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PMC:3062687 / 9287-12114 JSONTXT

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bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T7633 0-4 O14920 denotes IKKβ
T7634 20-24 P23396 denotes RPS3
T7635 108-112 O14920 denotes IKKβ
T7636 176-181 O95999 denotes Bcl10
T7637 265-269 O14920 denotes IKKβ
T7638 299-303 P23396 denotes RPS3
T7639 357-361 P23396 denotes RPS3
T7640 442-446 O14920 denotes IKKβ
T7641 497-501 P25963 denotes IκBα
T7642 609-613 O14920 denotes IKKβ
T7643 647-651 P23396 denotes RPS3
T7644 679-683 O14920 denotes IKKβ
T7645 758-762 P23396 denotes RPS3
T7646 803-807 O14920 denotes IKKβ
T7647 908-912 P23396 denotes RPS3
T7648 941-945 O14920 denotes IKKβ
T7649 982-986 P23396 denotes RPS3
T7650 1009-1013 P23396 denotes RPS3
T7651 1312-1316 O14920 denotes IKKβ
T7652 1420-1424 P23396 denotes RPS3
T7653 1499-1503 O14920 denotes IKKβ
T7654 1513-1517 P23396 denotes RPS3
T7655 1656-1660 P23396 denotes RPS3
T7656 1672-1676 P23396 denotes RPS3
T7657 1853-1857 O14920 denotes IKKβ
T7658 2011-2015 P23396 denotes RPS3
T7659 2081-2085 O14920 denotes IKKβ
T7660 2200-2204 O14920 denotes IKKβ
T7661 2220-2224 P23396 denotes RPS3
T7662 2292-2296 P23396 denotes RPS3
T7663 2321-2325 O14920 denotes IKKβ
T7664 2378-2382 O14920 denotes IKKβ
T7665 2397-2401 P23396 denotes RPS3
T7666 2546-2550 O14920 denotes IKKβ
T7667 2611-2615 P23396 denotes RPS3
T7668 2655-2659 P23396 denotes RPS3
T7669 2719-2722 P01375 denotes TNF
T7670 2756-2760 P23396 denotes RPS3

2_test

Id Subject Object Predicate Lexical cue
21399639-10837071-74765160 104-106 10837071 denotes 19
21399639-10837071-74765160 104-106 10837071 denotes 19
21399639-16818229-74765161 230-232 16818229 denotes 28
21399639-16818229-74765161 230-232 16818229 denotes 28

