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PMC:3218875 / 7645-8529 JSONTXT

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testone

Id Subject Object Predicate Lexical cue
T3956 535-546 Protein_catabolism denotes degradation
T3955 447-462 Phosphorylation denotes phosphorylation
T3864 829-833 Protein denotes IKK1
T3863 815-819 Protein denotes NEMO
T3862 806-810 Protein denotes IKK2
T3861 749-753 Protein denotes IKKγ
T3860 728-732 Protein denotes NEMO
T3859 701-726 Protein denotes NF-κB essential modulator
T3858 668-672 Protein denotes IKKβ
T3857 659-663 Protein denotes IKKα
T3856 639-643 Protein denotes IKK2
T3855 630-634 Protein denotes IKK1
T3854 185-190 Protein denotes RANKL
T3853 163-166 Protein denotes TNF

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T6194 883-884 . denotes .
T6193 882-883 NNP denotes ]
T6192 880-882 CD denotes 21
T6191 879-880 NNP denotes [
T6190 868-878 NN denotes activation
T6189 862-867 NN denotes NF-κB
T6161 733-734 : denotes -
T6160 728-732 SYM denotes NEMO
T6159 727-728 -LRB- denotes (
T6158 717-726 NN denotes modulator
T6157 707-716 JJ denotes essential
T6156 701-706 NN denotes NF-κB
T6155 693-700 NN denotes subunit
T6154 682-692 JJ denotes regulatory
T6153 678-681 DT denotes the
T6152 674-677 CC denotes and
T6151 672-673 -RRB- denotes )
T6150 668-672 NNP denotes IKKβ
T6149 664-667 CC denotes and
T6148 659-663 NNP denotes IKKα
T6147 656-658 IN denotes as
T6146 650-655 VBN denotes known
T6145 645-649 RB denotes also
T6144 644-645 -LRB- denotes (
T6143 639-643 NNP denotes IKK2
T6142 635-638 CC denotes and
T6141 630-634 NNP denotes IKK1
T6140 621-629 NNS denotes subunits
T6139 611-620 JJ denotes catalytic
T6138 607-610 CD denotes two
T6137 603-606 DT denotes the
T6136 600-602 IN denotes of
T6135 590-599 VBN denotes comprised
T6134 587-589 VBZ denotes is
T6133 579-586 NN denotes complex
T6132 575-578 NNP denotes IKK
T6131 571-574 DT denotes The
T6130 569-570 . denotes .
T6129 568-569 NNP denotes ]
T6128 566-568 CD denotes 20
T6127 565-566 NNP denotes [
T6126 554-564 JJ denotes proteasome
T6125 550-553 DT denotes the
T6124 547-549 IN denotes by
T6123 535-546 NN denotes degradation
T6122 531-534 CC denotes and
T6121 508-530 NN denotes K48-polyubiquitination
T6120 504-507 PRP$ denotes its
T6119 501-503 TO denotes to
T6118 493-500 VBG denotes leading
T6117 485-492 NN denotes protein
T6116 481-484 NNP denotes IκB
T6115 470-480 JJ denotes inhibitory
T6114 466-469 DT denotes the
T6113 463-465 IN denotes of
T6112 447-462 NN denotes phosphorylation
T6111 438-446 VBZ denotes mediates
T6110 432-437 WDT denotes which
T6109 430-431 , denotes ,
T6108 423-430 JJ denotes complex
T6107 421-422 -RRB- denotes )
T6106 418-421 NNP denotes IKK
T6105 417-418 -LRB- denotes (
T6104 410-416 NN denotes kinase
T6103 406-409 NNP denotes IκB
T6102 402-405 DT denotes the
T6101 399-401 IN denotes of
T6100 388-398 NN denotes activation
T6099 384-387 DT denotes the
T6098 381-383 IN denotes in
T6097 372-380 NN denotes converge
T6096 361-371 RB denotes ultimately
T6095 357-360 CC denotes but
T6094 355-356 , denotes ,
T6093 347-355 JJ denotes specific
T6092 338-346 NN denotes receptor
T6091 332-337 RB denotes often
T6090 328-331 VBP denotes are
T6089 323-327 WDT denotes that
T6088 310-322 NNS denotes interactions
T6087 294-309 NN denotes protein-protein
T6086 285-293 JJ denotes proximal
T6085 282-284 IN denotes of
T6084 272-281 NN denotes formation
T6083 268-271 DT denotes the
T6082 259-267 VBZ denotes requires
T6081 249-258 NNS denotes receptors
T6080 239-248 JJ denotes different
T6079 236-238 IN denotes by
T6078 226-235 VBN denotes initiated
T6077 215-225 JJ denotes signalling
T6076 209-214 JJ denotes NF-κB
T6075 207-208 . denotes .
T6074 200-207 NNS denotes ligands
T6073 196-199 NNP denotes TLR
T6072 192-195 CC denotes and
T6071 190-191 , denotes ,
T6070 185-190 NNP denotes RANKL
T6069 183-184 , denotes ,
T6068 175-183 NNS denotes antigens
T6067 173-174 , denotes ,
T6066 172-173 -RRB- denotes )
T6065 168-172 NNP denotes IL-1
T6064 166-167 , denotes ,
T6063 163-166 NNP denotes TNF
T6062 161-162 , denotes ,
T6061 154-161 NN denotes example
T6060 150-153 IN denotes for
T6059 149-150 -LRB- denotes (
T6058 139-148 NNS denotes cytokines
T6057 123-138 JJ denotes proinflammatory
T6056 113-122 VBG denotes including
T6055 105-112 NNS denotes stimuli
T6054 100-104 JJ denotes many
T6053 97-99 IN denotes by
T6052 87-96 VBN denotes triggered
T6051 84-86 VBZ denotes is
T6050 80-83 CC denotes and
T6049 78-79 , denotes ,
T6048 70-78 NN denotes immunity
T6047 61-69 JJ denotes adaptive
T6046 57-60 CC denotes and
T6045 50-56 NN denotes innate
T6044 47-49 IN denotes in
T6043 42-46 NN denotes role
T6042 36-41 JJ denotes major
T6041 34-35 DT denotes a
T6040 28-33 VBZ denotes plays
T6039 20-27 NN denotes pathway
T6038 14-19 NN denotes NF-κB
T6037 4-13 JJ denotes canonical
T6036 0-3 DT denotes The
T6188 852-861 JJ denotes canonical
T6187 848-851 IN denotes for
T6186 839-847 VBN denotes required
T6185 835-838 VBP denotes are
T6184 833-834 , denotes ,
T6183 829-833 NNP denotes IKK1
T6182 825-828 RB denotes not
T6181 821-824 CC denotes but
T6180 819-820 , denotes ,
T6179 815-819 NNP denotes NEMO
T6178 811-814 CC denotes and
T6177 806-810 NNP denotes IKK2
T6176 801-805 IN denotes that
T6175 794-800 VBD denotes showed
T6174 782-793 NNS denotes experiments
T6173 772-781 VBG denotes targeting
T6172 767-771 NNP denotes Gene
T6171 765-766 . denotes .
T6170 764-765 -RRB- denotes )
T6169 763-764 CD denotes 1
T6168 756-762 NN denotes Figure
T6167 755-756 -LRB- denotes (
T6166 753-754 -RRB- denotes )
T6165 749-753 NNP denotes IKKγ
T6164 746-748 IN denotes as
T6163 740-745 VBN denotes known
T6162 735-739 RB denotes also
R4088 T6057 T6058 amod proinflammatory,cytokines
R4091 T6058 T6056 pobj cytokines,including
