461 T9118 T9117 punct (,4-Hydroxynonenal
R7462 T9119 T9117 appos 4-HNE,4-Hydroxynonenal
R7463 T9120 T9117 punct ),4-Hydroxynonenal
R7464 T9171 T9167 pobj ],after
R7465 T9121 T9115 punct ",",immunoreactivity
R7466 T9122 T9123 det a,marker
R7467 T9123 T9115 appos marker,immunoreactivity
R7468 T9172 T9159 punct .,induces
R7469 T9124 T9123 prep of,marker
R7470 T9125 T9126 amod lipid,peroxidation
R7471 T9126 T9124 pobj peroxidation,of
R7472 T9173 T9177 advmod Here,revealed
R7473 T9127 T9113 punct ",",decreases
R7474 T9128 T9113 prep in,decreases
R7475 T9129 T9130 det the,cortex
R7476 T9130 T9128 pobj cortex,in
R7477 T9131 T9130 cc and,cortex
R7478 T9132 T9134 det the,subfield
R7479 T9174 T9177 punct ",",revealed
R7480 T9133 T9134 compound CA3,subfield
R7481 T9134 T9130 conj subfield,cortex
R7482 T9175 T9176 poss our,results
R7483 T9176 T9177 nsubj results,revealed
R7485 T9177 T9177 ROOT revealed,revealed
R7488 T9178 T9192 mark that,was
R7491 T9179 T9192 nsubj overexpression,was
R7495 T9180 T9179 prep of,overexpression
R7498 T9181 T9180 pobj TNF-α,of
R7499 T9182 T9181 punct ",",TNF-α
R7500 T9145 T9146 amod other,hand
R7501 T9146 T9143 pobj hand,On
R7502 T9183 T9181 conj IL-1β,TNF-α
R7503 T9147 T9150 punct ",",appear
R7504 T9148 T9149 amod Nrf2-deficient,mice
R7505 T9184 T9183 punct ",",IL-1β
R7506 T9149 T9150 nsubj mice,appear
R7507 T9150 T9150 ROOT appear,appear
R7508 T9185 T9183 conj IL-6,IL-1β
R7509 T9151 T9152 advmod more,susceptible
R7510 T9152 T9150 oprd susceptible,appear
R7511 T9153 T9152 prep to,susceptible
R7512 T9186 T9185 punct ",",IL-6
R7513 T9154 T9153 pobj TBI,to
R7514 T9155 T9150 punct .,appear
R7515 T9187 T9185 cc and,IL-6
R7516 T9188 T9185 conj MMP9,IL-6
R7517 T9189 T9179 prep after,overexpression
R7518 T9190 T9191 compound scratch,injury
R7519 T9191 T9189 pobj injury,after
R7520 T9192 T9194 auxpass was,aggravated
R7522 T9193 T9194 advmod more,aggravated
R7528 T9194 T9177 ccomp aggravated,revealed
R7532 T9195 T9194 prep in,aggravated
R7535 T9196 T9199 amod cultured,astrocytes
R7538 T9197 T9199 amod Nrf2,astrocytes
R7541 T9198 T9199 compound knockout,astrocytes
R7545 T9199 T9195 pobj astrocytes,in
R7549 T9200 T9194 prep than,aggravated
R7553 T9201 T9200 prep in,than
R7557 T9202 T9203 compound wildtype,astrocyetes
R7561 T9203 T9201 pobj astrocyetes,in
R7562 T9204 T9194 prep for,aggravated
R7563 T9205 T9207 det the,time
R7565 T9206 T9207 amod first,time
R7567 T9207 T9204 pobj time,for
R7570 T9208 T9194 punct ",",aggravated
R7577 T9209 T9194 cc and,aggravated
R7582 T9210 T9215 nsubj overexpression,led
R7585 T9211 T9210 prep of,overexpression
R7589 T9212 T9214 det these,mediators
R7590 T9213 T9214 amod proinflammatory,mediators
R7326 T9025 T9024 punct ",",metabolites
R7372 T9057 T9056 prep of,transcription
R7373 T9058 T9059 det a,group
R7379 T9059 T9057 pobj group,of
R7380 T9060 T9059 prep of,group
R7382 T9061 T9062 amod antioxidant,genes
R7383 T9062 T9060 pobj genes,of
R7384 T9063 T9062 punct ",",genes
R7386 T9064 T9065 amod such,as
R7387 T9065 T9062 prep as,genes
R7389 T9066 T9067 compound heme,oxygenase-1
R7392 T9067 T9065 pobj oxygenase-1,as
R7393 T9068 T9069 punct (,HO-1
R7395 T9069 T9067 appos HO-1,oxygenase-1
R7396 T9070 T9069 punct ),HO-1
R7397 T9071 T9067 cc and,oxygenase-1
R7399 T9072 T9067 conj NAD,oxygenase-1
R7400 T9073 T9072 punct (,NAD
R7402 T9074 T9072 appos P,NAD
R7403 T9075 T9072 punct ),NAD
R7405 T9076 T9065 pobj H,as
R7406 T9077 T9055 punct :,activates
R7484 T9135 T9134 prep of,subfield
R7486 T9136 T9135 pobj hippocampus,of
R7487 T9137 T9113 prep after,decreases
R7489 T9138 T9139 compound TBI,[
R7490 T9139 T9141 nmod [,]
R7492 T9140 T9141 nummod 19,]
R7493 T9141 T9137 pobj ],after
R7494 T9142 T9107 punct .,improves
R7496 T9143 T9150 prep On,appear
R7497 T9144 T9146 det the,hand
R7404 T9156 T9159 nsubj Depletion,induces
R7408 T9157 T9156 prep of,Depletion
R7412 T9158 T9157 pobj Nrf2,of
R7416 T9159 T9159 ROOT induces,induces
R7419 T9160 T9161 amod higher,expression
R7425 T9161 T9159 dobj expression,induces
R7431 T9162 T9161 prep of,expression
R7435 T9163 T9164 amod proinflammatory,mediators
R7437 T9164 T9162 pobj mediators,of
R7440 T9165 T9159 prep in,induces
R7592 T9214 T9211 pobj mediators,of
R7594 T9215 T9194 conj led,aggravated
R7598 T9216 T9215 prep to,led
R7602 T9217 T9219 amod more,deaths
R7604 T9218 T9219 compound astrocytes,deaths
R7608 T9219 T9216 pobj deaths,to
R7611 T9220 T9177 punct .,revealed

