PMC:314463 / 688-1042 JSONTXT

{"project":"craft-sa-dev","denotations":[{"id":"T285","span":{"begin":0,"end":8},"obj":"VBP"},{"id":"T286","span":{"begin":9,"end":10},"obj":"DT"},{"id":"T287","span":{"begin":18,"end":26},"obj":"NN"},{"id":"T288","span":{"begin":11,"end":14},"obj":"CD"},{"id":"T289","span":{"begin":15,"end":17},"obj":"NN"},{"id":"T290","span":{"begin":27,"end":29},"obj":"IN"},{"id":"T291","span":{"begin":30,"end":33},"obj":"NN"},{"id":"T292","span":{"begin":34,"end":38},"obj":"WDT"},{"id":"T293","span":{"begin":39,"end":46},"obj":"VBZ"},{"id":"T294","span":{"begin":47,"end":50},"obj":"DT"},{"id":"T295","span":{"begin":51,"end":54},"obj":"IN"},{"id":"T296","span":{"begin":55,"end":58},"obj":"DT"},{"id":"T297","span":{"begin":65,"end":69},"obj":"NN"},{"id":"T298","span":{"begin":59,"end":64},"obj":"JJ"},{"id":"T299","span":{"begin":70,"end":72},"obj":"IN"},{"id":"T300","span":{"begin":73,"end":76},"obj":"DT"},{"id":"T301","span":{"begin":83,"end":87},"obj":"NN"},{"id":"T302","span":{"begin":77,"end":82},"obj":"NN"},{"id":"T303","span":{"begin":87,"end":89},"obj":","},{"id":"T304","span":{"begin":89,"end":94},"obj":"WP$"},{"id":"T305","span":{"begin":105,"end":115},"obj":"NN"},{"id":"T306","span":{"begin":95,"end":104},"obj":"JJ"},{"id":"T307","span":{"begin":141,"end":151},"obj":"VBZ"},{"id":"T308","span":{"begin":116,"end":118},"obj":"IN"},{"id":"T309","span":{"begin":119,"end":129},"obj":"VBG"},{"id":"T310","span":{"begin":130,"end":140},"obj":"NN"},{"id":"T311","span":{"begin":152,"end":156},"obj":"IN"},{"id":"T312","span":{"begin":157,"end":167},"obj":"JJ"},{"id":"T313","span":{"begin":181,"end":194},"obj":"NNS"},{"id":"T314","span":{"begin":168,"end":171},"obj":"CC"},{"id":"T315","span":{"begin":172,"end":180},"obj":"JJ"},{"id":"T316","span":{"begin":195,"end":203},"obj":"VBN"},{"id":"T317","span":{"begin":204,"end":206},"obj":"IN"},{"id":"T318","span":{"begin":207,"end":210},"obj":"NN"},{"id":"T319","span":{"begin":211,"end":214},"obj":"NN"},{"id":"T320","span":{"begin":210,"end":211},"obj":"HYPH"},{"id":"T321","span":{"begin":215,"end":222},"obj":"NNS"},{"id":"T322","span":{"begin":222,"end":223},"obj":"."},{"id":"T323","span":{"begin":223,"end":337},"obj":"sentence"},{"id":"T324","span":{"begin":224,"end":236},"obj":"NN"},{"id":"T325","span":{"begin":267,"end":276},"obj":"VBD"},{"id":"T326","span":{"begin":237,"end":239},"obj":"IN"},{"id":"T327","span":{"begin":240,"end":241},"obj":"DT"},{"id":"T328","span":{"begin":251,"end":257},"obj":"NN"},{"id":"T329","span":{"begin":242,"end":250},"obj":"VBN"},{"id":"T330","span":{"begin":258,"end":260},"obj":"IN"},{"id":"T331","span":{"begin":261,"end":266},"obj":"NN"},{"id":"T332","span":{"begin":277,"end":281},"obj":"IN"},{"id":"T333","span":{"begin":304,"end":310},"obj":"VBN"},{"id":"T334","span":{"begin":282,"end":285},"obj":"DT"},{"id":"T335","span":{"begin":290,"end":299},"obj":"NN"},{"id":"T336","span":{"begin":286,"end":289},"obj":"NN"},{"id":"T337","span":{"begin":300,"end":303},"obj":"VBD"},{"id":"T338","span":{"begin":311,"end":313},"obj":"IN"},{"id":"T339","span":{"begin":314,"end":319},"obj":"NN"},{"id":"T340","span":{"begin":320,"end":324},"obj":"NN"},{"id":"T341","span":{"begin":325,"end":327},"obj":"IN"},{"id":"T342","span":{"begin":328,"end":336},"obj":"NN"},{"id":"T343","span":{"begin":336,"end":337},"obj":"."