PMC:3091642 / 31509-32286 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/3091642","sourcedb":"PMC","sourceid":"3091642","source_url":"https://www.ncbi.nlm.nih.gov/pmc/3091642","text":"In this study, we have demonstrated changes in global gene expression in response to ILTV infection in chicken embryo lung cells using microarray analysis. A total of 789 differentially expressed genes were involved in a variety of molecular and cellular defense mechanisms of immune response, cell cycle regulation, cellular metabolism, and matrix metalloprotenases. Moreover, the bioinformatics studies, such as gene ontology and gene network analysis, using knowledge based bioinformatics tools (Ingenuity Pathway Analysis and DAVID) revealed biological functionalities and intermolecular connections among interacting genes associated with differentially expressed genes. Our study provides epigenetic insights into the pathogenesis of ILTV infection in chicken lung cells.","tracks":[]}