PMC:3062687 / 23994-28180
Annnotations
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T18781 | 11-15 | P23396 | denotes | RPS3 |
T18782 | 189-193 | P23396 | denotes | RPS3 |
T18783 | 279-283 | O14920 | denotes | IKKβ |
T18784 | 293-297 | P23396 | denotes | RPS3 |
T18785 | 455-459 | O14920 | denotes | IKKβ |
T18786 | 592-596 | P23396 | denotes | RPS3 |
T18787 | 722-726 | O14920 | denotes | IKKβ |
T18788 | 821-825 | O14920 | denotes | IKKβ |
T18789 | 856-860 | P23396 | denotes | RPS3 |
T18790 | 921-925 | P23396 | denotes | RPS3 |
T18791 | 1055-1058 | P21579 | denotes | p65 |
T18792 | 1055-1058 | Q04206 | denotes | p65 |
T18793 | 1150-1154 | O14920 | denotes | IKKβ |
T18794 | 1196-1200 | P23396 | denotes | RPS3 |
T18795 | 1252-1256 | O14920 | denotes | IKKβ |
T18796 | 1314-1318 | P23396 | denotes | RPS3 |
T18797 | 1384-1388 | P23396 | denotes | RPS3 |
T18798 | 1540-1544 | P23396 | denotes | RPS3 |
T18799 | 1693-1697 | O14920 | denotes | IKKβ |
T18800 | 1707-1711 | P23396 | denotes | RPS3 |
T18801 | 1837-1842 | P23396 | denotes | NleH1 |
T18802 | 1865-1869 | P23396 | denotes | RPS3 |
T18803 | 2003-2008 | P23396 | denotes | NleH1 |
T18804 | 2030-2034 | P23396 | denotes | RPS3 |
T18805 | 2173-2178 | P23396 | denotes | NleH1 |
T18806 | 2210-2214 | O14920 | denotes | IKKβ |
T18807 | 2260-2264 | O14920 | denotes | IKKβ |
T18808 | 2274-2278 | P23396 | denotes | RPS3 |
T18809 | 2430-2435 | P23396 | denotes | NleH1 |
T18810 | 2474-2478 | O14920 | denotes | IKKβ |
T18811 | 2745-2750 | P23396 | denotes | NleH1 |
T18812 | 2783-2787 | P23396 | denotes | RPS3 |
T18813 | 2917-2920 | P10145 | denotes | IL8 |
T18814 | 2925-2928 | P01375 | denotes | TNF |
T18815 | 2943-2948 | P23396 | denotes | NleH1 |
T18816 | 2970-2973 | P21579 | denotes | p65 |
T18817 | 2970-2973 | Q04206 | denotes | p65 |
T18818 | 3025-3028 | Q04206 | denotes | p65 |
T18819 | 3025-3028 | P21579 | denotes | p65 |
T18820 | 3043-3047 | P23396 | denotes | RPS3 |
T18821 | 3192-3196 | P23396 | denotes | RPS3 |
T18822 | 3235-3240 | P23396 | denotes | NleH1 |
T18823 | 3836-3840 | P23396 | denotes | RPS3 |
T18824 | 3859-3862 | Q04206 | denotes | p65 |
T18825 | 3859-3862 | P21579 | denotes | p65 |
T18826 | 4142-4146 | P23396 | denotes | RPS3 |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
21399639-18045535-74765178 | 118-119 | 18045535 | denotes | 6 |
21399639-18045535-74765178 | 118-119 | 18045535 | denotes | 6 |
21399639-17047224-74765179 | 576-578 | 17047224 | denotes | 40 |
21399639-17047224-74765179 | 576-578 | 17047224 | denotes | 40 |
21399639-16818647-74765180 | 1096-1098 | 16818647 | denotes | 41 |
21399639-16818647-74765180 | 1096-1098 | 16818647 | denotes | 41 |
21399639-10938077-74765180 | 1096-1098 | 10938077 | denotes | 41 |
21399639-10938077-74765180 | 1096-1098 | 10938077 | denotes | 41 |
21399639-15033982-74765180 | 1096-1098 | 15033982 | denotes | 41 |
21399639-15033982-74765180 | 1096-1098 | 15033982 | denotes | 41 |
21399639-20041225-74765181 | 1977-1978 | 20041225 | denotes | 9 |
21399639-20041225-74765181 | 1977-1978 | 20041225 | denotes | 9 |
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T18146 | 11-15 | NN | denotes | RPS3 |
T18148 | 20-30 | RB | denotes | previously |
T18149 | 31-43 | VB | denotes | demonstrated |
T18150 | 44-46 | TO | denotes | to |
T18151 | 47-55 | VB | denotes | function |
T18152 | 56-58 | IN | denotes | as |
T18153 | 59-61 | DT | denotes | an |
T18154 | 62-70 | JJ | denotes | integral |
T18155 | 71-78 | NN | denotes | subunit |
T18156 | 79-89 | VB | denotes | conferring |
T18157 | 90-95 | NN | denotes | NF-κB |
T18158 | 96-106 | JJ | denotes | regulatory |
T18159 | 107-119 | NN | denotes | specificity6 |
T18160 | 121-125 | RB | denotes | Here |
T18161 | 126-128 | PRP | denotes | we |
T18162 | 129-135 | VB | denotes | sought |
T18163 | 136-138 | TO | denotes | to |
T18164 | 139-148 | VB | denotes | elucidate |
T18165 | 149-152 | WRB | denotes | how |
T18166 | 153-158 | NN | denotes | NF-κB |
T18167 | 159-169 | NN | denotes | activation |
T18168 | 170-179 | NN | denotes | signaling |
T18169 | 180-188 | VB | denotes | triggers |
T18170 | 189-193 | NN | denotes | RPS3 |
T18171 | 194-196 | TO | denotes | to |
T18172 | 197-208 | VB | denotes | translocate |
T18173 | 209-212 | CC | denotes | and |
T18174 | 213-224 | VB | denotes | participate |
T18175 | 225-227 | IN | denotes | in |
T18176 | 228-233 | NN | denotes | NF-κB |
T18177 | 234-242 | NN | denotes | function |
T18178 | 243-245 | IN | denotes | in |
T18179 | 246-249 | DT | denotes | the |
T18180 | 250-257 | NN | denotes | nucleus |
T18181 | 259-261 | PRP | denotes | We |
T18182 | 262-273 | VB | denotes | demonstrate |
T18183 | 274-278 | IN | denotes | that |
T18184 | 279-292 | JJ | denotes | IKKβ-mediated |
T18185 | 293-297 | NN | denotes | RPS3 |
T18186 | 298-302 | NN | denotes | S209 |
T18187 | 303-318 | NN | denotes | phosphorylation |
T18188 | 319-329 | VB | denotes | represents |
T18189 | 330-331 | DT | denotes | a |
T18190 | 332-340 | JJ | denotes | critical |
T18191 | 341-352 | NN | denotes | determinant |
T18192 | 353-355 | IN | denotes | in |
T18193 | 356-365 | VB | denotes | governing |
T18194 | 366-369 | PRP-DOLLAR- | denotes | its |
T18195 | 370-377 | JJ | denotes | nuclear |
T18196 | 378-384 | NN | denotes | import |
T18197 | 385-389 | RB | denotes | thus |
T18198 | 390-399 | VB | denotes | unveiling |
T18199 | 400-401 | DT | denotes | a |
T18200 | 402-407 | JJ | denotes | novel |
T18201 | 408-417 | NN | denotes | mechanism |
T18202 | 418-424 | IN | denotes | behind |
T18203 | 425-430 | NN | denotes | NF-κB |
T18204 | 431-441 | JJ | denotes | regulatory |
T18205 | 442-453 | NN | denotes | specificity |
T18206 | 455-459 | NN | denotes | IKKβ |
T18207 | 460-462 | VB | denotes | is |
T18208 | 463-466 | DT | denotes | the |
T18209 | 467-472 | JJ | denotes | major |
T18210 | 473-479 | NN | denotes | kinase |
T18211 | 480-484 | WDT | denotes | that |
T18212 | 485-499 | VB | denotes | phosphorylates |
T18213 | 500-504 | NN | denotes | IκBs |
T18214 | 505-507 | IN | denotes | in |
T18215 | 508-511 | DT | denotes | the |
T18216 | 512-521 | JJ | denotes | classical |
T18217 | 522-527 | NN | denotes | NF-κB |
T18218 | 528-535 | NN | denotes | pathway |
T18219 | 535-536 | -COMMA- | denotes | , |
T18220 | 537-544 | VB | denotes | leading |
T18221 | 545-547 | TO | denotes | to |
T18222 | 548-553 | PRP-DOLLAR- | denotes | their |
T18223 | 554-564 | JJ | denotes | subsequent |
T18224 | 565-578 | NN | denotes | degradation40 |
T18225 | 580-590 | RB | denotes | Strikingly |
T18226 | 590-591 | -COMMA- | denotes | , |
T18227 | 592-596 | NN | denotes | RPS3 |
T18228 | 597-606 | VB | denotes | possesses |
T18229 | 607-610 | RB | denotes | not |
T18230 | 611-614 | DT | denotes | any |
T18231 | 615-624 | NN | denotes | consensus |
T18232 | 625-628 | NN | denotes | IKK |
T18233 | 629-634 | NN | denotes | motif |
T18234 | 634-635 | -COLON- | denotes | ; |
T18235 | 636-643 | RB | denotes | instead |
T18236 | 643-644 | -COMMA- | denotes | , |
T18237 | 645-649 | NN | denotes | S209 |
T18238 | 650-652 | VB | denotes | is |
T18239 | 653-661 | VB | denotes | centered |
T18240 | 662-664 | IN | denotes | in |
T18241 | 665-666 | DT | denotes | a |
T18242 | 667-676 | NN | denotes | consensus |
T18243 | 677-680 | NN | denotes | CK2 |
T18244 | 681-686 | NN | denotes | motif |
T18245 | 688-691 | DT | denotes | The |
T18246 | 692-698 | JJ | denotes | recent |
T18247 | 699-710 | NN | denotes | observation |
T18248 | 711-715 | IN | denotes | that |
T18249 | 716-721 | JJ | denotes | human |
T18250 | 722-726 | NN | denotes | IKKβ |
T18251 | 727-736 | VB | denotes | displayed |
T18252 | 737-745 | JJ | denotes | CK2-like |
T18253 | 746-761 | NN | denotes | phosphorylation |
T18254 | 762-775 | NN | denotes | specificity29 |
T18255 | 776-785 | NN | denotes | coincides |
T18256 | 786-790 | IN | denotes | with |
T18257 | 791-794 | PRP-DOLLAR- | denotes | our |
T18258 | 795-803 | NN | denotes | evidence |
T18259 | 804-808 | IN | denotes | that |
T18260 | 809-820 | JJ | denotes | recombinant |
T18261 | 821-825 | NN | denotes | IKKβ |
T18262 | 825-826 | -COMMA- | denotes | , |
T18263 | 827-830 | CC | denotes | but |
T18264 | 831-834 | RB | denotes | not |
T18265 | 835-839 | NN | denotes | IKKα |
T18266 | 839-840 | -COMMA- | denotes | , |
T18267 | 841-855 | VB | denotes | phosphorylated |
T18268 | 856-860 | NN | denotes | RPS3 |
T18269 | 862-864 | PRP | denotes | We |
T18270 | 865-870 | VB | denotes | found |
T18271 | 871-875 | DT | denotes | this |
T18272 | 876-891 | NN | denotes | phosphorylation |
T18273 | 892-894 | VB | denotes | is |
T18274 | 895-896 | DT | denotes | a |
T18275 | 897-905 | JJ | denotes | critical |
T18276 | 906-916 | NN | denotes | modulation |
T18277 | 917-920 | IN | denotes | for |
T18278 | 921-925 | NN | denotes | RPS3 |
T18279 | 926-933 | JJ | denotes | nuclear |
T18280 | 934-947 | NN | denotes | translocation |
T18281 | 948-949 | -LRB- | denotes | ( |
T18282 | 949-952 | IN | denotes | via |
T18283 | 953-963 | NN | denotes | importin-α |
T18284 | 963-964 | -RRB- | denotes | ) |
T18285 | 965-968 | CC | denotes | and |
T18286 | 969-979 | NN | denotes | engagement |
T18287 | 980-982 | IN | denotes | in |
T18288 | 983-991 | JJ | denotes | specific |
T18289 | 992-997 | NN | denotes | NF-κB |
T18290 | 998-1011 | NN | denotes | transcription |
T18291 | 1013-1016 | NN | denotes | CK2 |
T18292 | 1017-1020 | VB | denotes | was |
T18293 | 1021-1031 | RB | denotes | previously |
T18294 | 1032-1037 | VB | denotes | shown |
T18295 | 1038-1040 | TO | denotes | to |
T18296 | 1041-1054 | VB | denotes | phosphorylate |
T18297 | 1055-1058 | NN | denotes | p65 |
T18298 | 1059-1062 | CC | denotes | and |
T18299 | 1063-1065 | TO | denotes | to |
T18300 | 1066-1070 | VB | denotes | bind |
T18301 | 1071-1073 | TO | denotes | to |
T18302 | 1074-1077 | CC | denotes | and |
T18303 | 1078-1091 | VB | denotes | phosphorylate |
T18304 | 1092-1101 | NN | denotes | IKKβ41-43 |
T18305 | 1101-1102 | -COMMA- | denotes | , |
T18306 | 1103-1110 | RB | denotes | however |
T18307 | 1110-1111 | -COMMA- | denotes | , |
T18308 | 1112-1114 | PRP | denotes | we |
T18309 | 1115-1120 | VB | denotes | ruled |
T18310 | 1121-1124 | RP | denotes | out |
T18311 | 1125-1128 | DT | denotes | the |
T18312 | 1129-1140 | NN | denotes | possibility |
T18313 | 1141-1145 | IN | denotes | that |
T18314 | 1146-1149 | DT | denotes | the |
T18315 | 1150-1160 | JJ | denotes | IKKβ-bound |
T18316 | 1161-1164 | NN | denotes | CK2 |
T18317 | 1165-1170 | MD | denotes | could |
T18318 | 1171-1178 | VB | denotes | account |
T18319 | 1179-1182 | IN | denotes | for |
T18320 | 1183-1186 | DT | denotes | the |
T18321 | 1187-1195 | VB | denotes | observed |
T18322 | 1196-1200 | NN | denotes | RPS3 |
T18323 | 1201-1216 | NN | denotes | phosphorylation |
T18324 | 1217-1224 | IN | denotes | because |
T18325 | 1225-1227 | DT | denotes | no |
T18326 | 1228-1231 | NN | denotes | CK2 |
T18327 | 1232-1235 | VB | denotes | was |
T18328 | 1236-1244 | VB | denotes | detected |
T18329 | 1245-1247 | IN | denotes | in |
T18330 | 1248-1251 | DT | denotes | the |
T18331 | 1252-1256 | NN | denotes | IKKβ |
T18332 | 1257-1269 | NN | denotes | preparations |
T18333 | 1270-1274 | VB | denotes | used |
T18334 | 1275-1278 | IN | denotes | for |
T18335 | 1279-1282 | DT | denotes | the |
T18336 | 1283-1285 | FW | denotes | in |
T18337 | 1286-1291 | FW | denotes | vitro |
T18338 | 1292-1298 | NN | denotes | kinase |
T18339 | 1299-1304 | NN | denotes | assay |
T18340 | 1306-1313 | IN | denotes | Because |
T18341 | 1314-1318 | NN | denotes | RPS3 |
T18342 | 1319-1323 | RB | denotes | only |
T18343 | 1324-1331 | VB | denotes | harbors |
T18344 | 1332-1335 | DT | denotes | the |
T18345 | 1336-1339 | NN | denotes | CK2 |
T18346 | 1340-1345 | NN | denotes | motif |
T18347 | 1346-1349 | CC | denotes | and |
T18348 | 1350-1353 | RB | denotes | not |
T18349 | 1354-1355 | DT | denotes | a |
T18350 | 1356-1367 | JJ | denotes | traditional |
T18351 | 1368-1371 | NN | denotes | IKK |
T18352 | 1372-1377 | NN | denotes | motif |
T18353 | 1377-1378 | -COMMA- | denotes | , |
T18354 | 1379-1383 | DT | denotes | this |
T18355 | 1384-1388 | NN | denotes | RPS3 |
T18356 | 1389-1399 | JJ | denotes | regulatory |
T18357 | 1400-1408 | NN | denotes | function |
T18358 | 1409-1414 | MD | denotes | could |
T18359 | 1415-1422 | VB | denotes | explain |
T18360 | 1423-1426 | WRB | denotes | why |
T18361 | 1427-1430 | NN | denotes | IKK |
T18362 | 1431-1438 | VB | denotes | harbors |
T18363 | 1439-1442 | DT | denotes | the |
T18364 | 1443-1454 | JJ | denotes | alternative |
T18365 | 1455-1464 | NN | denotes | substrate |
T18366 | 1465-1480 | NN | denotes | phosphorylation |
T18367 | 1481-1491 | NN | denotes | capability |
T18368 | 1493-1497 | RB | denotes | More |
T18369 | 1498-1509 | RB | denotes | importantly |
T18370 | 1509-1510 | -COMMA- | denotes | , |
T18371 | 1511-1514 | PRP-DOLLAR- | denotes | our |
T18372 | 1515-1520 | NN | denotes | study |
T18373 | 1521-1524 | VB | denotes | has |
T18374 | 1525-1535 | VB | denotes | elucidated |
T18375 | 1536-1539 | WRB | denotes | how |
T18376 | 1540-1544 | NN | denotes | RPS3 |
T18377 | 1545-1547 | VB | denotes | is |
T18378 | 1548-1561 | RB | denotes | biochemically |
T18379 | 1562-1572 | VB | denotes | integrated |
T18380 | 1573-1577 | IN | denotes | into |
T18381 | 1578-1583 | NN | denotes | NF-κB |
T18382 | 1584-1594 | NN | denotes | activation |
T18383 | 1595-1604 | NN | denotes | signaling |
T18384 | 1605-1607 | IN | denotes | in |
T18385 | 1608-1609 | DT | denotes | a |
T18386 | 1610-1616 | NN | denotes | manner |
T18387 | 1617-1621 | WDT | denotes | that |
T18388 | 1622-1624 | VB | denotes | is |
T18389 | 1625-1632 | JJ | denotes | pivotal |
T18390 | 1633-1636 | IN | denotes | for |
T18391 | 1637-1640 | DT | denotes | the |
T18392 | 1641-1653 | NN | denotes | pathogenesis |
T18393 | 1654-1656 | IN | denotes | of |
T18394 | 1657-1666 | JJ | denotes | foodborne |
T18395 | 1667-1675 | NN | denotes | pathogen |
T18396 | 1676-1678 | FW | denotes | E. |
T18397 | 1679-1683 | FW | denotes | coli |
T18398 | 1684-1688 | NN | denotes | O157 |
T18399 | 1688-1689 | -COLON- | denotes | : |
T18400 | 1689-1691 | NN | denotes | H7 |
T18401 | 1693-1706 | JJ | denotes | IKKβ-mediated |
T18402 | 1707-1711 | NN | denotes | RPS3 |
T18403 | 1712-1716 | NN | denotes | S209 |
T18404 | 1717-1732 | NN | denotes | phosphorylation |
T18405 | 1733-1735 | VB | denotes | is |
T18406 | 1736-1737 | DT | denotes | a |
T18407 | 1738-1746 | JJ | denotes | critical |
T18408 | 1747-1753 | NN | denotes | target |
T18409 | 1754-1763 | VB | denotes | modulated |
T18410 | 1764-1766 | IN | denotes | by |
T18411 | 1767-1771 | DT | denotes | this |
T18412 | 1772-1780 | NN | denotes | pathogen |
T18413 | 1781-1783 | TO | denotes | to |
T18414 | 1784-1791 | VB | denotes | subvert |
T18415 | 1792-1796 | NN | denotes | host |
T18416 | 1797-1802 | NN | denotes | NF-κB |
T18417 | 1803-1812 | NN | denotes | signaling |
T18418 | 1814-1817 | DT | denotes | The |
T18419 | 1818-1827 | JJ | denotes | bacterial |
T18420 | 1828-1836 | NN | denotes | effector |
T18421 | 1837-1842 | NN | denotes | NleH1 |
T18422 | 1843-1855 | RB | denotes | specifically |
T18423 | 1856-1861 | VB | denotes | binds |
T18424 | 1862-1864 | TO | denotes | to |
T18425 | 1865-1869 | NN | denotes | RPS3 |
T18426 | 1870-1874 | RB | denotes | once |
T18427 | 1875-1883 | VB | denotes | injected |
T18428 | 1884-1888 | IN | denotes | into |
T18429 | 1889-1893 | NN | denotes | host |
T18430 | 1894-1899 | NN | denotes | cells |
T18431 | 1900-1903 | CC | denotes | and |
T18432 | 1904-1914 | RB | denotes | profoundly |
T18433 | 1915-1925 | VB | denotes | suppresses |
T18434 | 1926-1931 | NN | denotes | NF-κB |
T18435 | 1932-1935 | CC | denotes | and |
T18436 | 1936-1939 | PRP-DOLLAR- | denotes | its |
T18437 | 1940-1949 | JJ | denotes | attendant |
T18439 | 1961-1967 | JJ | denotes | immune |
T18440 | 1968-1978 | NN | denotes | responses9 |
T18441 | 1980-1983 | PRP-DOLLAR- | denotes | Our |
T18442 | 1984-1988 | NN | denotes | data |
T18443 | 1989-1992 | RB | denotes | now |
T18444 | 1993-1997 | VB | denotes | show |
T18445 | 1998-2002 | IN | denotes | that |
T18446 | 2003-2008 | NN | denotes | NleH1 |
T18447 | 2009-2020 | RB | denotes | selectively |
T18448 | 2021-2029 | VB | denotes | inhibits |
T18449 | 2030-2034 | NN | denotes | RPS3 |
T18450 | 2035-2050 | NN | denotes | phosphorylation |
T18451 | 2050-2051 | -COMMA- | denotes | , |
T18452 | 2052-2056 | RB | denotes | thus |
T18453 | 2057-2066 | VB | denotes | retarding |
T18454 | 2067-2070 | PRP-DOLLAR- | denotes | its |
T18455 | 2071-2078 | JJ | denotes | nuclear |
T18456 | 2079-2092 | NN | denotes | translocation |
T18457 | 2093-2096 | CC | denotes | and |
T18458 | 2097-2107 | JJ | denotes | subsequent |
T18459 | 2108-2113 | NN | denotes | NF-κB |
T18460 | 2114-2122 | NN | denotes | function |
T18461 | 2122-2123 | -COMMA- | denotes | , |
T18462 | 2124-2131 | IN | denotes | without |
T18463 | 2132-2140 | VB | denotes | altering |
T18464 | 2141-2146 | JJ | denotes | other |
T18465 | 2147-2152 | NN | denotes | NF-κB |
T18466 | 2153-2162 | NN | denotes | signaling |
T18467 | 2164-2172 | IN | denotes | Although |
T18468 | 2173-2178 | NN | denotes | NleH1 |
T18469 | 2179-2182 | VB | denotes | did |
T18470 | 2183-2186 | RB | denotes | not |
T18471 | 2187-2195 | RB | denotes | directly |
T18472 | 2196-2209 | VB | denotes | phosphorylate |
T18473 | 2210-2214 | NN | denotes | IKKβ |
T18474 | 2214-2215 | -COMMA- | denotes | , |
T18475 | 2216-2219 | PRP-DOLLAR- | denotes | its |
T18476 | 2220-2226 | NN | denotes | kinase |
T18477 | 2227-2235 | NN | denotes | activity |
T18478 | 2236-2239 | VB | denotes | was |
T18479 | 2240-2248 | VB | denotes | required |
T18480 | 2249-2251 | TO | denotes | to |
T18481 | 2252-2259 | VB | denotes | inhibit |
T18482 | 2260-2273 | JJ | denotes | IKKβ-mediated |