R4092 T6059 T6058 punct (,cytokines
R4099 T6060 T6058 prep for,cytokines
R4102 T6061 T6060 pobj example,for
R4105 T6062 T6068 punct ",",antigens
R4107 T6036 T6039 det The,pathway
R4108 T6037 T6039 amod canonical,pathway
R4109 T6063 T6068 nmod TNF,antigens
R4110 T6038 T6039 compound NF-κB,pathway
R4111 T6039 T6040 nsubj pathway,plays
R4112 T6040 T6040 ROOT plays,plays
R4113 T6041 T6043 det a,role
R4114 T6064 T6063 punct ",",TNF
R4115 T6042 T6043 amod major,role
R4116 T6043 T6040 dobj role,plays
R4117 T6044 T6043 prep in,role
R4118 T6065 T6063 conj IL-1,TNF
R4119 T6045 T6048 amod innate,immunity
R4120 T6046 T6045 cc and,innate
R4121 T6047 T6045 conj adaptive,innate
R4122 T6066 T6065 punct ),IL-1
R4123 T6048 T6044 pobj immunity,in
R4124 T6049 T6040 punct ",",plays
R4125 T6050 T6040 cc and,plays
R4126 T6067 T6065 punct ",",IL-1
R4127 T6051 T6052 auxpass is,triggered
R4128 T6052 T6040 conj triggered,plays
R4129 T6053 T6052 agent by,triggered
R4130 T6068 T6058 conj antigens,cytokines
R4131 T6069 T6068 punct ",",antigens
R4132 T6070 T6068 conj RANKL,antigens
R4133 T6071 T6070 punct ",",RANKL
R4134 T6151 T6150 punct ),IKKβ
R4135 T6072 T6070 cc and,RANKL
R4136 T6152 T6146 cc and,known
R4137 T6153 T6155 det the,subunit
R4138 T6073 T6070 conj TLR,RANKL
R4139 T6154 T6155 amod regulatory,subunit
R4140 T6155 T6146 conj subunit,known
R4141 T6156 T6158 nmod NF-κB,modulator
R4142 T6074 T6070 conj ligands,RANKL
R4143 T6157 T6158 amod essential,modulator
R4144 T6158 T6155 appos modulator,subunit
R4145 T6159 T6163 punct (,known
R4146 T6160 T6163 punct NEMO,known
R4147 T6161 T6163 punct -,known
R4148 T6162 T6163 advmod also,known
R4149 T6075 T6040 punct .,plays
R4150 T6163 T6155 acl known,subunit
R4151 T6164 T6163 prep as,known
R4152 T6165 T6164 pobj IKKγ,as
R4153 T6076 T6077 amod NF-κB,signalling
R4154 T6166 T6140 punct ),subunits
R4155 T6167 T6168 punct (,Figure
R4156 T6077 T6082 nsubj signalling,requires
R4157 T6168 T6140 appos Figure,subunits
R4158 T6169 T6168 nummod 1,Figure
R4159 T6078 T6077 acl initiated,signalling
R4160 T6170 T6168 punct ),Figure
R4161 T6171 T6135 punct .,comprised
R4162 T6172 T6174 compound Gene,experiments
R4163 T6173 T6174 compound targeting,experiments
R4164 T6079 T6078 agent by,initiated
R4165 T6174 T6175 nsubj experiments,showed
R4166 T6175 T6175 ROOT showed,showed
R4167 T6176 T6186 mark that,required
R4168 T6080 T6081 amod different,receptors
R4169 T6177 T6186 nsubjpass IKK2,required
R4170 T6178 T6177 cc and,IKK2
R4171 T6081 T6079 pobj receptors,by
R4172 T6082 T6082 ROOT requires,requires
R4173 T6179 T6177 conj NEMO,IKK2
R4174 T6180 T6177 punct ",",IKK2
R4175 T6181 T6177 cc but,IKK2
R4176 T6083 T6084 det the,formation
R4177 T6182 T6183 neg not,IKK1
R4178 T6183 T6177 conj IKK1,IKK2
R4179 T6184 T6186 punct ",",required
R4180 T6185 T6186 auxpass are,required
R4181 T6084 T6082 dobj formation,requires
R4182 T6186 T6175 ccomp required,showed
R4183 T6085 T6084 prep of,formation
R4184 T6187 T6186 prep for,required
R4185 T6086 T6088 amod proximal,interactions
R4186 T6188 T6190 amod canonical,activation
R4187 T6087 T6088 compound protein-protein,interactions
R4188 T6189 T6190 compound NF-κB,activation
R4189 T6190 T6187 pobj activation,for
R4190 T6088 T6085 pobj interactions,of
R4191 T6191 T6193 nmod [,]
R4192 T6192 T6193 nummod 21,]
R4193 T6193 T6190 appos ],activation
R4194 T6194 T6175 punct .,showed
R4197 T6089 T6090 nsubj that,are
R4201 T6090 T6088 relcl are,interactions
R4205 T6091 T6090 advmod often,are
R4209 T6092 T6093 npadvmod receptor,specific
R4212 T6093 T6090 acomp specific,are
R4216 T6094 T6082 punct ",",requires
R4220 T6095 T6082 cc but,requires
R4224 T6096 T6097 advmod ultimately,converge
R4228 T6097 T6082 conj converge,requires
R4232 T6098 T6097 prep in,converge
R4236 T6099 T6100 det the,activation
R4240 T6100 T6098 pobj activation,in
R4247 T6101 T6100 prep of,activation
R4252 T6102 T6104 det the,kinase
R4255 T6103 T6104 compound IκB,kinase
R4259 T6104 T6101 pobj kinase,of
R4262 T6105 T6106 punct (,IKK
R4265 T6106 T6104 appos IKK,kinase
R4266 T6107 T6106 punct ),IKK
R4267 T6108 T6104 conj complex,kinase
R4268 T6109 T6104 punct ",",kinase
R4271 T6110 T6111 nsubj which,mediates
R4275 T6111 T6104 relcl mediates,kinase
R4279 T6112 T6111 dobj phosphorylation,mediates
R4281 T6113 T6112 prep of,phosphorylation
R4282 T6114 T6117 det the,protein
R4285 T6115 T6117 amod inhibitory,protein
R4289 T6116 T6117 compound IκB,protein
R4292 T6117 T6113 pobj protein,of
R4298 T6118 T6117 acl leading,protein
R4302 T6119 T6118 prep to,leading
R4307 T6120 T6121 poss its,K48-polyubiquitination
R4310 T6121 T6119 pobj K48-polyubiquitination,to
R4314 T6122 T6121 cc and,K48-polyubiquitination
R4318 T6123 T6121 conj degradation,K48-polyubiquitination
R4321 T6124 T6121 prep by,K48-polyubiquitination
R4325 T6125 T6129 det the,]
R4329 T6126 T6127 compound proteasome,[
R4332 T6127 T6129 nmod [,]
R4336 T6128 T6129 nummod 20,]
R4340 T6129 T6124 pobj ],by
R4343 T6130 T6082 punct .,requires
R4350 T6131 T6133 det The,complex
R4354 T6132 T6133 compound IKK,complex
R4358 T6133 T6135 nsubjpass complex,comprised
R4361 T6134 T6135 auxpass is,comprised
R4365 T6135 T6135 ROOT comprised,comprised
R4369 T6136 T6135 prep of,comprised
R4372 T6137 T6140 det the,subunits
R4376 T6138 T6140 nummod two,subunits
R4379 T6139 T6140 amod catalytic,subunits
R4384 T6140 T6136 pobj subunits,of
R4387 T6141 T6140 appos IKK1,subunits
R4389 T6142 T6141 cc and,IKK1
R4390 T6143 T6141 conj IKK2,IKK1
R4393 T6144 T6146 punct (,known
R4400 T6145 T6146 advmod also,known
R4402 T6146 T6141 parataxis known,IKK1
R4403 T6147 T6146 prep as,known
R4404 T6148 T6147 pobj IKKα,as
R4407 T6149 T6148 cc and,IKKα
R4411 T6150 T6148 conj IKKβ,IKKα
R4071 T6054 T6055 amod many,stimuli
R4079 T6055 T6053 pobj stimuli,by
R4084 T6056 T6055 prep including,stimuli