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T7159 0-4 NN denotes IKKβ
T7160 5-19 VB denotes phosphorylates
T7161 20-24 NN denotes RPS3
T7162 25-27 IN denotes at
T7163 28-34 NN denotes serine
T7164 35-38 CD denotes 209
T7165 39-47 IN denotes Although
T7166 48-58 RB denotes originally
T7167 59-66 VB denotes defined
T7168 67-69 IN denotes as
T7169 70-73 DT denotes the
T7170 74-80 NN denotes kinase
T7171 81-85 WDT denotes that
T7172 86-100 VB denotes phosphorylates
T7173 101-106 NN denotes IκB19
T7174 106-107 -COMMA- denotes ,
T7175 108-112 NN denotes IKKβ
T7176 113-117 RB denotes also
T7177 118-132 VB denotes phosphorylates
T7178 133-142 JJ denotes unrelated
T7179 143-153 NN denotes substrates
T7180 154-163 VB denotes including
T7181 164-171 JJ denotes 14-3-3β
T7182 172-175 CC denotes and
T7183 176-181 NN denotes Bcl10
T7184 181-182 -COMMA- denotes ,
T7185 183-188 WDT denotes which
T7186 189-193 VB denotes lack
T7187 194-197 DT denotes the
T7188 198-201 NN denotes IKK
T7189 202-211 NN denotes consensus
T7190 212-217 NN denotes motif
T7191 218-219 -LRB- denotes (
T7192 219-229 NN denotes DpSGYXpS/T
T7193 229-230 -RRB- denotes )
T7194 230-232 CD denotes 28
T7195 234-236 PRP denotes We
T7196 237-246 RB denotes therefore
T7197 247-259 VB denotes hypothesized
T7198 260-264 IN denotes that
T7199 265-269 NN denotes IKKβ
T7200 270-275 MD denotes could
T7201 276-284 RB denotes directly
T7202 285-298 VB denotes phosphorylate
T7203 299-303 NN denotes RPS3
T7204 305-307 IN denotes By
T7205 308-310 FW denotes in
T7206 311-316 FW denotes vitro
T7207 317-323 NN denotes kinase
T7208 324-330 NN denotes assays
T7209 331-336 VB denotes using
T7210 337-348 JJ denotes recombinant
T7211 349-352 NN denotes IKK
T7212 353-356 CC denotes and
T7213 357-361 NN denotes RPS3
T7214 362-370 NN denotes proteins
T7215 370-371 -COMMA- denotes ,
T7216 372-374 PRP denotes we
T7217 375-383 VB denotes observed
T7218 384-390 JJ denotes strong
T7219 391-404 NN denotes incorporation
T7220 405-407 IN denotes of
T7221 408-411 NN denotes 32P
T7222 412-414 IN denotes in
T7223 415-432 NN denotes autophosphorylatd
T7224 433-437 NN denotes IKKα
T7225 438-441 CC denotes and
T7226 442-446 NN denotes IKKβ
T7227 447-448 -LRB- denotes (
T7228 448-452 NNP denotes Fig.
T7229 453-455 NN denotes 4a
T7230 455-456 -COMMA- denotes ,
T7231 457-462 NN denotes lanes
T7232 463-466 CD denotes 2-7
T7233 466-467 -RRB- denotes )
T7234 468-470 RB denotes as
T7235 471-475 RB denotes well
T7236 476-478 IN denotes as
T7237 479-492 VB denotes phosporylated
T7238 493-501 NN denotes GST-IκBα
T7239 502-503 -LRB- denotes (
T7240 503-507 CD denotes 1-54
T7241 507-508 -RRB- denotes )
T7242 509-510 -LRB- denotes (
T7243 510-523 NNP denotes Supplementary
T7244 524-528 NNP denotes Fig.
T7245 529-530 CD denotes 4
T7246 530-531 -RRB- denotes )
T7247 531-532 -COMMA- denotes ,
T7248 533-536 CC denotes but
T7249 537-540 RB denotes not
T7250 541-544 DT denotes the
T7251 545-548 NN denotes GST
T7252 549-556 NN denotes protein
T7253 557-562 RB denotes alone
T7254 563-564 -LRB- denotes (
T7255 564-568 NNP denotes Fig.
T7256 569-571 NN denotes 4a
T7257 571-572 -COMMA- denotes ,
T7258 573-578 NN denotes lanes
T7259 579-580 CD denotes 3
T7260 581-584 CC denotes and
T7261 585-586 CD denotes 6
T7262 586-587 -RRB- denotes )
T7263 587-588 -COMMA- denotes ,
T7264 589-593 WRB denotes when
T7265 594-600 CC denotes either
T7266 601-605 NN denotes IKKα
T7267 606-608 CC denotes or
T7268 609-613 NN denotes IKKβ
T7269 614-617 VB denotes was
T7270 618-622 VB denotes used
T7271 624-626 PRP denotes We
T7272 627-637 VB denotes discovered
T7273 638-642 IN denotes that
T7274 643-651 NN denotes GST-RPS3
T7275 652-657 MD denotes could
T7276 658-660 VB denotes be
T7277 661-675 VB denotes phosphorylated
T7278 676-678 IN denotes by
T7279 679-683 NN denotes IKKβ
T7280 683-684 -COMMA- denotes ,
T7281 685-688 CC denotes but
T7282 689-692 RB denotes not
T7283 693-697 NN denotes IKKα
T7284 697-698 -COMMA- denotes ,
T7285 699-701 FW denotes in
T7286 702-707 FW denotes vitro
T7287 708-709 -LRB- denotes (
T7288 709-713 FW denotes Fig.
T7289 714-716 NN denotes 4a
T7290 716-717 -COMMA- denotes ,
T7291 718-725 NN denotes compare
T7292 726-731 NN denotes lanes
T7293 732-733 CD denotes 4
T7294 734-737 CC denotes and
T7295 738-739 CD denotes 7
T7296 739-740 -RRB- denotes )
T7297 742-744 TO denotes To
T7298 745-753 VB denotes identify
T7299 754-757 DT denotes the
T7300 758-762 NN denotes RPS3
T7301 763-768 JJ denotes amino
T7302 769-773 NN denotes acid
T7303 774-781 NN denotes residue
T7304 781-782 -LRB- denotes (
T7305 782-783 NN denotes s
T7306 783-784 -RRB- denotes )
T7307 785-799 VB denotes phosphorylated
T7308 800-802 IN denotes by
T7309 803-807 NN denotes IKKβ
T7310 807-808 -COMMA- denotes ,
T7311 809-811 PRP denotes we
T7312 812-821 VB denotes performed
T7313 822-828 JJ denotes liquid
T7314 829-850 JJ denotes chromatography-tandem
T7315 851-855 NN denotes mass
T7316 856-868 NN denotes spectrometry
T7317 869-877 NN denotes analyses
T7318 878-883 VB denotes using
T7319 884-886 FW denotes in
T7320 887-892 FW denotes vitro
T7321 893-907 VB denotes phosphorylated
T7322 908-912 NN denotes RPS3
T7323 914-917 DT denotes The
T7324 918-925 NN denotes results
T7325 926-935 VB denotes indicated
T7326 936-940 IN denotes that
T7327 941-945 NN denotes IKKβ
T7328 946-960 VB denotes phosphorylated
T7329 961-965 NN denotes S209
T7330 965-966 -COMMA- denotes ,
T7331 967-974 JJ denotes located
T7332 975-977 IN denotes in
T7333 978-981 DT denotes the
T7334 982-986 NN denotes RPS3
T7335 987-997 NN denotes C-terminus
T7336 998-999 -LRB- denotes (
T7337 999-1003 NN denotes Fig.
T7338 1004-1006 NN denotes 4b
T7339 1006-1007 -RRB- denotes )
T7340 1009-1013 NN denotes RPS3
T7341 1014-1019 JJ denotes amino
T7342 1020-1024 NN denotes acid
T7343 1025-1033 NN denotes sequence
T7344 1034-1043 NN denotes alignment
T7345 1044-1052 VB denotes revealed
T7346 1053-1057 IN denotes that
T7347 1058-1062 NN denotes S209
T7348 1063-1065 VB denotes is
T7349 1066-1075 VB denotes conserved
T7350 1076-1078 IN denotes in
T7351 1079-1083 JJ denotes many
T7352 1084-1091 NN denotes species
T7353 1092-1102 IN denotes throughout
T7354 1103-1112 NN denotes phylogeny
T7355 1113-1117 IN denotes with
T7356 1118-1121 DT denotes the
T7357 1122-1131 NN denotes exception
T7358 1132-1134 IN denotes of
T7359 1135-1149 NN denotes Caenorhabditis
T7360 1150-1157 NN denotes elegans
T7361 1158-1161 CC denotes and
T7362 1162-1181 FW denotes Schizosaccharomyces
T7363 1182-1187 FW denotes pombe
T7364 1187-1188 -COMMA- denotes ,
T7365 1189-1192 CD denotes two
T7366 1193-1202 NN denotes organisms
T7367 1203-1207 WDT denotes that
T7368 1208-1210 VB denotes do
T7369 1211-1214 RB denotes not
T7370 1215-1222 VB denotes possess
T7371 1223-1226 DT denotes the
T7372 1227-1232 NN denotes NF-κB
T7373 1233-1239 NN denotes signal
T7374 1240-1247 NN denotes pathway
T7375 1248-1249 -LRB- denotes (
T7376 1249-1262 NNP denotes Supplementary
T7377 1263-1267 NNP denotes Fig.
T7378 1268-1269 CD denotes 5
T7379 1269-1270 -RRB- denotes )
T7380 1272-1274 TO denotes To
T7381 1275-1281 VB denotes verify
T7382 1282-1295 RB denotes biochemically
T7383 1296-1300 IN denotes that
T7384 1301-1305 NN denotes S209
T7385 1306-1308 VB denotes is
T7386 1309-1311 DT denotes an
T7387 1312-1316 NN denotes IKKβ
T7388 1317-1326 NN denotes substrate
T7389 1326-1327 -COMMA- denotes ,
T7390 1328-1330 PRP denotes we
T7391 1331-1340 VB denotes performed
T7392 1341-1353 JJ denotes 32P-labeling
T7393 1354-1356 FW denotes in
T7394 1357-1362 FW denotes vitro
T7395 1363-1369 NN denotes kinase
T7396 1370-1376 NN denotes assays
T7397 1377-1381 IN denotes with
T7398 1382-1393 JJ denotes recombinant
T7399 1394-1403 JJ denotes wild-type
T7400 1404-1406 CC denotes or
T7401 1407-1412 NN denotes S209A
T7402 1413-1419 JJ denotes mutant
T7403 1420-1424 NN denotes RPS3
T7404 1425-1433 NN denotes proteins
T7405 1435-1443 VB denotes Compared
T7406 1444-1448 IN denotes with
T7407 1449-1452 DT denotes the
T7408 1453-1462 JJ denotes wild-type
T7409 1463-1470 NN denotes protein
T7410 1470-1471 -COMMA- denotes ,
T7411 1472-1475 DT denotes the
T7412 1476-1481 NN denotes S209A
T7413 1482-1490 NN denotes mutation
T7414 1491-1498 VB denotes reduced
T7415 1499-1512 JJ denotes IKKβ–mediated
T7416 1513-1517 NN denotes RPS3
T7417 1518-1533 NN denotes phosphorylation
T7418 1534-1535 -LRB- denotes (
T7419 1535-1539 NN denotes Fig.
T7420 1540-1542 NN denotes 4c
T7421 1542-1543 -RRB- denotes )
T7422 1545-1550 EX denotes There
T7423 1551-1556 MD denotes might
T7424 1557-1559 VB denotes be
T7425 1560-1571 JJ denotes alternative
T7426 1572-1587 NN denotes phosphorylation
T7427 1588-1592 NN denotes site
T7428 1592-1593 -LRB- denotes (
T7429 1593-1594 NN denotes s
T7430 1594-1595 -RRB- denotes )
T7431 1596-1601 IN denotes under
T7432 1602-1607 DT denotes these
T7433 1608-1618 NN denotes conditions
T7434 1619-1624 VB denotes given
T7435 1625-1631 JJ denotes modest
T7436 1632-1640 JJ denotes residual
T7437 1641-1655 VB denotes phosphorylated
T7438 1656-1660 NN denotes RPS3
T7439 1661-1662 -LRB- denotes (
T7440 1662-1666 NN denotes Fig.
T7441 1667-1669 NN denotes 4c
T7442 1669-1670 -RRB- denotes )
T7443 1672-1676 NN denotes RPS3
T7444 1677-1681 NN denotes S209
T7445 1682-1686 VB denotes does
T7446 1687-1690 RB denotes not
T7447 1691-1695 VB denotes fall
T7448 1696-1702 IN denotes within
T7449 1703-1704 DT denotes a
T7450 1705-1717 JJ denotes conventional
T7451 1718-1721 NN denotes IKK
T7452 1722-1733 NN denotes recognition
T7453 1734-1739 NN denotes motif
T7454 1739-1740 -COMMA- denotes ,
T7455 1741-1744 CC denotes but
T7456 1745-1751 RB denotes rather
T7457 1752-1759 VB denotes resides
T7458 1760-1762 IN denotes in
T7459 1763-1764 DT denotes a
T7460 1765-1773 NN denotes sequence
T7461 1774-1779 NN denotes motif
T7462 1780-1781 -LRB- denotes (
T7463 1781-1791 NN denotes XXXpS/TXXE
T7464 1791-1792 -RRB- denotes )
T7465 1792-1793 -COMMA- denotes ,
T7466 1794-1805 RB denotes potentially
T7467 1806-1816 VB denotes recognized
T7468 1817-1819 IN denotes by
T7469 1820-1826 NN denotes casein
T7470 1827-1833 NN denotes kinase
T7471 1834-1836 CD denotes II
T7472 1837-1838 -LRB- denotes (
T7473 1838-1841 NN denotes CK2
T7474 1841-1842 -RRB- denotes )
T7475 1844-1852 IN denotes Although
T7476 1853-1857 NN denotes IKKβ
T7477 1858-1864 NN denotes kinase
T7478 1865-1868 MD denotes can
T7479 1869-1876 VB denotes display
T7480 1877-1878 DT denotes a
T7481 1879-1887 JJ denotes CK2-like
T7482 1888-1903 NN denotes phosphorylation
T7483 1904-1917 NN denotes specificity29
T7484 1917-1918 -COMMA- denotes ,
T7485 1919-1921 DT denotes no
T7486 1922-1925 NN denotes CK2
T7487 1926-1933 NN denotes protein
T7488 1934-1937 VB denotes was
T7489 1938-1948 JJ denotes detectable
T7490 1949-1951 IN denotes in
T7491 1952-1955 PRP-DOLLAR- denotes our
T7492 1956-1967 JJ denotes recombinant
T7493 1968-1971 NN denotes IKK
T7494 1972-1980 NN denotes proteins
T7495 1981-1982 -LRB- denotes (
T7496 1982-1995 NNP denotes Supplementary
T7497 1996-2000 NNP denotes Fig.
T7498 2001-2002 CD denotes 6
T7499 2002-2003 -RRB- denotes )
T7500 2005-2009 RB denotes Thus
T7501 2009-2010 -COMMA- denotes ,
T7502 2011-2015 NN denotes RPS3
T7503 2016-2020 NN denotes S209
T7504 2021-2036 NN denotes phosphorylation
T7505 2037-2040 VB denotes was
T7506 2041-2044 JJ denotes due
T7507 2045-2047 TO denotes to
T7508 2048-2051 DT denotes the
T7509 2052-2061 JJ denotes alternate
T7510 2062-2073 NN denotes specificity
T7511 2074-2076 IN denotes of
T7512 2077-2080 DT denotes the
T7513 2081-2085 NN denotes IKKβ
T7514 2086-2092 NN denotes kinase
T7515 2093-2099 RB denotes rather
T7516 2100-2104 IN denotes than
T7517 2105-2108 DT denotes any
T7518 2109-2114 NN denotes trace
T7519 2115-2121 NN denotes amount
T7520 2122-2124 IN denotes of
T7521 2125-2128 NN denotes CK2
T7522 2129-2134 VB denotes bound
T7523 2135-2137 TO denotes to
T7524 2138-2142 NN denotes IKKs
T7525 2144-2146 TO denotes To
T7526 2147-2156 VB denotes determine
T7527 2157-2164 IN denotes whether
T7528 2165-2169 NN denotes S209
T7529 2170-2172 VB denotes is
T7530 2173-2176 DT denotes the
T7531 2177-2185 JJ denotes critical
T7532 2186-2190 NN denotes site
T7533 2191-2193 IN denotes at
T7534 2194-2199 WDT denotes which
T7535 2200-2204 NN denotes IKKβ
T7536 2205-2219 VB denotes phosphorylates
T7537 2220-2224 NN denotes RPS3
T7538 2225-2227 IN denotes in
T7539 2228-2234 VB denotes living
T7540 2235-2240 NN denotes cells
T7541 2240-2241 -COMMA- denotes ,
T7542 2242-2244 PRP denotes we
T7543 2245-2256 VB denotes transfected
T7544 2257-2260 DT denotes the
T7545 2261-2270 JJ denotes wild-type
T7546 2271-2273 CC denotes or
T7547 2274-2279 NN denotes S209A
T7548 2280-2286 JJ denotes mutant
T7549 2287-2296 NN denotes Flag-RPS3
T7550 2297-2302 RB denotes alone
T7551 2302-2303 -COMMA- denotes ,
T7552 2304-2306 CC denotes or
T7553 2307-2315 RB denotes together
T7554 2316-2320 IN denotes with
T7555 2321-2325 NN denotes IKKβ
T7556 2326-2330 IN denotes into
T7557 2331-2336 NN denotes cells
T7558 2338-2344 RB denotes Indeed
T7559 2344-2345 -COMMA- denotes ,
T7560 2346-2348 PRP denotes we
T7561 2349-2357 VB denotes observed
T7562 2358-2362 IN denotes that
T7563 2363-2377 VB denotes overexpressing
T7564 2378-2382 NN denotes IKKβ
T7565 2383-2391 VB denotes enhanced
T7566 2392-2401 NN denotes Flag-RPS3
T7567 2402-2417 NN denotes phosphorylation
T7568 2417-2418 -COMMA- denotes ,
T7569 2419-2422 CC denotes but
T7570 2423-2438 NN denotes phosphorylation
T7571 2439-2442 VB denotes was
T7572 2443-2454 RB denotes effectively
T7573 2455-2465 VB denotes eliminated
T7574 2466-2468 IN denotes by
T7575 2469-2476 NN denotes alanine
T7576 2477-2489 NN denotes substitution
T7577 2490-2500 VB denotes indicating
T7578 2501-2505 IN denotes that
T7579 2506-2510 NN denotes S209
T7580 2511-2513 VB denotes is
T7581 2514-2517 DT denotes the
T7582 2518-2529 JJ denotes predominant
T7583 2530-2536 NN denotes target
T7584 2537-2541 NN denotes site
T7585 2542-2545 IN denotes for
T7586 2546-2550 NN denotes IKKβ
T7587 2551-2566 NN denotes phosphorylation
T7588 2567-2568 -LRB- denotes (
T7589 2568-2572 NNP denotes Fig.
T7590 2573-2575 NN denotes 4d
T7591 2575-2576 -RRB- denotes )
T7592 2578-2580 PRP denotes We
T7593 2581-2585 RB denotes next
T7594 2586-2595 VB denotes generated
T7595 2596-2597 DT denotes a
T7596 2598-2610 NN denotes phospho-S209
T7597 2611-2615 NN denotes RPS3
T7598 2616-2624 NN denotes antibody
T7599 2625-2628 CC denotes and
T7600 2629-2638 VB denotes confirmed
T7601 2639-2643 IN denotes that
T7602 2644-2654 JJ denotes endogenous
T7603 2655-2659 NN denotes RPS3
T7604 2660-2663 VB denotes was
T7605 2664-2678 VB denotes phosphorylated
T7606 2679-2681 IN denotes at
T7607 2682-2686 NN denotes S209
T7608 2687-2689 IN denotes in
T7609 2690-2691 DT denotes a
T7610 2692-2706 JJ denotes time-dependent
T7611 2707-2713 NN denotes manner
T7612 2714-2718 IN denotes upon
T7613 2719-2722 NN denotes TNF
T7614 2723-2734 NN denotes stimulation
T7615 2735-2736 -LRB- denotes (
T7616 2736-2740 NN denotes Fig.
T7617 2741-2743 NN denotes 4e
T7618 2743-2744 -RRB- denotes )
T7619 2746-2750 RB denotes Thus
T7620 2750-2751 -COMMA- denotes ,
T7621 2752-2755 DT denotes the
T7622 2756-2760 NN denotes RPS3
T7623 2761-2771 JJ denotes C-terminal
T7624 2772-2776 NN denotes tail
T7625 2777-2788 RB denotes potentially
T7626 2789-2797 VB denotes contains
T7627 2798-2800 DT denotes an
T7628 2801-2810 JJ denotes important
T7629 2811-2821 JJ denotes regulatory
T7630 2822-2826 NN denotes site
R5650 T7159 T7160 arg1Of IKKβ,phosphorylates
R5651 T7161 T7160 arg2Of RPS3,phosphorylates
R5652 T7161 T7162 arg1Of RPS3,at
R5653 T7163 T7162 arg2Of serine,at
R5654 T7163 T7164 arg1Of serine,209
R5655 T7167 T7165 arg2Of defined,Although
R5656 T7167 T7166 arg1Of defined,originally
R5657 T7167 T7168 arg1Of defined,as
R5658 T7170 T7168 arg2Of kinase,as
R5659 T7170 T7169 arg1Of kinase,the
R5660 T7170 T7171 arg1Of kinase,that
R5661 T7170 T7172 arg1Of kinase,phosphorylates
R5662 T7173 T7172 arg2Of IκB19,phosphorylates
R5663 T7175 T7177 arg1Of IKKβ,phosphorylates
R5664 T7177 T7165 arg1Of phosphorylates,Although
R5665 T7177 T7174 arg1Of phosphorylates,","
R5666 T7177 T7176 arg1Of phosphorylates,also
R5667 T7179 T7177 arg2Of substrates,phosphorylates
R5668 T7179 T7178 arg1Of substrates,unrelated
R5669 T7179 T7180 arg1Of substrates,including
R5670 T7181 T7182 arg1Of 14-3-3β,and
R5671 T7182 T7180 arg2Of and,including
R5672 T7182 T7184 arg1Of and,","
R5673 T7182 T7185 arg1Of and,which
R5674 T7182 T7186 arg1Of and,lack
R5675 T7183 T7182 arg2Of Bcl10,and
R5676 T7190 T7186 arg2Of motif,lack
R5677 T7190 T7187 arg1Of motif,the
R5678 T7190 T7188 arg1Of motif,IKK
R5679 T7190 T7189 arg1Of motif,consensus
R5680 T7190 T7191 arg1Of motif,(
R5681 T7190 T7194 arg1Of motif,28