T18483 | 2274-2278 | NN | denotes | RPS3 |
T18484 | 2279-2283 | NN | denotes | S209 |
T18485 | 2284-2299 | NN | denotes | phosphorylation |
T18486 | 2301-2305 | JJ | denotes | Many |
T18487 | 2306-2314 | NN | denotes | bacteria |
T18488 | 2315-2324 | NN | denotes | pathogens |
T18489 | 2325-2329 | VB | denotes | have |
T18490 | 2330-2338 | NN | denotes | products |
T18491 | 2339-2343 | WDT | denotes | that |
T18492 | 2344-2350 | VB | denotes | target |
T18493 | 2351-2354 | JJ | denotes | key |
T18494 | 2355-2362 | NN | denotes | kinases |
T18495 | 2363-2365 | TO | denotes | to |
T18496 | 2366-2376 | VB | denotes | inactivate |
T18497 | 2377-2381 | PRP | denotes | them |
T18498 | 2382-2384 | IN | denotes | in |
T18499 | 2385-2389 | NN | denotes | host |
T18500 | 2390-2395 | NN | denotes | cells |
T18501 | 2395-2396 | -COMMA- | denotes | , |
T18502 | 2397-2404 | IN | denotes | whereas |
T18503 | 2405-2407 | FW | denotes | E. |
T18504 | 2408-2412 | FW | denotes | coli |
T18505 | 2413-2417 | NN | denotes | O157 |
T18506 | 2417-2418 | -COLON- | denotes | : |
T18507 | 2418-2420 | NN | denotes | H7 |
T18508 | 2421-2429 | VB | denotes | employed |
T18509 | 2430-2435 | NN | denotes | NleH1 |
T18510 | 2436-2438 | TO | denotes | to |
T18511 | 2439-2444 | VB | denotes | steer |
T18512 | 2445-2448 | DT | denotes | the |
T18513 | 2449-2458 | NN | denotes | substrate |
T18514 | 2459-2470 | NN | denotes | specificity |
T18515 | 2471-2473 | IN | denotes | of |
T18516 | 2474-2478 | NN | denotes | IKKβ |
T18517 | 2479-2483 | RB | denotes | thus |
T18518 | 2484-2496 | RB | denotes | specifically |
T18519 | 2497-2508 | JJ | denotes | fine-tuning |
T18520 | 2509-2513 | NN | denotes | host |
T18521 | 2514-2519 | NN | denotes | NF-κB |
T18522 | 2520-2529 | NN | denotes | signaling |
T18523 | 2531-2535 | DT | denotes | This |
T18524 | 2536-2541 | MD | denotes | could |
T18525 | 2542-2551 | VB | denotes | represent |
T18526 | 2552-2553 | DT | denotes | a |
T18527 | 2554-2559 | JJ | denotes | novel |
T18528 | 2560-2568 | NN | denotes | strategy |
T18529 | 2569-2571 | TO | denotes | to |
T18530 | 2572-2581 | VB | denotes | fine-tune |
T18531 | 2582-2586 | NN | denotes | host |
T18532 | 2587-2592 | NN | denotes | NF-κB |
T18533 | 2593-2602 | NN | denotes | signaling |
T18534 | 2603-2607 | WDT | denotes | that |
T18535 | 2608-2613 | MD | denotes | could |
T18536 | 2614-2616 | VB | denotes | be |
T18537 | 2617-2623 | VB | denotes | shared |
T18538 | 2624-2626 | IN | denotes | by |
T18539 | 2627-2632 | JJ | denotes | other |
T18540 | 2633-2642 | NN | denotes | pathogens |
T18541 | 2644-2649 | DT | denotes | These |
T18542 | 2650-2654 | NN | denotes | data |
T18543 | 2655-2662 | VB | denotes | provide |
T18544 | 2663-2666 | JJ | denotes | new |
T18545 | 2667-2675 | NN | denotes | insights |
T18546 | 2676-2680 | IN | denotes | into |
T18547 | 2681-2684 | DT | denotes | the |
T18548 | 2685-2691 | RB | denotes | poorly |
T18549 | 2692-2702 | VB | denotes | understood |
T18550 | 2703-2709 | NN | denotes | action |
T18551 | 2710-2719 | NN | denotes | mechanism |
T18552 | 2720-2723 | IN | denotes | for |
T18553 | 2724-2728 | JJ | denotes | most |
T18554 | 2729-2733 | NN | denotes | T3SS |
T18555 | 2734-2743 | NN | denotes | effectors |
T18556 | 2745-2750 | NN | denotes | NleH1 |
T18557 | 2751-2761 | VB | denotes | attenuates |
T18558 | 2762-2765 | DT | denotes | the |
T18559 | 2766-2779 | NN | denotes | transcription |
T18560 | 2780-2782 | IN | denotes | of |
T18561 | 2783-2797 | JJ | denotes | RPS3-dependent |
T18562 | 2797-2798 | -COMMA- | denotes | , |
T18563 | 2799-2802 | CC | denotes | but |
T18564 | 2803-2806 | RB | denotes | not |
T18565 | 2807-2810 | DT | denotes | all |
T18566 | 2810-2811 | -COMMA- | denotes | , |
T18567 | 2812-2817 | NN | denotes | NF-κB |
T18568 | 2818-2824 | NN | denotes | target |
T18569 | 2825-2830 | NN | denotes | genes |
T18570 | 2830-2831 | -COMMA- | denotes | , |
T18571 | 2832-2834 | IN | denotes | in |
T18572 | 2835-2845 | JJ | denotes | particular |
T18573 | 2846-2851 | DT | denotes | those |
T18574 | 2852-2857 | NN | denotes | genes |
T18575 | 2858-2868 | VB | denotes | associated |
T18576 | 2869-2873 | IN | denotes | with |
T18577 | 2874-2879 | JJ | denotes | acute |
T18578 | 2880-2895 | JJ | denotes | proinflammatory |
T18579 | 2896-2905 | NN | denotes | responses |
T18580 | 2905-2906 | -COMMA- | denotes | , |
T18581 | 2907-2916 | VB | denotes | including |
T18582 | 2917-2920 | NN | denotes | IL8 |
T18583 | 2921-2924 | CC | denotes | and |
T18584 | 2925-2928 | NN | denotes | TNF |
T18585 | 2930-2932 | IN | denotes | In |
T18586 | 2933-2941 | NN | denotes | contrast |
T18587 | 2941-2942 | -COMMA- | denotes | , |
T18588 | 2943-2948 | NN | denotes | NleH1 |
T18589 | 2949-2953 | VB | denotes | does |
T18590 | 2954-2957 | RB | denotes | not |
T18591 | 2958-2963 | VB | denotes | block |
T18592 | 2964-2969 | NN | denotes | NF-κB |
T18593 | 2970-2973 | NN | denotes | p65 |
T18594 | 2974-2981 | JJ | denotes | nuclear |
T18595 | 2982-2995 | NN | denotes | translocation |
T18596 | 2995-2996 | -COMMA- | denotes | , |
T18597 | 2997-3002 | WDT | denotes | which |
T18598 | 3003-3011 | VB | denotes | suggests |
T18599 | 3012-3016 | IN | denotes | that |
T18600 | 3017-3024 | JJ | denotes | certain |
T18601 | 3025-3038 | JJ | denotes | p65-dependent |
T18602 | 3039-3042 | CC | denotes | but |
T18603 | 3043-3059 | JJ | denotes | RPS3-independent |
T18604 | 3060-3065 | NN | denotes | NF-κB |
T18605 | 3066-3072 | NN | denotes | target |
T18606 | 3073-3078 | NN | denotes | genes |
T18607 | 3079-3084 | MD | denotes | might |
T18608 | 3085-3089 | RB | denotes | thus |
T18609 | 3090-3092 | VB | denotes | be |
T18610 | 3093-3103 | JJ | denotes | beneficial |
T18611 | 3104-3107 | IN | denotes | for |
T18612 | 3108-3110 | FW | denotes | E. |
T18613 | 3111-3115 | FW | denotes | coli |
T18614 | 3116-3120 | NN | denotes | O157 |
T18615 | 3120-3121 | -COLON- | denotes | : |
T18616 | 3121-3123 | NN | denotes | H7 |
T18617 | 3124-3126 | TO | denotes | to |
T18618 | 3127-3136 | VB | denotes | replicate |
T18619 | 3137-3140 | CC | denotes | and |
T18620 | 3141-3152 | VB | denotes | disseminate |
T18621 | 3153-3155 | IN | denotes | in |
T18622 | 3156-3159 | DT | denotes | the |
T18623 | 3160-3164 | NN | denotes | host |
T18624 | 3166-3168 | IN | denotes | By |
T18625 | 3169-3180 | RB | denotes | selectively |
T18626 | 3181-3191 | VB | denotes | inhibiting |
T18627 | 3192-3196 | NN | denotes | RPS3 |
T18628 | 3197-3200 | CC | denotes | and |
T18629 | 3201-3204 | PRP-DOLLAR- | denotes | its |
T18630 | 3205-3214 | JJ | denotes | attendant |
T18631 | 3215-3220 | NN | denotes | NF-κB |
T18632 | 3221-3229 | NN | denotes | function |
T18633 | 3230-3234 | IN | denotes | with |
T18634 | 3235-3240 | NN | denotes | NleH1 |
T18635 | 3240-3241 | -COMMA- | denotes | , |
T18636 | 3242-3245 | DT | denotes | the |
T18637 | 3246-3254 | NN | denotes | pathogen |
T18638 | 3255-3263 | VB | denotes | achieves |
T18639 | 3264-3267 | DT | denotes | the |
T18640 | 3268-3275 | NN | denotes | ability |
T18641 | 3276-3278 | TO | denotes | to |
T18642 | 3279-3287 | VB | denotes | increase |
T18643 | 3288-3300 | NN | denotes | colonization |
T18644 | 3301-3304 | CC | denotes | and |
T18645 | 3305-3313 | NN | denotes | diarrhea |
T18646 | 3314-3317 | RB | denotes | yet |
T18647 | 3318-3326 | VB | denotes | limiting |
T18648 | 3327-3330 | DT | denotes | the |
T18649 | 3331-3340 | NN | denotes | mortality |
T18650 | 3341-3343 | IN | denotes | of |
T18651 | 3344-3347 | DT | denotes | the |
T18652 | 3348-3352 | NN | denotes | host |
T18653 | 3354-3358 | DT | denotes | This |
T18654 | 3359-3368 | RB | denotes | seemingly |
T18655 | 3369-3380 | JJ | denotes | paradoxical |
T18656 | 3381-3392 | NN | denotes | combination |
T18657 | 3393-3395 | IN | denotes | of |
T18658 | 3396-3403 | NN | denotes | effects |
T18659 | 3404-3408 | VB | denotes | make |
T18660 | 3409-3414 | NN | denotes | sense |
T18661 | 3415-3419 | WRB | denotes | when |
T18662 | 3420-3423 | CD | denotes | one |
T18663 | 3424-3433 | VB | denotes | considers |
T18664 | 3434-3438 | IN | denotes | that |
T18665 | 3439-3448 | VB | denotes | increased |
T18666 | 3449-3458 | JJ | denotes | bacterial |
T18667 | 3459-3463 | NN | denotes | load |
T18668 | 3464-3467 | CC | denotes | and |
T18669 | 3468-3476 | NN | denotes | diarrhea |
T18670 | 3477-3485 | RB | denotes | together |
T18671 | 3486-3490 | IN | denotes | with |
T18672 | 3491-3499 | NN | denotes | survival |
T18673 | 3500-3502 | IN | denotes | of |
T18674 | 3503-3506 | DT | denotes | the |
T18675 | 3507-3515 | JJ | denotes | infected |
T18676 | 3516-3520 | NN | denotes | host |
T18677 | 3521-3526 | MD | denotes | would |
T18678 | 3527-3534 | VB | denotes | promote |
T18679 | 3535-3538 | DT | denotes | the |
T18680 | 3539-3548 | NN | denotes | spreading |
T18681 | 3549-3551 | IN | denotes | of |
T18682 | 3552-3555 | DT | denotes | the |
T18683 | 3556-3564 | NN | denotes | bacteria |
T18684 | 3565-3570 | IN | denotes | among |
T18685 | 3571-3572 | DT | denotes | a |
T18686 | 3573-3583 | NN | denotes | population |
T18687 | 3584-3586 | IN | denotes | of |
T18688 | 3587-3598 | JJ | denotes | susceptible |
T18689 | 3599-3610 | NN | denotes | individuals |
T18690 | 3612-3616 | JJ | denotes | Such |
T18691 | 3617-3624 | NN | denotes | complex |
T18692 | 3625-3628 | CC | denotes | and |
T18693 | 3629-3640 | JJ | denotes | paradoxical |
T18694 | 3641-3653 | JJ | denotes | pathological |
T18695 | 3654-3661 | NN | denotes | effects |
T18696 | 3662-3666 | WDT | denotes | that |
T18697 | 3667-3676 | VB | denotes | influence |
T18698 | 3677-3680 | DT | denotes | the |
T18699 | 3681-3687 | NN | denotes | spread |
T18700 | 3688-3690 | IN | denotes | of |
T18701 | 3691-3698 | NN | denotes | disease |
T18702 | 3699-3702 | VB | denotes | are |
T18703 | 3703-3708 | RB | denotes | often |
T18704 | 3709-3715 | RB | denotes | poorly |
T18705 | 3716-3726 | VB | denotes | understood |
T18706 | 3727-3729 | IN | denotes | at |
T18707 | 3730-3733 | DT | denotes | the |
T18708 | 3734-3743 | JJ | denotes | molecular |
T18709 | 3744-3749 | NN | denotes | level |
T18710 | 3751-3754 | PRP-DOLLAR- | denotes | Our |
T18711 | 3755-3759 | NN | denotes | data |
T18712 | 3760-3769 | VB | denotes | elucidate |
T18713 | 3770-3773 | WRB | denotes | how |
T18714 | 3774-3785 | NN | denotes | alterations |
T18715 | 3786-3788 | IN | denotes | in |
T18716 | 3789-3798 | JJ | denotes | selective |
T18717 | 3799-3804 | NN | denotes | NF-κB |
T18718 | 3805-3813 | NN | denotes | function |
T18719 | 3813-3814 | -COMMA- | denotes | , |
T18720 | 3815-3823 | VB | denotes | achieved |
T18721 | 3824-3826 | IN | denotes | by |
T18722 | 3827-3835 | VB | denotes | impeding |
T18723 | 3836-3840 | NN | denotes | RPS3 |
T18724 | 3840-3841 | -COMMA- | denotes | , |
T18725 | 3842-3845 | CC | denotes | but |
T18726 | 3846-3849 | RB | denotes | not |
T18727 | 3850-3858 | VB | denotes | altering |
T18728 | 3859-3862 | NN | denotes | p65 |
T18729 | 3863-3870 | JJ | denotes | nuclear |
T18730 | 3871-3884 | NN | denotes | translocation |
T18731 | 3884-3885 | -COMMA- | denotes | , |
T18732 | 3886-3889 | MD | denotes | can |
T18733 | 3890-3899 | VB | denotes | influence |
T18734 | 3900-3908 | JJ | denotes | specific |
T18735 | 3909-3918 | NN | denotes | cytokines |
T18736 | 3919-3923 | WDT | denotes | that |
T18737 | 3924-3930 | VB | denotes | affect |
T18738 | 3931-3940 | JJ | denotes | bacterial |
T18739 | 3941-3953 | NN | denotes | colonization |
T18740 | 3953-3954 | -COMMA- | denotes | , |
T18741 | 3955-3963 | NN | denotes | diarrhea |
T18742 | 3964-3972 | NN | denotes | diseases |
T18743 | 3973-3976 | CC | denotes | and |
T18744 | 3977-3986 | NN | denotes | mortality |
T18745 | 3988-3990 | PRP | denotes | It |
T18746 | 3991-3994 | MD | denotes | may |
T18747 | 3995-3997 | VB | denotes | be |
T18748 | 3998-4006 | JJ | denotes | fruitful |
T18749 | 4007-4009 | IN | denotes | in |
T18750 | 4010-4020 | VB | denotes | attempting |
T18751 | 4021-4023 | TO | denotes | to |
T18752 | 4024-4034 | VB | denotes | understand |
T18753 | 4035-4040 | JJ | denotes | other |
T18754 | 4041-4051 | JJ | denotes | infectious |
T18755 | 4052-4055 | CC | denotes | and |
T18756 | 4056-4066 | JJ | denotes | autoimmune |
T18757 | 4067-4075 | NN | denotes | diseases |
T18758 | 4076-4085 | VB | denotes | involving |
T18759 | 4086-4091 | NN | denotes | NF-κB |
T18760 | 4092-4094 | TO | denotes | to |
T18761 | 4095-4103 | VB | denotes | consider |
T18762 | 4104-4113 | JJ | denotes | selective |
T18763 | 4114-4121 | NN | denotes | effects |
T18764 | 4122-4124 | IN | denotes | of |
T18765 | 4125-4133 | NN | denotes | subunits |
T18766 | 4134-4138 | JJ | denotes | such |
T18767 | 4139-4141 | IN | denotes | as |
T18768 | 4142-4146 | NN | denotes | RPS3 |
T18769 | 4147-4149 | IN | denotes | in |
T18770 | 4150-4158 | NN | denotes | addition |
T18771 | 4159-4161 | TO | denotes | to |
T18772 | 4162-4168 | JJ | denotes | global |
T18773 | 4169-4174 | NN | denotes | NF-κB |
T18774 | 4175-4185 | NN | denotes | inhibition |
T18147 | 16-19 | VB | denotes | was |
T18438 | 1950-1960 | JJ | denotes | protective |
R14406 | T18146 | T18147 | arg1Of | RPS3,was |
R14407 | T18146 | T18149 | arg2Of | RPS3,demonstrated |
R14408 | T18146 | T18151 | arg1Of | RPS3,function |
R14409 | T18149 | T18147 | arg2Of | demonstrated,was |
R14410 | T18149 | T18148 | arg1Of | demonstrated,previously |
R14411 | T18151 | T18149 | arg3Of | function,demonstrated |
R14412 | T18151 | T18150 | arg1Of | function,to |
R14413 | T18151 | T18152 | arg1Of | function,as |
R14414 | T18155 | T18152 | arg2Of | subunit,as |
R14415 | T18155 | T18153 | arg1Of | subunit,an |
R14416 | T18155 | T18154 | arg1Of | subunit,integral |
R14417 | T18155 | T18156 | arg1Of | subunit,conferring |
R14418 | T18159 | T18156 | arg2Of | specificity6,conferring |
R14419 | T18159 | T18157 | arg1Of | specificity6,NF-κB |
R14420 | T18159 | T18158 | arg1Of | specificity6,regulatory |
R14421 | T18161 | T18162 | arg1Of | we,sought |
R14422 | T18161 | T18164 | arg1Of | we,elucidate |
R14423 | T18162 | T18160 | arg1Of | sought,Here |
R14424 | T18164 | T18162 | arg2Of | elucidate,sought |
R14425 | T18164 | T18163 | arg1Of | elucidate,to |
R14426 | T18165 | T18164 | arg2Of | how,elucidate |
R14427 | T18168 | T18166 | arg1Of | signaling,NF-κB |
R14428 | T18168 | T18167 | arg1Of | signaling,activation |
R14429 | T18168 | T18169 | arg1Of | signaling,triggers |
R14430 | T18169 | T18165 | arg1Of | triggers,how |
R14431 | T18169 | T18171 | modOf | triggers,to |
R14432 | T18170 | T18169 | arg2Of | RPS3,triggers |
R14433 | T18172 | T18173 | arg1Of | translocate,and |
R14434 | T18173 | T18171 | arg1Of | and,to |
R14435 | T18174 | T18173 | arg2Of | participate,and |
R14436 | T18174 | T18175 | arg1Of | participate,in |
R14437 | T18177 | T18172 | arg2Of | function,translocate |
R14438 | T18177 | T18174 | arg2Of | function,participate |
R14439 | T18177 | T18176 | arg1Of | function,NF-κB |
R14440 | T18177 | T18178 | arg1Of | function,in |
R14441 | T18180 | T18178 | arg2Of | nucleus,in |
R14442 | T18180 | T18179 | arg1Of | nucleus,the |
R14443 | T18181 | T18182 | arg1Of | We,demonstrate |
R14444 | T18187 | T18184 | arg1Of | phosphorylation,IKKβ-mediated |
R14445 | T18187 | T18185 | arg1Of | phosphorylation,RPS3 |
R14446 | T18187 | T18186 | arg1Of | phosphorylation,S209 |
R14447 | T18187 | T18188 | arg1Of | phosphorylation,represents |
R14448 | T18188 | T18182 | arg2Of | represents,demonstrate |
R14449 | T18188 | T18183 | arg1Of | represents,that |
R14450 | T18191 | T18188 | arg2Of | determinant,represents |
R14451 | T18191 | T18189 | arg1Of | determinant,a |
R14452 | T18191 | T18190 | arg1Of | determinant,critical |
R14453 | T18191 | T18192 | arg1Of | determinant,in |
R14454 | T18193 | T18192 | arg2Of | governing,in |
R14455 | T18196 | T18193 | arg2Of | import,governing |
R14456 | T18196 | T18194 | arg1Of | import,its |
R14457 | T18196 | T18195 | arg1Of | import,nuclear |
R14458 | T18196 | T18198 | arg1Of | import,unveiling |
R14459 | T18198 | T18197 | arg1Of | unveiling,thus |
R14460 | T18201 | T18198 | arg2Of | mechanism,unveiling |
R14461 | T18201 | T18199 | arg1Of | mechanism,a |
R14462 | T18201 | T18200 | arg1Of | mechanism,novel |
R14463 | T18201 | T18202 | arg1Of | mechanism,behind |
R14464 | T18205 | T18202 | arg2Of | specificity,behind |
R14465 | T18205 | T18203 | arg1Of | specificity,NF-κB |
R14466 | T18205 | T18204 | arg1Of | specificity,regulatory |
R14467 | T18206 | T18207 | arg1Of | IKKβ,is |
R14468 | T18210 | T18207 | arg2Of | kinase,is |
R14469 | T18210 | T18208 | arg1Of | kinase,the |
R14470 | T18210 | T18209 | arg1Of | kinase,major |
R14471 | T18210 | T18211 | arg1Of | kinase,that |
R14472 | T18210 | T18212 | arg1Of | kinase,phosphorylates |
R14473 | T18212 | T18214 | arg1Of | phosphorylates,in |
R14474 | T18212 | T18219 | arg1Of | phosphorylates,"," |
R14475 | T18212 | T18220 | modOf | phosphorylates,leading |
R14476 | T18213 | T18212 | arg2Of | IκBs,phosphorylates |
R14477 | T18218 | T18214 | arg2Of | pathway,in |
R14478 | T18218 | T18215 | arg1Of | pathway,the |
R14479 | T18218 | T18216 | arg1Of | pathway,classical |
R14480 | T18218 | T18217 | arg1Of | pathway,NF-κB |
R14481 | T18220 | T18221 | arg1Of | leading,to |
R14482 | T18224 | T18221 | arg2Of | degradation40,to |
R14483 | T18224 | T18222 | arg1Of | degradation40,their |
R14484 | T18224 | T18223 | arg1Of | degradation40,subsequent |
R14485 | T18227 | T18228 | arg1Of | RPS3,possesses |
R14486 | T18228 | T18225 | arg1Of | possesses,Strikingly |
R14487 | T18228 | T18226 | arg1Of | possesses,"," |
R14488 | T18228 | T18234 | arg1Of | possesses,; |
R14489 | T18233 | T18228 | arg2Of | motif,possesses |
R14490 | T18233 | T18229 | arg1Of | motif,not |
R14491 | T18233 | T18230 | arg1Of | motif,any |
R14492 | T18233 | T18231 | arg1Of | motif,consensus |
R14493 | T18233 | T18232 | arg1Of | motif,IKK |