DLUT931

Id Subject Object Predicate Lexical cue
T7195 839-847 Positive_regulation denotes required
T7108 829-833 Protein denotes IKK1
T7107 815-819 Protein denotes NEMO
T7106 806-810 Protein denotes IKK2
T7105 749-753 Protein denotes IKKγ
T7104 728-732 Protein denotes NEMO
T7103 701-726 Protein denotes NF-κB essential modulator
T7102 668-672 Protein denotes IKKβ
T7101 659-663 Protein denotes IKKα
T7100 639-643 Protein denotes IKK2
T7099 630-634 Protein denotes IKK1
T7098 185-190 Protein denotes RANKL
T7097 163-166 Protein denotes TNF
R4973 T7106 T7195 themeOf IKK2,required
R4974 T7107 T7195 themeOf NEMO,required
R4975 T7108 T7195 causeOf IKK1,required
R4976 T7108 T7195 causeOf IKK1,required

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T6898 815-819 http://www.uniprot.org/uniprot/Q9Y6K9 denotes NEMO
T6897 728-732 http://www.uniprot.org/uniprot/Q9Y6K9 denotes NEMO
T6896 668-672 http://www.uniprot.org/uniprot/O14920 denotes IKKβ
T6895 639-643 http://www.uniprot.org/uniprot/O14920 denotes IKK2
T6892 829-833 http://www.uniprot.org/uniprot/Q60680-2 denotes IKK1
T6891 630-634 http://www.uniprot.org/uniprot/Q60680-2 denotes IKK1
T6890 406-416 http://www.uniprot.org/uniprot/Q60680-2 denotes IκB kinase
T6887 829-833 http://www.uniprot.org/uniprot/O15111 denotes IKK1
T6886 630-634 http://www.uniprot.org/uniprot/O15111 denotes IKK1
T6885 406-416 http://www.uniprot.org/uniprot/O15111 denotes IκB kinase
T6876 163-166 http://www.uniprot.org/uniprot/P01375 denotes TNF