R5682 T7192 T7191 arg2Of DpSGYXpS/T,(
R5683 T7193 T7191 arg3Of ),(
R5684 T7195 T7197 arg1Of We,hypothesized
R5685 T7197 T7196 arg1Of hypothesized,therefore
R5686 T7199 T7200 arg1Of IKKβ,could
R5687 T7199 T7202 arg1Of IKKβ,phosphorylate
R5688 T7202 T7197 arg2Of phosphorylate,hypothesized
R5689 T7202 T7198 arg1Of phosphorylate,that
R5690 T7202 T7200 arg2Of phosphorylate,could
R5691 T7202 T7201 arg1Of phosphorylate,directly
R5692 T7203 T7202 arg2Of RPS3,phosphorylate
R5693 T7206 T7205 arg1Of vitro,in
R5694 T7208 T7204 arg2Of assays,By
R5695 T7208 T7206 arg1Of assays,vitro
R5696 T7208 T7207 arg1Of assays,kinase
R5697 T7208 T7209 arg1Of assays,using
R5698 T7211 T7212 arg1Of IKK,and
R5699 T7213 T7212 arg2Of RPS3,and
R5700 T7214 T7209 arg2Of proteins,using
R5701 T7214 T7210 arg1Of proteins,recombinant
R5702 T7214 T7211 arg1Of proteins,IKK
R5703 T7214 T7213 arg1Of proteins,RPS3
R5704 T7216 T7217 arg1Of we,observed
R5705 T7217 T7204 arg1Of observed,By
R5706 T7217 T7215 arg1Of observed,","
R5707 T7217 T7263 arg1Of observed,","
R5708 T7217 T7264 arg1Of observed,when
R5709 T7219 T7218 arg1Of incorporation,strong
R5710 T7219 T7220 arg1Of incorporation,of
R5711 T7219 T7222 arg1Of incorporation,in
R5712 T7219 T7225 arg1Of incorporation,and
R5713 T7221 T7220 arg2Of 32P,of
R5714 T7224 T7222 arg2Of IKKα,in
R5715 T7224 T7223 arg1Of IKKα,autophosphorylatd
R5716 T7225 T7236 arg1Of and,as
R5717 T7226 T7225 arg2Of IKKβ,and
R5718 T7226 T7227 arg1Of IKKβ,(
R5719 T7229 T7227 arg2Of 4a,(
R5720 T7229 T7228 arg1Of 4a,Fig.
R5721 T7229 T7230 arg1Of 4a,","
R5722 T7231 T7230 arg2Of lanes,","
R5723 T7231 T7232 arg1Of lanes,2-7
R5724 T7233 T7227 arg3Of ),(
R5725 T7236 T7217 arg2Of as,observed
R5726 T7236 T7234 arg1Of as,as
R5727 T7236 T7235 arg1Of as,well
R5728 T7238 T7237 arg2Of GST-IκBα,phosporylated
R5729 T7238 T7239 arg1Of GST-IκBα,(
R5730 T7238 T7242 arg1Of GST-IκBα,(
R5731 T7238 T7248 arg1Of GST-IκBα,but
R5732 T7240 T7239 arg2Of 1-54,(
R5733 T7241 T7239 arg3Of ),(
R5734 T7244 T7242 arg2Of Fig.,(
R5735 T7244 T7243 arg1Of Fig.,Supplementary
R5736 T7244 T7245 arg1Of Fig.,4
R5737 T7246 T7242 arg3Of ),(
R5738 T7248 T7236 arg2Of but,as
R5739 T7248 T7247 arg1Of but,","
R5740 T7248 T7249 arg1Of but,not
R5741 T7252 T7248 arg2Of protein,but
R5742 T7252 T7250 arg1Of protein,the
R5743 T7252 T7251 arg1Of protein,GST
R5744 T7252 T7253 arg1Of protein,alone
R5745 T7252 T7254 arg1Of protein,(
R5746 T7256 T7255 arg1Of 4a,Fig.
R5747 T7256 T7257 arg1Of 4a,","
R5748 T7257 T7254 arg2Of ",",(
R5749 T7259 T7260 arg1Of 3,and
R5750 T7260 T7257 arg2Of and,","
R5751 T7260 T7258 arg1Of and,lanes
R5752 T7261 T7260 arg2Of 6,and
R5753 T7262 T7254 arg3Of ),(
R5754 T7266 T7267 arg1Of IKKα,or
R5755 T7267 T7265 arg1Of or,either
R5756 T7267 T7269 arg1Of or,was
R5757 T7267 T7270 arg2Of or,used
R5758 T7268 T7267 arg2Of IKKβ,or
R5759 T7270 T7264 arg2Of used,when
R5760 T7270 T7269 arg2Of used,was
R5761 T7271 T7272 arg1Of We,discovered
R5762 T7274 T7275 arg1Of GST-RPS3,could
R5763 T7274 T7276 arg1Of GST-RPS3,be
R5764 T7274 T7277 arg2Of GST-RPS3,phosphorylated
R5765 T7277 T7272 arg2Of phosphorylated,discovered
R5766 T7277 T7273 arg1Of phosphorylated,that
R5767 T7277 T7275 arg2Of phosphorylated,could
R5768 T7277 T7276 arg2Of phosphorylated,be
R5769 T7279 T7281 arg1Of IKKβ,but
R5770 T7281 T7277 arg1Of but,phosphorylated
R5771 T7281 T7278 arg2Of but,by
R5772 T7281 T7280 arg1Of but,","
R5773 T7281 T7282 arg1Of but,not
R5774 T7281 T7284 arg1Of but,","
R5775 T7281 T7286 arg1Of but,vitro
R5776 T7281 T7287 arg1Of but,(
R5777 T7283 T7281 arg2Of IKKα,but
R5778 T7286 T7285 arg1Of vitro,in
R5779 T7289 T7287 arg2Of 4a,(
R5780 T7289 T7288 arg1Of 4a,Fig.
R5781 T7289 T7290 arg1Of 4a,","
R5782 T7293 T7294 arg1Of 4,and
R5783 T7294 T7290 arg2Of and,","
R5784 T7294 T7291 arg1Of and,compare
R5785 T7294 T7292 arg1Of and,lanes
R5786 T7295 T7294 arg2Of 7,and
R5787 T7296 T7287 arg3Of ),(
R5788 T7298 T7297 arg1Of identify,To
R5789 T7303 T7298 arg2Of residue,identify
R5790 T7303 T7299 arg1Of residue,the
R5791 T7303 T7300 arg1Of residue,RPS3
R5792 T7303 T7301 arg1Of residue,amino
R5793 T7303 T7302 arg1Of residue,acid
R5794 T7303 T7304 arg1Of residue,(
R5795 T7303 T7307 arg2Of residue,phosphorylated
R5796 T7305 T7304 arg2Of s,(
R5797 T7306 T7304 arg3Of ),(
R5798 T7309 T7307 arg1Of IKKβ,phosphorylated
R5799 T7309 T7308 arg2Of IKKβ,by
R5800 T7311 T7298 arg1Of we,identify
R5801 T7311 T7312 arg1Of we,performed
R5802 T7312 T7297 modOf performed,To
R5803 T7312 T7310 arg1Of performed,","
R5804 T7317 T7312 arg2Of analyses,performed
R5805 T7317 T7313 arg1Of analyses,liquid
R5806 T7317 T7314 arg1Of analyses,chromatography-tandem
R5807 T7317 T7315 arg1Of analyses,mass
R5808 T7317 T7316 arg1Of analyses,spectrometry
R5809 T7317 T7318 arg1Of analyses,using
R5810 T7318 T7320 arg1Of using,vitro
R5811 T7320 T7319 arg1Of vitro,in
R5812 T7322 T7318 arg2Of RPS3,using
R5813 T7322 T7321 arg2Of RPS3,phosphorylated
R5814 T7324 T7325 arg1Of results,indicated
R5815 T7327 T7325 arg2Of IKKβ,indicated
R5816 T7327 T7326 arg1Of IKKβ,that
R5817 T7328 T7325 arg3Of phosphorylated,indicated
R5818 T7329 T7323 arg1Of S209,The
R5819 T7329 T7328 arg2Of S209,phosphorylated
R5820 T7329 T7330 arg1Of S209,","
R5821 T7329 T7331 arg1Of S209,located
R5822 T7331 T7332 arg1Of located,in
R5823 T7335 T7332 arg2Of C-terminus,in
R5824 T7335 T7333 arg1Of C-terminus,the
R5825 T7335 T7334 arg1Of C-terminus,RPS3
R5826 T7335 T7336 arg1Of C-terminus,(
R5827 T7338 T7336 arg2Of 4b,(
R5828 T7338 T7337 arg1Of 4b,Fig.
R5829 T7339 T7336 arg3Of ),(
R5830 T7344 T7340 arg1Of alignment,RPS3
R5831 T7344 T7341 arg1Of alignment,amino
R5832 T7344 T7342 arg1Of alignment,acid
R5833 T7344 T7343 arg1Of alignment,sequence
R5834 T7344 T7345 arg1Of alignment,revealed
R5835 T7347 T7348 arg1Of S209,is
R5836 T7347 T7349 arg2Of S209,conserved
R5837 T7349 T7345 arg2Of conserved,revealed
R5838 T7349 T7346 arg1Of conserved,that
R5839 T7349 T7348 arg2Of conserved,is
R5840 T7349 T7350 arg1Of conserved,in
R5841 T7349 T7353 arg1Of conserved,throughout
R5842 T7352 T7350 arg2Of species,in
R5843 T7352 T7351 arg1Of species,many
R5844 T7354 T7353 arg2Of phylogeny,throughout
R5845 T7354 T7355 arg1Of phylogeny,with
R5846 T7357 T7355 arg2Of exception,with
R5847 T7357 T7356 arg1Of exception,the
R5848 T7357 T7358 arg1Of exception,of
R5849 T7357 T7364 arg1Of exception,","
R5850 T7360 T7359 arg1Of elegans,Caenorhabditis
R5851 T7360 T7361 arg1Of elegans,and
R5852 T7361 T7358 arg2Of and,of
R5853 T7363 T7361 arg2Of pombe,and
R5854 T7363 T7362 arg1Of pombe,Schizosaccharomyces
R5855 T7366 T7364 arg2Of organisms,","
R5856 T7366 T7365 arg1Of organisms,two
R5857 T7366 T7367 arg1Of organisms,that
R5858 T7366 T7368 arg1Of organisms,do
R5859 T7366 T7370 arg1Of organisms,possess
R5860 T7370 T7368 arg2Of possess,do
R5861 T7370 T7369 arg1Of possess,not
R5862 T7370 T7375 arg1Of possess,(
R5863 T7374 T7370 arg2Of pathway,possess
R5864 T7374 T7371 arg1Of pathway,the
R5865 T7374 T7372 arg1Of pathway,NF-κB
R5866 T7374 T7373 arg1Of pathway,signal
R5867 T7377 T7375 arg2Of Fig.,(
R5868 T7377 T7376 arg1Of Fig.,Supplementary
R5869 T7377 T7378 arg1Of Fig.,5
R5870 T7379 T7375 arg3Of ),(
R5871 T7381 T7380 arg1Of verify,To
R5872 T7381 T7382 arg1Of verify,biochemically
R5873 T7384 T7385 arg1Of S209,is
R5874 T7385 T7381 arg2Of is,verify
R5875 T7385 T7383 arg1Of is,that
R5876 T7388 T7385 arg2Of substrate,is
R5877 T7388 T7386 arg1Of substrate,an
R5878 T7388 T7387 arg1Of substrate,IKKβ
R5879 T7390 T7381 arg1Of we,verify
R5880 T7390 T7391 arg1Of we,performed
R5881 T7391 T7380 modOf performed,To
R5882 T7391 T7389 arg1Of performed,","
R5883 T7394 T7393 arg1Of vitro,in
R5884 T7396 T7391 arg2Of assays,performed
R5885 T7396 T7392 arg1Of assays,32P-labeling
R5886 T7396 T7394 arg1Of assays,vitro
R5887 T7396 T7395 arg1Of assays,kinase
R5888 T7396 T7397 arg1Of assays,with
R5889 T7399 T7398 arg1Of wild-type,recombinant
R5890 T7399 T7400 arg1Of wild-type,or
R5891 T7400 T7397 arg2Of or,with
R5892 T7404 T7400 arg2Of proteins,or
R5893 T7404 T7401 arg1Of proteins,S209A
R5894 T7404 T7402 arg1Of proteins,mutant
R5895 T7404 T7403 arg1Of proteins,RPS3
R5896 T7406 T7405 arg2Of with,Compared
R5897 T7409 T7406 arg2Of protein,with
R5898 T7409 T7407 arg1Of protein,the
R5899 T7409 T7408 arg1Of protein,wild-type
R5900 T7413 T7411 arg1Of mutation,the
R5901 T7413 T7412 arg1Of mutation,S209A
R5902 T7413 T7414 arg1Of mutation,reduced
R5903 T7414 T7405 arg1Of reduced,Compared
R5904 T7414 T7410 arg1Of reduced,","
R5905 T7417 T7414 arg2Of phosphorylation,reduced
R5906 T7417 T7415 arg1Of phosphorylation,IKKβ–mediated
R5907 T7417 T7416 arg1Of phosphorylation,RPS3
R5908 T7417 T7418 arg1Of phosphorylation,(
R5909 T7420 T7418 arg2Of 4c,(
R5910 T7420 T7419 arg1Of 4c,Fig.
R5911 T7421 T7418 arg3Of ),(
R5912 T7422 T7423 arg1Of There,might
R5913 T7422 T7424 arg1Of There,be
R5914 T7424 T7423 arg2Of be,might
R5915 T7424 T7431 arg1Of be,under
R5916 T7424 T7434 arg1Of be,given
R5917 T7427 T7424 arg2Of site,be
R5918 T7427 T7425 arg1Of site,alternative
R5919 T7427 T7426 arg1Of site,phosphorylation
R5920 T7427 T7428 arg1Of site,(
R5921 T7429 T7428 arg2Of s,(
R5922 T7430 T7428 arg3Of ),(
R5923 T7433 T7431 arg2Of conditions,under
R5924 T7433 T7432 arg1Of conditions,these
R5925 T7438 T7434 arg2Of RPS3,given
R5926 T7438 T7435 arg1Of RPS3,modest
R5927 T7438 T7436 arg1Of RPS3,residual
R5928 T7438 T7437 arg2Of RPS3,phosphorylated
R5929 T7438 T7439 arg1Of RPS3,(
R5930 T7441 T7439 arg2Of 4c,(
R5931 T7441 T7440 arg1Of 4c,Fig.
R5932 T7442 T7439 arg3Of ),(
R5933 T7444 T7443 arg1Of S209,RPS3
R5934 T7444 T7445 arg1Of S209,does
R5935 T7444 T7447 arg1Of S209,fall
R5936 T7444 T7457 arg1Of S209,resides
R5937 T7447 T7445 arg2Of fall,does
R5938 T7447 T7446 arg1Of fall,not
R5939 T7447 T7448 arg1Of fall,within
R5940 T7447 T7455 arg1Of fall,but
R5941 T7453 T7448 arg2Of motif,within
R5942 T7453 T7449 arg1Of motif,a
R5943 T7453 T7450 arg1Of motif,conventional
R5944 T7453 T7451 arg1Of motif,IKK
R5945 T7453 T7452 arg1Of motif,recognition
R5946 T7455 T7454 arg1Of but,","
R5947 T7457 T7455 arg2Of resides,but
R5948 T7457 T7456 arg1Of resides,rather
R5949 T7457 T7458 arg1Of resides,in
R5950 T7461 T7458 arg2Of motif,in
R5951 T7461 T7459 arg1Of motif,a
R5952 T7461 T7460 arg1Of motif,sequence
R5953 T7461 T7462 arg1Of motif,(
R5954 T7461 T7465 arg1Of motif,","
R5955 T7461 T7467 arg2Of motif,recognized
R5956 T7463 T7462 arg2Of XXXpS/TXXE,(
R5957 T7464 T7462 arg3Of ),(
R5958 T7467 T7466 arg1Of recognized,potentially
R5959 T7470 T7467 arg1Of kinase,recognized
R5960 T7470 T7468 arg2Of kinase,by
R5961 T7470 T7469 arg1Of kinase,casein
R5962 T7470 T7471 arg1Of kinase,II
R5963 T7470 T7472 arg1Of kinase,(
R5964 T7473 T7472 arg2Of CK2,(
R5965 T7474 T7472 arg3Of ),(
R5966 T7477 T7476 arg1Of kinase,IKKβ
R5967 T7477 T7478 arg1Of kinase,can
R5968 T7477 T7479 arg1Of kinase,display
R5969 T7479 T7475 arg2Of display,Although
R5970 T7479 T7478 arg2Of display,can
R5971 T7483 T7479 arg2Of specificity29,display
R5972 T7483 T7480 arg1Of specificity29,a
R5973 T7483 T7481 arg1Of specificity29,CK2-like
R5974 T7483 T7482 arg1Of specificity29,phosphorylation
R5975 T7487 T7485 arg1Of protein,no
R5976 T7487 T7486 arg1Of protein,CK2
R5977 T7487 T7488 arg1Of protein,was
R5978 T7487 T7489 arg1Of protein,detectable
R5979 T7488 T7475 arg1Of was,Although
R5980 T7488 T7484 arg1Of was,","
R5981 T7488 T7490 arg1Of was,in
R5982 T7489 T7488 arg2Of detectable,was
R5983 T7494 T7490 arg2Of proteins,in
R5984 T7494 T7491 arg1Of proteins,our
R5985 T7494 T7492 arg1Of proteins,recombinant
R5986 T7494 T7493 arg1Of proteins,IKK
R5987 T7494 T7495 arg1Of proteins,(
R5988 T7497 T7495 arg2Of Fig.,(
R5989 T7497 T7496 arg1Of Fig.,Supplementary
R5990 T7497 T7498 arg1Of Fig.,6
R5991 T7499 T7495 arg3Of ),(
R5992 T7504 T7502 arg1Of phosphorylation,RPS3
R5993 T7504 T7503 arg1Of phosphorylation,S209
R5994 T7504 T7505 arg1Of phosphorylation,was
R5995 T7504 T7506 arg1Of phosphorylation,due
R5996 T7505 T7500 arg1Of was,Thus
R5997 T7505 T7501 arg1Of was,","
R5998 T7506 T7505 arg2Of due,was
R5999 T7506 T7507 arg1Of due,to
R6000 T7510 T7508 arg1Of specificity,the
R6001 T7510 T7509 arg1Of specificity,alternate
R6002 T7510 T7511 arg1Of specificity,of
R6003 T7510 T7516 arg1Of specificity,than
R6004 T7514 T7511 arg2Of kinase,of
R6005 T7514 T7512 arg1Of kinase,the
R6006 T7514 T7513 arg1Of kinase,IKKβ
R6007 T7516 T7507 arg2Of than,to
R6008 T7516 T7515 arg1Of than,rather
R6009 T7519 T7516 arg2Of amount,than
R6010 T7519 T7517 arg1Of amount,any
R6011 T7519 T7518 arg1Of amount,trace
R6012 T7519 T7520 arg1Of amount,of
R6013 T7519 T7522 arg2Of amount,bound
R6014 T7521 T7520 arg2Of CK2,of
R6015 T7522 T7523 arg1Of bound,to
R6016 T7524 T7523 arg2Of IKKs,to
R6017 T7526 T7525 arg1Of determine,To
R6018 T7528 T7529 arg1Of S209,is
R6019 T7529 T7526 arg2Of is,determine
R6020 T7529 T7527 arg1Of is,whether
R6021 T7532 T7529 arg2Of site,is
R6022 T7532 T7530 arg1Of site,the
R6023 T7532 T7531 arg1Of site,critical
R6024 T7532 T7533 arg2Of site,at
R6025 T7532 T7534 arg1Of site,which
R6026 T7535 T7536 arg1Of IKKβ,phosphorylates
R6027 T7536 T7533 arg1Of phosphorylates,at
R6028 T7536 T7538 arg1Of phosphorylates,in
R6029 T7537 T7536 arg2Of RPS3,phosphorylates
R6030 T7540 T7538 arg2Of cells,in
R6031 T7540 T7539 arg1Of cells,living
R6032 T7542 T7526 arg1Of we,determine
R6033 T7542 T7543 arg1Of we,transfected
R6034 T7543 T7525 modOf transfected,To
R6035 T7543 T7541 arg1Of transfected,","
R6036 T7549 T7543 arg2Of Flag-RPS3,transfected
R6037 T7549 T7544 arg1Of Flag-RPS3,the
R6038 T7549 T7545 arg1Of Flag-RPS3,wild-type
R6039 T7549 T7546 arg1Of Flag-RPS3,or
R6040 T7549 T7547 arg1Of Flag-RPS3,S209A
R6041 T7549 T7548 arg1Of Flag-RPS3,mutant
R6042 T7549 T7550 arg1Of Flag-RPS3,alone
R6043 T7549 T7553 arg1Of Flag-RPS3,together
R6044 T7549 T7556 arg1Of Flag-RPS3,into
R6045 T7550 T7552 arg1Of alone,or
R6046 T7552 T7551 arg1Of or,","
R6047 T7552 T7554 arg1Of or,with
R6048 T7553 T7552 arg2Of together,or
R6049 T7555 T7554 arg2Of IKKβ,with
R6050 T7557 T7556 arg2Of cells,into
R6051 T7560 T7561 arg1Of we,observed
R6052 T7561 T7558 arg1Of observed,Indeed
R6053 T7561 T7559 arg1Of observed,","
R6054 T7564 T7563 arg1Of IKKβ,overexpressing
R6055 T7564 T7565 arg1Of IKKβ,enhanced
R6056 T7565 T7569 arg1Of enhanced,but
R6057 T7567 T7565 arg2Of phosphorylation,enhanced
R6058 T7567 T7566 arg1Of phosphorylation,Flag-RPS3
R6059 T7569 T7561 arg2Of but,observed
R6060 T7569 T7562 arg1Of but,that
R6061 T7569 T7568 arg1Of but,","
R6062 T7570 T7571 arg1Of phosphorylation,was
R6063 T7570 T7573 arg2Of phosphorylation,eliminated
R6064 T7573 T7569 arg2Of eliminated,but
R6065 T7573 T7571 arg2Of eliminated,was
R6066 T7573 T7572 arg1Of eliminated,effectively
R6067 T7576 T7573 arg1Of substitution,eliminated
R6068 T7576 T7574 arg2Of substitution,by
R6069 T7576 T7575 arg1Of substitution,alanine
R6070 T7576 T7577 arg1Of substitution,indicating
R6071 T7579 T7580 arg1Of S209,is
R6072 T7580 T7577 arg2Of is,indicating
R6073 T7580 T7578 arg1Of is,that
R6074 T7584 T7580 arg2Of site,is
R6075 T7584 T7581 arg1Of site,the
R6076 T7584 T7582 arg1Of site,predominant
R6077 T7584 T7583 arg1Of site,target
R6078 T7584 T7585 arg1Of site,for
R6079 T7587 T7585 arg2Of phosphorylation,for
R6080 T7587 T7586 arg1Of phosphorylation,IKKβ
R6081 T7587 T7588 arg1Of phosphorylation,(
R6082 T7590 T7588 arg2Of 4d,(
R6083 T7590 T7589 arg1Of 4d,Fig.
R6084 T7591 T7588 arg3Of ),(
R6085 T7592 T7594 arg1Of We,generated
R6086 T7592 T7600 arg1Of We,confirmed
R6087 T7594 T7599 arg1Of generated,and
R6088 T7598 T7594 arg2Of antibody,generated
R6089 T7598 T7595 arg1Of antibody,a
R6090 T7598 T7596 arg1Of antibody,phospho-S209
R6091 T7598 T7597 arg1Of antibody,RPS3
R6092 T7599 T7593 arg1Of and,next
R6093 T7600 T7599 arg2Of confirmed,and
R6094 T7603 T7602 arg1Of RPS3,endogenous
R6095 T7603 T7604 arg1Of RPS3,was
R6096 T7603 T7605 arg2Of RPS3,phosphorylated
R6097 T7605 T7600 arg2Of phosphorylated,confirmed
R6098 T7605 T7601 arg1Of phosphorylated,that
R6099 T7605 T7604 arg2Of phosphorylated,was
R6100 T7605 T7606 arg1Of phosphorylated,at
R6101 T7605 T7608 arg1Of phosphorylated,in
R6102 T7605 T7612 arg1Of phosphorylated,upon
R6103 T7607 T7606 arg2Of S209,at
R6104 T7611 T7608 arg2Of manner,in
R6105 T7611 T7609 arg1Of manner,a
R6106 T7611 T7610 arg1Of manner,time-dependent
R6107 T7614 T7612 arg2Of stimulation,upon
R6108 T7614 T7613 arg1Of stimulation,TNF
R6109 T7614 T7615 arg1Of stimulation,(
R6110 T7617 T7615 arg2Of 4e,(
R6111 T7617 T7616 arg1Of 4e,Fig.
R6112 T7618 T7615 arg3Of ),(
R6113 T7624 T7621 arg1Of tail,the
R6114 T7624 T7622 arg1Of tail,RPS3
R6115 T7624 T7623 arg1Of tail,C-terminal
R6116 T7624 T7626 arg1Of tail,contains
R6117 T7626 T7619 arg1Of contains,Thus
R6118 T7626 T7620 arg1Of contains,","
R6119 T7626 T7625 arg1Of contains,potentially
R6120 T7630 T7626 arg2Of site,contains
R6121 T7630 T7627 arg1Of site,an
R6122 T7630 T7628 arg1Of site,important
R6123 T7630 T7629 arg1Of site,regulatory