R14494 | T18237 | T18238 | arg1Of | S209,is |
R14495 | T18237 | T18239 | arg2Of | S209,centered |
R14496 | T18239 | T18234 | arg2Of | centered,; |
R14497 | T18239 | T18235 | arg1Of | centered,instead |
R14498 | T18239 | T18236 | arg1Of | centered,"," |
R14499 | T18239 | T18238 | arg2Of | centered,is |
R14500 | T18239 | T18240 | arg1Of | centered,in |
R14501 | T18244 | T18240 | arg2Of | motif,in |
R14502 | T18244 | T18241 | arg1Of | motif,a |
R14503 | T18244 | T18242 | arg1Of | motif,consensus |
R14504 | T18244 | T18243 | arg1Of | motif,CK2 |
R14505 | T18247 | T18245 | arg1Of | observation,The |
R14506 | T18247 | T18246 | arg1Of | observation,recent |
R14507 | T18250 | T18249 | arg1Of | IKKβ,human |
R14508 | T18250 | T18251 | arg1Of | IKKβ,displayed |
R14509 | T18251 | T18247 | arg2Of | displayed,observation |
R14510 | T18251 | T18248 | arg1Of | displayed,that |
R14511 | T18251 | T18256 | arg1Of | displayed,with |
R14512 | T18255 | T18251 | arg2Of | coincides,displayed |
R14513 | T18255 | T18252 | arg1Of | coincides,CK2-like |
R14514 | T18255 | T18253 | arg1Of | coincides,phosphorylation |
R14515 | T18255 | T18254 | arg1Of | coincides,specificity29 |
R14516 | T18261 | T18257 | arg1Of | IKKβ,our |
R14517 | T18261 | T18258 | arg1Of | IKKβ,evidence |
R14518 | T18261 | T18259 | arg1Of | IKKβ,that |
R14519 | T18261 | T18260 | arg1Of | IKKβ,recombinant |
R14520 | T18261 | T18263 | arg1Of | IKKβ,but |
R14521 | T18263 | T18256 | arg2Of | but,with |
R14522 | T18263 | T18262 | arg1Of | but,"," |
R14523 | T18263 | T18264 | arg1Of | but,not |
R14524 | T18263 | T18266 | arg1Of | but,"," |
R14525 | T18265 | T18263 | arg2Of | IKKα,but |
R14526 | T18268 | T18266 | arg2Of | RPS3,"," |
R14527 | T18268 | T18267 | arg2Of | RPS3,phosphorylated |
R14528 | T18269 | T18270 | arg1Of | We,found |
R14529 | T18272 | T18271 | arg1Of | phosphorylation,this |
R14530 | T18272 | T18273 | arg1Of | phosphorylation,is |
R14531 | T18273 | T18270 | arg2Of | is,found |
R14532 | T18276 | T18273 | arg2Of | modulation,is |
R14533 | T18276 | T18274 | arg1Of | modulation,a |
R14534 | T18276 | T18275 | arg1Of | modulation,critical |
R14535 | T18276 | T18277 | arg1Of | modulation,for |
R14536 | T18280 | T18278 | arg1Of | translocation,RPS3 |
R14537 | T18280 | T18279 | arg1Of | translocation,nuclear |
R14538 | T18280 | T18281 | arg1Of | translocation,( |
R14539 | T18280 | T18285 | arg1Of | translocation,and |
R14540 | T18282 | T18281 | arg2Of | via,( |
R14541 | T18283 | T18282 | arg2Of | importin-α,via |
R14542 | T18284 | T18281 | arg3Of | ),( |
R14543 | T18285 | T18277 | arg2Of | and,for |
R14544 | T18286 | T18285 | arg2Of | engagement,and |
R14545 | T18286 | T18287 | arg1Of | engagement,in |
R14546 | T18290 | T18287 | arg2Of | transcription,in |
R14547 | T18290 | T18288 | arg1Of | transcription,specific |
R14548 | T18290 | T18289 | arg1Of | transcription,NF-κB |
R14549 | T18291 | T18292 | arg1Of | CK2,was |
R14550 | T18291 | T18294 | arg2Of | CK2,shown |
R14551 | T18291 | T18296 | arg1Of | CK2,phosphorylate |
R14552 | T18291 | T18300 | arg1Of | CK2,bind |
R14553 | T18291 | T18303 | arg1Of | CK2,phosphorylate |
R14554 | T18294 | T18292 | arg2Of | shown,was |
R14555 | T18294 | T18293 | arg1Of | shown,previously |
R14556 | T18294 | T18305 | arg1Of | shown,"," |
R14557 | T18294 | T18306 | arg1Of | shown,however |
R14558 | T18294 | T18307 | arg1Of | shown,"," |
R14559 | T18296 | T18295 | arg1Of | phosphorylate,to |
R14560 | T18296 | T18298 | arg1Of | phosphorylate,and |
R14561 | T18297 | T18296 | arg2Of | p65,phosphorylate |
R14562 | T18298 | T18294 | arg3Of | and,shown |
R14563 | T18300 | T18301 | arg1Of | bind,to |
R14564 | T18300 | T18302 | arg1Of | bind,and |
R14565 | T18302 | T18298 | arg2Of | and,and |
R14566 | T18302 | T18299 | arg1Of | and,to |
R14567 | T18303 | T18302 | arg2Of | phosphorylate,and |
R14568 | T18304 | T18303 | arg2Of | IKKβ41-43,phosphorylate |
R14569 | T18307 | T18329 | arg1Of | ",",in |
R14570 | T18308 | T18309 | arg1Of | we,ruled |
R14571 | T18309 | T18307 | arg2Of | ruled,"," |
R14572 | T18309 | T18310 | arg1Of | ruled,out |
R14573 | T18309 | T18324 | arg1Of | ruled,because |
R14574 | T18312 | T18309 | arg2Of | possibility,ruled |
R14575 | T18312 | T18311 | arg1Of | possibility,the |
R14576 | T18316 | T18314 | arg1Of | CK2,the |
R14577 | T18316 | T18315 | arg1Of | CK2,IKKβ-bound |
R14578 | T18316 | T18317 | arg1Of | CK2,could |
R14579 | T18316 | T18318 | arg1Of | CK2,account |
R14580 | T18318 | T18312 | arg2Of | account,possibility |
R14581 | T18318 | T18313 | arg1Of | account,that |
R14582 | T18318 | T18317 | arg2Of | account,could |
R14583 | T18318 | T18319 | arg1Of | account,for |
R14584 | T18323 | T18319 | arg2Of | phosphorylation,for |
R14585 | T18323 | T18320 | arg1Of | phosphorylation,the |
R14586 | T18323 | T18321 | arg2Of | phosphorylation,observed |
R14587 | T18323 | T18322 | arg1Of | phosphorylation,RPS3 |
R14588 | T18326 | T18325 | arg1Of | CK2,no |
R14589 | T18326 | T18327 | arg1Of | CK2,was |
R14590 | T18326 | T18328 | arg2Of | CK2,detected |
R14591 | T18328 | T18324 | arg2Of | detected,because |
R14592 | T18328 | T18327 | arg2Of | detected,was |
R14593 | T18332 | T18329 | arg2Of | preparations,in |
R14594 | T18332 | T18330 | arg1Of | preparations,the |
R14595 | T18332 | T18331 | arg1Of | preparations,IKKβ |
R14596 | T18332 | T18333 | arg2Of | preparations,used |
R14597 | T18333 | T18334 | arg1Of | used,for |
R14598 | T18337 | T18336 | arg1Of | vitro,in |
R14599 | T18339 | T18334 | arg2Of | assay,for |
R14600 | T18339 | T18335 | arg1Of | assay,the |
R14601 | T18339 | T18337 | arg1Of | assay,vitro |
R14602 | T18339 | T18338 | arg1Of | assay,kinase |
R14603 | T18341 | T18343 | arg1Of | RPS3,harbors |
R14604 | T18343 | T18340 | arg2Of | harbors,Because |
R14605 | T18343 | T18342 | arg1Of | harbors,only |
R14606 | T18346 | T18344 | arg1Of | motif,the |
R14607 | T18346 | T18345 | arg1Of | motif,CK2 |
R14608 | T18346 | T18347 | arg1Of | motif,and |
R14609 | T18347 | T18343 | arg2Of | and,harbors |
R14610 | T18352 | T18347 | arg2Of | motif,and |
R14611 | T18352 | T18348 | arg1Of | motif,not |
R14612 | T18352 | T18349 | arg1Of | motif,a |
R14613 | T18352 | T18350 | arg1Of | motif,traditional |
R14614 | T18352 | T18351 | arg1Of | motif,IKK |
R14615 | T18357 | T18354 | arg1Of | function,this |
R14616 | T18357 | T18355 | arg1Of | function,RPS3 |
R14617 | T18357 | T18356 | arg1Of | function,regulatory |
R14618 | T18357 | T18358 | arg1Of | function,could |
R14619 | T18357 | T18359 | arg1Of | function,explain |
R14620 | T18359 | T18340 | arg1Of | explain,Because |
R14621 | T18359 | T18353 | arg1Of | explain,"," |
R14622 | T18359 | T18358 | arg2Of | explain,could |
R14623 | T18360 | T18359 | arg2Of | why,explain |
R14624 | T18361 | T18362 | arg1Of | IKK,harbors |
R14625 | T18362 | T18360 | arg1Of | harbors,why |
R14626 | T18367 | T18362 | arg2Of | capability,harbors |
R14627 | T18367 | T18363 | arg1Of | capability,the |
R14628 | T18367 | T18364 | arg1Of | capability,alternative |
R14629 | T18367 | T18365 | arg1Of | capability,substrate |
R14630 | T18367 | T18366 | arg1Of | capability,phosphorylation |
R14631 | T18369 | T18368 | arg1Of | importantly,More |
R14632 | T18372 | T18371 | arg1Of | study,our |
R14633 | T18372 | T18373 | arg1Of | study,has |
R14634 | T18372 | T18374 | arg1Of | study,elucidated |
R14635 | T18374 | T18369 | arg1Of | elucidated,importantly |
R14636 | T18374 | T18370 | arg1Of | elucidated,"," |
R14637 | T18374 | T18373 | arg2Of | elucidated,has |
R14638 | T18375 | T18374 | arg2Of | how,elucidated |
R14639 | T18376 | T18377 | arg1Of | RPS3,is |
R14640 | T18376 | T18379 | arg2Of | RPS3,integrated |
R14641 | T18379 | T18375 | arg1Of | integrated,how |
R14642 | T18379 | T18377 | arg2Of | integrated,is |
R14643 | T18379 | T18378 | arg1Of | integrated,biochemically |
R14644 | T18379 | T18380 | arg1Of | integrated,into |
R14645 | T18379 | T18384 | arg1Of | integrated,in |
R14646 | T18383 | T18380 | arg2Of | signaling,into |
R14647 | T18383 | T18381 | arg1Of | signaling,NF-κB |
R14648 | T18383 | T18382 | arg1Of | signaling,activation |
R14649 | T18386 | T18384 | arg2Of | manner,in |
R14650 | T18386 | T18385 | arg1Of | manner,a |
R14651 | T18386 | T18387 | arg1Of | manner,that |
R14652 | T18386 | T18388 | arg1Of | manner,is |
R14653 | T18386 | T18389 | arg1Of | manner,pivotal |
R14654 | T18389 | T18388 | arg2Of | pivotal,is |
R14655 | T18389 | T18390 | arg1Of | pivotal,for |
R14656 | T18392 | T18390 | arg2Of | pathogenesis,for |
R14657 | T18392 | T18391 | arg1Of | pathogenesis,the |
R14658 | T18392 | T18393 | arg1Of | pathogenesis,of |
R14659 | T18392 | T18399 | arg1Of | pathogenesis,: |
R14660 | T18398 | T18393 | arg2Of | O157,of |
R14661 | T18398 | T18394 | arg1Of | O157,foodborne |
R14662 | T18398 | T18395 | arg1Of | O157,pathogen |
R14663 | T18398 | T18396 | arg1Of | O157,E. |
R14664 | T18398 | T18397 | arg1Of | O157,coli |
R14665 | T18400 | T18399 | arg2Of | H7,: |
R14666 | T18404 | T18401 | arg1Of | phosphorylation,IKKβ-mediated |
R14667 | T18404 | T18402 | arg1Of | phosphorylation,RPS3 |
R14668 | T18404 | T18403 | arg1Of | phosphorylation,S209 |
R14669 | T18404 | T18405 | arg1Of | phosphorylation,is |
R14670 | T18408 | T18405 | arg2Of | target,is |
R14671 | T18408 | T18406 | arg1Of | target,a |
R14672 | T18408 | T18407 | arg1Of | target,critical |
R14673 | T18408 | T18409 | arg2Of | target,modulated |
R14674 | T18412 | T18409 | arg1Of | pathogen,modulated |
R14675 | T18412 | T18410 | arg2Of | pathogen,by |
R14676 | T18412 | T18411 | arg1Of | pathogen,this |
R14677 | T18412 | T18413 | modOf | pathogen,to |
R14678 | T18414 | T18413 | arg1Of | subvert,to |
R14679 | T18417 | T18414 | arg2Of | signaling,subvert |
R14680 | T18417 | T18415 | arg1Of | signaling,host |
R14681 | T18417 | T18416 | arg1Of | signaling,NF-κB |
R14682 | T18421 | T18418 | arg1Of | NleH1,The |
R14683 | T18421 | T18419 | arg1Of | NleH1,bacterial |
R14684 | T18421 | T18420 | arg1Of | NleH1,effector |
R14685 | T18421 | T18423 | arg1Of | NleH1,binds |
R14686 | T18421 | T18433 | arg1Of | NleH1,suppresses |
R14687 | T18423 | T18424 | arg1Of | binds,to |
R14688 | T18423 | T18431 | arg1Of | binds,and |
R14689 | T18425 | T18424 | arg2Of | RPS3,to |
R14690 | T18425 | T18427 | arg2Of | RPS3,injected |
R14691 | T18427 | T18426 | arg1Of | injected,once |
R14692 | T18427 | T18428 | arg1Of | injected,into |
R14693 | T18430 | T18428 | arg2Of | cells,into |
R14694 | T18430 | T18429 | arg1Of | cells,host |
R14695 | T18431 | T18422 | arg1Of | and,specifically |
R14696 | T18433 | T18431 | arg2Of | suppresses,and |
R14697 | T18433 | T18432 | arg1Of | suppresses,profoundly |
R14698 | T18434 | T18435 | arg1Of | NF-κB,and |
R14699 | T18435 | T18433 | arg2Of | and,suppresses |
R14700 | T18440 | T18435 | arg2Of | responses9,and |
R14701 | T18440 | T18436 | arg1Of | responses9,its |
R14702 | T18440 | T18437 | arg1Of | responses9,attendant |
R14703 | T18440 | T18438 | arg1Of | responses9,protective |
R14704 | T18440 | T18439 | arg1Of | responses9,immune |
R14705 | T18442 | T18441 | arg1Of | data,Our |
R14706 | T18442 | T18444 | arg1Of | data,show |
R14707 | T18444 | T18443 | arg1Of | show,now |
R14708 | T18446 | T18448 | arg1Of | NleH1,inhibits |
R14709 | T18448 | T18444 | arg2Of | inhibits,show |
R14710 | T18448 | T18445 | arg1Of | inhibits,that |
R14711 | T18448 | T18447 | arg1Of | inhibits,selectively |
R14712 | T18448 | T18451 | arg1Of | inhibits,"," |
R14713 | T18450 | T18448 | arg2Of | phosphorylation,inhibits |
R14714 | T18450 | T18449 | arg1Of | phosphorylation,RPS3 |
R14715 | T18453 | T18448 | arg3Of | retarding,inhibits |
R14716 | T18453 | T18452 | arg1Of | retarding,thus |
R14717 | T18453 | T18461 | arg1Of | retarding,"," |
R14718 | T18453 | T18462 | arg1Of | retarding,without |
R14719 | T18456 | T18455 | arg1Of | translocation,nuclear |
R14720 | T18456 | T18457 | arg1Of | translocation,and |
R14721 | T18457 | T18453 | arg2Of | and,retarding |
R14722 | T18457 | T18454 | arg1Of | and,its |
R14723 | T18460 | T18457 | arg2Of | function,and |
R14724 | T18460 | T18458 | arg1Of | function,subsequent |
R14725 | T18460 | T18459 | arg1Of | function,NF-κB |
R14726 | T18463 | T18462 | arg2Of | altering,without |
R14727 | T18466 | T18463 | arg2Of | signaling,altering |
R14728 | T18466 | T18464 | arg1Of | signaling,other |
R14729 | T18466 | T18465 | arg1Of | signaling,NF-κB |
R14730 | T18468 | T18469 | arg1Of | NleH1,did |
R14731 | T18468 | T18472 | arg1Of | NleH1,phosphorylate |
R14732 | T18472 | T18467 | arg2Of | phosphorylate,Although |
R14733 | T18472 | T18469 | arg2Of | phosphorylate,did |
R14734 | T18472 | T18470 | arg1Of | phosphorylate,not |
R14735 | T18472 | T18471 | arg1Of | phosphorylate,directly |
R14736 | T18473 | T18472 | arg2Of | IKKβ,phosphorylate |
R14737 | T18477 | T18475 | arg1Of | activity,its |
R14738 | T18477 | T18476 | arg1Of | activity,kinase |
R14739 | T18477 | T18478 | arg1Of | activity,was |
R14740 | T18477 | T18479 | arg2Of | activity,required |
R14741 | T18477 | T18481 | arg1Of | activity,inhibit |
R14742 | T18479 | T18467 | arg1Of | required,Although |
R14743 | T18479 | T18474 | arg1Of | required,"," |
R14744 | T18479 | T18478 | arg2Of | required,was |
R14745 | T18481 | T18479 | arg3Of | inhibit,required |
R14746 | T18481 | T18480 | arg1Of | inhibit,to |
R14747 | T18485 | T18481 | arg2Of | phosphorylation,inhibit |
R14748 | T18485 | T18482 | arg1Of | phosphorylation,IKKβ-mediated |
R14749 | T18485 | T18483 | arg1Of | phosphorylation,RPS3 |
R14750 | T18485 | T18484 | arg1Of | phosphorylation,S209 |
R14751 | T18488 | T18486 | arg1Of | pathogens,Many |
R14752 | T18488 | T18487 | arg1Of | pathogens,bacteria |
R14753 | T18488 | T18489 | arg1Of | pathogens,have |
R14754 | T18489 | T18501 | arg1Of | have,"," |
R14755 | T18489 | T18502 | arg1Of | have,whereas |
R14756 | T18490 | T18489 | arg2Of | products,have |
R14757 | T18490 | T18491 | arg1Of | products,that |
R14758 | T18490 | T18492 | arg1Of | products,target |
R14759 | T18494 | T18492 | arg2Of | kinases,target |
R14760 | T18494 | T18493 | arg1Of | kinases,key |
R14761 | T18494 | T18496 | arg1Of | kinases,inactivate |
R14762 | T18496 | T18492 | arg3Of | inactivate,target |
R14763 | T18496 | T18495 | arg1Of | inactivate,to |
R14764 | T18496 | T18498 | arg1Of | inactivate,in |
R14765 | T18497 | T18496 | arg2Of | them,inactivate |
R14766 | T18500 | T18498 | arg2Of | cells,in |
R14767 | T18500 | T18499 | arg1Of | cells,host |
R14768 | T18505 | T18503 | arg1Of | O157,E. |
R14769 | T18505 | T18504 | arg1Of | O157,coli |
R14770 | T18507 | T18508 | arg1Of | H7,employed |
R14771 | T18507 | T18511 | arg1Of | H7,steer |
R14772 | T18508 | T18502 | arg2Of | employed,whereas |
R14773 | T18508 | T18505 | arg1Of | employed,O157 |
R14774 | T18508 | T18506 | arg1Of | employed,: |
R14775 | T18509 | T18508 | arg2Of | NleH1,employed |
R14776 | T18511 | T18508 | arg3Of | steer,employed |
R14777 | T18511 | T18510 | arg1Of | steer,to |
R14778 | T18514 | T18511 | arg2Of | specificity,steer |
R14779 | T18514 | T18512 | arg1Of | specificity,the |
R14780 | T18514 | T18513 | arg1Of | specificity,substrate |
R14781 | T18514 | T18515 | arg1Of | specificity,of |
R14782 | T18518 | T18517 | arg1Of | specifically,thus |
R14783 | T18519 | T18516 | arg1Of | fine-tuning,IKKβ |
R14784 | T18519 | T18518 | arg1Of | fine-tuning,specifically |
R14785 | T18522 | T18515 | arg2Of | signaling,of |
R14786 | T18522 | T18519 | arg1Of | signaling,fine-tuning |
R14787 | T18522 | T18520 | arg1Of | signaling,host |
R14788 | T18522 | T18521 | arg1Of | signaling,NF-κB |
R14789 | T18523 | T18524 | arg1Of | This,could |
R14790 | T18523 | T18525 | arg1Of | This,represent |
R14791 | T18525 | T18524 | arg2Of | represent,could |
R14792 | T18528 | T18525 | arg2Of | strategy,represent |
R14793 | T18528 | T18526 | arg1Of | strategy,a |
R14794 | T18528 | T18527 | arg1Of | strategy,novel |
R14795 | T18528 | T18529 | modOf | strategy,to |
R14796 | T18530 | T18529 | arg1Of | fine-tune,to |
R14797 | T18533 | T18530 | arg2Of | signaling,fine-tune |
R14798 | T18533 | T18531 | arg1Of | signaling,host |
R14799 | T18533 | T18532 | arg1Of | signaling,NF-κB |
R14800 | T18533 | T18534 | arg1Of | signaling,that |
R14801 | T18533 | T18535 | arg1Of | signaling,could |
R14802 | T18533 | T18536 | arg1Of | signaling,be |
R14803 | T18533 | T18537 | arg2Of | signaling,shared |
R14804 | T18537 | T18535 | arg2Of | shared,could |
R14805 | T18537 | T18536 | arg2Of | shared,be |
R14806 | T18540 | T18537 | arg1Of | pathogens,shared |
R14807 | T18540 | T18538 | arg2Of | pathogens,by |
R14808 | T18540 | T18539 | arg1Of | pathogens,other |
R14809 | T18542 | T18541 | arg1Of | data,These |
R14810 | T18542 | T18543 | arg1Of | data,provide |
R14811 | T18545 | T18543 | arg2Of | insights,provide |
R14812 | T18545 | T18544 | arg1Of | insights,new |
R14813 | T18545 | T18546 | arg1Of | insights,into |
R14814 | T18549 | T18548 | arg1Of | understood,poorly |
R14815 | T18551 | T18546 | arg2Of | mechanism,into |
R14816 | T18551 | T18547 | arg1Of | mechanism,the |
R14817 | T18551 | T18549 | arg1Of | mechanism,understood |
R14818 | T18551 | T18550 | arg1Of | mechanism,action |
R14819 | T18551 | T18552 | arg1Of | mechanism,for |
R14820 | T18555 | T18552 | arg2Of | effectors,for |
R14821 | T18555 | T18553 | arg1Of | effectors,most |
R14822 | T18555 | T18554 | arg1Of | effectors,T3SS |
R14823 | T18556 | T18557 | arg1Of | NleH1,attenuates |
R14824 | T18557 | T18570 | arg1Of | attenuates,"," |
R14825 | T18559 | T18557 | arg2Of | transcription,attenuates |
R14826 | T18559 | T18558 | arg1Of | transcription,the |
R14827 | T18559 | T18560 | arg1Of | transcription,of |
R14828 | T18561 | T18563 | arg1Of | RPS3-dependent,but |
R14829 | T18563 | T18560 | arg2Of | but,of |
R14830 | T18563 | T18562 | arg1Of | but,"," |
R14831 | T18563 | T18564 | arg1Of | but,not |
R14832 | T18569 | T18563 | arg2Of | genes,but |
R14833 | T18569 | T18565 | arg1Of | genes,all |
R14834 | T18569 | T18566 | arg1Of | genes,"," |