},{"id":"T345","span":{"begin":338,"end":343},"obj":"RB"},{"id":"T346","span":{"begin":344,"end":353},"obj":"JJ"}],"relations":[{"id":"R107","pred":"det","subj":"T286","obj":"T287"},{"id":"R108","pred":"dobj","subj":"T287","obj":"T285"},{"id":"R111","pred":"prep","subj":"T290","obj":"T287"},{"id":"R112","pred":"pobj","subj":"T291","obj":"T290"},{"id":"R113","pred":"dep","subj":"T292","obj":"T293"},{"id":"R114","pred":"relcl","subj":"T293","obj":"T287"},{"id":"R115","pred":"dobj","subj":"T294","obj":"T293"},{"id":"R116","pred":"prep","subj":"T295","obj":"T294"},{"id":"R117","pred":"det","subj":"T296","obj":"T297"},{"id":"R118","pred":"pobj","subj":"T297","obj":"T295"},{"id":"R120","pred":"prep","subj":"T299","obj":"T297"},{"id":"R121","pred":"det","subj":"T300","obj":"T301"},{"id":"R122","pred":"pobj","subj":"T301","obj":"T299"},{"id":"R124","pred":"punct","subj":"T303","obj":"T297"},{"id":"R125","pred":"poss","subj":"T304","obj":"T305"},{"id":"R126","pred":"dep","subj":"T305","obj":"T307"},{"id":"R128","pred":"relcl","subj":"T307","obj":"T297"},{"id":"R132","pred":"prep","subj":"T311","obj":"T307"},{"id":"R133","pred":"amod","subj":"T312","obj":"T313"},{"id":"R134","pred":"pobj","subj":"T313","obj":"T311"},{"id":"R137","pred":"acl","subj":"T316","obj":"T313"},{"id":"R138","pred":"prep","subj":"T317","obj":"T316"},{"id":"R139","pred":"compound","subj":"T318","obj":"T319"},{"id":"R140","pred":"compound","subj":"T319","obj":"T321"},{"id":"R142","pred":"pobj","subj":"T321","obj":"T317"},{"id":"R143","pred":"punct","subj":"T322","obj":"T285"},{"id":"R144","pred":"nsubj","subj":"T324","obj":"T325"},{"id":"R145","pred":"prep","subj":"T326","obj":"T324"},{"id":"R146","pred":"det","subj":"T327","obj":"T328"},{"id":"R147","pred":"pobj","subj":"T328","obj":"T326"},{"id":"R149","pred":"prep","subj":"T330","obj":"T328"},{"id":"R150","pred":"pobj","subj":"T331","obj":"T330"},{"id":"R151","pred":"mark","subj":"T332","obj":"T333"},{"id":"R152","pred":"ccomp","subj":"T333","obj":"T325"},{"id":"R154","pred":"nsubjpass","subj":"T335","obj":"T333"},{"id":"R155","pred":"compound","subj":"T336","obj":"T335"},{"id":"R157","pred":"agent","subj":"T338","obj":"T333"},{"id":"R158","pred":"compound","subj":"T339","obj":"T340"},{"id":"R159","pred":"pobj","subj":"T340","obj":"T338"},{"id":"R160","pred":"prep","subj":"T341","obj":"T340"},{"id":"R161","pred":"pobj","subj":"T342","obj":"T341"},{"id":"R162","pred":"punct","subj":"T343","obj":"T325"},{"id":"R163","pred":"advmod","subj":"T345","obj":"T346"},{"id":"R109","pred":"nummod","subj":"T288","obj":"T289"},{"id":"R110","pred":"compound","subj":"T289","obj":"T287"},{"id":"R119","pred":"amod","subj":"T298","obj":"T297"},{"id":"R123","pred":"compound","subj":"T302","obj":"T301"},{"id":"R127","pred":"amod","subj":"T306","obj":"T305"},{"id":"R129","pred":"prep","subj":"T308","obj":"T305"},{"id":"R130","pred":"amod","subj":"T309","obj":"T310"},{"id":"R131","pred":"pobj","subj":"T310","obj":"T308"},{"id":"R135","pred":"cc","subj":"T314","obj":"T312"},{"id":"R136","pred":"conj","subj":"T315","obj":"T312"},{"id":"R141","pred":"punct","subj":"T320","obj":"T319"},{"id":"R148","pred":"amod","subj":"T329","obj":"T328"},{"id":"R153","pred":"det","subj":"T334","obj":"T335"},{"id":"R156","pred":"auxpass","subj":"T337","obj":"T333"}],"text":"identify