> top > docs > PMC:3218875 > spans > 13849-15166 > annotations

PMC:3218875 / 13849-15166 JSONTXT

Annnotations TAB JSON ListView MergeView

testone

Id Subject Object Predicate Lexical cue
T21324 891-902 Protein_catabolism denotes degradation
T21323 800-815 Phosphorylation denotes phosphorylation
T21322 780-788 Positive_regulation denotes mediates
T21321 739-753 Phosphorylation denotes phosphorylates
T21320 696-705 Positive_regulation denotes increased
T21319 404-413 Binding denotes recruited
T21318 330-341 Protein_catabolism denotes degradation
T21317 138-148 Gene_expression denotes expression
T21316 1294-1316 Protein denotes tumour necrosis factor
T21315 1289-1292 Protein denotes TNF
T21314 1222-1249 Protein denotes receptor activator of NF-κB
T21313 1216-1220 Protein denotes RANK
T21312 997-1002 Protein denotes TRAF1
T21311 990-995 Protein denotes TRAF3
T21310 950-954 Protein denotes RelB
T21309 914-917 Protein denotes p52
T21308 906-910 Protein denotes p100
T21307 795-799 Protein denotes p100
T21306 768-772 Protein denotes IKK1
T21305 730-733 Protein denotes NIK
T21304 706-709 Protein denotes NIK
T21303 664-667 Protein denotes NIK
T21302 642-647 Protein denotes TRAF3
T21301 624-627 Protein denotes NIK
T21300 605-610 Protein denotes TRAF3
T21299 558-559 Protein denotes 2
T21298 552-557 Protein denotes cIAP1
T21297 505-506 Protein denotes 2
T21296 499-504 Protein denotes cIAP1
T21295 437-442 Protein denotes TRAF2
T21294 395-400 Protein denotes TRAF3
T21293 358-361 Protein denotes NIK
T21292 345-348 Protein denotes NIK
T21291 259-260 Protein denotes 2
T21290 253-258 Protein denotes cIAP1
T21289 243-248 Protein denotes TRAF3
T21288 236-241 Protein denotes TRAF2
T21287 179-182 Protein denotes NIK
T21286 133-136 Protein denotes NIK
T21285 110-131 Protein denotes NF-κB inducing kinase
T21284 40-44 Protein denotes RANK
T21283 31-35 Protein denotes CD40
R13906 T21285 T21317 themeOf NF-κB inducing kinase,expression
R13907 T21286 T21285 equivalentTo NIK,NF-κB inducing kinase
R13908 T21292 T21318 themeOf NIK,degradation
R13909 T21294 T21319 themeOf TRAF3,recruited
R13910 T21304 T21320 themeOf NIK,increased
R13911 T21305 T21321 themeOf NIK,phosphorylates
R13912 T21306 T21321 themeOf IKK1,phosphorylates
R13913 T21306 T21322 causeOf IKK1,mediates
R13914 T21307 T21323 themeOf p100,phosphorylation
R13915 T21308 T21324 themeOf p100,degradation
R13916 T21309 T21324 themeOf p52,degradation
R13917 T21323 T21322 themeOf phosphorylation,mediates