R14835 | T18569 | T18567 | arg1Of | genes,NF-κB |
R14836 | T18569 | T18568 | arg1Of | genes,target |
R14837 | T18572 | T18571 | arg2Of | particular,in |
R14838 | T18574 | T18557 | arg3Of | genes,attenuates |
R14839 | T18574 | T18571 | arg1Of | genes,in |
R14840 | T18574 | T18573 | arg1Of | genes,those |
R14841 | T18574 | T18575 | arg2Of | genes,associated |
R14842 | T18575 | T18576 | arg1Of | associated,with |
R14843 | T18579 | T18576 | arg2Of | responses,with |
R14844 | T18579 | T18577 | arg1Of | responses,acute |
R14845 | T18579 | T18578 | arg1Of | responses,proinflammatory |
R14846 | T18579 | T18580 | arg1Of | responses,"," |
R14847 | T18579 | T18581 | arg1Of | responses,including |
R14848 | T18582 | T18583 | arg1Of | IL8,and |
R14849 | T18583 | T18581 | arg2Of | and,including |
R14850 | T18584 | T18583 | arg2Of | TNF,and |
R14851 | T18586 | T18585 | arg2Of | contrast,In |
R14852 | T18588 | T18589 | arg1Of | NleH1,does |
R14853 | T18588 | T18591 | arg1Of | NleH1,block |
R14854 | T18591 | T18585 | arg1Of | block,In |
R14855 | T18591 | T18587 | arg1Of | block,"," |
R14856 | T18591 | T18589 | arg2Of | block,does |
R14857 | T18591 | T18590 | arg1Of | block,not |
R14858 | T18595 | T18591 | arg2Of | translocation,block |
R14859 | T18595 | T18592 | arg1Of | translocation,NF-κB |
R14860 | T18595 | T18593 | arg1Of | translocation,p65 |
R14861 | T18595 | T18594 | arg1Of | translocation,nuclear |
R14862 | T18595 | T18596 | arg1Of | translocation,"," |
R14863 | T18595 | T18597 | arg1Of | translocation,which |
R14864 | T18595 | T18598 | arg1Of | translocation,suggests |
R14865 | T18601 | T18602 | arg1Of | p65-dependent,but |
R14866 | T18603 | T18602 | arg2Of | RPS3-independent,but |
R14867 | T18606 | T18600 | arg1Of | genes,certain |
R14868 | T18606 | T18601 | arg1Of | genes,p65-dependent |
R14869 | T18606 | T18603 | arg1Of | genes,RPS3-independent |
R14870 | T18606 | T18604 | arg1Of | genes,NF-κB |
R14871 | T18606 | T18605 | arg1Of | genes,target |
R14872 | T18606 | T18607 | arg1Of | genes,might |
R14873 | T18606 | T18609 | arg1Of | genes,be |
R14874 | T18606 | T18610 | arg1Of | genes,beneficial |
R14875 | T18609 | T18598 | arg2Of | be,suggests |
R14876 | T18609 | T18599 | arg1Of | be,that |
R14877 | T18609 | T18607 | arg2Of | be,might |
R14878 | T18609 | T18608 | arg1Of | be,thus |
R14879 | T18610 | T18609 | arg2Of | beneficial,be |
R14880 | T18610 | T18611 | arg1Of | beneficial,for |
R14881 | T18614 | T18611 | arg2Of | O157,for |
R14882 | T18614 | T18612 | arg1Of | O157,E. |
R14883 | T18614 | T18613 | arg1Of | O157,coli |
R14884 | T18614 | T18615 | arg1Of | O157,: |
R14885 | T18614 | T18617 | modOf | O157,to |
R14886 | T18616 | T18618 | arg2Of | H7,replicate |
R14887 | T18616 | T18620 | arg2Of | H7,disseminate |
R14888 | T18618 | T18619 | arg1Of | replicate,and |
R14889 | T18619 | T18617 | arg1Of | and,to |
R14890 | T18619 | T18621 | arg1Of | and,in |
R14891 | T18620 | T18619 | arg2Of | disseminate,and |
R14892 | T18623 | T18621 | arg2Of | host,in |
R14893 | T18623 | T18622 | arg1Of | host,the |
R14894 | T18626 | T18624 | arg2Of | inhibiting,By |
R14895 | T18626 | T18625 | arg1Of | inhibiting,selectively |
R14896 | T18627 | T18628 | arg1Of | RPS3,and |
R14897 | T18628 | T18626 | arg2Of | and,inhibiting |
R14898 | T18632 | T18628 | arg2Of | function,and |
R14899 | T18632 | T18629 | arg1Of | function,its |
R14900 | T18632 | T18630 | arg1Of | function,attendant |
R14901 | T18632 | T18631 | arg1Of | function,NF-κB |
R14902 | T18632 | T18633 | arg1Of | function,with |
R14903 | T18634 | T18633 | arg2Of | NleH1,with |
R14904 | T18637 | T18626 | arg1Of | pathogen,inhibiting |
R14905 | T18637 | T18636 | arg1Of | pathogen,the |
R14906 | T18637 | T18638 | arg1Of | pathogen,achieves |
R14907 | T18638 | T18624 | arg1Of | achieves,By |
R14908 | T18638 | T18635 | arg1Of | achieves,"," |
R14909 | T18640 | T18638 | arg2Of | ability,achieves |
R14910 | T18640 | T18639 | arg1Of | ability,the |
R14911 | T18640 | T18641 | modOf | ability,to |
R14912 | T18642 | T18641 | arg1Of | increase,to |
R14913 | T18643 | T18644 | arg1Of | colonization,and |
R14914 | T18644 | T18642 | arg2Of | and,increase |
R14915 | T18644 | T18647 | arg1Of | and,limiting |
R14916 | T18645 | T18644 | arg2Of | diarrhea,and |
R14917 | T18647 | T18646 | arg1Of | limiting,yet |
R14918 | T18649 | T18647 | arg2Of | mortality,limiting |
R14919 | T18649 | T18648 | arg1Of | mortality,the |
R14920 | T18649 | T18650 | arg1Of | mortality,of |
R14921 | T18652 | T18650 | arg2Of | host,of |
R14922 | T18652 | T18651 | arg1Of | host,the |
R14923 | T18655 | T18654 | arg1Of | paradoxical,seemingly |
R14924 | T18656 | T18653 | arg1Of | combination,This |
R14925 | T18656 | T18655 | arg1Of | combination,paradoxical |
R14926 | T18656 | T18657 | arg1Of | combination,of |
R14927 | T18656 | T18659 | arg1Of | combination,make |
R14928 | T18658 | T18657 | arg2Of | effects,of |
R14929 | T18659 | T18661 | arg1Of | make,when |
R14930 | T18660 | T18659 | arg2Of | sense,make |
R14931 | T18662 | T18663 | arg1Of | one,considers |
R14932 | T18663 | T18661 | arg2Of | considers,when |
R14933 | T18667 | T18665 | arg2Of | load,increased |
R14934 | T18667 | T18666 | arg1Of | load,bacterial |
R14935 | T18667 | T18668 | arg1Of | load,and |
R14936 | T18668 | T18671 | arg1Of | and,with |
R14937 | T18668 | T18677 | arg1Of | and,would |
R14938 | T18668 | T18678 | arg1Of | and,promote |
R14939 | T18669 | T18668 | arg2Of | diarrhea,and |
R14940 | T18671 | T18670 | arg1Of | with,together |
R14941 | T18672 | T18671 | arg2Of | survival,with |
R14942 | T18672 | T18673 | arg1Of | survival,of |
R14943 | T18676 | T18673 | arg2Of | host,of |
R14944 | T18676 | T18674 | arg1Of | host,the |
R14945 | T18676 | T18675 | arg1Of | host,infected |
R14946 | T18678 | T18663 | arg2Of | promote,considers |
R14947 | T18678 | T18664 | arg1Of | promote,that |
R14948 | T18678 | T18677 | arg2Of | promote,would |
R14949 | T18678 | T18684 | arg1Of | promote,among |
R14950 | T18680 | T18678 | arg2Of | spreading,promote |
R14951 | T18680 | T18679 | arg1Of | spreading,the |
R14952 | T18680 | T18681 | arg1Of | spreading,of |
R14953 | T18683 | T18681 | arg2Of | bacteria,of |
R14954 | T18683 | T18682 | arg1Of | bacteria,the |
R14955 | T18686 | T18684 | arg2Of | population,among |
R14956 | T18686 | T18685 | arg1Of | population,a |
R14957 | T18686 | T18687 | arg1Of | population,of |
R14958 | T18689 | T18687 | arg2Of | individuals,of |
R14959 | T18689 | T18688 | arg1Of | individuals,susceptible |
R14960 | T18691 | T18690 | arg1Of | complex,Such |
R14961 | T18691 | T18692 | arg1Of | complex,and |
R14962 | T18692 | T18702 | arg1Of | and,are |
R14963 | T18692 | T18705 | arg2Of | and,understood |
R14964 | T18695 | T18692 | arg2Of | effects,and |
R14965 | T18695 | T18693 | arg1Of | effects,paradoxical |
R14966 | T18695 | T18694 | arg1Of | effects,pathological |
R14967 | T18695 | T18696 | arg1Of | effects,that |
R14968 | T18695 | T18697 | arg1Of | effects,influence |
R14969 | T18699 | T18697 | arg2Of | spread,influence |
R14970 | T18699 | T18698 | arg1Of | spread,the |
R14971 | T18699 | T18700 | arg1Of | spread,of |
R14972 | T18701 | T18700 | arg2Of | disease,of |
R14973 | T18705 | T18702 | arg2Of | understood,are |
R14974 | T18705 | T18703 | arg1Of | understood,often |
R14975 | T18705 | T18704 | arg1Of | understood,poorly |
R14976 | T18705 | T18706 | arg1Of | understood,at |
R14977 | T18709 | T18706 | arg2Of | level,at |
R14978 | T18709 | T18707 | arg1Of | level,the |
R14979 | T18709 | T18708 | arg1Of | level,molecular |
R14980 | T18711 | T18710 | arg1Of | data,Our |
R14981 | T18711 | T18712 | arg1Of | data,elucidate |
R14982 | T18713 | T18712 | arg2Of | how,elucidate |
R14983 | T18714 | T18715 | arg1Of | alterations,in |
R14984 | T18714 | T18719 | arg1Of | alterations,"," |
R14985 | T18714 | T18720 | arg2Of | alterations,achieved |
R14986 | T18714 | T18732 | arg1Of | alterations,can |
R14987 | T18714 | T18733 | arg1Of | alterations,influence |
R14988 | T18718 | T18715 | arg2Of | function,in |
R14989 | T18718 | T18716 | arg1Of | function,selective |
R14990 | T18718 | T18717 | arg1Of | function,NF-κB |
R14991 | T18720 | T18721 | arg1Of | achieved,by |
R14992 | T18722 | T18725 | arg1Of | impeding,but |
R14993 | T18723 | T18722 | arg2Of | RPS3,impeding |
R14994 | T18725 | T18721 | arg2Of | but,by |
R14995 | T18725 | T18724 | arg1Of | but,"," |
R14996 | T18725 | T18726 | arg1Of | but,not |
R14997 | T18727 | T18725 | arg2Of | altering,but |
R14998 | T18730 | T18727 | arg2Of | translocation,altering |
R14999 | T18730 | T18728 | arg1Of | translocation,p65 |
R15000 | T18730 | T18729 | arg1Of | translocation,nuclear |
R15001 | T18733 | T18713 | arg1Of | influence,how |
R15002 | T18733 | T18731 | arg1Of | influence,"," |
R15003 | T18733 | T18732 | arg2Of | influence,can |
R15004 | T18735 | T18733 | arg2Of | cytokines,influence |
R15005 | T18735 | T18734 | arg1Of | cytokines,specific |
R15006 | T18735 | T18736 | arg1Of | cytokines,that |
R15007 | T18735 | T18737 | arg1Of | cytokines,affect |
R15008 | T18739 | T18738 | arg1Of | colonization,bacterial |
R15009 | T18739 | T18740 | arg1Of | colonization,"," |
R15010 | T18740 | T18743 | arg1Of | ",",and |
R15011 | T18742 | T18740 | arg2Of | diseases,"," |
R15012 | T18742 | T18741 | arg1Of | diseases,diarrhea |
R15013 | T18743 | T18737 | arg2Of | and,affect |
R15014 | T18744 | T18743 | arg2Of | mortality,and |
R15015 | T18747 | T18746 | arg2Of | be,may |
R15016 | T18748 | T18747 | arg2Of | fruitful,be |
R15017 | T18748 | T18749 | arg1Of | fruitful,in |
R15018 | T18750 | T18749 | arg2Of | attempting,in |
R15019 | T18752 | T18750 | arg2Of | understand,attempting |
R15020 | T18752 | T18751 | arg1Of | understand,to |
R15021 | T18754 | T18755 | arg1Of | infectious,and |
R15022 | T18756 | T18755 | arg2Of | autoimmune,and |
R15023 | T18757 | T18752 | arg2Of | diseases,understand |
R15024 | T18757 | T18753 | arg1Of | diseases,other |
R15025 | T18757 | T18754 | arg1Of | diseases,infectious |
R15026 | T18757 | T18756 | arg1Of | diseases,autoimmune |
R15027 | T18757 | T18758 | arg1Of | diseases,involving |
R15028 | T18759 | T18758 | arg2Of | NF-κB,involving |
R15029 | T18761 | T18745 | arg1Of | consider,It |
R15030 | T18761 | T18746 | arg1Of | consider,may |
R15031 | T18761 | T18747 | arg1Of | consider,be |
R15032 | T18761 | T18748 | arg1Of | consider,fruitful |
R15033 | T18761 | T18760 | arg1Of | consider,to |
R15034 | T18761 | T18769 | arg1Of | consider,in |
R15035 | T18763 | T18761 | arg2Of | effects,consider |
R15036 | T18763 | T18762 | arg1Of | effects,selective |
R15037 | T18763 | T18764 | arg1Of | effects,of |
R15038 | T18765 | T18764 | arg2Of | subunits,of |
R15039 | T18765 | T18767 | arg1Of | subunits,as |
R15040 | T18767 | T18766 | arg1Of | as,such |
R15041 | T18768 | T18767 | arg2Of | RPS3,as |
R15042 | T18770 | T18769 | arg2Of | addition,in |
R15043 | T18770 | T18771 | arg1Of | addition,to |
R15044 | T18774 | T18771 | arg2Of | inhibition,to |
R15045 | T18774 | T18772 | arg1Of | inhibition,global |
R15046 | T18774 | T18773 | arg1Of | inhibition,NF-κB |
bionlp-st-ge-2016-coref
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T18775 | 366-369 | Anaphor | denotes | its |
T18776 | 293-297 | Antecedent | denotes | RPS3 |
T18777 | 871-891 | Anaphor | denotes | this phosphorylation |
T18778 | 841-855 | Antecedent | denotes | phosphorylated |
T18779 | 2067-2070 | Anaphor | denotes | its |
T18780 | 2030-2034 | Antecedent | denotes | RPS3 |
R15047 | T18775 | T18776 | boundBy | its,RPS3 |
R15048 | T18777 | T18778 | boundBy | this phosphorylation,phosphorylated |
R15049 | T18779 | T18780 | boundBy | its,RPS3 |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T18827 | 11-15 | CD | denotes | RPS3 |
T18828 | 16-19 | VBD | denotes | was |
T18829 | 20-30 | RB | denotes | previously |
T18830 | 31-43 | VBN | denotes | demonstrated |
T18831 | 44-46 | TO | denotes | to |
T18832 | 47-55 | VB | denotes | function |
T18833 | 56-58 | IN | denotes | as |
T18834 | 59-61 | DT | denotes | an |
T18835 | 62-70 | JJ | denotes | integral |
T18836 | 71-78 | NN | denotes | subunit |
T18837 | 79-89 | VBG | denotes | conferring |
T18838 | 90-95 | JJ | denotes | NF-κB |
T18839 | 96-106 | JJ | denotes | regulatory |
T18840 | 107-119 | NN | denotes | specificity6 |
T18841 | 119-120 | . | denotes | . |
T18842 | 121-125 | RB | denotes | Here |
T18843 | 126-128 | PRP | denotes | we |
T18844 | 129-135 | VBD | denotes | sought |
T18845 | 136-138 | TO | denotes | to |
T18846 | 139-148 | VB | denotes | elucidate |
T18847 | 149-152 | WRB | denotes | how |
T18848 | 153-158 | JJ | denotes | NF-κB |
T18849 | 159-169 | NN | denotes | activation |
T18850 | 170-179 | VBG | denotes | signaling |
T18851 | 180-188 | VBZ | denotes | triggers |
T18852 | 189-193 | CD | denotes | RPS3 |
T18853 | 194-196 | TO | denotes | to |
T18854 | 197-208 | VB | denotes | translocate |
T18855 | 209-212 | CC | denotes | and |
T18856 | 213-224 | VB | denotes | participate |
T18857 | 225-227 | IN | denotes | in |
T18858 | 228-233 | JJ | denotes | NF-κB |
T18859 | 234-242 | NN | denotes | function |
T18860 | 243-245 | IN | denotes | in |
T18861 | 246-249 | DT | denotes | the |
T18862 | 250-257 | NN | denotes | nucleus |
T18863 | 257-258 | . | denotes | . |
T18864 | 259-261 | PRP | denotes | We |
T18865 | 262-273 | VBP | denotes | demonstrate |
T18866 | 274-278 | IN | denotes | that |
T18867 | 279-292 | JJ | denotes | IKKβ-mediated |
T18868 | 293-297 | CD | denotes | RPS3 |
T18869 | 298-302 | CD | denotes | S209 |
T18870 | 303-318 | NN | denotes | phosphorylation |
T18871 | 319-329 | VBZ | denotes | represents |
T18872 | 330-331 | DT | denotes | a |
T18873 | 332-340 | JJ | denotes | critical |
T18874 | 341-352 | NN | denotes | determinant |
T18875 | 353-355 | IN | denotes | in |
T18876 | 356-365 | VBG | denotes | governing |
T18877 | 366-369 | PRP$ | denotes | its |
T18878 | 370-377 | JJ | denotes | nuclear |
T18879 | 378-384 | NN | denotes | import |
T18880 | 385-389 | RB | denotes | thus |
T18881 | 390-399 | VBG | denotes | unveiling |
T18882 | 400-401 | DT | denotes | a |
T18883 | 402-407 | NN | denotes | novel |
T18884 | 408-417 | NN | denotes | mechanism |
T18885 | 418-424 | IN | denotes | behind |
T18886 | 425-430 | JJ | denotes | NF-κB |
T18887 | 431-441 | JJ | denotes | regulatory |
T18888 | 442-453 | NN | denotes | specificity |
T18889 | 453-454 | . | denotes | . |
T18890 | 455-459 | NNP | denotes | IKKβ |
T18891 | 460-462 | VBZ | denotes | is |
T18892 | 463-466 | DT | denotes | the |
T18893 | 467-472 | JJ | denotes | major |
T18894 | 473-479 | NN | denotes | kinase |
T18895 | 480-484 | WDT | denotes | that |
T18896 | 485-499 | VBZ | denotes | phosphorylates |
T18897 | 500-504 | NNS | denotes | IκBs |
T18898 | 505-507 | IN | denotes | in |
T18899 | 508-511 | DT | denotes | the |
T18900 | 512-521 | JJ | denotes | classical |
T18901 | 522-527 | NN | denotes | NF-κB |
T18902 | 528-535 | NN | denotes | pathway |
T18903 | 535-536 | , | denotes | , |
T18904 | 537-544 | VBG | denotes | leading |
T18905 | 545-547 | TO | denotes | to |
T18906 | 548-553 | PRP$ | denotes | their |
T18907 | 554-564 | JJ | denotes | subsequent |
T18908 | 565-578 | NN | denotes | degradation40 |
T18909 | 578-579 | . | denotes | . |
T18910 | 580-590 | RB | denotes | Strikingly |
T18911 | 590-591 | , | denotes | , |
T18912 | 592-596 | JJ | denotes | RPS3 |
T18913 | 597-606 | VBZ | denotes | possesses |
T18914 | 607-610 | RB | denotes | not |
T18915 | 611-614 | DT | denotes | any |
T18916 | 615-624 | NN | denotes | consensus |
T18917 | 625-628 | NNP | denotes | IKK |
T18918 | 629-634 | NN | denotes | motif |
T18919 | 634-635 | : | denotes | ; |
T18920 | 636-643 | RB | denotes | instead |
T18921 | 643-644 | , | denotes | , |
T18922 | 645-649 | NNP | denotes | S209 |
T18923 | 650-652 | VBZ | denotes | is |
T18924 | 653-661 | VBN | denotes | centered |
T18925 | 662-664 | IN | denotes | in |
T18926 | 665-666 | DT | denotes | a |
T18927 | 667-676 | NN | denotes | consensus |
T18928 | 677-680 | NNP | denotes | CK2 |
T18929 | 681-686 | NN | denotes | motif |
T18930 | 686-687 | . | denotes | . |
T18931 | 688-691 | DT | denotes | The |
T18932 | 692-698 | JJ | denotes | recent |
T18933 | 699-710 | NN | denotes | observation |
T18934 | 711-715 | WDT | denotes | that |
T18935 | 716-721 | JJ | denotes | human |
T18936 | 722-726 | NNP | denotes | IKKβ |
T18937 | 727-736 | VBD | denotes | displayed |
T18938 | 737-745 | JJ | denotes | CK2-like |
T18939 | 746-761 | NN | denotes | phosphorylation |
T18940 | 762-775 | CD | denotes | specificity29 |
T18941 | 776-785 | NNS | denotes | coincides |
T18942 | 786-790 | IN | denotes | with |
T18943 | 791-794 | PRP$ | denotes | our |
T18944 | 795-803 | NN | denotes | evidence |
T18945 | 804-808 | IN | denotes | that |
T18946 | 809-820 | JJ | denotes | recombinant |
T18947 | 821-825 | NNP | denotes | IKKβ |
T18948 | 825-826 | , | denotes | , |
T18949 | 827-830 | CC | denotes | but |
T18950 | 831-834 | RB | denotes | not |
T18951 | 835-839 | NNP | denotes | IKKα |
T18952 | 839-840 | , | denotes | , |
T18953 | 841-855 | VBD | denotes | phosphorylated |
T18954 | 856-860 | NNP | denotes | RPS3 |
T18955 | 860-861 | . | denotes | . |
T18956 | 862-864 | PRP | denotes | We |
T18957 | 865-870 | VBD | denotes | found |
T18958 | 871-875 | DT | denotes | this |
T18959 | 876-891 | NN | denotes | phosphorylation |
T18960 | 892-894 | VBZ | denotes | is |
T18961 | 895-896 | DT | denotes | a |
T18962 | 897-905 | JJ | denotes | critical |
T18963 | 906-916 | NN | denotes | modulation |
T18964 | 917-920 | IN | denotes | for |
T18965 | 921-925 | NNP | denotes | RPS3 |
T18966 | 926-933 | JJ | denotes | nuclear |
T18967 | 934-947 | NN | denotes | translocation |
T18968 | 948-949 | -LRB- | denotes | ( |
T18969 | 949-952 | IN | denotes | via |
T18970 | 953-963 | JJ | denotes | importin-α |
T18971 | 963-964 | -RRB- | denotes | ) |
T18972 | 965-968 | CC | denotes | and |
T18973 | 969-979 | NN | denotes | engagement |
