PMC:314463 / 26567-27143 JSONTXT

{"project":"craft-sa-dev","denotations":[{"id":"T5731","span":{"begin":0,"end":8},"obj":"IN"},{"id":"T5732","span":{"begin":57,"end":62},"obj":"VBP"},{"id":"T5733","span":{"begin":9,"end":12},"obj":"DT"},{"id":"T5734","span":{"begin":13,"end":20},"obj":"NNS"},{"id":"T5735","span":{"begin":21,"end":23},"obj":"IN"},{"id":"T5736","span":{"begin":24,"end":30},"obj":"NN"},{"id":"T5737","span":{"begin":31,"end":33},"obj":"IN"},{"id":"T5738","span":{"begin":34,"end":41},"obj":"NN"},{"id":"T5739","span":{"begin":42,"end":46},"obj":"NN"},{"id":"T5740","span":{"begin":41,"end":42},"obj":"HYPH"},{"id":"T5741","span":{"begin":47,"end":56},"obj":"VBG"},{"id":"T5742","span":{"begin":135,"end":144},"obj":"VBN"},{"id":"T5743","span":{"begin":63,"end":69},"obj":"IN"},{"id":"T5744","span":{"begin":70,"end":79},"obj":"JJ"},{"id":"T5745","span":{"begin":85,"end":91},"obj":"NN"},{"id":"T5746","span":{"begin":80,"end":84},"obj":"NN"},{"id":"T5747","span":{"begin":91,"end":93},"obj":","},{"id":"T5748","span":{"begin":93,"end":96},"obj":"DT"},{"id":"T5749","span":{"begin":114,"end":121},"obj":"NN"},{"id":"T5750","span":{"begin":97,"end":104},"obj":"JJ"},{"id":"T5751","span":{"begin":105,"end":113},"obj":"JJ"},{"id":"T5752","span":{"begin":104,"end":105},"obj":"HYPH"},{"id":"T5753","span":{"begin":122,"end":124},"obj":"IN"},{"id":"T5754","span":{"begin":125,"end":131},"obj":"NN"},{"id":"T5755","span":{"begin":132,"end":134},"obj":"VBZ"},{"id":"T5756","span":{"begin":145,"end":147},"obj":"IN"},{"id":"T5757","span":{"begin":148,"end":158},"obj":"VBG"},{"id":"T5758","span":{"begin":159,"end":163},"obj":"NN"},{"id":"T5759","span":{"begin":164,"end":173},"obj":"VBG"},{"id":"T5760","span":{"begin":174,"end":176},"obj":"IN"},{"id":"T5761","span":{"begin":177,"end":182},"obj":"NN"},{"id":"T5762","span":{"begin":182,"end":183},"obj":"."},{"id":"T5763","span":{"begin":183,"end":404},"obj":"sentence"},{"id":"T5764","span":{"begin":184,"end":186},"obj":"PRP"},{"id":"T5765","span":{"begin":187,"end":195},"obj":"VBD"},{"id":"T5766","span":{"begin":196,"end":204},"obj":"JJ"},{"id":"T5767","span":{"begin":205,"end":213},"obj":"NNS"},{"id":"T5768","span":{"begin":214,"end":224},"obj":"VBN"},{"id":"T5769","span":{"begin":225,"end":229},"obj":"IN"},{"id":"T5770","span":{"begin":230,"end":236},"obj":"NNS"},{"id":"T5771","span":{"begin":237,"end":240},"obj":"IN"},{"id":"T5772","span":{"begin":241,"end":246},"obj":"NN"},{"id":"T5773","span":{"begin":247,"end":250},"obj":"CC"},{"id":"T5774","span":{"begin":251,"end":257},"obj":"NN"},{"id":"T5775","span":{"begin":258,"end":261},"obj":"CC"},{"id":"T5776","span":{"begin":262,"end":270},"obj":"VBD"},{"id":"T5777","span":{"begin":271,"end":284},"obj":"JJ"},{"id":"T5778","span":{"begin":285,"end":293},"obj":"NNS"},{"id":"T5779","span":{"begin":294,"end":296},"obj":"IN"},{"id":"T5780","span":{"begin":297,"end":302},"obj":"NN"},{"id":"T5781","span":{"begin":302,"end":304},"obj":","},{"id":"T5782","span":{"begin":304,"end":308},"obj":"IN"},{"id":"T5783","span":{"begin":309,"end":319},"obj":"NN"},{"id":"T5784","span":{"begin":320,"end":322},"obj":"IN"},{"id":"T5785","span":{"begin":323,"end":329},"obj":"NN"},{"id":"T5786","span":{"begin":330,"end":332},"obj":"IN"},{"id":"T5787","span":{"begin":333,"