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PMC:3291650 / 7120-9432 JSONTXT

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test3

Id Subject Object Predicate Lexical cue
T908 1407-1412 Protein denotes IRF-3
T907 1376-1383 Positive_regulation denotes induced
T906 1371-1375 Protein denotes TLR3
T905 1360-1365 Protein denotes RIG-I
T904 1351-1359 Regulation denotes regulate
T903 502-511 Negative_regulation denotes deficient
T902 411-416 Protein denotes IL-1R
T901 396-400 Protein denotes TLR4
T900 370-384 Protein denotes TNF receptor I
T839 1407-1412 Protein denotes IRF-3
T838 1371-1375 Protein denotes TLR3
T837 1360-1365 Protein denotes RIG-I
T836 411-416 Protein denotes IL-1R
T835 396-400 Protein denotes TLR4
T834 370-384 Protein denotes TNF receptor I
R549 T905 T907 causeOf RIG-I,induced
R550 T906 T907 causeOf TLR3,induced
R551 T907 T904 themeOf induced,regulate

2_test

Id Subject Object Predicate Lexical cue
22396652-11009421-98461837 386-388 11009421 denotes 37
22396652-22099304-98461838 391-393 22099304 denotes 39
22396652-15334086-98461839 402-404 15334086 denotes 40
22396652-20185725-98461840 418-420 20185725 denotes 41
22396652-11009421-98461841 592-594 11009421 denotes 37
22396652-22019834-98461842 728-730 22019834 denotes 42
22396652-21841782-98461843 733-735 21841782 denotes 48
22396652-19643665-98461844 1040-1042 19643665 denotes 45
22396652-16765340-98461845 1414-1416 16765340 denotes 49
22396652-15661910-98461846 1419-1421 15661910 denotes 52