bionlp-st-ge-2016-coref

Id Subject Object Predicate Lexical cue
T7631 2423-2438 Anaphor denotes phosphorylation
T7632 2402-2417 Antecedent denotes phosphorylation
R6124 T7631 T7632 boundBy phosphorylation,phosphorylation

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T7671 0-4 NNP denotes IKKβ
T7672 5-19 VBZ denotes phosphorylates
T7673 20-24 CD denotes RPS3
T7674 25-27 IN denotes at
T7675 28-34 NN denotes serine
T7676 35-38 CD denotes 209
T7677 39-47 IN denotes Although
T7678 48-58 RB denotes originally
T7679 59-66 VBN denotes defined
T7680 67-69 IN denotes as
T7681 70-73 DT denotes the
T7682 74-80 NN denotes kinase
T7683 81-85 WDT denotes that
T7684 86-100 VBZ denotes phosphorylates
T7685 101-106 NNP denotes IκB19
T7686 106-107 , denotes ,
T7687 108-112 NNP denotes IKKβ
T7688 113-117 RB denotes also
T7689 118-132 VBZ denotes phosphorylates
T7690 133-142 JJ denotes unrelated
T7691 143-153 NNS denotes substrates
T7692 154-163 VBG denotes including
T7693 164-171 JJ denotes 14-3-3β
T7694 172-175 CC denotes and
T7695 176-181 JJ denotes Bcl10
T7696 181-182 , denotes ,
T7697 183-188 WDT denotes which
T7698 189-193 VBP denotes lack
T7699 194-197 DT denotes the
T7700 198-201 NNP denotes IKK
T7701 202-211 NN denotes consensus
T7702 212-217 NN denotes motif
T7703 218-219 -LRB- denotes (
T7704 219-229 NNP denotes DpSGYXpS/T
T7705 229-230 -RRB- denotes )
T7706 230-232 CD denotes 28
T7707 232-233 . denotes .
T7708 234-236 PRP denotes We
T7709 237-246 RB denotes therefore
T7710 247-259 VBD denotes hypothesized
T7711 260-264 IN denotes that
T7712 265-269 NNP denotes IKKβ
T7713 270-275 MD denotes could
T7714 276-284 RB denotes directly
T7715 285-298 VB denotes phosphorylate
T7716 299-303 NNP denotes RPS3
T7717 303-304 . denotes .
T7718 305-307 IN denotes By
T7719 308-310 IN denotes in
T7720 311-316 NN denotes vitro
T7721 317-323 NN denotes kinase
T7722 324-330 VBZ denotes assays
T7723 331-336 VBG denotes using
T7724 337-348 JJ denotes recombinant
T7725 349-352 NNP denotes IKK
T7726 353-356 CC denotes and
T7727 357-361 NNP denotes RPS3
T7728 362-370 NNS denotes proteins
T7729 370-371 , denotes ,
T7730 372-374 PRP denotes we
T7731 375-383 VBD denotes observed
T7732 384-390 JJ denotes strong
T7733 391-404 NN denotes incorporation
T7734 405-407 IN denotes of
T7735 408-411 NNP denotes 32P
T7736 412-414 IN denotes in
T7737 415-432 NN denotes autophosphorylatd
T7738 433-437 NNP denotes IKKα
T7739 438-441 CC denotes and
T7740 442-446 NNP denotes IKKβ
T7741 447-448 -LRB- denotes (
T7742 448-452 NNP denotes Fig.
T7743 453-455 CD denotes 4a
T7744 455-456 , denotes ,
T7745 457-462 NNS denotes lanes
T7746 463-466 JJ denotes 2-7
T7747 466-467 -RRB- denotes )
T7748 468-470 RB denotes as
T7749 471-475 RB denotes well
T7750 476-478 IN denotes as
T7751 479-492 VBN denotes phosporylated
T7752 493-501 NNP denotes GST-IκBα
T7753 502-503 -LRB- denotes (
T7754 503-507 CD denotes 1-54
T7755 507-508 -RRB- denotes )
T7756 509-510 -LRB- denotes (
T7757 510-523 NNP denotes Supplementary
T7758 524-528 NNP denotes Fig.
T7759 529-530 LS denotes 4
T7760 530-531 -RRB- denotes )
T7761 531-532 , denotes ,
T7762 533-536 CC denotes but
T7763 537-540 RB denotes not
T7764 541-544 DT denotes the
T7765 545-548 NNP denotes GST
T7766 549-556 NN denotes protein
T7767 557-562 RB denotes alone
T7768 563-564 -LRB- denotes (
T7769 564-568 NNP denotes Fig.
T7770 569-571 CD denotes 4a
T7771 571-572 , denotes ,
T7772 573-578 NNS denotes lanes
T7773 579-580 CD denotes 3
T7774 581-584 CC denotes and
T7775 585-586 CD denotes 6
T7776 586-587 -RRB- denotes )
T7777 587-588 , denotes ,
T7778 589-593 WRB denotes when
T7779 594-600 CC denotes either
T7780 601-605 NNP denotes IKKα
T7781 606-608 CC denotes or
T7782 609-613 NNP denotes IKKβ
T7783 614-617 VBD denotes was
T7784 618-622 VBN denotes used
T7785 622-623 . denotes .
T7786 624-626 PRP denotes We
T7787 627-637 VBD denotes discovered
T7788 638-642 IN denotes that
T7789 643-651 NN denotes GST-RPS3
T7790 652-657 MD denotes could
T7791 658-660 VB denotes be
T7792 661-675 VBN denotes phosphorylated
T7793 676-678 IN denotes by
T7794 679-683 NNP denotes IKKβ
T7795 683-684 , denotes ,
T7796 685-688 CC denotes but
T7797 689-692 RB denotes not
T7798 693-697 NNP denotes IKKα
T7799 697-698 , denotes ,
T7800 699-701 IN denotes in
T7801 702-707 NN denotes vitro
T7802 708-709 -LRB- denotes (
T7803 709-713 NNP denotes Fig.
T7804 714-716 CD denotes 4a
T7805 716-717 , denotes ,
T7806 718-725 VBP denotes compare
T7807 726-731 NNS denotes lanes
T7808 732-733 CD denotes 4
T7809 734-737 CC denotes and
T7810 738-739 CD denotes 7
T7811 739-740 -RRB- denotes )
T7812 740-741 . denotes .
T7813 742-744 TO denotes To
T7814 745-753 VB denotes identify
T7815 754-757 DT denotes the
T7816 758-762 JJ denotes RPS3
T7817 763-768 JJ denotes amino
T7818 769-773 NN denotes acid
T7819 774-781 NN denotes residue
T7820 781-782 -LRB- denotes (
T7821 782-783 PRP denotes s
T7822 783-784 -RRB- denotes )
T7823 785-799 VBN denotes phosphorylated
T7824 800-802 IN denotes by
T7825 803-807 NNP denotes IKKβ
T7826 807-808 , denotes ,
T7827 809-811 PRP denotes we
T7828 812-821 VBD denotes performed
T7829 822-828 JJ denotes liquid
T7830 829-850 NN denotes chromatography-tandem
T7831 851-855 NN denotes mass
T7832 856-868 NN denotes spectrometry
T7833 869-877 VBZ denotes analyses
T7834 878-883 VBG denotes using
T7835 884-886 IN denotes in
T7836 887-892 NN denotes vitro
T7837 893-907 VBN denotes phosphorylated
T7838 908-912 NNP denotes RPS3
T7839 912-913 . denotes .
T7840 914-917 DT denotes The
T7841 918-925 NNS denotes results
T7842 926-935 VBD denotes indicated
T7843 936-940 IN denotes that
T7844 941-945 NNP denotes IKKβ
T7845 946-960 VBD denotes phosphorylated
T7846 961-965 CD denotes S209
T7847 965-966 , denotes ,
T7848 967-974 VBN denotes located
T7849 975-977 IN denotes in
T7850 978-981 DT denotes the
T7851 982-986 NNP denotes RPS3
T7852 987-997 NNP denotes C-terminus
T7853 998-999 -LRB- denotes (
T7854 999-1003 NNP denotes Fig.
T7855 1004-1006 CD denotes 4b
T7856 1006-1007 -RRB- denotes )
T7857 1007-1008 . denotes .
T7858 1009-1013 CD denotes RPS3
T7859 1014-1019 JJ denotes amino
T7860 1020-1024 NN denotes acid
T7861 1025-1033 NN denotes sequence
T7862 1034-1043 NN denotes alignment
T7863 1044-1052 VBD denotes revealed
T7864 1053-1057 IN denotes that
T7865 1058-1062 CD denotes S209
T7866 1063-1065 VBZ denotes is
T7867 1066-1075 VBN denotes conserved
T7868 1076-1078 IN denotes in
T7869 1079-1083 JJ denotes many
T7870 1084-1091 NNS denotes species
T7871 1092-1102 IN denotes throughout
T7872 1103-1112 NN denotes phylogeny
T7873 1113-1117 IN denotes with
T7874 1118-1121 DT denotes the
T7875 1122-1131 NN denotes exception
T7876 1132-1134 IN denotes of
T7877 1135-1149 NNP denotes Caenorhabditis
T7878 1150-1157 NNS denotes elegans
T7879 1158-1161 CC denotes and
T7880 1162-1181 NNS denotes Schizosaccharomyces
T7881 1182-1187 VBP denotes pombe
T7882 1187-1188 , denotes ,
T7883 1189-1192 CD denotes two
T7884 1193-1202 NNS denotes organisms
T7885 1203-1207 WDT denotes that
T7886 1208-1210 VBP denotes do
T7887 1211-1214 RB denotes not
T7888 1215-1222 VB denotes possess
T7889 1223-1226 DT denotes the
T7890 1227-1232 JJ denotes NF-κB
T7891 1233-1239 NN denotes signal
T7892 1240-1247 NN denotes pathway
T7893 1248-1249 -LRB- denotes (
T7894 1249-1262 NNP denotes Supplementary
T7895 1263-1267 NNP denotes Fig.
T7896 1268-1269 CD denotes 5
T7897 1269-1270 -RRB- denotes )
T7898 1270-1271 . denotes .
T7899 1272-1274 TO denotes To
T7900 1275-1281 VB denotes verify
T7901 1282-1295 RB denotes biochemically
T7902 1296-1300 IN denotes that
T7903 1301-1305 CD denotes S209
T7904 1306-1308 VBZ denotes is
T7905 1309-1311 DT denotes an
T7906 1312-1316 JJ denotes IKKβ
T7907 1317-1326 NN denotes substrate
T7908 1326-1327 , denotes ,
T7909 1328-1330 PRP denotes we
T7910 1331-1340 VBD denotes performed
T7911 1341-1353 NN denotes 32P-labeling
T7912 1354-1356 IN denotes in
T7913 1357-1362 NN denotes vitro
T7914 1363-1369 NN denotes kinase
T7915 1370-1376 NNS denotes assays
T7916 1377-1381 IN denotes with
T7917 1382-1393 JJ denotes recombinant
T7918 1394-1403 JJ denotes wild-type
T7919 1404-1406 CC denotes or
T7920 1407-1412 JJ denotes S209A
T7921 1413-1419 JJ denotes mutant
T7922 1420-1424 NN denotes RPS3
T7923 1425-1433 NNS denotes proteins
T7924 1433-1434 . denotes .
T7925 1435-1443 VBN denotes Compared
T7926 1444-1448 IN denotes with
T7927 1449-1452 DT denotes the
T7928 1453-1462 JJ denotes wild-type
T7929 1463-1470 NN denotes protein
T7930 1470-1471 , denotes ,
T7931 1472-1475 DT denotes the
T7932 1476-1481 NNP denotes S209A
T7933 1482-1490 NN denotes mutation
T7934 1491-1498 VBD denotes reduced
T7935 1499-1503 NNP denotes IKKβ
T7936 1504-1512 VBD denotes mediated
T7937 1513-1517 JJ denotes RPS3
T7938 1518-1533 NN denotes phosphorylation
T7939 1534-1535 -LRB- denotes (
T7940 1535-1539 NNP denotes Fig.
T7941 1540-1542 CD denotes 4c
T7942 1542-1543 -RRB- denotes )
T7943 1543-1544 . denotes .
T7944 1545-1550 EX denotes There
T7945 1551-1556 MD denotes might
T7946 1557-1559 VB denotes be
T7947 1560-1571 JJ denotes alternative
T7948 1572-1587 NN denotes phosphorylation
T7949 1588-1592 NN denotes site
T7950 1592-1593 -LRB- denotes (
T7951 1593-1594 PRP denotes s
T7952 1594-1595 -RRB- denotes )
T7953 1596-1601 IN denotes under
T7954 1602-1607 DT denotes these
T7955 1608-1618 NNS denotes conditions
T7956 1619-1624 VBN denotes given
T7957 1625-1631 JJ denotes modest
T7958 1632-1640 JJ denotes residual
T7959 1641-1655 VBN denotes phosphorylated
T7960 1656-1660 NNP denotes RPS3
T7961 1661-1662 -LRB- denotes (
T7962 1662-1666 NNP denotes Fig.
T7963 1667-1669 CD denotes 4c
T7964 1669-1670 -RRB- denotes )
T7965 1670-1671 . denotes .
T7966 1672-1676 CD denotes RPS3
T7967 1677-1681 CD denotes S209
T7968 1682-1686 VBZ denotes does
T7969 1687-1690 RB denotes not
T7970 1691-1695 VB denotes fall
T7971 1696-1702 IN denotes within
T7972 1703-1704 DT denotes a
T7973 1705-1717 JJ denotes conventional
T7974 1718-1721 NNP denotes IKK
T7975 1722-1733 NN denotes recognition
T7976 1734-1739 NN denotes motif
T7977 1739-1740 , denotes ,
T7978 1741-1744 CC denotes but
T7979 1745-1751 RB denotes rather
T7980 1752-1759 VBZ denotes resides
T7981 1760-1762 IN denotes in
T7982 1763-1764 DT denotes a
T7983 1765-1773 NN denotes sequence
T7984 1774-1779 NN denotes motif
T7985 1780-1781 -LRB- denotes (
T7986 1781-1791 NNP denotes XXXpS/TXXE
T7987 1791-1792 -RRB- denotes )
T7988 1792-1793 , denotes ,
T7989 1794-1805 RB denotes potentially
T7990 1806-1816 VBN denotes recognized
T7991 1817-1819 IN denotes by
T7992 1820-1826 NN denotes casein
T7993 1827-1833 NN denotes kinase
T7994 1834-1836 NNP denotes II
T7995 1837-1838 -LRB- denotes (
T7996 1838-1841 NNP denotes CK2
T7997 1841-1842 -RRB- denotes )
T7998 1842-1843 . denotes .
T7999 1844-1852 IN denotes Although
T8000 1853-1857 NNP denotes IKKβ
T8001 1858-1864 NN denotes kinase
T8002 1865-1868 MD denotes can
T8003 1869-1876 VB denotes display
T8004 1877-1878 DT denotes a
T8005 1879-1887 JJ denotes CK2-like
T8006 1888-1903 NN denotes phosphorylation
T8007 1904-1917 NNS denotes specificity29
T8008 1917-1918 , denotes ,
T8009 1919-1921 DT denotes no
T8010 1922-1925 NN denotes CK2
T8011 1926-1933 NN denotes protein
T8012 1934-1937 VBD denotes was
T8013 1938-1948 JJ denotes detectable
T8014 1949-1951 IN denotes in
T8015 1952-1955 PRP$ denotes our
T8016 1956-1967 JJ denotes recombinant
T8017 1968-1971 NNP denotes IKK
T8018 1972-1980 NNS denotes proteins
T8019 1981-1982 -LRB- denotes (
T8020 1982-1995 NNP denotes Supplementary
T8021 1996-2000 NNP denotes Fig.
T8022 2001-2002 CD denotes 6
T8023 2002-2003 -RRB- denotes )
T8024 2003-2004 . denotes .
T8025 2005-2009 RB denotes Thus
T8026 2009-2010 , denotes ,
T8027 2011-2015 NNP denotes RPS3
T8028 2016-2020 NNP denotes S209
T8029 2021-2036 NN denotes phosphorylation
T8030 2037-2040 VBD denotes was
T8031 2041-2044 JJ denotes due
T8032 2045-2047 TO denotes to
T8033 2048-2051 DT denotes the
T8034 2052-2061 JJ denotes alternate
T8035 2062-2073 NN denotes specificity
T8036 2074-2076 IN denotes of
T8037 2077-2080 DT denotes the
T8038 2081-2085 NNP denotes IKKβ
T8039 2086-2092 NN denotes kinase
T8040 2093-2099 RB denotes rather
T8041 2100-2104 IN denotes than
T8042 2105-2108 DT denotes any
T8043 2109-2114 VBP denotes trace
T8044 2115-2121 NN denotes amount
T8045 2122-2124 IN denotes of
T8046 2125-2128 CD denotes CK2
T8047 2129-2134 VBN denotes bound
T8048 2135-2137 TO denotes to
T8049 2138-2142 NNS denotes IKKs
T8050 2142-2143 . denotes .
T8051 2144-2146 TO denotes To
T8052 2147-2156 VB denotes determine
T8053 2157-2164 IN denotes whether
T8054 2165-2169 NNP denotes S209
T8055 2170-2172 VBZ denotes is
T8056 2173-2176 DT denotes the
T8057 2177-2185 JJ denotes critical
T8058 2186-2190 NN denotes site
T8059 2191-2193 IN denotes at
T8060 2194-2199 WDT denotes which
T8061 2200-2204 NNP denotes IKKβ
T8062 2205-2219 VBZ denotes phosphorylates
T8063 2220-2224 NNP denotes RPS3
T8064 2225-2227 IN denotes in
T8065 2228-2234 VBG denotes living
T8066 2235-2240 NNS denotes cells
T8067 2240-2241 , denotes ,
T8068 2242-2244 PRP denotes we
T8069 2245-2256 VBD denotes transfected
T8070 2257-2260 DT denotes the
T8071 2261-2270 JJ denotes wild-type
T8072 2271-2273 CC denotes or
T8073 2274-2279 JJ denotes S209A
T8074 2280-2286 JJ denotes mutant
T8075 2287-2296 NN denotes Flag-RPS3
T8076 2297-2302 RB denotes alone
T8077 2302-2303 , denotes ,
T8078 2304-2306 CC denotes or
T8079 2307-2315 RB denotes together
T8080 2316-2320 IN denotes with
T8081 2321-2325 NNP denotes IKKβ
T8082 2326-2330 IN denotes into
T8083 2331-2336 NNS denotes cells
T8084 2336-2337 . denotes .
T8085 2338-2344 RB denotes Indeed
T8086 2344-2345 , denotes ,
T8087 2346-2348 PRP denotes we
T8088 2349-2357 VBD denotes observed
T8089 2358-2362 IN denotes that
T8090 2363-2377 VBG denotes overexpressing
T8091 2378-2382 NNP denotes IKKβ
T8092 2383-2391 JJ denotes enhanced
T8093 2392-2401 NN denotes Flag-RPS3
T8094 2402-2417 NN denotes phosphorylation
T8095 2417-2418 , denotes ,
T8096 2419-2422 CC denotes but
T8097 2423-2438 NN denotes phosphorylation
T8098 2439-2442 VBD denotes was
T8099 2443-2454 RB denotes effectively
T8100 2455-2465 VBN denotes eliminated
T8101 2466-2468 IN denotes by
T8102 2469-2476 JJ denotes alanine
T8103 2477-2489 NN denotes substitution
T8104 2490-2500 VBG denotes indicating
T8105 2501-2505 IN denotes that
T8106 2506-2510 CD denotes S209
T8107 2511-2513 VBZ denotes is
T8108 2514-2517 DT denotes the
T8109 2518-2529 JJ denotes predominant
T8110 2530-2536 NN denotes target
T8111 2537-2541 NN denotes site
T8112 2542-2545 IN denotes for
T8113 2546-2550 NNP denotes IKKβ
T8114 2551-2566 NN denotes phosphorylation
T8115 2567-2568 -LRB- denotes (
T8116 2568-2572 NNP denotes Fig.
T8117 2573-2575 CD denotes 4d
T8118 2575-2576 -RRB- denotes )
T8119 2576-2577 . denotes .
T8120 2578-2580 PRP denotes We
T8121 2581-2585 JJ denotes next
T8122 2586-2595 VBD denotes generated
T8123 2596-2597 DT denotes a
T8124 2598-2610 JJ denotes phospho-S209
T8125 2611-2615 NN denotes RPS3
T8126 2616-2624 NN denotes antibody
T8127 2625-2628 CC denotes and
T8128 2629-2638 VBD denotes confirmed
T8129 2639-2643 IN denotes that
T8130 2644-2654 JJ denotes endogenous
T8131 2655-2659 NN denotes RPS3
T8132 2660-2663 VBD denotes was
T8133 2664-2678 VBN denotes phosphorylated
T8134 2679-2681 IN denotes at
T8135 2682-2686 CD denotes S209
T8136 2687-2689 IN denotes in
T8137 2690-2691 DT denotes a
T8138 2692-2706 JJ denotes time-dependent
T8139 2707-2713 NN denotes manner
T8140 2714-2718 IN denotes upon
T8141 2719-2722 NNP denotes TNF
T8142 2723-2734 NN denotes stimulation
T8143 2735-2736 -LRB- denotes (
T8144 2736-2740 NNP denotes Fig.
T8145 2741-2743 CD denotes 4e
T8146 2743-2744 -RRB- denotes )
T8147 2744-2745 . denotes .
T8148 2746-2750 RB denotes Thus
T8149 2750-2751 , denotes ,
T8150 2752-2755 DT denotes the
T8151 2756-2760 NNP denotes RPS3
T8152 2761-2771 NNP denotes C-terminal
T8153 2772-2776 NN denotes tail
T8154 2777-2788 RB denotes potentially
T8155 2789-2797 VBZ denotes contains
T8156 2798-2800 DT denotes an
T8157 2801-2810 JJ denotes important
T8158 2811-2821 JJ denotes regulatory
T8159 2822-2826 NN denotes site
T8160 2826-2827 . denotes .
R6125 T7671 T7672 nsubj IKKβ,phosphorylates
R6126 T7672 T7672 ROOT phosphorylates,phosphorylates
R6127 T7673 T7672 dobj RPS3,phosphorylates
R6128 T7674 T7672 prep at,phosphorylates
R6129 T7675 T7674 pobj serine,at
R6130 T7676 T7675 nummod 209,serine
R6131 T7677 T7679 mark Although,defined
R6132 T7678 T7679 advmod originally,defined
R6133 T7679 T7689 advcl defined,phosphorylates
R6134 T7680 T7679 prep as,defined
R6135 T7681 T7682 det the,kinase
R6136 T7682 T7680 pobj kinase,as
R6137 T7683 T7684 nsubj that,phosphorylates
R6138 T7684 T7682 relcl phosphorylates,kinase
R6139 T7685 T7684 dobj IκB19,phosphorylates
R6140 T7686 T7689 punct ",",phosphorylates
R6141 T7687 T7689 nsubj IKKβ,phosphorylates
R6142 T7688 T7689 advmod also,phosphorylates
R6143 T7689 T7689 ROOT phosphorylates,phosphorylates
R6144 T7690 T7691 amod unrelated,substrates
R6145 T7691 T7689 dobj substrates,phosphorylates
R6146 T7692 T7691 prep including,substrates
R6147 T7693 T7692 pobj 14-3-3β,including
R6148 T7694 T7693 cc and,14-3-3β
R6149 T7695 T7693 conj Bcl10,14-3-3β
R6150 T7696 T7693 punct ",",14-3-3β
R6151 T7697 T7698 nsubj which,lack
R6152 T7698 T7693 relcl lack,14-3-3β
R6153 T7699 T7702 det the,motif