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T4485 829-833 Protein denotes IKK1
T4484 815-819 Protein denotes NEMO
T4483 806-810 Protein denotes IKK2
T4482 749-753 Protein denotes IKKγ
T4481 728-732 Protein denotes NEMO
T4480 701-726 Protein denotes NF-κB essential modulator
T4479 668-672 Protein denotes IKKβ
T4478 659-663 Protein denotes IKKα
T4477 639-643 Protein denotes IKK2
T4476 630-634 Protein denotes IKK1
T4475 185-190 Protein denotes RANKL
T4474 163-166 Protein denotes TNF

2_test

Id Subject Object Predicate Lexical cue
21639951-21135871-4289449 566-568 21135871 denotes 20
21639951-16470223-4289450 880-882 16470223 denotes 21

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T4841 882-883 -RRB- denotes ]
T4840 880-882 CD denotes 21
T4839 879-880 -LRB- denotes [
T4838 868-878 NN denotes activation
T4837 862-867 NN denotes NF-κB
T4836 852-861 JJ denotes canonical
T4835 848-851 IN denotes for
T4834 839-847 VB denotes required
T4833 835-838 VB denotes are
T4832 833-834 -COMMA- denotes ,
T4831 829-833 NN denotes IKK1
T4830 825-828 RB denotes not
T4829 821-824 CC denotes but
T4828 819-820 -COMMA- denotes ,
T4827 815-819 NN denotes NEMO
T4826 811-814 CC denotes and
T4825 806-810 NN denotes IKK2
T4824 801-805 IN denotes that
T4823 794-800 VB denotes showed
T4822 782-793 NN denotes experiments
T4821 772-781 VB denotes targeting
T4820 767-771 NN denotes Gene
T4819 764-765 -RRB- denotes )
T4818 763-764 CD denotes 1
T4817 756-762 NN denotes Figure
T4816 755-756 -LRB- denotes (
T4815 753-754 -RRB- denotes )
T4814 749-753 NN denotes IKKγ
T4813 746-748 IN denotes as
T4812 740-745 VB denotes known
T4811 735-739 RB denotes also
T4810 733-734 -COLON- denotes -
T4809 728-732 NN denotes NEMO
T4808 727-728 -LRB- denotes (
T4807 717-726 NN denotes modulator
T4806 707-716 JJ denotes essential
T4805 701-706 NN denotes NF-κB
T4804 693-700 NN denotes subunit
T4803 682-692 JJ denotes regulatory
T4802 678-681 DT denotes the
T4801 674-677 CC denotes and
T4800 672-673 -RRB- denotes )
T4799 668-672 NN denotes IKKβ
T4798 664-667 CC denotes and
T4797 659-663 NN denotes IKKα
T4796 656-658 IN denotes as
T4795 650-655 VB denotes known
T4794 645-649 RB denotes also
T4793 644-645 -LRB- denotes (
T4792 639-643 NN denotes IKK2
T4791 635-638 CC denotes and
T4790 630-634 NN denotes IKK1
T4789 621-629 NN denotes subunits
T4788 611-620 JJ denotes catalytic
T4787 607-610 CD denotes two
T4786 603-606 DT denotes the
T4785 600-602 IN denotes of
T4784 590-599 VB denotes comprised
T4783 587-589 VB denotes is
T4782 579-586 NN denotes complex
T4781 575-578 NN denotes IKK
T4780 571-574 DT denotes The
T4779 568-569 -RRB- denotes ]
T4778 566-568 CD denotes 20
T4777 565-566 -LRB- denotes [
T4776 554-564 NN denotes proteasome
T4775 550-553 DT denotes the
T4774 547-549 IN denotes by
T4773 535-546 NN denotes degradation
T4772 531-534 CC denotes and
T4771 508-530 NN denotes K48-polyubiquitination
T4770 504-507 PRP-DOLLAR- denotes its
T4769 501-503 TO denotes to
T4768 493-500 VB denotes leading
T4767 485-492 NN denotes protein
T4766 481-484 NN denotes IκB
T4765 470-480 JJ denotes inhibitory
T4764 466-469 DT denotes the
T4763 463-465 IN denotes of
T4762 447-462 NN denotes phosphorylation
T4761 438-446 VB denotes mediates
T4760 432-437 WDT denotes which
T4759 430-431 -COMMA- denotes ,
T4758 423-430 NN denotes complex
T4757 421-422 -RRB- denotes )
T4756 418-421 NN denotes IKK
T4755 417-418 -LRB- denotes (
T4754 410-416 NN denotes kinase
T4753 406-409 NN denotes IκB
T4752 402-405 DT denotes the
T4751 399-401 IN denotes of
T4750 388-398 NN denotes activation
T4749 384-387 DT denotes the
T4748 381-383 IN denotes in
T4747 372-380 VB denotes converge
T4746 361-371 RB denotes ultimately
T4745 357-360 CC denotes but
T4744 355-356 -COMMA- denotes ,
T4743 347-355 JJ denotes specific
T4742 338-346 NN denotes receptor