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T22073 1316-1317 . denotes .
T22072 1310-1316 NN denotes factor
T22071 1301-1309 NN denotes necrosis
T22070 1294-1300 NN denotes tumour
T22069 1292-1293 , denotes ,
T22068 1289-1292 NNP denotes TNF
T22067 1287-1288 : denotes ;
T22066 1281-1287 NN denotes factor
T22065 1261-1280 VBD denotes receptor-associated
T22064 1257-1260 NNP denotes TNF
T22063 1255-1256 , denotes ,
T22062 1251-1255 NNP denotes TRAF
T22061 1249-1250 : denotes ;
T22060 1244-1249 NN denotes NF-κB
T22059 1241-1243 IN denotes of
T22058 1231-1240 NN denotes activator
T22057 1222-1230 NN denotes receptor
T22056 1220-1221 , denotes ,
T22055 1216-1220 NNP denotes RANK
T22054 1214-1215 : denotes ;
T22053 1208-1214 NN denotes factor
T22052 1200-1207 JJ denotes nuclear
T22051 1198-1199 , denotes ,
T22050 1196-1198 NNP denotes NF
T22049 1194-1195 : denotes ;
T22048 1188-1194 NN denotes kinase
T22047 1184-1187 NNP denotes IκB
T22046 1182-1183 , denotes ,
T22045 1179-1182 NNP denotes IKK
T22044 1177-1178 : denotes ;
T22043 1168-1177 NN denotes apoptosis
T22042 1165-1167 IN denotes of
T22041 1155-1164 NN denotes inhibitor
T22040 1146-1154 JJ denotes cellular
T22039 1144-1145 , denotes ,
T22038 1140-1144 NNP denotes cIAP
T22037 1138-1139 . denotes .
T22036 1131-1138 NNS denotes factors
T22035 1111-1130 JJ denotes receptor-associated
T22034 1107-1110 NNP denotes TNF
T22033 1101-1106 JJ denotes other
T22032 1096-1100 IN denotes with
T22031 1086-1095 VBG denotes competing
T22030 1083-1085 IN denotes by
T22029 1074-1082 RB denotes probably
T22028 1069-1073 JJS denotes most
T22027 1067-1068 , denotes ,
T22026 1060-1067 NN denotes pathway
T22025 1055-1059 DT denotes this
T22024 1052-1054 IN denotes of
T22023 1042-1051 NN denotes regulator
T22022 1033-1041 JJ denotes negative
T22021 1031-1032 DT denotes a
T22020 1028-1030 IN denotes as
T22019 1017-1027 VBN denotes identified
T22018 1012-1016 VBN denotes been
T22017 1007-1011 RB denotes also
T22016 1003-1006 VBZ denotes has
T22015 997-1002 CD denotes TRAF1
T22014 995-996 , denotes ,
T22013 990-995 CD denotes TRAF3
T22012 987-989 TO denotes to
T22011 982-986 JJ denotes Next
T22010 980-981 . denotes .
T22009 967-980 NN denotes transcription
T22008 958-966 VB denotes activate
T22007 955-957 TO denotes to
T22006 950-954 NNP denotes RelB
T22005 945-949 IN denotes with
T22004 933-944 NN denotes heterodimer
T22003 931-932 DT denotes a
T22002 925-930 VBZ denotes forms
T22001 919-924 WDT denotes which
T22000 917-918 , denotes ,
T21999 914-917 CD denotes p52
T21998 911-913 TO denotes to
T21997 906-910 CD denotes p100
T21996 903-905 IN denotes of
T21995 891-902 NN denotes degradation
T21994 879-890 JJ denotes proteasomal
T21993 871-878 JJ denotes partial
T21992 867-870 CC denotes and
T21991 848-866 NN denotes polyubiquitination
T21990 837-847 JJ denotes K48-linked
T21989 834-836 IN denotes by
T21988 825-833 VBN denotes followed
T21987 822-824 VBZ denotes is
T21986 817-821 DT denotes This
T21985 815-816 . denotes .
T21984 800-815 NN denotes phosphorylation
T21983 795-799 CD denotes p100
T21982 789-794 NNP denotes NF-κB
T21981 780-788 VBZ denotes mediates
T21980 774-779 WDT denotes which
T21979 772-773 , denotes ,
T21978 768-772 NNP denotes IKK1
T21977 758-767 VBZ denotes activates
T21976 754-757 CC denotes and
T21975 739-753 VBZ denotes phosphorylates
T21974 734-738 RB denotes then
T21973 730-733 NNP denotes NIK
T21972 728-729 . denotes .
T21971 724-728 NN denotes cell
T21970 720-723 DT denotes the
T21969 717-719 IN denotes in
T21968 710-716 NNS denotes levels
T21967 706-709 NNP denotes NIK
T21966 696-705 VBN denotes increased
T21965 693-695 IN denotes in
T21964 683-692 VBG denotes resulting
T21963 681-682 , denotes ,
T21962 671-681 VBN denotes stabilised
T21961 668-670 VBZ denotes is
T21960 664-667 NNP denotes NIK
T21959 660-663 CC denotes and
T21958 651-659 JJ denotes degraded
T21957 648-650 VBZ denotes is
T21956 642-647 CD denotes TRAF3
T21955 640-641 , denotes ,
T21954 634-640 NN denotes result
T21953 632-633 DT denotes a
T21952 629-631 IN denotes As
T21951 627-628 . denotes .
T21950 624-627 NNP denotes NIK
T21949 619-623 IN denotes than
T21948 612-618 RB denotes rather
T21902 295-313 NN denotes polyubiquitination
T21901 284-294 JJ denotes K48-linked
T21900 280-283 DT denotes the
T21899 268-279 VBZ denotes facilitates
T21898 262-267 WDT denotes which
T21897 260-261 , denotes ,
T21896 253-260 NNP denotes cIAP1/2
T21895 249-252 CC denotes and
T21894 243-248 CD denotes TRAF3
T21893 241-242 , denotes ,
T21892 236-241 CD denotes TRAF2
T21891 228-235 VBZ denotes ligases
T21890 218-227 NN denotes ubiquitin
T21889 214-217 DT denotes the
T21888 209-213 IN denotes with
T21887 201-208 NN denotes complex
T21886 191-200 JJ denotes cytosolic
T21885 189-190 DT denotes a
T21884 183-188 VBZ denotes forms
T21883 179-182 NNP denotes NIK
T21882 173-178 NNS denotes cells
T21881 160-172 JJ denotes unstimulated
T21880 157-159 IN denotes In
T21879 155-156 . denotes .
T21878 149-155 NNS denotes levels
T21877 138-148 NN denotes expression
T21876 136-137 -RRB- denotes )
T21875 133-136 NNP denotes NIK
T21874 132-133 -LRB- denotes (
T21873 125-131 NN denotes kinase
T21872 116-124 VBG denotes inducing
T21871 110-115 JJ denotes NF-κB
T21870 107-109 IN denotes on
T21869 97-106 JJ denotes dependent
T21868 94-96 VBZ denotes is
T21867 89-93 WDT denotes that
T21866 81-88 NN denotes pathway
T21865 75-80 NN denotes NF-κB
T21864 62-74 JJ denotes noncanonical
T21863 58-61 DT denotes the
T21862 49-57 VB denotes activate
T21861 45-48 MD denotes can
T21860 40-44 NNP denotes RANK
T21859 36-39 CC denotes and
T21858 31-35 CD denotes CD40
T21857 29-30 . denotes .
T21856 19-29 VBG denotes signalling
T21855 13-18 NNP denotes NF-κB
T21854 0-12 NNP denotes Noncanonical
T21924 429-430 , denotes ,
T21923 421-429 NN denotes receptor
T21922 417-420 DT denotes the
T21921 414-416 TO denotes to
T21920 404-413 VBN denotes recruited
T21919 401-403 VBZ denotes is
T21918 395-400 CD denotes TRAF3
T21917 393-394 , denotes ,
T21916 386-393 JJ denotes binding
T21915 379-385 JJ denotes ligand
T21914 374-378 IN denotes Upon
T21913 372-373 . denotes .
T21912 369-372 JJ denotes low
T21911 362-368 NNS denotes levels
T21910 358-361 NNP denotes NIK
T21909 350-357 VBG denotes keeping
T21908 348-349 , denotes ,
T21907 345-348 NNP denotes NIK
T21906 342-344 IN denotes of
T21905 330-341 NN denotes degradation
T21904 318-329 JJ denotes proteasomal
T21903 314-317 CC denotes and
T21947 610-611 , denotes ,
T21946 605-610 CD denotes TRAF3
T21945 602-604 TO denotes to
T21944 583-601 NN denotes polyubiquitination
T21943 572-582 JJ denotes K48-linked
T21942 568-571 PRP$ denotes its
T21941 560-567 VBZ denotes directs
T21940 552-559 JJ denotes cIAP1/2
T21939 539-551 RB denotes Subsequently
T21938 537-538 . denotes .
T21937 527-537 NN denotes activation
T21936 521-526 PRP$ denotes their
T21935 518-520 IN denotes in
T21934 508-517 VBG denotes resulting
T21933 506-507 , denotes ,
T21932 499-506 NNP denotes cIAP1/2
T21931 496-498 IN denotes of
T21930 477-495 NN denotes polyubiquitination
T21929 466-476 JJ denotes K63-linked
T21928 451-465 JJ denotes nondegradative
T21927 443-450 VBZ denotes directs
T21926 437-442 CD denotes TRAF2
T21925 431-436 WRB denotes where
R14226 T21854 T21855 compound Noncanonical,NF-κB
R14227 T21855 T21855 ROOT NF-κB,NF-κB
R14228 T21856 T21855 acl signalling,NF-κB
R14229 T21857 T21856 punct .,signalling
R14230 T21858 T21858 ROOT CD40,CD40
R14231 T21859 T21858 cc and,CD40
R14232 T21860 T21862 nsubj RANK,activate
R14233 T21861 T21862 aux can,activate
R14234 T21862 T21858 conj activate,CD40
R14235 T21863 T21866 det the,pathway
R14236 T21864 T21866 amod noncanonical,pathway
R14237 T21865 T21866 compound NF-κB,pathway
R14238 T21866 T21862 dobj pathway,activate
R14239 T21867 T21868 nsubj that,is
R14240 T21868 T21866 relcl is,pathway
R14241 T21869 T21868 acomp dependent,is
R14242 T21870 T21869 prep on,dependent
R14243 T21871 T21872 nsubj NF-κB,inducing
R14244 T21872 T21870 pcomp inducing,on
R14245 T21873 T21878 nmod kinase,levels
R14246 T21874 T21878 punct (,levels
R14247 T21875 T21878 compound NIK,levels
R14248 T21876 T21877 punct ),expression
R14249 T21877 T21878 compound expression,levels
R14250 T21878 T21872 dobj levels,inducing
R14251 T21879 T21862 punct .,activate
R14252 T21880 T21884 prep In,forms
R14253 T21881 T21882 amod unstimulated,cells
R14254 T21882 T21880 pobj cells,In
R14255 T21883 T21884 nsubj NIK,forms
R14256 T21884 T21884 ROOT forms,forms
R14257 T21885 T21887 det a,complex
R14258 T21886 T21887 amod cytosolic,complex
R14259 T21887 T21884 dobj complex,forms
R14260 T21888 T21887 prep with,complex
R14261 T21889 T21890 det the,ubiquitin
R14262 T21890 T21891 nsubj ubiquitin,ligases
R14263 T21891 T21884 conj ligases,forms
R14264 T21892 T21891 dobj TRAF2,ligases
R14265 T21893 T21892 punct ",",TRAF2
R14266 T21894 T21892 conj TRAF3,TRAF2
R14267 T21895 T21894 cc and,TRAF3
R14268 T21896 T21894 conj cIAP1/2,TRAF3
R14269 T21897 T21896 punct ",",cIAP1/2
R14270 T21898 T21899 nsubj which,facilitates
R14271 T21899 T21896 relcl facilitates,cIAP1/2
R14272 T21900 T21902 det the,polyubiquitination
R14273 T21901 T21902 amod K48-linked,polyubiquitination
R14274 T21902 T21899 dobj polyubiquitination,facilitates
R14275 T21903 T21902 cc and,polyubiquitination
R14276 T21904 T21905 amod proteasomal,degradation
R14277 T21905 T21902 conj degradation,polyubiquitination
R14278 T21906 T21905 prep of,degradation
R14279 T21907 T21906 pobj NIK,of
R14280 T21908 T21891 punct ",",ligases
R14281 T21909 T21891 advcl keeping,ligases
R14282 T21910 T21911 compound NIK,levels
R14283 T21911 T21909 dobj levels,keeping
R14284 T21912 T21909 oprd low,keeping
R14285 T21913 T21891 punct .,ligases
R14286 T21914 T21916 mark Upon,binding
R14287 T21915 T21916 advmod ligand,binding
R14288 T21916 T21920 advcl binding,recruited
R14289 T21917 T21920 punct ",",recruited
R14290 T21918 T21920 nsubjpass TRAF3,recruited
R14291 T21919 T21920 auxpass is,recruited
R14292 T21920 T21920 ROOT recruited,recruited
R14293 T21921 T21920 prep to,recruited
R14294 T21922 T21923 det the,receptor
R14295 T21923 T21921 pobj receptor,to
R14296 T21924 T21923 punct ",",receptor
R14297 T21925 T21927 advmod where,directs
R14298 T21926 T21927 nummod TRAF2,directs
R14299 T21927 T21923 relcl directs,receptor
R14300 T21928 T21930 amod nondegradative,polyubiquitination
R14301 T21929 T21930 amod K63-linked,polyubiquitination
R14302 T21930 T21927 dobj polyubiquitination,directs
R14303 T21931 T21930 prep of,polyubiquitination
R14304 T21932 T21931 pobj cIAP1/2,of
R14305 T21933 T21927 punct ",",directs
R14306 T21934 T21920 advcl resulting,recruited
R14307 T21935 T21934 prep in,resulting
R14308 T21936 T21937 poss their,activation
R14309 T21937 T21935 pobj activation,in
R14310 T21938 T21920 punct .,recruited
R14311 T21939 T21941 advmod Subsequently,directs
R14312 T21940 T21941 nsubj cIAP1/2,directs
R14313 T21941 T21941 ROOT directs,directs
R14314 T21942 T21944 poss its,polyubiquitination
R14315 T21943 T21944 amod K48-linked,polyubiquitination
R14316 T21944 T21941 dobj polyubiquitination,directs
R14317 T21945 T21944 prep to,polyubiquitination
R14318 T21946 T21945 pobj TRAF3,to
R14319 T21947 T21944 punct ",",polyubiquitination
R14320 T21948 T21949 advmod rather,than
R14321 T21949 T21944 cc than,polyubiquitination
R14322 T21950 T21949 pobj NIK,than
R14323 T21951 T21941 punct .,directs
R14324 T21952 T21957 prep As,is
R14325 T21953 T21954 det a,result
R14326 T21954 T21952 pobj result,As
R14327 T21955 T21957 punct ",",is
R14328 T21956 T21957 nsubj TRAF3,is
R14329 T21957 T21957 ROOT is,is
R14330 T21958 T21957 acomp degraded,is
R14331 T21959 T21957 cc and,is
R14332 T21960 T21961 nsubj NIK,is
R14333 T21961 T21957 conj is,is
R14334 T21962 T21961 acomp stabilised,is
R14335 T21963 T21961 punct ",",is
R14336 T21964 T21961 advcl resulting,is
R14337 T21965 T21964 prep in,resulting
R14338 T21966 T21968 amod increased,levels
R14339 T21967 T21968 compound NIK,levels
R14340 T21968 T21965 pobj levels,in
R14341 T21969 T21968 prep in,levels
R14342 T21970 T21971 det the,cell
R14343 T21971 T21969 pobj cell,in
R14344 T21972 T21961 punct .,is
R14345 T21973 T21975 nsubj NIK,phosphorylates
R14346 T21974 T21975 advmod then,phosphorylates
R14347 T21975 T21975 ROOT phosphorylates,phosphorylates
R14348 T21976 T21975 cc and,phosphorylates
R14349 T21977 T21975 conj activates,phosphorylates
R14350 T21978 T21977 dobj IKK1,activates
R14351 T21979 T21978 punct ",",IKK1
R14352 T21980 T21981 nsubj which,mediates
R14353 T21981 T21978 relcl mediates,IKK1
R14354 T21982 T21984 nmod NF-κB,phosphorylation
R14355 T21983 T21984 nummod p100,phosphorylation
R14356 T21984 T21981 dobj phosphorylation,mediates
R14357 T21985 T21975 punct .,phosphorylates
R14358 T21986 T21988 nsubjpass This,followed
R14359 T21987 T21988 auxpass is,followed
R14360 T21988 T21988 ROOT followed,followed
R14361 T21989 T21988 agent by,followed
R14362 T21990 T21991 amod K48-linked,polyubiquitination
R14363 T21991 T21989 pobj polyubiquitination,by
R14364 T21992 T21991 cc and,polyubiquitination
R14365 T21993 T21995 amod partial,degradation
R14366 T21994 T21995 amod proteasomal,degradation
R14367 T21995 T21991 conj degradation,polyubiquitination
R14368 T21996 T21995 prep of,degradation
R14369 T21997 T21996 pobj p100,of
R14370 T21998 T21995 prep to,degradation
R14371 T21999 T21998 pobj p52,to
R14372 T22000 T21999 punct ",",p52
R14373 T22001 T22002 nsubj which,forms
R14374 T22002 T21999 relcl forms,p52
R14375 T22003 T22004 det a,heterodimer
R14376 T22004 T22002 dobj heterodimer,forms
R14377 T22005 T22004 prep with,heterodimer
R14378 T22006 T22005 pobj RelB,with
R14379 T22007 T22008 aux to,activate
R14380 T22008 T22002 advcl activate,forms
R14381 T22009 T22008 dobj transcription,activate
R14382 T22010 T21988 punct .,followed
R14383 T22011 T22019 advmod Next,identified
R14384 T22012 T22011 prep to,Next
R14385 T22013 T22012 pobj TRAF3,to
R14386 T22014 T22019 punct ",",identified
R14387 T22015 T22019 nsubjpass TRAF1,identified
R14388 T22016 T22019 aux has,identified
R14389 T22017 T22019 advmod also,identified
R14390 T22018 T22019 auxpass been,identified
R14391 T22019 T22019 ROOT identified,identified
R14392 T22020 T22019 prep as,identified
R14393 T22021 T22023 det a,regulator
R14394 T22022 T22023 amod negative,regulator
R14395 T22023 T22020 pobj regulator,as
R14396 T22024 T22023 prep of,regulator
R14397 T22025 T22026 det this,pathway
R14398 T22026 T22024 pobj pathway,of
R14399 T22027 T22023 punct ",",regulator
R14400 T22028 T22029 advmod most,probably
R14401 T22029 T22030 advmod probably,by
R14402 T22030 T22019 agent by,identified
R14403 T22031 T22030 pcomp competing,by
R14404 T22032 T22031 prep with,competing
R14405 T22033 T22036 amod other,factors
R14406 T22034 T22036 nmod TNF,factors
R14407 T22035 T22036 amod receptor-associated,factors
R14408 T22036 T22032 pobj factors,with
R14409 T22037 T22019 punct .,identified
R14410 T22038 T22038 ROOT cIAP,cIAP
R14411 T22039 T22038 punct ",",cIAP
R14412 T22040 T22041 amod cellular,inhibitor
R14413 T22041 T22038 appos inhibitor,cIAP
R14414 T22042 T22041 prep of,inhibitor
R14415 T22043 T22042 pobj apoptosis,of
R14416 T22044 T22038 punct ;,cIAP
R14417 T22045 T22038 conj IKK,cIAP
R14418 T22046 T22045 punct ",",IKK
R14419 T22047 T22048 compound IκB,kinase
R14420 T22048 T22045 appos kinase,IKK
R14421 T22049 T22045 punct ;,IKK
R14422 T22050 T22045 conj NF,IKK
R14423 T22051 T22050 punct ",",NF
R14424 T22052 T22053 amod nuclear,factor
R14425 T22053 T22050 appos factor,NF
R14426 T22054 T22050 punct ;,NF
R14427 T22055 T22050 conj RANK,NF
R14428 T22056 T22055 punct ",",RANK
R14429 T22057 T22058 compound receptor,activator
R14430 T22058 T22038 appos activator,cIAP
R14431 T22059 T22058 prep of,activator
R14432 T22060 T22059 pobj NF-κB,of
R14433 T22061 T22038 punct ;,cIAP
R14434 T22062 T22038 conj TRAF,cIAP
R14435 T22063 T22066 punct ",",factor
R14436 T22064 T22066 nmod TNF,factor
R14437 T22065 T22066 amod receptor-associated,factor
R14438 T22066 T22038 appos factor,cIAP
R14439 T22067 T22038 punct ;,cIAP
R14440 T22068 T22038 conj TNF,cIAP
R14441 T22069 T22068 punct ",",TNF
R14442 T22070 T22072 compound tumour,factor
R14443 T22071 T22072 compound necrosis,factor
R14444 T22072 T22038 appos factor,cIAP
R14445 T22073 T22038 punct .,cIAP

