PMC:3218875 / 83-672
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/3218875","sourcedb":"PMC","sourceid":"3218875","source_url":"http://www.ncbi.nlm.nih.gov/pmc/3218875","text":"The transcription factor NF-κB plays crucial roles in the regulation of inflammation and mmune responses, and inappropriate NF-κB activity has been linked with many autoimmune and inflammatory diseases, including rheumatoid arthritis. Cells employ a multilayered control system to keep NF-κB signalling in check, including a repertoire of negative feedback regulators ensuring termination of NF-κB responses. Here we will review various negative regulatory mechanisms that have evolved to control NF-κB signalling and which have been implicated in the pathogenesis of rheumatoid arthritis.","tracks":[{"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T210","span":{"begin":588,"end":589},"obj":"."},{"id":"T209","span":{"begin":579,"end":588},"obj":"NNS"},{"id":"T208","span":{"begin":568,"end":578},"obj":"JJ"},{"id":"T207","span":{"begin":565,"end":567},"obj":"IN"},{"id":"T206","span":{"begin":552,"end":564},"obj":"NN"},{"id":"T205","span":{"begin":548,"end":551},"obj":"DT"},{"id":"T204","span":{"begin":545,"end":547},"obj":"IN"},{"id":"T203","span":{"begin":534,"end":544},"obj":"VBN"},{"id":"T202","span":{"begin":529,"end":533},"obj":"VBN"},{"id":"T201","span":{"begin":524,"end":528},"obj":"VBP"},{"id":"T200","span":{"begin":518,"end":523},"obj":"WDT"},{"id":"T199","span":{"begin":514,"end":517},"obj":"CC"},{"id":"T198","span":{"begin":503,"end":513},"obj":"NN"},{"id":"T197","span":{"begin":497,"end":502},"obj":"JJ"},{"id":"T196","span":{"begin":489,"end":496},"obj":"VB"},{"id":"T195","span":{"begin":486,"end":488},"obj":"TO"},{"id":"T194","span":{"begin":478,"end":485},"obj":"VBN"},{"id":"T193","span":{"begin":473,"end":477},"obj":"VBP"},{"id":"T192","span":{"begin":468,"end":472},"obj":"WDT"},{"id":"T191","span":{"begin":457,"end":467},"obj":"NNS"},{"id":"T190","span":{"begin":446,"end":456},"obj":"JJ"},{"id":"T189","span":{"begin":437,"end":445},"obj":"JJ"},{"id":"T188","span":{"begin":429,"end":436},"obj":"JJ"},{"id":"T187","span":{"begin":422,"end":428},"obj":"VB"},{"id":"T186","span":{"begin":417,"end":421},"obj":"MD"},{"id":"T185","span":{"begin":414,"end":416},"obj":"PRP"},{"id":"T184","span":{"begin":409,"end":413},"obj":"RB"},{"id":"T183","span":{"begin":407,"end":408},"obj":"."},{"id":"T182","span":{"begin":398,"end":407},"obj":"NNS"},{"id":"T181","span":{"begin":392,"end":397},"obj":"JJ"},{"id":"T180","span":{"begin":389,"end":391},"obj":"IN"},{"id":"T179","span":{"begin":377,"end":388},"obj":"NN"},{"id":"T178","span":{"begin":368,"end":376},"obj":"VBG"},{"id":"T177","span":{"begin":357,"end":367},"obj":"NNS"},{"id":"T176","span":{"begin":348,"end":356},"obj":"NN"},{"id":"T175","span":{"begin":339,"end":347},"obj":"JJ"},{"id":"T174","span":{"begin":336,"end":338},"obj":"IN"},{"id":"T173","span":{"begin":325,"end":335},"obj":"NN"},{"id":"T172","span":{"begin":323,"end":324},"obj":"DT"},{"id":"T171","span":{"begin":313,"end":322},"obj":"VBG"},{"id":"T170","span":{"begin":311,"end":312},"obj":","},{"id":"T169","span":{"begin":306,"end":311},"obj":"NN"},{"id":"T168","span":{"begin":303,"end":305},"obj":"IN"},{"id":"T167","span":{"begin":292,"end":302},"obj":"NN"},{"id":"T166","span":{"begin":286,"end":291},"obj":"JJ"},{"id":"T165","span":{"begin":281,"end":285},"obj":"VB"},{"id":"T164","span":{"begin":278,"end":280},"obj":"TO"},{"id":"T163","span":{"begin":271,"end":277},"obj":"NN"},{"id":"T162","span":{"begin":263,"end":270},"obj":"NN"},{"id":"T161","span":{"begin":250,"end":262},"obj":"JJ"},{"id":"T160","span":{"begin":248,"end":249},"obj":"DT"},{"id":"T159","span":{"begin":241,"end":247},"obj":"VBP"},{"id":"T158","span":{"begin":235,"end":240},"obj":"NNS"},{"id":"T157","span":{"begin":233,"end":234},"obj":"."