T4741 332-337 RB denotes often
T4740 328-331 VB denotes are
T4739 323-327 WDT denotes that
T4738 310-322 NN denotes interactions
T4737 294-309 JJ denotes protein-protein
T4736 285-293 JJ denotes proximal
T4735 282-284 IN denotes of
T4734 272-281 NN denotes formation
T4733 268-271 DT denotes the
T4732 259-267 VB denotes requires
T4731 249-258 NN denotes receptors
T4730 239-248 JJ denotes different
T4729 236-238 IN denotes by
T4728 226-235 VB denotes initiated
T4727 215-225 NN denotes signalling
T4726 209-214 NN denotes NF-κB
T4725 200-207 NN denotes ligands
T4724 196-199 NN denotes TLR
T4723 192-195 CC denotes and
T4722 190-191 -COMMA- denotes ,
T4721 185-190 NN denotes RANKL
T4720 183-184 -COMMA- denotes ,
T4719 175-183 NN denotes antigens
T4718 173-174 -COMMA- denotes ,
T4717 172-173 -RRB- denotes )
T4716 168-172 NN denotes IL-1
T4715 166-167 -COMMA- denotes ,
T4714 163-166 NN denotes TNF
T4713 161-162 -COMMA- denotes ,
T4712 154-161 NN denotes example
T4711 150-153 IN denotes for
T4710 149-150 -LRB- denotes (
T4709 139-148 NN denotes cytokines
T4708 123-138 JJ denotes proinflammatory
T4707 113-122 VB denotes including
T4706 105-112 NN denotes stimuli
T4705 100-104 JJ denotes many
T4704 97-99 IN denotes by
T4703 87-96 VB denotes triggered
T4702 84-86 VB denotes is
T4701 80-83 CC denotes and
T4700 78-79 -COMMA- denotes ,
T4699 70-78 NN denotes immunity
T4698 61-69 JJ denotes adaptive
T4697 57-60 CC denotes and
T4696 50-56 JJ denotes innate
T4695 47-49 IN denotes in
T4694 42-46 NN denotes role
T4693 36-41 JJ denotes major
T4692 34-35 DT denotes a
T4691 28-33 VB denotes plays
T4690 20-27 NN denotes pathway
T4689 14-19 NN denotes NF-κB
T4688 4-13 JJ denotes canonical
T4687 0-3 DT denotes The
R3149 T4690 T4687 arg1Of pathway,The
R3150 T4690 T4688 arg1Of pathway,canonical
R3151 T4690 T4689 arg1Of pathway,NF-κB
R3152 T4690 T4691 arg1Of pathway,plays
R3153 T4690 T4702 arg1Of pathway,is
R3154 T4690 T4703 arg2Of pathway,triggered
R3155 T4691 T4695 arg1Of plays,in
R3156 T4691 T4701 arg1Of plays,and
R3157 T4694 T4691 arg2Of role,plays
R3158 T4694 T4692 arg1Of role,a
R3159 T4694 T4693 arg1Of role,major
R3160 T4696 T4697 arg1Of innate,and
R3161 T4698 T4697 arg2Of adaptive,and
R3162 T4699 T4695 arg2Of immunity,in
R3163 T4699 T4696 arg1Of immunity,innate
R3164 T4699 T4698 arg1Of immunity,adaptive
R3165 T4701 T4700 arg1Of and,","
R3166 T4703 T4701 arg2Of triggered,and
R3167 T4703 T4702 arg2Of triggered,is
R3168 T4706 T4703 arg1Of stimuli,triggered
R3169 T4706 T4704 arg2Of stimuli,by
R3170 T4706 T4705 arg1Of stimuli,many
R3171 T4706 T4707 arg1Of stimuli,including
R3172 T4709 T4708 arg1Of cytokines,proinflammatory
R3173 T4709 T4710 arg1Of cytokines,(
R3174 T4709 T4718 arg1Of cytokines,","
R3175 T4711 T4710 arg2Of for,(
R3176 T4712 T4713 arg1Of example,","
R3177 T4713 T4715 arg1Of ",",","
R3178 T4714 T4713 arg2Of TNF,","
R3179 T4715 T4711 arg2Of ",",for
R3180 T4716 T4715 arg2Of IL-1,","
R3181 T4717 T4710 arg3Of ),(
R3182 T4718 T4707 arg2Of ",",including
R3183 T4719 T4720 arg1Of antigens,","
R3184 T4720 T4723 arg1Of ",",and
R3185 T4721 T4720 arg2Of RANKL,","
R3186 T4723 T4718 arg2Of and,","
R3187 T4723 T4722 arg1Of and,","
R3188 T4725 T4723 arg2Of ligands,and
R3189 T4725 T4724 arg1Of ligands,TLR
R3190 T4727 T4726 arg1Of signalling,NF-κB
R3191 T4727 T4728 arg2Of signalling,initiated
R3192 T4727 T4732 arg1Of signalling,requires
R3193 T4731 T4728 arg1Of receptors,initiated
R3194 T4731 T4729 arg2Of receptors,by
R3195 T4731 T4730 arg1Of receptors,different
R3196 T4734 T4732 arg2Of formation,requires
R3197 T4734 T4733 arg1Of formation,the
R3198 T4734 T4735 arg1Of formation,of
R3199 T4734 T4759 arg1Of formation,","
R3200 T4734 T4760 arg1Of formation,which
R3201 T4734 T4761 arg1Of formation,mediates
R3202 T4738 T4735 arg2Of interactions,of
R3203 T4738 T4736 arg1Of interactions,proximal