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T8607 371-375 Protein denotes HO-1
T8606 417-421 Protein denotes NQO1
T8605 353-369 Protein denotes heme oxygenase-1
T8604 283-287 Protein denotes Nrf2
T8603 212-224 Positive_regulation denotes augmentation
T8602 228-232 Protein denotes Nrf2
T8601 47-56 Regulation denotes regulator
T8600 5-8 Protein denotes ARE
T8599 0-4 Protein denotes Nrf2
T8635 945-959 Positive_regulation denotes overexpression
T8634 945-959 Positive_regulation denotes overexpression
T8633 945-959 Positive_regulation denotes overexpression
T8632 945-959 Gene_expression denotes overexpression
T8631 945-959 Gene_expression denotes overexpression
T8630 945-959 Gene_expression denotes overexpression
T8629 1045-1049 Protein denotes Nrf2
T8628 977-981 Protein denotes IL-6
T8627 970-975 Protein denotes IL-1β
T8626 963-968 Protein denotes TNF-α
T8625 815-824 Negative_regulation denotes Depletion
T8624 828-832 Protein denotes Nrf2
T8623 768-777 Negative_regulation denotes deficient
T8622 763-767 Protein denotes Nrf2
T8611 298-311 Transcription denotes transcription
T8610 298-311 Transcription denotes transcription
T8609 298-311 Transcription denotes transcription
T8608 265-273 Positive_regulation denotes Enhanced
T8621 585-594 Negative_regulation denotes decreases
T8620 585-594 Negative_regulation denotes decreases
T8619 585-594 Negative_regulation denotes decreases
T8618 519-526 Positive_regulation denotes inducer
T8617 519-526 Positive_regulation denotes inducer
T8616 530-534 Protein denotes Nrf2
T8615 511-514 Protein denotes SFN
T8614 288-297 Positive_regulation denotes activates
T8613 288-297 Positive_regulation denotes activates
T8612 288-297 Positive_regulation denotes activates
R6998 T8627 T8631 themeOf IL-1β,overexpression
R6999 T8628 T8632 themeOf IL-6,overexpression
R7000 T8630 T8633 themeOf overexpression,overexpression
R7001 T8631 T8634 themeOf overexpression,overexpression
R7002 T8632 T8635 themeOf overexpression,overexpression
R6981 T8600 T8601 themeOf ARE,regulator
R6982 T8602 T8603 themeOf Nrf2,augmentation
R6983 T8604 T8608 themeOf Nrf2,Enhanced
R6984 T8605 T8609 themeOf heme oxygenase-1,transcription
R6985 T8606 T8610 themeOf NQO1,transcription
R6986 T8607 T8611 themeOf HO-1,transcription
R6987 T8609 T8612 themeOf transcription,activates
R6988 T8610 T8613 themeOf transcription,activates
R6989 T8611 T8614 themeOf transcription,activates
R6990 T8615 T8617 themeOf SFN,inducer
R6991 T8615 T8619 themeOf SFN,decreases
R6992 T8616 T8618 themeOf Nrf2,inducer
R6993 T8617 T8620 themeOf inducer,decreases
R6994 T8618 T8621 themeOf inducer,decreases
R6995 T8622 T8623 themeOf Nrf2,deficient
R6996 T8624 T8625 themeOf Nrf2,Depletion
R6997 T8626 T8630 themeOf TNF-α,overexpression