},{"id":"T156","span":{"begin":224,"end":233},"obj":"NNS"},{"id":"T155","span":{"begin":213,"end":223},"obj":"JJ"},{"id":"T154","span":{"begin":203,"end":212},"obj":"VBG"},{"id":"T153","span":{"begin":201,"end":202},"obj":","},{"id":"T152","span":{"begin":193,"end":201},"obj":"NNS"},{"id":"T151","span":{"begin":180,"end":192},"obj":"JJ"},{"id":"T150","span":{"begin":176,"end":179},"obj":"CC"},{"id":"T149","span":{"begin":165,"end":175},"obj":"JJ"},{"id":"T148","span":{"begin":160,"end":164},"obj":"JJ"},{"id":"T147","span":{"begin":155,"end":159},"obj":"IN"},{"id":"T146","span":{"begin":148,"end":154},"obj":"VBN"},{"id":"T145","span":{"begin":143,"end":147},"obj":"VBN"},{"id":"T144","span":{"begin":139,"end":142},"obj":"VBZ"},{"id":"T143","span":{"begin":130,"end":138},"obj":"NN"},{"id":"T142","span":{"begin":124,"end":129},"obj":"NN"},{"id":"T141","span":{"begin":110,"end":123},"obj":"JJ"},{"id":"T140","span":{"begin":106,"end":109},"obj":"CC"},{"id":"T139","span":{"begin":104,"end":105},"obj":","},{"id":"T138","span":{"begin":95,"end":104},"obj":"NNS"},{"id":"T137","span":{"begin":89,"end":94},"obj":"NN"},{"id":"T136","span":{"begin":85,"end":88},"obj":"CC"},{"id":"T135","span":{"begin":72,"end":84},"obj":"NN"},{"id":"T134","span":{"begin":69,"end":71},"obj":"IN"},{"id":"T133","span":{"begin":58,"end":68},"obj":"NN"},{"id":"T132","span":{"begin":54,"end":57},"obj":"DT"},{"id":"T131","span":{"begin":51,"end":53},"obj":"IN"},{"id":"T130","span":{"begin":45,"end":50},"obj":"NNS"},{"id":"T129","span":{"begin":37,"end":44},"obj":"JJ"},{"id":"T128","span":{"begin":31,"end":36},"obj":"VBZ"},{"id":"T127","span":{"begin":25,"end":30},"obj":"NNP"},{"id":"T126","span":{"begin":18,"end":24},"obj":"NN"},{"id":"T125","span":{"begin":4,"end":17},"obj":"NN"},{"id":"T124","span":{"begin":0,"end":3},"obj":"DT"}],"relations":[{"id":"R110","pred":"det","subj":"T124","obj":"T126"},{"id":"R111","pred":"compound","subj":"T125","obj":"T126"},{"id":"R112","pred":"nsubj","subj":"T126","obj":"T128"},{"id":"R113","pred":"nsubj","subj":"T127","obj":"T128"},{"id":"R114","pred":"ROOT","subj":"T128","obj":"T128"},{"id":"R115","pred":"amod","subj":"T129","obj":"T130"},{"id":"R116","pred":"dobj","subj":"T130","obj":"T128"},{"id":"R117","pred":"prep","subj":"T131","obj":"T128"},{"id":"R118","pred":"det","subj":"T132","obj":"T133"},{"id":"R119","pred":"pobj","subj":"T133","obj":"T131"},{"id":"R120","pred":"prep","subj":"T134","obj":"T133"},{"id":"R121","pred":"nmod","subj":"T135","obj":"T138"},{"id":"R122","pred":"cc","subj":"T136","obj":"T135"},{"id":"R123","pred":"conj","subj":"T137","obj":"T135"},{"id":"R124","pred":"pobj","subj":"T138","obj":"T134"},{"id":"R125","pred":"punct","subj":"T139","obj":"T133"},{"id":"R126","pred":"cc","subj":"T140","obj":"T133"},{"id":"R127","pred":"amod","subj":"T141","obj":"T143"},{"id":"R128","pred":"compound","subj":"T142","obj":"T143"},{"id":"R129","pred":"conj","subj":"T143","obj":"T133"},{"id":"R130","pred":"aux","subj":"T144","obj":"T146"},{"id":"R131","pred":"auxpass","subj":"T145","obj":"T146"},{"id":"R132","pred":"conj","subj":"T146","obj":"T128"},{"id":"R133","pred":"prep","subj":"T147","obj":"T146"},{"id":"R134","pred":"amod","subj":"T148","obj":"T152"},{"id":"R135","pred":"amod","subj":"T149","obj":"T152"},{"id":"R136","pred":"cc","subj":"T150","obj":"T149"},{"id":"R137","pred":"conj","subj":"T151","obj":"T149"},{"id":"R138","pred":"pobj","subj":"T152","obj":"T147"},{"id":"R139","pred":"punct","subj":"T153","obj":"T152"},{"id":"R140","pred":"prep","subj":"T154","obj":"T152"},{"id":"R141","pred":"amod","subj":"T155","obj":"T156"},{"id":"R142","pred":"pobj","subj":"T156","obj":"T154"},{"id":"R143","pred":"punct","subj":"T157","obj":"T128"},{"id":"R144","pred":"nsubj","subj":"T158","obj":"T159"},{"id":"R145","pred":"ROOT","subj":"T159","obj":"T159"},{"id":"R146","pred":"det","subj":"T160","obj":"T163"},{"id":"R147","pred":"amod","subj":"T161","obj":"T163"},{"id":"R148","pred":"compound","subj":"T162","obj":"T163"},{"id":"R149","pred":"dobj","subj":"T163","obj":"T159"},{"id":"R150","pred":"aux","subj":"T164","obj":"T165"},{"id":"R151","pred":"relcl","subj":"T165","obj":"T163"},{"id":"R152","pred":"amod","subj":"T166","obj":"T167"},{"id":"R153","pred":"dobj","subj":"T167","obj":"T165"},{"id":"R154","pred":"prep","subj":"T168","obj":"T165"},{"id":"R155","pred":"pobj","subj":"T169","obj":"T168"},{"id":"R156","pred":"punct","subj":"T170","obj":"T165"},{"id":"R157","pred":"prep","subj":"T171","obj":"T165"},{"id":"R158","pred":"det","subj":"T172","obj":"T173"},{"id":"R159","pred":"pobj","subj":"T173","obj":"T171"},{"id":"R160","pred":"prep","subj":"T174","obj":"T173"},{"id":"R161","pred":"amod","subj":"T175","obj":"T177"},{"id":"R162","pred":"compound","subj":"T176","obj":"T177"},{"id":"R163","pred":"pobj","subj":"T177","obj":"