R3204 T4738 T4737 arg1Of interactions,protein-protein
R3205 T4738 T4739 arg1Of interactions,that
R3206 T4738 T4740 arg1Of interactions,are
R3207 T4738 T4743 arg1Of interactions,specific
R3208 T4738 T4747 arg1Of interactions,converge
R3209 T4740 T4741 arg1Of are,often
R3210 T4740 T4745 arg1Of are,but
R3211 T4743 T4740 arg2Of specific,are
R3212 T4743 T4742 arg1Of specific,receptor
R3213 T4745 T4744 arg1Of but,","
R3214 T4747 T4745 arg2Of converge,but
R3215 T4747 T4746 arg1Of converge,ultimately
R3216 T4747 T4748 arg1Of converge,in
R3217 T4750 T4748 arg2Of activation,in
R3218 T4750 T4749 arg1Of activation,the
R3219 T4750 T4751 arg1Of activation,of
R3220 T4754 T4753 arg1Of kinase,IκB
R3221 T4754 T4755 arg1Of kinase,(
R3222 T4756 T4755 arg2Of IKK,(
R3223 T4757 T4755 arg3Of ),(
R3224 T4758 T4751 arg2Of complex,of
R3225 T4758 T4752 arg1Of complex,the
R3226 T4758 T4754 arg1Of complex,kinase
R3227 T4762 T4761 arg2Of phosphorylation,mediates
R3228 T4762 T4763 arg1Of phosphorylation,of
R3229 T4767 T4763 arg2Of protein,of
R3230 T4767 T4764 arg1Of protein,the
R3231 T4767 T4765 arg1Of protein,inhibitory
R3232 T4767 T4766 arg1Of protein,IκB
R3233 T4767 T4768 arg1Of protein,leading
R3234 T4768 T4769 arg1Of leading,to
R3235 T4768 T4777 arg1Of leading,[
R3236 T4771 T4772 arg1Of K48-polyubiquitination,and
R3237 T4772 T4769 arg2Of and,to
R3238 T4772 T4770 arg1Of and,its
R3239 T4772 T4774 arg1Of and,by
R3240 T4773 T4772 arg2Of degradation,and
R3241 T4776 T4774 arg2Of proteasome,by
R3242 T4776 T4775 arg1Of proteasome,the
R3243 T4778 T4777 arg2Of 20,[
R3244 T4779 T4777 arg3Of ],[
R3245 T4782 T4780 arg1Of complex,The
R3246 T4782 T4781 arg1Of complex,IKK
R3247 T4782 T4783 arg1Of complex,is
R3248 T4782 T4784 arg2Of complex,comprised
R3249 T4784 T4783 arg2Of comprised,is
R3250 T4784 T4785 arg1Of comprised,of
R3251 T4784 T4816 arg1Of comprised,(
R3252 T4789 T4787 arg1Of subunits,two
R3253 T4789 T4788 arg1Of subunits,catalytic
R3254 T4790 T4791 arg1Of IKK1,and
R3255 T4791 T4786 arg1Of and,the
R3256 T4791 T4789 arg1Of and,subunits
R3257 T4791 T4793 arg1Of and,(
R3258 T4791 T4801 arg1Of and,and
R3259 T4792 T4791 arg2Of IKK2,and
R3260 T4795 T4793 arg2Of known,(
R3261 T4795 T4794 arg1Of known,also
R3262 T4795 T4796 arg1Of known,as
R3263 T4797 T4798 arg1Of IKKα,and
R3264 T4798 T4796 arg2Of and,as
R3265 T4799 T4798 arg2Of IKKβ,and
R3266 T4800 T4793 arg3Of ),(
R3267 T4801 T4785 arg2Of and,of
R3268 T4807 T4801 arg2Of modulator,and
R3269 T4807 T4802 arg1Of modulator,the
R3270 T4807 T4803 arg1Of modulator,regulatory
R3271 T4807 T4804 arg1Of modulator,subunit
R3272 T4807 T4805 arg1Of modulator,NF-κB
R3273 T4807 T4806 arg1Of modulator,essential
R3274 T4807 T4808 arg1Of modulator,(
R3275 T4809 T4808 arg2Of NEMO,(
R3276 T4809 T4810 arg1Of NEMO,-
R3277 T4809 T4812 arg2Of NEMO,known
R3278 T4812 T4811 arg1Of known,also
R3279 T4812 T4813 arg1Of known,as
R3280 T4814 T4813 arg2Of IKKγ,as
R3281 T4815 T4808 arg3Of ),(
R3282 T4817 T4816 arg2Of Figure,(
R3283 T4817 T4818 arg1Of Figure,1
R3284 T4819 T4816 arg3Of ),(
R3285 T4820 T4821 arg1Of Gene,targeting
R3286 T4820 T4823 arg1Of Gene,showed
R3287 T4822 T4821 arg2Of experiments,targeting
R3288 T4825 T4826 arg1Of IKK2,and
R3289 T4826 T4829 arg1Of and,but
R3290 T4827 T4826 arg2Of NEMO,and
R3291 T4829 T4828 arg1Of but,","
R3292 T4829 T4830 arg1Of but,not
R3293 T4829 T4833 arg1Of but,are
R3294 T4829 T4834 arg2Of but,required
R3295 T4831 T4829 arg2Of IKK1,but
R3296 T4834 T4823 arg2Of required,showed
R3297 T4834 T4824 arg1Of required,that
R3298 T4834 T4832 arg1Of required,","
R3299 T4834 T4833 arg2Of required,are
R3300 T4834 T4835 arg1Of required,for
R3301 T4834 T4839 arg1Of required,[
R3302 T4838 T4835 arg2Of activation,for
R3303 T4838 T4836 arg1Of activation,canonical
R3304 T4838 T4837 arg1Of activation,NF-κB
R3305 T4840 T4839 arg2Of 21,[
R3306 T4841 T4839 arg3Of ],[