DLUT931

Id Subject Object Predicate Lexical cue
T22211 1155-1164 Negative_regulation denotes inhibitor
T22210 1042-1051 Regulation denotes regulator
T22209 933-944 Binding denotes heterodimer
T22208 891-902 Protein_catabolism denotes degradation
T22207 800-815 Phosphorylation denotes phosphorylation
T22206 780-788 Positive_regulation denotes mediates
T22205 758-767 Positive_regulation denotes activates
T22204 696-705 Positive_regulation denotes increased
T22203 683-692 Positive_regulation denotes resulting
T22202 671-681 Positive_regulation denotes stabilised
T22201 651-659 Protein_catabolism denotes degraded
T22200 583-601 Binding denotes polyubiquitination
T22199 443-450 Negative_regulation denotes directs
T22198 477-495 Positive_regulation denotes polyubiquitination
T22197 451-465 Protein_catabolism denotes nondegradative
T22196 404-413 Binding denotes recruited
T22195 268-279 Positive_regulation denotes facilitates
T22194 369-372 Positive_regulation denotes low
T22193 330-341 Protein_catabolism denotes degradation
T22192 295-313 Binding denotes polyubiquitination
T22191 97-106 Regulation denotes dependent
T22190 138-148 Gene_expression denotes expression
T22189 1294-1316 Protein denotes tumour necrosis factor
T22188 1289-1292 Protein denotes TNF
T22187 1222-1249 Protein denotes receptor activator of NF-κB
T22186 1216-1220 Protein denotes RANK
T22185 997-1002 Protein denotes TRAF1
T22184 990-995 Protein denotes TRAF3
T22183 950-954 Protein denotes RelB
T22182 914-917 Protein denotes p52
T22181 906-910 Protein denotes p100
T22180 795-799 Protein denotes p100
T22179 768-772 Protein denotes IKK1
T22178 730-733 Protein denotes NIK
T22177 706-709 Protein denotes NIK
T22176 664-667 Protein denotes NIK
T22175 642-647 Protein denotes TRAF3
T22174 624-627 Protein denotes NIK
T22173 605-610 Protein denotes TRAF3
T22172 558-559 Protein denotes 2
T22171 552-557 Protein denotes cIAP1
T22170 505-506 Protein denotes 2
T22169 499-504 Protein denotes cIAP1
T22168 437-442 Protein denotes TRAF2
T22167 395-400 Protein denotes TRAF3
T22166 259-260 Protein denotes 2
T22165 253-258 Protein denotes cIAP1
T22164 243-248 Protein denotes TRAF3
T22163 236-241 Protein denotes TRAF2
T22162 179-182 Protein denotes NIK
T22161 358-361 Protein denotes NIK
T22160 345-348 Protein denotes NIK
T22159 133-136 Protein denotes NIK
T22158 110-131 Protein denotes NF-κB inducing kinase
T22157 40-44 Protein denotes RANK
T22156 31-35 Protein denotes CD40
R14470 T22158 T22190 themeOf NF-κB inducing kinase,expression
R14471 T22159 T22190 themeOf NIK,expression
R14472 T22160 T22192 themeOf NIK,polyubiquitination
R14473 T22160 T22193 themeOf NIK,degradation
R14474 T22161 T22194 themeOf NIK,low
R14475 T22167 T22196 themeOf TRAF3,recruited
R14476 T22168 T22199 causeOf TRAF2,directs
R14477 T22168 T22199 causeOf TRAF2,directs
R14478 T22168 T22199 causeOf TRAF2,directs
R14479 T22168 T22199 causeOf TRAF2,directs
R14480 T22169 T22197 themeOf cIAP1,nondegradative
R14481 T22169 T22198 themeOf cIAP1,polyubiquitination
R14482 T22170 T22197 themeOf 2,nondegradative
R14483 T22170 T22198 themeOf 2,polyubiquitination
R14484 T22171 T22200 themeOf cIAP1,polyubiquitination
R14485 T22173 T22200 themeOf TRAF3,polyubiquitination
R14486 T22175 T22201 themeOf TRAF3,degraded
R14487 T22176 T22202 themeOf NIK,stabilised
R14488 T22177 T22203 themeOf NIK,resulting
R14489 T22177 T22204 themeOf NIK,increased
R14490 T22178 T22205 causeOf NIK,activates
R14491 T22179 T22205 themeOf IKK1,activates
R14492 T22179 T22206 themeOf IKK1,mediates
R14493 T22180 T22207 themeOf p100,phosphorylation
R14494 T22181 T22208 themeOf p100,degradation
R14495 T22182 T22208 themeOf p52,degradation
R14496 T22183 T22209 themeOf RelB,heterodimer
R14497 T22185 T22210 themeOf TRAF1,regulator
R14498 T22186 T22211 themeOf RANK,inhibitor
R14499 T22187 T22211 themeOf receptor activator of NF-κB,inhibitor
R14500 T22188 T22211 themeOf TNF,inhibitor
R14501 T22189 T22211 themeOf tumour necrosis factor,inhibitor
R14502 T22190 T22191 themeOf expression,dependent
R14503 T22190 T22191 themeOf expression,dependent
R14504 T22192 T22195 themeOf polyubiquitination,facilitates
R14505 T22193 T22195 themeOf degradation,facilitates
R14506 T22197 T22198 themeOf nondegradative,polyubiquitination
R14507 T22197 T22198 themeOf nondegradative,polyubiquitination
R14508 T22198 T22199 themeOf polyubiquitination,directs
R14509 T22198 T22199 themeOf polyubiquitination,directs
R14510 T22198 T22199 themeOf polyubiquitination,directs
R14511 T22198 T22199 themeOf polyubiquitination,directs
R14512 T22204 T22203 themeOf increased,resulting
R14513 T22207 T22206 themeOf phosphorylation,mediates

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T22106 1257-1287 http://www.uniprot.org/uniprot/Q9Y4K3 denotes TNF receptor-associated factor
T22105 1289-1292 http://www.uniprot.org/uniprot/P01375 denotes TNF
T22104 1257-1260 http://www.uniprot.org/uniprot/P01375 denotes TNF
T22103 1107-1110 http://www.uniprot.org/uniprot/P01375 denotes TNF
T22102 950-954 http://www.uniprot.org/uniprot/Q01201 denotes RelB
T22101 914-917 http://www.uniprot.org/uniprot/Q00653 denotes p52
T22100 906-910 http://www.uniprot.org/uniprot/Q00653 denotes p100
T22099 795-799 http://www.uniprot.org/uniprot/Q00653 denotes p100
T22098 1184-1194 http://www.uniprot.org/uniprot/Q60680-2 denotes IκB kinase
T22097 768-772 http://www.uniprot.org/uniprot/Q60680-2 denotes IKK1
T22096 1184-1194 http://www.uniprot.org/uniprot/O15111 denotes IκB kinase
T22095 768-772 http://www.uniprot.org/uniprot/O15111 denotes IKK1
T22094 552-557 http://www.uniprot.org/uniprot/Q13490 denotes cIAP1
T22093 499-504 http://www.uniprot.org/uniprot/Q13490 denotes cIAP1
T22092 253-258 http://www.uniprot.org/uniprot/Q13490 denotes cIAP1
T22091 1257-1287 http://www.uniprot.org/uniprot/Q13114 denotes TNF receptor-associated factor
T22090 990-995 http://www.uniprot.org/uniprot/Q13114 denotes TRAF3
T22089 642-647 http://www.uniprot.org/uniprot/Q13114 denotes TRAF3
T22088 605-610 http://www.uniprot.org/uniprot/Q13114 denotes TRAF3
T22087 395-400 http://www.uniprot.org/uniprot/Q13114 denotes TRAF3
T22086 243-248 http://www.uniprot.org/uniprot/Q13114 denotes TRAF3
T22085 1257-1287 http://www.uniprot.org/uniprot/Q12933 denotes TNF receptor-associated factor
T22084 437-442 http://www.uniprot.org/uniprot/Q12933 denotes TRAF2
T22083 236-241 http://www.uniprot.org/uniprot/Q12933 denotes TRAF2
T22082 730-733 http://www.uniprot.org/uniprot/Q99558 denotes NIK
T22081 706-709 http://www.uniprot.org/uniprot/Q99558 denotes NIK
T22080 664-667 http://www.uniprot.org/uniprot/Q99558 denotes NIK
T22079 624-627 http://www.uniprot.org/uniprot/Q99558 denotes NIK
T22078 358-361 http://www.uniprot.org/uniprot/Q99558 denotes NIK
T22077 345-348 http://www.uniprot.org/uniprot/Q99558 denotes NIK
T22076 179-182 http://www.uniprot.org/uniprot/Q99558 denotes NIK
T22075 133-136 http://www.uniprot.org/uniprot/Q99558 denotes NIK
T22074 31-35 http://www.uniprot.org/uniprot/P25942 denotes CD40

