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PMC:3218875 / 14-752 JSONTXT

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bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T116 6-8 IN denotes of
T117 9-14 NNP denotes NF-κB
T118 15-18 CC denotes and
T119 19-22 PRP$ denotes its
T120 23-34 NN denotes involvement
T121 35-37 IN denotes in
T122 38-48 JJ denotes rheumatoid
T123 49-58 NNS denotes arthritis
T833 684-693 NNS denotes arthritis
T832 673-683 JJ denotes Rheumatoid
T210 657-658 . denotes .
T209 648-657 NNS denotes arthritis
T208 637-647 JJ denotes rheumatoid
T207 634-636 IN denotes of
T206 621-633 NN denotes pathogenesis
T205 617-620 DT denotes the
T204 614-616 IN denotes in
T203 603-613 VBN denotes implicated
T202 598-602 VBN denotes been
T201 593-597 VBP denotes have
T200 587-592 WDT denotes which
T199 583-586 CC denotes and
T198 572-582 NN denotes signalling
T197 566-571 JJ denotes NF-κB
T196 558-565 VB denotes control
T195 555-557 TO denotes to
T194 547-554 VBN denotes evolved
T193 542-546 VBP denotes have
T192 537-541 WDT denotes that
T191 526-536 NNS denotes mechanisms
T190 515-525 JJ denotes regulatory
T189 506-514 JJ denotes negative
T188 498-505 JJ denotes various
T187 491-497 VB denotes review
T186 486-490 MD denotes will
T185 483-485 PRP denotes we
T184 478-482 RB denotes Here
T183 476-477 . denotes .
T182 467-476 NNS denotes responses
T181 461-466 JJ denotes NF-κB
T180 458-460 IN denotes of
T179 446-457 NN denotes termination
T178 437-445 VBG denotes ensuring
T177 426-436 NNS denotes regulators
T176 417-425 NN denotes feedback
T175 408-416 JJ denotes negative
T174 405-407 IN denotes of
T173 394-404 NN denotes repertoire
T172 392-393 DT denotes a
T171 382-391 VBG denotes including
T170 380-381 , denotes ,
T169 375-380 NN denotes check
T168 372-374 IN denotes in
T167 361-371 NN denotes signalling
T166 355-360 JJ denotes NF-κB
T165 350-354 VB denotes keep
T164 347-349 TO denotes to
T163 340-346 NN denotes system
T162 332-339 NN denotes control
T161 319-331 JJ denotes multilayered
T160 317-318 DT denotes a
T159 310-316 VBP denotes employ
T158 304-309 NNS denotes Cells
T157 302-303 . denotes .
T156 293-302 NNS denotes arthritis
T155 282-292 JJ denotes rheumatoid
T154 272-281 VBG denotes including
T153 270-271 , denotes ,
T152 262-270 NNS denotes diseases
T151 249-261 JJ denotes inflammatory
T150 245-248 CC denotes and
T149 234-244 JJ denotes autoimmune
T148 229-233 JJ denotes many
T147 224-228 IN denotes with
T146 217-223 VBN denotes linked
T145 212-216 VBN denotes been
T144 208-211 VBZ denotes has
T143 199-207 NN denotes activity
T142 193-198 NN denotes NF-κB
T141 179-192 JJ denotes inappropriate
T140 175-178 CC denotes and
T139 173-174 , denotes ,
T138 164-173 NNS denotes responses
T137 158-163 NN denotes mmune
T136 154-157 CC denotes and
T135 141-153 NN denotes inflammation
T134 138-140 IN denotes of
T133 127-137 NN denotes regulation
T132 123-126 DT denotes the
T131 120-122 IN denotes in
T130 114-119 NNS denotes roles
T129 106-113 JJ denotes crucial
T128 100-105 VBZ denotes plays
T127 94-99 NNP denotes NF-κB
T126 87-93 NN denotes factor
T125 73-86 NN denotes transcription
T124 69-72 DT denotes The
T841 718-730 JJ denotes inflammatory
T840 711-717 JJ denotes common
T839 706-710 RBS denotes most
T838 702-705 DT denotes the
T837 699-701 VBZ denotes is
T836 697-698 -RRB- denotes )
T835 695-697 NNP denotes RA
T834 694-695 -LRB- denotes (
R103 T117 T116 pobj NF-κB,of
R104 T118 T117 cc and,NF-κB