R6154 T7700 T7702 compound IKK,motif
R6155 T7701 T7702 compound consensus,motif
R6156 T7702 T7698 dobj motif,lack
R6157 T7703 T7704 punct (,DpSGYXpS/T
R6158 T7704 T7702 appos DpSGYXpS/T,motif
R6159 T7705 T7704 punct ),DpSGYXpS/T
R6160 T7706 T7702 appos 28,motif
R6161 T7707 T7689 punct .,phosphorylates
R6162 T7708 T7710 nsubj We,hypothesized
R6163 T7709 T7710 advmod therefore,hypothesized
R6164 T7710 T7710 ROOT hypothesized,hypothesized
R6165 T7711 T7715 mark that,phosphorylate
R6166 T7712 T7715 nsubj IKKβ,phosphorylate
R6167 T7713 T7715 aux could,phosphorylate
R6168 T7714 T7715 advmod directly,phosphorylate
R6169 T7715 T7710 ccomp phosphorylate,hypothesized
R6170 T7716 T7715 dobj RPS3,phosphorylate
R6171 T7717 T7710 punct .,hypothesized
R6172 T7718 T7731 prep By,observed
R6173 T7719 T7731 prep in,observed
R6174 T7720 T7722 amod vitro,assays
R6175 T7721 T7722 compound kinase,assays
R6176 T7722 T7719 pobj assays,in
R6177 T7723 T7722 acl using,assays
R6178 T7724 T7725 amod recombinant,IKK
R6179 T7725 T7728 nmod IKK,proteins
R6180 T7726 T7725 cc and,IKK
R6181 T7727 T7725 conj RPS3,IKK
R6182 T7728 T7723 dobj proteins,using
R6183 T7729 T7731 punct ",",observed
R6184 T7730 T7731 nsubj we,observed
R6185 T7731 T7731 ROOT observed,observed
R6186 T7732 T7733 amod strong,incorporation
R6187 T7733 T7731 dobj incorporation,observed
R6188 T7734 T7733 prep of,incorporation
R6189 T7735 T7734 pobj 32P,of
R6190 T7736 T7731 prep in,observed
R6191 T7737 T7738 compound autophosphorylatd,IKKα
R6192 T7738 T7745 nmod IKKα,lanes
R6193 T7739 T7738 cc and,IKKα
R6194 T7740 T7738 conj IKKβ,IKKα
R6195 T7741 T7742 punct (,Fig.
R6196 T7742 T7740 appos Fig.,IKKβ
R6197 T7743 T7742 nummod 4a,Fig.
R6198 T7744 T7740 punct ",",IKKβ
R6199 T7745 T7736 pobj lanes,in
R6200 T7746 T7731 advcl 2-7,observed
R6201 T7747 T7746 punct ),2-7
R6202 T7748 T7750 advmod as,as
R6203 T7749 T7750 advmod well,as
R6204 T7750 T7746 cc as,2-7
R6205 T7751 T7752 compound phosporylated,GST-IκBα
R6206 T7752 T7752 ROOT GST-IκBα,GST-IκBα
R6207 T7753 T7752 punct (,GST-IκBα
R6208 T7754 T7752 appos 1-54,GST-IκBα
R6209 T7755 T7752 punct ),GST-IκBα
R6210 T7756 T7752 punct (,GST-IκBα
R6211 T7757 T7758 compound Supplementary,Fig.
R6212 T7758 T7752 appos Fig.,GST-IκBα
R6213 T7759 T7758 nummod 4,Fig.
R6214 T7760 T7752 punct ),GST-IκBα
R6215 T7761 T7752 punct ",",GST-IκBα
R6216 T7762 T7731 cc but,observed
R6217 T7763 T7766 neg not,protein
R6218 T7764 T7766 det the,protein
R6219 T7765 T7766 compound GST,protein
R6220 T7766 T7772 nsubj protein,lanes
R6221 T7767 T7766 advmod alone,protein
R6222 T7768 T7766 punct (,protein
R6223 T7769 T7770 compound Fig.,4a
R6224 T7770 T7766 appos 4a,protein
R6225 T7771 T7770 punct ",",4a
R6226 T7772 T7731 conj lanes,observed
R6227 T7773 T7776 nmod 3,)
R6228 T7774 T7773 cc and,3
R6229 T7775 T7773 conj 6,3
R6230 T7776 T7772 punct ),lanes
R6231 T7777 T7772 punct ",",lanes
R6232 T7778 T7784 advmod when,used
R6233 T7779 T7780 preconj either,IKKα
R6234 T7780 T7784 nsubjpass IKKα,used
R6235 T7781 T7780 cc or,IKKα
R6236 T7782 T7780 conj IKKβ,IKKα
R6237 T7783 T7784 auxpass was,used
R6238 T7784 T7772 advcl used,lanes
R6239 T7785 T7731 punct .,observed
R6240 T7786 T7787 nsubj We,discovered
R6241 T7787 T7787 ROOT discovered,discovered
R6242 T7788 T7792 mark that,phosphorylated
R6243 T7789 T7792 nsubjpass GST-RPS3,phosphorylated
R6244 T7790 T7792 aux could,phosphorylated
R6245 T7791 T7792 auxpass be,phosphorylated
R6246 T7792 T7787 ccomp phosphorylated,discovered
R6247 T7793 T7792 agent by,phosphorylated
R6248 T7794 T7793 pobj IKKβ,by
R6249 T7795 T7792 punct ",",phosphorylated
R6250 T7796 T7792 cc but,phosphorylated
R6251 T7797 T7798 neg not,IKKα
R6252 T7798 T7806 nsubj IKKα,compare
R6253 T7799 T7798 punct ",",IKKα
R6254 T7800 T7798 prep in,IKKα
R6255 T7801 T7800 amod vitro,in
R6256 T7802 T7798 punct (,IKKα
R6257 T7803 T7798 conj Fig.,IKKα
R6258 T7804 T7803 nummod 4a,Fig.
R6259 T7805 T7798 punct ",",IKKα
R6260 T7806 T7792 conj compare,phosphorylated
R6261 T7807 T7806 dobj lanes,compare
R6262 T7808 T7807 nummod 4,lanes
R6263 T7809 T7808 cc and,4
R6264 T7810 T7808 conj 7,4
R6265 T7811 T7806 punct ),compare
R6266 T7812 T7787 punct .,discovered
R6267 T7813 T7814 aux To,identify
R6268 T7814 T7823 advcl identify,phosphorylated
R6269 T7815 T7819 det the,residue
R6270 T7816 T7819 amod RPS3,residue
R6271 T7817 T7819 amod amino,residue
R6272 T7818 T7819 compound acid,residue
R6273 T7819 T7814 dobj residue,identify
R6274 T7820 T7819 punct (,residue
R6275 T7821 T7819 appos s,residue
R6276 T7822 T7819 punct ),residue
R6277 T7823 T7828 advcl phosphorylated,performed
R6278 T7824 T7823 agent by,phosphorylated
R6279 T7825 T7824 pobj IKKβ,by
R6280 T7826 T7828 punct ",",performed
R6281 T7827 T7828 nsubj we,performed
R6282 T7828 T7828 ROOT performed,performed
R6283 T7829 T7833 amod liquid,analyses
R6284 T7830 T7833 nmod chromatography-tandem,analyses
R6285 T7831 T7833 nmod mass,analyses
R6286 T7832 T7833 compound spectrometry,analyses
R6287 T7833 T7828 dobj analyses,performed
R6288 T7834 T7833 acl using,analyses
R6289 T7835 T7834 prep in,using
R6290 T7836 T7835 pobj vitro,in
R6291 T7837 T7838 amod phosphorylated,RPS3
R6292 T7838 T7834 dobj RPS3,using
R6293 T7839 T7828 punct .,performed
R6294 T7840 T7841 det The,results
R6295 T7841 T7842 nsubj results,indicated
R6296 T7842 T7842 ROOT indicated,indicated
R6297 T7843 T7845 mark that,phosphorylated
R6298 T7844 T7845 nsubj IKKβ,phosphorylated
R6299 T7845 T7842 ccomp phosphorylated,indicated
R6300 T7846 T7845 dobj S209,phosphorylated
R6301 T7847 T7846 punct ",",S209
R6302 T7848 T7846 acl located,S209
R6303 T7849 T7848 prep in,located
R6304 T7850 T7852 det the,C-terminus
R6305 T7851 T7852 compound RPS3,C-terminus
R6306 T7852 T7849 pobj C-terminus,in
R6307 T7853 T7852 punct (,C-terminus
R6308 T7854 T7852 appos Fig.,C-terminus
R6309 T7855 T7854 nummod 4b,Fig.
R6310 T7856 T7852 punct ),C-terminus
R6311 T7857 T7842 punct .,indicated
R6312 T7858 T7862 nummod RPS3,alignment
R6313 T7859 T7862 compound amino,alignment
R6314 T7860 T7861 compound acid,sequence
R6315 T7861 T7862 compound sequence,alignment
R6316 T7862 T7863 nsubj alignment,revealed
R6317 T7863 T7863 ROOT revealed,revealed
R6318 T7864 T7867 mark that,conserved
R6319 T7865 T7867 nsubjpass S209,conserved
R6320 T7866 T7867 auxpass is,conserved
R6321 T7867 T7863 ccomp conserved,revealed
R6322 T7868 T7867 prep in,conserved
R6323 T7869 T7870 amod many,species
R6324 T7870 T7868 pobj species,in
R6325 T7871 T7870 prep throughout,species
R6326 T7872 T7871 pobj phylogeny,throughout
R6327 T7873 T7867 prep with,conserved
R6328 T7874 T7875 det the,exception
R6329 T7875 T7873 pobj exception,with
R6330 T7876 T7875 prep of,exception
R6331 T7877 T7878 compound Caenorhabditis,elegans
R6332 T7878 T7876 pobj elegans,of
R6333 T7879 T7878 cc and,elegans
R6334 T7880 T7878 conj Schizosaccharomyces,elegans
R6335 T7881 T7878 conj pombe,elegans
R6336 T7882 T7881 punct ",",pombe
R6337 T7883 T7884 nummod two,organisms
R6338 T7884 T7878 appos organisms,elegans
R6339 T7885 T7888 nsubj that,possess
R6340 T7886 T7888 aux do,possess
R6341 T7887 T7888 neg not,possess
R6342 T7888 T7884 relcl possess,organisms
R6343 T7889 T7892 det the,pathway
R6344 T7890 T7892 amod NF-κB,pathway
R6345 T7891 T7892 compound signal,pathway
R6346 T7892 T7888 dobj pathway,possess
R6347 T7893 T7892 punct (,pathway
R6348 T7894 T7895 compound Supplementary,Fig.
R6349 T7895 T7892 appos Fig.,pathway
R6350 T7896 T7895 nummod 5,Fig.
R6351 T7897 T7892 punct ),pathway
R6352 T7898 T7863 punct .,revealed
R6353 T7899 T7900 aux To,verify
R6354 T7900 T7910 advcl verify,performed
R6355 T7901 T7900 advmod biochemically,verify
R6356 T7902 T7904 mark that,is
R6357 T7903 T7904 nsubj S209,is
R6358 T7904 T7901 ccomp is,biochemically
R6359 T7905 T7907 det an,substrate
R6360 T7906 T7907 amod IKKβ,substrate
R6361 T7907 T7904 attr substrate,is
R6362 T7908 T7910 punct ",",performed
R6363 T7909 T7910 nsubj we,performed
R6364 T7910 T7910 ROOT performed,performed
R6365 T7911 T7910 dobj 32P-labeling,performed
R6366 T7912 T7910 prep in,performed
R6367 T7913 T7915 amod vitro,assays
R6368 T7914 T7915 compound kinase,assays
R6369 T7915 T7912 pobj assays,in
R6370 T7916 T7915 prep with,assays
R6371 T7917 T7923 amod recombinant,proteins
R6372 T7918 T7923 amod wild-type,proteins
R6373 T7919 T7918 cc or,wild-type
R6374 T7920 T7918 conj S209A,wild-type
R6375 T7921 T7923 amod mutant,proteins
R6376 T7922 T7923 compound RPS3,proteins
R6377 T7923 T7916 pobj proteins,with
R6378 T7924 T7910 punct .,performed
R6379 T7925 T7934 prep Compared,reduced
R6380 T7926 T7925 prep with,Compared
R6381 T7927 T7929 det the,protein
R6382 T7928 T7929 amod wild-type,protein
R6383 T7929 T7926 pobj protein,with
R6384 T7930 T7934 punct ",",reduced
R6385 T7931 T7933 det the,mutation
R6386 T7932 T7933 compound S209A,mutation
R6387 T7933 T7934 nsubj mutation,reduced
R6388 T7934 T7934 ROOT reduced,reduced
R6389 T7935 T7934 dobj IKKβ,reduced
R6390 T7936 T7934 conj mediated,reduced
R6391 T7937 T7938 amod RPS3,phosphorylation
R6392 T7938 T7936 dobj phosphorylation,mediated
R6393 T7939 T7940 punct (,Fig.
R6394 T7940 T7938 appos Fig.,phosphorylation
R6395 T7941 T7940 nummod 4c,Fig.
R6396 T7942 T7938 punct ),phosphorylation
R6397 T7943 T7934 punct .,reduced
R6398 T7944 T7946 expl There,be
R6399 T7945 T7946 aux might,be
R6400 T7946 T7946 ROOT be,be
R6401 T7947 T7949 amod alternative,site
R6402 T7948 T7949 compound phosphorylation,site
R6403 T7949 T7946 attr site,be
R6404 T7950 T7949 punct (,site
R6405 T7951 T7949 appos s,site
R6406 T7952 T7949 punct ),site
R6407 T7953 T7946 prep under,be
R6408 T7954 T7955 det these,conditions
R6409 T7955 T7953 pobj conditions,under
R6410 T7956 T7946 prep given,be
R6411 T7957 T7960 amod modest,RPS3
R6412 T7958 T7960 amod residual,RPS3
R6413 T7959 T7960 amod phosphorylated,RPS3
R6414 T7960 T7956 pobj RPS3,given
R6415 T7961 T7960 punct (,RPS3
R6416 T7962 T7960 appos Fig.,RPS3
R6417 T7963 T7962 nummod 4c,Fig.
R6418 T7964 T7960 punct ),RPS3
R6419 T7965 T7946 punct .,be
R6420 T7966 T7967 nummod RPS3,S209
R6421 T7967 T7970 nsubj S209,fall
R6422 T7968 T7970 aux does,fall
R6423 T7969 T7970 neg not,fall
R6424 T7970 T7970 ROOT fall,fall
R6425 T7971 T7970 prep within,fall
R6426 T7972 T7976 det a,motif
R6427 T7973 T7976 amod conventional,motif
R6428 T7974 T7976 compound IKK,motif
R6429 T7975 T7976 compound recognition,motif
R6430 T7976 T7971 pobj motif,within
R6431 T7977 T7970 punct ",",fall
R6432 T7978 T7970 cc but,fall
R6433 T7979 T7980 advmod rather,resides
R6434 T7980 T7970 conj resides,fall
R6435 T7981 T7980 prep in,resides
R6436 T7982 T7984 det a,motif
R6437 T7983 T7984 compound sequence,motif
R6438 T7984 T7981 pobj motif,in
R6439 T7985 T7986 punct (,XXXpS/TXXE
R6440 T7986 T7984 appos XXXpS/TXXE,motif
R6441 T7987 T7986 punct ),XXXpS/TXXE
R6442 T7988 T7980 punct ",",resides
R6443 T7989 T7990 advmod potentially,recognized
R6444 T7990 T7970 conj recognized,fall
R6445 T7991 T7990 agent by,recognized
R6446 T7992 T7994 amod casein,II
R6447 T7993 T7994 compound kinase,II
R6448 T7994 T7991 pobj II,by
R6449 T7995 T7994 punct (,II
R6450 T7996 T7994 appos CK2,II
R6451 T7997 T7994 punct ),II
R6452 T7998 T7970 punct .,fall
R6453 T7999 T8003 mark Although,display
R6454 T8000 T8001 compound IKKβ,kinase
R6455 T8001 T8003 nsubj kinase,display
R6456 T8002 T8003 aux can,display
R6457 T8003 T8012 advcl display,was
R6458 T8004 T8007 det a,specificity29
R6459 T8005 T8007 nummod CK2-like,specificity29
R6460 T8006 T8007 compound phosphorylation,specificity29
R6461 T8007 T8003 dobj specificity29,display
R6462 T8008 T8012 punct ",",was
R6463 T8009 T8011 det no,protein
R6501 T8047 T8044 acl bound,amount
R6502 T8048 T8047 prep to,bound
R6503 T8049 T8048 pobj IKKs,to
R6504 T8050 T8030 punct .,was
R6505 T8051 T8052 aux To,determine
R6506 T8052 T8069 advcl determine,transfected
R6507 T8053 T8055 mark whether,is
R6508 T8054 T8055 nsubj S209,is
R6509 T8055 T8052 ccomp is,determine
R6510 T8056 T8058 det the,site
R6511 T8057 T8058 amod critical,site
R6512 T8058 T8055 attr site,is
R6513 T8059 T8062 prep at,phosphorylates
R6514 T8060 T8059 pobj which,at
R6515 T8061 T8062 nsubj IKKβ,phosphorylates
R6516 T8062 T8058 relcl phosphorylates,site
R6517 T8063 T8062 dobj RPS3,phosphorylates
R6518 T8064 T8062 prep in,phosphorylates
R6519 T8065 T8066 amod living,cells
R6520 T8066 T8064 pobj cells,in
R6521 T8067 T8069 punct ",",transfected
R6522 T8068 T8069 nsubj we,transfected
R6523 T8069 T8069 ROOT transfected,transfected
R6524 T8070 T8075 det the,Flag-RPS3
R6525 T8071 T8075 amod wild-type,Flag-RPS3
R6526 T8072 T8071 cc or,wild-type
R6527 T8073 T8071 conj S209A,wild-type
R6528 T8074 T8075 amod mutant,Flag-RPS3
R6529 T8075 T8069 dobj Flag-RPS3,transfected
R6530 T8076 T8069 advmod alone,transfected
R6531 T8077 T8069 punct ",",transfected
R6532 T8078 T8069 cc or,transfected
R6533 T8079 T8080 advmod together,with
R6534 T8080 T8069 conj with,transfected
R6535 T8081 T8080 pobj IKKβ,with
R6536 T8082 T8080 conj into,with
R6537 T8083 T8082 pobj cells,into
R6538 T8084 T8069 punct .,transfected
R6539 T8085 T8088 advmod Indeed,observed
R6540 T8086 T8088 punct ",",observed
R6541 T8087 T8088 nsubj we,observed
R6560 T8106 T8107 nsubj S209,is
R6561 T8107 T8104 ccomp is,indicating
R6562 T8108 T8111 det the,site
R6563 T8109 T8111 amod predominant,site
R6564 T8110 T8111 compound target,site
R6565 T8111 T8107 attr site,is
R6566 T8112 T8111 prep for,site
R6567 T8113 T8114 compound IKKβ,phosphorylation
R6568 T8114 T8112 pobj phosphorylation,for
R6569 T8115 T8116 punct (,Fig.
R6570 T8116 T8114 appos Fig.,phosphorylation
R6571 T8117 T8116 nummod 4d,Fig.
R6572 T8118 T8100 punct ),eliminated
R6573 T8119 T8088 punct .,observed
R6574 T8120 T8122 nsubj We,generated
R6575 T8121 T8122 advmod next,generated
R6576 T8122 T8122 ROOT generated,generated
R6577 T8123 T8126 det a,antibody
R6578 T8124 T8126 amod phospho-S209,antibody
R6579 T8125 T8126 compound RPS3,antibody
R6580 T8126 T8122 dobj antibody,generated
R6581 T8127 T8122 cc and,generated
R6582 T8128 T8122 conj confirmed,generated
R6583 T8129 T8133 mark that,phosphorylated
R6584 T8130 T8131 amod endogenous,RPS3
R6585 T8131 T8133 nsubjpass RPS3,phosphorylated
R6586 T8132 T8133 auxpass was,phosphorylated
R6587 T8133 T8128 ccomp phosphorylated,confirmed
R6588 T8134 T8133 prep at,phosphorylated
R6589 T8135 T8134 pobj S209,at
R6590 T8136 T8133 prep in,phosphorylated
R6591 T8137 T8139 det a,manner
R6592 T8138 T8139 amod time-dependent,manner
R6593 T8139 T8136 pobj manner,in
R6594 T8140 T8139 prep upon,manner
R6595 T8141 T8142 compound TNF,stimulation
R6596 T8142 T8140 pobj stimulation,upon
R6597 T8143 T8133 punct (,phosphorylated
R6598 T8144 T8133 dep Fig.,phosphorylated
R6599 T8145 T8144 nummod 4e,Fig.
R6600 T8146 T8133 punct ),phosphorylated
R6601 T8147 T8122 punct .,generated
R6602 T8148 T8155 advmod Thus,contains
R6603 T8149 T8155 punct ",",contains
R6604 T8150 T8155 advmod the,contains
R6605 T8151 T8155 nsubj RPS3,contains
R6606 T8152 T8155 nsubj C-terminal,contains
R6607 T8153 T8155 nsubj tail,contains
R6608 T8154 T8155 advmod potentially,contains
R6609 T8155 T8155 ROOT contains,contains
R6610 T8156 T8159 det an,site
R6611 T8157 T8159 amod important,site
R6612 T8158 T8159 amod regulatory,site
R6613 T8159 T8155 dobj site,contains
R6614 T8160 T8155 punct .,contains
R6464 T8010 T8011 compound CK2,protein
R6465 T8011 T8012 nsubj protein,was
R6466 T8012 T8012 ROOT was,was
R6467 T8013 T8012 acomp detectable,was
R6468 T8014 T8013 prep in,detectable
R6469 T8015 T8018 poss our,proteins
R6470 T8016 T8018 amod recombinant,proteins
R6471 T8017 T8018 compound IKK,proteins
R6472 T8018 T8014 pobj proteins,in
R6473 T8019 T8021 punct (,Fig.
R6474 T8020 T8021 compound Supplementary,Fig.
R6475 T8021 T8013 appos Fig.,detectable
R6476 T8022 T8021 nummod 6,Fig.
R6477 T8023 T8021 punct ),Fig.
R6478 T8024 T8012 punct .,was
R6479 T8025 T8030 advmod Thus,was
R6480 T8026 T8030 punct ",",was
R6481 T8027 T8029 compound RPS3,phosphorylation
R6482 T8028 T8029 compound S209,phosphorylation
R6483 T8029 T8030 nsubj phosphorylation,was
R6484 T8030 T8030 ROOT was,was
R6485 T8031 T8030 acomp due,was
R6486 T8032 T8031 prep to,due
R6487 T8033 T8035 det the,specificity
R6488 T8034 T8035 amod alternate,specificity
R6489 T8035 T8032 pobj specificity,to
R6490 T8036 T8035 prep of,specificity
R6491 T8037 T8039 det the,kinase
R6492 T8038 T8039 compound IKKβ,kinase
R6493 T8039 T8036 pobj kinase,of
R6494 T8040 T8041 advmod rather,than
R6495 T8041 T8039 cc than,kinase
R6496 T8042 T8044 det any,amount
R6497 T8043 T8044 compound trace,amount
R6498 T8044 T8031 pobj amount,due
R6499 T8045 T8044 prep of,amount
R6500 T8046 T8045 pobj CK2,of
R6542 T8088 T8088 ROOT observed,observed
R6543 T8089 T8100 mark that,eliminated
R6544 T8090 T8100 nsubjpass overexpressing,eliminated
R6545 T8091 T8094 nmod IKKβ,phosphorylation
R6546 T8092 T8094 amod enhanced,phosphorylation
R6547 T8093 T8094 compound Flag-RPS3,phosphorylation
R6548 T8094 T8090 dobj phosphorylation,overexpressing
R6549 T8095 T8090 punct ",",overexpressing
R6550 T8096 T8090 cc but,overexpressing
R6551 T8097 T8100 nsubjpass phosphorylation,eliminated
R6552 T8098 T8100 auxpass was,eliminated
R6553 T8099 T8100 advmod effectively,eliminated
R6554 T8100 T8088 ccomp eliminated,observed
R6555 T8101 T8100 agent by,eliminated
R6556 T8102 T8103 amod alanine,substitution
R6557 T8103 T8101 pobj substitution,by
R6558 T8104 T8100 advcl indicating,eliminated
R6559 T8105 T8107 mark that,is