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T2150 383-384 CD denotes I
T2149 374-382 NN denotes receptor
T2148 370-373 NN denotes TNF
T2147 367-369 IN denotes as
T2146 362-366 JJ denotes such
T2145 352-361 NN denotes receptors
T2144 343-351 JJ denotes multiple
T2143 340-342 TO denotes to
T2142 331-339 NN denotes response
T2141 328-330 IN denotes in
T2140 324-327 NN denotes A20
T2139 321-323 IN denotes by
T2138 311-320 NN denotes signaling
T2137 295-310 JJ denotes proinflammatory
T2136 292-294 IN denotes of
T2135 281-291 NN denotes regulation
T2134 272-280 JJ denotes negative
T2133 268-271 DT denotes the
T2132 265-267 IN denotes in
T2131 256-264 VB denotes involved
T2130 253-255 VB denotes be
T2129 250-252 TO denotes to
T2128 244-249 VB denotes shown
T2127 233-243 RB denotes previously
T2126 228-232 VB denotes were
T2125 217-227 NN denotes mechanisms
T2124 204-216 JJ denotes noncatalytic
T2123 200-203 CC denotes and
T2122 190-199 JJ denotes catalytic
T2121 185-189 CC denotes Both
T2120 175-183 NN denotes activity
T2119 168-174 NN denotes ligase
T2118 158-167 NN denotes ubiquitin
T2117 155-157 NN denotes E3
T2116 142-154 JJ denotes K48-specific
T2115 132-141 JJ denotes dependent
T2114 125-131 NN denotes finger
T2113 120-124 NN denotes zinc
T2112 111-119 JJ denotes atypical
T2111 103-110 VB denotes harbors
T2110 98-102 RB denotes also
T2109 94-97 NN denotes A20
T2108 92-93 -COMMA- denotes ,
T2107 79-92 RB denotes Interestingly
T2106 73-77 NN denotes DUBs
T2105 70-72 IN denotes of
T2104 63-69 NN denotes family
T2103 52-62 NN denotes OTU-domain
T2102 48-51 DT denotes the
T2101 45-47 TO denotes to
T2100 35-44 VB denotes belonging
T2099 28-34 NN denotes enzyme
T2098 10-27 JJ denotes ubiquitin-editing
T2097 7-9 DT denotes an
T2096 4-6 VB denotes is
T2095 0-3 NN denotes A20
T2477 2302-2311 NN denotes potential
T2476 2290-2301 JJ denotes therapeutic
T2475 2285-2289 VB denotes have
T2474 2279-2284 MD denotes might
T2473 2273-2278 NN denotes cells
T2472 2265-2272 JJ denotes myeloid
T2471 2262-2264 IN denotes in
T2470 2253-2261 NN denotes activity
T2469 2249-2252 NN denotes A20
T2468 2239-2248 VB denotes targeting
T2467 2236-2238 IN denotes by
T2466 2232-2235 NN denotes IAV
T2465 2229-2231 TO denotes to
T2464 2220-2228 NN denotes response
T2463 2213-2219 JJ denotes immune
T2462 2206-2212 JJ denotes innate
T2461 2202-2205 DT denotes the
T2460 2193-2201 VB denotes boosting
T2459 2188-2192 IN denotes that
T2458 2180-2187 VB denotes suggest
T2457 2172-2179 NN denotes results
T2456 2166-2171 DT denotes These
T2455 2155-2164 NN denotes clearance
T2454 2149-2154 JJ denotes viral
T2453 2140-2148 VB denotes enhanced
T2452 2136-2139 CC denotes and
T2451 2134-2135 -COMMA- denotes ,
T2450 2123-2134 NN denotes macrophages
T2449 2114-2122 JJ denotes alveolar
T2448 2110-2113 CC denotes and
T2447 2099-2109 NN denotes neutophils
T2446 2096-2098 IN denotes as
T2445 2091-2095 JJ denotes such
T2444 2085-2090 NN denotes cells
T2443 2078-2084 JJ denotes immune
T2442 2071-2077 JJ denotes innate
T2441 2068-2070 IN denotes of
T2440 2056-2067 NN denotes recruitment
T2439 2046-2055 VB denotes augmented
T2438 2044-2045 -COMMA- denotes ,
T2437 2034-2044 NN denotes production
T2436 2024-2033 NN denotes chemokine
T2435 2020-2023 CC denotes and
T2434 2011-2019 NN denotes cytokine
T2433 2001-2010 VB denotes increased
T2432 1996-2000 IN denotes with
T2431 1985-1995 VB denotes associated
T2430 1982-1984 VB denotes is
T2429 1977-1981 NN denotes mice
T2428 1966-1976 NN denotes A20myel-KO
T2427 1963-1965 IN denotes in
T2426 1959-1962 NN denotes IAV
T2425 1951-1958 IN denotes against
T2424 1940-1950 NN denotes Protection
T2423 1934-1938 NN denotes mice
T2422 1929-1933 NN denotes type
T2421 1924-1928 JJ denotes wild
T2420 1921-1923 TO denotes to
T2419 1912-1920 VB denotes compared
T2418 1902-1911 NN denotes infection
T2417 1897-1901 NN denotes lung
T2416 1893-1896 NN denotes IAV
T2415 1890-1892 TO denotes to
T2414 1881-1889 NN denotes response
T2413 1878-1880 IN denotes in
T2412 1868-1877 NN denotes morbidity
T2411 1860-1867 VB denotes reduced
T2410 1856-1859 CC denotes and
T2409 1847-1855 NN denotes survival
T2408 1838-1846 VB denotes enhanced
T2407 1833-1837 VB denotes show
T2406 1828-1832 NN denotes mice
T2405 1817-1827 NN denotes A20myel-KO
T2404 1815-1816 -COMMA- denotes ,
T2403 1802-1815 RB denotes Interestingly
T2402 1789-1800 NN denotes macrophages
T2401 1786-1788 IN denotes in
T2400 1776-1785 NN denotes signaling
T2399 1766-1775 JJ denotes antiviral
T2398 1762-1765 CC denotes and
T2397 1746-1761 JJ denotes proinflammatory
T2396 1734-1745 JJ denotes IAV-induced
T2395 1731-1733 IN denotes of
T2394 1721-1730 NN denotes regulator
T2393 1712-1720 JJ denotes negative
T2340 1424-1431 RB denotes However
T2339 1421-1422 -RRB- denotes ]
T2338 1419-1421 CD denotes 52
T2337 1418-1419 -LRB- denotes [
T2336 1417-1418 CD denotes –
T2335 1416-1417 -RRB- denotes ]
T2334 1414-1416 CD denotes 49
T2333 1413-1414 -LRB- denotes [
T2332 1407-1412 NN denotes IRF-3
T2331 1403-1406 CC denotes and
T2330 1397-1402 NN denotes NF-κB
T2329 1394-1396 TO denotes to
T2328 1384-1393 NN denotes signaling
T2327 1371-1383 JJ denotes TLR3-induced
T2326 1367-1370 CC denotes and
T2325 1360-1366 NN denotes RIG-I-
T2324 1351-1359 VB denotes regulate
T2323 1347-1350 MD denotes may
T2322 1343-1346 NN denotes A20
T2321 1338-1342 IN denotes that
T2320 1327-1337 VB denotes indicating
T2319 1325-1326 -COMMA- denotes ,
T2318 1320-1325 NN denotes lines
T2317 1315-1319 NN denotes cell
T2316 1306-1314 JJ denotes specific
T2315 1303-1305 IN denotes in
T2314 1293-1302 NN denotes silencing
T2313 1290-1292 CC denotes or
T2312 1275-1289 NN denotes overexpression
T2311 1269-1274 VB denotes using
T2310 1261-1268 NN denotes studies
T2309 1255-1260 FW denotes vitro
T2308 1252-1254 FW denotes in
T2307 1249-1251 IN denotes of
T2306 1242-1248 NN denotes number
T2305 1240-1241 DT denotes a
T2304 1237-1239 TO denotes to
T2303 1229-1236 VB denotes limited
T2302 1225-1228 CC denotes and
T2301 1215-1224 VB denotes described
T2300 1210-1214 RB denotes well
T2299 1205-1209 RB denotes less
T2298 1202-1204 VB denotes is
T2297 1192-1201 NN denotes responses
T2296 1185-1191 JJ denotes immune
T2295 1175-1184 JJ denotes antiviral
T2294 1172-1174 IN denotes of
T2293 1161-1171 NN denotes regulation
T2292 1157-1160 DT denotes the
T2291 1154-1156 IN denotes in
T2290 1150-1153 NN denotes A20
T2289 1147-1149 IN denotes of
T2288 1142-1146 NN denotes role
T2287 1138-1141 DT denotes the
T2286 1136-1137 -COMMA- denotes ,
T2285 1127-1136 NN denotes responses
T2284 1111-1126 JJ denotes proinflammatory
T2283 1108-1110 IN denotes of
T2282 1097-1107 NN denotes regulation
T2281 1093-1096 DT denotes the
T2280 1090-1092 IN denotes in
T2279 1081-1089 NN denotes function
T2278 1069-1080 VB denotes established
T2277 1064-1068 RB denotes well
T2276 1060-1063 PRP-DOLLAR- denotes its
T2275 1057-1059 TO denotes to
T2274 1048-1056 NN denotes contrast
T2273 1045-1047 IN denotes In
T2272 1042-1043 -RRB- denotes ]
T2271 1040-1042 CD denotes 45
T2270 1039-1040 -LRB- denotes [
T2269 1026-1038 NN denotes inflammation
T2268 1018-1025 JJ denotes chronic
T2267 1014-1017 CC denotes and
T2266 1005-1013 NN denotes diseases
T2265 994-1004 JJ denotes autoimmune
T2264 986-993 JJ denotes several
T2263 981-985 IN denotes with
T2262 970-980 VB denotes associated
T2261 966-969 VB denotes are
T2260 961-965 WDT denotes that
T2259 955-960 NN denotes locus
T2258 951-954 NN denotes A20
T2257 947-950 DT denotes the
T2256 944-946 IN denotes in
T2255 930-943 NN denotes polymorphisms
T2254 927-929 IN denotes of
T2253 912-926 NN denotes identification
T2252 908-911 DT denotes the
T2251 900-907 IN denotes through
T2250 888-899 VB denotes illustrated
T2249 883-887 VB denotes been
T2248 874-882 RB denotes recently
T2247 870-873 VB denotes has
T2246 862-869 NN denotes disease
T2245 856-861 JJ denotes human
T2244 852-855 IN denotes for
T2243 843-851 NN denotes findings
T2242 837-842 DT denotes these
T2241 834-836 IN denotes of
T2240 824-833 NN denotes relevance
T2239 820-823 DT denotes The
T2238 810-818 NN denotes response
T2237 797-809 JJ denotes inflammatory
T2236 793-796 DT denotes the
T2235 790-792 IN denotes on
T2234 784-789 NN denotes brake
T2233 774-783 JJ denotes important
T2232 771-773 DT denotes an
T2231 768-770 VB denotes is
T2230 764-767 NN denotes A20
T2229 759-763 IN denotes that
T2228 746-758 VB denotes illustrating
T2227 738-745 RB denotes further
T2226 736-737 -COMMA- denotes ,
T2225 735-736 -RRB- denotes ]
T2224 733-735 CD denotes 48
T2223 732-733 -LRB- denotes [
T2222 731-732 CD denotes –
T2221 730-731 -RRB- denotes ]
T2220 728-730 CD denotes 42
T2219 727-728 -LRB- denotes [
T2218 714-726 NN denotes inflammation
T2217 706-713 JJ denotes chronic
T2216 702-705 CC denotes and
T2215 689-701 NN denotes autoimmunity
T2214 684-688 IN denotes with
T2213 673-683 VB denotes associated
T2212 670-672 VB denotes be
T2211 667-669 TO denotes to
T2210 661-666 VB denotes shown
T2209 657-660 VB denotes was
T2208 651-656 NN denotes types
T2207 646-650 NN denotes cell
T2206 637-645 JJ denotes specific
T2205 634-636 IN denotes in
T2204 630-633 NN denotes A20
T2203 627-629 IN denotes of
T2202 617-626 NN denotes targeting
T2201 612-616 NN denotes gene
T2200 610-611 -COMMA- denotes ,
T2199 602-610 RB denotes recently
T2198 597-601 RB denotes More
T2197 594-595 -RRB- denotes ]
T2196 592-594 CD denotes 37
T2195 591-592 -LRB- denotes [
T2194 582-590 NN denotes cachexia
T2193 578-581 CC denotes and
T2192 565-577 NN denotes inflammation
T2191 553-564 JJ denotes multi-organ
T2190 546-552 JJ denotes severe
T2189 543-545 TO denotes to
T2188 539-542 JJ denotes due
T2187 533-538 NN denotes birth
T2186 527-532 IN denotes after
T2185 521-526 RB denotes early
T2184 517-520 VB denotes die
T2183 512-516 NN denotes mice
T2182 502-511 JJ denotes deficient
T2181 498-501 NN denotes A20
T2180 493-497 IN denotes that
T2179 488-492 NN denotes fact
T2178 484-487 DT denotes the
T2177 481-483 IN denotes by
T2176 468-480 VB denotes demonstrated
T2175 460-467 RB denotes clearly
T2174 457-459 VB denotes is
T2173 453-456 NN denotes A20
T2172 450-452 IN denotes of
T2171 445-449 NN denotes role
T2170 427-444 JJ denotes anti-inflammatory
T2169 423-426 DT denotes The
T2168 420-421 -RRB- denotes ]
T2167 418-420 CD denotes 41
T2166 417-418 -LRB- denotes [
T2165 411-416 NN denotes IL-1R
T2164 407-410 CC denotes and
T2163 405-406 -COMMA- denotes ,
T2162 404-405 -RRB- denotes ]
T2161 402-404 CD denotes 40
T2160 401-402 -LRB- denotes [
T2159 396-400 NN denotes TLR4
T2158 394-395 -COMMA- denotes ,
T2157 393-394 -RRB- denotes ]
T2156 391-393 CD denotes 39
T2155 390-391 -LRB- denotes [
T2154 389-390 CD denotes –
T2153 388-389 -RRB- denotes ]
T2152 386-388 CD denotes 37
T2151 385-386 -LRB- denotes [
T2392 1704-1711 JJ denotes crucial
T2391 1702-1703 DT denotes a
T2390 1699-1701 VB denotes is
T2389 1695-1698 NN denotes A20
T2388 1690-1694 IN denotes that
T2387 1681-1689 NN denotes evidence
T2386 1673-1680 VB denotes provide
T2385 1668-1672 RB denotes here
T2384 1665-1667 PRP denotes we
T2383 1663-1664 -COMMA- denotes ,
T2382 1659-1663 NN denotes mice
T2381 1653-1658 DT denotes these
T2380 1650-1652 IN denotes of
T2379 1642-1649 VB denotes derived
T2378 1636-1641 NN denotes cells
T2377 1628-1635 JJ denotes primary
T2376 1624-1627 CC denotes and
T2375 1620-1623 NN denotes lab
T2374 1616-1619 PRP-DOLLAR- denotes our
T2373 1613-1615 IN denotes in
T2372 1603-1612 VB denotes generated
T2371 1594-1602 RB denotes recently
T2370 1589-1593 VB denotes were
T2369 1584-1588 WDT denotes that
T2368 1582-1583 -RRB- denotes )
T2367 1572-1582 NN denotes A20myel-KO
T2366 1571-1572 -LRB- denotes (
T2365 1566-1570 NN denotes mice
T2364 1557-1565 NN denotes knockout
T2363 1553-1556 NN denotes A20
T2362 1544-1552 JJ denotes specific
T2361 1539-1543 NN denotes cell
T2360 1531-1538 JJ denotes myeloid
T2359 1525-1530 VB denotes Using
T2358 1514-1523 VB denotes clarified
T2357 1511-1513 VB denotes be
T2356 1508-1510 TO denotes to
T2355 1500-1507 VB denotes remains
T2354 1490-1499 NN denotes infection
T2353 1484-1489 JJ denotes viral
T2352 1481-1483 TO denotes to
T2351 1472-1480 NN denotes response
T2350 1468-1471 DT denotes the
T2349 1465-1467 IN denotes in
T2348 1461-1464 NN denotes A20
T2347 1458-1460 IN denotes of
T2346 1453-1457 NN denotes role
T2345 1448-1452 FW denotes vivo
T2344 1445-1447 FW denotes in
T2343 1437-1444 JJ denotes precise
T2342 1433-1436 DT denotes the
T2341 1431-1432 -COMMA- denotes ,
R1355 T2142 T2141 arg2Of response,in
R1363 T2142 T2143 arg1Of response,to
R1364 T2145 T2143 arg2Of receptors,to
R1368 T2095 T2096 arg1Of A20,is
R1369 T2145 T2144 arg1Of receptors,multiple
R1370 T2099 T2096 arg2Of enzyme,is
R1371 T2099 T2097 arg1Of enzyme,an
R1372 T2099 T2098 arg1Of enzyme,ubiquitin-editing
R1373 T2099 T2100 arg1Of enzyme,belonging
R1374 T2100 T2101 arg1Of belonging,to
R1375 T2145 T2147 arg1Of receptors,as
R1376 T2104 T2101 arg2Of family,to
R1377 T2147 T2146 arg1Of as,such
R1378 T2104 T2102 arg1Of family,the
R1379 T2104 T2103 arg1Of family,OTU-domain
R1380 T2104 T2105 arg1Of family,of
R1381 T2106 T2105 arg2Of DUBs,of
R1382 T2149 T2148 arg1Of receptor,TNF
R1383 T2149 T2150 arg1Of receptor,I
R1384 T2152 T2151 arg2Of 37,[
R1385 T2109 T2111 arg1Of A20,harbors
R1386 T2111 T2107 arg1Of harbors,Interestingly
R1387 T2111 T2108 arg1Of harbors,","
R1388 T2111 T2110 arg1Of harbors,also
R1389 T2153 T2151 arg3Of ],[
R1390 T2154 T2149 arg1Of –,receptor
R1391 T2154 T2151 arg1Of –,[
R1392 T2154 T2155 arg1Of –,[
R1393 T2120 T2111 arg2Of activity,harbors
R1394 T2120 T2112 arg1Of activity,atypical
R1395 T2120 T2113 arg1Of activity,zinc
R1396 T2120 T2114 arg1Of activity,finger
R1397 T2120 T2115 arg1Of activity,dependent