R105 T119 T120 poss its,involvement
R107 T121 T120 prep in,involvement
R108 T122 T123 amod rheumatoid,arthritis
R109 T123 T121 pobj arthritis,in
R110 T124 T126 det The,factor
R111 T125 T126 compound transcription,factor
R112 T126 T128 nsubj factor,plays
R113 T127 T128 nsubj NF-κB,plays
R114 T128 T128 ROOT plays,plays
R115 T129 T130 amod crucial,roles
R116 T130 T128 dobj roles,plays
R117 T131 T128 prep in,plays
R118 T132 T133 det the,regulation
R119 T133 T131 pobj regulation,in
R120 T134 T133 prep of,regulation
R121 T135 T138 nmod inflammation,responses
R122 T136 T135 cc and,inflammation
R123 T137 T135 conj mmune,inflammation
R124 T138 T134 pobj responses,of
R125 T139 T133 punct ",",regulation
R126 T140 T133 cc and,regulation
R127 T141 T143 amod inappropriate,activity
R128 T142 T143 compound NF-κB,activity
R129 T143 T133 conj activity,regulation
R130 T144 T146 aux has,linked
R131 T145 T146 auxpass been,linked
R132 T146 T128 conj linked,plays
R133 T147 T146 prep with,linked
R134 T148 T152 amod many,diseases
R135 T149 T152 amod autoimmune,diseases
R136 T150 T149 cc and,autoimmune
R137 T151 T149 conj inflammatory,autoimmune
R138 T152 T147 pobj diseases,with
R139 T153 T152 punct ",",diseases
R140 T154 T152 prep including,diseases
R141 T155 T156 amod rheumatoid,arthritis
R142 T156 T154 pobj arthritis,including
R143 T157 T128 punct .,plays
R144 T158 T159 nsubj Cells,employ
R145 T159 T159 ROOT employ,employ
R146 T160 T163 det a,system
R147 T161 T163 amod multilayered,system
R148 T162 T163 compound control,system
R149 T163 T159 dobj system,employ
R150 T164 T165 aux to,keep
R151 T165 T163 relcl keep,system
R152 T166 T167 amod NF-κB,signalling
R153 T167 T165 dobj signalling,keep
R154 T168 T165 prep in,keep
R155 T169 T168 pobj check,in
R156 T170 T165 punct ",",keep
R157 T171 T165 prep including,keep
R158 T172 T173 det a,repertoire
R159 T173 T171 pobj repertoire,including
R160 T174 T173 prep of,repertoire
R161 T175 T177 amod negative,regulators
R162 T176 T177 compound feedback,regulators
R163 T177 T174 pobj regulators,of
R164 T178 T173 acl ensuring,repertoire
R165 T179 T178 dobj termination,ensuring
R166 T180 T179 prep of,termination
R167 T181 T182 amod NF-κB,responses
R168 T182 T180 pobj responses,of
R169 T183 T159 punct .,employ
R170 T184 T187 advmod Here,review
R171 T185 T187 nsubj we,review
R172 T186 T187 aux will,review
R173 T187 T187 ROOT review,review
R174 T188 T191 amod various,mechanisms
R175 T189 T191 amod negative,mechanisms
R176 T190 T191 amod regulatory,mechanisms
R177 T191 T187 dobj mechanisms,review
R178 T192 T194 nsubj that,evolved
R179 T193 T194 aux have,evolved
R180 T194 T191 relcl evolved,mechanisms
R181 T195 T196 aux to,control
R182 T196 T194 xcomp control,evolved
R183 T197 T198 compound NF-κB,signalling
R184 T198 T196 dobj signalling,control
R185 T199 T194 cc and,evolved
R186 T200 T203 nsubjpass which,implicated
R187 T201 T203 aux have,implicated
R188 T202 T203 auxpass been,implicated
R189 T203 T194 conj implicated,evolved
R190 T204 T203 prep in,implicated
R191 T205 T206 det the,pathogenesis
R192 T206 T204 pobj pathogenesis,in
R193 T207 T206 prep of,pathogenesis
R194 T208 T209 amod rheumatoid,arthritis
R195 T209 T207 pobj arthritis,of
R196 T210 T187 punct .,review
R642 T832 T833 amod Rheumatoid,arthritis
R643 T833 T837 nsubj arthritis,is
R644 T834 T833 punct (,arthritis
R645 T835 T833 appos RA,arthritis
R646 T836 T833 punct ),arthritis
R647 T837 T837 ROOT is,is
R649 T839 T840 advmod most,common