T174"},{"id":"R164","pred":"acl","subj":"T178","obj":"T173"},{"id":"R165","pred":"dobj","subj":"T179","obj":"T178"},{"id":"R166","pred":"prep","subj":"T180","obj":"T179"},{"id":"R167","pred":"amod","subj":"T181","obj":"T182"},{"id":"R168","pred":"pobj","subj":"T182","obj":"T180"},{"id":"R169","pred":"punct","subj":"T183","obj":"T159"},{"id":"R170","pred":"advmod","subj":"T184","obj":"T187"},{"id":"R171","pred":"nsubj","subj":"T185","obj":"T187"},{"id":"R172","pred":"aux","subj":"T186","obj":"T187"},{"id":"R173","pred":"ROOT","subj":"T187","obj":"T187"},{"id":"R174","pred":"amod","subj":"T188","obj":"T191"},{"id":"R175","pred":"amod","subj":"T189","obj":"T191"},{"id":"R176","pred":"amod","subj":"T190","obj":"T191"},{"id":"R177","pred":"dobj","subj":"T191","obj":"T187"},{"id":"R178","pred":"nsubj","subj":"T192","obj":"T194"},{"id":"R179","pred":"aux","subj":"T193","obj":"T194"},{"id":"R180","pred":"relcl","subj":"T194","obj":"T191"},{"id":"R181","pred":"aux","subj":"T195","obj":"T196"},{"id":"R182","pred":"xcomp","subj":"T196","obj":"T194"},{"id":"R183","pred":"compound","subj":"T197","obj":"T198"},{"id":"R184","pred":"dobj","subj":"T198","obj":"T196"},{"id":"R185","pred":"cc","subj":"T199","obj":"T194"},{"id":"R186","pred":"nsubjpass","subj":"T200","obj":"T203"},{"id":"R187","pred":"aux","subj":"T201","obj":"T203"},{"id":"R188","pred":"auxpass","subj":"T202","obj":"T203"},{"id":"R189","pred":"conj","subj":"T203","obj":"T194"},{"id":"R190","pred":"prep","subj":"T204","obj":"T203"},{"id":"R191","pred":"det","subj":"T205","obj":"T206"},{"id":"R192","pred":"pobj","subj":"T206","obj":"T204"},{"id":"R193","pred":"prep","subj":"T207","obj":"T206"},{"id":"R194","pred":"amod","subj":"T208","obj":"T209"},{"id":"R195","pred":"pobj","subj":"T209","obj":"T207"},{"id":"R196","pred":"punct","subj":"T210","obj":"T187"}],"attributes":[{"subj":"T210","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T209","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T208","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T207","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T206","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T205","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T204","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T203","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T202","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T201","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T200","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T199","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T198","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T197","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T196","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T195","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T194","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T193","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T192","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T191","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T190","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T189","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T188","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T187","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T186","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T185","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T184","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T183","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T182","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T181","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T180","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T179","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T178","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T177","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T176","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T175","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T174","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T173","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T172","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T171","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T170","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T169","