PMC:3245220 / 18292-19576
Annnotations
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T24908 | 44-49 | P09603 | denotes | M-CSF |
T24909 | 46-49 | P04141 | denotes | CSF |
T24910 | 89-93 | P25963 | denotes | IκBα |
T24911 | 149-152 | P21579 | denotes | p65 |
T24912 | 149-152 | Q04206 | denotes | p65 |
T24913 | 279-284 | P09603 | denotes | M-CSF |
T24914 | 281-284 | P04141 | denotes | CSF |
T24915 | 386-390 | P25963 | denotes | IκBα |
T24916 | 556-561 | P09603 | denotes | M-CSF |
T24917 | 558-561 | P04141 | denotes | CSF |
T24918 | 669-672 | P21579 | denotes | p65 |
T24919 | 669-672 | Q04206 | denotes | p65 |
T24920 | 747-750 | P21579 | denotes | p65 |
T24921 | 747-750 | Q04206 | denotes | p65 |
T24922 | 867-872 | P09603 | denotes | M-CSF |
T24923 | 869-872 | P04141 | denotes | CSF |
T24924 | 957-960 | Q04206 | denotes | p65 |
T24925 | 957-960 | P21579 | denotes | p65 |
T24926 | 1183-1188 | P04406 | denotes | GAPDH |
bionlp-st-ge-2016-reference
Id | Subject | Object | Predicate | Lexical cue | Negation | Speculation |
---|---|---|---|---|---|---|
T24927 | 80-88 | Regulation | denotes | regulate | true | |
T24928 | 94-105 | Protein_catabolism | denotes | degradation | ||
T24929 | 110-119 | Regulation | denotes | regulates | ||
T24930 | 124-139 | Phosphorylation | denotes | phosphorylation | ||
T24931 | 627-634 | Phosphorylation | denotes | phospho | true | |
T24932 | 645-652 | Phosphorylation | denotes | phospho | true | |
T24933 | 89-93 | Protein | denotes | IκBα | ||
T24934 | 635-641 | Entity | denotes | Ser276 | ||
T24935 | 653-659 | Entity | denotes | Ser536 | ||
T24936 | 149-152 | Protein | denotes | p65 | ||
T24937 | 669-672 | Protein | denotes | p65 | ||
T24938 | 747-750 | Protein | denotes | p65 | ||
T24939 | 156-162 | Entity | denotes | Ser276 | ||
T24940 | 44-49 | Protein | denotes | M-CSF | ||
T24941 | 279-284 | Protein | denotes | M-CSF | ||
T24942 | 556-561 | Protein | denotes | M-CSF | ||
T24943 | 867-872 | Protein | denotes | M-CSF | ||
T24944 | 844-851 | Negative_regulation | denotes | absence | ||
T24945 | 855-863 | Positive_regulation | denotes | presence | ||
R19084 | T24928 | T24927 | themeOf | degradation,regulate | ||
R19085 | T24930 | T24929 | themeOf | phosphorylation,regulates | ||
R19086 | T24933 | T24928 | themeOf | IκBα,degradation | ||
R19087 | T24934 | T24931 | themeOf | Ser276,phospho | ||
R19088 | T24934 | T24937 | partOf | Ser276,p65 | ||
R19089 | T24935 | T24932 | themeOf | Ser536,phospho | ||
R19090 | T24935 | T24937 | partOf | Ser536,p65 | ||
R19091 | T24939 | T24930 | themeOf | Ser276,phosphorylation | ||
R19092 | T24939 | T24936 | partOf | Ser276,p65 | ||
R19093 | T24940 | T24927 | causeOf | M-CSF,regulate | ||
R19094 | T24940 | T24929 | causeOf | M-CSF,regulates | ||
R19095 | T24943 | T24945 | themeOf | M-CSF,presence | ||
R19096 | T24943 | T24944 | themeOf | M-CSF,absence |
bionlp-st-ge-2016-reference-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T25079 | 44-49 | Protein | denotes | M-CSF |
T25080 | 58-61 | Protein | denotes | PKC |
T25081 | 89-109 | Protein | denotes | IκBα degradation but |
T25082 | 143-152 | Protein | denotes | NF-κB p65 |
T25083 | 50-57 | Positive_regulation | denotes | induced |
T25084 | 80-88 | Regulation | denotes | regulate |
T25085 | 110-119 | Regulation | denotes | regulates |
T25086 | 124-139 | Phosphorylation | denotes | phosphorylation |
T25087 | 279-284 | Protein | denotes | M-CSF |
T25088 | 381-399 | Protein | denotes | anti-IκBα antibody |
T25089 | 556-561 | Protein | denotes | M-CSF |
T25090 | 663-672 | Protein | denotes | NF-κB p65 |
T25091 | 741-750 | Protein | denotes | NF-κB p65 |
T25092 | 867-872 | Protein | denotes | M-CSF |
T25093 | 951-971 | Protein | denotes | NF-κB p65 antibodies |
T25094 | 1081-1094 | Protein | denotes | phospho-NF-κB |
T25095 | 1183-1188 | Protein | denotes | GAPDH |
T25096 | 1193-1200 | Protein | denotes | Lamin B |
R19165 | T25079 | T25083 | causeOf | M-CSF,induced |
R19166 | T25080 | T25083 | themeOf | PKC,induced |
R19167 | T25081 | T25084 | themeOf | IκBα degradation but,regulate |
R19168 | T25082 | T25086 | themeOf | NF-κB p65,phosphorylation |
R19169 | T25083 | T25085 | themeOf | induced,regulates |
events-check-again
Id | Subject | Object | Predicate | Lexical cue | Negation | Speculation |
---|---|---|---|---|---|---|
T25060 | 44-49 | Protein | denotes | M-CSF | ||
T25061 | 80-88 | Regulation | denotes | regulate | true | |
T25062 | 89-93 | Protein | denotes | IκBα | ||
T25063 | 94-105 | Protein_catabolism | denotes | degradation | ||
T25064 | 110-119 | Regulation | denotes | regulates | ||
T25065 | 124-139 | Phosphorylation | denotes | phosphorylation | ||
T25066 | 149-152 | Protein | denotes | p65 | ||
T25067 | 156-162 | Entity | denotes | Ser276 | ||
T25068 | 279-284 | Protein | denotes | M-CSF | ||
T25069 | 556-561 | Protein | denotes | M-CSF | ||
T25070 | 627-634 | Phosphorylation | denotes | phospho | true | |
T25071 | 635-641 | Entity | denotes | Ser276 | ||
T25072 | 645-652 | Phosphorylation | denotes | phospho | true | |
T25073 | 653-659 | Entity | denotes | Ser536 | ||
T25074 | 669-672 | Protein | denotes | p65 | ||
T25075 | 747-750 | Protein | denotes | p65 | ||
T25076 | 844-851 | Negative_regulation | denotes | absence | ||
T25077 | 855-863 | Positive_regulation | denotes | presence | ||
T25078 | 867-872 | Protein | denotes | M-CSF | ||
R19152 | T25060 | T25061 | causeOf | M-CSF,regulate | ||
R19153 | T25060 | T25064 | causeOf | M-CSF,regulates | ||
R19154 | T25062 | T25063 | themeOf | IκBα,degradation | ||
R19155 | T25063 | T25061 | themeOf | degradation,regulate | ||
R19156 | T25065 | T25064 | themeOf | phosphorylation,regulates | ||
R19157 | T25067 | T25065 | themeOf | Ser276,phosphorylation | ||
R19158 | T25067 | T25066 | partOf | Ser276,p65 | ||
R19159 | T25071 | T25070 | themeOf | Ser276,phospho | ||
R19160 | T25071 | T25074 | partOf | Ser276,p65 | ||
R19161 | T25073 | T25072 | themeOf | Ser536,phospho | ||
R19162 | T25073 | T25074 | partOf | Ser536,p65 | ||
R19163 | T25078 | T25077 | themeOf | M-CSF,presence | ||
R19164 | T25078 | T25076 | themeOf | M-CSF,absence |