end":340},"obj":"JJ"},{"id":"T5788","span":{"begin":341,"end":345},"obj":"NN"},{"id":"T5789","span":{"begin":346,"end":349},"obj":"CC"},{"id":"T5790","span":{"begin":350,"end":360},"obj":"NN"},{"id":"T5791","span":{"begin":361,"end":363},"obj":"IN"},{"id":"T5792","span":{"begin":364,"end":369},"obj":"NN"},{"id":"T5793","span":{"begin":370,"end":372},"obj":"IN"},{"id":"T5794","span":{"begin":373,"end":379},"obj":"JJ"},{"id":"T5795","span":{"begin":380,"end":384},"obj":"NN"},{"id":"T5796","span":{"begin":385,"end":386},"obj":"-LRB-"},{"id":"T5797","span":{"begin":393,"end":395},"obj":"CD"},{"id":"T5798","span":{"begin":386,"end":392},"obj":"NN"},{"id":"T5799","span":{"begin":396,"end":399},"obj":"CC"},{"id":"T5800","span":{"begin":400,"end":402},"obj":"CD"},{"id":"T5801","span":{"begin":402,"end":403},"obj":"-RRB-"},{"id":"T5802","span":{"begin":403,"end":404},"obj":"."},{"id":"T5803","span":{"begin":404,"end":576},"obj":"sentence"},{"id":"T5804","span":{"begin":405,"end":408},"obj":"DT"},{"id":"T5805","span":{"begin":409,"end":417},"obj":"NN"},{"id":"T5806","span":{"begin":445,"end":447},"obj":"VBZ"},{"id":"T5807","span":{"begin":418,"end":425},"obj":"IN"},{"id":"T5808","span":{"begin":426,"end":436},"obj":"NN"},{"id":"T5809","span":{"begin":437,"end":444},"obj":"NNS"},{"id":"T5810","span":{"begin":448,"end":458},"obj":"JJ"},{"id":"T5811","span":{"begin":458,"end":460},"obj":","},{"id":"T5812","span":{"begin":460,"end":463},"obj":"CC"},{"id":"T5813","span":{"begin":464,"end":466},"obj":"IN"},{"id":"T5814","span":{"begin":491,"end":498},"obj":"VBZ"},{"id":"T5815","span":{"begin":467,"end":472},"obj":"NN"},{"id":"T5816","span":{"begin":472,"end":474},"obj":","},{"id":"T5817","span":{"begin":474,"end":479},"obj":"NN"},{"id":"T5818","span":{"begin":480,"end":490},"obj":"NN"},{"id":"T5819","span":{"begin":499,"end":508},"obj":"RB"},{"id":"T5820","span":{"begin":509,"end":512},"obj":"CC"},{"id":"T5821","span":{"begin":513,"end":521},"obj":"VBZ"},{"id":"T5822","span":{"begin":522,"end":533},"obj":"RB"},{"id":"T5823","span":{"begin":534,"end":538},"obj":"IN"},{"id":"T5824","span":{"begin":539,"end":545},"obj":"NN"},{"id":"T5825","span":{"begin":546,"end":556},"obj":"NN"},{"id":"T5826","span":{"begin":557,"end":558},"obj":"-LRB-"},{"id":"T5827","span":{"begin":565,"end":567},"obj":"CD"},{"id":"T5828","span":{"begin":558,"end":564},"obj":"NN"},{"id":"T5829","span":{"begin":568,"end":571},"obj":"CC"},{"id":"T5830","span":{"begin":572,"end":574},"obj":"CD"},{"id":"T5831","span":{"begin":574,"end":575},"obj":"-RRB-"},{"id":"T5832","span":{"begin":575,"end":576},"obj":"."}],"relations":[{"id":"R3918","pred":"mark","subj":"T5731","obj":"T5732"},{"id":"R3919","pred":"advcl","subj":"T5732","obj":"T5742"},{"id":"R3920","pred":"det","subj":"T5733","obj":"T5734"},{"id":"R3921","pred":"nsubj","subj":"T5734","obj":"T5732"},{"id":"R3922","pred":"prep","subj":"T5735","obj":"T5734"},{"id":"R3923","pred":"pobj","subj":"T5736","obj":"T5735"},{"id":"R3924","pred":"prep","subj":"T5737","obj":"T5734"},{"id":"R3925","pred":"compound","subj":"T5738","obj":"T5739"},{"id":"R3926","pred":"pobj","subj":"T5739","obj":"T5737"},{"id":"R3927","pred":"punct","subj":"T5740","obj":"T5739"},{"id":"R3928","pred":"amod","subj":"T5741","obj":"T5739"},{"id":"R3929","pred":"prep","subj":"T5743","obj":"T5732"},{"id":"R3930","pred":"amod","subj":"T5744","obj":"T5745"},{"id":"R3931","pred":"pobj","subj":"T5745","obj":"T5743"},{"id":"R3932","pred":"compound","subj":"T5746","obj":"T5745"},{"id":"R3933","pred":"punct","subj":"T5747","obj":"T5742"},{"id":"R3934","pred":"det","subj":"T5748","obj":"T5749"},{"id":"R3935","pred":"nsubjpass","subj":"T5749","obj":"T5742"},{"id":"R3936","pred":"amod","subj":"T5750","obj":"T5751"},{"id":"R3937","pred":"amod","subj":"T5751","obj":"T5749"},{"id":"R3938","pred":"punct","subj":"T5752","obj":"T5751"},{"id":"R3939","pred":"prep","subj":"T5753","obj":"T5749"},{"id":"R3940","pred":"pobj","subj":"T5754","obj":"T5753"},{"id":"R3941","pred":"auxpass","subj":"T5755","obj":"T5742"},{"id":"R3942","pred":"prep","subj":"T5756","obj":"T5742"},{"id":"R3943","pred":"amod","subj":"T5757","obj":"T5758"},{"id":"R3944","pred":"pobj","subj":"T5758","obj":"T5756"},{"id":"R3945","pred":"advcl","subj":"T5759","obj":"T5742"},{"id":"R3946","pred":"prep","subj":"T5760","obj":"T5759"},{"id":"R3947","pred":"pobj","subj":"T5761","obj":"T5760"},{"id":"R3948","pred":"punct","subj":"T5762","obj":"T5742"},{"id":"R3949","pred":"nsubj","subj":"T5764","obj":"T5765"},{"id":"R3950","pred":"amod","subj":"T5766","obj":"T5767"},{"id":"R3951","pred":"dobj","subj":"T5767","obj":"T5765"},{"id":"R3952","pred":"acl","subj":"T5768","obj":"T5767"},{"id":"R3953","pred":"prep","subj":"T5769","obj":"T5768"},{"id":"R3954","pred":"pobj","subj":"T5770","obj":"T5769"},{"id":"R3955","pred":"prep","subj":"T5771","obj":"T5770"},{"id":"R3956","pred":"pobj","subj":"T5772","obj":"T5771"},{"id":"R3957","pred":"cc","subj":"T5773","obj":"T5772"},{"id":"R3958","pred":"conj","subj":"T5774","obj":"T5772"},{"id":"R3959","pred":"cc","subj":"T5775","obj":"T5776"},{"id":"R3960","pred":"dep","subj":"T5776","obj":"T5765"},{"id":"R3961","pred":"amod","subj":"T5777","obj":"T5778"},{"id":"R3962","pred":"dobj","subj":"T5778","obj":"T5776"},{"id":"R3963","pred":"prep","subj":"T5779","obj":"T5776"},{"id":"R3964","pred":"pobj","subj":"T5780","obj":"T5779"},{"id":"R3965","pred":"punct","subj":"T5781","obj":"T5776"},{"id":"R3966","pred":"mark","subj":"T5782","obj":"T5783"},{"id":"R3967","pred":"advcl","subj":"T5783","obj":"T5776"},{"id":"R3968","pred":"prep","subj":"T5784","obj":"T5783"},{"id":"R3969","pred":"pobj","subj":"T5785","obj":"T5784"},{"id":"R3970","pred":"prep","subj":"T5786","obj":"T5783"},{"id":"R3971","pred":"amod","subj":"T5787","obj":"T5788"},{"id":"R3972","pred":"pobj","subj":"T5788","obj":"T5786"},{"id":"R3973","pred":"cc","subj":"T5789","obj":"T5783"},{"id":"R3974","pred":"conj","subj":"T5790","obj":"T5783"},{"id":"R3975","pred":"prep","subj":"T5791","obj":"T5790"},{"id":"R3976","pred":"pobj","subj":"T5792","obj":"T5791"},{"id":"R3977","pred":"prep","subj":"T5793","obj":"T5790"},{"id":"R3978","pred":"amod","subj":"T5794","obj":"T5795"},{"id":"R3979","pred":"pobj","subj":"T5795","obj":"T5793"},{"id":"R3980","pred":"punct","subj":"T5796","obj":"T5797"},{"id":"R3981","pred":"parataxis","subj":"T5797","obj":"T5776"},{"id":"R3982","pred":"nmod","subj":"T5798","obj":"T5797"},{"id":"R3983","pred":"cc","subj":"T5799","obj":"T5797"},{"id":"R3984","pred":"conj","subj":"T5800","obj":"T5797"},{"id":"R3985","pred":"punct","subj":"T5801","obj":"T5797"},{"id":"R3986","pred":"punct","subj":"T5802","obj":"T5765"},{"id":"R3987","pred":"det","subj":"T5804","obj":"T5805"},{"id":"R3988","pred":"nsubj","subj":"T5805","obj":"T5806"},{"id":"R3989","pred":"prep","subj":"T5807","obj":"T5805"},{"id":"R3990","pred":"compound","subj":"T5808","obj":"T5809"},{"id":"R3991","pred":"pobj","subj":"T5809","obj":"T5807"},{"id":"R3992","pred":"acomp","subj":"T5810","obj":"T5806"},{"id":"R3993","pred":"punct","subj":"T5811","obj":"T5806"},{"id":"R3994","pred":"cc","subj":"T5812","obj":"T5806"},{"id":"R3995","pred":"prep","subj":"T5813","obj":"T5814"},{"id":"R3996","pred":"conj","subj":"T5814","obj":"T5806"},{"id":"R3997","pred":"pobj","subj":"T5815","obj":"T5813"},{"id":"R3998","pred":"punct","subj":"T5816","obj":"T5814"},{"id":"R3999","pred":"compound","subj":"T5817","obj":"T5818"},{"id":"R4000","pred":"nsubj","subj":"T5818","obj":"T5814"},{"id":"R4001","pred":"advmod","subj":"T5819","obj":"T5814"},{"id":"R4002","pred":"cc","subj":"T5820","obj":"T5814"},{"id":"R4003","pred":"conj","subj":"T5821","obj":"T5814"},{"id":"R4004","pred":"advmod","subj":"T5822","obj":"T5821"},{"id":"R4005","pred":"prep","subj":"T5823","obj":"T5821"},{"id":"R4006","pred":"compound","subj":"T5824","obj":"T5825"},{"id":"R4007","pred":"pobj","subj":"T5825","obj":"T5823"},{"id":"R4008","pred":"punct","subj":"T5826","obj":"T5827"},{"id":"R4009","pred":"parataxis","subj":"T5827","obj":"T5821"},{"id":"R4010","pred":"nmod","subj":"T5828","obj":"T5827"},{"id":"R4011","pred":"cc","subj":"T5829","obj":"T5827"},{"id":"R4012","pred":"conj","subj":"T5830","obj":"T5827"},{"id":"R4013","pred":"punct","subj":"T5831","obj":"T5827"},{"id":"R4014","pred":"punct","subj":"T5832","obj":"T5814"}],"text":"Although the effects of Agouti on pigment-type switching occur during postnatal hair growth, the ventral-specific isoform of Agouti is expressed in developing skin beginning at E11.5. We compared adjacent sections hybridized with probes for Tbx15 and Agouti and observed complementary patterns at E12.5, with expression of Agouti in ventral skin and expression of Tbx15 in dorsal skin (Figure 5A and 5B). The junction between expression domains is indistinct, and by E14.5, Tbx15 expression extends ventrally and overlaps extensively with Agouti expression (Figure 5C and 5D)."}

{"project":"craft-ca-core-dev","denotations":[{"id":"T5323","span":{"begin":24,"end":30},"obj":"PR:000004372"},{"id":"T5324","span":{"begin":34,"end":41},"obj":"CHEBI:26130"},{"id":"T5325","span":{"begin":74,"end":79},"obj":"GO:0007567"},{"id":"T5326","span":{"begin":80,"end":84},"obj":"UBERON:0001037"},{"id":"T5327","span":{"begin":114,"end":121},"obj":"SO:0001060"},{"id":"T5328","span":{"begin":125,"end":131},"obj":"PR:000004372"},{"id":"T5329","span":{"begin":135,"end":144},"obj":"GO:0010467"},{"id":"T5330","span":{"begin":214,"end":224},"obj":"GO:0097617"},{"id":"T5331","span":{"begin":241,"end":246},"obj":"PR:000016145"},{"id":"T5332","span":{"begin":251,"end":257},"obj":"PR:000004372"},{"id":"T5333","span":{"begin":309,"end":319},"obj":"GO:0010467"},{"id":"T5334","span":{"begin":323,"end":329},"obj":"PR:000004372"},{"id":"T5335","span":{"begin":350,"end":360},"obj":"GO:0010467"},{"id":"T5336","span":{"begin":364,"end":369},"obj":"PR:000016145"},{"id":"T5337","span":{"begin":426,"end":436},"obj":"GO:0010467"},{"id":"T5338","span":{"begin":474,"end":479},"obj":"PR:000016145"},{"id":"T5339","span":{"begin":480,"end":490},"obj":"GO:0010467"},{"id":"T5340","span":{"begin":539,"end":545},"obj":"PR:000004372"},{"id":"T5341","span":{"begin":546,"end":556},"obj":"GO:0010467"}],"text":"Although