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T168","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T167","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T166","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T165","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T164","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T163","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T162","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T161","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T160","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T159","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T158","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T157","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T156","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T155","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T154","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T153","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T152","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T151","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T150","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T149","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T148","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T147","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T146","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T145","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T144","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T143","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T142","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T141","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T140","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T139","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T138","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T137","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T136","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T135","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T134","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T133","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T132","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T131","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T130","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T129","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T128","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T127","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T126","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T125","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"},{"subj":"T124","pred":"source","obj":"bionlp-st-ge-2016-spacy-parsed"}]},{"project":"pmc-enju-pas","denotations":[{"id":"T44","span":{"begin":201,"end":202},"obj":"-COMMA-"},{"id":"T43","span":{"begin":193,"end":201},"obj":"NN"},{"id":"T42","span":{"begin":180,"end":192},"obj":"JJ"},{"id":"T41","span":{"begin":176,"end":179},"obj":"CC"},{"id":"T40","span":{"begin":165,"end":175},"obj":"JJ"},{"id":"T39","span":{"begin":160,"end":164},"obj":"JJ"},{"id":"T38","span":{"begin":155,"end":159},"obj":"IN"},{"id":"T37","span":{"begin":148,"end":154},"obj":"VB"},{"id":"T36","span":{"begin":143,"end":147},"obj":"VB"},{"id":"T35","span":{"begin":139,"end":142},"obj":"VB"},{"id":"T34","span":{"begin":130,"end":138},"obj":"NN"},{"id":"T33","span":{"begin":124,"end":129},"obj":"NN"},{"id":"T32","span":{"begin":110,"end":123},"obj":"JJ"},{"id":"T31","span":{"begin":106,"end":109},"obj":"CC"},{"id":"T30","span":{"begin":104,"end":105},"obj":"-COMMA-"},{"id":"T29","span":{"begin":95,"end":104},"obj":"NN"},{"id":"T28","span":{"begin":89,"end":94},"obj":"JJ"},{"id":"T27","span":{"begin":85,"end":88},"obj":"CC"},{"id":"T26","span":{"begin":72,"end":84},"obj":"NN"},{"id":"T25","span":{"begin":69,"end":71},"obj":"IN"},{"id":"T24","span":{"begin":58,"end":68},"obj":"NN"},{"id":"T23","span":{"begin":54,"end":57},"obj":"DT"},{"id":"T22","span":{"begin":51,"end":53},"obj":"IN"},{"id":"T21","span":{"begin":45,"end":50},"obj":"NN"},{"id":"T20","span":{"begin":37,"end":44},"obj":"JJ"},{"id":"T19","span":{"begin":31,"end":36},"obj":"VB"},{"id":"T18","span":{"begin":25,"end":30},"obj":"NN"},{"id":"T17","span":{"begin":18,"end":24},"obj":"NN"},{"id":"T16","span":{"begin