GO-CC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T24957 | 328-332 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T24958 | 584-588 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T24959 | 762-766 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T24960 | 788-793 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T24961 | 1053-1058 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T24962 | 391-399 | http://purl.obolibrary.org/obo/GO_0019815 | denotes | antibody |
T24963 | 709-719 | http://purl.obolibrary.org/obo/GO_0019815 | denotes | antibodies |
T24964 | 961-971 | http://purl.obolibrary.org/obo/GO_0019815 | denotes | antibodies |
T24965 | 391-399 | http://purl.obolibrary.org/obo/GO_0042571 | denotes | antibody |
T24966 | 709-719 | http://purl.obolibrary.org/obo/GO_0042571 | denotes | antibodies |
T24967 | 961-971 | http://purl.obolibrary.org/obo/GO_0042571 | denotes | antibodies |
GO-MF
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T24953 | 58-70 | http://purl.obolibrary.org/obo/GO_0004697 | denotes | PKC activity |
T24954 | 391-399 | http://purl.obolibrary.org/obo/GO_0003823 | denotes | antibody |
T24955 | 709-719 | http://purl.obolibrary.org/obo/GO_0003823 | denotes | antibodies |
T24956 | 961-971 | http://purl.obolibrary.org/obo/GO_0003823 | denotes | antibodies |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T25097 | 94-105 | http://purl.obolibrary.org/obo/GO_0009056 | denotes | degradation |
T25098 | 124-139 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T24714 | 44-57 | JJ | denotes | M-CSF-induced |
T24715 | 58-61 | NN | denotes | PKC |
T24716 | 62-70 | NN | denotes | activity |
T24717 | 71-75 | VB | denotes | does |
T24718 | 76-79 | RB | denotes | not |
T24719 | 80-88 | VB | denotes | regulate |
T24720 | 89-93 | NN | denotes | IκBα |
T24721 | 94-105 | NN | denotes | degradation |
T24722 | 106-109 | CC | denotes | but |
T24723 | 110-119 | VB | denotes | regulates |
T24724 | 120-123 | DT | denotes | the |
T24725 | 124-139 | NN | denotes | phosphorylation |
T24726 | 140-142 | IN | denotes | of |
T24727 | 143-148 | NN | denotes | NF-κB |
T24728 | 149-152 | NN | denotes | p65 |
T24729 | 153-155 | IN | denotes | at |
T24730 | 156-162 | NN | denotes | Ser276 |
T24731 | 164-165 | -LRB- | denotes | ( |
T24732 | 165-166 | NN | denotes | A |
T24733 | 166-167 | -RRB- | denotes | ) |
T24734 | 168-172 | NN | denotes | MDMs |
T24735 | 173-177 | VB | denotes | were |
T24736 | 178-188 | VB | denotes | pretreated |
T24737 | 189-193 | IN | denotes | with |
T24738 | 194-207 | NN | denotes | cycloheximide |
T24739 | 208-209 | -LRB- | denotes | ( |
T24740 | 209-212 | NN | denotes | CHX |
T24741 | 212-213 | -RRB- | denotes | ) |
T24742 | 214-216 | IN | denotes | in |
T24743 | 217-220 | DT | denotes | the |
T24744 | 221-228 | NN | denotes | absence |
T24745 | 229-231 | CC | denotes | or |
T24746 | 232-240 | NN | denotes | presence |
T24747 | 241-243 | IN | denotes | of |
T24748 | 244-254 | NN | denotes | Ro-31-8220 |
T24749 | 255-258 | IN | denotes | for |
T24750 | 259-261 | CD | denotes | 30 |
T24751 | 262-269 | NN | denotes | minutes |
T24752 | 270-275 | RB | denotes | prior |
T24753 | 276-278 | TO | denotes | to |
T24754 | 279-284 | NN | denotes | M-CSF |
T24755 | 285-296 | NN | denotes | stimulation |
T24756 | 297-300 | IN | denotes | for |
T24757 | 301-304 | DT | denotes | the |
T24758 | 305-314 | JJ | denotes | indicated |
T24759 | 315-320 | NN | denotes | times |
T24760 | 322-327 | JJ | denotes | Whole |
T24761 | 328-332 | NN | denotes | cell |
T24762 | 333-340 | NN | denotes | lysates |
T24763 | 341-345 | VB | denotes | were |
T24764 | 346-355 | VB | denotes | subjected |
T24765 | 356-358 | TO | denotes | to |
T24766 | 359-366 | JJ | denotes | Western |
T24767 | 367-375 | NN | denotes | blotting |
T24768 | 376-380 | IN | denotes | with |
T24769 | 381-390 | JJ | denotes | anti-IκBα |
T24770 | 391-399 | NN | denotes | antibody |
T24771 | 401-405 | NN | denotes | Data |
T24772 | 406-409 | VB | denotes | are |
T24773 | 410-424 | JJ | denotes | representative |
T24774 | 425-427 | IN | denotes | of |
T24775 | 428-433 | CD | denotes | three |
T24776 | 434-445 | JJ | denotes | independent |
T24777 | 446-458 | NN | denotes | experiments. |
T24778 | 459-460 | -LRB- | denotes | ( |
T24779 | 460-461 | NN | denotes | B |
T24780 | 461-462 | -RRB- | denotes | ) |
T24781 | 463-467 | NN | denotes | MDMs |
T24782 | 468-472 | VB | denotes | were |
T24783 | 473-483 | VB | denotes | pretreated |
T24784 | 484-488 | IN | denotes | with |
T24785 | 489-495 | CC | denotes | either |
T24786 | 496-503 | NN | denotes | vehicle |
T24787 | 504-506 | CC | denotes | or |
T24788 | 507-517 | NN | denotes | Ro-31-8220 |
T24789 | 518-521 | IN | denotes | for |
T24790 | 522-524 | CD | denotes | 30 |
T24791 | 525-532 | NN | denotes | minutes |
T24792 | 533-539 | IN | denotes | before |
T24793 | 540-543 | DT | denotes | the |
T24794 | 544-552 | NN | denotes | addition |
T24795 | 553-555 | IN | denotes | of |
T24796 | 556-561 | NN | denotes | M-CSF |
T24797 | 562-565 | IN | denotes | for |
T24798 | 566-568 | CD | denotes | 10 |
T24799 | 569-576 | NN | denotes | minutes |
T24800 | 578-583 | JJ | denotes | Whole |
T24801 | 584-588 | NN | denotes | cell |
T24802 | 589-596 | NN | denotes | lysates |
T24803 | 597-601 | VB | denotes | were |
T24804 | 602-610 | VB | denotes | resolved |
T24805 | 611-613 | IN | denotes | by |
T24806 | 614-622 | NN | denotes | SDS-PAGE |
T24807 | 623-626 | CC | denotes | and |
T24808 | 627-641 | NN | denotes | phospho-Ser276 |
T24809 | 642-644 | CC | denotes | or |
T24810 | 645-659 | NN | denotes | phospho-Ser536 |
T24811 | 660-662 | IN | denotes | of |
T24812 | 663-668 | NN | denotes | NF-κB |
T24813 | 669-672 | NN | denotes | p65 |
T24814 | 673-676 | VB | denotes | was |
T24815 | 677-685 | VB | denotes | detected |
T24816 | 686-691 | VB | denotes | using |
T24817 | 692-708 | JJ | denotes | phospho-specific |
T24818 | 709-719 | NN | denotes | antibodies |
T24819 | 720-722 | TO | denotes | to |
T24820 | 723-729 | CC | denotes | either |
T24821 | 730-737 | NN | denotes | residue |
T24822 | 738-740 | IN | denotes | of |
T24823 | 741-746 | NN | denotes | NF-κB |
T24824 | 747-751 | NN | denotes | p65. |
T24825 | 752-753 | -LRB- | denotes | ( |
T24826 | 753-754 | NN | denotes | C |
T24827 | 754-755 | -RRB- | denotes | ) |
T24828 | 756-761 | JJ | denotes | Whole |
T24829 | 762-766 | NN | denotes | cell |