a 216 kb deletion in deH that removes all but the first exon of the Tbx15 gene, whose embryonic expression in developing mesenchyme correlates with pigmentary and skeletal malformations observed in deH/deH animals. Construction of a targeted allele of Tbx15 confirmed that the deH phenotype was caused by Tbx15 loss of function. Early embryonic "}

{"project":"craft-ca-core-dev","denotations":[{"id":"T60","span":{"begin":65,"end":69},"obj":"SO:0000147"},{"id":"T61","span":{"begin":77,"end":82},"obj":"PR:000016145"},{"id":"T62","span":{"begin":83,"end":87},"obj":"SO:0000704"},{"id":"T63","span":{"begin":95,"end":104},"obj":"UBERON:0000922"},{"id":"T64","span":{"begin":105,"end":115},"obj":"GO:0010467"},{"id":"T65","span":{"begin":130,"end":140},"obj":"UBERON:0003104"},{"id":"T66","span":{"begin":157,"end":167},"obj":"CHEBI:26130"},{"id":"T67","span":{"begin":172,"end":180},"obj":"UBERON:0004288"},{"id":"T68","span":{"begin":215,"end":222},"obj":"NCBITaxon:33208"},{"id":"T69","span":{"begin":251,"end":257},"obj":"SO:0001023"},{"id":"T70","span":{"begin":261,"end":266},"obj":"PR:000016145"},{"id":"T71","span":{"begin":314,"end":319},"obj":"PR:000016145"},{"id":"T72","span":{"begin":344,"end":353},"obj":"UBERON:0000922"}],"text":"identify a 216 kb deletion in deH that removes all but the first exon of the Tbx15 gene, whose embryonic expression in developing mesenchyme correlates with pigmentary and skeletal malformations observed in deH/deH animals. Construction of a targeted allele of Tbx15 confirmed that the deH phenotype was caused by Tbx15 loss of function. Early embryonic "}

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T122","span":{"begin":16,"end":17},"obj":"CHEBI_SO_EXT:base"},{"id":"T123","span":{"begin":18,"end":26},"obj":"SO_EXT:sequence_deletion_entity_or_process"},{"id":"T125","span":{"begin":77,"end":82},"obj":"PR_EXT:000016145"},{"id":"T126","span":{"begin":83,"end":87},"obj":"SO_EXT:0000704"},{"id":"T127","span":{"begin":95,"end":104},"obj":"UBERON:0000922"},{"id":"T128","span":{"begin":105,"end":115},"obj":"GO:0010467"},{"id":"T129","span":{"begin":130,"end":140},"obj":"UBERON:0003104"},{"id":"T130","span":{"begin":157,"end":167},"obj":"CHEBI_EXT:26130"},{"id":"T131","span":{"begin":172,"end":180},"obj":"UBERON:0004288"},{"id":"T132","span":{"begin":215,"end":222},"obj":"NCBITaxon:33208"},{"id":"T133","span":{"begin":251,"end":257},"obj":"SO_EXT:0001023"},{"id":"T134","span":{"begin":261,"end":266},"obj":"PR_EXT:000016145"},{"id":"T135","span":{"begin":314,"end":319},"obj":"PR_EXT:000016145"},{"id":"T136","span":{"begin":344,"end":353},"obj":"UBERON:0000922"},{"id":"T124","span":{"begin":65,"end":69},"obj":"SO_EXT:0000147"}],"text":"identify a 216 kb deletion in deH that removes all but the first exon of the Tbx15 gene, whose embryonic expression in developing mesenchyme correlates with pigmentary and skeletal malformations observed in deH/deH animals. Construction of a targeted allele of Tbx15 confirmed that the deH phenotype was caused by Tbx15 loss of function. Early embryonic "}