T18974 | 980-982 | IN | denotes | in |
T18975 | 983-991 | JJ | denotes | specific |
T18976 | 992-997 | NN | denotes | NF-κB |
T18977 | 998-1011 | NN | denotes | transcription |
T18978 | 1011-1012 | . | denotes | . |
T18979 | 1013-1016 | CD | denotes | CK2 |
T18980 | 1017-1020 | VBD | denotes | was |
T18981 | 1021-1031 | RB | denotes | previously |
T18982 | 1032-1037 | VBN | denotes | shown |
T18983 | 1038-1040 | TO | denotes | to |
T18984 | 1041-1054 | VB | denotes | phosphorylate |
T18985 | 1055-1058 | NNS | denotes | p65 |
T18986 | 1059-1062 | CC | denotes | and |
T18987 | 1063-1065 | TO | denotes | to |
T18988 | 1066-1070 | NN | denotes | bind |
T18989 | 1071-1073 | TO | denotes | to |
T18990 | 1074-1077 | CC | denotes | and |
T18991 | 1078-1091 | VB | denotes | phosphorylate |
T18992 | 1092-1101 | JJ | denotes | IKKβ41-43 |
T18993 | 1101-1102 | , | denotes | , |
T18994 | 1103-1110 | RB | denotes | however |
T18995 | 1110-1111 | , | denotes | , |
T18996 | 1112-1114 | PRP | denotes | we |
T18997 | 1115-1120 | VBD | denotes | ruled |
T18998 | 1121-1124 | RP | denotes | out |
T18999 | 1125-1128 | DT | denotes | the |
T19000 | 1129-1140 | NN | denotes | possibility |
T19001 | 1141-1145 | IN | denotes | that |
T19002 | 1146-1149 | DT | denotes | the |
T19003 | 1150-1160 | JJ | denotes | IKKβ-bound |
T19004 | 1161-1164 | NN | denotes | CK2 |
T19005 | 1165-1170 | MD | denotes | could |
T19006 | 1171-1178 | VB | denotes | account |
T19007 | 1179-1182 | IN | denotes | for |
T19008 | 1183-1186 | DT | denotes | the |
T19009 | 1187-1195 | JJ | denotes | observed |
T19010 | 1196-1200 | NN | denotes | RPS3 |
T19011 | 1201-1216 | NN | denotes | phosphorylation |
T19012 | 1217-1224 | IN | denotes | because |
T19013 | 1225-1227 | DT | denotes | no |
T19014 | 1228-1231 | NN | denotes | CK2 |
T19015 | 1232-1235 | VBD | denotes | was |
T19016 | 1236-1244 | VBN | denotes | detected |
T19017 | 1245-1247 | IN | denotes | in |
T19018 | 1248-1251 | DT | denotes | the |
T19019 | 1252-1256 | NNP | denotes | IKKβ |
T19020 | 1257-1269 | NNS | denotes | preparations |
T19021 | 1270-1274 | VBD | denotes | used |
T19022 | 1275-1278 | IN | denotes | for |
T19023 | 1279-1282 | DT | denotes | the |
T19024 | 1283-1285 | IN | denotes | in |
T19025 | 1286-1291 | NN | denotes | vitro |
T19026 | 1292-1298 | NN | denotes | kinase |
T19027 | 1299-1304 | NN | denotes | assay |
T19028 | 1304-1305 | . | denotes | . |
T19029 | 1306-1313 | IN | denotes | Because |
T19030 | 1314-1318 | CD | denotes | RPS3 |
T19031 | 1319-1323 | RB | denotes | only |
T19032 | 1324-1331 | VBZ | denotes | harbors |
T19033 | 1332-1335 | DT | denotes | the |
T19034 | 1336-1339 | NNP | denotes | CK2 |
T19035 | 1340-1345 | NN | denotes | motif |
T19036 | 1346-1349 | CC | denotes | and |
T19037 | 1350-1353 | RB | denotes | not |
T19038 | 1354-1355 | DT | denotes | a |
T19039 | 1356-1367 | JJ | denotes | traditional |
T19040 | 1368-1371 | NNP | denotes | IKK |
T19041 | 1372-1377 | NN | denotes | motif |
T19042 | 1377-1378 | , | denotes | , |
T19043 | 1379-1383 | DT | denotes | this |
T19044 | 1384-1388 | JJ | denotes | RPS3 |
T19045 | 1389-1399 | JJ | denotes | regulatory |
T19046 | 1400-1408 | NN | denotes | function |
T19047 | 1409-1414 | MD | denotes | could |
T19048 | 1415-1422 | VB | denotes | explain |
T19049 | 1423-1426 | WRB | denotes | why |
T19050 | 1427-1430 | NNP | denotes | IKK |
T19051 | 1431-1438 | VBZ | denotes | harbors |
T19052 | 1439-1442 | DT | denotes | the |
T19053 | 1443-1454 | JJ | denotes | alternative |
T19054 | 1455-1464 | JJ | denotes | substrate |
T19055 | 1465-1480 | NN | denotes | phosphorylation |
T19056 | 1481-1491 | NN | denotes | capability |
T19057 | 1491-1492 | . | denotes | . |
T19058 | 1493-1497 | RBR | denotes | More |
T19059 | 1498-1509 | RB | denotes | importantly |
T19060 | 1509-1510 | , | denotes | , |
T19061 | 1511-1514 | PRP$ | denotes | our |
T19062 | 1515-1520 | NN | denotes | study |
T19063 | 1521-1524 | VBZ | denotes | has |
T19064 | 1525-1535 | VBN | denotes | elucidated |
T19065 | 1536-1539 | WRB | denotes | how |
T19066 | 1540-1544 | NNP | denotes | RPS3 |
T19067 | 1545-1547 | VBZ | denotes | is |
T19068 | 1548-1561 | RB | denotes | biochemically |
T19069 | 1562-1572 | VBN | denotes | integrated |
T19070 | 1573-1577 | IN | denotes | into |
T19071 | 1578-1583 | JJ | denotes | NF-κB |
T19072 | 1584-1594 | NN | denotes | activation |
T19073 | 1595-1604 | VBG | denotes | signaling |
T19074 | 1605-1607 | IN | denotes | in |
T19075 | 1608-1609 | DT | denotes | a |
T19076 | 1610-1616 | NN | denotes | manner |
T19077 | 1617-1621 | WDT | denotes | that |
T19078 | 1622-1624 | VBZ | denotes | is |
T19079 | 1625-1632 | JJ | denotes | pivotal |
T19080 | 1633-1636 | IN | denotes | for |
T19081 | 1637-1640 | DT | denotes | the |
T19082 | 1641-1653 | NN | denotes | pathogenesis |
T19083 | 1654-1656 | IN | denotes | of |
T19084 | 1657-1666 | NN | denotes | foodborne |
T19085 | 1667-1675 | NN | denotes | pathogen |
T19086 | 1676-1678 | NNP | denotes | E. |
T19087 | 1679-1683 | NNS | denotes | coli |
T19088 | 1684-1688 | NNP | denotes | O157 |
T19089 | 1688-1689 | : | denotes | : |
T19090 | 1689-1691 | NNP | denotes | H7 |
T19091 | 1691-1692 | . | denotes | . |
T19092 | 1693-1706 | JJ | denotes | IKKβ-mediated |
T19093 | 1707-1711 | NNP | denotes | RPS3 |
T19094 | 1712-1716 | NNP | denotes | S209 |
T19095 | 1717-1732 | NN | denotes | phosphorylation |
T19096 | 1733-1735 | VBZ | denotes | is |
T19097 | 1736-1737 | DT | denotes | a |
T19098 | 1738-1746 | JJ | denotes | critical |
T19099 | 1747-1753 | NN | denotes | target |
T19100 | 1754-1763 | VBN | denotes | modulated |
T19101 | 1764-1766 | IN | denotes | by |
T19102 | 1767-1771 | DT | denotes | this |
T19103 | 1772-1780 | NN | denotes | pathogen |
T19104 | 1781-1783 | TO | denotes | to |
T19105 | 1784-1791 | VB | denotes | subvert |
T19106 | 1792-1796 | NN | denotes | host |
T19107 | 1797-1802 | NN | denotes | NF-κB |
T19108 | 1803-1812 | VBG | denotes | signaling |
T19109 | 1812-1813 | . | denotes | . |
T19110 | 1814-1817 | DT | denotes | The |
T19111 | 1818-1827 | JJ | denotes | bacterial |
T19112 | 1828-1836 | NN | denotes | effector |
T19113 | 1837-1842 | NNP | denotes | NleH1 |
T19114 | 1843-1855 | RB | denotes | specifically |
T19115 | 1856-1861 | VBZ | denotes | binds |
T19116 | 1862-1864 | TO | denotes | to |
T19117 | 1865-1869 | CD | denotes | RPS3 |
T19118 | 1870-1874 | RB | denotes | once |
T19119 | 1875-1883 | VBD | denotes | injected |
T19120 | 1884-1888 | IN | denotes | into |
T19121 | 1889-1893 | NN | denotes | host |
T19122 | 1894-1899 | NNS | denotes | cells |
T19123 | 1900-1903 | CC | denotes | and |
T19124 | 1904-1914 | RB | denotes | profoundly |
T19125 | 1915-1925 | VBZ | denotes | suppresses |
T19126 | 1926-1931 | NNP | denotes | NF-κB |
T19127 | 1932-1935 | CC | denotes | and |
T19128 | 1936-1939 | PRP$ | denotes | its |
T19129 | 1940-1949 | JJ | denotes | attendant |
T19130 | 1950-1960 | JJ | denotes | protective |
T19131 | 1961-1967 | JJ | denotes | immune |
T19132 | 1968-1978 | NN | denotes | responses9 |
T19133 | 1978-1979 | . | denotes | . |
T19134 | 1980-1983 | PRP$ | denotes | Our |
T19135 | 1984-1988 | NNS | denotes | data |
T19136 | 1989-1992 | RB | denotes | now |
T19137 | 1993-1997 | VBP | denotes | show |
T19138 | 1998-2002 | IN | denotes | that |
T19139 | 2003-2008 | JJ | denotes | NleH1 |
T19140 | 2009-2020 | RB | denotes | selectively |
T19141 | 2021-2029 | VBZ | denotes | inhibits |
T19142 | 2030-2034 | CD | denotes | RPS3 |
T19143 | 2035-2050 | NN | denotes | phosphorylation |
T19144 | 2050-2051 | , | denotes | , |
T19145 | 2052-2056 | RB | denotes | thus |
T19146 | 2057-2066 | VBG | denotes | retarding |
T19147 | 2067-2070 | PRP$ | denotes | its |
T19148 | 2071-2078 | JJ | denotes | nuclear |
T19149 | 2079-2092 | NN | denotes | translocation |
T19150 | 2093-2096 | CC | denotes | and |
T19151 | 2097-2107 | JJ | denotes | subsequent |
T19152 | 2108-2113 | NN | denotes | NF-κB |
T19153 | 2114-2122 | NN | denotes | function |
T19154 | 2122-2123 | , | denotes | , |
T19155 | 2124-2131 | IN | denotes | without |
T19156 | 2132-2140 | VBG | denotes | altering |
T19157 | 2141-2146 | JJ | denotes | other |
T19158 | 2147-2152 | JJ | denotes | NF-κB |
T19159 | 2153-2162 | VBG | denotes | signaling |
T19160 | 2162-2163 | . | denotes | . |
T19161 | 2164-2172 | IN | denotes | Although |
T19162 | 2173-2178 | NNP | denotes | NleH1 |
T19163 | 2179-2182 | VBD | denotes | did |
T19164 | 2183-2186 | RB | denotes | not |
T19165 | 2187-2195 | RB | denotes | directly |
T19166 | 2196-2209 | VB | denotes | phosphorylate |
T19167 | 2210-2214 | NNP | denotes | IKKβ |
T19168 | 2214-2215 | , | denotes | , |
T19169 | 2216-2219 | PRP$ | denotes | its |
T19170 | 2220-2226 | NN | denotes | kinase |
T19171 | 2227-2235 | NN | denotes | activity |
T19172 | 2236-2239 | VBD | denotes | was |
T19173 | 2240-2248 | VBN | denotes | required |
T19174 | 2249-2251 | TO | denotes | to |
T19175 | 2252-2259 | VB | denotes | inhibit |
T19176 | 2260-2273 | JJ | denotes | IKKβ-mediated |
T19177 | 2274-2278 | NNP | denotes | RPS3 |
T19178 | 2279-2283 | NNP | denotes | S209 |
T19179 | 2284-2299 | NN | denotes | phosphorylation |
T19180 | 2299-2300 | . | denotes | . |
T19181 | 2301-2305 | JJ | denotes | Many |
T19182 | 2306-2314 | NNS | denotes | bacteria |
T19183 | 2315-2324 | NNS | denotes | pathogens |
T19184 | 2325-2329 | VBP | denotes | have |
T19185 | 2330-2338 | NNS | denotes | products |
T19186 | 2339-2343 | WDT | denotes | that |
T19187 | 2344-2350 | VBP | denotes | target |
T19188 | 2351-2354 | JJ | denotes | key |
T19189 | 2355-2362 | NNS | denotes | kinases |
T19190 | 2363-2365 | TO | denotes | to |
T19191 | 2366-2376 | VB | denotes | inactivate |
T19192 | 2377-2381 | PRP | denotes | them |
T19193 | 2382-2384 | IN | denotes | in |
T19194 | 2385-2389 | NN | denotes | host |
T19195 | 2390-2395 | NNS | denotes | cells |
T19196 | 2395-2396 | , | denotes | , |
T19197 | 2397-2404 | IN | denotes | whereas |
T19198 | 2405-2407 | NNP | denotes | E. |
T19199 | 2408-2412 | NNS | denotes | coli |
T19200 | 2413-2417 | NNP | denotes | O157 |
T19201 | 2417-2418 | : | denotes | : |
T19202 | 2418-2420 | NNP | denotes | H7 |
T19203 | 2421-2429 | VBN | denotes | employed |
T19204 | 2430-2435 | NNP | denotes | NleH1 |
T19205 | 2436-2438 | TO | denotes | to |
T19206 | 2439-2444 | VB | denotes | steer |
T19207 | 2445-2448 | DT | denotes | the |
T19208 | 2449-2458 | JJ | denotes | substrate |
T19209 | 2459-2470 | NN | denotes | specificity |
T19210 | 2471-2473 | IN | denotes | of |
T19211 | 2474-2478 | NNP | denotes | IKKβ |
T19212 | 2479-2483 | RB | denotes | thus |
T19213 | 2484-2496 | RB | denotes | specifically |
T19214 | 2497-2508 | VB | denotes | fine-tuning |
T19215 | 2509-2513 | NN | denotes | host |
T19216 | 2514-2519 | NN | denotes | NF-κB |
T19217 | 2520-2529 | VBG | denotes | signaling |
T19218 | 2529-2530 | . | denotes | . |
T19219 | 2531-2535 | DT | denotes | This |
T19220 | 2536-2541 | MD | denotes | could |
T19221 | 2542-2551 | VB | denotes | represent |
T19222 | 2552-2553 | DT | denotes | a |
T19223 | 2554-2559 | NN | denotes | novel |
T19224 | 2560-2568 | NN | denotes | strategy |
T19225 | 2569-2571 | TO | denotes | to |
T19226 | 2572-2581 | VB | denotes | fine-tune |
T19227 | 2582-2586 | NN | denotes | host |
T19228 | 2587-2592 | NN | denotes | NF-κB |
T19229 | 2593-2602 | VBG | denotes | signaling |
T19230 | 2603-2607 | DT | denotes | that |
T19231 | 2608-2613 | MD | denotes | could |
T19232 | 2614-2616 | VB | denotes | be |
T19233 | 2617-2623 | VBN | denotes | shared |
T19234 | 2624-2626 | IN | denotes | by |
T19235 | 2627-2632 | JJ | denotes | other |
T19236 | 2633-2642 | NNS | denotes | pathogens |
T19237 | 2642-2643 | . | denotes | . |
T19238 | 2644-2649 | DT | denotes | These |
T19239 | 2650-2654 | NNS | denotes | data |
T19240 | 2655-2662 | VBP | denotes | provide |
T19241 | 2663-2666 | JJ | denotes | new |
T19242 | 2667-2675 | NNS | denotes | insights |
T19243 | 2676-2680 | IN | denotes | into |
T19244 | 2681-2684 | DT | denotes | the |
T19245 | 2685-2691 | RB | denotes | poorly |
T19246 | 2692-2702 | VBN | denotes | understood |
T19247 | 2703-2709 | NN | denotes | action |
T19248 | 2710-2719 | NN | denotes | mechanism |
T19249 | 2720-2723 | IN | denotes | for |
T19250 | 2724-2728 | JJS | denotes | most |
T19251 | 2729-2733 | CD | denotes | T3SS |
T19252 | 2734-2743 | NNS | denotes | effectors |
T19253 | 2743-2744 | . | denotes | . |
T19254 | 2745-2750 | CD | denotes | NleH1 |
T19255 | 2751-2761 | VBZ | denotes | attenuates |
T19256 | 2762-2765 | DT | denotes | the |
T19257 | 2766-2779 | NN | denotes | transcription |
T19258 | 2780-2782 | IN | denotes | of |
T19259 | 2783-2797 | NN | denotes | RPS3-dependent |
T19260 | 2797-2798 | , | denotes | , |
T19261 | 2799-2802 | CC | denotes | but |
T19262 | 2803-2806 | RB | denotes | not |
T19263 | 2807-2810 | DT | denotes | all |
T19264 | 2810-2811 | , | denotes | , |
T19265 | 2812-2817 | JJ | denotes | NF-κB |
T19266 | 2818-2824 | NN | denotes | target |
T19267 | 2825-2830 | NNS | denotes | genes |
T19268 | 2830-2831 | , | denotes | , |
T19269 | 2832-2834 | IN | denotes | in |
T19270 | 2835-2845 | JJ | denotes | particular |
T19271 | 2846-2851 | DT | denotes | those |
T19272 | 2852-2857 | NNS | denotes | genes |
T19273 | 2858-2868 | VBN | denotes | associated |
T19274 | 2869-2873 | IN | denotes | with |
T19275 | 2874-2879 | JJ | denotes | acute |
T19276 | 2880-2895 | JJ | denotes | proinflammatory |
T19277 | 2896-2905 | NNS | denotes | responses |
T19278 | 2905-2906 | , | denotes | , |
T19279 | 2907-2916 | VBG | denotes | including |
T19280 | 2917-2920 | NNP | denotes | IL8 |
T19281 | 2921-2924 | CC | denotes | and |
T19282 | 2925-2928 | NNP | denotes | TNF |
T19283 | 2928-2929 | . | denotes | . |
T19284 | 2930-2932 | IN | denotes | In |
T19285 | 2933-2941 | NN | denotes | contrast |
T19286 | 2941-2942 | , | denotes | , |
T19287 | 2943-2948 | NNP | denotes | NleH1 |
T19288 | 2949-2953 | VBZ | denotes | does |
T19289 | 2954-2957 | RB | denotes | not |
T19290 | 2958-2963 | VB | denotes | block |
T19291 | 2964-2969 | NNP | denotes | NF-κB |
T19292 | 2970-2973 | CD | denotes | p65 |
T19293 | 2974-2981 | JJ | denotes | nuclear |
T19294 | 2982-2995 | NN | denotes | translocation |
T19295 | 2995-2996 | , | denotes | , |
T19296 | 2997-3002 | WDT | denotes | which |
T19297 | 3003-3011 | VBZ | denotes | suggests |
T19298 | 3012-3016 | IN | denotes | that |
T19299 | 3017-3024 | JJ | denotes | certain |
T19300 | 3025-3038 | JJ | denotes | p65-dependent |
T19301 | 3039-3042 | CC | denotes | but |
T19302 | 3043-3059 | JJ | denotes | RPS3-independent |
T19303 | 3060-3065 | NN | denotes | NF-κB |
T19304 | 3066-3072 | NN | denotes | target |
T19305 | 3073-3078 | NNS | denotes | genes |
T19306 | 3079-3084 | MD | denotes | might |
T19307 | 3085-3089 | RB | denotes | thus |
T19308 | 3090-3092 | VB | denotes | be |
T19309 | 3093-3103 | JJ | denotes | beneficial |
T19310 | 3104-3107 | IN | denotes | for |
T19311 | 3108-3110 | NNP | denotes | E. |
T19312 | 3111-3115 | NNS | denotes | coli |
T19313 | 3116-3120 | NNP | denotes | O157 |
T19314 | 3120-3121 | : | denotes | : |
T19315 | 3121-3123 | NNP | denotes | H7 |
T19316 | 3124-3126 | TO | denotes | to |
T19317 | 3127-3136 | VB | denotes | replicate |
T19318 | 3137-3140 | CC | denotes | and |
T19319 | 3141-3152 | VB | denotes | disseminate |
T19320 | 3153-3155 | IN | denotes | in |
T19321 | 3156-3159 | DT | denotes | the |
T19322 | 3160-3164 | NN | denotes | host |
T19323 | 3164-3165 | . | denotes | . |
T19324 | 3166-3168 | IN | denotes | By |
T19325 | 3169-3180 | RB | denotes | selectively |
T19326 | 3181-3191 | VBG | denotes | inhibiting |
T19327 | 3192-3196 | CD | denotes | RPS3 |
T19328 | 3197-3200 | CC | denotes | and |
T19329 | 3201-3204 | PRP$ | denotes | its |
T19330 | 3205-3214 | JJ | denotes | attendant |
T19331 | 3215-3220 | NN | denotes | NF-κB |
T19332 | 3221-3229 | NN | denotes | function |
T19333 | 3230-3234 | IN | denotes | with |
T19334 | 3235-3240 | NNP | denotes | NleH1 |
T19335 | 3240-3241 | , | denotes | , |
T19336 | 3242-3245 | DT | denotes | the |
T19337 | 3246-3254 | NN | denotes | pathogen |
T19338 | 3255-3263 | VBZ | denotes | achieves |
T19339 | 3264-3267 | DT | denotes | the |
T19340 | 3268-3275 | NN | denotes | ability |
T19341 | 3276-3278 | TO | denotes | to |
T19342 | 3279-3287 | VB | denotes | increase |
T19343 | 3288-3300 | NN | denotes | colonization |
T19344 | 3301-3304 | CC | denotes | and |
T19345 | 3305-3313 | NN | denotes | diarrhea |
T19346 | 3314-3317 | RB | denotes | yet |
T19347 | 3318-3326 | VBG | denotes | limiting |
T19348 | 3327-3330 | DT | denotes | the |
T19349 | 3331-3340 | NN | denotes | mortality |
T19350 | 3341-3343 | IN | denotes | of |
T19351 | 3344-3347 | DT | denotes | the |
T19352 | 3348-3352 | NN | denotes | host |
T19353 | 3352-3353 | . | denotes | . |
T19354 | 3354-3358 | DT | denotes | This |
T19355 | 3359-3368 | RB | denotes | seemingly |
T19356 | 3369-3380 | JJ | denotes | paradoxical |
T19357 | 3381-3392 | NN | denotes | combination |
T19358 | 3393-3395 | IN | denotes | of |
T19359 | 3396-3403 | NNS | denotes | effects |
T19360 | 3404-3408 | VBP | denotes | make |
T19361 | 3409-3414 | NN | denotes | sense |
T19362 | 3415-3419 | WRB | denotes | when |
T19363 | 3420-3423 | CD | denotes | one |
T19364 | 3424-3433 | VBZ | denotes | considers |
T19365 | 3434-3438 | IN | denotes | that |
T19366 | 3439-3448 | VBN | denotes | increased |
T19367 | 3449-3458 | JJ | denotes | bacterial |
T19368 | 3459-3463 | NN | denotes | load |
T19369 | 3464-3467 | CC | denotes | and |
T19370 | 3468-3476 | NN | denotes | diarrhea |
T19371 | 3477-3485 | RB | denotes | together |
T19372 | 3486-3490 | IN | denotes | with |
T19373 | 3491-3499 | NN | denotes | survival |
T19374 | 3500-3502 | IN | denotes | of |
T19375 | 3503-3506 | DT | denotes | the |
T19376 | 3507-3515 | JJ | denotes | infected |
