PMC:329117 / 20648-21370 JSONTXT

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    craft-sa-dev

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    {"project":"craft-ca-core-ex-dev","denotations":[{"id":"T5657","span":{"begin":4,"end":8},"obj":"SO_EXT:cDNA"},{"id":"T5658","span":{"begin":60,"end":69},"obj":"GO:0007608"},{"id":"T5659","span":{"begin":60,"end":79},"obj":"GO_EXT:0004984"},{"id":"T5660","span":{"begin":93,"end":113},"obj":"GO:0000380"},{"id":"T5661","span":{"begin":123,"end":144},"obj":"SO_EXT:0000445"},{"id":"T5662","span":{"begin":128,"end":138},"obj":"GO:0006412"},{"id":"T5663","span":{"begin":198,"end":202},"obj":"SO_EXT:cDNA"},{"id":"T5664","span":{"begin":207,"end":214},"obj":"SO_EXT:0001026"},{"id":"T5665","span":{"begin":215,"end":224},"obj":"SO_EXT:biological_sequence"},{"id":"T5666","span":{"begin":257,"end":263},"obj":"GO:0008380"},{"id":"T5667","span":{"begin":257,"end":269},"obj":"SO_EXT:alternative_splice_variant"},{"id":"T5668","span":{"begin":294,"end":299},"obj":"SO_EXT:0000704"},{"id":"T5669","span":{"begin":350,"end":368},"obj":"GO:0000380"},{"id":"T5670","span":{"begin":396,"end":401},"obj":"SO_EXT:cDNA"},{"id":"T5671","span":{"begin":428,"end":435},"obj":"GO:0008380"},{"id":"T5672","span":{"begin":461,"end":466},"obj":"SO_EXT:0000704"},{"id":"T5673","span":{"begin":498,"end":503},"obj":"SO_EXT:cDNA"},{"id":"T5674","span":{"begin":547,"end":565},"obj":"GO:0000380"},{"id":"T5675","span":{"begin":585,"end":603},"obj":"GO:0000380"},{"id":"T5676","span":{"begin":644,"end":650},"obj":"SO_EXT:0000204"},{"id":"T5677","span":{"begin":663,"end":667},"obj":"SO_EXT:0000147"},{"id":"T5678","span":{"begin":681,"end":697},"obj":"GO:0000380"},{"id":"T5679","span":{"begin":691,"end":703},"obj":"SO_EXT:splice_donor"},{"id":"T5680","span":{"begin":691,"end":697},"obj":"_FRAGMENT"},{"id":"T5681","span":{"begin":708,"end":717},"obj":"SO_EXT:splice_acceptor"}],"relations":[{"id":"R3507","pred":"_lexicallyChainedTo","subj":"T5681","obj":"T5680"}],"text":"Our cDNA collection reveals that at least two thirds of the olfactory receptors sampled show alternative splicing of their 5' untranslated exons. Using a custom script to process sim4 alignments of cDNA and genomic sequences, we find two to eight different splice forms for 85 (45%) of the 191 genes for which we have had some opportunity to observe alternate splicing (that is, a minimum of two cDNAs, at least one of which is spliced), and 55 (67%) of the 82 genes for which we have four or more cDNAs (and thus a higher chance of observing any alternate splicing) (Figure 5). These alternative splice events are almost all restricted to the 5' UTR and include exon skipping and alternate splice-donor and -acceptor use."}

    craft-ca-core-dev

    {"project":"craft-ca-core-dev","denotations":[{"id":"T5613","span":{"begin":60,"end":69},"obj":"GO:0007608"},{"id":"T5614","span":{"begin":93,"end":113},"obj":"GO:0000380"},{"id":"T5615","span":{"begin":123,"end":144},"obj":"SO:0000445"},{"id":"T5616","span":{"begin":128,"end":138},"obj":"GO:0006412"},{"id":"T5617","span":{"begin":207,"end":214},"obj":"SO:0001026"},{"id":"T5618","span":{"begin":257,"end":263},"obj":"GO:0008380"},{"id":"T5619","span":{"begin":294,"end":299},"obj":"SO:0000704"},{"id":"T5620","span":{"begin":350,"end":368},"obj":"GO:0000380"},{"id":"T5621","span":{"begin":428,"end":435},"obj":"GO:0008380"},{"id":"T5622","span":{"begin":461,"end":466},"obj":"SO:0000704"},{"id":"T5623","span":{"begin":547,"end":565},"obj":"GO:0000380"},{"id":"T5624","span":{"begin":585,"end":603},"obj":"GO:0000380"},{"id":"T5625","span":{"begin":644,"end":650},"obj":"SO:0000204"},{"id":"T5626","span":{"begin":663,"end":667},"obj":"SO:0000147"},{"id":"T5627","span":{"begin":681,"end":697},"obj":"GO:0000380"}],"text":"Our cDNA collection reveals that at least two thirds of the olfactory receptors sampled show alternative splicing of their 5' untranslated exons. Using a custom script to process sim4 alignments of cDNA and genomic sequences, we find two to eight different splice forms for 85 (45%) of the 191 genes for which we have had some opportunity to observe alternate splicing (that is, a minimum of two cDNAs, at least one of which is spliced), and 55 (67%) of the 82 genes for which we have four or more cDNAs (and thus a higher chance of observing any alternate splicing) (Figure 5). These alternative splice events are almost all restricted to the 5' UTR and include exon skipping and alternate splice-donor and -acceptor use."}