testone

Id Subject Object Predicate Lexical cue
T7087 1050-1058 Negative_regulation denotes knockout
T7086 945-959 Positive_regulation denotes overexpression
T7085 815-824 Negative_regulation denotes Depletion
T7084 768-777 Negative_regulation denotes deficient
T7068 987-991 Protein denotes MMP9
T7067 977-981 Protein denotes IL-6
T7066 970-975 Protein denotes IL-1β
T7065 371-375 Protein denotes HO-1
T7064 353-369 Protein denotes heme oxygenase-1
R5813 T7065 T7064 equivalentTo HO-1,heme oxygenase-1
R5814 T7066 T7086 themeOf IL-1β,overexpression
R5815 T7067 T7086 themeOf IL-6,overexpression
R5816 T7068 T7086 themeOf MMP9,overexpression

test3

Id Subject Object Predicate Lexical cue
T7121 371-375 Protein denotes HO-1
T7120 353-369 Protein denotes heme oxygenase-1
T7164 1050-1058 Negative_regulation denotes knockout
T7163 987-991 Protein denotes MMP9
T7162 977-981 Protein denotes IL-6
T7161 970-975 Protein denotes IL-1β
T7160 945-959 Positive_regulation denotes overexpression
T7159 768-777 Negative_regulation denotes deficient
T7158 519-526 Positive_regulation denotes inducer
T7157 371-375 Protein denotes HO-1
T7156 353-369 Protein denotes heme oxygenase-1
T7124 987-991 Protein denotes MMP9
T7123 977-981 Protein denotes IL-6
T7122 970-975 Protein denotes IL-1β
R5848 T7157 T7156 equivalentTo HO-1,heme oxygenase-1
R5849 T7161 T7160 themeOf IL-1β,overexpression
R5850 T7162 T7160 themeOf IL-6,overexpression
R5851 T7163 T7160 themeOf MMP9,overexpression