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T21531 1294-1316 Protein denotes tumour necrosis factor
T21530 1289-1292 Protein denotes TNF
T21529 1222-1249 Protein denotes receptor activator of NF-κB
T21528 1216-1220 Protein denotes RANK
T21527 997-1002 Protein denotes TRAF1
T21526 990-995 Protein denotes TRAF3
T21525 950-954 Protein denotes RelB
T21524 914-917 Protein denotes p52
T21523 906-910 Protein denotes p100
T21522 795-799 Protein denotes p100
T21521 768-772 Protein denotes IKK1
T21520 730-733 Protein denotes NIK
T21519 706-709 Protein denotes NIK
T21518 664-667 Protein denotes NIK
T21517 642-647 Protein denotes TRAF3
T21516 624-627 Protein denotes NIK
T21515 605-610 Protein denotes TRAF3
T21514 558-559 Protein denotes 2
T21513 552-557 Protein denotes cIAP1
T21512 505-506 Protein denotes 2
T21511 499-504 Protein denotes cIAP1
T21510 437-442 Protein denotes TRAF2
T21509 395-400 Protein denotes TRAF3
T21508 358-361 Protein denotes NIK
T21507 345-348 Protein denotes NIK
T21506 259-260 Protein denotes 2
T21505 253-258 Protein denotes cIAP1
T21504 243-248 Protein denotes TRAF3
T21503 236-241 Protein denotes TRAF2
T21502 179-182 Protein denotes NIK
T21501 133-136 Protein denotes NIK
T21500 110-131 Protein denotes NF-κB inducing kinase
T21499 40-44 Protein denotes RANK
T21498 31-35 Protein denotes CD40

bionlp-st-ge-2016-coref

Id Subject Object Predicate Lexical cue
T21497 800-815 Antecedent denotes phosphorylation
T21496 817-821 Anaphor denotes This
T21495 768-772 Antecedent denotes IKK1
T21494 774-779 Anaphor denotes which
T21493 505-506 Antecedent denotes 2
T21492 499-504 Antecedent denotes cIAP1
T21491 521-526 Anaphor denotes their
T21490 243-248 Antecedent denotes TRAF3
T21489 236-241 Antecedent denotes TRAF2
T21488 262-267 Anaphor denotes which
R14003 T21488 T21489 boundBy which,TRAF2
R14004 T21488 T21490 boundBy which,TRAF3
R14005 T21491 T21492 boundBy their,cIAP1
R14006 T21491 T21493 boundBy their,2
R14007 T21494 T21495 boundBy which,IKK1
R14008 T21496 T21497 boundBy This,phosphorylation