UBERON-AE

Id Subject Object Predicate Lexical cue
T7049 1193-1202 http://purl.obolibrary.org/obo/UBERON_0000062 denotes organisms
T7050 2772-2776 http://purl.obolibrary.org/obo/UBERON_0002415 denotes tail

GO-BP

Id Subject Object Predicate Lexical cue
T8269 198-201 http://purl.obolibrary.org/obo/GO_0008384 denotes IKK
T8270 349-352 http://purl.obolibrary.org/obo/GO_0008384 denotes IKK
T8271 1718-1721 http://purl.obolibrary.org/obo/GO_0008384 denotes IKK
T8272 1968-1971 http://purl.obolibrary.org/obo/GO_0008384 denotes IKK
T8273 1233-1239 http://purl.obolibrary.org/obo/GO_0023052 denotes signal
T8274 1233-1247 http://purl.obolibrary.org/obo/GO_0007165 denotes signal pathway
T8275 1518-1533 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T8276 1572-1587 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T8277 1888-1903 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T8278 2021-2036 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T8279 2402-2417 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T8280 2423-2438 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T8281 2551-2566 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation

GO-MF

Id Subject Object Predicate Lexical cue
T8282 198-201 http://purl.obolibrary.org/obo/GO_0008384 denotes IKK
T8283 349-352 http://purl.obolibrary.org/obo/GO_0008384 denotes IKK
T8284 1718-1721 http://purl.obolibrary.org/obo/GO_0008384 denotes IKK
T8285 1968-1971 http://purl.obolibrary.org/obo/GO_0008384 denotes IKK
T8286 2616-2624 http://purl.obolibrary.org/obo/GO_0003823 denotes antibody