the effects of Agouti on pigment-type switching occur during postnatal hair growth, the ventral-specific isoform of Agouti is expressed in developing skin beginning at E11.5. We compared adjacent sections hybridized with probes for Tbx15 and Agouti and observed complementary patterns at E12.5, with expression of Agouti in ventral skin and expression of Tbx15 in dorsal skin (Figure 5A and 5B). The junction between expression domains is indistinct, and by E14.5, Tbx15 expression extends ventrally and overlaps extensively with Agouti expression (Figure 5C and 5D)."}

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T5414","span":{"begin":24,"end":30},"obj":"PR_EXT:000004372"},{"id":"T5415","span":{"begin":34,"end":41},"obj":"CHEBI_EXT:26130"},{"id":"T5416","span":{"begin":74,"end":79},"obj":"GO:0007567"},{"id":"T5417","span":{"begin":80,"end":84},"obj":"UBERON:0001037"},{"id":"T5418","span":{"begin":85,"end":91},"obj":"GO_EXT:biological_growth_entity_or_process"},{"id":"T5419","span":{"begin":114,"end":121},"obj":"SO_EXT:0001060"},{"id":"T5420","span":{"begin":125,"end":131},"obj":"PR_EXT:000004372"},{"id":"T5421","span":{"begin":135,"end":144},"obj":"GO:0010467"},{"id":"T5422","span":{"begin":159,"end":163},"obj":"UBERON_EXT:zone_of_skin_or_skin_of_body"},{"id":"T5423","span":{"begin":214,"end":224},"obj":"GO:0097617"},{"id":"T5424","span":{"begin":230,"end":236},"obj":"CHEBI_SO_EXT:molecular_probe"},{"id":"T5425","span":{"begin":241,"end":246},"obj":"PR_EXT:000016145"},{"id":"T5426","span":{"begin":251,"end":257},"obj":"PR_EXT:000004372"},{"id":"T5427","span":{"begin":309,"end":319},"obj":"GO:0010467"},{"id":"T5428","span":{"begin":323,"end":329},"obj":"PR_EXT:000004372"},{"id":"T5429","span":{"begin":341,"end":345},"obj":"UBERON_EXT:zone_of_skin_or_skin_of_body"},{"id":"T5430","span":{"begin":350,"end":360},"obj":"GO:0010467"},{"id":"T5431","span":{"begin":364,"end":369},"obj":"PR_EXT:000016145"},{"id":"T5432","span":{"begin":380,"end":384},"obj":"UBERON_EXT:zone_of_skin_or_skin_of_body"},{"id":"T5433","span":{"begin":426,"end":436},"obj":"GO:0010467"},{"id":"T5434","span":{"begin":474,"end":479},"obj":"PR_EXT:000016145"},{"id":"T5435","span":{"begin":480,"end":490},"obj":"GO:0010467"},{"id":"T5436","span":{"begin":539,"end":545},"obj":"PR_EXT:000004372"},{"id":"T5437","span":{"begin":546,"end":556},"obj":"GO:0010467"}],"text":"Although the effects of Agouti on pigment-type switching occur during postnatal hair growth, the ventral-specific isoform of Agouti is expressed in developing skin beginning at E11.5. We compared adjacent sections hybridized with probes for Tbx15 and Agouti and observed complementary patterns at E12.5, with expression of Agouti in ventral skin and expression of Tbx15 in dorsal skin (Figure 5A and 5B). The junction between expression domains is indistinct, and by E14.5, Tbx15 expression extends ventrally and overlaps extensively with Agouti expression (Figure 5C and 5D)."}