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T7 6-8 IN denotes of
T8 9-14 NN denotes NF-κB
T9 15-18 CC denotes and
T10 19-22 PRP-DOLLAR- denotes its
T11 23-34 NN denotes involvement
T12 35-37 IN denotes in
T13 38-48 JJ denotes rheumatoid
T14 49-58 NN denotes arthritis
T44 270-271 -COMMA- denotes ,
T43 262-270 NN denotes diseases
T42 249-261 JJ denotes inflammatory
T41 245-248 CC denotes and
T40 234-244 JJ denotes autoimmune
T39 229-233 JJ denotes many
T38 224-228 IN denotes with
T37 217-223 VB denotes linked
T36 212-216 VB denotes been
T35 208-211 VB denotes has
T34 199-207 NN denotes activity
T33 193-198 NN denotes NF-κB
T32 179-192 JJ denotes inappropriate
T31 175-178 CC denotes and
T30 173-174 -COMMA- denotes ,
T29 164-173 NN denotes responses
T28 158-163 JJ denotes mmune
T27 154-157 CC denotes and
T26 141-153 NN denotes inflammation
T25 138-140 IN denotes of
T24 127-137 NN denotes regulation
T23 123-126 DT denotes the
T22 120-122 IN denotes in
T21 114-119 NN denotes roles
T20 106-113 JJ denotes crucial
T19 100-105 VB denotes plays
T18 94-99 NN denotes NF-κB
T17 87-93 NN denotes factor
T16 73-86 NN denotes transcription
T15 69-72 DT denotes The
T98 648-657 NN denotes arthritis
T97 637-647 JJ denotes rheumatoid
T96 634-636 IN denotes of
T95 621-633 NN denotes pathogenesis
T94 617-620 DT denotes the
T93 614-616 IN denotes in
T92 603-613 VB denotes implicated
T91 598-602 VB denotes been
T90 593-597 VB denotes have
T89 587-592 WDT denotes which
T88 583-586 CC denotes and
T87 572-582 NN denotes signalling
T86 566-571 NN denotes NF-κB
T85 558-565 VB denotes control
T84 555-557 TO denotes to
T83 547-554 VB denotes evolved
T82 542-546 VB denotes have
T81 537-541 WDT denotes that
T80 526-536 NN denotes mechanisms
T79 515-525 JJ denotes regulatory
T78 506-514 JJ denotes negative
T77 498-505 JJ denotes various
T76 491-497 VB denotes review
T75 486-490 MD denotes will
T74 483-485 PRP denotes we
T73 478-482 RB denotes Here
T72 467-476 NN denotes responses
T71 461-466 NN denotes NF-κB
T70 458-460 IN denotes of
T69 446-457 NN denotes termination
T68 437-445 VB denotes ensuring
T67 426-436 NN denotes regulators
T66 417-425 NN denotes feedback
T65 408-416 JJ denotes negative
T64 405-407 IN denotes of
T63 394-404 NN denotes repertoire
T62 392-393 DT denotes a
T61 382-391 VB denotes including
T60 380-381 -COMMA- denotes ,
T59 375-380 NN denotes check
T58 372-374 IN denotes in
T57 361-371 NN denotes signalling
T56 355-360 NN denotes NF-κB
T55 350-354 VB denotes keep
T54 347-349 TO denotes to
T53 340-346 NN denotes system
T52 332-339 NN denotes control
T51 319-331 JJ denotes multilayered
T50 317-318 DT denotes a
T49 310-316 VB denotes employ
T48 304-309 NN denotes Cells
T47 293-302 NN denotes arthritis
T46 282-292 JJ denotes rheumatoid
T45 272-281 VB denotes including
T383 718-730 JJ denotes inflammatory
T382 711-717 JJ denotes common
T381 706-710 RB denotes most
T380 702-705 DT denotes the
T379 699-701 VB denotes is
T378 697-698 -RRB- denotes )
T377 695-697 NN denotes RA
T376 694-695 -LRB- denotes (
T375 684-693 NN denotes arthritis
T374 673-683 JJ denotes Rheumatoid
R4 T8 T7 arg2Of NF-κB,of
R5 T11 T9 arg2Of involvement,and
R6 T11 T10 arg1Of involvement,its
R7 T11 T12 arg1Of involvement,in
R8 T14 T12 arg2Of arthritis,in