R1398 T2120 T2116 arg1Of activity,K48-specific
R1399 T2120 T2117 arg1Of activity,E3
R1400 T2120 T2118 arg1Of activity,ubiquitin
R1401 T2120 T2119 arg1Of activity,ligase
R1402 T2154 T2158 arg1Of –,","
R1403 T2156 T2155 arg2Of 39,[
R1404 T2122 T2123 arg1Of catalytic,and
R1405 T2124 T2123 arg2Of noncatalytic,and
R1406 T2125 T2121 arg1Of mechanisms,Both
R1407 T2125 T2122 arg1Of mechanisms,catalytic
R1408 T2125 T2124 arg1Of mechanisms,noncatalytic
R1409 T2125 T2126 arg1Of mechanisms,were
R1410 T2125 T2128 arg2Of mechanisms,shown
R1411 T2125 T2130 arg1Of mechanisms,be
R1412 T2125 T2131 arg2Of mechanisms,involved
R1413 T2157 T2155 arg3Of ],[
R1414 T2128 T2126 arg2Of shown,were
R1415 T2128 T2127 arg1Of shown,previously
R1416 T2158 T2164 arg1Of ",",and
R1417 T2131 T2128 arg3Of involved,shown
R1418 T2131 T2129 arg1Of involved,to
R1419 T2131 T2130 arg2Of involved,be
R1420 T2131 T2132 arg1Of involved,in
R1421 T2131 T2141 arg1Of involved,in
R1422 T2159 T2158 arg2Of TLR4,","
R1423 T2135 T2132 arg2Of regulation,in
R1424 T2135 T2133 arg1Of regulation,the
R1425 T2135 T2134 arg1Of regulation,negative
R1426 T2135 T2136 arg1Of regulation,of
R1427 T2135 T2139 arg1Of regulation,by
R1428 T2138 T2136 arg2Of signaling,of
R1429 T2138 T2137 arg1Of signaling,proinflammatory
R1430 T2140 T2139 arg2Of A20,by
R1431 T2159 T2160 arg1Of TLR4,[
R1432 T2161 T2160 arg2Of 40,[
R1433 T2162 T2160 arg3Of ],[
R1434 T2164 T2147 arg2Of and,as
R1435 T2238 T2235 arg2Of response,on
R1436 T2238 T2236 arg1Of response,the
R1437 T2238 T2237 arg1Of response,inflammatory
R1438 T2164 T2163 arg1Of and,","
R1439 T2240 T2239 arg1Of relevance,The
R1440 T2240 T2241 arg1Of relevance,of
R1441 T2240 T2244 arg1Of relevance,for
R1442 T2240 T2247 arg1Of relevance,has
R1443 T2240 T2249 arg1Of relevance,been
R1444 T2240 T2250 arg2Of relevance,illustrated
R1445 T2165 T2164 arg2Of IL-1R,and
R1446 T2243 T2241 arg2Of findings,of
R1447 T2243 T2242 arg1Of findings,these
R1448 T2165 T2166 arg1Of IL-1R,[
R1449 T2246 T2244 arg2Of disease,for
R1450 T2246 T2245 arg1Of disease,human
R1451 T2167 T2166 arg2Of 41,[
R1452 T2168 T2166 arg3Of ],[
R1453 T2250 T2247 arg2Of illustrated,has
R1454 T2250 T2248 arg1Of illustrated,recently
R1455 T2250 T2249 arg2Of illustrated,been
R1456 T2250 T2251 arg1Of illustrated,through
R1457 T2171 T2169 arg1Of role,The
R1458 T2253 T2251 arg2Of identification,through
R1459 T2253 T2252 arg1Of identification,the
R1460 T2253 T2254 arg1Of identification,of
R1461 T2171 T2170 arg1Of role,anti-inflammatory
R1462 T2255 T2254 arg2Of polymorphisms,of
R1463 T2255 T2256 arg1Of polymorphisms,in
R1464 T2255 T2260 arg1Of polymorphisms,that
R1465 T2255 T2261 arg1Of polymorphisms,are
R1466 T2255 T2262 arg2Of polymorphisms,associated
R1467 T2171 T2172 arg1Of role,of
R1468 T2171 T2174 arg1Of role,is
R1469 T2171 T2176 arg2Of role,demonstrated
R1470 T2259 T2256 arg2Of locus,in
R1471 T2259 T2257 arg1Of locus,the
R1472 T2259 T2258 arg1Of locus,A20
R1473 T2173 T2172 arg2Of A20,of
R1474 T2262 T2261 arg2Of associated,are
R1475 T2262 T2263 arg1Of associated,with
R1476 T2266 T2264 arg1Of diseases,several
R1477 T2266 T2265 arg1Of diseases,autoimmune
R1478 T2266 T2267 arg1Of diseases,and
R1479 T2267 T2263 arg2Of and,with
R1480 T2176 T2174 arg2Of demonstrated,is
R1481 T2269 T2267 arg2Of inflammation,and
R1482 T2269 T2268 arg1Of inflammation,chronic
R1483 T2269 T2270 arg1Of inflammation,[
R1484 T2271 T2270 arg2Of 45,[
R1485 T2272 T2270 arg3Of ],[
R1486 T2273 T2275 arg1Of In,to
R1487 T2176 T2175 arg1Of demonstrated,clearly
R1488 T2274 T2273 arg2Of contrast,In
R1489 T2179 T2176 arg1Of fact,demonstrated
R1490 T2278 T2277 arg1Of established,well
R1491 T2179 T2177 arg2Of fact,by
R1492 T2279 T2273 arg3Of function,In
R1493 T2279 T2276 arg1Of function,its
R1494 T2279 T2278 arg1Of function,established
R1495 T2279 T2280 arg1Of function,in
R1496 T2179 T2178 arg1Of fact,the
R1497 T2282 T2280 arg2Of regulation,in
R1498 T2282 T2281 arg1Of regulation,the
R1499 T2282 T2283 arg1Of regulation,of
R1500 T2183 T2181 arg1Of mice,A20
R1501 T2285 T2283 arg2Of responses,of
R1502 T2285 T2284 arg1Of responses,proinflammatory
R1503 T2288 T2287 arg1Of role,the
R1504 T2288 T2289 arg1Of role,of
R1505 T2288 T2291 arg1Of role,in
R1506 T2288 T2298 arg1Of role,is
R1507 T2288 T2301 arg2Of role,described
R1508 T2288 T2303 arg2Of role,limited
R1509 T2290 T2289 arg2Of A20,of
R1510 T2183 T2182 arg1Of mice,deficient
R1511 T2183 T2184 arg1Of mice,die
R1512 T2184 T2179 arg2Of die,fact
R1513 T2293 T2291 arg2Of regulation,in
R1514 T2293 T2292 arg1Of regulation,the
R1515 T2293 T2294 arg1Of regulation,of
R1516 T2184 T2180 arg1Of die,that
R1517 T2297 T2294 arg2Of responses,of
R1518 T2297 T2295 arg1Of responses,antiviral
R1519 T2297 T2296 arg1Of responses,immune
R1520 T2184 T2185 arg1Of die,early
R1521 T2184 T2186 arg1Of die,after
R1522 T2300 T2299 arg1Of well,less
R1523 T2187 T2186 arg2Of birth,after
R1524 T2301 T2302 arg1Of described,and
R1525 T2302 T2273 arg1Of and,In
R1526 T2302 T2286 arg1Of and,","
R1527 T2302 T2298 arg2Of and,is
R1528 T2302 T2300 arg1Of and,well
R1529 T2303 T2302 arg2Of limited,and
R1530 T2303 T2304 arg1Of limited,to
R1531 T2306 T2304 arg2Of number,to
R1532 T2306 T2305 arg1Of number,a
R1533 T2306 T2307 arg1Of number,of
R1534 T2309 T2308 arg1Of vitro,in
R1535 T2310 T2307 arg2Of studies,of
R1536 T2310 T2309 arg1Of studies,vitro
R1537 T2310 T2311 arg1Of studies,using
R1538 T2311 T2319 arg1Of using,","
R1539 T2311 T2320 modOf using,indicating
R1540 T2187 T2188 arg1Of birth,due
R1541 T2312 T2313 arg1Of overexpression,or
R1542 T2313 T2311 arg2Of or,using
R1543 T2313 T2315 arg1Of or,in
R1544 T2188 T2189 arg1Of due,to
R1545 T2314 T2313 arg2Of silencing,or
R1546 T2192 T2190 arg1Of inflammation,severe
R1547 T2318 T2315 arg2Of lines,in
R1548 T2318 T2316 arg1Of lines,specific
R1549 T2318 T2317 arg1Of lines,cell
R1550 T2192 T2191 arg1Of inflammation,multi-organ
R1551 T2322 T2323 arg1Of A20,may
R1552 T2192 T2193 arg1Of inflammation,and
R1553 T2193 T2189 arg2Of and,to
R1554 T2322 T2324 arg1Of A20,regulate
R1555 T2194 T2193 arg2Of cachexia,and
R1556 T2324 T2320 arg2Of regulate,indicating
R1557 T2324 T2321 arg1Of regulate,that
R1558 T2324 T2323 arg2Of regulate,may
R1559 T2325 T2326 arg1Of RIG-I-,and
R1560 T2194 T2195 arg1Of cachexia,[
R1561 T2326 T2329 arg1Of and,to
R1562 T2326 T2331 arg1Of and,and
R1563 T2196 T2195 arg2Of 37,[
R1564 T2328 T2326 arg2Of signaling,and
R1565 T2328 T2327 arg1Of signaling,TLR3-induced
R1566 T2330 T2329 arg2Of NF-κB,to
R1567 T2331 T2324 arg2Of and,regulate
R1568 T2197 T2195 arg3Of ],[
R1569 T2199 T2198 arg1Of recently,More
R1570 T2334 T2333 arg2Of 49,[
R1571 T2202 T2201 arg1Of targeting,gene
R1572 T2335 T2333 arg3Of ],[
R1573 T2336 T2331 arg2Of –,and
R1574 T2336 T2332 arg1Of –,IRF-3
R1575 T2336 T2333 arg1Of –,[
R1576 T2336 T2337 arg1Of –,[
R1577 T2338 T2337 arg2Of 52,[
R1578 T2339 T2337 arg3Of ],[
R1579 T2202 T2203 arg1Of targeting,of
R1580 T2202 T2205 arg1Of targeting,in
R1581 T2202 T2209 arg1Of targeting,was
R1582 T2202 T2210 arg2Of targeting,shown
R1583 T2345 T2344 arg1Of vivo,in
R1584 T2202 T2212 arg1Of targeting,be
R1585 T2346 T2342 arg1Of role,the
R1586 T2346 T2343 arg1Of role,precise
R1587 T2346 T2345 arg1Of role,vivo
R1588 T2346 T2347 arg1Of role,of
R1589 T2346 T2349 arg1Of role,in
R1590 T2346 T2355 arg1Of role,remains
R1591 T2346 T2357 arg1Of role,be
R1592 T2346 T2358 arg2Of role,clarified
R1593 T2348 T2347 arg2Of A20,of
R1594 T2202 T2213 arg2Of targeting,associated
R1595 T2202 T2228 arg1Of targeting,illustrating
R1596 T2351 T2349 arg2Of response,in
R1597 T2351 T2350 arg1Of response,the
R1598 T2351 T2352 arg1Of response,to
R1599 T2204 T2203 arg2Of A20,of
R1600 T2354 T2352 arg2Of infection,to
R1601 T2354 T2353 arg1Of infection,viral
R1602 T2355 T2340 arg1Of remains,However
R1603 T2355 T2341 arg1Of remains,","
R1604 T2208 T2205 arg2Of types,in
R1605 T2358 T2355 arg2Of clarified,remains
R1606 T2358 T2356 arg1Of clarified,to
R1607 T2358 T2357 arg2Of clarified,be
R1608 T2208 T2206 arg1Of types,specific
R1609 T2208 T2207 arg1Of types,cell
R1610 T2210 T2199 arg1Of shown,recently
R1611 T2365 T2359 arg2Of mice,Using
R1612 T2365 T2360 arg1Of mice,myeloid
R1613 T2365 T2361 arg1Of mice,cell
R1614 T2365 T2362 arg1Of mice,specific
R1615 T2365 T2363 arg1Of mice,A20
R1616 T2365 T2364 arg1Of mice,knockout
R1617 T2365 T2366 arg1Of mice,(
R1618 T2365 T2369 arg1Of mice,that
R1619 T2365 T2370 arg1Of mice,were
R1620 T2365 T2372 arg2Of mice,generated
R1621 T2367 T2366 arg2Of A20myel-KO,(
R1622 T2368 T2366 arg3Of ),(
R1623 T2210 T2200 arg1Of shown,","
R1624 T2372 T2370 arg2Of generated,were
R1625 T2372 T2371 arg1Of generated,recently
R1626 T2372 T2373 arg1Of generated,in
R1627 T2375 T2376 arg1Of lab,and
R1628 T2210 T2209 arg2Of shown,was
R1629 T2210 T2226 arg1Of shown,","
R1630 T2377 T2376 arg2Of primary,and
R1631 T2210 T2228 modOf shown,illustrating
R1632 T2378 T2373 arg2Of cells,in
R1633 T2378 T2374 arg1Of cells,our
R1634 T2378 T2375 arg1Of cells,lab
R1635 T2378 T2377 arg1Of cells,primary
R1636 T2378 T2379 arg2Of cells,derived
R1637 T2379 T2380 arg1Of derived,of
R1638 T2213 T2210 arg3Of associated,shown
R1639 T2382 T2380 arg2Of mice,of
R1640 T2382 T2381 arg1Of mice,these
R1641 T2384 T2359 arg1Of we,Using
R1642 T2384 T2386 arg1Of we,provide
R1643 T2386 T2359 modOf provide,Using
R1644 T2386 T2383 arg1Of provide,","
R1645 T2386 T2385 arg1Of provide,here
R1646 T2387 T2386 arg2Of evidence,provide
R1647 T2213 T2211 arg1Of associated,to
R1648 T2213 T2212 arg2Of associated,be
R1649 T2213 T2214 arg1Of associated,with
R1650 T2389 T2390 arg1Of A20,is
R1651 T2390 T2387 arg2Of is,evidence
R1652 T2390 T2388 arg1Of is,that
R1653 T2215 T2216 arg1Of autoimmunity,and
R1654 T2394 T2390 arg2Of regulator,is
R1655 T2394 T2391 arg1Of regulator,a
R1656 T2394 T2392 arg1Of regulator,crucial
R1657 T2394 T2393 arg1Of regulator,negative
R1658 T2394 T2395 arg1Of regulator,of
R1659 T2216 T2214 arg2Of and,with
R1660 T2220 T2219 arg2Of 42,[
R1661 T2397 T2398 arg1Of proinflammatory,and
R1662 T2399 T2398 arg2Of antiviral,and
R1663 T2400 T2395 arg2Of signaling,of
R1664 T2400 T2396 arg1Of signaling,IAV-induced
R1665 T2400 T2397 arg1Of signaling,proinflammatory
R1666 T2400 T2399 arg1Of signaling,antiviral
R1667 T2400 T2401 arg1Of signaling,in
R1668 T2402 T2401 arg2Of macrophages,in
R1669 T2221 T2219 arg3Of ],[
R1670 T2222 T2216 arg2Of –,and
R1671 T2406 T2405 arg1Of mice,A20myel-KO
R1672 T2406 T2407 arg1Of mice,show
R1673 T2407 T2403 arg1Of show,Interestingly
R1674 T2407 T2404 arg1Of show,","
R1675 T2407 T2413 arg1Of show,in
R1676 T2407 T2419 arg1Of show,compared
R1677 T2409 T2408 arg2Of survival,enhanced
R1678 T2409 T2410 arg1Of survival,and
R1679 T2410 T2407 arg2Of and,show
R1680 T2222 T2217 arg1Of –,chronic
R1681 T2412 T2410 arg2Of morbidity,and
R1682 T2412 T2411 arg2Of morbidity,reduced
R1683 T2222 T2218 arg1Of –,inflammation
R1684 T2414 T2413 arg2Of response,in
R1685 T2414 T2415 arg1Of response,to
R1686 T2222 T2219 arg1Of –,[
R1687 T2222 T2223 arg1Of –,[
R1688 T2224 T2223 arg2Of 48,[
R1689 T2418 T2415 arg2Of infection,to
R1690 T2418 T2416 arg1Of infection,IAV
R1691 T2418 T2417 arg1Of infection,lung
R1692 T2420 T2419 arg2Of to,compared
R1693 T2225 T2223 arg3Of ],[
R1694 T2423 T2420 arg2Of mice,to
R1695 T2423 T2421 arg1Of mice,wild
R1696 T2423 T2422 arg1Of mice,type
R1697 T2424 T2425 arg1Of Protection,against
R1698 T2424 T2427 arg1Of Protection,in
R1699 T2424 T2430 arg1Of Protection,is
R1700 T2424 T2431 arg2Of Protection,associated
R1701 T2424 T2439 arg1Of Protection,augmented
R1702 T2424 T2453 arg1Of Protection,enhanced
R1703 T2426 T2425 arg2Of IAV,against
R1704 T2228 T2227 arg1Of illustrating,further
R1705 T2429 T2427 arg2Of mice,in
R1706 T2429 T2428 arg1Of mice,A20myel-KO
R1707 T2431 T2430 arg2Of associated,is
R1708 T2431 T2432 arg1Of associated,with
R1709 T2431 T2438 arg1Of associated,","
R1710 T2230 T2231 arg1Of A20,is
R1711 T2231 T2228 arg2Of is,illustrating
R1712 T2231 T2229 arg1Of is,that
R1713 T2234 T2231 arg2Of brake,is
R1714 T2434 T2433 arg2Of cytokine,increased
R1715 T2434 T2435 arg1Of cytokine,and
R1716 T2435 T2432 arg2Of and,with
R1717 T2234 T2232 arg1Of brake,an
R1718 T2437 T2435 arg2Of production,and
R1719 T2437 T2436 arg1Of production,chemokine
R1720 T2234 T2233 arg1Of brake,important
R1721 T2438 T2452 arg1Of ",",and
R1722 T2234 T2235 arg1Of brake,on
R1723 T2439 T2438 arg2Of augmented,","
R1725 T2440 T2439 arg2Of recruitment,augmented
R1726 T2440 T2441 arg1Of recruitment,of
R1727 T2444 T2441 arg2Of cells,of
R1728 T2444 T2442 arg1Of cells,innate
R1729 T2444 T2443 arg1Of cells,immune
R1730 T2444 T2446 arg1Of cells,as
R1731 T2446 T2445 arg1Of as,such
R1732 T2447 T2448 arg1Of neutophils,and
R1733 T2448 T2446 arg2Of and,as
R1734 T2450 T2448 arg2Of macrophages,and
R1735 T2450 T2449 arg1Of macrophages,alveolar
R1737 T2452 T2451 arg1Of and,","
R1738 T2453 T2452 arg2Of enhanced,and
R1740 T2455 T2453 arg2Of clearance,enhanced
R1742 T2455 T2454 arg1Of clearance,viral
R1745 T2457 T2456 arg1Of results,These
R1746 T2457 T2458 arg1Of results,suggest
R1748 T2460 T2467 arg1Of boosting,by
R1751 T2460 T2474 arg1Of boosting,might
R1752 T2460 T2475 arg1Of boosting,have
R1754 T2464 T2460 arg2Of response,boosting
R1755 T2464 T2461 arg1Of response,the
R1756 T2464 T2462 arg1Of response,innate
R1757 T2464 T2463 arg1Of response,immune
R1758 T2464 T2465 arg1Of response,to
R1759 T2466 T2465 arg2Of IAV,to
R1761 T2468 T2467 arg2Of targeting,by
R1763 T2470 T2468 arg2Of activity,targeting
R1764 T2470 T2469 arg1Of activity,A20
R1765 T2470 T2471 arg1Of activity,in
R1767 T2473 T2471 arg2Of cells,in
R1768 T2473 T2472 arg1Of cells,myeloid
R1769 T2475 T2458 arg2Of have,suggest
R1770 T2475 T2459 arg1Of have,that
R1771 T2475 T2474 arg2Of have,might
R1773 T2477 T2475 arg2Of potential,have
R1774 T2477 T2476 arg1Of potential,therapeutic