GO-BP

Id Subject Object Predicate Lexical cue
T5527 862-878 http://purl.obolibrary.org/obo/GO_0051092 denotes NF-κB activation
T5525 535-564 http://purl.obolibrary.org/obo/GO_1903009 denotes degradation by the proteasome
T5521 535-546 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T5518 447-462 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T5515 575-578 http://purl.obolibrary.org/obo/GO_0008384 denotes IKK
T5514 418-421 http://purl.obolibrary.org/obo/GO_0008384 denotes IKK
T5513 272-281 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T5504 215-225 http://purl.obolibrary.org/obo/GO_0023052 denotes signalling
T5499 209-225 http://purl.obolibrary.org/obo/GO_0038061 denotes NF-κB signalling

GO-MF

Id Subject Object Predicate Lexical cue
T5615 575-578 http://purl.obolibrary.org/obo/GO_0008384 denotes IKK
T5614 418-421 http://purl.obolibrary.org/obo/GO_0008384 denotes IKK
T5612 168-172 http://purl.obolibrary.org/obo/GO_0005149 denotes IL-1
T5610 200-207 http://purl.obolibrary.org/obo/GO_0005488 denotes ligands

GO-CC

Id Subject Object Predicate Lexical cue
T5686 554-564 http://purl.obolibrary.org/obo/GO_0000502 denotes proteasome
T5685 575-586 http://purl.obolibrary.org/obo/GO_0008385 denotes IKK complex
T5684 418-430 http://purl.obolibrary.org/obo/GO_0008385 denotes IKK) complex

sentences

Id Subject Object Predicate Lexical cue
T4243 767-884 Sentence denotes Gene targeting experiments showed that IKK2 and NEMO, but not IKK1, are required for canonical NF-κB activation [21].
T4242 571-766 Sentence denotes The IKK complex is comprised of the two catalytic subunits IKK1 and IKK2 (also known as IKKα and IKKβ) and the regulatory subunit NF-κB essential modulator (NEMO - also known as IKKγ) (Figure 1).
T4241 209-570 Sentence denotes NF-κB signalling initiated by different receptors requires the formation of proximal protein-protein interactions that are often receptor specific, but ultimately converge in the activation of the IκB kinase (IKK) complex, which mediates phosphorylation of the inhibitory IκB protein leading to its K48-polyubiquitination and degradation by the proteasome [20].
T4240 0-208 Sentence denotes The canonical NF-κB pathway plays a major role in innate and adaptive immunity, and is triggered by many stimuli including proinflammatory cytokines (for example, TNF, IL-1), antigens, RANKL, and TLR ligands.
T42 0-208 Sentence denotes The canonical NF-κB pathway plays a major role in innate and adaptive immunity, and is triggered by many stimuli including proinflammatory cytokines (for example, TNF, IL-1), antigens, RANKL, and TLR ligands.
T43 209-570 Sentence denotes NF-κB signalling initiated by different receptors requires the formation of proximal protein-protein interactions that are often receptor specific, but ultimately converge in the activation of the IκB kinase (IKK) complex, which mediates phosphorylation of the inhibitory IκB protein leading to its K48-polyubiquitination and degradation by the proteasome [20].
T44 571-766 Sentence denotes The IKK complex is comprised of the two catalytic subunits IKK1 and IKK2 (also known as IKKα and IKKβ) and the regulatory subunit NF-κB essential modulator (NEMO - also known as IKKγ) (Figure 1).
T45 767-884 Sentence denotes Gene targeting experiments showed that IKK2 and NEMO, but not IKK1, are required for canonical NF-κB activation [21].

simple1

Id Subject Object Predicate Lexical cue
T5814 829-833 Protein denotes IKK1
T5813 815-819 Protein denotes NEMO
T5812 806-810 Protein denotes IKK2
T5811 749-753 Protein denotes IKKγ
T5810 728-732 Protein denotes NEMO
T5809 701-726 Protein denotes NF-κB essential modulator
T5808 668-672 Protein denotes IKKβ
T5807 659-663 Protein denotes IKKα
T5806 639-643 Protein denotes IKK2
T5805 630-634 Protein denotes IKK1
T5804 185-190 Protein denotes RANKL
T5803 163-166 Protein denotes TNF

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T7843 829-833 Protein denotes IKK1
T7842 815-819 Protein denotes NEMO
T7841 806-810 Protein denotes IKK2
T7840 749-753 Protein denotes IKKγ
T7839 728-732 Protein denotes NEMO
T7838 701-726 Protein denotes NF-κB essential modulator
T7837 668-672 Protein denotes IKKβ
T7836 659-663 Protein denotes IKKα
T7835 639-643 Protein denotes IKK2
T7834 630-634 Protein denotes IKK1
T7833 185-190 Protein denotes RANKL
T7832 163-166 Protein denotes TNF

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T7053 839-847 Positive_regulation denotes required
T6966 829-833 Protein denotes IKK1
T6965 815-819 Protein denotes NEMO
T6964 806-810 Protein denotes IKK2
T6963 749-753 Protein denotes IKKγ
T6962 728-732 Protein denotes NEMO
T6961 701-726 Protein denotes NF-κB essential modulator
T6960 668-672 Protein denotes IKKβ
T6959 659-663 Protein denotes IKKα
T6958 639-643 Protein denotes IKK2
T6957 630-634 Protein denotes IKK1
T6956 185-190 Protein denotes RANKL
T6955 163-166 Protein denotes TNF
R4903 T6964 T7053 causeOf IKK2,required
R4905 T6965 T7053 themeOf NEMO,required
R4906 T6965 T7053 themeOf NEMO,required
R4907 T6966 T7053 causeOf IKK1,required