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T21741 1310-1316 NN denotes factor
T21740 1301-1309 NN denotes necrosis
T21739 1294-1300 NN denotes tumour
T21738 1292-1293 -COMMA- denotes ,
T21737 1289-1292 NN denotes TNF
T21736 1287-1288 -COLON- denotes ;
T21735 1281-1287 NN denotes factor
T21734 1261-1280 JJ denotes receptor-associated
T21733 1257-1260 NN denotes TNF
T21732 1255-1256 -COMMA- denotes ,
T21731 1251-1255 NN denotes TRAF
T21730 1249-1250 -COLON- denotes ;
T21729 1244-1249 NN denotes NF-κB
T21728 1241-1243 IN denotes of
T21727 1231-1240 NN denotes activator
T21726 1222-1230 NN denotes receptor
T21725 1220-1221 -COMMA- denotes ,
T21724 1216-1220 NN denotes RANK
T21723 1214-1215 -COLON- denotes ;
T21722 1208-1214 NN denotes factor
T21721 1200-1207 JJ denotes nuclear
T21720 1198-1199 -COMMA- denotes ,
T21719 1196-1198 NN denotes NF
T21718 1194-1195 -COLON- denotes ;
T21717 1188-1194 NN denotes kinase
T21716 1184-1187 NN denotes IκB
T21715 1182-1183 -COMMA- denotes ,
T21714 1179-1182 NN denotes IKK
T21713 1177-1178 -COLON- denotes ;
T21712 1168-1177 NN denotes apoptosis
T21711 1165-1167 IN denotes of
T21710 1155-1164 NN denotes inhibitor
T21709 1146-1154 JJ denotes cellular
T21708 1144-1145 -COMMA- denotes ,
T21707 1140-1144 NN denotes cIAP
T21706 1131-1139 NN denotes factors.
T21705 1111-1130 JJ denotes receptor-associated
T21704 1107-1110 NN denotes TNF
T21703 1101-1106 JJ denotes other
T21702 1096-1100 IN denotes with
T21701 1086-1095 VB denotes competing
T21700 1083-1085 IN denotes by
T21699 1074-1082 RB denotes probably
T21698 1069-1073 RB denotes most
T21697 1067-1068 -COMMA- denotes ,
T21696 1060-1067 NN denotes pathway
T21695 1055-1059 DT denotes this
T21694 1052-1054 IN denotes of
T21693 1042-1051 NN denotes regulator
T21692 1033-1041 JJ denotes negative
T21691 1031-1032 DT denotes a
T21690 1028-1030 IN denotes as
T21689 1017-1027 VB denotes identified
T21688 1012-1016 VB denotes been
T21687 1007-1011 RB denotes also
T21686 1003-1006 VB denotes has
T21685 997-1002 NN denotes TRAF1
T21684 995-996 -COMMA- denotes ,
T21683 990-995 NN denotes TRAF3
T21682 987-989 TO denotes to
T21681 982-986 JJ denotes Next
T21680 967-980 NN denotes transcription
T21679 958-966 VB denotes activate
T21678 955-957 TO denotes to
T21677 950-954 NN denotes RelB
T21676 945-949 IN denotes with
T21675 933-944 NN denotes heterodimer
T21674 931-932 DT denotes a
T21673 925-930 VB denotes forms
T21672 919-924 WDT denotes which
T21671 917-918 -COMMA- denotes ,
T21670 914-917 NN denotes p52
T21669 911-913 TO denotes to
T21668 906-910 NN denotes p100
T21667 903-905 IN denotes of
T21666 891-902 NN denotes degradation
T21665 879-890 JJ denotes proteasomal
T21664 871-878 JJ denotes partial
T21663 867-870 CC denotes and
T21662 848-866 NN denotes polyubiquitination
T21661 837-847 JJ denotes K48-linked
T21660 834-836 IN denotes by
T21659 825-833 VB denotes followed
T21658 822-824 VB denotes is
T21657 817-821 DT denotes This
T21656 800-815 NN denotes phosphorylation
T21655 795-799 NN denotes p100
T21654 789-794 NN denotes NF-κB
T21653 780-788 VB denotes mediates
T21652 774-779 WDT denotes which
T21651 772-773 -COMMA- denotes ,
T21650 768-772 NN denotes IKK1
T21649 758-767 VB denotes activates
T21648 754-757 CC denotes and
T21647 739-753 VB denotes phosphorylates
T21646 734-738 RB denotes then
T21645 730-733 NN denotes NIK
T21644 724-728 NN denotes cell
T21643 720-723 DT denotes the
T21642 717-719 IN denotes in
T21641 710-716 NN denotes levels
T21640 706-709 NN denotes NIK
T21639 696-705 VB denotes increased
T21638 693-695 IN denotes in
T21637 683-692 VB denotes resulting
T21636 681-682 -COMMA- denotes ,
T21635 671-681 VB denotes stabilised
T21634 668-670 VB denotes is
T21633 664-667 NN denotes NIK
T21632 660-663 CC denotes and
T21631 651-659 VB denotes degraded
T21630 648-650 VB denotes is
T21629 642-647 NN denotes TRAF3
T21628 640-641 -COMMA- denotes ,
T21627 634-640 NN denotes result
T21626 632-633 DT denotes a
T21625 629-631 IN denotes As
T21624 624-627 NN denotes NIK
T21623 619-623 IN denotes than
T21622 612-618 RB denotes rather
T21621 610-611 -COMMA- denotes ,
T21620 605-610 NN denotes TRAF3
T21619 602-604 TO denotes to
T21618 583-601 NN denotes polyubiquitination
T21617 572-582 JJ denotes K48-linked
T21616 568-571 PRP-DOLLAR- denotes its
T21615 560-567 VB denotes directs
T21614 552-559 NN denotes cIAP1/2
T21613 539-551 RB denotes Subsequently
T21612 527-537 NN denotes activation
T21611 521-526 PRP-DOLLAR- denotes their
T21610 518-520 IN denotes in
T21594 401-403 VB denotes is
T21593 395-400 NN denotes TRAF3
T21592 393-394 -COMMA- denotes ,
T21591 386-393 NN denotes binding
T21590 379-385 NN denotes ligand
T21589 374-378 IN denotes Upon
T21588 369-372 JJ denotes low
T21587 362-368 NN denotes levels
T21586 358-361 NN denotes NIK
T21585 350-357 VB denotes keeping
T21584 348-349 -COMMA- denotes ,
T21583 345-348 NN denotes NIK
T21582 342-344 IN denotes of
T21581 330-341 NN denotes degradation
T21580 318-329 JJ denotes proteasomal
T21579 314-317 CC denotes and
T21578 295-313 NN denotes polyubiquitination
T21577 284-294 JJ denotes K48-linked
T21576 280-283 DT denotes the
T21575 268-279 VB denotes facilitates
T21574 262-267 WDT denotes which
T21573 260-261 -COMMA- denotes ,
T21572 253-260 NN denotes cIAP1/2
T21571 249-252 CC denotes and
T21570 243-248 NN denotes TRAF3
T21569 241-242 -COMMA- denotes ,
T21568 236-241 NN denotes TRAF2
T21567 228-235 NN denotes ligases
T21566 218-227 NN denotes ubiquitin
T21565 214-217 DT denotes the
T21564 209-213 IN denotes with
T21563 201-208 NN denotes complex
T21562 191-200 JJ denotes cytosolic
T21561 189-190 DT denotes a
T21560 183-188 VB denotes forms
T21559 179-182 NN denotes NIK
T21558 173-178 NN denotes cells
T21557 160-172 JJ denotes unstimulated
T21556 157-159 IN denotes In
T21555 149-155 NN denotes levels
T21554 138-148 NN denotes expression
T21553 136-137 -RRB- denotes )
T21552 133-136 NN denotes NIK
T21551 132-133 -LRB- denotes (
T21550 125-131 NN denotes kinase
T21549 116-124 VB denotes inducing
T21548 110-115 NN denotes NF-κB
T21547 107-109 IN denotes on
T21546 97-106 JJ denotes dependent
T21545 94-96 VB denotes is
T21544 89-93 WDT denotes that
T21543 81-88 NN denotes pathway
T21542 75-80 NN denotes NF-κB
T21541 62-74 JJ denotes noncanonical
T21540 58-61 DT denotes the
T21539 49-57 VB denotes activate
T21538 45-48 MD denotes can
T21537 40-44 NN denotes RANK
T21536 36-39 CC denotes and
T21535 31-35 NN denotes CD40
T21534 19-29 NN denotes signalling
T21533 13-18 NN denotes NF-κB
T21532 0-12 JJ denotes Noncanonical
T21605 477-495 NN denotes polyubiquitination
T21604 466-476 JJ denotes K63-linked
T21603 451-465 JJ denotes nondegradative
T21602 443-450 VB denotes directs
T21601 437-442 NN denotes TRAF2
T21600 431-436 WRB denotes where
T21599 429-430 -COMMA- denotes ,
T21598 421-429 NN denotes receptor
T21597 417-420 DT denotes the
T21596 414-416 TO denotes to
T21595 404-413 VB denotes recruited
T21609 508-517 VB denotes resulting
T21608 506-507 -COMMA- denotes ,
T21607 499-506 NN denotes cIAP1/2
T21606 496-498 IN denotes of
R14175 T21693 T21691 arg1Of regulator,a
R14176 T21693 T21692 arg1Of regulator,negative
R14177 T21693 T21694 arg1Of regulator,of
R14009 T21534 T21532 arg1Of signalling,Noncanonical
R14010 T21534 T21533 arg1Of signalling,NF-κB
R14011 T21535 T21536 arg1Of CD40,and
R14012 T21536 T21538 arg1Of and,can
R14013 T21536 T21539 arg1Of and,activate
R14014 T21537 T21536 arg2Of RANK,and
R14015 T21539 T21538 arg2Of activate,can
R14016 T21543 T21539 arg2Of pathway,activate
R14017 T21543 T21540 arg1Of pathway,the
R14018 T21543 T21541 arg1Of pathway,noncanonical
R14019 T21543 T21542 arg1Of pathway,NF-κB
R14020 T21543 T21544 arg1Of pathway,that
R14021 T21543 T21545 arg1Of pathway,is
R14022 T21543 T21546 arg1Of pathway,dependent
R14023 T21546 T21545 arg2Of dependent,is
R14024 T21546 T21547 arg1Of dependent,on
R14025 T21548 T21547 arg2Of NF-κB,on
R14026 T21548 T21549 arg1Of NF-κB,inducing
R14027 T21552 T21551 arg2Of NIK,(
R14028 T21553 T21551 arg3Of ),(
R14029 T21555 T21549 arg2Of levels,inducing
R14030 T21555 T21550 arg1Of levels,kinase
R14031 T21555 T21551 arg1Of levels,(
R14032 T21555 T21554 arg1Of levels,expression
R14033 T21558 T21556 arg2Of cells,In
R14034 T21558 T21557 arg1Of cells,unstimulated
R14035 T21559 T21560 arg1Of NIK,forms
R14036 T21560 T21556 arg1Of forms,In
R14037 T21560 T21584 arg1Of forms,","
R14038 T21563 T21560 arg2Of complex,forms
R14039 T21563 T21561 arg1Of complex,a
R14040 T21563 T21562 arg1Of complex,cytosolic
R14041 T21563 T21564 arg1Of complex,with
R14042 T21567 T21565 arg1Of ligases,the
R14043 T21567 T21566 arg1Of ligases,ubiquitin
R14044 T21568 T21569 arg1Of TRAF2,","
R14045 T21569 T21571 arg1Of ",",and
R14046 T21570 T21569 arg2Of TRAF3,","
R14047 T21571 T21564 arg2Of and,with
R14048 T21571 T21567 arg1Of and,ligases
R14049 T21571 T21573 arg1Of and,","
R14050 T21571 T21574 arg1Of and,which
R14051 T21571 T21575 arg1Of and,facilitates
R14052 T21572 T21571 arg2Of cIAP1/2,and
R14053 T21577 T21578 arg1Of K48-linked,polyubiquitination
R14054 T21577 T21579 arg1Of K48-linked,and
R14055 T21580 T21579 arg2Of proteasomal,and
R14056 T21581 T21575 arg2Of degradation,facilitates
R14057 T21581 T21576 arg1Of degradation,the
R14058 T21581 T21577 arg1Of degradation,K48-linked
R14059 T21581 T21580 arg1Of degradation,proteasomal
R14060 T21581 T21582 arg1Of degradation,of
R14061 T21583 T21582 arg2Of NIK,of
R14062 T21585 T21560 arg3Of keeping,forms
R14063 T21587 T21585 arg2Of levels,keeping
R14064 T21587 T21586 arg1Of levels,NIK
R14065 T21587 T21588 arg1Of levels,low
R14066 T21588 T21585 arg3Of low,keeping
R14067 T21591 T21589 arg2Of binding,Upon
R14068 T21591 T21590 arg1Of binding,ligand
R14069 T21593 T21594 arg1Of TRAF3,is
R14070 T21593 T21595 arg2Of TRAF3,recruited
R14071 T21595 T21589 arg1Of recruited,Upon
R14072 T21595 T21592 arg1Of recruited,","
R14073 T21595 T21594 arg2Of recruited,is
R14074 T21595 T21596 arg1Of recruited,to
R14075 T21598 T21596 arg2Of receptor,to
R14076 T21598 T21597 arg1Of receptor,the
R14077 T21598 T21599 arg1Of receptor,","
R14078 T21598 T21600 arg1Of receptor,where
R14079 T21601 T21602 arg1Of TRAF2,directs
R14080 T21602 T21600 arg2Of directs,where
R14081 T21602 T21608 arg1Of directs,","
R14082 T21602 T21609 modOf directs,resulting
R14083 T21605 T21602 arg2Of polyubiquitination,directs
R14084 T21605 T21603 arg1Of polyubiquitination,nondegradative
R14085 T21605 T21604 arg1Of polyubiquitination,K63-linked
R14086 T21605 T21606 arg1Of polyubiquitination,of
R14087 T21607 T21606 arg2Of cIAP1/2,of
R14088 T21609 T21610 arg1Of resulting,in
R14089 T21612 T21610 arg2Of activation,in
R14090 T21612 T21611 arg1Of activation,their
R14091 T21614 T21613 arg1Of cIAP1/2,Subsequently
R14092 T21614 T21615 arg1Of cIAP1/2,directs
R14093 T21618 T21617 arg1Of polyubiquitination,K48-linked
R14094 T21618 T21619 arg1Of polyubiquitination,to
R14095 T21618 T21623 arg1Of polyubiquitination,than
R14096 T21620 T21619 arg2Of TRAF3,to
R14097 T21623 T21615 arg2Of than,directs
R14098 T21623 T21616 arg1Of than,its
R14099 T21623 T21621 arg1Of than,","
R14100 T21623 T21622 arg1Of than,rather
R14101 T21624 T21623 arg2Of NIK,than
R14102 T21627 T21625 arg2Of result,As
R14103 T21627 T21626 arg1Of result,a
R14104 T21629 T21630 arg1Of TRAF3,is
R14105 T21629 T21631 arg2Of TRAF3,degraded
R14106 T21631 T21630 arg2Of degraded,is
R14107 T21631 T21632 arg1Of degraded,and
R14108 T21632 T21625 arg1Of and,As
R14109 T21632 T21628 arg1Of and,","
R14110 T21632 T21636 arg1Of and,","
R14111 T21632 T21637 modOf and,resulting
R14112 T21633 T21634 arg1Of NIK,is
R14113 T21633 T21635 arg2Of NIK,stabilised
R14114 T21635 T21632 arg2Of stabilised,and
R14115 T21635 T21634 arg2Of stabilised,is
R14116 T21637 T21638 arg1Of resulting,in
R14117 T21641 T21638 arg2Of levels,in
R14118 T21641 T21639 arg2Of levels,increased
R14119 T21641 T21640 arg1Of levels,NIK
R14120 T21641 T21642 arg1Of levels,in
R14121 T21644 T21642 arg2Of cell,in
R14122 T21644 T21643 arg1Of cell,the
R14123 T21645 T21647 arg1Of NIK,phosphorylates
R14124 T21645 T21649 arg1Of NIK,activates
R14125 T21647 T21648 arg1Of phosphorylates,and
R14126 T21648 T21646 arg1Of and,then
R14127 T21649 T21648 arg2Of activates,and
R14128 T21650 T21647 arg2Of IKK1,phosphorylates
R14129 T21650 T21649 arg2Of IKK1,activates
R14130 T21650 T21651 arg1Of IKK1,","
R14131 T21650 T21652 arg1Of IKK1,which
R14132 T21650 T21653 arg1Of IKK1,mediates
R14133 T21656 T21653 arg2Of phosphorylation,mediates
R14134 T21656 T21654 arg1Of phosphorylation,NF-κB
R14135 T21656 T21655 arg1Of phosphorylation,p100
R14136 T21657 T21658 arg1Of This,is
R14137 T21657 T21659 arg2Of This,followed
R14138 T21659 T21658 arg2Of followed,is
R14139 T21661 T21662 arg1Of K48-linked,polyubiquitination
R14140 T21661 T21663 arg1Of K48-linked,and
R14141 T21665 T21663 arg2Of proteasomal,and
R14142 T21665 T21664 arg1Of proteasomal,partial
R14143 T21666 T21659 arg1Of degradation,followed
R14144 T21666 T21660 arg2Of degradation,by
R14145 T21666 T21661 arg1Of degradation,K48-linked
R14146 T21666 T21665 arg1Of degradation,proteasomal
R14147 T21666 T21667 arg1Of degradation,of
R14148 T21666 T21671 arg1Of degradation,","
R14149 T21666 T21672 arg1Of degradation,which
R14150 T21666 T21673 arg1Of degradation,forms
R14151 T21668 T21667 arg2Of p100,of
R14152 T21668 T21669 arg1Of p100,to
R14153 T21670 T21669 arg2Of p52,to
R14154 T21675 T21673 arg2Of heterodimer,forms
R14155 T21675 T21674 arg1Of heterodimer,a
R14156 T21675 T21676 arg1Of heterodimer,with
R14157 T21675 T21678 modOf heterodimer,to
R14158 T21677 T21676 arg2Of RelB,with
R14159 T21679 T21678 arg1Of activate,to
R14160 T21680 T21679 arg2Of transcription,activate
R14161 T21681 T21682 arg1Of Next,to
R14162 T21683 T21682 arg2Of TRAF3,to
R14163 T21685 T21686 arg1Of TRAF1,has
R14164 T21685 T21688 arg1Of TRAF1,been
R14165 T21685 T21689 arg2Of TRAF1,identified
R14166 T21689 T21681 arg1Of identified,Next
R14167 T21689 T21684 arg1Of identified,","
R14168 T21689 T21686 arg2Of identified,has
R14169 T21689 T21687 arg1Of identified,also
R14170 T21689 T21688 arg2Of identified,been
R14171 T21689 T21690 arg1Of identified,as
R14172 T21689 T21697 arg1Of identified,","
R14173 T21689 T21700 arg1Of identified,by
R14174 T21693 T21690 arg2Of regulator,as
R14178 T21696 T21694 arg2Of pathway,of
R14179 T21696 T21695 arg1Of pathway,this
R14180 T21699 T21698 arg1Of probably,most
R14181 T21700 T21699 arg1Of by,probably
R14182 T21701 T21700 arg2Of competing,by
R14183 T21701 T21702 arg1Of competing,with
R14184 T21701 T21718 arg1Of competing,;
R14185 T21707 T21702 arg2Of cIAP,with
R14186 T21707 T21703 arg1Of cIAP,other
R14187 T21707 T21704 arg1Of cIAP,TNF
R14188 T21707 T21705 arg1Of cIAP,receptor-associated
R14189 T21707 T21706 arg1Of cIAP,factors.
R14190 T21707 T21708 arg1Of cIAP,","
R14191 T21707 T21713 arg1Of cIAP,;
R14192 T21710 T21708 arg2Of inhibitor,","
R14193 T21710 T21709 arg1Of inhibitor,cellular
R14194 T21710 T21711 arg1Of inhibitor,of
R14195 T21712 T21711 arg2Of apoptosis,of
R14196 T21714 T21713 arg2Of IKK,;
R14197 T21714 T21715 arg1Of IKK,","
R14198 T21717 T21715 arg2Of kinase,","
R14199 T21717 T21716 arg1Of kinase,IκB
R14200 T21719 T21689 arg3Of NF,identified
R14201 T21719 T21720 arg1Of NF,","
R14202 T21719 T21723 arg1Of NF,;
R14203 T21722 T21720 arg2Of factor,","
R14204 T21722 T21721 arg1Of factor,nuclear
R14205 T21724 T21723 arg2Of RANK,;
R14206 T21724 T21725 arg1Of RANK,","
R14207 T21724 T21730 arg1Of RANK,;
R14208 T21727 T21725 arg2Of activator,","
R14209 T21727 T21726 arg1Of activator,receptor
R14210 T21727 T21728 arg1Of activator,of
R14211 T21729 T21728 arg2Of NF-κB,of
R14212 T21731 T21730 arg2Of TRAF,;
R14213 T21731 T21732 arg1Of TRAF,","
R14214 T21731 T21736 arg1Of TRAF,;
R14215 T21735 T21732 arg2Of factor,","
R14216 T21735 T21733 arg1Of factor,TNF
R14217 T21735 T21734 arg1Of factor,receptor-associated
R14218 T21737 T21736 arg2Of TNF,;
R14219 T21737 T21738 arg1Of TNF,","
R14220 T21741 T21738 arg2Of factor,","
R14221 T21741 T21739 arg1Of factor,tumour
R14222 T21741 T21740 arg1Of factor,necrosis