GO-CC

Id Subject Object Predicate Lexical cue
T8287 2235-2240 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T8288 2331-2336 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T8289 2616-2624 http://purl.obolibrary.org/obo/GO_0019815 denotes antibody
T8290 2616-2624 http://purl.obolibrary.org/obo/GO_0042571 denotes antibody

sentences

Id Subject Object Predicate Lexical cue
T7141 0-38 Sentence denotes IKKβ phosphorylates RPS3 at serine 209
T7142 39-233 Sentence denotes Although originally defined as the kinase that phosphorylates IκB19, IKKβ also phosphorylates unrelated substrates including 14-3-3β and Bcl10, which lack the IKK consensus motif (DpSGYXpS/T)28.
T7143 234-304 Sentence denotes We therefore hypothesized that IKKβ could directly phosphorylate RPS3.
T7144 305-623 Sentence denotes By in vitro kinase assays using recombinant IKK and RPS3 proteins, we observed strong incorporation of 32P in autophosphorylatd IKKα and IKKβ (Fig. 4a, lanes 2-7) as well as phosporylated GST-IκBα (1-54) (Supplementary Fig. 4), but not the GST protein alone (Fig. 4a, lanes 3 and 6), when either IKKα or IKKβ was used.
T7145 624-741 Sentence denotes We discovered that GST-RPS3 could be phosphorylated by IKKβ, but not IKKα, in vitro (Fig. 4a, compare lanes 4 and 7).
T7146 742-913 Sentence denotes To identify the RPS3 amino acid residue(s) phosphorylated by IKKβ, we performed liquid chromatography-tandem mass spectrometry analyses using in vitro phosphorylated RPS3.
T7147 914-1008 Sentence denotes The results indicated that IKKβ phosphorylated S209, located in the RPS3 C-terminus (Fig. 4b).
T7148 1009-1271 Sentence denotes RPS3 amino acid sequence alignment revealed that S209 is conserved in many species throughout phylogeny with the exception of Caenorhabditis elegans and Schizosaccharomyces pombe, two organisms that do not possess the NF-κB signal pathway (Supplementary Fig. 5).
T7149 1272-1434 Sentence denotes To verify biochemically that S209 is an IKKβ substrate, we performed 32P-labeling in vitro kinase assays with recombinant wild-type or S209A mutant RPS3 proteins.
T7150 1435-1544 Sentence denotes Compared with the wild-type protein, the S209A mutation reduced IKKβ–mediated RPS3 phosphorylation (Fig. 4c).
T7151 1545-1671 Sentence denotes There might be alternative phosphorylation site(s) under these conditions given modest residual phosphorylated RPS3 (Fig. 4c).
T7152 1672-1843 Sentence denotes RPS3 S209 does not fall within a conventional IKK recognition motif, but rather resides in a sequence motif (XXXpS/TXXE), potentially recognized by casein kinase II (CK2).
T7153 1844-2004 Sentence denotes Although IKKβ kinase can display a CK2-like phosphorylation specificity29, no CK2 protein was detectable in our recombinant IKK proteins (Supplementary Fig. 6).
T7154 2005-2143 Sentence denotes Thus, RPS3 S209 phosphorylation was due to the alternate specificity of the IKKβ kinase rather than any trace amount of CK2 bound to IKKs.
T7155 2144-2337 Sentence denotes To determine whether S209 is the critical site at which IKKβ phosphorylates RPS3 in living cells, we transfected the wild-type or S209A mutant Flag-RPS3 alone, or together with IKKβ into cells.
T7156 2338-2577 Sentence denotes Indeed, we observed that overexpressing IKKβ enhanced Flag-RPS3 phosphorylation, but phosphorylation was effectively eliminated by alanine substitution indicating that S209 is the predominant target site for IKKβ phosphorylation (Fig. 4d).
T7157 2578-2745 Sentence denotes We next generated a phospho-S209 RPS3 antibody and confirmed that endogenous RPS3 was phosphorylated at S209 in a time-dependent manner upon TNF stimulation (Fig. 4e).
T7158 2746-2827 Sentence denotes Thus, the RPS3 C-terminal tail potentially contains an important regulatory site.
T68 0-38 Sentence denotes IKKβ phosphorylates RPS3 at serine 209
T69 39-233 Sentence denotes Although originally defined as the kinase that phosphorylates IκB19, IKKβ also phosphorylates unrelated substrates including 14-3-3β and Bcl10, which lack the IKK consensus motif (DpSGYXpS/T)28.
T70 234-304 Sentence denotes We therefore hypothesized that IKKβ could directly phosphorylate RPS3.
T71 305-623 Sentence denotes By in vitro kinase assays using recombinant IKK and RPS3 proteins, we observed strong incorporation of 32P in autophosphorylatd IKKα and IKKβ (Fig. 4a, lanes 2-7) as well as phosporylated GST-IκBα (1-54) (Supplementary Fig. 4), but not the GST protein alone (Fig. 4a, lanes 3 and 6), when either IKKα or IKKβ was used.
T72 624-741 Sentence denotes We discovered that GST-RPS3 could be phosphorylated by IKKβ, but not IKKα, in vitro (Fig. 4a, compare lanes 4 and 7).
T73 742-913 Sentence denotes To identify the RPS3 amino acid residue(s) phosphorylated by IKKβ, we performed liquid chromatography-tandem mass spectrometry analyses using in vitro phosphorylated RPS3.
T74 914-1008 Sentence denotes The results indicated that IKKβ phosphorylated S209, located in the RPS3 C-terminus (Fig. 4b).
T75 1009-1271 Sentence denotes RPS3 amino acid sequence alignment revealed that S209 is conserved in many species throughout phylogeny with the exception of Caenorhabditis elegans and Schizosaccharomyces pombe, two organisms that do not possess the NF-κB signal pathway (Supplementary Fig. 5).
T76 1272-1434 Sentence denotes To verify biochemically that S209 is an IKKβ substrate, we performed 32P-labeling in vitro kinase assays with recombinant wild-type or S209A mutant RPS3 proteins.
T77 1435-1544 Sentence denotes Compared with the wild-type protein, the S209A mutation reduced IKKβ–mediated RPS3 phosphorylation (Fig. 4c).
T78 1545-1671 Sentence denotes There might be alternative phosphorylation site(s) under these conditions given modest residual phosphorylated RPS3 (Fig. 4c).
T79 1672-1843 Sentence denotes RPS3 S209 does not fall within a conventional IKK recognition motif, but rather resides in a sequence motif (XXXpS/TXXE), potentially recognized by casein kinase II (CK2).
T80 1844-2004 Sentence denotes Although IKKβ kinase can display a CK2-like phosphorylation specificity29, no CK2 protein was detectable in our recombinant IKK proteins (Supplementary Fig. 6).
T81 2005-2143 Sentence denotes Thus, RPS3 S209 phosphorylation was due to the alternate specificity of the IKKβ kinase rather than any trace amount of CK2 bound to IKKs.
T82 2144-2337 Sentence denotes To determine whether S209 is the critical site at which IKKβ phosphorylates RPS3 in living cells, we transfected the wild-type or S209A mutant Flag-RPS3 alone, or together with IKKβ into cells.
T83 2338-2577 Sentence denotes Indeed, we observed that overexpressing IKKβ enhanced Flag-RPS3 phosphorylation, but phosphorylation was effectively eliminated by alanine substitution indicating that S209 is the predominant target site for IKKβ phosphorylation (Fig. 4d).
T84 2578-2745 Sentence denotes We next generated a phospho-S209 RPS3 antibody and confirmed that endogenous RPS3 was phosphorylated at S209 in a time-dependent manner upon TNF stimulation (Fig. 4e).
T85 2746-2827 Sentence denotes Thus, the RPS3 C-terminal tail potentially contains an important regulatory site.

events-check-again

Id Subject Object Predicate Lexical cue Negation Speculation
T8531 0-4 Protein denotes IKKβ
T8532 5-19 Phosphorylation denotes phosphorylates
T8533 20-24 Protein denotes RPS3
T8534 28-38 Entity denotes serine 209
T8535 108-112 Protein denotes IKKβ
T8536 118-132 Phosphorylation denotes phosphorylates
T8537 118-132 Phosphorylation denotes phosphorylates
T8538 164-171 Protein denotes 14-3-3β
T8539 176-181 Protein denotes Bcl10
T8540 265-269 Protein denotes IKKβ
T8541 285-298 Phosphorylation denotes phosphorylate true
T8542 299-303 Protein denotes RPS3
T8543 357-361 Protein denotes RPS3
T8544 391-411 Phosphorylation denotes incorporation of 32P
T8545 391-411 Phosphorylation denotes incorporation of 32P
T8546 415-432 Phosphorylation denotes autophosphorylatd
T8547 415-432 Phosphorylation denotes autophosphorylatd
T8548 433-437 Protein denotes IKKα
T8549 442-446 Protein denotes IKKβ
T8550 479-492 Phosphorylation denotes phosporylated true
T8551 479-492 Phosphorylation denotes phosporylated true
T8552 493-501 Protein denotes GST-IκBα
T8553 545-548 Protein denotes GST
T8554 601-605 Protein denotes IKKα
T8555 609-613 Protein denotes IKKβ
T8556 643-651 Protein denotes GST-RPS3
T8557 661-675 Phosphorylation denotes phosphorylated true true
T8558 661-675 Phosphorylation denotes phosphorylated true
T8559 679-683 Protein denotes IKKβ
T8560 693-697 Protein denotes IKKα
T8561 758-762 Protein denotes RPS3
T8562 763-784 Entity denotes amino acid residue(s)
T8563 785-799 Phosphorylation denotes phosphorylated
T8564 803-807 Protein denotes IKKβ
T8565 893-907 Phosphorylation denotes phosphorylated
T8566 908-912 Protein denotes RPS3
T8567 941-945 Protein denotes IKKβ
T8568 946-960 Phosphorylation denotes phosphorylated
T8569 961-965 Entity denotes S209
T8570 982-986 Protein denotes RPS3
T8571 1009-1013 Protein denotes RPS3
T8572 1312-1316 Protein denotes IKKβ
T8573 1363-1369 Protein denotes kinase
T8574 1407-1412 Entity denotes S209A
T8575 1413-1419 Regulation denotes mutant
T8576 1420-1424 Protein denotes RPS3
T8577 1476-1481 Entity denotes S209A
T8578 1482-1490 Regulation denotes mutation
T8579 1491-1498 Negative_regulation denotes reduced
T8580 1499-1504 Protein denotes IKKβ–
T8581 1504-1512 Positive_regulation denotes mediated
T8582 1513-1517 Protein denotes RPS3
T8583 1518-1533 Phosphorylation denotes phosphorylation
T8584 1641-1655 Phosphorylation denotes phosphorylated
T8585 1656-1660 Protein denotes RPS3
T8586 1672-1676 Protein denotes RPS3
T8587 1765-1779 Entity denotes sequence motif
T8588 1806-1816 Binding denotes recognized
T8589 1853-1857 Protein denotes IKKβ
T8590 2011-2015 Protein denotes RPS3
T8591 2016-2020 Entity denotes S209
T8592 2021-2036 Phosphorylation denotes phosphorylation
T8593 2041-2044 Positive_regulation denotes due true
T8594 2081-2085 Protein denotes IKKβ
T8595 2165-2169 Entity denotes S209
T8596 2177-2185 Positive_regulation denotes critical true
T8597 2200-2204 Protein denotes IKKβ
T8598 2205-2219 Phosphorylation denotes phosphorylates
T8599 2220-2224 Protein denotes RPS3
T8600 2245-2256 Gene_expression denotes transfected
T8601 2245-2256 Gene_expression denotes transfected
T8602 2287-2296 Protein denotes Flag-RPS3
T8603 2321-2325 Protein denotes IKKβ
T8604 2363-2377 Positive_regulation denotes overexpressing
T8605 2378-2382 Protein denotes IKKβ
T8606 2383-2391 Positive_regulation denotes enhanced
T8607 2392-2401 Protein denotes Flag-RPS3
T8608 2402-2417 Phosphorylation denotes phosphorylation
T8609 2455-2465 Negative_regulation denotes eliminated
T8610 2469-2489 Regulation denotes alanine substitution
T8611 2506-2510 Entity denotes S209
T8612 2546-2550 Protein denotes IKKβ
T8613 2551-2566 Phosphorylation denotes phosphorylation
T8614 2598-2624 Protein denotes phospho-S209 RPS3 antibody
T8615 2655-2659 Protein denotes RPS3
T8616 2664-2678 Phosphorylation denotes phosphorylated
T8617 2682-2686 Entity denotes S209
T8618 2697-2706 Regulation denotes dependent
T8619 2714-2718 Positive_regulation denotes upon
T8620 2756-2760 Protein denotes RPS3
R6820 T8531 T8532 causeOf IKKβ,phosphorylates
R6821 T8534 T8532 themeOf serine 209,phosphorylates
R6822 T8534 T8533 partOf serine 209,RPS3
R6823 T8535 T8537 causeOf IKKβ,phosphorylates
R6824 T8535 T8536 causeOf IKKβ,phosphorylates
R6825 T8538 T8537 themeOf 14-3-3β,phosphorylates
R6826 T8539 T8536 themeOf Bcl10,phosphorylates
R6827 T8540 T8541 causeOf IKKβ,phosphorylate
R6828 T8542 T8541 themeOf RPS3,phosphorylate
R6829 T8548 T8544 themeOf IKKα,incorporation of 32P
R6830 T8548 T8547 themeOf IKKα,autophosphorylatd
R6831 T8549 T8545 themeOf IKKβ,incorporation of 32P
R6832 T8549 T8546 themeOf IKKβ,autophosphorylatd
R6833 T8552 T8550 themeOf GST-IκBα,phosporylated
R6834 T8553 T8551 themeOf GST,phosporylated
R6835 T8556 T8558 themeOf GST-RPS3,phosphorylated
R6836 T8556 T8557 themeOf GST-RPS3,phosphorylated
R6837 T8559 T8558 causeOf IKKβ,phosphorylated
R6838 T8560 T8557 causeOf IKKα,phosphorylated
R6839 T8562 T8563 themeOf amino acid residue(s),phosphorylated
R6840 T8562 T8561 partOf amino acid residue(s),RPS3
R6841 T8564 T8563 causeOf IKKβ,phosphorylated
R6842 T8566 T8565 themeOf RPS3,phosphorylated
R6843 T8567 T8568 causeOf IKKβ,phosphorylated
R6844 T8569 T8568 themeOf S209,phosphorylated
R6845 T8569 T8570 partOf S209,RPS3
R6846 T8574 T8575 themeOf S209A,mutant
R6847 T8574 T8576 partOf S209A,RPS3
R6848 T8577 T8578 themeOf S209A,mutation
R6849 T8577 T8582 partOf S209A,RPS3
R6850 T8578 T8579 causeOf mutation,reduced
R6851 T8580 T8581 causeOf IKKβ–,mediated
R6852 T8581 T8579 themeOf mediated,reduced
R6853 T8582 T8583 themeOf RPS3,phosphorylation
R6854 T8583 T8581 themeOf phosphorylation,mediated
R6855 T8585 T8584 themeOf RPS3,phosphorylated
R6856 T8587 T8588 themeOf sequence motif,recognized
R6857 T8587 T8586 partOf sequence motif,RPS3
R6858 T8591 T8592 themeOf S209,phosphorylation
R6859 T8591 T8590 partOf S209,RPS3
R6860 T8592 T8593 themeOf phosphorylation,due
R6861 T8594 T8593 causeOf IKKβ,due
R6862 T8595 T8596 causeOf S209,critical
R6863 T8595 T8599 partOf S209,RPS3
R6864 T8597 T8598 causeOf IKKβ,phosphorylates
R6865 T8598 T8596 themeOf phosphorylates,critical
R6866 T8599 T8598 themeOf RPS3,phosphorylates
R6867 T8602 T8600 themeOf Flag-RPS3,transfected
R6868 T8603 T8601 themeOf IKKβ,transfected
R6869 T8604 T8606 causeOf overexpressing,enhanced
R6870 T8605 T8604 themeOf IKKβ,overexpressing
R6871 T8607 T8608 themeOf Flag-RPS3,phosphorylation
R6872 T8608 T8606 themeOf phosphorylation,enhanced
R6873 T8608 T8609 themeOf phosphorylation,eliminated
R6874 T8610 T8609 causeOf alanine substitution,eliminated
R6875 T8611 T8610 themeOf S209,alanine substitution
R6876 T8611 T8607 partOf S209,Flag-RPS3
R6877 T8611 T8613 themeOf S209,phosphorylation
R6878 T8616 T8618 themeOf phosphorylated,dependent
R6879 T8617 T8616 themeOf S209,phosphorylated
R6880 T8617 T8615 partOf S209,RPS3
R6881 T8618 T8619 themeOf dependent,upon