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T8204 432-462 Regulation denotes which mediates phosphorylation
T8180 852-883 Positive_regulation denotes canonical NF-κB activation [21]
T8165 668-672 Protein denotes IKKβ
T8164 767-793 Protein denotes Gene targeting experiments
T8163 659-663 Protein denotes IKKα
T8162 209-258 Protein denotes NF-κB signalling initiated by different receptors
T8157 815-819 Protein denotes NEMO
T8154 504-530 Entity denotes its K48-polyubiquitination
T8148 123-173 Protein denotes proinflammatory cytokines (for example, TNF, IL-1)
T8147 185-190 Protein denotes RANKL
T8146 399-431 Entity denotes of the IκB kinase (IKK) complex,
T8134 338-355 Protein denotes receptor specific
T8114 163-167 Protein denotes TNF,
T8113 175-183 Entity denotes antigens
T8108 829-833 Protein denotes IKK1
T8098 862-867 Protein denotes NF-κB
T8089 639-643 Protein denotes IKK2
T8078 547-564 Entity denotes by the proteasome
T8076 579-586 Entity denotes complex
T8066 728-753 Protein denotes NEMO - also known as IKKγ
T8061 603-634 Protein denotes the two catalytic subunits IKK1
T8058 302-309 Protein denotes protein
T8055 0-27 Protein denotes The canonical NF-κB pathway
T8053 163-172 Protein denotes TNF, IL-1
T8040 485-569 Protein denotes protein leading to its K48-polyubiquitination and degradation by the proteasome [20]
T8036 399-431 Protein denotes of the IκB kinase (IKK) complex,
T8034 678-754 Protein denotes the regulatory subunit NF-κB essential modulator (NEMO - also known as IKKγ)
T8010 236-258 Protein denotes by different receptors
T8008 749-753 Protein denotes IKKγ
T8006 801-810 Protein denotes that IKK2
T7998 282-355 Protein denotes of proximal protein-protein interactions that are often receptor specific
T7972 196-207 Entity denotes TLR ligands
R5545 T8098 T8180 themeOf NF-κB,canonical NF-κB activation [21]

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T7415 839-847 Positive_regulation denotes required
T7414 839-847 Positive_regulation denotes required
T7413 839-847 Positive_regulation denotes required
T7412 868-878 Positive_regulation denotes activation
T7411 862-867 Protein denotes NF-κB
T7410 829-833 Protein denotes IKK1
T7409 815-819 Protein denotes NEMO
T7408 806-810 Protein denotes IKK2
T7407 590-599 Gene_expression denotes comprised
T7406 590-599 Gene_expression denotes comprised
T7405 590-599 Gene_expression denotes comprised
T7404 693-706 Protein denotes subunit NF-κB
T7403 668-672 Protein denotes IKKβ
T7402 659-663 Protein denotes IKKα
T7401 639-643 Protein denotes IKK2
T7400 630-634 Protein denotes IKK1
T7399 575-586 Protein denotes IKK complex
T7398 438-446 Positive_regulation denotes mediates
T7397 438-446 Positive_regulation denotes mediates
T7396 438-446 Positive_regulation denotes mediates
T7395 388-398 Positive_regulation denotes activation
T7394 388-398 Positive_regulation denotes activation
T7393 535-546 Protein_catabolism denotes degradation
T7392 535-546 Protein_catabolism denotes degradation
T7391 447-462 Phosphorylation denotes phosphorylation
T7390 423-430 Entity denotes complex
T7389 481-492 Protein denotes IκB protein
T7388 418-421 Protein denotes IKK
T7387 406-416 Protein denotes IκB kinase
T7386 209-214 Protein denotes NF-κB
T7385 196-199 Protein denotes TLR
T7384 185-190 Protein denotes RANKL
T7383 163-166 Protein denotes TNF
T7382 14-19 Protein denotes NF-κB
R5141 T7387 T7394 themeOf IκB kinase,activation
R5144 T7388 T7392 themeOf IKK,degradation
R5145 T7388 T7395 themeOf IKK,activation
R5146 T7389 T7391 themeOf IκB protein,phosphorylation
R5148 T7389 T7393 themeOf IκB protein,degradation
R5149 T7390 T7387 SiteParent complex,IκB kinase
R5153 T7390 T7388 SiteParent complex,IKK
R5154 T7391 T7396 themeOf phosphorylation,mediates
R5155 T7392 T7397 themeOf degradation,mediates
R5158 T7393 T7398 themeOf degradation,mediates
R5160 T7394 T7390 Site activation,complex
R5161 T7395 T7390 Site activation,complex
R5163 T7396 T7388 Cause mediates,IKK
R5168 T7397 T7388 Cause mediates,IKK
R5171 T7398 T7388 Cause mediates,IKK
R5172 T7399 T7405 themeOf IKK complex,comprised
R5173 T7400 T7406 themeOf IKK1,comprised
R5174 T7401 T7407 themeOf IKK2,comprised
R5175 T7411 T7412 themeOf NF-κB,activation
R5176 T7412 T7413 themeOf activation,required
R5178 T7412 T7414 themeOf activation,required
R5180 T7412 T7415 themeOf activation,required
R5182 T7413 T7408 Cause required,IKK2
R5186 T7414 T7409 Cause required,NEMO
R5187 T7415 T7410 Cause required,IKK1

test3

Id Subject Object Predicate Lexical cue
T4125 829-833 Protein denotes IKK1
T4124 815-819 Protein denotes NEMO
T4123 806-810 Protein denotes IKK2
T4122 749-753 Protein denotes IKKγ
T4121 728-732 Protein denotes NEMO
T4120 701-726 Protein denotes NF-κB essential modulator
T4119 668-672 Protein denotes IKKβ
T4118 659-663 Protein denotes IKKα
T4117 639-643 Protein denotes IKK2
T4116 630-634 Protein denotes IKK1
T4115 535-546 Protein_catabolism denotes degradation
T4114 447-462 Phosphorylation denotes phosphorylation
T4113 438-446 Positive_regulation denotes mediates
T4112 185-190 Protein denotes RANKL
T4111 163-166 Protein denotes TNF
T4008 829-833 Protein denotes IKK1
T4007 815-819 Protein denotes NEMO
T4006 806-810 Protein denotes IKK2
T4005 749-753 Protein denotes IKKγ
T4004 728-732 Protein denotes NEMO
T4003 701-726 Protein denotes NF-κB essential modulator
T4002 668-672 Protein denotes IKKβ
T4001 659-663 Protein denotes IKKα
T4000 639-643 Protein denotes IKK2
T3999 630-634 Protein denotes IKK1
T3998 185-190 Protein denotes RANKL
T3997 163-166 Protein denotes TNF
R2844 T4114 T4113 themeOf phosphorylation,mediates
R2845 T4121 T4120 equivalentTo NEMO,NF-κB essential modulator