T24830 | 767-774 | NN | denotes | lysates |
T24831 | 775-777 | IN | denotes | of |
T24832 | 778-781 | NN | denotes | RAW |
T24833 | 782-787 | CD | denotes | 264.7 |
T24834 | 788-793 | NN | denotes | cells |
T24835 | 794-801 | VB | denotes | treated |
T24836 | 802-806 | IN | denotes | with |
T24837 | 807-814 | NN | denotes | vehicle |
T24838 | 815-822 | NN | denotes | control |
T24839 | 823-825 | CC | denotes | or |
T24840 | 826-836 | NN | denotes | Ro-31-8220 |
T24841 | 837-839 | IN | denotes | in |
T24842 | 840-843 | DT | denotes | the |
T24843 | 844-851 | NN | denotes | absence |
T24844 | 852-854 | CC | denotes | or |
T24845 | 855-863 | NN | denotes | presence |
T24846 | 864-866 | IN | denotes | of |
T24847 | 867-872 | NN | denotes | M-CSF |
T24848 | 873-877 | VB | denotes | were |
T24849 | 878-887 | VB | denotes | subjected |
T24850 | 888-890 | TO | denotes | to |
T24851 | 891-898 | JJ | denotes | Western |
T24852 | 899-903 | NN | denotes | blot |
T24853 | 904-912 | NN | denotes | analysis |
T24854 | 913-917 | IN | denotes | with |
T24855 | 918-932 | NN | denotes | phospho-Ser276 |
T24856 | 933-935 | CC | denotes | or |
T24857 | 936-950 | NN | denotes | phospho-Ser536 |
T24858 | 951-956 | NN | denotes | NF-κB |
T24859 | 957-960 | NN | denotes | p65 |
T24860 | 961-972 | NN | denotes | antibodies. |
T24861 | 973-974 | -LRB- | denotes | ( |
T24862 | 974-975 | NN | denotes | D |
T24863 | 975-976 | -RRB- | denotes | ) |
T24864 | 977-986 | JJ | denotes | Cytosolic |
T24865 | 987-990 | CC | denotes | and |
T24866 | 991-998 | JJ | denotes | nuclear |
T24867 | 999-1008 | NN | denotes | fractions |
T24868 | 1009-1011 | IN | denotes | of |
T24869 | 1012-1015 | NN | denotes | RAW |
T24870 | 1016-1021 | CD | denotes | 264.7 |
T24871 | 1022-1026 | VB | denotes | were |
T24872 | 1027-1035 | VB | denotes | obtained |
T24873 | 1036-1040 | IN | denotes | from |
T24874 | 1041-1044 | DT | denotes | the |
T24875 | 1045-1052 | VB | denotes | treated |
T24876 | 1053-1058 | NN | denotes | cells |
T24877 | 1059-1062 | CC | denotes | and |
T24878 | 1063-1076 | VB | denotes | immunoblotted |
T24879 | 1077-1080 | IN | denotes | for |
T24880 | 1081-1094 | NN | denotes | phospho-NF-κB |
T24881 | 1096-1099 | DT | denotes | The |
T24882 | 1100-1106 | NN | denotes | purity |
T24883 | 1107-1109 | IN | denotes | of |
T24884 | 1110-1113 | DT | denotes | the |
T24885 | 1114-1123 | JJ | denotes | cytosolic |
T24886 | 1124-1127 | CC | denotes | and |
T24887 | 1128-1135 | JJ | denotes | nuclear |
T24888 | 1136-1145 | NN | denotes | fractions |
T24889 | 1146-1149 | VB | denotes | was |
T24890 | 1150-1159 | VB | denotes | confirmed |
T24891 | 1160-1162 | IN | denotes | by |
T24892 | 1163-1177 | VB | denotes | immunoblotting |
T24893 | 1178-1182 | IN | denotes | with |
T24894 | 1183-1188 | NN | denotes | GAPDH |
T24895 | 1189-1192 | CC | denotes | and |
T24896 | 1193-1198 | NN | denotes | Lamin |
T24897 | 1199-1200 | NN | denotes | B |
T24898 | 1200-1201 | -COMMA- | denotes | , |
T24899 | 1202-1214 | RB | denotes | respectively |
T24900 | 1216-1221 | VB | denotes | Shown |
T24901 | 1222-1225 | VB | denotes | are |
T24902 | 1226-1240 | JJ | denotes | representative |
T24903 | 1241-1246 | NN | denotes | blots |
T24904 | 1247-1251 | IN | denotes | from |
T24905 | 1252-1257 | CD | denotes | three |
T24906 | 1258-1269 | JJ | denotes | independent |
T24907 | 1270-1281 | NN | denotes | experiments |
R18880 | T24716 | T24714 | arg1Of | activity,M-CSF-induced |
R18881 | T24716 | T24715 | arg1Of | activity,PKC |
R18882 | T24716 | T24717 | arg1Of | activity,does |
R18883 | T24716 | T24719 | arg1Of | activity,regulate |
R18884 | T24716 | T24723 | arg1Of | activity,regulates |
R18885 | T24719 | T24717 | arg2Of | regulate,does |
R18886 | T24719 | T24718 | arg1Of | regulate,not |
R18887 | T24719 | T24722 | arg1Of | regulate,but |
R18888 | T24721 | T24719 | arg2Of | degradation,regulate |
R18889 | T24721 | T24720 | arg1Of | degradation,IκBα |
R18890 | T24723 | T24722 | arg2Of | regulates,but |
R18891 | T24725 | T24723 | arg2Of | phosphorylation,regulates |
R18892 | T24725 | T24724 | arg1Of | phosphorylation,the |
R18893 | T24725 | T24726 | arg1Of | phosphorylation,of |
R18894 | T24728 | T24726 | arg2Of | p65,of |
R18895 | T24728 | T24727 | arg1Of | p65,NF-κB |
R18896 | T24728 | T24729 | arg1Of | p65,at |
R18897 | T24730 | T24729 | arg2Of | Ser276,at |
R18898 | T24732 | T24731 | arg2Of | A,( |
R18899 | T24733 | T24731 | arg3Of | ),( |
R18900 | T24734 | T24731 | arg1Of | MDMs,( |
R18901 | T24734 | T24735 | arg1Of | MDMs,were |
R18902 | T24734 | T24736 | arg2Of | MDMs,pretreated |
R18903 | T24736 | T24735 | arg2Of | pretreated,were |
R18904 | T24736 | T24737 | arg1Of | pretreated,with |
R18905 | T24736 | T24742 | arg1Of | pretreated,in |
R18906 | T24736 | T24749 | arg1Of | pretreated,for |
R18907 | T24738 | T24737 | arg2Of | cycloheximide,with |
R18908 | T24738 | T24739 | arg1Of | cycloheximide,( |
R18909 | T24740 | T24739 | arg2Of | CHX,( |
R18910 | T24741 | T24739 | arg3Of | ),( |
R18911 | T24744 | T24745 | arg1Of | absence,or |
R18912 | T24745 | T24742 | arg2Of | or,in |
R18913 | T24745 | T24743 | arg1Of | or,the |
R18914 | T24745 | T24747 | arg1Of | or,of |
R18915 | T24746 | T24745 | arg2Of | presence,or |
R18916 | T24748 | T24747 | arg2Of | Ro-31-8220,of |
R18917 | T24751 | T24749 | arg2Of | minutes,for |
R18918 | T24751 | T24750 | arg1Of | minutes,30 |
R18919 | T24751 | T24753 | arg1Of | minutes,to |
R18920 | T24753 | T24752 | arg1Of | to,prior |
R18921 | T24755 | T24753 | arg2Of | stimulation,to |
R18922 | T24755 | T24754 | arg1Of | stimulation,M-CSF |
R18923 | T24755 | T24756 | arg1Of | stimulation,for |
R18924 | T24759 | T24756 | arg2Of | times,for |
R18925 | T24759 | T24757 | arg1Of | times,the |
R18926 | T24759 | T24758 | arg1Of | times,indicated |
R18927 | T24762 | T24760 | arg1Of | lysates,Whole |
R18928 | T24762 | T24761 | arg1Of | lysates,cell |
R18929 | T24762 | T24763 | arg1Of | lysates,were |
R18930 | T24762 | T24764 | arg2Of | lysates,subjected |
R18931 | T24764 | T24763 | arg2Of | subjected,were |
R18932 | T24764 | T24765 | arg1Of | subjected,to |
R18933 | T24767 | T24765 | arg2Of | blotting,to |
R18934 | T24767 | T24766 | arg1Of | blotting,Western |
R18935 | T24767 | T24768 | arg1Of | blotting,with |