":4,"end":17},"obj":"NN"},{"id":"T15","span":{"begin":0,"end":3},"obj":"DT"},{"id":"T98","span":{"begin":579,"end":588},"obj":"NN"},{"id":"T97","span":{"begin":568,"end":578},"obj":"JJ"},{"id":"T96","span":{"begin":565,"end":567},"obj":"IN"},{"id":"T95","span":{"begin":552,"end":564},"obj":"NN"},{"id":"T94","span":{"begin":548,"end":551},"obj":"DT"},{"id":"T93","span":{"begin":545,"end":547},"obj":"IN"},{"id":"T92","span":{"begin":534,"end":544},"obj":"VB"},{"id":"T91","span":{"begin":529,"end":533},"obj":"VB"},{"id":"T90","span":{"begin":524,"end":528},"obj":"VB"},{"id":"T89","span":{"begin":518,"end":523},"obj":"WDT"},{"id":"T88","span":{"begin":514,"end":517},"obj":"CC"},{"id":"T87","span":{"begin":503,"end":513},"obj":"NN"},{"id":"T86","span":{"begin":497,"end":502},"obj":"NN"},{"id":"T85","span":{"begin":489,"end":496},"obj":"VB"},{"id":"T84","span":{"begin":486,"end":488},"obj":"TO"},{"id":"T83","span":{"begin":478,"end":485},"obj":"VB"},{"id":"T82","span":{"begin":473,"end":477},"obj":"VB"},{"id":"T81","span":{"begin":468,"end":472},"obj":"WDT"},{"id":"T80","span":{"begin":457,"end":467},"obj":"NN"},{"id":"T79","span":{"begin":446,"end":456},"obj":"JJ"},{"id":"T78","span":{"begin":437,"end":445},"obj":"JJ"},{"id":"T77","span":{"begin":429,"end":436},"obj":"JJ"},{"id":"T76","span":{"begin":422,"end":428},"obj":"VB"},{"id":"T75","span":{"begin":417,"end":421},"obj":"MD"},{"id":"T74","span":{"begin":414,"end":416},"obj":"PRP"},{"id":"T73","span":{"begin":409,"end":413},"obj":"RB"},{"id":"T72","span":{"begin":398,"end":407},"obj":"NN"},{"id":"T71","span":{"begin":392,"end":397},"obj":"NN"},{"id":"T70","span":{"begin":389,"end":391},"obj":"IN"},{"id":"T69","span":{"begin":377,"end":388},"obj":"NN"},{"id":"T68","span":{"begin":368,"end":376},"obj":"VB"},{"id":"T67","span":{"begin":357,"end":367},"obj":"NN"},{"id":"T66","span":{"begin":348,"end":356},"obj":"NN"},{"id":"T65","span":{"begin":339,"end":347},"obj":"JJ"},{"id":"T64","span":{"begin":336,"end":338},"obj":"IN"},{"id":"T63","span":{"begin":325,"end":335},"obj":"NN"},{"id":"T62","span":{"begin":323,"end":324},"obj":"DT"},{"id":"T61","span":{"begin":313,"end":322},"obj":"VB"},{"id":"T60","span":{"begin":311,"end":312},"obj":"-COMMA-"},{"id":"T59","span":{"begin":306,"end":311},"obj":"NN"},{"id":"T58","span":{"begin":303,"end":305},"obj":"IN"},{"id":"T57","span":{"begin":292,"end":302},"obj":"NN"},{"id":"T56","span":{"begin":286,"end":291},"obj":"NN"},{"id":"T55","span":{"begin":281,"end":285},"obj":"VB"},{"id":"T54","span":{"begin":278,"end":280},"obj":"TO"},{"id":"T53","span":{"begin":271,"end":277},"obj":"NN"},{"id":"T52","span":{"begin":263,"end":270},"obj":"NN"},{"id":"T51","span":{"begin":250,"end":262},"obj":"JJ"},{"id":"T50","span":{"begin":248,"end":249},"obj":"DT"},{"id":"T49","span":{"begin":241,"end":247},"obj":"VB"},{"id":"T48","span":{"begin":235,"end":240},"obj":"NN"},{"id":"T47","span":{"begin":224,"end":233},"obj":"NN"},{"id":"T46","span":{"begin":213,"end":223},"obj":"JJ"},{"id":"T45","span":{"begin":203,"end":212},"obj":"VB"}],"relations":[{"id":"R10","pred":"arg1Of","subj":"T18","obj":"T15"},{"id":"R11","pred":"arg1Of","subj":"T18","obj":"T16"},{"id":"R12","pred":"arg1Of","subj":"T18","obj":"T17"},{"id":"R13","pred":"arg1Of","subj":"T18","obj":"T19"},{"id":"R14","pred":"arg1Of","subj":"T19","obj":"T22"},{"id":"R15","pred":"arg1Of","subj":"T19","obj":"T31"},{"id":"R16","pred":"arg2Of","subj":"T21","obj":"T19"},{"id":"R17","pred":"arg1Of","subj":"T21","obj":"T20"},{"id":"R18","pred":"arg2Of","subj":"T24","obj":"T22"},{"id":"R19","pred":"arg1Of","subj":"T24","obj":"T23"},{"id":"R20","pred":"arg1Of","subj":"T24","obj":"T25"},{"id":"R21","pred":"arg1Of","subj":"T26","obj":"T27"},{"id":"R22","pred":"arg2Of","subj":"T27","obj":"T25"},{"id":"R23","pred":"arg2Of","subj":"T29","obj":"T27"},{"id":"R24","pred":"arg1Of","subj":"T29","obj":"T28"},{"id":"R25","pred":"arg1Of","subj":"T31","obj":"T30"},{"id":"R26","pred":"arg1Of","subj":"T34","obj":"T32"},{"id":"R27","pred":"arg1Of","subj":"T34","obj":"T33"},{"id":"R28","pred":"arg1Of","subj":"T34","obj":"T35"},{"id":"R29","pred":"arg1Of","subj":"T34","obj":"T36"},{"id":"R30","pred":"arg2Of","subj":"T34","obj":"T37"},{"id":"R31","pred":"arg2Of","subj":"T37","obj":"T31"},{"id":"R32","pred":"arg2Of","subj":"T37","obj":"T35"},{"id":"R33","pred":"arg2Of","subj":"T37","obj":"T36"},{"id":"R34","pred":"arg1Of","subj":"T37","obj":"T38"},{"id":"R35","pred":"arg1Of","subj":"T40","obj":"T41"},{"id":"R36","pred":"arg2Of","subj":"T42","obj":"T41"},{"id":"R37","pred":"arg2Of","subj":"T43","obj":"T38"},{"id":"R38","pred":"arg1Of","subj":"T43","obj":"T39"},{"id":"R39","pred":"arg1Of","subj":"T43","obj":"T40"},{"id":"R40","pred":"arg1Of","subj":"T43","obj":"T42"},{"id":"R41","pred":"arg1Of","subj":"T43","obj":"T44"},{"id":"R42","pred":"arg1Of","subj":"T43","obj":"T45"},{"id":"R43","pred":"arg2Of","subj":"T47","obj":"T45"},{"id":"R44","pred":"arg1Of","subj":"T47","obj":"T46"},{"id":"R45","pred":"arg1Of","subj":"T48","obj":"T49"},{"id":"R46","pred":"modOf","subj":"T49","obj":"T54"},{"id":"R47","pred":"arg2Of","subj":"T53","obj":"T49"},{"id":"R48","pred":"arg1Of","subj":"T53","obj":"T50"},{"id":"R49","pred":"arg1Of","subj":"T53","obj":"T51"},{"id":"R50","pred":"arg1Of","subj":"T53","obj":"T52"},{"id":"R51","pred":"arg1Of","subj":"T55","obj":"T54"},{"id":"R52","pred":"arg1Of","subj":"T55","obj":"T58"},{"id":"R53","pred":"arg2Of","subj":"T57","obj":"T55"},{"id":"R54","pred":"arg1Of","subj":"T57","obj":"T56"},{"id":"R55","pred":"arg2Of","subj":"T59","obj":"T58"},{"id":"R56","pred":"arg1Of","subj":"T59","obj":"T60"},{"id":"R57","pred":"arg1Of","subj":"T59","obj":"T61"},{"id":"R58","pred":"arg2Of","subj":"T63","obj":"T61"},{"id":"R59","pred":"arg1Of","subj":"T63","obj":"T62"},{"id":"R60","pred":"arg1Of","subj":"T63","obj":"T64"},{"id":"R61","pred":"arg2Of","subj":"T67","obj":"T64"},{"id":"R62","pred":"arg1Of","subj":"T67","obj":"T65"},{"id":"R63","pred":"arg1Of","subj":"T67","obj":"T66"},{"id":"R64","pred":"arg1Of","subj":"T67","obj":"T68"},{"id":"R65","pred":"arg2Of","subj":"T69","obj":"T68"},{"id":"R66","pred":"arg1Of","subj":"T69","obj":"T70"},{"id":"R67","pred":"arg2Of","subj":"T72","obj":"T70"},{"id":"R68","pred":"arg1Of","subj":"T72","obj":"T71"},{"id":"R69","pred":"arg1Of","subj":"T74","obj":"T75"},{"id":"R70","pred":"arg1Of","subj":"T74","obj":"T76"},{"id":"R71","pred":"arg1Of","subj":"T76","obj":"T73"},{"id":"R72","pred":"arg2Of","subj":"T76","obj":"T75"},{"id":"R73","pred":"arg2Of","subj":"T80","obj":"T76"},{"id":"R74","pred":"arg1Of","subj":"T80","obj":"T77"},{"id":"R75","pred":"arg1Of","subj":"T80","obj":"T78"},{"id":"R76","pred":"arg1Of","subj":"T80","obj":"T79"},{"id":"R77","pred":"arg1Of","subj":"T80","obj":"T81"},{"id":"R78","pred":"arg1Of","subj":"T80","obj":"T82"},{"id":"R79","pred":"arg1Of","subj":"T80","obj":"T83"},{"id":"R80","pred":"arg1Of","subj":"T80","obj":"T85"},{"id":"R81","pred":"arg1Of","subj":"T80","obj":"T89"},{"id":"R82","pred":"arg1Of","subj":"T80","obj":"T90"},{"id":"R83","pred":"arg1Of","subj":"T80","obj":"T91"},{"id":"R84","pred":"arg2Of","subj":"T80","obj":"T92"},{"id":"R85","pred":"arg2Of","subj":"T83","obj":"T82"},{"id":"R86","pred":"arg1Of","subj":"T83","obj":"T88"},{"id":"R87","pred":"arg2Of","subj":"T85","obj":"T83"},{"id":"R88","pred":"arg1Of","subj":"T85","obj":"T84"},{"id":"R89","pred":"arg2Of","subj":"T87","obj":"T85"},{"id":"R90","pred":"arg1Of","subj":"T87","obj":"T86"},{"id":"R91","pred":"arg2Of","subj":"T92","obj":"T88"},{"id":"R92","pred":"arg2Of","subj":"T92","obj":"T90"},{"id":"R93","pred":"arg2Of","subj":"T92","obj":"T91"},{"id":"R94","pred":"arg1Of","subj":"T92","obj":"T93"},{"id":"R95","pred":"arg2Of","subj":"T95","obj":"T93"},{"id":"R96","pred":"arg1Of","subj":"T95","obj":"T94"},{"id":"R97","pred":"arg1Of","subj":"T95","obj":"T96"},{"id":"R98","pred":"arg2Of","subj":"T98","obj":"T96"},{"id":"R99","pred":"arg1Of","subj":"T98","obj":"T97"}],"namespaces":[{"prefix":"_base","uri":"http://kmcs.nii.ac.jp/enju/"}],"attributes":[{"subj":"T44","pred":"source","obj":"pmc-enju-pas"},{"subj":"T43","pred":"source","obj":"pmc-enju-pas"},{"subj":"T42","pred":"source","obj":"pmc-enju-pas"},{"subj":"T41","pred":"source","obj":"pmc-enju-pas"},{"subj":"T40","pred":"source","obj":"pmc-enju-pas"},{"subj":"T39","pred":"source","obj":"pmc-enju-pas"},{"subj":"T38","pred":"source","obj":"pmc-enju-pas"},{"subj":"T37","pred":"source","obj":"pmc-enju-pas"},{"subj":"T36","pred":"source","obj":"pmc-enju-pas"},{"subj":"T35","pred":"source","obj":"pmc-enju-pas"},{"subj":"T34","pred":"source","obj":"pmc-enju-pas"},{"subj":"T33","pred":"source","obj":"pmc-enju-pas"},{"subj":"T32","pred":"source","obj":"pmc-enju-pas"},{"subj":"T31","pred":"source","obj":"pmc-enju-pas"},{"subj":"T30","pred":"source","obj":"pmc-enju-pas"},{"subj":"T29","pred":"source","obj":"pmc-enju-pas"},{"subj":"T28","pred":"source","obj":"pmc-enju-pas"},{"subj":"T27","pred":"source","obj":"pmc-enju-pas"},{"subj":"T26","pred":"source","obj":"pmc-enju-pas"},{"subj":"T25","pred":"source","obj":"pmc-enju-pas"},{"subj":"T24","pred":"source","obj":"pmc-enju-pas"},{"subj":"T23","pred":"source","obj":"pmc-enju-pas"},{"subj":"T22","pred":"source","obj":"pmc-enju-pas"},{"subj":"T21","pred":"source","obj":"pmc-enju-pas"},{"subj":"T20","pred":"source","obj":"pmc-enju-pas"},{"subj":"T19","pred":"source","obj":"pmc-enju-pas"},{"subj":"T18","pred":"source","obj":"pmc-enju-pas"},{"subj":"T17","pred":"source","obj":"pmc-enju-pas"},{"subj":"T16","pred":"source","obj":"pmc-enju-pas"},{"subj":"T15","pred":"source","obj":"pmc-enju-pas"},{"subj":"T98","pred":"source","obj":"pmc-enju-pas"},{"subj":"T97","pred":"source","obj":"pmc-enju-pas"},{"subj":"T96","pred":"source","obj":"pmc-enju-pas"},{"subj":"T95","pred":"source","obj":"pmc-enju-pas"},{"subj":"T94","pred":"source","obj":"pmc-enju-pas"},{"subj":"T93","pred":"source","obj":"pmc-enju-pas"},{"subj":"T92","pred":"source","obj":"pmc-enju-pas"},{"subj":"T91","pred":"source","obj":"pmc-enju-pas"},{"subj":"T90","pred":"source","obj":"pmc-enju-pas"},{"subj":"T89","pred":"source","obj":"pmc-enju-pas"},{"subj":"T88","pred":"source","obj":"pmc-enju-pas"},{"subj":"T87","pred":"source","obj":"pmc-enju-pas"},{"subj":"T86","pred":"source","obj":"pmc-enju-pas"},{"subj":"T85","pred":"source","obj":"pmc-enju-pas"},{"subj":"T84","pred":"source","obj":"pmc-enju-pas"},{"subj":"T83","pred":"source","obj":"pmc-enju-pas"},{"subj":"T82","pred":"source","obj":"pmc-enju-pas"},{"subj":"T81","pred":"source","obj":"pmc-enju-pas"},{"subj":"T80","pred":"source","obj":"pmc-enju-pas"},{"subj":"T79","pred":"source","obj":"pmc-enju-pas"},{"subj":"T78","pred":"source","obj":"pmc-enju-pas"},{"subj":"T77","pred":"source","obj":"pmc-enju-pas"},{"subj":"T76","pred":"source","obj":"pmc-enju-pas"},{"subj":"T75","pred":"source","obj":"pmc-enju-pas"},{"subj":"T74","pred":"source","obj":"pmc-enju-pas"},{"subj":"T73","pred":"source","obj":"pmc-enju-pas"},{"subj":"T72","pred":"source","obj":"pmc-enju-pas"},{"subj":"T71","pred":"source","obj":"pmc-enju-pas"},{"subj":"T70","pred":"source","obj":"pmc-enju-pas"},{"subj":"T69","pred":"source","obj":"pmc-enju-pas"},{"subj":"T68","pred":"source","obj":"pmc-enju-pas"},{"subj":"T67","pred":"source","obj":"pmc-enju-pas"},{"subj":"T66","pred":"source","obj":"pmc-enju-pas"},{"subj":"T65","pred":"source","obj":"pmc-enju-pas"},{"subj":"T64","pred":"source","obj":"pmc-enju-pas"},{"subj":"T63","pred":"source","obj":"pmc-enju-pas"},{"subj":"T62","pred":"source","obj":"pmc-enju-pas"},{"subj":"T61","pred":"source","obj":"pmc-enju-pas"},{"subj":"T60","pred":"source","obj":"pmc-enju-pas"},{"subj":"T59","pred":"source","obj":"pmc-enju-pas"},{"subj":"T58","pred":"source","obj":"pmc-enju-pas"},{"subj":"T57","pred":"source","obj":"pmc-enju-pas"},{"subj":"T56","pred":"source","obj":"pmc-enju-pas"},{"subj":"T55","pred":"source","obj":"pmc-enju-pas"},{"subj":"T54","pred":"source","obj":"pmc-enju-pas"},{"subj":"T53","pred":"source","obj":"pmc-enju-pas"},{"subj":"T52","pred":"source","obj":"pmc-enju-pas"},{"subj":"T51","pred":"source","obj":"pmc-enju-pas"},{"subj":"T50","pred":"source","obj":"pmc-enju-pas"},{"subj":"T49","pred":"source","obj":"pmc-enju-pas"},{"subj":"T48","pred":"source","obj":"pmc-enju-pas"},{"subj":"T47","pred":"source","obj":"pmc-enju-pas"},{"subj":"T46","pred":"source","obj":"pmc-enju-pas"},{"subj":"T45","pred":"source","obj":"pmc-enju-pas"}]},{"project":"GO-BP","denotations":[{"id":"T100","span":{"begin":58,"end":68},"obj":"http://purl.obolibrary.org/obo/GO_0065007"},{"id":"T101","span":{"begin":4,"end":17},"obj":"http://purl.obolibrary.org/obo/GO_0006351"},{"id":"T102","span":{"begin":72,"end":84},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T103","span":{"begin":286,"end":302},"obj":"http://purl.obolibrary.org/obo/GO_0038061"},{"id":"T104","span":{"begin":497,"end":513},"obj":"http://purl.obolibrary.org/obo/GO_0038061"},{"id":"T105","span":{"begin":292,"end":302},"obj":"http://purl.obolibrary.org/obo/GO_0023052"},{"id":"T106","span":{"begin":503,"end":513},"obj":"http