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T1085 1407-1412 Protein denotes IRF-3
T1084 1371-1375 Protein denotes TLR3
T1083 1360-1365 Protein denotes RIG-I
T1082 411-416 Protein denotes IL-1R
T1081 396-400 Protein denotes TLR4
T1080 370-384 Protein denotes TNF receptor I

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T3682 396-400 http://www.uniprot.org/uniprot/O00206 denotes TLR4
T3681 2249-2252 http://www.uniprot.org/uniprot/P21580 denotes A20
T3680 1695-1698 http://www.uniprot.org/uniprot/P21580 denotes A20
T3679 1553-1556 http://www.uniprot.org/uniprot/P21580 denotes A20
T3678 1461-1464 http://www.uniprot.org/uniprot/P21580 denotes A20
T3677 1343-1346 http://www.uniprot.org/uniprot/P21580 denotes A20
T3676 1150-1153 http://www.uniprot.org/uniprot/P21580 denotes A20
T3675 951-954 http://www.uniprot.org/uniprot/P21580 denotes A20
T3674 764-767 http://www.uniprot.org/uniprot/P21580 denotes A20
T3673 630-633 http://www.uniprot.org/uniprot/P21580 denotes A20
T3672 498-501 http://www.uniprot.org/uniprot/P21580 denotes A20
T3671 453-456 http://www.uniprot.org/uniprot/P21580 denotes A20
T3670 324-327 http://www.uniprot.org/uniprot/P21580 denotes A20
T3669 94-97 http://www.uniprot.org/uniprot/P21580 denotes A20
T3668 0-3 http://www.uniprot.org/uniprot/P21580 denotes A20
T3663 1371-1375 http://www.uniprot.org/uniprot/O15455 denotes TLR3
T3657 1407-1412 http://www.uniprot.org/uniprot/Q14653 denotes IRF-3
T3649 370-373 http://www.uniprot.org/uniprot/P01375 denotes TNF

UBERON-AE

Id Subject Object Predicate Lexical cue
T910 1897-1901 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T909 559-564 http://purl.obolibrary.org/obo/UBERON_0000062 denotes organ

GO-BP

Id Subject Object Predicate Lexical cue
T1164 2206-2228 http://purl.obolibrary.org/obo/GO_0045824 denotes innate immune response
T1163 2206-2228 http://purl.obolibrary.org/obo/GO_0045089 denotes innate immune response
T1162 2206-2228 http://purl.obolibrary.org/obo/GO_0002218 denotes innate immune response
T1161 2206-2228 http://purl.obolibrary.org/obo/GO_0045088 denotes innate immune response
T1160 2206-2228 http://purl.obolibrary.org/obo/GO_0002227 denotes innate immune response
T1159 2114-2122 http://purl.obolibrary.org/obo/GO_0048286 denotes alveolar
T1158 2206-2228 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune response
T1157 2071-2084 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune
T1156 2024-2044 http://purl.obolibrary.org/obo/GO_0032602 denotes chemokine production
T1155 1484-1499 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T1154 411-416 http://purl.obolibrary.org/obo/GO_0004908 denotes IL-1R
T1153 1161-1171 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T1152 1097-1107 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T1151 281-291 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T1150 168-183 http://purl.obolibrary.org/obo/GO_0016874 denotes ligase activity
T1149 158-183 http://purl.obolibrary.org/obo/GO_0034450 denotes ubiquitin ligase activity
T1148 158-183 http://purl.obolibrary.org/obo/GO_1904667 denotes ubiquitin ligase activity
T1147 158-183 http://purl.obolibrary.org/obo/GO_1904668 denotes ubiquitin ligase activity
T1146 158-183 http://purl.obolibrary.org/obo/GO_1990757 denotes ubiquitin ligase activity
T1145 158-183 http://purl.obolibrary.org/obo/GO_1904666 denotes ubiquitin ligase activity
T1144 158-183 http://purl.obolibrary.org/obo/GO_0050372 denotes ubiquitin ligase activity
T1143 155-157 http://purl.obolibrary.org/obo/GO_0061667 denotes E3
T1142 155-157 http://purl.obolibrary.org/obo/GO_0061666 denotes E3
T1141 155-157 http://purl.obolibrary.org/obo/GO_0061665 denotes E3
T1140 155-157 http://purl.obolibrary.org/obo/GO_0061664 denotes E3
T1139 155-157 http://purl.obolibrary.org/obo/GO_0061663 denotes E3
T1138 155-157 http://purl.obolibrary.org/obo/GO_0061662 denotes E3
T1137 155-157 http://purl.obolibrary.org/obo/GO_0061661 denotes E3
T1136 155-157 http://purl.obolibrary.org/obo/GO_0061660 denotes E3
T1135 155-157 http://purl.obolibrary.org/obo/GO_0061659 denotes E3
T1134 158-183 http://purl.obolibrary.org/obo/GO_0061630 denotes ubiquitin ligase activity
T1133 155-157 http://purl.obolibrary.org/obo/GO_0061630 denotes E3
T1132 155-157 http://purl.obolibrary.org/obo/GO_0019787 denotes E3
T1131 158-183 http://purl.obolibrary.org/obo/GO_0004842 denotes ubiquitin ligase activity
T1130 155-157 http://purl.obolibrary.org/obo/GO_0004842 denotes E3
T1114 1026-1038 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T1113 714-726 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T1112 565-577 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T1096 1776-1785 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T1095 1384-1393 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T1094 311-320 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T1088 2213-2228 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response

GO-MF

Id Subject Object Predicate Lexical cue
T1200 411-416 http://purl.obolibrary.org/obo/GO_0004908 denotes IL-1R
T1199 168-183 http://purl.obolibrary.org/obo/GO_0016874 denotes ligase activity
T1198 158-183 http://purl.obolibrary.org/obo/GO_0034450 denotes ubiquitin ligase activity
T1197 158-183 http://purl.obolibrary.org/obo/GO_1990757 denotes ubiquitin ligase activity
T1196 158-183 http://purl.obolibrary.org/obo/GO_0050372 denotes ubiquitin ligase activity
T1195 155-157 http://purl.obolibrary.org/obo/GO_0061667 denotes E3
T1194 155-157 http://purl.obolibrary.org/obo/GO_0061666 denotes E3
T1193 155-157 http://purl.obolibrary.org/obo/GO_0061665 denotes E3
T1192 155-157 http://purl.obolibrary.org/obo/GO_0061664 denotes E3
T1191 155-157 http://purl.obolibrary.org/obo/GO_0061663 denotes E3
T1190 155-157 http://purl.obolibrary.org/obo/GO_0061662 denotes E3
T1189 155-157 http://purl.obolibrary.org/obo/GO_0061661 denotes E3
T1188 155-157 http://purl.obolibrary.org/obo/GO_0061660 denotes E3
T1187 155-157 http://purl.obolibrary.org/obo/GO_0061659 denotes E3
T1186 158-183 http://purl.obolibrary.org/obo/GO_0061630 denotes ubiquitin ligase activity
T1185 155-157 http://purl.obolibrary.org/obo/GO_0061630 denotes E3
T1184 155-157 http://purl.obolibrary.org/obo/GO_0019787 denotes E3
T1183 158-183 http://purl.obolibrary.org/obo/GO_0004842 denotes ubiquitin ligase activity
T1182 155-157 http://purl.obolibrary.org/obo/GO_0004842 denotes E3
T1180 158-167 http://purl.obolibrary.org/obo/GO_0031386 denotes ubiquitin
T1179 10-19 http://purl.obolibrary.org/obo/GO_0031386 denotes ubiquitin