R18936 | T24770 | T24768 | arg2Of | antibody,with |
R18937 | T24770 | T24769 | arg1Of | antibody,anti-IκBα |
R18938 | T24771 | T24772 | arg1Of | Data,are |
R18939 | T24771 | T24773 | arg1Of | Data,representative |
R18940 | T24773 | T24772 | arg2Of | representative,are |
R18941 | T24773 | T24774 | arg1Of | representative,of |
R18942 | T24777 | T24774 | arg2Of | experiments.,of |
R18943 | T24777 | T24775 | arg1Of | experiments.,three |
R18944 | T24777 | T24776 | arg1Of | experiments.,independent |
R18945 | T24777 | T24778 | arg1Of | experiments.,( |
R18946 | T24779 | T24778 | arg2Of | B,( |
R18947 | T24780 | T24778 | arg3Of | ),( |
R18948 | T24781 | T24782 | arg1Of | MDMs,were |
R18949 | T24781 | T24783 | arg2Of | MDMs,pretreated |
R18950 | T24783 | T24773 | arg2Of | pretreated,representative |
R18951 | T24783 | T24782 | arg2Of | pretreated,were |
R18952 | T24783 | T24784 | arg1Of | pretreated,with |
R18953 | T24786 | T24787 | arg1Of | vehicle,or |
R18954 | T24787 | T24784 | arg2Of | or,with |
R18955 | T24787 | T24785 | arg1Of | or,either |
R18956 | T24787 | T24789 | arg1Of | or,for |
R18957 | T24788 | T24787 | arg2Of | Ro-31-8220,or |
R18958 | T24791 | T24789 | arg2Of | minutes,for |
R18959 | T24791 | T24790 | arg1Of | minutes,30 |
R18960 | T24791 | T24792 | arg1Of | minutes,before |
R18961 | T24794 | T24792 | arg2Of | addition,before |
R18962 | T24794 | T24793 | arg1Of | addition,the |
R18963 | T24794 | T24795 | arg1Of | addition,of |
R18964 | T24794 | T24797 | arg1Of | addition,for |
R18965 | T24796 | T24795 | arg2Of | M-CSF,of |
R18966 | T24799 | T24797 | arg2Of | minutes,for |
R18967 | T24799 | T24798 | arg1Of | minutes,10 |
R18968 | T24802 | T24800 | arg1Of | lysates,Whole |
R18969 | T24802 | T24801 | arg1Of | lysates,cell |
R18970 | T24802 | T24803 | arg1Of | lysates,were |
R18971 | T24802 | T24804 | arg2Of | lysates,resolved |
R18972 | T24802 | T24848 | arg1Of | lysates,were |
R18973 | T24802 | T24849 | arg2Of | lysates,subjected |
R18974 | T24804 | T24803 | arg2Of | resolved,were |
R18975 | T24804 | T24805 | arg1Of | resolved,by |
R18976 | T24804 | T24807 | arg1Of | resolved,and |
R18977 | T24806 | T24805 | arg2Of | SDS-PAGE,by |
R18978 | T24808 | T24809 | arg1Of | phospho-Ser276,or |
R18979 | T24809 | T24811 | arg1Of | or,of |
R18980 | T24809 | T24814 | arg1Of | or,was |
R18981 | T24809 | T24815 | arg2Of | or,detected |
R18982 | T24809 | T24816 | arg1Of | or,using |
R18983 | T24810 | T24809 | arg2Of | phospho-Ser536,or |
R18984 | T24813 | T24811 | arg2Of | p65,of |
R18985 | T24813 | T24812 | arg1Of | p65,NF-κB |
R18986 | T24815 | T24814 | arg2Of | detected,was |
R18987 | T24816 | T24815 | arg3Of | using,detected |
R18988 | T24818 | T24816 | arg2Of | antibodies,using |
R18989 | T24818 | T24817 | arg1Of | antibodies,phospho-specific |
R18990 | T24818 | T24819 | arg1Of | antibodies,to |
R18991 | T24821 | T24819 | arg2Of | residue,to |
R18992 | T24821 | T24820 | arg1Of | residue,either |
R18993 | T24821 | T24822 | arg1Of | residue,of |
R18994 | T24826 | T24825 | arg2Of | C,( |
R18995 | T24827 | T24825 | arg3Of | ),( |
R18996 | T24830 | T24822 | arg2Of | lysates,of |
R18997 | T24830 | T24823 | arg1Of | lysates,NF-κB |
R18998 | T24830 | T24824 | arg1Of | lysates,p65. |
R18999 | T24830 | T24825 | arg1Of | lysates,( |
R19000 | T24830 | T24828 | arg1Of | lysates,Whole |
R19001 | T24830 | T24829 | arg1Of | lysates,cell |
R19002 | T24830 | T24831 | arg1Of | lysates,of |
R19003 | T24834 | T24831 | arg2Of | cells,of |
R19004 | T24834 | T24832 | arg1Of | cells,RAW |
R19005 | T24834 | T24833 | arg1Of | cells,264.7 |
R19006 | T24834 | T24835 | arg2Of | cells,treated |
R19007 | T24835 | T24836 | arg1Of | treated,with |
R19008 | T24835 | T24841 | arg1Of | treated,in |
R19009 | T24838 | T24839 | arg1Of | control,or |
R19010 | T24839 | T24836 | arg2Of | or,with |
R19011 | T24839 | T24837 | arg1Of | or,vehicle |
R19012 | T24840 | T24839 | arg2Of | Ro-31-8220,or |
R19013 | T24843 | T24844 | arg1Of | absence,or |
R19014 | T24844 | T24841 | arg2Of | or,in |
R19015 | T24844 | T24842 | arg1Of | or,the |
R19016 | T24844 | T24846 | arg1Of | or,of |
R19017 | T24845 | T24844 | arg2Of | presence,or |
R19018 | T24847 | T24846 | arg2Of | M-CSF,of |
R19019 | T24849 | T24807 | arg2Of | subjected,and |
R19020 | T24849 | T24814 | modOf | subjected,was |
R19021 | T24849 | T24848 | arg2Of | subjected,were |
R19022 | T24849 | T24850 | arg1Of | subjected,to |
R19023 | T24853 | T24851 | arg1Of | analysis,Western |
R19024 | T24853 | T24852 | arg1Of | analysis,blot |
R19025 | T24853 | T24854 | arg1Of | analysis,with |
R19026 | T24853 | T24856 | arg1Of | analysis,or |
R19027 | T24855 | T24854 | arg2Of | phospho-Ser276,with |
R19028 | T24856 | T24850 | arg2Of | or,to |
R19029 | T24856 | T24871 | modOf | or,were |
R19030 | T24860 | T24856 | arg2Of | antibodies.,or |
R19031 | T24860 | T24857 | arg1Of | antibodies.,phospho-Ser536 |
R19032 | T24860 | T24858 | arg1Of | antibodies.,NF-κB |
R19033 | T24860 | T24859 | arg1Of | antibodies.,p65 |
R19034 | T24860 | T24861 | arg1Of | antibodies.,( |
R19035 | T24862 | T24861 | arg2Of | D,( |
R19036 | T24863 | T24861 | arg3Of | ),( |
R19037 | T24864 | T24865 | arg1Of | Cytosolic,and |
R19038 | T24866 | T24865 | arg2Of | nuclear,and |
R19039 | T24867 | T24864 | arg1Of | fractions,Cytosolic |
R19040 | T24867 | T24866 | arg1Of | fractions,nuclear |
R19041 | T24867 | T24868 | arg1Of | fractions,of |
R19042 | T24867 | T24871 | arg1Of | fractions,were |
R19043 | T24867 | T24872 | arg2Of | fractions,obtained |
R19044 | T24867 | T24878 | arg2Of | fractions,immunoblotted |
R19045 | T24869 | T24868 | arg2Of | RAW,of |
R19046 | T24869 | T24870 | arg1Of | RAW,264.7 |
R19047 | T24872 | T24873 | arg1Of | obtained,from |
R19048 | T24872 | T24877 | arg1Of | obtained,and |
R19049 | T24876 | T24873 | arg2Of | cells,from |
R19050 | T24876 | T24874 | arg1Of | cells,the |
R19051 | T24876 | T24875 | arg2Of | cells,treated |
R19052 | T24877 | T24871 | arg2Of | and,were |
R19053 | T24878 | T24877 | arg2Of | immunoblotted,and |
R19054 | T24878 | T24879 | arg1Of | immunoblotted,for |
R19055 | T24880 | T24879 | arg2Of | phospho-NF-κB,for |
R19056 | T24882 | T24881 | arg1Of | purity,The |
R19057 | T24882 | T24883 | arg1Of | purity,of |
R19058 | T24882 | T24889 | arg1Of | purity,was |