T19377 | 3516-3520 | NN | denotes | host |
T19378 | 3521-3526 | MD | denotes | would |
T19379 | 3527-3534 | VB | denotes | promote |
T19380 | 3535-3538 | DT | denotes | the |
T19381 | 3539-3548 | VBG | denotes | spreading |
T19382 | 3549-3551 | IN | denotes | of |
T19383 | 3552-3555 | DT | denotes | the |
T19384 | 3556-3564 | NNS | denotes | bacteria |
T19385 | 3565-3570 | IN | denotes | among |
T19386 | 3571-3572 | DT | denotes | a |
T19387 | 3573-3583 | NN | denotes | population |
T19388 | 3584-3586 | IN | denotes | of |
T19389 | 3587-3598 | JJ | denotes | susceptible |
T19390 | 3599-3610 | NNS | denotes | individuals |
T19391 | 3610-3611 | . | denotes | . |
T19392 | 3612-3616 | JJ | denotes | Such |
T19393 | 3617-3624 | NN | denotes | complex |
T19394 | 3625-3628 | CC | denotes | and |
T19395 | 3629-3640 | JJ | denotes | paradoxical |
T19396 | 3641-3653 | JJ | denotes | pathological |
T19397 | 3654-3661 | NNS | denotes | effects |
T19398 | 3662-3666 | WDT | denotes | that |
T19399 | 3667-3676 | VBP | denotes | influence |
T19400 | 3677-3680 | DT | denotes | the |
T19401 | 3681-3687 | NN | denotes | spread |
T19402 | 3688-3690 | IN | denotes | of |
T19403 | 3691-3698 | NN | denotes | disease |
T19404 | 3699-3702 | VBP | denotes | are |
T19405 | 3703-3708 | RB | denotes | often |
T19406 | 3709-3715 | RB | denotes | poorly |
T19407 | 3716-3726 | VBN | denotes | understood |
T19408 | 3727-3729 | IN | denotes | at |
T19409 | 3730-3733 | DT | denotes | the |
T19410 | 3734-3743 | JJ | denotes | molecular |
T19411 | 3744-3749 | NN | denotes | level |
T19412 | 3749-3750 | . | denotes | . |
T19413 | 3751-3754 | PRP$ | denotes | Our |
T19414 | 3755-3759 | NNS | denotes | data |
T19415 | 3760-3769 | VB | denotes | elucidate |
T19416 | 3770-3773 | WRB | denotes | how |
T19417 | 3774-3785 | NNS | denotes | alterations |
T19418 | 3786-3788 | IN | denotes | in |
T19419 | 3789-3798 | JJ | denotes | selective |
T19420 | 3799-3804 | NN | denotes | NF-κB |
T19421 | 3805-3813 | NN | denotes | function |
T19422 | 3813-3814 | , | denotes | , |
T19423 | 3815-3823 | VBN | denotes | achieved |
T19424 | 3824-3826 | IN | denotes | by |
T19425 | 3827-3835 | VBG | denotes | impeding |
T19426 | 3836-3840 | NNP | denotes | RPS3 |
T19427 | 3840-3841 | , | denotes | , |
T19428 | 3842-3845 | CC | denotes | but |
T19429 | 3846-3849 | RB | denotes | not |
T19430 | 3850-3858 | VBG | denotes | altering |
T19431 | 3859-3862 | CD | denotes | p65 |
T19432 | 3863-3870 | JJ | denotes | nuclear |
T19433 | 3871-3884 | NN | denotes | translocation |
T19434 | 3884-3885 | , | denotes | , |
T19435 | 3886-3889 | MD | denotes | can |
T19436 | 3890-3899 | VB | denotes | influence |
T19437 | 3900-3908 | JJ | denotes | specific |
T19438 | 3909-3918 | NNS | denotes | cytokines |
T19439 | 3919-3923 | WDT | denotes | that |
T19440 | 3924-3930 | VBP | denotes | affect |
T19441 | 3931-3940 | JJ | denotes | bacterial |
T19442 | 3941-3953 | NN | denotes | colonization |
T19443 | 3953-3954 | , | denotes | , |
T19444 | 3955-3963 | NN | denotes | diarrhea |
T19445 | 3964-3972 | NNS | denotes | diseases |
T19446 | 3973-3976 | CC | denotes | and |
T19447 | 3977-3986 | NN | denotes | mortality |
T19448 | 3986-3987 | . | denotes | . |
T19449 | 3988-3990 | PRP | denotes | It |
T19450 | 3991-3994 | MD | denotes | may |
T19451 | 3995-3997 | VB | denotes | be |
T19452 | 3998-4006 | JJ | denotes | fruitful |
T19453 | 4007-4009 | IN | denotes | in |
T19454 | 4010-4020 | VBG | denotes | attempting |
T19455 | 4021-4023 | TO | denotes | to |
T19456 | 4024-4034 | VB | denotes | understand |
T19457 | 4035-4040 | JJ | denotes | other |
T19458 | 4041-4051 | JJ | denotes | infectious |
T19459 | 4052-4055 | CC | denotes | and |
T19460 | 4056-4066 | JJ | denotes | autoimmune |
T19461 | 4067-4075 | NNS | denotes | diseases |
T19462 | 4076-4085 | VBG | denotes | involving |
T19463 | 4086-4091 | NN | denotes | NF-κB |
T19464 | 4092-4094 | TO | denotes | to |
T19465 | 4095-4103 | VB | denotes | consider |
T19466 | 4104-4113 | JJ | denotes | selective |
T19467 | 4114-4121 | NNS | denotes | effects |
T19468 | 4122-4124 | IN | denotes | of |
T19469 | 4125-4133 | NNS | denotes | subunits |
T19470 | 4134-4138 | JJ | denotes | such |
T19471 | 4139-4141 | IN | denotes | as |
T19472 | 4142-4146 | CD | denotes | RPS3 |
T19473 | 4147-4149 | IN | denotes | in |
T19474 | 4150-4158 | NN | denotes | addition |
T19475 | 4159-4161 | TO | denotes | to |
T19476 | 4162-4168 | JJ | denotes | global |
T19477 | 4169-4174 | NN | denotes | NF-κB |
T19478 | 4175-4185 | NN | denotes | inhibition |
T19479 | 4185-4186 | . | denotes | . |
R15050 | T18827 | T18830 | nsubjpass | RPS3,demonstrated |
R15051 | T18828 | T18830 | auxpass | was,demonstrated |
R15052 | T18829 | T18830 | advmod | previously,demonstrated |
R15053 | T18830 | T18830 | ROOT | demonstrated,demonstrated |
R15054 | T18831 | T18832 | aux | to,function |
R15055 | T18832 | T18830 | xcomp | function,demonstrated |
R15056 | T18833 | T18832 | prep | as,function |
R15057 | T18834 | T18836 | det | an,subunit |
R15058 | T18835 | T18836 | amod | integral,subunit |
R15059 | T18836 | T18833 | pobj | subunit,as |
R15060 | T18837 | T18836 | acl | conferring,subunit |
R15061 | T18838 | T18840 | amod | NF-κB,specificity6 |
R15062 | T18839 | T18840 | amod | regulatory,specificity6 |
R15063 | T18840 | T18837 | dobj | specificity6,conferring |
R15064 | T18841 | T18830 | punct | .,demonstrated |
R15065 | T18842 | T18844 | advmod | Here,sought |
R15066 | T18843 | T18844 | nsubj | we,sought |
R15067 | T18844 | T18844 | ROOT | sought,sought |
R15068 | T18845 | T18846 | aux | to,elucidate |
R15069 | T18846 | T18844 | xcomp | elucidate,sought |
R15070 | T18847 | T18851 | advmod | how,triggers |
R15071 | T18848 | T18849 | amod | NF-κB,activation |
R15072 | T18849 | T18851 | nsubj | activation,triggers |
R15073 | T18850 | T18851 | nsubj | signaling,triggers |
R15074 | T18851 | T18846 | ccomp | triggers,elucidate |
R15075 | T18852 | T18851 | dobj | RPS3,triggers |
R15076 | T18853 | T18854 | aux | to,translocate |
R15077 | T18854 | T18846 | advcl | translocate,elucidate |
R15078 | T18855 | T18854 | cc | and,translocate |
R15079 | T18856 | T18854 | conj | participate,translocate |
R15080 | T18857 | T18856 | prep | in,participate |
R15081 | T18858 | T18859 | amod | NF-κB,function |
R15082 | T18859 | T18857 | pobj | function,in |
R15083 | T18860 | T18859 | prep | in,function |
R15084 | T18861 | T18862 | det | the,nucleus |
R15085 | T18862 | T18860 | pobj | nucleus,in |
R15086 | T18863 | T18844 | punct | .,sought |
R15087 | T18864 | T18865 | nsubj | We,demonstrate |
R15088 | T18865 | T18865 | ROOT | demonstrate,demonstrate |
R15089 | T18866 | T18871 | mark | that,represents |
R15090 | T18867 | T18871 | advmod | IKKβ-mediated,represents |
R15091 | T18868 | T18870 | nummod | RPS3,phosphorylation |
R15092 | T18869 | T18870 | nummod | S209,phosphorylation |
R15093 | T18870 | T18871 | nsubj | phosphorylation,represents |
R15094 | T18871 | T18865 | ccomp | represents,demonstrate |
R15095 | T18872 | T18874 | det | a,determinant |
R15096 | T18873 | T18874 | amod | critical,determinant |
R15097 | T18874 | T18871 | dobj | determinant,represents |
R15098 | T18875 | T18874 | prep | in,determinant |
R15099 | T18876 | T18875 | pcomp | governing,in |
R15100 | T18877 | T18879 | poss | its,import |
R15101 | T18878 | T18879 | amod | nuclear,import |
R15102 | T18879 | T18876 | dobj | import,governing |
R15103 | T18880 | T18881 | advmod | thus,unveiling |
R15104 | T18881 | T18871 | advcl | unveiling,represents |
R15105 | T18882 | T18884 | det | a,mechanism |
R15106 | T18883 | T18884 | compound | novel,mechanism |
R15107 | T18884 | T18881 | dobj | mechanism,unveiling |
R15108 | T18885 | T18884 | prep | behind,mechanism |
R15109 | T18886 | T18888 | amod | NF-κB,specificity |
R15110 | T18887 | T18888 | amod | regulatory,specificity |
R15111 | T18888 | T18885 | pobj | specificity,behind |
R15112 | T18889 | T18865 | punct | .,demonstrate |
R15113 | T18890 | T18891 | nsubj | IKKβ,is |
R15114 | T18891 | T18891 | ROOT | is,is |
R15115 | T18892 | T18894 | det | the,kinase |
R15116 | T18893 | T18894 | amod | major,kinase |
R15117 | T18894 | T18891 | attr | kinase,is |
R15118 | T18895 | T18896 | nsubj | that,phosphorylates |
R15119 | T18896 | T18894 | relcl | phosphorylates,kinase |
R15120 | T18897 | T18896 | dobj | IκBs,phosphorylates |
R15121 | T18898 | T18897 | prep | in,IκBs |
R15122 | T18899 | T18902 | det | the,pathway |
R15123 | T18900 | T18902 | amod | classical,pathway |
R15124 | T18901 | T18902 | compound | NF-κB,pathway |
R15125 | T18902 | T18898 | pobj | pathway,in |
R15126 | T18903 | T18891 | punct | ",",is |
R15127 | T18904 | T18891 | advcl | leading,is |
R15128 | T18905 | T18904 | prep | to,leading |
R15129 | T18906 | T18908 | poss | their,degradation40 |
R15130 | T18907 | T18908 | amod | subsequent,degradation40 |
R15131 | T18908 | T18905 | pobj | degradation40,to |
R15132 | T18909 | T18891 | punct | .,is |
R15133 | T18910 | T18913 | advmod | Strikingly,possesses |
R15134 | T18911 | T18913 | punct | ",",possesses |
R15135 | T18912 | T18913 | nsubj | RPS3,possesses |
R15136 | T18913 | T18924 | ccomp | possesses,centered |
R15137 | T18914 | T18913 | neg | not,possesses |
R15138 | T18915 | T18918 | det | any,motif |
R15139 | T18916 | T18918 | compound | consensus,motif |
R15140 | T18917 | T18918 | compound | IKK,motif |
R15141 | T18918 | T18913 | dobj | motif,possesses |
R15142 | T18919 | T18924 | punct | ;,centered |
R15143 | T18920 | T18924 | advmod | instead,centered |
R15144 | T18921 | T18924 | punct | ",",centered |
R15145 | T18922 | T18924 | nsubjpass | S209,centered |
R15146 | T18923 | T18924 | auxpass | is,centered |
R15147 | T18924 | T18924 | ROOT | centered,centered |
R15148 | T18925 | T18924 | prep | in,centered |
R15149 | T18926 | T18929 | det | a,motif |
R15150 | T18927 | T18929 | compound | consensus,motif |
R15151 | T18928 | T18929 | compound | CK2,motif |
R15152 | T18929 | T18925 | pobj | motif,in |
R15153 | T18930 | T18924 | punct | .,centered |
R15154 | T18931 | T18933 | det | The,observation |
R15155 | T18932 | T18933 | amod | recent,observation |
R15156 | T18933 | T18933 | ROOT | observation,observation |
R15157 | T18934 | T18937 | dobj | that,displayed |
R15158 | T18935 | T18936 | compound | human,IKKβ |
R15159 | T18936 | T18937 | nsubj | IKKβ,displayed |
R15160 | T18937 | T18933 | relcl | displayed,observation |
R15161 | T18938 | T18939 | amod | CK2-like,phosphorylation |
R15162 | T18939 | T18933 | appos | phosphorylation,observation |
R15163 | T18940 | T18941 | nummod | specificity29,coincides |
R15164 | T18941 | T18933 | appos | coincides,observation |
R15165 | T18942 | T18941 | prep | with,coincides |
R15166 | T18943 | T18944 | poss | our,evidence |
R15167 | T18944 | T18942 | pobj | evidence,with |
R15168 | T18945 | T18944 | mark | that,evidence |
R15169 | T18946 | T18947 | compound | recombinant,IKKβ |
R15170 | T18947 | T18945 | nsubj | IKKβ,that |
R15171 | T18948 | T18947 | punct | ",",IKKβ |
R15172 | T18949 | T18947 | cc | but,IKKβ |
R15173 | T18950 | T18949 | neg | not,but |
R15174 | T18951 | T18947 | conj | IKKα,IKKβ |
R15175 | T18952 | T18953 | punct | ",",phosphorylated |
R15176 | T18953 | T18954 | compound | phosphorylated,RPS3 |
R15177 | T18954 | T18947 | conj | RPS3,IKKβ |
R15178 | T18955 | T18933 | punct | .,observation |
R15179 | T18956 | T18957 | nsubj | We,found |
R15180 | T18957 | T18957 | ROOT | found,found |
R15181 | T18958 | T18959 | det | this,phosphorylation |
R15182 | T18959 | T18960 | nsubj | phosphorylation,is |
R15183 | T18960 | T18957 | ccomp | is,found |
R15184 | T18961 | T18963 | det | a,modulation |
R15185 | T18962 | T18963 | amod | critical,modulation |
R15186 | T18963 | T18960 | attr | modulation,is |
R15187 | T18964 | T18963 | prep | for,modulation |
R15188 | T18965 | T18967 | nmod | RPS3,translocation |
R15189 | T18966 | T18967 | amod | nuclear,translocation |
R15190 | T18967 | T18964 | pobj | translocation,for |
R15191 | T18968 | T18967 | punct | (,translocation |
R15192 | T18969 | T18967 | prep | via,translocation |
R15193 | T18970 | T18969 | pobj | importin-α,via |
R15194 | T18971 | T18967 | punct | ),translocation |
R15195 | T18972 | T18967 | cc | and,translocation |
R15196 | T18973 | T18963 | conj | engagement,modulation |
R15197 | T18974 | T18973 | prep | in,engagement |
R15198 | T18975 | T18977 | amod | specific,transcription |
R15199 | T18976 | T18977 | compound | NF-κB,transcription |
R15200 | T18977 | T18974 | pobj | transcription,in |
R15201 | T18978 | T18957 | punct | .,found |
R15202 | T18979 | T18982 | nsubjpass | CK2,shown |
R15203 | T18980 | T18982 | auxpass | was,shown |
R15204 | T18981 | T18982 | advmod | previously,shown |
R15205 | T18982 | T18982 | ROOT | shown,shown |
R15206 | T18983 | T18984 | aux | to,phosphorylate |
R15207 | T18984 | T18982 | xcomp | phosphorylate,shown |
R15208 | T18985 | T18984 | dobj | p65,phosphorylate |
R15209 | T18986 | T18984 | cc | and,phosphorylate |
R15210 | T18987 | T18988 | aux | to,bind |
R15211 | T18988 | T18982 | advcl | bind,shown |
R15212 | T18989 | T18988 | prep | to,bind |
R15213 | T18990 | T18988 | cc | and,bind |
R15214 | T18991 | T18992 | compound | phosphorylate,IKKβ41-43 |
R15215 | T18992 | T18988 | conj | IKKβ41-43,bind |
R15216 | T18993 | T18997 | punct | ",",ruled |
R15217 | T18994 | T18997 | advmod | however,ruled |
R15218 | T18995 | T18997 | punct | ",",ruled |
R15219 | T18996 | T18997 | nsubj | we,ruled |
R15220 | T18997 | T18982 | advcl | ruled,shown |
R15221 | T18998 | T18997 | prt | out,ruled |
R15222 | T18999 | T19000 | det | the,possibility |
R15223 | T19000 | T18997 | dobj | possibility,ruled |
R15224 | T19001 | T19006 | mark | that,account |
R15225 | T19002 | T19004 | det | the,CK2 |
R15226 | T19003 | T19004 | amod | IKKβ-bound,CK2 |
R15227 | T19004 | T19006 | nsubj | CK2,account |
R15228 | T19005 | T19006 | aux | could,account |
R15229 | T19006 | T19000 | acl | account,possibility |
R15230 | T19007 | T19006 | prep | for,account |
R15231 | T19008 | T19011 | det | the,phosphorylation |
R15232 | T19009 | T19011 | amod | observed,phosphorylation |
R15233 | T19010 | T19011 | compound | RPS3,phosphorylation |
R15234 | T19011 | T19007 | pobj | phosphorylation,for |
R15235 | T19012 | T19016 | mark | because,detected |
R15236 | T19013 | T19014 | det | no,CK2 |
R15237 | T19014 | T19016 | nsubjpass | CK2,detected |
R15238 | T19015 | T19016 | auxpass | was,detected |
R15239 | T19016 | T19006 | advcl | detected,account |
R15240 | T19017 | T19016 | prep | in,detected |
R15241 | T19018 | T19020 | det | the,preparations |
R15242 | T19019 | T19020 | compound | IKKβ,preparations |
R15243 | T19020 | T19017 | pobj | preparations,in |
R15244 | T19021 | T19020 | acl | used,preparations |
R15245 | T19022 | T19021 | prep | for,used |
R15246 | T19023 | T19027 | det | the,assay |
R15247 | T19024 | T19027 | nmod | in,assay |
R15248 | T19025 | T19027 | amod | vitro,assay |
R15249 | T19026 | T19027 | compound | kinase,assay |
R15250 | T19027 | T19022 | pobj | assay,for |
R15251 | T19028 | T18982 | punct | .,shown |
R15252 | T19029 | T19032 | mark | Because,harbors |
R15253 | T19030 | T19032 | nsubj | RPS3,harbors |
R15254 | T19031 | T19032 | advmod | only,harbors |
R15255 | T19032 | T19048 | advcl | harbors,explain |
R15256 | T19033 | T19035 | det | the,motif |
R15257 | T19034 | T19035 | compound | CK2,motif |
R15258 | T19035 | T19032 | dobj | motif,harbors |
R15259 | T19036 | T19035 | cc | and,motif |
R15260 | T19037 | T19041 | neg | not,motif |
R15261 | T19038 | T19041 | det | a,motif |
R15262 | T19039 | T19041 | amod | traditional,motif |
R15263 | T19040 | T19041 | compound | IKK,motif |
R15264 | T19041 | T19035 | conj | motif,motif |
R15265 | T19042 | T19048 | punct | ",",explain |
R15266 | T19043 | T19046 | det | this,function |
R15267 | T19044 | T19046 | amod | RPS3,function |
R15268 | T19045 | T19046 | amod | regulatory,function |
R15269 | T19046 | T19048 | nsubj | function,explain |
R15270 | T19047 | T19048 | aux | could,explain |
R15271 | T19048 | T19048 | ROOT | explain,explain |
R15272 | T19049 | T19051 | advmod | why,harbors |
R15273 | T19050 | T19051 | nsubj | IKK,harbors |
R15274 | T19051 | T19048 | ccomp | harbors,explain |
R15275 | T19052 | T19056 | det | the,capability |
R15276 | T19053 | T19056 | amod | alternative,capability |
R15277 | T19054 | T19056 | compound | substrate,capability |
R15278 | T19055 | T19056 | compound | phosphorylation,capability |
R15279 | T19056 | T19051 | dobj | capability,harbors |
R15280 | T19057 | T19048 | punct | .,explain |
R15281 | T19058 | T19059 | advmod | More,importantly |
R15282 | T19059 | T19064 | advmod | importantly,elucidated |
R15283 | T19060 | T19064 | punct | ",",elucidated |
R15284 | T19061 | T19062 | poss | our,study |
R15285 | T19062 | T19064 | nsubj | study,elucidated |
R15286 | T19063 | T19064 | aux | has,elucidated |
R15287 | T19064 | T19064 | ROOT | elucidated,elucidated |
R15288 | T19065 | T19069 | advmod | how,integrated |
R15289 | T19066 | T19069 | nsubjpass | RPS3,integrated |
R15290 | T19067 | T19069 | auxpass | is,integrated |
R15291 | T19068 | T19069 | advmod | biochemically,integrated |
R15292 | T19069 | T19064 | ccomp | integrated,elucidated |
R15293 | T19070 | T19069 | prep | into,integrated |
R15294 | T19071 | T19072 | amod | NF-κB,activation |
R15295 | T19072 | T19070 | pobj | activation,into |
R15296 | T19073 | T19069 | advcl | signaling,integrated |
R15297 | T19074 | T19073 | prep | in,signaling |
R15298 | T19075 | T19076 | det | a,manner |
R15299 | T19076 | T19074 | pobj | manner,in |
R15300 | T19077 | T19078 | nsubj | that,is |
R15301 | T19078 | T19076 | relcl | is,manner |
R15302 | T19079 | T19078 | acomp | pivotal,is |
R15303 | T19080 | T19079 | prep | for,pivotal |
R15304 | T19081 | T19082 | det | the,pathogenesis |
R15305 | T19082 | T19080 | pobj | pathogenesis,for |
R15306 | T19083 | T19082 | prep | of,pathogenesis |