GO-CC

Id Subject Object Predicate Lexical cue
T1215 2273-2278 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1214 2085-2090 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1213 1636-1641 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1212 1539-1543 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T1211 1315-1319 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T1210 646-650 http://purl.obolibrary.org/obo/GO_0005623 denotes cell

sentences

Id Subject Object Predicate Lexical cue
T945 2166-2312 Sentence denotes These results suggest that boosting the innate immune response to IAV by targeting A20 activity in myeloid cells might have therapeutic potential.
T944 1940-2165 Sentence denotes Protection against IAV in A20myel-KO mice is associated with increased cytokine and chemokine production, augmented recruitment of innate immune cells such as neutophils and alveolar macrophages, and enhanced viral clearance.
T943 1802-1939 Sentence denotes Interestingly, A20myel-KO mice show enhanced survival and reduced morbidity in response to IAV lung infection compared to wild type mice.
T942 1525-1801 Sentence denotes Using myeloid cell specific A20 knockout mice (A20myel-KO) that were recently generated in our lab and primary cells derived of these mice, we here provide evidence that A20 is a crucial negative regulator of IAV-induced proinflammatory and antiviral signaling in macrophages.
T941 1424-1524 Sentence denotes However, the precise in vivo role of A20 in the response to viral infection remains to be clarified.
T940 1045-1423 Sentence denotes In contrast to its well established function in the regulation of proinflammatory responses, the role of A20 in the regulation of antiviral immune responses is less well described and limited to a number of in vitro studies using overexpression or silencing in specific cell lines, indicating that A20 may regulate RIG-I- and TLR3-induced signaling to NF-κB and IRF-3 [49]–[52].
T939 820-1044 Sentence denotes The relevance of these findings for human disease has recently been illustrated through the identification of polymorphisms in the A20 locus that are associated with several autoimmune diseases and chronic inflammation [45].
T938 597-819 Sentence denotes More recently, gene targeting of A20 in specific cell types was shown to be associated with autoimmunity and chronic inflammation [42]–[48], further illustrating that A20 is an important brake on the inflammatory response.
T937 423-596 Sentence denotes The anti-inflammatory role of A20 is clearly demonstrated by the fact that A20 deficient mice die early after birth due to severe multi-organ inflammation and cachexia [37].
T936 185-422 Sentence denotes Both catalytic and noncatalytic mechanisms were previously shown to be involved in the negative regulation of proinflammatory signaling by A20 in response to multiple receptors such as TNF receptor I [37]–[39], TLR4 [40], and IL-1R [41].
T935 79-184 Sentence denotes Interestingly, A20 also harbors atypical zinc finger dependent K48-specific E3 ubiquitin ligase activity.
T934 0-78 Sentence denotes A20 is an ubiquitin-editing enzyme belonging to the OTU-domain family of DUBs.
T45 0-78 Sentence denotes A20 is an ubiquitin-editing enzyme belonging to the OTU-domain family of DUBs.
T46 79-184 Sentence denotes Interestingly, A20 also harbors atypical zinc finger dependent K48-specific E3 ubiquitin ligase activity.
T47 185-422 Sentence denotes Both catalytic and noncatalytic mechanisms were previously shown to be involved in the negative regulation of proinflammatory signaling by A20 in response to multiple receptors such as TNF receptor I [37]–[39], TLR4 [40], and IL-1R [41].
T48 423-596 Sentence denotes The anti-inflammatory role of A20 is clearly demonstrated by the fact that A20 deficient mice die early after birth due to severe multi-organ inflammation and cachexia [37].
T49 597-819 Sentence denotes More recently, gene targeting of A20 in specific cell types was shown to be associated with autoimmunity and chronic inflammation [42]–[48], further illustrating that A20 is an important brake on the inflammatory response.
T50 820-1044 Sentence denotes The relevance of these findings for human disease has recently been illustrated through the identification of polymorphisms in the A20 locus that are associated with several autoimmune diseases and chronic inflammation [45].
T51 1045-1423 Sentence denotes In contrast to its well established function in the regulation of proinflammatory responses, the role of A20 in the regulation of antiviral immune responses is less well described and limited to a number of in vitro studies using overexpression or silencing in specific cell lines, indicating that A20 may regulate RIG-I- and TLR3-induced signaling to NF-κB and IRF-3 [49]–[52].
T52 1424-1524 Sentence denotes However, the precise in vivo role of A20 in the response to viral infection remains to be clarified.
T53 1525-1801 Sentence denotes Using myeloid cell specific A20 knockout mice (A20myel-KO) that were recently generated in our lab and primary cells derived of these mice, we here provide evidence that A20 is a crucial negative regulator of IAV-induced proinflammatory and antiviral signaling in macrophages.
T54 1802-1939 Sentence denotes Interestingly, A20myel-KO mice show enhanced survival and reduced morbidity in response to IAV lung infection compared to wild type mice.
T55 1940-2165 Sentence denotes Protection against IAV in A20myel-KO mice is associated with increased cytokine and chemokine production, augmented recruitment of innate immune cells such as neutophils and alveolar macrophages, and enhanced viral clearance.
T56 2166-2312 Sentence denotes These results suggest that boosting the innate immune response to IAV by targeting A20 activity in myeloid cells might have therapeutic potential.

ICD10

Id Subject Object Predicate Lexical cue
T1166 1484-1499 http://purl.bioontology.org/ontology/ICD10/B34.9 denotes viral infection
T1165 582-590 http://purl.bioontology.org/ontology/ICD10/R64 denotes cachexia

simple1

Id Subject Object Predicate Lexical cue
T1338 1407-1412 Protein denotes IRF-3
T1337 1371-1375 Protein denotes TLR3
T1336 1360-1365 Protein denotes RIG-I
T1335 411-416 Protein denotes IL-1R
T1334 396-400 Protein denotes TLR4
T1333 370-384 Protein denotes TNF receptor I

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T4149 1407-1412 Protein denotes IRF-3
T4148 1371-1375 Protein denotes TLR3
T4147 1360-1365 Protein denotes RIG-I
T4146 411-416 Protein denotes IL-1R
T4145 396-400 Protein denotes TLR4
T4144 370-384 Protein denotes TNF receptor I

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T3738 1407-1412 Protein denotes IRF-3
T3737 1371-1375 Protein denotes TLR3
T3736 1360-1365 Protein denotes RIG-I
T3735 411-416 Protein denotes IL-1R
T3734 396-400 Protein denotes TLR4
T3733 370-384 Protein denotes TNF receptor I

DLUT931

Id Subject Object Predicate Lexical cue
T3821 1351-1359 Regulation denotes regulate
T3806 1407-1412 Protein denotes IRF-3
T3805 1371-1375 Protein denotes TLR3
T3804 1360-1365 Protein denotes RIG-I
T3803 411-416 Protein denotes IL-1R
T3802 396-400 Protein denotes TLR4
T3801 370-384 Protein denotes TNF receptor I
R2970 T3804 T3821 themeOf RIG-I,regulate
R2972 T3806 T3821 causeOf IRF-3,regulate

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T4356 2024-2045 Gene_expression denotes chemokine production,
T4352 1977-2019 Binding denotes mice is associated with increased cytokine
T4344 612-656 Localization denotes gene targeting of A20 in specific cell types
T4333 0-3 Protein denotes A20
T4324 2114-2135 Entity denotes alveolar macrophages,
T4323 2078-2098 Entity denotes immune cells such as
T4319 1828-1832 Protein denotes mice
T4316 627-633 Protein denotes of A20
T4309 94-97 Protein denotes A20
T4308 73-77 Protein denotes DUBs
T4307 1531-1552 Entity denotes myeloid cell specific
T4304 142-154 Entity denotes K48-specific
T4302 1789-1800 Entity denotes macrophages
T4301 1343-1346 Protein denotes A20
T4295 168-174 Protein denotes ligase
T4294 1766-1775 Entity denotes antiviral
T4290 1360-1366 Protein denotes RIG-I-
T4289 1921-1938 Protein denotes to wild type mice
T4286 396-406 Protein denotes TLR4 [40],
T4284 2249-2252 Protein denotes A20
T4282 450-456 Protein denotes of A20
T4275 1977-1981 Protein denotes mice
T4274 1996-2019 Protein denotes with increased cytokine
T4271 48-55 Protein denotes the OTU
T4269 1407-1412 Protein denotes IRF-3
T4265 1531-1570 Protein denotes myeloid cell specific A20 knockout mice
T4262 120-124 Entity denotes zinc
T4257 612-616 Protein denotes gene
T4256 1147-1153 Protein denotes of A20
T4247 1172-1201 Entity denotes of antiviral immune responses
T4244 1553-1556 Protein denotes A20
T4237 343-389 Protein denotes multiple receptors such as TNF receptor I [37]
T4235 343-369 Protein denotes multiple receptors such as
T4234 2265-2278 Entity denotes myeloid cells
T4233 764-767 Protein denotes A20
T4225 7-62 Entity denotes an ubiquitin-editing enzyme belonging to the OTU-domain
T4224 2024-2033 Protein denotes chemokine
T4222 1371-1383 Protein denotes TLR3-induced
T4208 411-416 Protein denotes IL-1R
T4204 423-456 Entity denotes The anti-inflammatory role of A20
T4170 111-167 Protein denotes atypical zinc finger dependent K48-specific E3 ubiquitin
T4167 951-954 Protein denotes A20
T4164 498-516 Protein denotes A20 deficient mice
T4163 637-656 Entity denotes specific cell types
T4202 1397-1402 Protein denotes NF-κB
T4201 28-34 Protein denotes enzyme
T4200 324-327 Protein denotes A20
T4181 1695-1698 Protein denotes A20
T4173 1458-1464 Protein denotes of A20
T4172 498-501 Protein denotes A20
R3092 T4163 T4344 locationOf specific cell types,gene targeting of A20 in specific cell types
R3101 T4224 T4356 themeOf chemokine,"chemokine production,"
R3103 T4316 T4344 themeOf of A20,gene targeting of A20 in specific cell types
R3113 T4274 T4352 themeOf with increased cytokine,mice is associated with increased cytokine
R3114 T4275 T4352 themeOf mice,mice is associated with increased cytokine