R19059 | T24882 | T24890 | arg2Of | purity,confirmed |
R19060 | T24885 | T24886 | arg1Of | cytosolic,and |
R19061 | T24887 | T24886 | arg2Of | nuclear,and |
R19062 | T24888 | T24883 | arg2Of | fractions,of |
R19063 | T24888 | T24884 | arg1Of | fractions,the |
R19064 | T24888 | T24885 | arg1Of | fractions,cytosolic |
R19065 | T24888 | T24887 | arg1Of | fractions,nuclear |
R19066 | T24890 | T24889 | arg2Of | confirmed,was |
R19067 | T24890 | T24891 | arg1Of | confirmed,by |
R19068 | T24890 | T24898 | arg1Of | confirmed,"," |
R19069 | T24890 | T24899 | arg1Of | confirmed,respectively |
R19070 | T24892 | T24891 | arg2Of | immunoblotting,by |
R19071 | T24892 | T24893 | arg1Of | immunoblotting,with |
R19072 | T24894 | T24895 | arg1Of | GAPDH,and |
R19073 | T24895 | T24893 | arg2Of | and,with |
R19074 | T24897 | T24895 | arg2Of | B,and |
R19075 | T24897 | T24896 | arg1Of | B,Lamin |
R19076 | T24901 | T24900 | modOf | are,Shown |
R19077 | T24903 | T24900 | arg2Of | blots,Shown |
R19078 | T24903 | T24901 | arg1Of | blots,are |
R19079 | T24903 | T24902 | arg1Of | blots,representative |
R19080 | T24903 | T24904 | arg1Of | blots,from |
R19081 | T24907 | T24904 | arg2Of | experiments,from |
R19082 | T24907 | T24905 | arg1Of | experiments,three |
R19083 | T24907 | T24906 | arg1Of | experiments,independent |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T24503 | 44-163 | Sentence | denotes | M-CSF-induced PKC activity does not regulate IκBα degradation but regulates the phosphorylation of NF-κB p65 at Ser276. |
T24504 | 164-321 | Sentence | denotes | (A) MDMs were pretreated with cycloheximide (CHX) in the absence or presence of Ro-31-8220 for 30 minutes prior to M-CSF stimulation for the indicated times. |
T24505 | 322-400 | Sentence | denotes | Whole cell lysates were subjected to Western blotting with anti-IκBα antibody. |
T24506 | 401-577 | Sentence | denotes | Data are representative of three independent experiments. (B) MDMs were pretreated with either vehicle or Ro-31-8220 for 30 minutes before the addition of M-CSF for 10 minutes. |
T24507 | 578-1095 | Sentence | denotes | Whole cell lysates were resolved by SDS-PAGE and phospho-Ser276 or phospho-Ser536 of NF-κB p65 was detected using phospho-specific antibodies to either residue of NF-κB p65. (C) Whole cell lysates of RAW 264.7 cells treated with vehicle control or Ro-31-8220 in the absence or presence of M-CSF were subjected to Western blot analysis with phospho-Ser276 or phospho-Ser536 NF-κB p65 antibodies. (D) Cytosolic and nuclear fractions of RAW 264.7 were obtained from the treated cells and immunoblotted for phospho-NF-κB. |
T24508 | 1096-1215 | Sentence | denotes | The purity of the cytosolic and nuclear fractions was confirmed by immunoblotting with GAPDH and Lamin B, respectively. |
T24509 | 1216-1282 | Sentence | denotes | Shown are representative blots from three independent experiments. |
T133 | 0-163 | Sentence | denotes | 10.1371/journal.pone.0028081.g005 Figure 5 M-CSF-induced PKC activity does not regulate IκBα degradation but regulates the phosphorylation of NF-κB p65 at Ser276. |
T134 | 164-321 | Sentence | denotes | (A) MDMs were pretreated with cycloheximide (CHX) in the absence or presence of Ro-31-8220 for 30 minutes prior to M-CSF stimulation for the indicated times. |
T135 | 322-400 | Sentence | denotes | Whole cell lysates were subjected to Western blotting with anti-IκBα antibody. |
T136 | 401-577 | Sentence | denotes | Data are representative of three independent experiments. (B) MDMs were pretreated with either vehicle or Ro-31-8220 for 30 minutes before the addition of M-CSF for 10 minutes. |
T137 | 578-1095 | Sentence | denotes | Whole cell lysates were resolved by SDS-PAGE and phospho-Ser276 or phospho-Ser536 of NF-κB p65 was detected using phospho-specific antibodies to either residue of NF-κB p65. (C) Whole cell lysates of RAW 264.7 cells treated with vehicle control or Ro-31-8220 in the absence or presence of M-CSF were subjected to Western blot analysis with phospho-Ser276 or phospho-Ser536 NF-κB p65 antibodies. (D) Cytosolic and nuclear fractions of RAW 264.7 were obtained from the treated cells and immunoblotted for phospho-NF-κB. |
T138 | 1096-1215 | Sentence | denotes | The purity of the cytosolic and nuclear fractions was confirmed by immunoblotting with GAPDH and Lamin B, respectively. |
T139 | 1216-1282 | Sentence | denotes | Shown are representative blots from three independent experiments. |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T24550 | 276-278 | TO | denotes | to |
T24510 | 44-57 | JJ | denotes | M-CSF-induced |
T24511 | 58-61 | NN | denotes | PKC |
T24512 | 62-70 | NN | denotes | activity |
T24513 | 71-75 | VBZ | denotes | does |
T24514 | 76-79 | RB | denotes | not |
T24515 | 80-88 | VB | denotes | regulate |
T24516 | 89-93 | NNP | denotes | IκBα |
T24517 | 94-105 | NN | denotes | degradation |
T24518 | 106-109 | CC | denotes | but |
T24519 | 110-119 | VBZ | denotes | regulates |
T24520 | 120-123 | DT | denotes | the |
T24521 | 124-139 | NN | denotes | phosphorylation |
T24522 | 140-142 | IN | denotes | of |
T24523 | 143-148 | NNP | denotes | NF-κB |
T24524 | 149-152 | NNS | denotes | p65 |
T24525 | 153-155 | IN | denotes | at |
T24526 | 156-162 | NNP | denotes | Ser276 |
T24527 | 162-163 | . | denotes | . |
T24528 | 164-165 | -LRB- | denotes | ( |
T24529 | 165-166 | NNP | denotes | A |
T24530 | 166-167 | -RRB- | denotes | ) |
T24531 | 168-172 | NNS | denotes | MDMs |
T24532 | 173-177 | VBD | denotes | were |
T24533 | 178-188 | VBN | denotes | pretreated |
T24534 | 189-193 | IN | denotes | with |
T24535 | 194-207 | NN | denotes | cycloheximide |
T24536 | 208-209 | -LRB- | denotes | ( |
T24537 | 209-212 | NNP | denotes | CHX |
T24538 | 212-213 | -RRB- | denotes | ) |
T24539 | 214-216 | IN | denotes | in |
T24540 | 217-220 | DT | denotes | the |
T24541 | 221-228 | NN | denotes | absence |
T24542 | 229-231 | CC | denotes | or |
T24543 | 232-240 | NN | denotes | presence |
T24544 | 241-243 | IN | denotes | of |
T24545 | 244-254 | NN | denotes | Ro-31-8220 |
T24546 | 255-258 | IN | denotes | for |
T24547 | 259-261 | CD | denotes | 30 |
T24548 | 262-269 | NNS | denotes | minutes |
T24549 | 270-275 | RB | denotes | prior |