://purl.obolibrary.org/obo/GO_0023052"},{"id":"T107","span":{"begin":552,"end":564},"obj":"http://purl.obolibrary.org/obo/GO_0009405"}],"attributes":[{"subj":"T100","pred":"source","obj":"GO-BP"},{"subj":"T101","pred":"source","obj":"GO-BP"},{"subj":"T102","pred":"source","obj":"GO-BP"},{"subj":"T103","pred":"source","obj":"GO-BP"},{"subj":"T104","pred":"source","obj":"GO-BP"},{"subj":"T105","pred":"source","obj":"GO-BP"},{"subj":"T106","pred":"source","obj":"GO-BP"},{"subj":"T107","pred":"source","obj":"GO-BP"}]},{"project":"sentences","denotations":[{"id":"T2","span":{"begin":0,"end":234},"obj":"Sentence"},{"id":"T3","span":{"begin":235,"end":408},"obj":"Sentence"},{"id":"T4","span":{"begin":409,"end":589},"obj":"Sentence"},{"id":"T3","span":{"begin":0,"end":234},"obj":"Sentence"},{"id":"T4","span":{"begin":235,"end":408},"obj":"Sentence"},{"id":"T5","span":{"begin":409,"end":589},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T2","pred":"source","obj":"sentences"},{"subj":"T3","pred":"source","obj":"sentences"},{"subj":"T4","pred":"source","obj":"sentences"},{"subj":"T3","pred":"source","obj":"sentences"},{"subj":"T4","pred":"source","obj":"sentences"},{"subj":"T5","pred":"source","obj":"sentences"}]},{"project":"ICD10","denotations":[{"id":"T109","span":{"begin":213,"end":233},"obj":"http://purl.bioontology.org/ontology/ICD10/M06.9"},{"id":"T110","span":{"begin":568,"end":588},"obj":"http://purl.bioontology.org/ontology/ICD10/M06.9"},{"id":"T112","span":{"begin":224,"end":233},"obj":"http://purl.bioontology.org/ontology/ICD10/M13.9"},{"id":"T113","span":{"begin":579,"end":588},"obj":"http://purl.bioontology.org/ontology/ICD10/M13.9"}],"attributes":[{"subj":"T109","pred":"source","obj":"ICD10"},{"subj":"T110","pred":"source","obj":"ICD10"},{"subj":"T112","pred":"source","obj":"ICD10"},{"subj":"T113","pred":"source","obj":"ICD10"}]},{"project":"bionlp-st-ge-2016-test-ihmc","denotations":[{"id":"T239","span":{"begin":489,"end":502},"obj":"Regulation"},{"id":"T238","span":{"begin":110,"end":154},"obj":"Binding"},{"id":"T237","span":{"begin":124,"end":129},"obj":"Protein"},{"id":"T235","span":{"begin":286,"end":302},"obj":"Protein"},{"id":"T234","span":{"begin":25,"end":30},"obj":"Protein"},{"id":"T233","span":{"begin":235,"end":240},"obj":"Entity"},{"id":"T232","span":{"begin":497,"end":502},"obj":"Protein"},{"id":"T231","span":{"begin":392,"end":397},"obj":"Protein"}],"relations":[{"id":"R201","pred":"themeOf","subj":"T232","obj":"T239"}],"attributes":[{"subj":"T239","pred":"source","obj":"bionlp-st-ge-2016-test-ihmc"},{"subj":"T238","pred":"source","obj":"bionlp-st-ge-2016-test-ihmc"},{"subj":"T237","pred":"source","obj":"bionlp-st-ge-2016-test-ihmc"},{"subj":"T235","pred":"source","obj":"bionlp-st-ge-2016-test-ihmc"},{"subj":"T234","pred":"source","obj":"bionlp-st-ge-2016-test-ihmc"},{"subj":"T233","pred":"source","obj":"bionlp-st-ge-2016-test-ihmc"},{"subj":"T232","pred":"source","obj":"bionlp-st-ge-2016-test-ihmc"},{"subj":"T231","pred":"source","obj":"bionlp-st-ge-2016-test-ihmc"}]},{"project":"bionlp-st-ge-2016-test-tees","denotations":[{"id":"T215","span":{"begin":4,"end":30},"obj":"Protein"},{"id":"T216","span":{"begin":124,"end":129},"obj":"Protein"},{"id":"T217","span":{"begin":286,"end":291},"obj":"Protein"},{"id":"T218","span":{"begin":392,"end":397},"obj":"Protein"},{"id":"T219","span":{"begin":497,"end":502},"obj":"Protein"},{"id":"T220","span":{"begin":489,"end":496},"obj":"Regulation"}],"relations":[{"id":"R205","pred":"themeOf","subj":"T219","obj":"T220"}],"attributes":[{"subj":"T215","pred":"source","obj":"bionlp-st-ge-2016-test-tees"},{"subj":"T216","pred":"source","obj":"bionlp-st-ge-2016-test-tees"},{"subj":"T217","pred":"source","obj":"bionlp-st-ge-2016-test-tees"},{"subj":"T218","pred":"source","obj":"bionlp-st-ge-2016-test-tees"},{"subj":"T219","pred":"source","obj":"bionlp-st-ge-2016-test-tees"},{"subj":"T220","pred":"source","obj":"bionlp-st-ge-2016-test-tees"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"bionlp-st-ge-2016-spacy-parsed","color":"#e493ec","default":true},{"id":"pmc-enju-pas","color":"#93ecca"},{"id":"GO-BP","color":"#ecb093"},{"id":"sentences","color":"#9593ec"},{"id":"ICD10","color":"#aaec93"},{"id":"bionlp-st-ge-2016-test-ihmc","color":"#ec93c4"},{"id":"bionlp-st-ge-2016-test-tees","color":"#93deec"}]}]}}