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T3612 2085-2090 NNS denotes cells
T3611 2078-2084 JJ denotes immune
T3610 2071-2077 NN denotes innate
T3609 2068-2070 IN denotes of
T3608 2056-2067 NN denotes recruitment
T3607 2046-2055 JJ denotes augmented
T3606 2044-2045 , denotes ,
T3605 2034-2044 NN denotes production
T3604 2024-2033 NN denotes chemokine
T3603 2020-2023 CC denotes and
T3602 2011-2019 NN denotes cytokine
T3601 2001-2010 VBN denotes increased
T3600 1996-2000 IN denotes with
T3599 1985-1995 VBN denotes associated
T3598 1982-1984 VBZ denotes is
T3597 1977-1981 NNS denotes mice
T3596 1966-1976 NNP denotes A20myel-KO
T3595 1963-1965 IN denotes in
T3594 1959-1962 NNP denotes IAV
T3593 1951-1958 IN denotes against
T3592 1940-1950 NN denotes Protection
T3591 1938-1939 . denotes .
T3590 1934-1938 NNS denotes mice
T3589 1929-1933 NN denotes type
T3588 1924-1928 JJ denotes wild
T3587 1921-1923 TO denotes to
T3586 1912-1920 VBN denotes compared
T3585 1902-1911 NN denotes infection
T3584 1897-1901 NN denotes lung
T3583 1893-1896 NNP denotes IAV
T3582 1890-1892 TO denotes to
T3581 1881-1889 NN denotes response
T3580 1878-1880 IN denotes in
T3579 1868-1877 NN denotes morbidity
T3578 1860-1867 VBD denotes reduced
T3577 1856-1859 CC denotes and
T3576 1847-1855 NN denotes survival
T3575 1838-1846 JJ denotes enhanced
T3574 1833-1837 VBP denotes show
T3573 1828-1832 NNS denotes mice
T3572 1817-1827 JJ denotes A20myel-KO
T3571 1815-1816 , denotes ,
T3570 1802-1815 RB denotes Interestingly
T3569 1800-1801 . denotes .
T3568 1789-1800 NNS denotes macrophages
T3567 1786-1788 IN denotes in
T3566 1776-1785 VBG denotes signaling
T3565 1766-1775 JJ denotes antiviral
T3564 1762-1765 CC denotes and
T3563 1746-1761 JJ denotes proinflammatory
T3562 1734-1745 JJ denotes IAV-induced
T3561 1731-1733 IN denotes of
T3560 1721-1730 NN denotes regulator
T3559 1712-1720 JJ denotes negative
T3558 1704-1711 JJ denotes crucial
T3557 1702-1703 DT denotes a
T3556 1699-1701 VBZ denotes is
T3555 1695-1698 NNP denotes A20
T3554 1690-1694 IN denotes that
T3553 1681-1689 NN denotes evidence
T3552 1673-1680 VBP denotes provide
T3551 1668-1672 RB denotes here
T3550 1665-1667 PRP denotes we
T3549 1663-1664 , denotes ,
T3548 1659-1663 NNS denotes mice
T3547 1653-1658 DT denotes these
T3546 1650-1652 IN denotes of
T3545 1642-1649 VBN denotes derived
T3544 1636-1641 NNS denotes cells
T3543 1628-1635 JJ denotes primary
T3542 1624-1627 CC denotes and
T3541 1620-1623 NN denotes lab
T3490 1365-1366 : denotes -
T3489 1360-1365 NNP denotes RIG-I
T3488 1351-1359 VB denotes regulate
T3487 1347-1350 MD denotes may
T3486 1343-1346 NNP denotes A20
T3485 1338-1342 IN denotes that
T3484 1327-1337 VBG denotes indicating
T3483 1325-1326 , denotes ,
T3482 1320-1325 NNS denotes lines
T3481 1315-1319 NN denotes cell
T3480 1306-1314 JJ denotes specific
T3479 1303-1305 IN denotes in
T3478 1293-1302 VBG denotes silencing
T3477 1290-1292 CC denotes or
T3476 1275-1289 NN denotes overexpression
T3475 1269-1274 VBG denotes using
T3474 1261-1268 NNS denotes studies
T3473 1255-1260 NN denotes vitro
T3472 1252-1254 IN denotes in
T3471 1249-1251 IN denotes of
T3470 1242-1248 NN denotes number
T3469 1240-1241 DT denotes a
T3468 1237-1239 TO denotes to
T3467 1229-1236 VBN denotes limited
T3466 1225-1228 CC denotes and
T3465 1215-1224 VBN denotes described
T3464 1210-1214 RB denotes well
T3463 1205-1209 RBR denotes less
T3462 1202-1204 VBZ denotes is
T3461 1192-1201 NNS denotes responses
T3460 1185-1191 JJ denotes immune
T3459 1175-1184 JJ denotes antiviral
T3458 1172-1174 IN denotes of
T3457 1161-1171 NN denotes regulation
T3456 1157-1160 DT denotes the
T3455 1154-1156 IN denotes in
T3454 1150-1153 NNP denotes A20
T3453 1147-1149 IN denotes of
T3452 1142-1146 NN denotes role
T3451 1138-1141 DT denotes the
T3450 1136-1137 , denotes ,
T3449 1127-1136 NNS denotes responses
T3448 1111-1126 JJ denotes proinflammatory
T3447 1108-1110 IN denotes of
T3446 1097-1107 NN denotes regulation
T3445 1093-1096 DT denotes the
T3444 1090-1092 IN denotes in
T3443 1081-1089 NN denotes function
T3442 1069-1080 VBN denotes established
T3441 1064-1068 RB denotes well
T3440 1060-1063 PRP$ denotes its
T3439 1057-1059 TO denotes to
T3438 1048-1056 NN denotes contrast
T3437 1045-1047 IN denotes In
T3436 1043-1044 . denotes .
T3435 1042-1043 NNP denotes ]
T3434 1040-1042 CD denotes 45
T3433 1039-1040 NNP denotes [
T3432 1026-1038 NN denotes inflammation
T3431 1018-1025 JJ denotes chronic
T3430 1014-1017 CC denotes and
T3429 1005-1013 NNS denotes diseases
T3428 994-1004 JJ denotes autoimmune
T3427 986-993 JJ denotes several
T3426 981-985 IN denotes with
T3425 970-980 VBN denotes associated
T3424 966-969 VBP denotes are
T3423 961-965 WDT denotes that
T3422 955-960 NN denotes locus
T3421 951-954 NNP denotes A20
T3420 947-950 DT denotes the
T3419 944-946 IN denotes in
T3418 930-943 NNS denotes polymorphisms
T3417 927-929 IN denotes of
T3416 912-926 NN denotes identification
T3415 908-911 DT denotes the
T3414 900-907 IN denotes through
T3413 888-899 VBN denotes illustrated
T3412 883-887 VBN denotes been
T3411 874-882 RB denotes recently
T3410 870-873 VBZ denotes has
T3409 862-869 NN denotes disease
T3408 856-861 JJ denotes human
T3407 852-855 IN denotes for
T3406 843-851 NNS denotes findings
T3405 837-842 DT denotes these
T3404 834-836 IN denotes of
T3403 824-833 NN denotes relevance
T3402 820-823 DT denotes The
T3401 818-819 . denotes .
T3400 810-818 NN denotes response
T3399 797-809 JJ denotes inflammatory
T3398 793-796 DT denotes the
T3397 790-792 IN denotes on
T3396 784-789 NN denotes brake
T3395 774-783 JJ denotes important
T3394 771-773 DT denotes an
T3393 768-770 VBZ denotes is
T3392 764-767 NNP denotes A20
T3391 759-763 IN denotes that
T3390 746-758 VBG denotes illustrating
T3389 738-745 JJ denotes further
T3388 736-737 , denotes ,
T3387 735-736 NNP denotes ]
T3386 733-735 CD denotes 48
T3385 732-733 NNP denotes [
T3384 730-731 NNP denotes ]
T3383 728-730 CD denotes 42
T3382 727-728 NNP denotes [
T3381 714-726 NN denotes inflammation
T3380 706-713 JJ denotes chronic
T3379 702-705 CC denotes and
T3378 689-701 NN denotes autoimmunity
T3377 684-688 IN denotes with
T3376 673-683 VBN denotes associated
T3375 670-672 VB denotes be
T3374 667-669 TO denotes to
T3373 661-666 VBN denotes shown
T3372 657-660 VBD denotes was
T3371 651-656 NNS denotes types
T3370 646-650 NN denotes cell
T3369 637-645 JJ denotes specific
T3368 634-636 IN denotes in
T3367 630-633 NNP denotes A20
T3366 627-629 IN denotes of
T3365 617-626 VBG denotes targeting
T3364 612-616 NN denotes gene
T3363 610-611 , denotes ,
T3362 602-610 RB denotes recently
T3361 597-601 RBR denotes More
T3360 595-596 . denotes .
T3359 594-595 NNP denotes ]
T3358 592-594 CD denotes 37
T3357 591-592 NNP denotes [
T3356 582-590 NN denotes cachexia
T3355 578-581 CC denotes and
T3354 565-577 NN denotes inflammation
T3353 553-564 JJ denotes multi-organ
T3352 546-552 JJ denotes severe
T3351 543-545 TO denotes to
T3350 539-542 JJ denotes due
T3349 533-538 NN denotes birth
T3348 527-532 IN denotes after
T3347 521-526 RB denotes early
T3346 517-520 VBP denotes die
T3345 512-516 NNS denotes mice
T3344 502-511 JJ denotes deficient
T3343 498-501 CD denotes A20
T3342 493-497 IN denotes that
T3341 488-492 NN denotes fact
T3340 484-487 DT denotes the
T3339 481-483 IN denotes by
T3338 468-480 VBN denotes demonstrated
T3337 460-467 RB denotes clearly
T3336 457-459 VBZ denotes is
T3335 453-456 NNP denotes A20
T3334 450-452 IN denotes of
T3333 445-449 NN denotes role
T3332 427-444 JJ denotes anti-inflammatory
T3331 423-426 DT denotes The
T3330 421-422 . denotes .
T3329 420-421 NNP denotes ]
T3328 418-420 CD denotes 41
T3327 417-418 NNP denotes [
T3326 411-416 NNP denotes IL-1R
T3325 407-410 CC denotes and
T3324 405-406 , denotes ,
T3323 404-405 NNP denotes ]
T3322 402-404 CD denotes 40
T3321 401-402 NNP denotes [
T3320 396-400 CD denotes TLR4
T3319 394-395 , denotes ,
T3318 393-394 NNP denotes ]
T3317 391-393 CD denotes 39
T3316 390-391 NNP denotes [
T3315 388-389 NNP denotes ]
T3314 386-388 CD denotes 37
T3313 385-386 VBP denotes [
T3312 383-384 PRP denotes I
T3311 374-382 NN denotes receptor
T3310 370-373 NNP denotes TNF
T3309 367-369 IN denotes as
T3308 362-366 JJ denotes such
T3307 352-361 NNS denotes receptors
T3306 343-351 JJ denotes multiple
T3305 340-342 TO denotes to
T3304 331-339 NN denotes response
T3303 328-330 IN denotes in
T3302 324-327 NNP denotes A20
T3301 321-323 IN denotes by
T3300 311-320 VBG denotes signaling
T3299 295-310 JJ denotes proinflammatory
T3298 292-294 IN denotes of
T3297 281-291 NN denotes regulation
T3296 272-280 JJ denotes negative
T3295 268-271 DT denotes the
T3294 265-267 IN denotes in
T3293 256-264 VBN denotes involved
T3292 253-255 VB denotes be
T3291 250-252 TO denotes to
T3290 244-249 VBN denotes shown
T3289 233-243 RB denotes previously
T3288 228-232 VBD denotes were
T3287 217-227 NNS denotes mechanisms
T3286 204-216 JJ denotes noncatalytic
T3285 200-203 CC denotes and
T3284 190-199 JJ denotes catalytic
T3283 185-189 DT denotes Both
T3282 183-184 . denotes .
T3281 175-183 NN denotes activity
T3280 168-174 NN denotes ligase
T3279 158-167 NN denotes ubiquitin
T3278 155-157 NN denotes E3
T3277 142-154 JJ denotes K48-specific
T3276 132-141 JJ denotes dependent
T3275 125-131 NN denotes finger
T3540 1616-1619 PRP$ denotes our
T3539 1613-1615 IN denotes in
T3538 1603-1612 VBN denotes generated
T3537 1594-1602 RB denotes recently
T3536 1589-1593 VBD denotes were
T3535 1584-1588 WDT denotes that
T3534 1582-1583 -RRB- denotes )
T3533 1572-1582 JJ denotes A20myel-KO
T3532 1571-1572 -LRB- denotes (
T3531 1566-1570 NNS denotes mice
T3530 1557-1565 NN denotes knockout
T3529 1553-1556 NNP denotes A20
T3528 1544-1552 JJ denotes specific
T3527 1539-1543 NN denotes cell
T3526 1531-1538 JJ denotes myeloid
T3525 1525-1530 VBG denotes Using
T3524 1523-1524 . denotes .
T3523 1514-1523 VBN denotes clarified
T3522 1511-1513 VB denotes be
T3521 1508-1510 TO denotes to
T3520 1500-1507 VBZ denotes remains
T3519 1490-1499 NN denotes infection
T3518 1484-1489 JJ denotes viral
T3517 1481-1483 TO denotes to
T3516 1472-1480 NN denotes response
T3515 1468-1471 DT denotes the
T3514 1465-1467 IN denotes in
T3513 1461-1464 NNP denotes A20
T3512 1458-1460 IN denotes of
T3511 1453-1457 NN denotes role
T3510 1448-1452 NN denotes vivo
T3509 1445-1447 IN denotes in
T3508 1437-1444 JJ denotes precise
T3507 1433-1436 DT denotes the
T3506 1431-1432 , denotes ,
T3505 1424-1431 RB denotes However
T3504 1422-1423 . denotes .
T3503 1421-1422 NNP denotes ]
T3502 1419-1421 CD denotes 52
T3501 1418-1419 NNP denotes [
T3500 1416-1417 NNP denotes ]
T3499 1414-1416 CD denotes 49
T3498 1413-1414 NNP denotes [
T3497 1407-1412 NNP denotes IRF-3
T3496 1403-1406 CC denotes and
T3495 1397-1402 NNP denotes NF-κB
T3494 1394-1396 TO denotes to
T3493 1384-1393 VBG denotes signaling
T3492 1371-1383 JJ denotes TLR3-induced
T3491 1367-1370 CC denotes and
T3274 120-124 NN denotes zinc
T3273 111-119 JJ denotes atypical
T3272 103-110 VBZ denotes harbors
T3271 98-102 RB denotes also
T3270 94-97 NNP denotes A20
T3269 92-93 , denotes ,
T3268 79-92 RB denotes Interestingly
T3267 77-78 . denotes .
T3266 73-77 NNS denotes DUBs
T3265 70-72 IN denotes of
T3264 63-69 NN denotes family
T3263 52-62 NNP denotes OTU-domain
T3262 48-51 DT denotes the
T3261 45-47 TO denotes to
T3260 35-44 VBG denotes belonging
T3259 28-34 NN denotes enzyme
T3258 10-27 JJ denotes ubiquitin-editing
T3257 7-9 DT denotes an
T3256 4-6 VBZ denotes is
T3255 0-3 CD denotes A20
T3647 2311-2312 . denotes .
T3646 2302-2311 NN denotes potential
T3645 2290-2301 JJ denotes therapeutic
T3644 2285-2289 VB denotes have
T3643 2279-2284 MD denotes might
T3642 2273-2278 NNS denotes cells
T3641 2265-2272 JJ denotes myeloid
T3640 2262-2264 IN denotes in
T3639 2253-2261 NN denotes activity
T3638 2249-2252 JJ denotes A20
T3637 2239-2248 VBG denotes targeting
T3636 2236-2238 IN denotes by
T3635 2232-2235 NNP denotes IAV
T3634 2229-2231 TO denotes to
T3633 2220-2228 NN denotes response
T3632 2213-2219 JJ denotes immune
T3631 2206-2212 NN denotes innate
T3630 2202-2205 DT denotes the
T3629 2193-2201 VBG denotes boosting
T3628 2188-2192 IN denotes that
T3627 2180-2187 VBP denotes suggest
T3626 2172-2179 NNS denotes results
T3625 2166-2171 DT denotes These
T3624 2164-2165 . denotes .
T3623 2155-2164 NN denotes clearance
T3622 2149-2154 JJ denotes viral
T3621 2140-2148 JJ denotes enhanced
T3620 2136-2139 CC denotes and
T3619 2134-2135 , denotes ,
T3618 2123-2134 NNS denotes macrophages
T3617 2114-2122 JJ denotes alveolar
T3616 2110-2113 CC denotes and
T3615 2099-2109 NNS denotes neutophils
T3614 2096-2098 IN denotes as
T3613 2091-2095 JJ denotes such
R2496 T3255 T3256 nsubj A20,is
R2497 T3256 T3256 ROOT is,is
R2498 T3257 T3259 det an,enzyme
R2499 T3258 T3259 amod ubiquitin-editing,enzyme
R2501 T3259 T3256 attr enzyme,is
R2502 T3260 T3259 acl belonging,enzyme
R2505 T3261 T3260 prep to,belonging
R2506 T3262 T3264 det the,family
R2508 T3263 T3264 compound OTU-domain,family
R2509 T3264 T3261 pobj family,to
R2510 T3265 T3264 prep of,family
R2512 T3266 T3265 pobj DUBs,of
R2513 T3267 T3256 punct .,is
R2514 T3268 T3272 advmod Interestingly,harbors
R2516 T3269 T3272 punct ",",harbors
R2518 T3270 T3272 nsubj A20,harbors
R2519 T3271 T3272 advmod also,harbors
R2520 T3272 T3272 ROOT harbors,harbors
R2522 T3273 T3275 amod atypical,finger
R2523 T3274 T3275 compound zinc,finger
R2524 T3275 T3281 nmod finger,activity
R2526 T3276 T3281 amod dependent,activity
R2527 T3277 T3281 amod K48-specific,activity