T24551 | 279-284 | NNP | denotes | M-CSF |
T24552 | 285-296 | NN | denotes | stimulation |
T24553 | 297-300 | IN | denotes | for |
T24554 | 301-304 | DT | denotes | the |
T24555 | 305-314 | JJ | denotes | indicated |
T24556 | 315-320 | NNS | denotes | times |
T24557 | 320-321 | . | denotes | . |
T24558 | 322-327 | JJ | denotes | Whole |
T24559 | 328-332 | NN | denotes | cell |
T24560 | 333-340 | NNS | denotes | lysates |
T24561 | 341-345 | VBD | denotes | were |
T24562 | 346-355 | VBN | denotes | subjected |
T24563 | 356-358 | TO | denotes | to |
T24564 | 359-366 | JJ | denotes | Western |
T24565 | 367-375 | VBG | denotes | blotting |
T24566 | 376-380 | IN | denotes | with |
T24567 | 381-390 | JJ | denotes | anti-IκBα |
T24568 | 391-399 | NN | denotes | antibody |
T24569 | 399-400 | . | denotes | . |
T24570 | 401-405 | NNS | denotes | Data |
T24571 | 406-409 | VBP | denotes | are |
T24572 | 410-424 | NN | denotes | representative |
T24573 | 425-427 | IN | denotes | of |
T24574 | 428-433 | CD | denotes | three |
T24575 | 434-445 | JJ | denotes | independent |
T24576 | 446-457 | NNS | denotes | experiments |
T24577 | 457-458 | . | denotes | . |
T24578 | 459-460 | -LRB- | denotes | ( |
T24579 | 460-461 | NNP | denotes | B |
T24580 | 461-462 | -RRB- | denotes | ) |
T24581 | 463-467 | NNS | denotes | MDMs |
T24582 | 468-472 | VBD | denotes | were |
T24583 | 473-483 | VBN | denotes | pretreated |
T24584 | 484-488 | IN | denotes | with |
T24585 | 489-495 | DT | denotes | either |
T24586 | 496-503 | NN | denotes | vehicle |
T24587 | 504-506 | CC | denotes | or |
T24588 | 507-517 | NN | denotes | Ro-31-8220 |
T24589 | 518-521 | IN | denotes | for |
T24590 | 522-524 | CD | denotes | 30 |
T24591 | 525-532 | NNS | denotes | minutes |
T24592 | 533-539 | IN | denotes | before |
T24593 | 540-543 | DT | denotes | the |
T24594 | 544-552 | NN | denotes | addition |
T24595 | 553-555 | IN | denotes | of |
T24596 | 556-561 | NNP | denotes | M-CSF |
T24597 | 562-565 | IN | denotes | for |
T24598 | 566-568 | CD | denotes | 10 |
T24599 | 569-576 | NNS | denotes | minutes |
T24600 | 576-577 | . | denotes | . |
T24601 | 578-583 | JJ | denotes | Whole |
T24602 | 584-588 | NN | denotes | cell |
T24603 | 589-596 | NNS | denotes | lysates |
T24604 | 597-601 | VBD | denotes | were |
T24605 | 602-610 | VBN | denotes | resolved |
T24606 | 611-613 | IN | denotes | by |
T24607 | 614-622 | NNP | denotes | SDS-PAGE |
T24608 | 623-626 | CC | denotes | and |
T24609 | 627-641 | NNP | denotes | phospho-Ser276 |
T24610 | 642-644 | CC | denotes | or |
T24611 | 645-659 | NNP | denotes | phospho-Ser536 |
T24612 | 660-662 | IN | denotes | of |
T24613 | 663-668 | NNP | denotes | NF-κB |
T24614 | 669-672 | CD | denotes | p65 |
T24615 | 673-676 | VBD | denotes | was |
T24616 | 677-685 | VBN | denotes | detected |
T24617 | 686-691 | VBG | denotes | using |
T24618 | 692-708 | JJ | denotes | phospho-specific |
T24619 | 709-719 | NNS | denotes | antibodies |
T24620 | 720-722 | TO | denotes | to |
T24621 | 723-729 | DT | denotes | either |
T24622 | 730-737 | NN | denotes | residue |
T24623 | 738-740 | IN | denotes | of |
T24624 | 741-746 | NNP | denotes | NF-κB |
T24625 | 747-750 | NNS | denotes | p65 |
T24626 | 750-751 | . | denotes | . |
T24627 | 752-753 | -LRB- | denotes | ( |
T24628 | 753-754 | $ | denotes | C |
T24629 | 754-755 | -RRB- | denotes | ) |
T24630 | 756-761 | JJ | denotes | Whole |
T24631 | 762-766 | NN | denotes | cell |
T24632 | 767-774 | NNS | denotes | lysates |
T24633 | 775-777 | IN | denotes | of |
T24634 | 778-781 | NNP | denotes | RAW |
T24635 | 782-787 | CD | denotes | 264.7 |
T24636 | 788-793 | NNS | denotes | cells |
T24637 | 794-801 | VBN | denotes | treated |
T24638 | 802-806 | IN | denotes | with |
T24639 | 807-814 | NN | denotes | vehicle |
T24640 | 815-822 | NN | denotes | control |
T24641 | 823-825 | CC | denotes | or |
T24642 | 826-836 | NN | denotes | Ro-31-8220 |
T24643 | 837-839 | IN | denotes | in |
T24644 | 840-843 | DT | denotes | the |
T24645 | 844-851 | NN | denotes | absence |
T24646 | 852-854 | CC | denotes | or |
T24647 | 855-863 | NN | denotes | presence |
T24648 | 864-866 | IN | denotes | of |
T24649 | 867-872 | NNP | denotes | M-CSF |
T24650 | 873-877 | VBD | denotes | were |
T24651 | 878-887 | VBN | denotes | subjected |
T24652 | 888-890 | TO | denotes | to |
T24653 | 891-898 | JJ | denotes | Western |
T24654 | 899-903 | NN | denotes | blot |
T24655 | 904-912 | NN | denotes | analysis |
T24656 | 913-917 | IN | denotes | with |
T24657 | 918-932 | NN | denotes | phospho-Ser276 |
T24658 | 933-935 | CC | denotes | or |
T24659 | 936-950 | NN | denotes | phospho-Ser536 |
T24660 | 951-956 | NNP | denotes | NF-κB |
T24661 | 957-960 | CD | denotes | p65 |
T24662 | 961-971 | NNS | denotes | antibodies |
T24663 | 971-972 | . | denotes | . |
T24664 | 973-974 | -LRB- | denotes | ( |
T24665 | 974-975 | NNP | denotes | D |
T24666 | 975-976 | -RRB- | denotes | ) |
T24667 | 977-986 | NNP | denotes | Cytosolic |
T24668 | 987-990 | CC | denotes | and |
T24669 | 991-998 | JJ | denotes | nuclear |
T24670 | 999-1008 | NNS | denotes | fractions |
T24671 | 1009-1011 | IN | denotes | of |
T24672 | 1012-1015 | NNP | denotes | RAW |
T24673 | 1016-1021 | CD | denotes | 264.7 |
T24674 | 1022-1026 | VBD | denotes | were |
T24675 | 1027-1035 | VBN | denotes | obtained |
T24676 | 1036-1040 | IN | denotes | from |
T24677 | 1041-1044 | DT | denotes | the |
T24678 | 1045-1052 | VBN | denotes | treated |
T24679 | 1053-1058 | NNS | denotes | cells |
T24680 | 1059-1062 | CC | denotes | and |
T24681 | 1063-1076 | VBN | denotes | immunoblotted |
T24682 | 1077-1080 | IN | denotes | for |
T24683 | 1081-1094 | NN | denotes | phospho-NF-κB |
T24684 | 1094-1095 | . | denotes | . |
T24685 | 1096-1099 | DT | denotes | The |
T24686 | 1100-1106 | NN | denotes | purity |
T24687 | 1107-1109 | IN | denotes | of |
T24688 | 1110-1113 | DT | denotes | the |
T24689 | 1114-1123 | JJ | denotes | cytosolic |
T24690 | 1124-1127 | CC | denotes | and |
T24691 | 1128-1135 | JJ | denotes | nuclear |
T24692 | 1136-1145 | NNS | denotes | fractions |
T24693 | 1146-1149 | VBD | denotes | was |
T24694 | 1150-1159 | VBN | denotes | confirmed |
T24695 | 1160-1162 | IN | denotes | by |
T24696 | 1163-1177 | VBG | denotes | immunoblotting |