GO-BP

Id Subject Object Predicate Lexical cue
T21763 1301-1309 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T21762 1301-1309 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T21761 1301-1309 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T21760 1301-1309 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T21759 1231-1249 http://purl.obolibrary.org/obo/GO_0051092 denotes activator of NF-κB
T21758 1179-1182 http://purl.obolibrary.org/obo/GO_0008384 denotes IKK
T21757 1168-1177 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T21756 1168-1177 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T21755 1146-1154 http://purl.obolibrary.org/obo/GO_0007349 denotes cellular
T21754 967-980 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T21753 800-815 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T21752 891-902 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T21751 330-341 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T21750 730-733 http://purl.obolibrary.org/obo/GO_0004704 denotes NIK
T21749 706-709 http://purl.obolibrary.org/obo/GO_0004704 denotes NIK
T21748 664-667 http://purl.obolibrary.org/obo/GO_0004704 denotes NIK
T21747 624-627 http://purl.obolibrary.org/obo/GO_0004704 denotes NIK
T21746 358-361 http://purl.obolibrary.org/obo/GO_0004704 denotes NIK
T21745 345-348 http://purl.obolibrary.org/obo/GO_0004704 denotes NIK
T21744 179-182 http://purl.obolibrary.org/obo/GO_0004704 denotes NIK
T21743 133-136 http://purl.obolibrary.org/obo/GO_0004704 denotes NIK
T21742 19-29 http://purl.obolibrary.org/obo/GO_0023052 denotes signalling

GO-MF

Id Subject Object Predicate Lexical cue
T21775 1179-1182 http://purl.obolibrary.org/obo/GO_0008384 denotes IKK
T21774 386-393 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T21773 379-385 http://purl.obolibrary.org/obo/GO_0005488 denotes ligand
T21772 218-227 http://purl.obolibrary.org/obo/GO_0031386 denotes ubiquitin
T21771 730-733 http://purl.obolibrary.org/obo/GO_0004704 denotes NIK
T21770 706-709 http://purl.obolibrary.org/obo/GO_0004704 denotes NIK
T21769 664-667 http://purl.obolibrary.org/obo/GO_0004704 denotes NIK
T21768 624-627 http://purl.obolibrary.org/obo/GO_0004704 denotes NIK
T21767 358-361 http://purl.obolibrary.org/obo/GO_0004704 denotes NIK
T21766 345-348 http://purl.obolibrary.org/obo/GO_0004704 denotes NIK
T21765 179-182 http://purl.obolibrary.org/obo/GO_0004704 denotes NIK
T21764 133-136 http://purl.obolibrary.org/obo/GO_0004704 denotes NIK

GO-CC

Id Subject Object Predicate Lexical cue
T21779 201-235 http://purl.obolibrary.org/obo/GO_0000153 denotes complex with the ubiquitin ligases
T21778 201-235 http://purl.obolibrary.org/obo/GO_0000151 denotes complex with the ubiquitin ligases
T21777 724-728 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T21776 173-178 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T21785 201-235 http://purl.obolibrary.org/obo/GO_0000836 denotes complex with the ubiquitin ligases
T21784 201-235 http://purl.obolibrary.org/obo/GO_0043494 denotes complex with the ubiquitin ligases
T21783 201-235 http://purl.obolibrary.org/obo/GO_0019005 denotes complex with the ubiquitin ligases
T21782 201-235 http://purl.obolibrary.org/obo/GO_0000152 denotes complex with the ubiquitin ligases
T21781 201-235 http://purl.obolibrary.org/obo/GO_0000837 denotes complex with the ubiquitin ligases
T21780 201-235 http://purl.obolibrary.org/obo/GO_0000835 denotes complex with the ubiquitin ligases

sentences

Id Subject Object Predicate Lexical cue
T21404 374-538 Sentence denotes Upon ligand binding, TRAF3 is recruited to the receptor, where TRAF2 directs nondegradative K63-linked polyubiquitination of cIAP1/2, resulting in their activation.
T21403 157-373 Sentence denotes In unstimulated cells NIK forms a cytosolic complex with the ubiquitin ligases TRAF2, TRAF3 and cIAP1/2, which facilitates the K48-linked polyubiquitination and proteasomal degradation of NIK, keeping NIK levels low.
T21402 31-156 Sentence denotes CD40 and RANK can activate the noncanonical NF-κB pathway that is dependent on NF-κB inducing kinase (NIK) expression levels.
T21401 0-30 Sentence denotes Noncanonical NF-κB signalling.
T21409 982-1317 Sentence denotes Next to TRAF3, TRAF1 has also been identified as a negative regulator of this pathway, most probably by competing with other TNF receptor-associated factors. cIAP, cellular inhibitor of apoptosis; IKK, IκB kinase; NF, nuclear factor; RANK, receptor activator of NF-κB; TRAF, TNF receptor-associated factor; TNF, tumour necrosis factor.
T21408 817-981 Sentence denotes This is followed by K48-linked polyubiquitination and partial proteasomal degradation of p100 to p52, which forms a heterodimer with RelB to activate transcription.
T21407 730-816 Sentence denotes NIK then phosphorylates and activates IKK1, which mediates NF-κB p100 phosphorylation.
T21406 629-729 Sentence denotes As a result, TRAF3 is degraded and NIK is stabilised, resulting in increased NIK levels in the cell.
T21405 539-628 Sentence denotes Subsequently cIAP1/2 directs its K48-linked polyubiquitination to TRAF3, rather than NIK.
T75 31-156 Sentence denotes CD40 and RANK can activate the noncanonical NF-κB pathway that is dependent on NF-κB inducing kinase (NIK) expression levels.
T76 157-373 Sentence denotes In unstimulated cells NIK forms a cytosolic complex with the ubiquitin ligases TRAF2, TRAF3 and cIAP1/2, which facilitates the K48-linked polyubiquitination and proteasomal degradation of NIK, keeping NIK levels low.
T77 374-538 Sentence denotes Upon ligand binding, TRAF3 is recruited to the receptor, where TRAF2 directs nondegradative K63-linked polyubiquitination of cIAP1/2, resulting in their activation.
T78 539-628 Sentence denotes Subsequently cIAP1/2 directs its K48-linked polyubiquitination to TRAF3, rather than NIK.
T79 629-729 Sentence denotes As a result, TRAF3 is degraded and NIK is stabilised, resulting in increased NIK levels in the cell.
T80 730-816 Sentence denotes NIK then phosphorylates and activates IKK1, which mediates NF-κB p100 phosphorylation.
T81 817-981 Sentence denotes This is followed by K48-linked polyubiquitination and partial proteasomal degradation of p100 to p52, which forms a heterodimer with RelB to activate transcription.
T82 982-1317 Sentence denotes Next to TRAF3, TRAF1 has also been identified as a negative regulator of this pathway, most probably by competing with other TNF receptor-associated factors. cIAP, cellular inhibitor of apoptosis; IKK, IκB kinase; NF, nuclear factor; RANK, receptor activator of NF-κB; TRAF, TNF receptor-associated factor; TNF, tumour necrosis factor.

simple1

Id Subject Object Predicate Lexical cue
T21825 236-241 Protein denotes TRAF2
T21824 179-182 Protein denotes NIK
T21823 133-136 Protein denotes NIK
T21822 110-131 Protein denotes NF-κB inducing kinase
T21821 40-44 Protein denotes RANK
T21820 31-35 Protein denotes CD40
T21853 1294-1316 Protein denotes tumour necrosis factor
T21852 1289-1292 Protein denotes TNF
T21851 1222-1249 Protein denotes receptor activator of NF-κB
T21850 1216-1220 Protein denotes RANK
T21849 997-1002 Protein denotes TRAF1
T21848 990-995 Protein denotes TRAF3
T21847 950-954 Protein denotes RelB
T21846 914-917 Protein denotes p52
T21845 906-910 Protein denotes p100
T21844 795-799 Protein denotes p100
T21843 768-772 Protein denotes IKK1
T21842 730-733 Protein denotes NIK
T21841 706-709 Protein denotes NIK
T21840 664-667 Protein denotes NIK
T21839 642-647 Protein denotes TRAF3
T21838 624-627 Protein denotes NIK
T21837 605-610 Protein denotes TRAF3
T21836 558-559 Protein denotes 2
T21835 552-557 Protein denotes cIAP1
T21834 505-506 Protein denotes 2
T21833 499-504 Protein denotes cIAP1
T21832 437-442 Protein denotes TRAF2
T21831 395-400 Protein denotes TRAF3
T21830 358-361 Protein denotes NIK
T21829 345-348 Protein denotes NIK
T21828 259-260 Protein denotes 2
T21827 253-258 Protein denotes cIAP1
T21826 243-248 Protein denotes TRAF3