bionlp-st-ge-2016-reference

Id Subject Object Predicate Lexical cue Negation Speculation
T7051 0-4 Protein denotes IKKβ
T7052 5-19 Phosphorylation denotes phosphorylates
T7053 20-24 Protein denotes RPS3
T7054 28-38 Entity denotes serine 209
T7055 108-112 Protein denotes IKKβ
T7056 118-132 Phosphorylation denotes phosphorylates
T7057 118-132 Phosphorylation denotes phosphorylates
T7058 164-171 Protein denotes 14-3-3β
T7059 176-181 Protein denotes Bcl10
T7060 265-269 Protein denotes IKKβ
T7061 285-298 Phosphorylation denotes phosphorylate true
T7062 299-303 Protein denotes RPS3
T7063 357-361 Protein denotes RPS3
T7064 391-411 Phosphorylation denotes incorporation of 32P
T7065 391-411 Phosphorylation denotes incorporation of 32P
T7066 415-432 Phosphorylation denotes autophosphorylatd
T7067 415-432 Phosphorylation denotes autophosphorylatd
T7068 433-437 Protein denotes IKKα
T7069 442-446 Protein denotes IKKβ
T7070 479-492 Phosphorylation denotes phosporylated true
T7071 479-492 Phosphorylation denotes phosporylated true
T7072 493-501 Protein denotes GST-IκBα
T7073 545-548 Protein denotes GST
T7074 601-605 Protein denotes IKKα
T7075 609-613 Protein denotes IKKβ
T7076 643-651 Protein denotes GST-RPS3
T7077 661-675 Phosphorylation denotes phosphorylated true true
T7078 661-675 Phosphorylation denotes phosphorylated true
T7079 679-683 Protein denotes IKKβ
T7080 693-697 Protein denotes IKKα
T7081 758-762 Protein denotes RPS3
T7082 763-784 Entity denotes amino acid residue(s)
T7083 785-799 Phosphorylation denotes phosphorylated
T7084 803-807 Protein denotes IKKβ
T7085 893-907 Phosphorylation denotes phosphorylated
T7086 908-912 Protein denotes RPS3
T7087 941-945 Protein denotes IKKβ
T7088 946-960 Phosphorylation denotes phosphorylated
T7089 961-965 Entity denotes S209
T7090 982-986 Protein denotes RPS3
T7091 1009-1013 Protein denotes RPS3
T7092 1312-1316 Protein denotes IKKβ
T7093 1363-1369 Protein denotes kinase
T7094 1407-1412 Entity denotes S209A
T7095 1413-1419 Regulation denotes mutant
T7096 1420-1424 Protein denotes RPS3
T7097 1476-1481 Entity denotes S209A
T7098 1482-1490 Regulation denotes mutation
T7099 1491-1498 Negative_regulation denotes reduced
T7100 1499-1504 Protein denotes IKKβ–
T7101 1504-1512 Positive_regulation denotes mediated
T7102 1513-1517 Protein denotes RPS3
T7103 1518-1533 Phosphorylation denotes phosphorylation
T7104 1641-1655 Phosphorylation denotes phosphorylated
T7105 1656-1660 Protein denotes RPS3
T7106 1672-1676 Protein denotes RPS3
T7107 1765-1779 Entity denotes sequence motif
T7108 1806-1816 Binding denotes recognized
T7109 1853-1857 Protein denotes IKKβ
T7110 2011-2015 Protein denotes RPS3
T7111 2016-2020 Entity denotes S209
T7112 2021-2036 Phosphorylation denotes phosphorylation
T7113 2041-2044 Positive_regulation denotes due true
T7114 2081-2085 Protein denotes IKKβ
T7115 2165-2169 Entity denotes S209
T7116 2177-2185 Positive_regulation denotes critical true
T7117 2200-2204 Protein denotes IKKβ
T7118 2205-2219 Phosphorylation denotes phosphorylates
T7119 2220-2224 Protein denotes RPS3
T7120 2245-2256 Gene_expression denotes transfected
T7121 2245-2256 Gene_expression denotes transfected
T7122 2287-2296 Protein denotes Flag-RPS3
T7123 2321-2325 Protein denotes IKKβ
T7124 2363-2377 Positive_regulation denotes overexpressing
T7125 2378-2382 Protein denotes IKKβ
T7126 2383-2391 Positive_regulation denotes enhanced
T7127 2392-2401 Protein denotes Flag-RPS3
T7128 2402-2417 Phosphorylation denotes phosphorylation
T7129 2455-2465 Negative_regulation denotes eliminated
T7130 2469-2489 Regulation denotes alanine substitution
T7131 2506-2510 Entity denotes S209
T7132 2546-2550 Protein denotes IKKβ
T7133 2551-2566 Phosphorylation denotes phosphorylation
T7134 2598-2624 Protein denotes phospho-S209 RPS3 antibody
T7135 2655-2659 Protein denotes RPS3
T7136 2664-2678 Phosphorylation denotes phosphorylated
T7137 2682-2686 Entity denotes S209
T7138 2697-2706 Regulation denotes dependent
T7139 2714-2718 Positive_regulation denotes upon
T7140 2756-2760 Protein denotes RPS3
R5588 T7051 T7052 causeOf IKKβ,phosphorylates
R5589 T7054 T7052 themeOf serine 209,phosphorylates
R5590 T7054 T7053 partOf serine 209,RPS3
R5591 T7055 T7057 causeOf IKKβ,phosphorylates
R5592 T7055 T7056 causeOf IKKβ,phosphorylates
R5593 T7058 T7057 themeOf 14-3-3β,phosphorylates
R5594 T7059 T7056 themeOf Bcl10,phosphorylates
R5595 T7060 T7061 causeOf IKKβ,phosphorylate
R5596 T7062 T7061 themeOf RPS3,phosphorylate
R5597 T7068 T7064 themeOf IKKα,incorporation of 32P
R5598 T7068 T7067 themeOf IKKα,autophosphorylatd
R5599 T7069 T7065 themeOf IKKβ,incorporation of 32P
R5600 T7069 T7066 themeOf IKKβ,autophosphorylatd
R5601 T7072 T7070 themeOf GST-IκBα,phosporylated
R5602 T7073 T7071 themeOf GST,phosporylated
R5603 T7076 T7078 themeOf GST-RPS3,phosphorylated
R5604 T7076 T7077 themeOf GST-RPS3,phosphorylated
R5605 T7079 T7078 causeOf IKKβ,phosphorylated
R5606 T7080 T7077 causeOf IKKα,phosphorylated
R5607 T7082 T7083 themeOf amino acid residue(s),phosphorylated
R5608 T7082 T7081 partOf amino acid residue(s),RPS3
R5609 T7084 T7083 causeOf IKKβ,phosphorylated
R5610 T7086 T7085 themeOf RPS3,phosphorylated
R5611 T7087 T7088 causeOf IKKβ,phosphorylated
R5612 T7089 T7088 themeOf S209,phosphorylated
R5613 T7089 T7090 partOf S209,RPS3
R5614 T7094 T7095 themeOf S209A,mutant
R5615 T7094 T7096 partOf S209A,RPS3
R5616 T7097 T7098 themeOf S209A,mutation
R5617 T7097 T7102 partOf S209A,RPS3
R5618 T7098 T7099 causeOf mutation,reduced
R5619 T7100 T7101 causeOf IKKβ–,mediated
R5620 T7101 T7099 themeOf mediated,reduced
R5621 T7102 T7103 themeOf RPS3,phosphorylation
R5622 T7103 T7101 themeOf phosphorylation,mediated
R5623 T7105 T7104 themeOf RPS3,phosphorylated
R5624 T7107 T7108 themeOf sequence motif,recognized
R5625 T7107 T7106 partOf sequence motif,RPS3
R5626 T7111 T7112 themeOf S209,phosphorylation
R5627 T7111 T7110 partOf S209,RPS3
R5628 T7112 T7113 themeOf phosphorylation,due
R5629 T7114 T7113 causeOf IKKβ,due
R5630 T7115 T7116 causeOf S209,critical
R5631 T7115 T7119 partOf S209,RPS3
R5632 T7117 T7118 causeOf IKKβ,phosphorylates
R5633 T7118 T7116 themeOf phosphorylates,critical
R5634 T7119 T7118 themeOf RPS3,phosphorylates
R5635 T7122 T7120 themeOf Flag-RPS3,transfected
R5636 T7123 T7121 themeOf IKKβ,transfected
R5637 T7124 T7126 causeOf overexpressing,enhanced
R5638 T7125 T7124 themeOf IKKβ,overexpressing
R5639 T7127 T7128 themeOf Flag-RPS3,phosphorylation
R5640 T7128 T7126 themeOf phosphorylation,enhanced
R5641 T7128 T7129 themeOf phosphorylation,eliminated
R5642 T7130 T7129 causeOf alanine substitution,eliminated
R5643 T7131 T7130 themeOf S209,alanine substitution
R5644 T7131 T7127 partOf S209,Flag-RPS3
R5645 T7131 T7133 themeOf S209,phosphorylation
R5646 T7136 T7138 themeOf phosphorylated,dependent
R5647 T7137 T7136 themeOf S209,phosphorylated
R5648 T7137 T7135 partOf S209,RPS3
R5649 T7138 T7139 themeOf dependent,upon

test2

Id Subject Object Predicate Lexical cue Negation Speculation
T6969 0-4 Protein denotes IKKβ
T6970 5-19 Phosphorylation denotes phosphorylates
T6971 20-24 Protein denotes RPS3
T6972 108-112 Protein denotes IKKβ true
T6973 118-132 Phosphorylation denotes phosphorylates
T6974 164-171 Protein denotes 14-3-3β
T6975 176-181 Protein denotes Bcl10
T6976 189-193 Negative_regulation denotes lack
T6977 265-269 Protein denotes IKKβ true
T6978 285-298 Phosphorylation denotes phosphorylate true
T6979 299-303 Protein denotes RPS3 true
T6980 357-361 Protein denotes RPS3 true true
T6981 415-432 Phosphorylation denotes autophosphorylatd
T6982 433-437 Protein denotes IKKα
T6983 442-446 Protein denotes IKKβ
T6984 479-492 Phosphorylation denotes phosporylated
T6985 493-501 Protein denotes GST-IκBα
T6986 545-548 Protein denotes GST
T6987 601-605 Protein denotes IKKα
T6988 609-613 Protein denotes IKKβ
T6989 643-651 Protein denotes GST-RPS3
T6990 661-675 Phosphorylation denotes phosphorylated
T6991 679-683 Protein denotes IKKβ
T6992 693-697 Protein denotes IKKα true
T6993 758-762 Protein denotes RPS3 true
T6994 763-783 Entity denotes amino acid residue(s
T6995 785-799 Phosphorylation denotes phosphorylated
T6996 803-807 Protein denotes IKKβ
T6997 893-907 Phosphorylation denotes phosphorylated
T6998 908-912 Protein denotes RPS3
T6999 941-945 Protein denotes IKKβ
T7000 946-960 Phosphorylation denotes phosphorylated
T7001 961-965 Entity denotes S209
T7002 982-986 Protein denotes RPS3
T7003 1009-1013 Protein denotes RPS3
T7004 1058-1062 Entity denotes S209
T7005 1301-1305 Entity denotes S209
T7006 1312-1316 Protein denotes IKKβ
T7007 1363-1369 Protein denotes kinase
T7008 1420-1424 Protein denotes RPS3
T7009 1491-1498 Negative_regulation denotes reduced
T7010 1499-1504 Protein denotes IKKβ–
T7011 1504-1512 Positive_regulation denotes mediated
T7012 1513-1517 Protein denotes RPS3
T7013 1518-1533 Phosphorylation denotes phosphorylation
T7014 1641-1655 Phosphorylation denotes phosphorylated
T7015 1656-1660 Protein denotes RPS3
T7016 1672-1676 Protein denotes RPS3
T7017 1677-1681 Entity denotes S209
T7018 1765-1779 Entity denotes sequence motif
T7019 1806-1816 Binding denotes recognized
T7020 1853-1857 Protein denotes IKKβ
T7021 2011-2015 Protein denotes RPS3
T7022 2016-2020 Entity denotes S209
T7023 2021-2036 Phosphorylation denotes phosphorylation
T7024 2041-2044 Positive_regulation denotes due
T7025 2081-2085 Protein denotes IKKβ
T7026 2129-2134 Binding denotes bound
T7027 2165-2169 Entity denotes S209
T7028 2200-2204 Protein denotes IKKβ
T7029 2205-2219 Phosphorylation denotes phosphorylates
T7030 2220-2224 Protein denotes RPS3
T7031 2287-2296 Protein denotes Flag-RPS3
T7032 2321-2325 Protein denotes IKKβ
T7033 2363-2377 Positive_regulation denotes overexpressing
T7034 2378-2382 Protein denotes IKKβ
T7035 2383-2391 Positive_regulation denotes enhanced
T7036 2392-2401 Protein denotes Flag-RPS3
T7037 2402-2417 Phosphorylation denotes phosphorylation
T7038 2423-2438 Phosphorylation denotes phosphorylation
T7039 2455-2465 Negative_regulation denotes eliminated
T7040 2506-2510 Entity denotes S209
T7041 2546-2550 Protein denotes IKKβ
T7042 2551-2566 Phosphorylation denotes phosphorylation
T7043 2598-2624 Protein denotes phospho-S209 RPS3 antibody
T7044 2655-2659 Protein denotes RPS3
T7045 2664-2678 Phosphorylation denotes phosphorylated
T7046 2682-2686 Entity denotes S209
T7047 2697-2706 Regulation denotes dependent
T7048 2756-2760 Protein denotes RPS3
R5542 T6969 T6970 causeOf IKKβ,phosphorylates
R5543 T6972 T6973 themeOf IKKβ,phosphorylates
R5544 T6974 T6973 themeOf 14-3-3β,phosphorylates
R5545 T6975 T6973 themeOf Bcl10,phosphorylates
R5546 T6979 T6978 themeOf RPS3,phosphorylate
R5547 T6982 T6981 themeOf IKKα,autophosphorylatd
R5548 T6983 T6981 themeOf IKKβ,autophosphorylatd
R5549 T6985 T6984 themeOf GST-IκBα,phosporylated
R5550 T6989 T6990 themeOf GST-RPS3,phosphorylated
R5551 T6991 T6990 causeOf IKKβ,phosphorylated
R5552 T6994 T6993 partOf amino acid residue(s,RPS3
R5553 T6996 T6995 causeOf IKKβ,phosphorylated
R5554 T6998 T6997 themeOf RPS3,phosphorylated
R5555 T6999 T7000 causeOf IKKβ,phosphorylated
R5556 T7001 T7000 themeOf S209,phosphorylated
R5557 T7010 T7011 causeOf IKKβ–,mediated
R5558 T7011 T7009 themeOf mediated,reduced
R5559 T7012 T7013 themeOf RPS3,phosphorylation
R5560 T7013 T7011 themeOf phosphorylation,mediated
R5561 T7015 T7014 themeOf RPS3,phosphorylated
R5562 T7016 T7019 themeOf RPS3,recognized
R5563 T7017 T7019 themeOf S209,recognized
R5564 T7017 T7016 partOf S209,RPS3
R5565 T7018 T7016 partOf sequence motif,RPS3
R5566 T7018 T7019 themeOf sequence motif,recognized
R5567 T7022 T7023 themeOf S209,phosphorylation
R5568 T7022 T7021 partOf S209,RPS3
R5569 T7023 T7024 themeOf phosphorylation,due
R5570 T7025 T7024 causeOf IKKβ,due
R5571 T7026 T7024 causeOf bound,due
R5572 T7027 T7030 partOf S209,RPS3
R5573 T7028 T7029 causeOf IKKβ,phosphorylates
R5574 T7030 T7029 themeOf RPS3,phosphorylates
R5575 T7033 T7035 causeOf overexpressing,enhanced
R5576 T7034 T7035 causeOf IKKβ,enhanced
R5577 T7034 T7033 themeOf IKKβ,overexpressing
R5578 T7036 T7037 themeOf Flag-RPS3,phosphorylation
R5579 T7037 T7035 themeOf phosphorylation,enhanced
R5580 T7037 T7039 themeOf phosphorylation,eliminated
R5581 T7038 T7039 themeOf phosphorylation,eliminated
R5582 T7040 T7039 causeOf S209,eliminated
R5583 T7040 T7042 themeOf S209,phosphorylation
R5584 T7040 T7036 partOf S209,Flag-RPS3
R5585 T7045 T7047 themeOf phosphorylated,dependent
R5586 T7046 T7045 themeOf S209,phosphorylated
R5587 T7046 T7044 partOf S209,RPS3