T24697 | 1178-1182 | IN | denotes | with |
T24698 | 1183-1188 | NNP | denotes | GAPDH |
T24699 | 1189-1192 | CC | denotes | and |
T24700 | 1193-1198 | NNP | denotes | Lamin |
T24701 | 1199-1200 | NNP | denotes | B |
T24702 | 1200-1201 | , | denotes | , |
T24703 | 1202-1214 | RB | denotes | respectively |
T24704 | 1214-1215 | . | denotes | . |
T24705 | 1216-1221 | VBN | denotes | Shown |
T24706 | 1222-1225 | VBP | denotes | are |
T24707 | 1226-1240 | JJ | denotes | representative |
T24708 | 1241-1246 | NNS | denotes | blots |
T24709 | 1247-1251 | IN | denotes | from |
T24710 | 1252-1257 | CD | denotes | three |
T24711 | 1258-1269 | JJ | denotes | independent |
T24712 | 1270-1281 | NNS | denotes | experiments |
T24713 | 1281-1282 | . | denotes | . |
R18676 | T24510 | T24512 | amod | M-CSF-induced,activity |
R18677 | T24511 | T24512 | compound | PKC,activity |
R18678 | T24512 | T24515 | nsubj | activity,regulate |
R18679 | T24513 | T24515 | aux | does,regulate |
R18680 | T24514 | T24515 | neg | not,regulate |
R18681 | T24515 | T24515 | ROOT | regulate,regulate |
R18682 | T24516 | T24517 | compound | IκBα,degradation |
R18683 | T24517 | T24515 | dobj | degradation,regulate |
R18684 | T24518 | T24515 | cc | but,regulate |
R18685 | T24519 | T24515 | conj | regulates,regulate |
R18686 | T24520 | T24521 | det | the,phosphorylation |
R18687 | T24521 | T24519 | dobj | phosphorylation,regulates |
R18688 | T24522 | T24521 | prep | of,phosphorylation |
R18689 | T24523 | T24524 | compound | NF-κB,p65 |
R18690 | T24524 | T24522 | pobj | p65,of |
R18691 | T24525 | T24519 | prep | at,regulates |
R18692 | T24526 | T24525 | pobj | Ser276,at |
R18693 | T24527 | T24515 | punct | .,regulate |
R18694 | T24528 | T24529 | punct | (,A |
R18695 | T24529 | T24529 | ROOT | A,A |
R18696 | T24530 | T24529 | punct | ),A |
R18697 | T24531 | T24533 | nsubjpass | MDMs,pretreated |
R18698 | T24532 | T24533 | auxpass | were,pretreated |
R18699 | T24533 | T24533 | ROOT | pretreated,pretreated |
R18700 | T24534 | T24533 | prep | with,pretreated |
R18701 | T24535 | T24534 | pobj | cycloheximide,with |
R18702 | T24536 | T24535 | punct | (,cycloheximide |
R18703 | T24537 | T24535 | appos | CHX,cycloheximide |
R18704 | T24538 | T24535 | punct | ),cycloheximide |
R18713 | T24547 | T24548 | nummod | 30,minutes |
R18714 | T24548 | T24546 | pobj | minutes,for |
R18715 | T24549 | T24533 | advmod | prior,pretreated |
R18716 | T24550 | T24549 | prep | to,prior |
R18717 | T24551 | T24552 | compound | M-CSF,stimulation |
R18718 | T24552 | T24550 | pobj | stimulation,to |
R18719 | T24553 | T24549 | prep | for,prior |
R18720 | T24554 | T24556 | det | the,times |
R18721 | T24555 | T24556 | amod | indicated,times |
R18722 | T24556 | T24553 | pobj | times,for |
R18723 | T24557 | T24533 | punct | .,pretreated |
R18724 | T24558 | T24560 | amod | Whole,lysates |
R18725 | T24559 | T24560 | compound | cell,lysates |
R18726 | T24560 | T24562 | nsubjpass | lysates,subjected |
R18727 | T24561 | T24562 | auxpass | were,subjected |
R18728 | T24562 | T24562 | ROOT | subjected,subjected |
R18729 | T24563 | T24562 | prep | to,subjected |
R18730 | T24564 | T24565 | amod | Western,blotting |
R18731 | T24565 | T24563 | pobj | blotting,to |
R18732 | T24566 | T24562 | prep | with,subjected |
R18733 | T24567 | T24568 | amod | anti-IκBα,antibody |
R18734 | T24568 | T24566 | pobj | antibody,with |
R18735 | T24569 | T24562 | punct | .,subjected |
R18736 | T24570 | T24571 | nsubj | Data,are |
R18737 | T24571 | T24571 | ROOT | are,are |
R18738 | T24572 | T24571 | attr | representative,are |
R18739 | T24573 | T24572 | prep | of,representative |
R18740 | T24574 | T24576 | nummod | three,experiments |
R18741 | T24575 | T24576 | amod | independent,experiments |
R18742 | T24576 | T24573 | pobj | experiments,of |
R18743 | T24577 | T24571 | punct | .,are |
R18744 | T24578 | T24579 | punct | (,B |
R18745 | T24579 | T24579 | ROOT | B,B |
R18746 | T24580 | T24579 | punct | ),B |
R18747 | T24581 | T24583 | nsubjpass | MDMs,pretreated |
R18748 | T24582 | T24583 | auxpass | were,pretreated |
R18749 | T24583 | T24583 | ROOT | pretreated,pretreated |
R18750 | T24584 | T24583 | prep | with,pretreated |
R18751 | T24585 | T24586 | det | either,vehicle |
R18752 | T24586 | T24584 | pobj | vehicle,with |
R18753 | T24587 | T24586 | cc | or,vehicle |
R18754 | T24588 | T24586 | conj | Ro-31-8220,vehicle |
R18755 | T24589 | T24583 | prep | for,pretreated |
R18756 | T24590 | T24591 | nummod | 30,minutes |
R18757 | T24591 | T24589 | pobj | minutes,for |
R18758 | T24592 | T24591 | prep | before,minutes |
R18759 | T24593 | T24594 | det | the,addition |
R18760 | T24594 | T24592 | pobj | addition,before |
R18761 | T24595 | T24594 | prep | of,addition |
R18762 | T24596 | T24595 | pobj | M-CSF,of |
R18763 | T24597 | T24583 | prep | for,pretreated |
R18764 | T24598 | T24599 | nummod | 10,minutes |
R18765 | T24599 | T24597 | pobj | minutes,for |
R18766 | T24600 | T24583 | punct | .,pretreated |
R18767 | T24601 | T24602 | amod | Whole,cell |
R18768 | T24602 | T24603 | compound | cell,lysates |
R18769 | T24603 | T24605 | nsubjpass | lysates,resolved |
R18770 | T24604 | T24605 | auxpass | were,resolved |
R18771 | T24605 | T24605 | ROOT | resolved,resolved |
R18772 | T24606 | T24605 | agent | by,resolved |
R18773 | T24607 | T24606 | pobj | SDS-PAGE,by |
R18774 | T24608 | T24607 | cc | and,SDS-PAGE |
R18775 | T24609 | T24607 | conj | phospho-Ser276,SDS-PAGE |
R18776 | T24610 | T24609 | cc | or,phospho-Ser276 |
R18777 | T24611 | T24609 | conj | phospho-Ser536,phospho-Ser276 |
R18778 | T24612 | T24611 | prep | of,phospho-Ser536 |
R18779 | T24613 | T24612 | pobj | NF-κB,of |
R18780 | T24614 | T24613 | nummod | p65,NF-κB |
R18781 | T24615 | T24616 | auxpass | was,detected |
R18782 | T24616 | T24605 | conj | detected,resolved |
R18783 | T24617 | T24616 | advcl | using,detected |
R18784 | T24618 | T24619 | amod | phospho-specific,antibodies |
R18785 | T24619 | T24617 | dobj | antibodies,using |
R18786 | T24620 | T24617 | prep | to,using |
R18787 | T24621 | T24622 | det | either,residue |
R18788 | T24622 | T24620 | pobj | residue,to |
R18789 | T24623 | T24622 | prep | of,residue |
R18790 | T24624 | T24625 | compound | NF-κB,p65 |
R18791 | T24625 | T24623 | pobj | p65,of |