R2528 T3278 T3281 nmod E3,activity
R2530 T3279 T3281 compound ubiquitin,activity
R2531 T3280 T3281 compound ligase,activity
R2532 T3281 T3272 dobj activity,harbors
R2534 T3282 T3272 punct .,harbors
R2535 T3283 T3287 det Both,mechanisms
R2536 T3284 T3287 amod catalytic,mechanisms
R2537 T3285 T3284 cc and,catalytic
R2538 T3286 T3284 conj noncatalytic,catalytic
R2539 T3287 T3290 nsubjpass mechanisms,shown
R2541 T3288 T3290 auxpass were,shown
R2542 T3289 T3290 advmod previously,shown
R2543 T3290 T3290 ROOT shown,shown
R2545 T3291 T3293 aux to,involved
R2546 T3292 T3293 auxpass be,involved
R2548 T3293 T3290 xcomp involved,shown
R2549 T3294 T3293 prep in,involved
R2550 T3295 T3297 det the,regulation
R2551 T3296 T3297 amod negative,regulation
R2553 T3297 T3294 pobj regulation,in
R2554 T3298 T3297 prep of,regulation
R2556 T3299 T3298 pobj proinflammatory,of
R2557 T3300 T3297 acl signaling,regulation
R2558 T3301 T3300 prep by,signaling
R2560 T3302 T3301 pobj A20,by
R2561 T3303 T3300 prep in,signaling
R2562 T3304 T3303 pobj response,in
R2564 T3305 T3304 prep to,response
R2565 T3306 T3307 amod multiple,receptors
R2566 T3307 T3305 pobj receptors,to
R2568 T3308 T3309 amod such,as
R2569 T3309 T3307 prep as,receptors
R2570 T3310 T3311 compound TNF,receptor
R2572 T3311 T3309 pobj receptor,as
R2573 T3312 T3313 nsubj I,[
R2574 T3313 T3315 nmod [,]
R2576 T3314 T3315 nummod 37,]
R2577 T3315 T3315 ROOT ],]
R2579 T3316 T3315 appos [,]
R2580 T3317 T3318 nummod 39,]
R2649 T3364 T3365 compound gene,targeting
R2650 T3365 T3365 ROOT targeting,targeting
R2651 T3366 T3365 prep of,targeting
R2652 T3367 T3366 pobj A20,of
R2653 T3421 T3422 compound A20,locus
R2654 T3368 T3365 prep in,targeting
R2655 T3369 T3371 amod specific,types
R2656 T3370 T3371 compound cell,types
R2657 T3422 T3419 pobj locus,in
R2658 T3371 T3368 pobj types,in
R2659 T3372 T3373 auxpass was,shown
R2660 T3373 T3365 conj shown,targeting
R2661 T3423 T3425 nsubjpass that,associated
R2662 T3374 T3376 aux to,associated
R2663 T3375 T3376 auxpass be,associated
R2664 T3424 T3425 auxpass are,associated
R2665 T3376 T3373 xcomp associated,shown
R2666 T3377 T3376 prep with,associated
R2667 T3378 T3384 nmod autoimmunity,]
R2668 T3425 T3416 relcl associated,identification
R2669 T3379 T3378 cc and,autoimmunity
R2670 T3380 T3381 amod chronic,inflammation
R2671 T3381 T3378 conj inflammation,autoimmunity
R2672 T3426 T3425 prep with,associated
R2673 T3382 T3378 conj [,autoimmunity
R2674 T3383 T3384 nummod 42,]
R2675 T3384 T3377 pobj ],with
R2676 T3427 T3429 amod several,diseases
R2677 T3385 T3384 appos [,]
R2678 T3386 T3387 nummod 48,]
R2679 T3387 T3384 conj ],]
R2680 T3428 T3429 amod autoimmune,diseases
R2681 T3388 T3373 punct ",",shown
R2682 T3389 T3390 advmod further,illustrating
R2683 T3390 T3373 advcl illustrating,shown
R2684 T3429 T3426 pobj diseases,with
R2685 T3391 T3393 mark that,is
R2686 T3392 T3393 nsubj A20,is
R2687 T3393 T3390 ccomp is,illustrating
R2688 T3394 T3396 det an,brake
R2689 T3395 T3396 amod important,brake
R2690 T3396 T3393 attr brake,is
R2691 T3430 T3429 cc and,diseases
R2692 T3431 T3432 amod chronic,inflammation
R2694 T3432 T3429 conj inflammation,diseases
R2698 T3433 T3435 nmod [,]
R2702 T3434 T3435 nummod 45,]
R2705 T3435 T3432 appos ],inflammation
R2709 T3436 T3413 punct .,illustrated
R2713 T3437 T3462 prep In,is
R2717 T3438 T3437 pobj contrast,In
R2721 T3439 T3438 prep to,contrast
R2723 T3440 T3443 poss its,function
R2724 T3441 T3442 advmod well,established
R2725 T3442 T3443 amod established,function
R2726 T3516 T3514 pobj response,in
R2727 T3443 T3439 pobj function,to
R2728 T3517 T3516 prep to,response
R2729 T3518 T3519 amod viral,infection
R2730 T3519 T3517 pobj infection,to
R2731 T3444 T3443 prep in,function
R2732 T3520 T3520 ROOT remains,remains
R2733 T3521 T3523 aux to,clarified
R2734 T3445 T3446 det the,regulation
R2735 T3522 T3523 auxpass be,clarified
R2736 T3523 T3520 xcomp clarified,remains
R2737 T3524 T3520 punct .,remains
R2738 T3525 T3552 advcl Using,provide
R2739 T3526 T3527 amod myeloid,cell
R2740 T3446 T3444 pobj regulation,in
R2741 T3527 T3531 nmod cell,mice
R2742 T3528 T3531 amod specific,mice
R2743 T3529 T3531 compound A20,mice
R2744 T3530 T3531 compound knockout,mice
R2745 T3447 T3446 prep of,regulation
R2746 T3531 T3525 dobj mice,Using
R2747 T3532 T3531 punct (,mice
R2748 T3533 T3531 appos A20myel-KO,mice
R2749 T3448 T3449 amod proinflammatory,responses
R2750 T3534 T3531 punct ),mice
R2751 T3535 T3538 nsubjpass that,generated
R2752 T3449 T3447 pobj responses,of
R2753 T3536 T3538 auxpass were,generated
R2754 T3537 T3538 advmod recently,generated
R2755 T3538 T3525 relcl generated,Using
R2756 T3450 T3443 punct ",",function
R2757 T3539 T3538 prep in,generated
R2758 T3540 T3541 poss our,lab
R2759 T3541 T3539 pobj lab,in
R2760 T3451 T3452 det the,role
R2761 T3542 T3541 cc and,lab
R2762 T3543 T3544 amod primary,cells
R2763 T3544 T3541 conj cells,lab
R2764 T3545 T3544 acl derived,cells
R2765 T3452 T3462 nsubj role,is
R2766 T3546 T3545 prep of,derived
R2767 T3547 T3548 det these,mice
R2768 T3548 T3546 pobj mice,of
R2769 T3453 T3452 prep of,role
R2770 T3549 T3552 punct ",",provide
R2771 T3550 T3552 nsubj we,provide
R2772 T3454 T3453 pobj A20,of
R2773 T3551 T3552 advmod here,provide
R2774 T3552 T3552 ROOT provide,provide
R2775 T3553 T3552 dobj evidence,provide
R2776 T3455 T3452 prep in,role
R2777 T3554 T3556 mark that,is
R2778 T3555 T3556 nsubj A20,is
R2779 T3556 T3553 acl is,evidence
R2780 T3557 T3560 det a,regulator
R2781 T3456 T3457 det the,regulation
R2782 T3558 T3560 amod crucial,regulator
R2783 T3559 T3560 amod negative,regulator
R2784 T3560 T3556 attr regulator,is
R2785 T3457 T3455 pobj regulation,in
R2786 T3561 T3560 prep of,regulator
R2787 T3562 T3566 amod IAV-induced,signaling
R2788 T3563 T3566 amod proinflammatory,signaling
R2789 T3564 T3563 cc and,proinflammatory
R2790 T3565 T3563 conj antiviral,proinflammatory
R2791 T3566 T3561 pobj signaling,of
R2792 T3458 T3457 prep of,regulation
R2793 T3567 T3566 prep in,signaling
R2794 T3568 T3567 pobj macrophages,in
R2795 T3569 T3552 punct .,provide
R2796 T3570 T3574 advmod Interestingly,show
R2797 T3459 T3461 amod antiviral,responses
R2798 T3571 T3574 punct ",",show
R2799 T3572 T3573 amod A20myel-KO,mice
R2800 T3460 T3461 amod immune,responses
R2801 T3573 T3574 nsubj mice,show
R2802 T3574 T3574 ROOT show,show
R2803 T3575 T3576 amod enhanced,survival
R2804 T3461 T3458 pobj responses,of
R2805 T3576 T3574 dobj survival,show
R2806 T3577 T3574 cc and,show
R2807 T3578 T3574 conj reduced,show
R2808 T3462 T3462 ROOT is,is
R2809 T3463 T3465 advmod less,described
R2810 T3579 T3578 dobj morbidity,reduced
R2811 T3580 T3578 prep in,reduced
R2812 T3464 T3465 advmod well,described
R2813 T3581 T3580 pobj response,in
R2814 T3582 T3581 prep to,response
R2815 T3583 T3585 compound IAV,infection
R2816 T3465 T3462 acomp described,is
R2817 T3584 T3585 compound lung,infection
R2818 T3585 T3582 pobj infection,to
R2819 T3586 T3578 prep compared,reduced
R2820 T3466 T3465 cc and,described
R2821 T3587 T3586 prep to,compared
R2822 T3588 T3590 amod wild,mice
R2823 T3467 T3465 conj limited,described
R2824 T3589 T3590 compound type,mice
R2825 T3590 T3587 pobj mice,to
R2826 T3591 T3574 punct .,show
R2827 T3468 T3467 prep to,limited
R2828 T3592 T3599 nsubjpass Protection,associated
R2829 T3593 T3592 prep against,Protection
R2830 T3469 T3470 det a,number
R2831 T3594 T3593 pobj IAV,against
R2832 T3595 T3594 prep in,IAV
R2833 T3596 T3597 compound A20myel-KO,mice
R2834 T3597 T3595 pobj mice,in
R2835 T3470 T3468 pobj number,to
R2836 T3598 T3599 auxpass is,associated
R2837 T3599 T3599 ROOT associated,associated
R2838 T3600 T3599 prep with,associated
R2839 T3601 T3602 amod increased,cytokine
R2840 T3602 T3600 pobj cytokine,with
R2841 T3603 T3602 cc and,cytokine
R2842 T3471 T3470 prep of,number
R2843 T3604 T3605 compound chemokine,production
R2844 T3605 T3602 conj production,cytokine
R2845 T3606 T3605 punct ",",production
R2846 T3472 T3470 prep in,number
R2847 T3607 T3608 amod augmented,recruitment
R2848 T3608 T3602 conj recruitment,cytokine
R2849 T3609 T3608 prep of,recruitment
R2850 T3473 T3474 amod vitro,studies
R2851 T3610 T3612 amod innate,cells
R2852 T3611 T3612 amod immune,cells
R2853 T3474 T3472 pobj studies,in
R2854 T3612 T3609 pobj cells,of
R2855 T3475 T3467 advcl using,limited
R2856 T3476 T3475 dobj overexpression,using
R2857 T3613 T3614 amod such,as
R2858 T3614 T3612 prep as,cells
R2859 T3477 T3475 cc or,using
R2860 T3615 T3614 pobj neutophils,as
R2861 T3616 T3615 cc and,neutophils
R2862 T3617 T3618 amod alveolar,macrophages
R2863 T3478 T3475 conj silencing,using
R2864 T3618 T3615 conj macrophages,neutophils
R2865 T3619 T3618 punct ",",macrophages
R2866 T3620 T3618 cc and,macrophages
R2867 T3479 T3478 prep in,silencing
R2868 T3621 T3623 amod enhanced,clearance
R2869 T3622 T3623 amod viral,clearance
R2870 T3623 T3618 conj clearance,macrophages
R2871 T3480 T3482 amod specific,lines
R2872 T3624 T3599 punct .,associated
R2873 T3625 T3626 det These,results
R2874 T3481 T3482 compound cell,lines
R2875 T3626 T3627 nsubj results,suggest
R2876 T3627 T3627 ROOT suggest,suggest
R2877 T3628 T3644 mark that,have
R2878 T3482 T3479 pobj lines,in
R2879 T3629 T3644 csubj boosting,have
R2880 T3630 T3633 det the,response
R2881 T3483 T3462 punct ",",is
R2882 T3631 T3633 amod innate,response
R2883 T3632 T3633 amod immune,response
R2884 T3633 T3629 dobj response,boosting
R2885 T3484 T3462 advcl indicating,is
R2886 T3634 T3633 prep to,response
R2887 T3635 T3634 pobj IAV,to
R2888 T3636 T3629 prep by,boosting
R2889 T3637 T3636 pcomp targeting,by
R2890 T3638 T3639 amod A20,activity
R2891 T3639 T3637 dobj activity,targeting
R2892 T3485 T3488 mark that,regulate
R2893 T3640 T3637 prep in,targeting
R2894 T3641 T3642 amod myeloid,cells
R2895 T3642 T3640 pobj cells,in
R2896 T3486 T3488 nsubj A20,regulate
R2897 T3643 T3644 aux might,have
R2898 T3644 T3627 ccomp have,suggest
R2899 T3487 T3488 aux may,regulate
R2900 T3645 T3646 amod therapeutic,potential
R2901 T3646 T3644 dobj potential,have
R2902 T3647 T3627 punct .,suggest
R2903 T3488 T3484 ccomp regulate,indicating
R2904 T3489 T3488 dobj RIG-I,regulate
R2905 T3490 T3489 punct -,RIG-I
R2906 T3491 T3489 cc and,RIG-I
R2907 T3492 T3493 amod TLR3-induced,signaling
R2908 T3493 T3488 dobj signaling,regulate
R2909 T3494 T3501 prep to,[
R2910 T3495 T3494 pobj NF-κB,to
R2911 T3496 T3495 cc and,NF-κB
R2912 T3497 T3498 compound IRF-3,[
R2913 T3498 T3495 conj [,NF-κB
R2914 T3499 T3500 nummod 49,]
R2915 T3500 T3501 nmod ],[
R2916 T3501 T3488 xcomp [,regulate
R2917 T3502 T3503 nummod 52,]
R2918 T3503 T3501 dobj ],[
R2919 T3504 T3462 punct .,is
R2920 T3505 T3520 advmod However,remains
R2921 T3506 T3520 punct ",",remains
R2922 T3507 T3508 det the,precise
R2923 T3508 T3520 nsubj precise,remains
R2924 T3509 T3508 prep in,precise
R2925 T3510 T3511 compound vivo,role
R2926 T3511 T3509 pobj role,in
R2927 T3512 T3511 prep of,role
R2928 T3513 T3512 pobj A20,of
R2929 T3514 T3511 prep in,role
R2930 T3515 T3516 det the,response
R2599 T3329 T3323 conj ],]
R2600 T3330 T3290 punct .,shown
R2601 T3331 T3333 det The,role
R2603 T3332 T3333 amod anti-inflammatory,role
R2615 T3340 T3341 det the,fact
R2582 T3318 T3315 conj ],]
R2584 T3319 T3318 punct ",",]
R2585 T3320 T3323 nummod TLR4,]
R2586 T3321 T3323 nmod [,]
R2589 T3322 T3323 nummod 40,]
R2590 T3323 T3318 conj ],]
R2592 T3324 T3323 punct ",",]
R2593 T3325 T3323 cc and,]
R2595 T3326 T3327 compound IL-1R,[
R2596 T3327 T3323 conj [,]
R2597 T3328 T3329 nummod 41,]
R2604 T3333 T3338 nsubjpass role,demonstrated
R2606 T3334 T3333 prep of,role
R2607 T3335 T3334 pobj A20,of
R2608 T3336 T3338 auxpass is,demonstrated
R2609 T3337 T3338 advmod clearly,demonstrated
R2611 T3338 T3338 ROOT demonstrated,demonstrated
R2612 T3339 T3338 agent by,demonstrated
R2619 T3341 T3339 pobj fact,by
R2620 T3342 T3346 mark that,die
R2622 T3343 T3345 nummod A20,mice
R2623 T3344 T3345 amod deficient,mice
R2625 T3345 T3346 nsubj mice,die
R2626 T3346 T3341 acl die,fact
R2627 T3347 T3348 advmod early,after
R2629 T3348 T3346 prep after,die
R2630 T3349 T3348 pobj birth,after
R2631 T3350 T3341 amod due,fact
R2633 T3351 T3350 prep to,due
R2634 T3352 T3354 amod severe,inflammation
R2635 T3353 T3354 amod multi-organ,inflammation
R2636 T3354 T3351 pobj inflammation,to
R2637 T3355 T3354 cc and,inflammation
R2639 T3356 T3354 conj cachexia,inflammation
R2640 T3357 T3359 nmod [,]
R2641 T3358 T3359 nummod 37,]
R2643 T3359 T3356 appos ],cachexia
R2644 T3360 T3338 punct .,demonstrated
R2645 T3361 T3362 advmod More,recently
R2646 T3362 T3365 advmod recently,targeting
R2647 T3363 T3365 punct ",",targeting
R2642 T3419 T3418 prep in,polymorphisms
R2648 T3420 T3422 det the,locus
R2693 T3397 T3396 prep on,brake
R2695 T3398 T3400 det the,response
R2696 T3399 T3400 amod inflammatory,response
R2697 T3400 T3397 pobj response,on
R2699 T3401 T3373 punct .,shown
R2700 T3402 T3403 det The,relevance
R2701 T3403 T3413 nsubjpass relevance,illustrated
R2703 T3404 T3403 prep of,relevance
R2704 T3405 T3406 det these,findings
R2706 T3406 T3404 pobj findings,of
R2707 T3407 T3403 prep for,relevance
R2708 T3408 T3409 amod human,disease
R2710 T3409 T3407 pobj disease,for
R2711 T3410 T3413 aux has,illustrated
R2712 T3411 T3413 advmod recently,illustrated
R2714 T3412 T3413 auxpass been,illustrated
R2715 T3413 T3413 ROOT illustrated,illustrated
R2716 T3414 T3413 prep through,illustrated
R2718 T3415 T3416 det the,identification
R2719 T3416 T3414 pobj identification,through
R2720 T3417 T3416 prep of,identification
R2722 T3418 T3417 pobj polymorphisms,of