R15307 | T19084 | T19087 | compound | foodborne,coli |
R15308 | T19085 | T19087 | compound | pathogen,coli |
R15309 | T19086 | T19087 | compound | E.,coli |
R15310 | T19087 | T19088 | compound | coli,O157 |
R15311 | T19088 | T19083 | pobj | O157,of |
R15312 | T19089 | T19082 | punct | :,pathogenesis |
R15313 | T19090 | T19082 | appos | H7,pathogenesis |
R15314 | T19091 | T19064 | punct | .,elucidated |
R15315 | T19092 | T19095 | amod | IKKβ-mediated,phosphorylation |
R15316 | T19093 | T19095 | compound | RPS3,phosphorylation |
R15317 | T19094 | T19095 | compound | S209,phosphorylation |
R15318 | T19095 | T19096 | nsubj | phosphorylation,is |
R15319 | T19096 | T19096 | ROOT | is,is |
R15320 | T19097 | T19099 | det | a,target |
R15321 | T19098 | T19099 | amod | critical,target |
R15322 | T19099 | T19096 | attr | target,is |
R15323 | T19100 | T19099 | acl | modulated,target |
R15324 | T19101 | T19100 | agent | by,modulated |
R15325 | T19102 | T19103 | det | this,pathogen |
R15326 | T19103 | T19101 | pobj | pathogen,by |
R15327 | T19104 | T19105 | aux | to,subvert |
R15328 | T19105 | T19100 | advcl | subvert,modulated |
R15329 | T19106 | T19105 | dobj | host,subvert |
R15330 | T19107 | T19108 | compound | NF-κB,signaling |
R15331 | T19108 | T19096 | advcl | signaling,is |
R15332 | T19109 | T19096 | punct | .,is |
R15333 | T19110 | T19115 | det | The,binds |
R15334 | T19111 | T19112 | amod | bacterial,effector |
R15335 | T19112 | T19115 | nsubj | effector,binds |
R15336 | T19113 | T19112 | appos | NleH1,effector |
R15337 | T19114 | T19115 | advmod | specifically,binds |
R15338 | T19115 | T19119 | nsubj | binds,injected |
R15339 | T19116 | T19115 | prep | to,binds |
R15340 | T19117 | T19116 | pobj | RPS3,to |
R15341 | T19118 | T19119 | advmod | once,injected |
R15342 | T19119 | T19119 | ROOT | injected,injected |
R15343 | T19120 | T19119 | prep | into,injected |
R15344 | T19121 | T19122 | compound | host,cells |
R15345 | T19122 | T19120 | pobj | cells,into |
R15346 | T19123 | T19119 | cc | and,injected |
R15347 | T19124 | T19125 | advmod | profoundly,suppresses |
R15348 | T19125 | T19119 | conj | suppresses,injected |
R15349 | T19126 | T19125 | dobj | NF-κB,suppresses |
R15350 | T19127 | T19126 | cc | and,NF-κB |
R15351 | T19128 | T19132 | poss | its,responses9 |
R15352 | T19129 | T19132 | amod | attendant,responses9 |
R15353 | T19130 | T19132 | amod | protective,responses9 |
R15354 | T19131 | T19132 | amod | immune,responses9 |
R15355 | T19132 | T19126 | conj | responses9,NF-κB |
R15356 | T19133 | T19119 | punct | .,injected |
R15357 | T19134 | T19135 | poss | Our,data |
R15358 | T19135 | T19137 | nsubj | data,show |
R15359 | T19136 | T19137 | advmod | now,show |
R15360 | T19137 | T19137 | ROOT | show,show |
R15361 | T19138 | T19141 | mark | that,inhibits |
R15362 | T19139 | T19141 | nsubj | NleH1,inhibits |
R15363 | T19140 | T19141 | advmod | selectively,inhibits |
R15364 | T19141 | T19137 | ccomp | inhibits,show |
R15365 | T19142 | T19143 | nummod | RPS3,phosphorylation |
R15366 | T19143 | T19141 | dobj | phosphorylation,inhibits |
R15367 | T19144 | T19141 | punct | ",",inhibits |
R15368 | T19145 | T19146 | advmod | thus,retarding |
R15369 | T19146 | T19141 | advcl | retarding,inhibits |
R15370 | T19147 | T19149 | poss | its,translocation |
R15371 | T19148 | T19149 | amod | nuclear,translocation |
R15372 | T19149 | T19146 | dobj | translocation,retarding |
R15373 | T19150 | T19149 | cc | and,translocation |
R15374 | T19151 | T19153 | amod | subsequent,function |
R15375 | T19152 | T19153 | compound | NF-κB,function |
R15376 | T19153 | T19149 | conj | function,translocation |
R15377 | T19154 | T19146 | punct | ",",retarding |
R15378 | T19155 | T19146 | prep | without,retarding |
R15379 | T19156 | T19155 | pcomp | altering,without |
R15380 | T19157 | T19159 | amod | other,signaling |
R15381 | T19158 | T19159 | amod | NF-κB,signaling |
R15382 | T19159 | T19141 | advcl | signaling,inhibits |
R15383 | T19160 | T19137 | punct | .,show |
R15384 | T19161 | T19166 | mark | Although,phosphorylate |
R15385 | T19162 | T19166 | nsubj | NleH1,phosphorylate |
R15386 | T19163 | T19166 | aux | did,phosphorylate |
R15387 | T19164 | T19166 | neg | not,phosphorylate |
R15388 | T19165 | T19166 | advmod | directly,phosphorylate |
R15389 | T19166 | T19173 | advcl | phosphorylate,required |
R15390 | T19167 | T19166 | dobj | IKKβ,phosphorylate |
R15391 | T19168 | T19173 | punct | ",",required |
R15392 | T19169 | T19171 | poss | its,activity |
R15393 | T19170 | T19171 | compound | kinase,activity |
R15394 | T19171 | T19173 | nsubjpass | activity,required |
R15395 | T19172 | T19173 | auxpass | was,required |
R15396 | T19173 | T19173 | ROOT | required,required |
R15397 | T19174 | T19175 | aux | to,inhibit |
R15398 | T19175 | T19173 | advcl | inhibit,required |
R15399 | T19176 | T19179 | amod | IKKβ-mediated,phosphorylation |
R15400 | T19177 | T19179 | compound | RPS3,phosphorylation |
R15401 | T19178 | T19179 | compound | S209,phosphorylation |
R15402 | T19179 | T19175 | dobj | phosphorylation,inhibit |
R15403 | T19180 | T19173 | punct | .,required |
R15404 | T19181 | T19182 | amod | Many,bacteria |
R15405 | T19182 | T19183 | compound | bacteria,pathogens |
R15406 | T19183 | T19184 | nsubj | pathogens,have |
R15407 | T19184 | T19184 | ROOT | have,have |
R15408 | T19185 | T19184 | dobj | products,have |
R15409 | T19186 | T19187 | nsubj | that,target |
R15410 | T19187 | T19185 | relcl | target,products |
R15411 | T19188 | T19189 | amod | key,kinases |
R15412 | T19189 | T19187 | dobj | kinases,target |
R15413 | T19190 | T19191 | aux | to,inactivate |
R15414 | T19191 | T19187 | advcl | inactivate,target |
R15415 | T19192 | T19191 | dobj | them,inactivate |
R15416 | T19193 | T19191 | prep | in,inactivate |
R15417 | T19194 | T19195 | compound | host,cells |
R15418 | T19195 | T19193 | pobj | cells,in |
R15419 | T19196 | T19184 | punct | ",",have |
R15420 | T19197 | T19203 | mark | whereas,employed |
R15421 | T19198 | T19200 | compound | E.,O157 |
R15422 | T19199 | T19200 | compound | coli,O157 |
R15423 | T19200 | T19203 | nsubj | O157,employed |
R15424 | T19201 | T19200 | punct | :,O157 |
R15425 | T19202 | T19203 | nsubj | H7,employed |
R15426 | T19203 | T19184 | advcl | employed,have |
R15427 | T19204 | T19203 | dobj | NleH1,employed |
R15428 | T19205 | T19206 | aux | to,steer |
R15429 | T19206 | T19203 | advcl | steer,employed |
R15430 | T19207 | T19209 | det | the,specificity |
R15431 | T19208 | T19209 | compound | substrate,specificity |
R15432 | T19209 | T19206 | dobj | specificity,steer |
R15433 | T19210 | T19209 | prep | of,specificity |
R15434 | T19211 | T19210 | pobj | IKKβ,of |
R15435 | T19212 | T19214 | advmod | thus,fine-tuning |
R15436 | T19213 | T19214 | advmod | specifically,fine-tuning |
R15437 | T19214 | T19215 | advmod | fine-tuning,host |
R15438 | T19215 | T19217 | dep | host,signaling |
R15439 | T19216 | T19217 | compound | NF-κB,signaling |
R15440 | T19217 | T19203 | advcl | signaling,employed |
R15441 | T19218 | T19184 | punct | .,have |
R15442 | T19219 | T19221 | nsubj | This,represent |
R15443 | T19220 | T19221 | aux | could,represent |
R15444 | T19221 | T19221 | ROOT | represent,represent |
R15445 | T19222 | T19224 | det | a,strategy |
R15446 | T19223 | T19224 | compound | novel,strategy |
R15447 | T19224 | T19221 | dobj | strategy,represent |
R15448 | T19225 | T19226 | aux | to,fine-tune |
R15449 | T19226 | T19224 | acl | fine-tune,strategy |
R15450 | T19227 | T19228 | compound | host,NF-κB |
R15451 | T19228 | T19226 | dobj | NF-κB,fine-tune |
R15452 | T19229 | T19221 | advcl | signaling,represent |
R15453 | T19230 | T19233 | nsubjpass | that,shared |
R15454 | T19231 | T19233 | aux | could,shared |
R15455 | T19232 | T19233 | auxpass | be,shared |
R15456 | T19233 | T19229 | ccomp | shared,signaling |
R15457 | T19234 | T19233 | agent | by,shared |
R15458 | T19235 | T19236 | amod | other,pathogens |
R15459 | T19236 | T19234 | pobj | pathogens,by |
R15460 | T19237 | T19221 | punct | .,represent |
R15461 | T19238 | T19239 | det | These,data |
R15462 | T19239 | T19240 | nsubj | data,provide |
R15463 | T19240 | T19240 | ROOT | provide,provide |
R15464 | T19241 | T19242 | amod | new,insights |
R15465 | T19242 | T19240 | dobj | insights,provide |
R15466 | T19243 | T19242 | prep | into,insights |
R15467 | T19244 | T19248 | det | the,mechanism |
R15468 | T19245 | T19246 | advmod | poorly,understood |
R15469 | T19246 | T19248 | amod | understood,mechanism |
R15470 | T19247 | T19248 | compound | action,mechanism |
R15471 | T19248 | T19243 | pobj | mechanism,into |
R15472 | T19249 | T19240 | prep | for,provide |
R15473 | T19250 | T19252 | amod | most,effectors |
R15474 | T19251 | T19252 | nummod | T3SS,effectors |
R15475 | T19252 | T19249 | pobj | effectors,for |
R15476 | T19253 | T19240 | punct | .,provide |
R15477 | T19254 | T19255 | nummod | NleH1,attenuates |
R15478 | T19255 | T19255 | ROOT | attenuates,attenuates |
R15479 | T19256 | T19257 | det | the,transcription |
R15480 | T19257 | T19255 | dobj | transcription,attenuates |
R15481 | T19258 | T19257 | prep | of,transcription |
R15482 | T19259 | T19258 | pobj | RPS3-dependent,of |
R15483 | T19260 | T19255 | punct | ",",attenuates |
R15484 | T19261 | T19255 | cc | but,attenuates |
R15485 | T19262 | T19263 | neg | not,all |
R15486 | T19263 | T19255 | conj | all,attenuates |
R15487 | T19264 | T19267 | punct | ",",genes |
R15488 | T19265 | T19267 | amod | NF-κB,genes |
R15489 | T19266 | T19267 | compound | target,genes |
R15490 | T19267 | T19255 | conj | genes,attenuates |
R15491 | T19268 | T19267 | punct | ",",genes |
R15492 | T19269 | T19272 | prep | in,genes |
R15493 | T19270 | T19269 | amod | particular,in |
R15494 | T19271 | T19272 | det | those,genes |
R15495 | T19272 | T19267 | conj | genes,genes |
R15496 | T19273 | T19272 | acl | associated,genes |
R15497 | T19274 | T19273 | prep | with,associated |
R15498 | T19275 | T19277 | amod | acute,responses |
R15499 | T19276 | T19277 | amod | proinflammatory,responses |
R15500 | T19277 | T19274 | pobj | responses,with |
R15501 | T19278 | T19277 | punct | ",",responses |
R15502 | T19279 | T19277 | prep | including,responses |
R15503 | T19280 | T19279 | pobj | IL8,including |
R15504 | T19281 | T19280 | cc | and,IL8 |
R15505 | T19282 | T19280 | conj | TNF,IL8 |
R15506 | T19283 | T19255 | punct | .,attenuates |
R15507 | T19284 | T19290 | prep | In,block |
R15508 | T19285 | T19284 | pobj | contrast,In |
R15509 | T19286 | T19290 | punct | ",",block |
R15510 | T19287 | T19290 | nsubj | NleH1,block |
R15511 | T19288 | T19290 | aux | does,block |
R15512 | T19289 | T19290 | neg | not,block |
R15513 | T19290 | T19290 | ROOT | block,block |
R15514 | T19291 | T19294 | nmod | NF-κB,translocation |
R15515 | T19292 | T19291 | nummod | p65,NF-κB |
R15516 | T19293 | T19294 | amod | nuclear,translocation |
R15517 | T19294 | T19290 | dobj | translocation,block |
R15518 | T19295 | T19294 | punct | ",",translocation |
R15519 | T19296 | T19297 | nsubj | which,suggests |
R15520 | T19297 | T19294 | relcl | suggests,translocation |
R15521 | T19298 | T19308 | mark | that,be |
R15522 | T19299 | T19305 | amod | certain,genes |
R15523 | T19300 | T19304 | nmod | p65-dependent,target |
R15524 | T19301 | T19300 | cc | but,p65-dependent |
R15525 | T19302 | T19300 | conj | RPS3-independent,p65-dependent |
R15526 | T19303 | T19304 | compound | NF-κB,target |
R15527 | T19304 | T19305 | compound | target,genes |
R15528 | T19305 | T19308 | nsubj | genes,be |
R15529 | T19306 | T19308 | aux | might,be |
R15530 | T19307 | T19308 | advmod | thus,be |
R15531 | T19308 | T19297 | ccomp | be,suggests |
R15532 | T19309 | T19308 | acomp | beneficial,be |
R15533 | T19310 | T19309 | prep | for,beneficial |
R15534 | T19311 | T19313 | compound | E.,O157 |
R15535 | T19312 | T19313 | compound | coli,O157 |
R15536 | T19313 | T19310 | pobj | O157,for |
R15537 | T19314 | T19294 | punct | :,translocation |
R15538 | T19315 | T19294 | appos | H7,translocation |
R15539 | T19316 | T19317 | aux | to,replicate |
R15540 | T19317 | T19290 | advcl | replicate,block |
R15541 | T19318 | T19317 | cc | and,replicate |
R15542 | T19319 | T19317 | conj | disseminate,replicate |
R15543 | T19320 | T19319 | prep | in,disseminate |
R15544 | T19321 | T19322 | det | the,host |
R15545 | T19322 | T19320 | pobj | host,in |
R15546 | T19323 | T19290 | punct | .,block |
R15547 | T19324 | T19338 | prep | By,achieves |
R15548 | T19325 | T19326 | advmod | selectively,inhibiting |
R15549 | T19326 | T19324 | pcomp | inhibiting,By |
R15550 | T19327 | T19326 | dobj | RPS3,inhibiting |
R15551 | T19328 | T19327 | cc | and,RPS3 |
R15552 | T19329 | T19332 | poss | its,function |
R15553 | T19330 | T19332 | amod | attendant,function |
R15554 | T19331 | T19332 | compound | NF-κB,function |
R15555 | T19332 | T19327 | conj | function,RPS3 |
R15556 | T19333 | T19326 | prep | with,inhibiting |
R15557 | T19334 | T19333 | pobj | NleH1,with |
R15558 | T19335 | T19338 | punct | ",",achieves |
R15559 | T19336 | T19337 | det | the,pathogen |
R15560 | T19337 | T19338 | nsubj | pathogen,achieves |
R15561 | T19338 | T19338 | ROOT | achieves,achieves |
R15562 | T19339 | T19340 | det | the,ability |
R15563 | T19340 | T19338 | dobj | ability,achieves |
R15564 | T19341 | T19342 | aux | to,increase |
R15565 | T19342 | T19340 | acl | increase,ability |
R15566 | T19343 | T19342 | dobj | colonization,increase |
R15567 | T19344 | T19343 | cc | and,colonization |
R15568 | T19345 | T19343 | conj | diarrhea,colonization |
R15569 | T19346 | T19347 | advmod | yet,limiting |
R15570 | T19347 | T19338 | advcl | limiting,achieves |
R15571 | T19348 | T19349 | det | the,mortality |
R15572 | T19349 | T19347 | dobj | mortality,limiting |
R15573 | T19350 | T19349 | prep | of,mortality |
R15574 | T19351 | T19352 | det | the,host |
R15575 | T19352 | T19350 | pobj | host,of |
R15576 | T19353 | T19338 | punct | .,achieves |
R15577 | T19354 | T19357 | det | This,combination |
R15578 | T19355 | T19356 | advmod | seemingly,paradoxical |
R15579 | T19356 | T19357 | amod | paradoxical,combination |
R15580 | T19357 | T19360 | nsubj | combination,make |
R15581 | T19358 | T19357 | prep | of,combination |
R15582 | T19359 | T19358 | pobj | effects,of |
R15583 | T19360 | T19360 | ROOT | make,make |
R15584 | T19361 | T19360 | dobj | sense,make |
R15585 | T19362 | T19364 | advmod | when,considers |
R15586 | T19363 | T19364 | nsubj | one,considers |
R15587 | T19364 | T19360 | advcl | considers,make |
R15588 | T19365 | T19379 | mark | that,promote |
R15589 | T19366 | T19368 | amod | increased,load |
R15590 | T19367 | T19368 | amod | bacterial,load |
R15591 | T19368 | T19379 | nsubj | load,promote |
R15592 | T19369 | T19368 | cc | and,load |
R15593 | T19370 | T19368 | conj | diarrhea,load |
R15594 | T19371 | T19372 | advmod | together,with |
R15595 | T19372 | T19368 | prep | with,load |
R15596 | T19373 | T19372 | pobj | survival,with |
R15597 | T19374 | T19373 | prep | of,survival |
R15598 | T19375 | T19377 | det | the,host |
R15599 | T19376 | T19377 | amod | infected,host |
R15600 | T19377 | T19374 | pobj | host,of |
R15601 | T19378 | T19379 | aux | would,promote |
R15602 | T19379 | T19364 | ccomp | promote,considers |
R15603 | T19380 | T19381 | det | the,spreading |
R15604 | T19381 | T19379 | dobj | spreading,promote |
R15605 | T19382 | T19381 | prep | of,spreading |
R15606 | T19383 | T19384 | det | the,bacteria |
R15607 | T19384 | T19382 | pobj | bacteria,of |
R15608 | T19385 | T19381 | prep | among,spreading |
R15609 | T19386 | T19387 | det | a,population |
R15610 | T19387 | T19385 | pobj | population,among |
R15611 | T19388 | T19387 | prep | of,population |
R15612 | T19389 | T19390 | amod | susceptible,individuals |
R15613 | T19390 | T19388 | pobj | individuals,of |
R15614 | T19391 | T19360 | punct | .,make |
R15615 | T19392 | T19393 | amod | Such,complex |
R15616 | T19393 | T19404 | nsubj | complex,are |
R15617 | T19394 | T19393 | cc | and,complex |
R15618 | T19395 | T19397 | amod | paradoxical,effects |
R15619 | T19396 | T19397 | amod | pathological,effects |
R15620 | T19397 | T19393 | conj | effects,complex |
R15649 | T19426 | T19425 | dobj | RPS3,impeding |
R15650 | T19427 | T19417 | punct | ",",alterations |
R15651 | T19428 | T19417 | cc | but,alterations |
R15652 | T19429 | T19430 | neg | not,altering |
R15653 | T19430 | T19436 | advcl | altering,influence |
R15654 | T19431 | T19433 | nummod | p65,translocation |
R15655 | T19432 | T19433 | amod | nuclear,translocation |
R15656 | T19433 | T19430 | dobj | translocation,altering |
R15657 | T19434 | T19436 | punct | ",",influence |
R15658 | T19435 | T19436 | aux | can,influence |
R15659 | T19436 | T19415 | ccomp | influence,elucidate |
R15660 | T19437 | T19438 | amod | specific,cytokines |
R15661 | T19438 | T19436 | dobj | cytokines,influence |
R15662 | T19439 | T19440 | nsubj | that,affect |
R15663 | T19440 | T19438 | relcl | affect,cytokines |
R15664 | T19441 | T19442 | amod | bacterial,colonization |
R15665 | T19442 | T19440 | dobj | colonization,affect |
R15666 | T19443 | T19442 | punct | ",",colonization |
R15667 | T19444 | T19445 | compound | diarrhea,diseases |
R15668 | T19445 | T19442 | conj | diseases,colonization |
R15669 | T19446 | T19445 | cc | and,diseases |
R15670 | T19447 | T19445 | conj | mortality,diseases |
R15671 | T19448 | T19415 | punct | .,elucidate |
R15672 | T19449 | T19451 | nsubj | It,be |
R15673 | T19450 | T19451 | aux | may,be |
R15674 | T19451 | T19451 | ROOT | be,be |
R15675 | T19452 | T19451 | acomp | fruitful,be |
R15676 | T19453 | T19451 | prep | in,be |
R15677 | T19454 | T19453 | pcomp | attempting,in |
R15678 | T19455 | T19456 | aux | to,understand |
R15679 | T19456 | T19454 | xcomp | understand,attempting |
R15680 | T19457 | T19461 | amod | other,diseases |
R15681 | T19458 | T19461 | amod | infectious,diseases |
R15682 | T19459 | T19458 | cc | and,infectious |