R9 T14 T13 arg1Of arthritis,rheumatoid
R10 T18 T15 arg1Of NF-κB,The
R11 T18 T16 arg1Of NF-κB,transcription
R12 T18 T17 arg1Of NF-κB,factor
R13 T18 T19 arg1Of NF-κB,plays
R14 T19 T22 arg1Of plays,in
R15 T19 T31 arg1Of plays,and
R16 T21 T19 arg2Of roles,plays
R17 T21 T20 arg1Of roles,crucial
R18 T24 T22 arg2Of regulation,in
R19 T24 T23 arg1Of regulation,the
R20 T24 T25 arg1Of regulation,of
R21 T26 T27 arg1Of inflammation,and
R22 T27 T25 arg2Of and,of
R23 T29 T27 arg2Of responses,and
R24 T29 T28 arg1Of responses,mmune
R25 T31 T30 arg1Of and,","
R26 T34 T32 arg1Of activity,inappropriate
R27 T34 T33 arg1Of activity,NF-κB
R28 T34 T35 arg1Of activity,has
R29 T34 T36 arg1Of activity,been
R30 T34 T37 arg2Of activity,linked
R31 T37 T31 arg2Of linked,and
R32 T37 T35 arg2Of linked,has
R33 T37 T36 arg2Of linked,been
R34 T37 T38 arg1Of linked,with
R35 T40 T41 arg1Of autoimmune,and
R36 T42 T41 arg2Of inflammatory,and
R37 T43 T38 arg2Of diseases,with
R38 T43 T39 arg1Of diseases,many
R39 T43 T40 arg1Of diseases,autoimmune
R40 T43 T42 arg1Of diseases,inflammatory
R41 T43 T44 arg1Of diseases,","
R42 T43 T45 arg1Of diseases,including
R43 T47 T45 arg2Of arthritis,including
R44 T47 T46 arg1Of arthritis,rheumatoid
R45 T48 T49 arg1Of Cells,employ
R46 T49 T54 modOf employ,to
R47 T53 T49 arg2Of system,employ
R48 T53 T50 arg1Of system,a
R49 T53 T51 arg1Of system,multilayered
R50 T53 T52 arg1Of system,control
R51 T55 T54 arg1Of keep,to
R52 T55 T58 arg1Of keep,in
R53 T57 T55 arg2Of signalling,keep
R54 T57 T56 arg1Of signalling,NF-κB
R55 T59 T58 arg2Of check,in
R56 T59 T60 arg1Of check,","
R57 T59 T61 arg1Of check,including
R58 T63 T61 arg2Of repertoire,including
R59 T63 T62 arg1Of repertoire,a
R60 T63 T64 arg1Of repertoire,of
R61 T67 T64 arg2Of regulators,of
R62 T67 T65 arg1Of regulators,negative
R63 T67 T66 arg1Of regulators,feedback
R64 T67 T68 arg1Of regulators,ensuring
R65 T69 T68 arg2Of termination,ensuring
R66 T69 T70 arg1Of termination,of
R67 T72 T70 arg2Of responses,of
R68 T72 T71 arg1Of responses,NF-κB
R69 T74 T75 arg1Of we,will
R70 T74 T76 arg1Of we,review
R71 T76 T73 arg1Of review,Here
R72 T76 T75 arg2Of review,will
R73 T80 T76 arg2Of mechanisms,review
R74 T80 T77 arg1Of mechanisms,various
R75 T80 T78 arg1Of mechanisms,negative
R76 T80 T79 arg1Of mechanisms,regulatory
R77 T80 T81 arg1Of mechanisms,that
R78 T80 T82 arg1Of mechanisms,have
R79 T80 T83 arg1Of mechanisms,evolved
R80 T80 T85 arg1Of mechanisms,control
R81 T80 T89 arg1Of mechanisms,which
R82 T80 T90 arg1Of mechanisms,have
R83 T80 T91 arg1Of mechanisms,been
R84 T80 T92 arg2Of mechanisms,implicated
R85 T83 T82 arg2Of evolved,have
R86 T83 T88 arg1Of evolved,and
R87 T85 T83 arg2Of control,evolved
R88 T85 T84 arg1Of control,to
R89 T87 T85 arg2Of signalling,control
R90 T87 T86 arg1Of signalling,NF-κB
R91 T92 T88 arg2Of implicated,and
R92 T92 T90 arg2Of implicated,have
R93 T92 T91 arg2Of implicated,been
R94 T92 T93 arg1Of implicated,in
R95 T95 T93 arg2Of pathogenesis,in
R96 T95 T94 arg1Of pathogenesis,the
R97 T95 T96 arg1Of pathogenesis,of
R98 T98 T96 arg2Of arthritis,of
R99 T98 T97 arg1Of arthritis,rheumatoid
R233 T375 T374 arg1Of arthritis,Rheumatoid
R234 T375 T376 arg1Of arthritis,(
R235 T375 T379 arg1Of arthritis,is
R237 T377 T376 arg2Of RA,(
R238 T378 T376 arg3Of ),(
R241 T382 T381 arg1Of common,most