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T3988 2249-2252 Protein denotes A20
T3987 1695-1698 Protein denotes A20
T3986 1461-1464 Protein denotes A20
T3985 1407-1412 Protein denotes IRF-3
T3984 1397-1402 Protein denotes NF-κB
T3983 1371-1375 Protein denotes TLR3
T3982 1343-1346 Protein denotes A20
T3981 1150-1153 Protein denotes A20
T3980 951-960 Protein denotes A20 locus
T3979 764-767 Protein denotes A20
T3978 630-633 Protein denotes A20
T3977 453-456 Protein denotes A20
T3976 370-384 Protein denotes TNF receptor I
T3975 324-327 Protein denotes A20
T3974 158-174 Protein denotes ubiquitin ligase
T3973 155-157 Protein denotes E3
T3972 94-97 Protein denotes A20
T3971 52-69 Protein denotes OTU-domain family
T3970 10-19 Protein denotes ubiquitin
T3969 0-3 Protein denotes A20

testone

Id Subject Object Predicate Lexical cue
T783 502-511 Negative_regulation denotes deficient
T771 1407-1412 Protein denotes IRF-3
T770 1371-1375 Protein denotes TLR3
T769 1360-1365 Protein denotes RIG-I
T768 411-416 Protein denotes IL-1R
T767 396-400 Protein denotes TLR4
T766 370-384 Protein denotes TNF receptor I