PMC:3091640 / 13561-14618 JSONTXT

{"project":"2_test","denotations":[{"id":"20646326-1518831-10480744","span":{"begin":667,"end":669},"obj":"1518831"},{"id":"20646326-9522464-10480745","span":{"begin":670,"end":672},"obj":"9522464"},{"id":"20646326-12768414-10480746","span":{"begin":692,"end":694},"obj":"12768414"},{"id":"20646326-12768414-10480747","span":{"begin":743,"end":745},"obj":"12768414"},{"id":"20646326-20406785-10480748","span":{"begin":746,"end":748},"obj":"20406785"}],"text":"Plants homologs of bacterial DRR gene have very low sequence similarity but retention of conserved domain probably suggested the functional conservation of those proteins. Bacterial homologs were found in all pathways except NHEJ. These prokaryotic and yeast specific genes are not well explored in plant genomes except the bacterial RecA gene. RecA, a gene central to general DNA repair and recombination in bacteria, was found to be most conserved bacterial homolog in plant which showed more than 40% amino acid identity in both genomes in comparison to RecA of E. coli. Arabidopsis encodes orthologs of bacterial RecA proteins which are targeted to chloroplasts [14,15] and mitochondria [16] and reported to be associated with DNA repair [16,17]. Complexes of different proteins plays pivotal role in DNA repair processes. We found that plants appeared to retain a partner of bacterial protein complexes while loose other partners. So, in the absence of partner how these bacterial proteins work would be an important question for further investigation."}