GO-BP

Id Subject Object Predicate Lexical cue
T100 127-137 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T101 73-86 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T102 141-153 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T103 355-371 http://purl.obolibrary.org/obo/GO_0038061 denotes NF-κB signalling
T104 566-582 http://purl.obolibrary.org/obo/GO_0038061 denotes NF-κB signalling
T105 361-371 http://purl.obolibrary.org/obo/GO_0023052 denotes signalling
T106 572-582 http://purl.obolibrary.org/obo/GO_0023052 denotes signalling
T107 621-633 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis

sentences

Id Subject Object Predicate Lexical cue
T2 69-303 Sentence denotes The transcription factor NF-κB plays crucial roles in the regulation of inflammation and mmune responses, and inappropriate NF-κB activity has been linked with many autoimmune and inflammatory diseases, including rheumatoid arthritis.
T3 304-477 Sentence denotes Cells employ a multilayered control system to keep NF-κB signalling in check, including a repertoire of negative feedback regulators ensuring termination of NF-κB responses.
T4 478-658 Sentence denotes Here we will review various negative regulatory mechanisms that have evolved to control NF-κB signalling and which have been implicated in the pathogenesis of rheumatoid arthritis.
T2 60-68 Sentence denotes Abstract
T3 69-303 Sentence denotes The transcription factor NF-κB plays crucial roles in the regulation of inflammation and mmune responses, and inappropriate NF-κB activity has been linked with many autoimmune and inflammatory diseases, including rheumatoid arthritis.
T4 304-477 Sentence denotes Cells employ a multilayered control system to keep NF-κB signalling in check, including a repertoire of negative feedback regulators ensuring termination of NF-κB responses.
T5 478-658 Sentence denotes Here we will review various negative regulatory mechanisms that have evolved to control NF-κB signalling and which have been implicated in the pathogenesis of rheumatoid arthritis.
T6 660-672 Sentence denotes Introduction

ICD10

Id Subject Object Predicate Lexical cue
T800 684-693 http://purl.bioontology.org/ontology/ICD10/M13.9 denotes arthritis
T799 673-693 http://purl.bioontology.org/ontology/ICD10/M06.9 denotes Rheumatoid arthritis
T109 282-302 http://purl.bioontology.org/ontology/ICD10/M06.9 denotes rheumatoid arthritis
T110 637-657 http://purl.bioontology.org/ontology/ICD10/M06.9 denotes rheumatoid arthritis
T112 293-302 http://purl.bioontology.org/ontology/ICD10/M13.9 denotes arthritis
T113 648-657 http://purl.bioontology.org/ontology/ICD10/M13.9 denotes arthritis
T108 38-58 http://purl.bioontology.org/ontology/ICD10/M06.9 denotes rheumatoid arthritis
T111 49-58 http://purl.bioontology.org/ontology/ICD10/M13.9 denotes arthritis

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T236 9-14 Protein denotes NF-κB
T1545 695-697 Protein denotes RA
T239 558-571 Regulation denotes control NF-κB
T238 179-223 Binding denotes inappropriate NF-κB activity has been linked
T237 193-198 Protein denotes NF-κB
T235 355-371 Protein denotes NF-κB signalling
T234 94-99 Protein denotes NF-κB
T233 304-309 Entity denotes Cells
T232 566-571 Protein denotes NF-κB
T231 461-466 Protein denotes NF-κB
R201 T232 T239 themeOf NF-κB,control NF-κB

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T214 23-34 Regulation denotes involvement
T215 73-99 Protein denotes transcription factor NF-κB
T216 193-198 Protein denotes NF-κB
T217 355-360 Protein denotes NF-κB
T218 461-466 Protein denotes NF-κB
T219 566-571 Protein denotes NF-κB
T220 558-565 Regulation denotes control
T211 9-14 Protein denotes NF-κB
R205 T219 T220 themeOf NF-κB,control