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T22376 253-258 Protein denotes cIAP1
T22375 243-248 Protein denotes TRAF3
T22374 236-241 Protein denotes TRAF2
T22373 179-182 Protein denotes NIK
T22372 358-361 Protein denotes NIK
T22371 345-348 Protein denotes NIK
T22370 133-136 Protein denotes NIK
T22369 110-131 Protein denotes NF-κB inducing kinase
T22368 40-44 Protein denotes RANK
T22367 31-35 Protein denotes CD40
T22418 891-902 Protein_catabolism denotes degradation
T22417 800-815 Phosphorylation denotes phosphorylation
T22416 758-767 Positive_regulation denotes activates
T22415 739-753 Phosphorylation denotes phosphorylates
T22414 780-788 Positive_regulation denotes mediates
T22413 683-692 Positive_regulation denotes resulting
T22412 634-640 Positive_regulation denotes result
T22411 651-659 Protein_catabolism denotes degraded
T22410 696-705 Positive_regulation denotes increased
T22409 671-681 Positive_regulation denotes stabilised
T22408 583-601 Binding denotes polyubiquitination
T22407 404-413 Binding denotes recruited
T22406 477-495 Binding denotes polyubiquitination
T22405 295-313 Binding denotes polyubiquitination
T22404 330-341 Protein_catabolism denotes degradation
T22403 268-279 Positive_regulation denotes facilitates
T22402 97-106 Regulation denotes dependent
T22401 138-148 Gene_expression denotes expression
T22400 1294-1316 Protein denotes tumour necrosis factor
T22399 1289-1292 Protein denotes TNF
T22398 1222-1249 Protein denotes receptor activator of NF-κB
T22397 1216-1220 Protein denotes RANK
T22396 997-1002 Protein denotes TRAF1
T22395 990-995 Protein denotes TRAF3
T22394 950-954 Protein denotes RelB
T22393 914-917 Protein denotes p52
T22392 906-910 Protein denotes p100
T22391 795-799 Protein denotes p100
T22390 768-772 Protein denotes IKK1
T22389 730-733 Protein denotes NIK
T22388 706-709 Protein denotes NIK
T22387 664-667 Protein denotes NIK
T22386 642-647 Protein denotes TRAF3
T22385 624-627 Protein denotes NIK
T22384 605-610 Protein denotes TRAF3
T22383 558-559 Protein denotes 2
T22382 552-557 Protein denotes cIAP1
T22381 505-506 Protein denotes 2
T22380 499-504 Protein denotes cIAP1
T22379 437-442 Protein denotes TRAF2
T22378 395-400 Protein denotes TRAF3
T22377 259-260 Protein denotes 2
R14569 T22369 T22402 themeOf NF-κB inducing kinase,dependent
R14570 T22369 T22401 themeOf NF-κB inducing kinase,expression
R14571 T22370 T22401 themeOf NIK,expression
R14572 T22371 T22405 themeOf NIK,polyubiquitination
R14573 T22371 T22404 themeOf NIK,degradation
R14575 T22380 T22406 themeOf cIAP1,polyubiquitination
R14591 T22404 T22403 themeOf degradation,facilitates
R14592 T22405 T22403 themeOf polyubiquitination,facilitates
R14574 T22378 T22407 themeOf TRAF3,recruited
R14576 T22381 T22406 themeOf 2,polyubiquitination
R14577 T22382 T22408 themeOf cIAP1,polyubiquitination
R14578 T22384 T22408 themeOf TRAF3,polyubiquitination
R14579 T22385 T22408 themeOf NIK,polyubiquitination
R14580 T22386 T22411 themeOf TRAF3,degraded
R14581 T22387 T22409 themeOf NIK,stabilised
R14582 T22388 T22413 themeOf NIK,resulting
R14583 T22388 T22410 themeOf NIK,increased
R14584 T22389 T22415 themeOf NIK,phosphorylates
R14585 T22389 T22416 causeOf NIK,activates
R14586 T22390 T22415 themeOf IKK1,phosphorylates
R14587 T22390 T22416 themeOf IKK1,activates
R14588 T22391 T22417 themeOf p100,phosphorylation
R14589 T22392 T22418 themeOf p100,degradation
R14590 T22393 T22418 themeOf p52,degradation
R14593 T22411 T22412 themeOf degraded,result
R14594 T22417 T22414 themeOf phosphorylation,mediates

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T22109 110-131 Protein denotes NF-κB inducing kinase
T22108 40-44 Protein denotes RANK
T22107 31-35 Protein denotes CD40
T22155 891-902 Protein_catabolism denotes degradation
T22154 758-767 Positive_regulation denotes activates
T22153 739-753 Phosphorylation denotes phosphorylates
T22152 800-815 Phosphorylation denotes phosphorylation
T22151 780-788 Positive_regulation denotes mediates
T22150 696-705 Positive_regulation denotes increased
T22149 651-659 Protein_catabolism denotes degraded
T22147 477-495 Binding denotes polyubiquitination
T22146 527-537 Positive_regulation denotes activation
T22145 404-413 Binding denotes recruited
T22144 330-341 Protein_catabolism denotes degradation
T22143 295-313 Binding denotes polyubiquitination
T22142 138-148 Gene_expression denotes expression
T22141 97-106 Regulation denotes dependent
T22140 1294-1316 Protein denotes tumour necrosis factor
T22139 1289-1292 Protein denotes TNF
T22138 1222-1249 Protein denotes receptor activator of NF-κB
T22137 1216-1220 Protein denotes RANK
T22136 997-1002 Protein denotes TRAF1
T22135 990-995 Protein denotes TRAF3
T22134 950-954 Protein denotes RelB
T22133 914-917 Protein denotes p52
T22132 906-910 Protein denotes p100
T22131 795-799 Protein denotes p100
T22130 768-772 Protein denotes IKK1
T22129 730-733 Protein denotes NIK
T22128 706-709 Protein denotes NIK
T22127 664-667 Protein denotes NIK
T22126 642-647 Protein denotes TRAF3
T22125 624-627 Protein denotes NIK
T22124 605-610 Protein denotes TRAF3
T22123 558-559 Protein denotes 2
T22122 552-557 Protein denotes cIAP1
T22121 505-506 Protein denotes 2
T22120 499-504 Protein denotes cIAP1
T22119 437-442 Protein denotes TRAF2
T22118 395-400 Protein denotes TRAF3
T22117 259-260 Protein denotes 2
T22116 253-258 Protein denotes cIAP1
T22115 243-248 Protein denotes TRAF3
T22114 236-241 Protein denotes TRAF2
T22113 179-182 Protein denotes NIK
T22112 358-361 Protein denotes NIK
T22111 345-348 Protein denotes NIK
T22110 133-136 Protein denotes NIK
T22148 583-601 Binding denotes polyubiquitination
R14446 T22109 T22141 themeOf NF-κB inducing kinase,dependent
R14447 T22109 T22142 themeOf NF-κB inducing kinase,expression
R14448 T22110 T22142 themeOf NIK,expression
R14449 T22111 T22143 themeOf NIK,polyubiquitination
R14450 T22111 T22144 themeOf NIK,degradation
R14451 T22118 T22145 themeOf TRAF3,recruited
R14452 T22120 T22147 themeOf cIAP1,polyubiquitination
R14453 T22120 T22146 themeOf cIAP1,activation
R14454 T22121 T22147 themeOf 2,polyubiquitination
R14455 T22124 T22148 themeOf TRAF3,polyubiquitination
R14456 T22125 T22148 themeOf NIK,polyubiquitination
R14457 T22126 T22149 themeOf TRAF3,degraded
R14458 T22128 T22150 themeOf NIK,increased
R14459 T22129 T22153 themeOf NIK,phosphorylates
R14460 T22129 T22154 causeOf NIK,activates
R14461 T22130 T22153 themeOf IKK1,phosphorylates
R14462 T22130 T22154 themeOf IKK1,activates
R14463 T22130 T22151 causeOf IKK1,mediates
R14464 T22131 T22152 themeOf p100,phosphorylation
R14465 T22132 T22155 themeOf p100,degradation
R14466 T22133 T22155 themeOf p52,degradation
R14467 T22142 T22141 themeOf expression,dependent
R14468 T22142 T22141 themeOf expression,dependent
R14469 T22152 T22151 themeOf phosphorylation,mediates

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T22486 642-659 Protein_catabolism denotes TRAF3 is degraded
T22485 107-148 Gene_expression denotes on NF-κB inducing kinase (NIK) expression
T22484 789-815 Phosphorylation denotes NF-κB p100 phosphorylation
T22483 318-372 Protein_catabolism denotes proteasomal degradation of NIK, keeping NIK levels low
T22482 379-403 Binding denotes ligand binding, TRAF3 is
T22481 568-601 Binding denotes its K48-linked polyubiquitination
T22480 871-918 Protein_catabolism denotes partial proteasomal degradation of p100 to p52,
T22479 431-537 Regulation denotes where TRAF2 directs nondegradative K63-linked polyubiquitination of cIAP1/2, resulting in their activation
T22478 730-773 Positive_regulation denotes NIK then phosphorylates and activates IKK1,
T22477 539-627 Regulation denotes Subsequently cIAP1/2 directs its K48-linked polyubiquitination to TRAF3, rather than NIK
T22476 774-815 Regulation denotes which mediates NF-κB p100 phosphorylation
T22475 664-681 Regulation denotes NIK is stabilised
T22474 1257-1292 Binding denotes TNF receptor-associated factor; TNF
T22473 1257-1260 Protein denotes TNF
T22472 1140-1144 Protein denotes cIAP
T22471 58-148 Protein denotes the noncanonical NF-κB pathway that is dependent on NF-κB inducing kinase (NIK) expression
T22470 379-385 Entity denotes ligand
T22469 911-918 Protein denotes to p52,
T22468 945-954 Protein denotes with RelB
T22467 110-137 Protein denotes NF-κB inducing kinase (NIK)
T22466 642-647 Protein denotes TRAF3
T22465 572-582 Entity denotes K48-linked
T22464 284-294 Entity denotes K48-linked
T22463 552-559 Protein denotes cIAP1/2
T22462 730-733 Protein denotes NIK
T22461 1216-1221 Protein denotes RANK,
T22460 605-610 Protein denotes TRAF3
T22459 160-178 Entity denotes unstimulated cells
T22458 1111-1130 Protein denotes receptor-associated
T22457 789-794 Protein denotes NF-κB
T22456 990-995 Protein denotes TRAF3
T22455 558-559 Protein denotes 2
T22454 133-136 Protein denotes NIK
T22453 243-248 Protein denotes TRAF3
T22452 997-1002 Protein denotes TRAF1
T22451 552-559 Protein denotes cIAP1/2
T22450 720-728 Entity denotes the cell
T22449 768-773 Protein denotes IKK1,
T22448 499-537 Protein denotes cIAP1/2, resulting in their activation
T22447 1257-1280 Protein denotes TNF receptor-associated
T22446 1251-1293 Protein denotes TRAF, TNF receptor-associated factor; TNF,
T22445 903-910 Protein denotes of p100
T22444 1257-1292 Protein denotes TNF receptor-associated factor; TNF
T22443 214-241 Protein denotes the ubiquitin ligases TRAF2
T22442 253-261 Protein denotes cIAP1/2,
T22441 624-627 Protein denotes NIK
T22440 189-261 Entity denotes a cytosolic complex with the ubiquitin ligases TRAF2, TRAF3 and cIAP1/2,
T22439 1196-1316 Protein denotes NF, nuclear factor; RANK, receptor activator of NF-κB; TRAF, TNF receptor-associated factor; TNF, tumour necrosis factor
T22438 437-442 Protein denotes TRAF2
T22437 706-709 Protein denotes NIK
T22436 358-361 Protein denotes NIK
T22435 40-44 Protein denotes RANK
T22434 1107-1110 Protein denotes TNF
T22433 1146-1194 Entity denotes cellular inhibitor of apoptosis; IKK, IκB kinase
T22432 1196-1316 Protein denotes NF, nuclear factor; RANK, receptor activator of NF-κB; TRAF, TNF receptor-associated factor; TNF, tumour necrosis factor
T22431 395-400 Protein denotes TRAF3
T22430 31-35 Protein denotes CD40
T22429 664-667 Protein denotes NIK
T22428 931-980 Entity denotes a heterodimer with RelB to activate transcription
T22427 179-182 Protein denotes NIK
T22426 342-372 Protein denotes of NIK, keeping NIK levels low
T22425 214-241 Protein denotes the ubiquitin ligases TRAF2
T22424 1168-1194 Protein denotes apoptosis; IKK, IκB kinase
T22423 789-799 Protein denotes NF-κB p100
T22422 417-430 Protein denotes the receptor,
T22421 218-227 Protein denotes ubiquitin
T22420 837-847 Entity denotes K48-linked
T22419 466-476 Entity denotes K63-linked
R14595 T22423 T22484 themeOf NF-κB p100,NF-κB p100 phosphorylation
R14596 T22426 T22483 themeOf "of NIK, keeping NIK levels low","proteasomal degradation of NIK, keeping NIK levels low"
R14597 T22429 T22475 themeOf NIK,NIK is stabilised
R14598 T22438 T22479 causeOf TRAF2,"where TRAF2 directs nondegradative K63-linked polyubiquitination of cIAP1/2, resulting in their activation"
R14599 T22444 T22474 themeOf TNF receptor-associated factor; TNF,TNF receptor-associated factor; TNF
R14600 T22445 T22480 themeOf of p100,"partial proteasomal degradation of p100 to p52,"
R14601 T22447 T22474 themeOf TNF receptor-associated,TNF receptor-associated factor; TNF
R14602 T22449 T22478 themeOf "IKK1,","NIK then phosphorylates and activates IKK1,"
R14603 T22462 T22478 causeOf NIK,"NIK then phosphorylates and activates IKK1,"
R14604 T22463 T22477 causeOf cIAP1/2,"Subsequently cIAP1/2 directs its K48-linked polyubiquitination to TRAF3, rather than NIK"
R14605 T22465 T22481 themeOf K48-linked,its K48-linked polyubiquitination
R14606 T22466 T22486 themeOf TRAF3,TRAF3 is degraded
R14607 T22467 T22485 themeOf NF-κB inducing kinase (NIK),on NF-κB inducing kinase (NIK) expression
R14608 T22484 T22476 themeOf NF-κB p100 phosphorylation,which mediates NF-κB p100 phosphorylation