R18792 | T24626 | T24605 | punct | .,resolved |
R18793 | T24627 | T24628 | punct | (,C |
R18794 | T24628 | T24632 | nmod | C,lysates |
R18795 | T24629 | T24628 | punct | ),C |
R18796 | T24630 | T24631 | amod | Whole,cell |
R18797 | T24631 | T24632 | compound | cell,lysates |
R18798 | T24632 | T24651 | nsubjpass | lysates,subjected |
R18799 | T24633 | T24632 | prep | of,lysates |
R18800 | T24634 | T24633 | pobj | RAW,of |
R18801 | T24635 | T24634 | nummod | 264.7,RAW |
R18802 | T24636 | T24632 | conj | cells,lysates |
R18803 | T24637 | T24632 | acl | treated,lysates |
R18804 | T24638 | T24637 | prep | with,treated |
R18805 | T24639 | T24640 | compound | vehicle,control |
R18806 | T24640 | T24638 | pobj | control,with |
R18807 | T24641 | T24640 | cc | or,control |
R18808 | T24642 | T24640 | conj | Ro-31-8220,control |
R18809 | T24643 | T24637 | prep | in,treated |
R18810 | T24644 | T24645 | det | the,absence |
R18811 | T24645 | T24643 | pobj | absence,in |
R18812 | T24646 | T24645 | cc | or,absence |
R18813 | T24647 | T24645 | conj | presence,absence |
R18814 | T24648 | T24645 | prep | of,absence |
R18815 | T24649 | T24648 | pobj | M-CSF,of |
R18816 | T24650 | T24651 | auxpass | were,subjected |
R18817 | T24651 | T24651 | ROOT | subjected,subjected |
R18818 | T24652 | T24651 | prep | to,subjected |
R18819 | T24653 | T24655 | amod | Western,analysis |
R18820 | T24654 | T24655 | compound | blot,analysis |
R18821 | T24655 | T24652 | pobj | analysis,to |
R18822 | T24656 | T24655 | prep | with,analysis |
R18823 | T24657 | T24656 | pobj | phospho-Ser276,with |
R18824 | T24658 | T24657 | cc | or,phospho-Ser276 |
R18825 | T24659 | T24660 | compound | phospho-Ser536,NF-κB |
R18826 | T24660 | T24657 | conj | NF-κB,phospho-Ser276 |
R18827 | T24661 | T24662 | nummod | p65,antibodies |
R18828 | T24662 | T24656 | pobj | antibodies,with |
R18829 | T24663 | T24651 | punct | .,subjected |
R18830 | T24664 | T24667 | punct | (,Cytosolic |
R18831 | T24665 | T24667 | nmod | D,Cytosolic |
R18832 | T24666 | T24667 | punct | ),Cytosolic |
R18833 | T24667 | T24675 | nsubjpass | Cytosolic,obtained |
R18834 | T24668 | T24667 | cc | and,Cytosolic |
R18835 | T24669 | T24670 | amod | nuclear,fractions |
R18836 | T24670 | T24667 | conj | fractions,Cytosolic |
R18837 | T24671 | T24670 | prep | of,fractions |
R18838 | T24672 | T24675 | nsubjpass | RAW,obtained |
R18839 | T24673 | T24672 | nummod | 264.7,RAW |
R18840 | T24674 | T24675 | auxpass | were,obtained |
R18841 | T24675 | T24675 | ROOT | obtained,obtained |
R18842 | T24676 | T24675 | prep | from,obtained |
R18843 | T24677 | T24679 | det | the,cells |
R18844 | T24678 | T24679 | amod | treated,cells |
R18845 | T24679 | T24676 | pobj | cells,from |
R18846 | T24680 | T24675 | cc | and,obtained |
R18847 | T24681 | T24675 | conj | immunoblotted,obtained |
R18848 | T24682 | T24681 | prep | for,immunoblotted |
R18849 | T24683 | T24682 | pobj | phospho-NF-κB,for |
R18850 | T24684 | T24675 | punct | .,obtained |
R18851 | T24685 | T24686 | det | The,purity |
R18852 | T24686 | T24694 | nsubjpass | purity,confirmed |
R18853 | T24687 | T24686 | prep | of,purity |
R18854 | T24688 | T24692 | det | the,fractions |
R18855 | T24689 | T24692 | amod | cytosolic,fractions |
R18856 | T24690 | T24689 | cc | and,cytosolic |
R18857 | T24691 | T24689 | conj | nuclear,cytosolic |
R18858 | T24692 | T24687 | pobj | fractions,of |
R18859 | T24693 | T24694 | auxpass | was,confirmed |
R18860 | T24694 | T24694 | ROOT | confirmed,confirmed |
R18861 | T24695 | T24694 | agent | by,confirmed |
R18862 | T24696 | T24695 | pcomp | immunoblotting,by |
R18863 | T24697 | T24696 | prep | with,immunoblotting |
R18864 | T24698 | T24697 | pobj | GAPDH,with |
R18865 | T24699 | T24698 | cc | and,GAPDH |
R18866 | T24700 | T24701 | compound | Lamin,B |
R18867 | T24701 | T24698 | conj | B,GAPDH |
R18868 | T24702 | T24696 | punct | ",",immunoblotting |
R18869 | T24703 | T24696 | advmod | respectively,immunoblotting |
R18870 | T24704 | T24694 | punct | .,confirmed |
R18872 | T24706 | T24705 | auxpass | are,Shown |
R18873 | T24707 | T24708 | compound | representative,blots |
R18874 | T24708 | T24705 | nsubjpass | blots,Shown |
R18875 | T24709 | T24708 | prep | from,blots |
R18876 | T24710 | T24712 | nummod | three,experiments |
R18877 | T24711 | T24712 | amod | independent,experiments |
R18878 | T24712 | T24709 | pobj | experiments,from |
R18879 | T24713 | T24705 | punct | .,Shown |
R18705 | T24539 | T24533 | prep | in,pretreated |
R18706 | T24540 | T24541 | det | the,absence |
R18707 | T24541 | T24539 | pobj | absence,in |
R18708 | T24542 | T24541 | cc | or,absence |
R18709 | T24543 | T24541 | conj | presence,absence |
R18710 | T24544 | T24541 | prep | of,absence |
R18711 | T24545 | T24544 | pobj | Ro-31-8220,of |
R18712 | T24546 | T24533 | prep | for,pretreated |
R18871 | T24705 | T24705 | ROOT | Shown,Shown |
test2
Id | Subject | Object | Predicate | Lexical cue | Negation | Speculation |
---|---|---|---|---|---|---|
T24487 | 44-49 | Protein | denotes | M-CSF | true | |
T24488 | 80-88 | Regulation | denotes | regulate | ||
T24489 | 89-93 | Protein | denotes | IκBα | ||
T24490 | 94-105 | Protein_catabolism | denotes | degradation | ||
T24491 | 110-119 | Regulation | denotes | regulates | true | |
T24492 | 124-139 | Phosphorylation | denotes | phosphorylation | true | |
T24493 | 149-152 | Protein | denotes | p65 | ||
T24494 | 156-162 | Entity | denotes | Ser276 | ||
T24495 | 279-284 | Protein | denotes | M-CSF | ||
T24496 | 556-561 | Protein | denotes | M-CSF | ||
T24497 | 645-652 | Phosphorylation | denotes | phospho | ||
T24498 | 669-672 | Protein | denotes | p65 | ||
T24499 | 747-750 | Protein | denotes | p65 | ||
T24500 | 867-872 | Protein | denotes | M-CSF | ||
T24501 | 918-925 | Phosphorylation | denotes | phospho | ||
T24502 | 936-943 | Phosphorylation | denotes | phospho | ||
R18669 | T24487 | T24488 | causeOf | M-CSF,regulate | ||
R18670 | T24487 | T24491 | causeOf | M-CSF,regulates | ||
R18671 | T24489 | T24490 | themeOf | IκBα,degradation | ||
R18672 | T24490 | T24488 | themeOf | degradation,regulate | ||
R18673 | T24492 | T24491 | themeOf | phosphorylation,regulates | ||
R18674 | T24494 | T24493 | partOf | Ser276,p65 | ||
R18675 | T24494 | T24492 | themeOf | Ser276,phosphorylation |