PMC:3191169 / 5981-6697 JSONTXT

{"project":"2_test","denotations":[{"id":"22022520-15837932-87377367","span":{"begin":173,"end":175},"obj":"15837932"},{"id":"22022520-16415869-87377368","span":{"begin":179,"end":181},"obj":"16415869"},{"id":"22022520-15837932-87377369","span":{"begin":376,"end":378},"obj":"15837932"},{"id":"22022520-16415869-87377370","span":{"begin":382,"end":384},"obj":"16415869"},{"id":"22022520-15996548-87377371","span":{"begin":468,"end":470},"obj":"15996548"},{"id":"T29903","span":{"begin":173,"end":175},"obj":"15837932"},{"id":"T44655","span":{"begin":179,"end":181},"obj":"16415869"},{"id":"T19544","span":{"begin":376,"end":378},"obj":"15837932"},{"id":"T13425","span":{"begin":382,"end":384},"obj":"16415869"},{"id":"T54213","span":{"begin":468,"end":470},"obj":"15996548"}],"text":"Animals\nSrf (flex1neo/flex1neo) and Camk2α-iCre mice were bred to obtain Srf mutants (Srf–/–; Camk2a-iCre) or control littermates (Srf –/–, Srf +/– or Srf +/–; Camk2α-iCre [35], [36]). Recombination induced by Cre recombinase expression via the Camk2α promoter starts just before birth and results in strong SRF down-regulation at time-points used to culture primary neurons [35], [36]. EphA7 mice were kindly provided by U. Drescher (King's College, London, UK; see [15]). Animal experiments and housing were approved by the local ethics committee (Einrichtung für Tierschutz, Tierärztlichen Dienst und Labortierkunde, Calwer Straße 7/4, 72076 Tübingen, Tübingen University; permit number: §4 Anzeige 15/10/2009).\n\n"}