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T22308 1294-1316 Protein denotes tumour necrosis factor
T22307 1289-1292 Protein denotes TNF
T22306 1257-1287 Protein denotes TNF receptor-associated factor
T22305 1251-1255 Protein denotes TRAF
T22304 1244-1249 Protein denotes NF-κB
T22303 1216-1220 Protein denotes RANK
T22302 1196-1214 Protein denotes NF, nuclear factor
T22301 1184-1194 Protein denotes IκB kinase
T22300 1179-1182 Protein denotes IKK
T22299 1086-1095 Binding denotes competing
T22277 706-709 Protein denotes NIK
T22276 664-667 Protein denotes NIK
T22275 642-647 Protein denotes TRAF3
T22274 624-627 Protein denotes NIK
T22273 605-610 Protein denotes TRAF3
T22272 404-413 Binding denotes recruited
T22271 386-393 Binding denotes binding
T22270 499-506 Protein denotes cIAP1/2
T22269 437-442 Protein denotes TRAF2
T22268 395-400 Protein denotes TRAF3
T22267 330-341 Protein_catabolism denotes degradation
T22266 358-361 Protein denotes NIK
T22265 345-348 Protein denotes NIK
T22264 253-260 Protein denotes cIAP1/2
T22263 243-248 Protein denotes TRAF3
T22262 236-241 Protein denotes TRAF2
T22261 218-227 Protein denotes ubiquitin
T22260 97-106 Positive_regulation denotes dependent
T22259 97-106 Positive_regulation denotes dependent
T22258 138-148 Gene_expression denotes expression
T22257 138-148 Gene_expression denotes expression
T22256 133-136 Protein denotes NIK
T22255 110-131 Protein denotes NF-κB inducing kinase
T22254 75-80 Protein denotes NF-κB
T22253 40-44 Protein denotes RANK
T22252 31-35 Protein denotes CD40
T22251 13-18 Protein denotes NF-κB
T22286 800-815 Phosphorylation denotes phosphorylation
T22285 758-767 Positive_regulation denotes activates
T22284 739-753 Phosphorylation denotes phosphorylates
T22283 795-799 Protein denotes p100
T22282 789-794 Protein denotes NF-κB
T22281 768-772 Protein denotes IKK1
T22280 730-733 Protein denotes NIK
T22279 696-705 Positive_regulation denotes increased
T22278 651-659 Protein_catabolism denotes degraded
T22298 1107-1138 Protein denotes TNF receptor-associated factors
T22297 997-1002 Protein denotes TRAF1
T22296 990-995 Protein denotes TRAF3
T22295 933-944 Binding denotes heterodimer
T22294 891-902 Protein_catabolism denotes degradation
T22293 891-902 Protein_catabolism denotes degradation
T22292 950-954 Protein denotes RelB
T22291 914-917 Protein denotes p52
T22290 906-910 Protein denotes p100
T22289 780-788 Positive_regulation denotes mediates
T22288 780-788 Positive_regulation denotes mediates
T22287 800-815 Phosphorylation denotes phosphorylation
R14523 T22255 T22257 themeOf NF-κB inducing kinase,expression
R14524 T22256 T22258 themeOf NIK,expression
R14525 T22257 T22259 themeOf expression,dependent
R14526 T22258 T22260 themeOf expression,dependent
R14527 T22265 T22267 themeOf NIK,degradation
R14528 T22268 T22271 themeOf TRAF3,binding
R14529 T22268 T22272 themeOf TRAF3,recruited
R14530 T22275 T22278 themeOf TRAF3,degraded
R14531 T22277 T22279 themeOf NIK,increased
R14532 T22280 T22284 themeOf NIK,phosphorylates
R14533 T22281 T22285 themeOf IKK1,activates
R14534 T22282 T22286 themeOf NF-κB,phosphorylation
R14535 T22283 T22287 themeOf p100,phosphorylation
R14536 T22285 T22280 Cause activates,NIK
R14537 T22286 T22288 themeOf phosphorylation,mediates
R14538 T22287 T22289 themeOf phosphorylation,mediates
R14539 T22288 T22281 Cause mediates,IKK1
R14540 T22289 T22281 Cause mediates,IKK1
R14541 T22290 T22293 themeOf p100,degradation
R14542 T22291 T22294 themeOf p52,degradation
R14543 T22292 T22295 themeOf RelB,heterodimer
R14544 T22297 T22299 themeOf TRAF1,competing
R14545 T22298 T22299 themeOf TNF receptor-associated factors,competing

test3

Id Subject Object Predicate Lexical cue
T21400 1294-1316 Protein denotes tumour necrosis factor
T21399 1289-1292 Protein denotes TNF
T21398 1222-1249 Protein denotes receptor activator of NF-κB
T21397 1216-1220 Protein denotes RANK
T21396 997-1002 Protein denotes TRAF1
T21395 990-995 Protein denotes TRAF3
T21394 950-954 Protein denotes RelB
T21393 914-917 Protein denotes p52
T21392 906-910 Protein denotes p100
T21391 891-902 Protein_catabolism denotes degradation
T21390 800-815 Phosphorylation denotes phosphorylation
T21389 795-799 Protein denotes p100
T21388 780-788 Positive_regulation denotes mediates
T21387 768-772 Protein denotes IKK1
T21386 758-767 Positive_regulation denotes activates
T21385 730-733 Protein denotes NIK
T21384 706-709 Protein denotes NIK
T21383 664-667 Protein denotes NIK
T21382 651-659 Protein_catabolism denotes degraded
T21381 642-647 Protein denotes TRAF3
T21380 624-627 Protein denotes NIK
T21379 605-610 Protein denotes TRAF3
T21378 558-559 Protein denotes 2
T21377 552-557 Protein denotes cIAP1
T21376 505-506 Protein denotes 2
T21375 499-504 Protein denotes cIAP1
T21374 437-442 Protein denotes TRAF2
T21373 404-413 Binding denotes recruited
T21372 395-400 Protein denotes TRAF3
T21371 386-393 Binding denotes binding
T21370 358-361 Protein denotes NIK
T21369 345-348 Protein denotes NIK
T21368 330-341 Protein_catabolism denotes degradation
T21367 259-260 Protein denotes 2
T21366 253-258 Protein denotes cIAP1
T21365 243-248 Protein denotes TRAF3
T21364 236-241 Protein denotes TRAF2
T21363 179-182 Protein denotes NIK
T21362 133-136 Protein denotes NIK
T21361 110-131 Protein denotes NF-κB inducing kinase
T21360 40-44 Protein denotes RANK
T21359 31-35 Protein denotes CD40
T21358 1294-1316 Protein denotes tumour necrosis factor
T21357 1289-1292 Protein denotes TNF
T21356 1222-1249 Protein denotes receptor activator of NF-κB
T21355 1216-1220 Protein denotes RANK
T21354 997-1002 Protein denotes TRAF1
T21353 990-995 Protein denotes TRAF3
T21352 950-954 Protein denotes RelB
T21351 914-917 Protein denotes p52
T21350 906-910 Protein denotes p100
T21349 795-799 Protein denotes p100
T21348 768-772 Protein denotes IKK1
T21347 730-733 Protein denotes NIK
T21346 706-709 Protein denotes NIK
T21345 664-667 Protein denotes NIK
T21344 642-647 Protein denotes TRAF3
T21343 624-627 Protein denotes NIK
T21342 605-610 Protein denotes TRAF3
T21341 558-559 Protein denotes 2
T21340 552-557 Protein denotes cIAP1
T21339 505-506 Protein denotes 2
T21338 499-504 Protein denotes cIAP1
T21337 437-442 Protein denotes TRAF2
T21336 395-400 Protein denotes TRAF3
T21335 358-361 Protein denotes NIK
T21334 345-348 Protein denotes NIK
T21333 259-260 Protein denotes 2
T21332 253-258 Protein denotes cIAP1
T21331 243-248 Protein denotes TRAF3
T21330 236-241 Protein denotes TRAF2
T21329 179-182 Protein denotes NIK
T21328 133-136 Protein denotes NIK
T21327 110-131 Protein denotes NF-κB inducing kinase
T21326 40-44 Protein denotes RANK
T21325 31-35 Protein denotes CD40
R13918 T21362 T21361 equivalentTo NIK,NF-κB inducing kinase
R13919 T21369 T21368 themeOf NIK,degradation
R13920 T21372 T21371 themeOf TRAF3,binding
R13921 T21372 T21373 themeOf TRAF3,recruited
R13922 T21381 T21382 themeOf TRAF3,degraded
R13923 T21385 T21386 causeOf NIK,activates
R13924 T21385 T21388 causeOf NIK,mediates
R13925 T21387 T21386 themeOf IKK1,activates
R13926 T21387 T21388 causeOf IKK1,mediates
R13927 T21389 T21390 themeOf p100,phosphorylation
R13928 T21390 T21388 themeOf phosphorylation,mediates
R13929 T21392 T21391 themeOf p100,degradation
R13930 T21393 T21391 themeOf p52,degradation
R13931 T21394 T21391 themeOf RelB,degradation