R15683 | T19460 | T19458 | conj | autoimmune,infectious |
R15684 | T19461 | T19456 | dobj | diseases,understand |
R15685 | T19462 | T19461 | acl | involving,diseases |
R15686 | T19463 | T19462 | dobj | NF-κB,involving |
R15687 | T19464 | T19465 | aux | to,consider |
R15688 | T19465 | T19456 | advcl | consider,understand |
R15689 | T19466 | T19467 | amod | selective,effects |
R15690 | T19467 | T19465 | dobj | effects,consider |
R15691 | T19468 | T19467 | prep | of,effects |
R15692 | T19469 | T19468 | pobj | subunits,of |
R15693 | T19470 | T19471 | amod | such,as |
R15694 | T19471 | T19469 | prep | as,subunits |
R15695 | T19472 | T19471 | pobj | RPS3,as |
R15696 | T19473 | T19465 | prep | in,consider |
R15697 | T19474 | T19473 | pobj | addition,in |
R15698 | T19475 | T19474 | prep | to,addition |
R15699 | T19476 | T19478 | amod | global,inhibition |
R15700 | T19477 | T19478 | compound | NF-κB,inhibition |
R15701 | T19478 | T19475 | pobj | inhibition,to |
R15702 | T19479 | T19451 | punct | .,be |
R15621 | T19398 | T19399 | nsubj | that,influence |
R15622 | T19399 | T19397 | relcl | influence,effects |
R15623 | T19400 | T19401 | det | the,spread |
R15624 | T19401 | T19399 | dobj | spread,influence |
R15625 | T19402 | T19401 | prep | of,spread |
R15626 | T19403 | T19402 | pobj | disease,of |
R15627 | T19404 | T19407 | auxpass | are,understood |
R15628 | T19405 | T19407 | advmod | often,understood |
R15629 | T19406 | T19407 | advmod | poorly,understood |
R15630 | T19407 | T19407 | ROOT | understood,understood |
R15631 | T19408 | T19407 | prep | at,understood |
R15632 | T19409 | T19411 | det | the,level |
R15633 | T19410 | T19411 | amod | molecular,level |
R15634 | T19411 | T19408 | pobj | level,at |
R15635 | T19412 | T19407 | punct | .,understood |
R15636 | T19413 | T19414 | poss | Our,data |
R15637 | T19414 | T19415 | nsubj | data,elucidate |
R15638 | T19415 | T19415 | ROOT | elucidate,elucidate |
R15639 | T19416 | T19436 | advmod | how,influence |
R15640 | T19417 | T19436 | dep | alterations,influence |
R15641 | T19418 | T19417 | prep | in,alterations |
R15642 | T19419 | T19421 | amod | selective,function |
R15643 | T19420 | T19421 | compound | NF-κB,function |
R15644 | T19421 | T19418 | pobj | function,in |
R15645 | T19422 | T19421 | punct | ",",function |
R15646 | T19423 | T19421 | acl | achieved,function |
R15647 | T19424 | T19423 | prep | by,achieved |
R15648 | T19425 | T19424 | pcomp | impeding,by |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T19593 | 153-169 | http://purl.obolibrary.org/obo/GO_0051092 | denotes | NF-κB activation |
T19594 | 1578-1594 | http://purl.obolibrary.org/obo/GO_0051092 | denotes | NF-κB activation |
T19595 | 153-179 | http://purl.obolibrary.org/obo/GO_1901224 | denotes | NF-κB activation signaling |
T19596 | 1578-1604 | http://purl.obolibrary.org/obo/GO_1901224 | denotes | NF-κB activation signaling |
T19597 | 170-179 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
T19598 | 1595-1604 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
T19599 | 1803-1812 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
T19600 | 2153-2162 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
T19601 | 2520-2529 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
T19602 | 2593-2602 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
T19603 | 303-318 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
T19604 | 746-761 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
T19605 | 876-891 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
T19606 | 1201-1216 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
T19607 | 1465-1480 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
T19608 | 1717-1732 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
T19609 | 2035-2050 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
T19610 | 2284-2299 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
T19611 | 370-384 | http://purl.obolibrary.org/obo/GO_0051170 | denotes | nuclear import |
T19612 | 625-628 | http://purl.obolibrary.org/obo/GO_0008384 | denotes | IKK |
T19613 | 1368-1371 | http://purl.obolibrary.org/obo/GO_0008384 | denotes | IKK |
T19614 | 1427-1430 | http://purl.obolibrary.org/obo/GO_0008384 | denotes | IKK |
T19615 | 998-1011 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
T19616 | 2766-2779 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
T19617 | 1641-1653 | http://purl.obolibrary.org/obo/GO_0009405 | denotes | pathogenesis |
T19618 | 1797-1812 | http://purl.obolibrary.org/obo/GO_0038061 | denotes | NF-κB signaling |
T19619 | 2147-2162 | http://purl.obolibrary.org/obo/GO_0038061 | denotes | NF-κB signaling |
T19620 | 2514-2529 | http://purl.obolibrary.org/obo/GO_0038061 | denotes | NF-κB signaling |
T19621 | 2587-2602 | http://purl.obolibrary.org/obo/GO_0038061 | denotes | NF-κB signaling |
T19622 | 2220-2235 | http://purl.obolibrary.org/obo/GO_0016301 | denotes | kinase activity |
T19623 | 2751-2779 | http://purl.obolibrary.org/obo/GO_0031555 | denotes | attenuates the transcription |
GO-MF
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T19624 | 625-628 | http://purl.obolibrary.org/obo/GO_0008384 | denotes | IKK |
T19625 | 1368-1371 | http://purl.obolibrary.org/obo/GO_0008384 | denotes | IKK |
T19626 | 1427-1430 | http://purl.obolibrary.org/obo/GO_0008384 | denotes | IKK |
T19627 | 2220-2235 | http://purl.obolibrary.org/obo/GO_0016301 | denotes | kinase activity |
GO-CC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T19639 | 1894-1899 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T19640 | 2390-2395 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T19628 | 250-257 | http://purl.obolibrary.org/obo/GO_0005634 | denotes | nucleus |
T19629 | 1792-1796 | http://purl.obolibrary.org/obo/GO_0018995 | denotes | host |
T19630 | 1889-1893 | http://purl.obolibrary.org/obo/GO_0018995 | denotes | host |
T19631 | 2385-2389 | http://purl.obolibrary.org/obo/GO_0018995 | denotes | host |
T19632 | 2509-2513 | http://purl.obolibrary.org/obo/GO_0018995 | denotes | host |
T19633 | 2582-2586 | http://purl.obolibrary.org/obo/GO_0018995 | denotes | host |
T19634 | 3160-3164 | http://purl.obolibrary.org/obo/GO_0018995 | denotes | host |
T19635 | 3348-3352 | http://purl.obolibrary.org/obo/GO_0018995 | denotes | host |
T19636 | 3516-3520 | http://purl.obolibrary.org/obo/GO_0018995 | denotes | host |
T19637 | 1889-1899 | http://purl.obolibrary.org/obo/GO_0043657 | denotes | host cells |
T19638 | 2385-2395 | http://purl.obolibrary.org/obo/GO_0043657 | denotes | host cells |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T18122 | 11-120 | Sentence | denotes | RPS3 was previously demonstrated to function as an integral subunit conferring NF-κB regulatory specificity6. |
T18123 | 121-258 | Sentence | denotes | Here we sought to elucidate how NF-κB activation signaling triggers RPS3 to translocate and participate in NF-κB function in the nucleus. |
T18124 | 259-454 | Sentence | denotes | We demonstrate that IKKβ-mediated RPS3 S209 phosphorylation represents a critical determinant in governing its nuclear import thus unveiling a novel mechanism behind NF-κB regulatory specificity. |
T18125 | 455-579 | Sentence | denotes | IKKβ is the major kinase that phosphorylates IκBs in the classical NF-κB pathway, leading to their subsequent degradation40. |
T18126 | 580-687 | Sentence | denotes | Strikingly, RPS3 possesses not any consensus IKK motif; instead, S209 is centered in a consensus CK2 motif. |
T18127 | 688-861 | Sentence | denotes | The recent observation that human IKKβ displayed CK2-like phosphorylation specificity29 coincides with our evidence that recombinant IKKβ, but not IKKα, phosphorylated RPS3. |
T18128 | 862-1012 | Sentence | denotes | We found this phosphorylation is a critical modulation for RPS3 nuclear translocation (via importin-α) and engagement in specific NF-κB transcription. |
T18129 | 1013-1305 | Sentence | denotes | CK2 was previously shown to phosphorylate p65 and to bind to and phosphorylate IKKβ41-43, however, we ruled out the possibility that the IKKβ-bound CK2 could account for the observed RPS3 phosphorylation because no CK2 was detected in the IKKβ preparations used for the in vitro kinase assay. |
T18130 | 1306-1492 | Sentence | denotes | Because RPS3 only harbors the CK2 motif and not a traditional IKK motif, this RPS3 regulatory function could explain why IKK harbors the alternative substrate phosphorylation capability. |
T18131 | 1493-1692 | Sentence | denotes | More importantly, our study has elucidated how RPS3 is biochemically integrated into NF-κB activation signaling in a manner that is pivotal for the pathogenesis of foodborne pathogen E. coli O157:H7. |
T18132 | 1693-1813 | Sentence | denotes | IKKβ-mediated RPS3 S209 phosphorylation is a critical target modulated by this pathogen to subvert host NF-κB signaling. |
T18133 | 1814-1979 | Sentence | denotes | The bacterial effector NleH1 specifically binds to RPS3 once injected into host cells and profoundly suppresses NF-κB and its attendant protective immune responses9. |
T18134 | 1980-2163 | Sentence | denotes | Our data now show that NleH1 selectively inhibits RPS3 phosphorylation, thus retarding its nuclear translocation and subsequent NF-κB function, without altering other NF-κB signaling. |
T18135 | 2164-2300 | Sentence | denotes | Although NleH1 did not directly phosphorylate IKKβ, its kinase activity was required to inhibit IKKβ-mediated RPS3 S209 phosphorylation. |
T18136 | 2301-2530 | Sentence | denotes | Many bacteria pathogens have products that target key kinases to inactivate them in host cells, whereas E. coli O157:H7 employed NleH1 to steer the substrate specificity of IKKβ thus specifically fine-tuning host NF-κB signaling. |
T18137 | 2531-2643 | Sentence | denotes | This could represent a novel strategy to fine-tune host NF-κB signaling that could be shared by other pathogens. |
T18138 | 2644-2744 | Sentence | denotes | These data provide new insights into the poorly understood action mechanism for most T3SS effectors. |
T18139 | 2745-2929 | Sentence | denotes | NleH1 attenuates the transcription of RPS3-dependent, but not all, NF-κB target genes, in particular those genes associated with acute proinflammatory responses, including IL8 and TNF. |
T18140 | 2930-3165 | Sentence | denotes | In contrast, NleH1 does not block NF-κB p65 nuclear translocation, which suggests that certain p65-dependent but RPS3-independent NF-κB target genes might thus be beneficial for E. coli O157:H7 to replicate and disseminate in the host. |
T18141 | 3166-3353 | Sentence | denotes | By selectively inhibiting RPS3 and its attendant NF-κB function with NleH1, the pathogen achieves the ability to increase colonization and diarrhea yet limiting the mortality of the host. |
T18142 | 3354-3611 | Sentence | denotes | This seemingly paradoxical combination of effects make sense when one considers that increased bacterial load and diarrhea together with survival of the infected host would promote the spreading of the bacteria among a population of susceptible individuals. |
T18143 | 3612-3750 | Sentence | denotes | Such complex and paradoxical pathological effects that influence the spread of disease are often poorly understood at the molecular level. |
T18144 | 3751-3987 | Sentence | denotes | Our data elucidate how alterations in selective NF-κB function, achieved by impeding RPS3, but not altering p65 nuclear translocation, can influence specific cytokines that affect bacterial colonization, diarrhea diseases and mortality. |
T18145 | 3988-4186 | Sentence | denotes | It may be fruitful in attempting to understand other infectious and autoimmune diseases involving NF-κB to consider selective effects of subunits such as RPS3 in addition to global NF-κB inhibition. |
T164 | 0-10 | Sentence | denotes | Discussion |
T165 | 11-120 | Sentence | denotes | RPS3 was previously demonstrated to function as an integral subunit conferring NF-κB regulatory specificity6. |
T166 | 121-258 | Sentence | denotes | Here we sought to elucidate how NF-κB activation signaling triggers RPS3 to translocate and participate in NF-κB function in the nucleus. |
T167 | 259-454 | Sentence | denotes | We demonstrate that IKKβ-mediated RPS3 S209 phosphorylation represents a critical determinant in governing its nuclear import thus unveiling a novel mechanism behind NF-κB regulatory specificity. |
T168 | 455-579 | Sentence | denotes | IKKβ is the major kinase that phosphorylates IκBs in the classical NF-κB pathway, leading to their subsequent degradation40. |
T169 | 580-687 | Sentence | denotes | Strikingly, RPS3 possesses not any consensus IKK motif; instead, S209 is centered in a consensus CK2 motif. |
T170 | 688-861 | Sentence | denotes | The recent observation that human IKKβ displayed CK2-like phosphorylation specificity29 coincides with our evidence that recombinant IKKβ, but not IKKα, phosphorylated RPS3. |
T171 | 862-1012 | Sentence | denotes | We found this phosphorylation is a critical modulation for RPS3 nuclear translocation (via importin-α) and engagement in specific NF-κB transcription. |
T172 | 1013-1305 | Sentence | denotes | CK2 was previously shown to phosphorylate p65 and to bind to and phosphorylate IKKβ41-43, however, we ruled out the possibility that the IKKβ-bound CK2 could account for the observed RPS3 phosphorylation because no CK2 was detected in the IKKβ preparations used for the in vitro kinase assay. |
T173 | 1306-1492 | Sentence | denotes | Because RPS3 only harbors the CK2 motif and not a traditional IKK motif, this RPS3 regulatory function could explain why IKK harbors the alternative substrate phosphorylation capability. |
T174 | 1493-1692 | Sentence | denotes | More importantly, our study has elucidated how RPS3 is biochemically integrated into NF-κB activation signaling in a manner that is pivotal for the pathogenesis of foodborne pathogen E. coli O157:H7. |
T175 | 1693-1813 | Sentence | denotes | IKKβ-mediated RPS3 S209 phosphorylation is a critical target modulated by this pathogen to subvert host NF-κB signaling. |
T176 | 1814-1979 | Sentence | denotes | The bacterial effector NleH1 specifically binds to RPS3 once injected into host cells and profoundly suppresses NF-κB and its attendant protective immune responses9. |
T177 | 1980-2163 | Sentence | denotes | Our data now show that NleH1 selectively inhibits RPS3 phosphorylation, thus retarding its nuclear translocation and subsequent NF-κB function, without altering other NF-κB signaling. |
T178 | 2164-2300 | Sentence | denotes | Although NleH1 did not directly phosphorylate IKKβ, its kinase activity was required to inhibit IKKβ-mediated RPS3 S209 phosphorylation. |
T179 | 2301-2530 | Sentence | denotes | Many bacteria pathogens have products that target key kinases to inactivate them in host cells, whereas E. coli O157:H7 employed NleH1 to steer the substrate specificity of IKKβ thus specifically fine-tuning host NF-κB signaling. |
T180 | 2531-2643 | Sentence | denotes | This could represent a novel strategy to fine-tune host NF-κB signaling that could be shared by other pathogens. |
T181 | 2644-2744 | Sentence | denotes | These data provide new insights into the poorly understood action mechanism for most T3SS effectors. |
T182 | 2745-2929 | Sentence | denotes | NleH1 attenuates the transcription of RPS3-dependent, but not all, NF-κB target genes, in particular those genes associated with acute proinflammatory responses, including IL8 and TNF. |
T183 | 2930-3165 | Sentence | denotes | In contrast, NleH1 does not block NF-κB p65 nuclear translocation, which suggests that certain p65-dependent but RPS3-independent NF-κB target genes might thus be beneficial for E. coli O157:H7 to replicate and disseminate in the host. |
T184 | 3166-3353 | Sentence | denotes | By selectively inhibiting RPS3 and its attendant NF-κB function with NleH1, the pathogen achieves the ability to increase colonization and diarrhea yet limiting the mortality of the host. |
T185 | 3354-3611 | Sentence | denotes | This seemingly paradoxical combination of effects make sense when one considers that increased bacterial load and diarrhea together with survival of the infected host would promote the spreading of the bacteria among a population of susceptible individuals. |
T186 | 3612-3750 | Sentence | denotes | Such complex and paradoxical pathological effects that influence the spread of disease are often poorly understood at the molecular level. |
T187 | 3751-3987 | Sentence | denotes | Our data elucidate how alterations in selective NF-κB function, achieved by impeding RPS3, but not altering p65 nuclear translocation, can influence specific cytokines that affect bacterial colonization, diarrhea diseases and mortality. |
T188 | 3988-4186 | Sentence | denotes | It may be fruitful in attempting to understand other infectious and autoimmune diseases involving NF-κB to consider selective effects of subunits such as RPS3 in addition to global NF-κB inhibition. |
events-check-again
Id | Subject | Object | Predicate | Lexical cue | Negation | Speculation |
---|---|---|---|---|---|---|
T20021 | 11-15 | Protein | denotes | RPS3 | ||
T20022 | 180-188 | Positive_regulation | denotes | triggers | true | |
T20023 | 189-193 | Protein | denotes | RPS3 | ||
T20024 | 197-208 | Localization | denotes | translocate | ||
T20025 | 250-257 | Entity | denotes | nucleus | ||
T20026 | 279-283 | Protein | denotes | IKKβ | ||
T20027 | 284-292 | Positive_regulation | denotes | mediated | ||
T20028 | 293-297 | Protein | denotes | RPS3 | ||
T20029 | 298-302 | Entity | denotes | S209 | ||
T20030 | 303-318 | Phosphorylation | denotes | phosphorylation | ||
T20031 | 332-340 | Regulation | denotes | critical | ||
T20032 | 370-377 | Entity | denotes | nuclear | ||
T20033 | 378-384 | Localization | denotes | import | ||
T20034 | 455-459 | Protein | denotes | IKKβ | ||
T20035 | 592-596 | Protein | denotes | RPS3 | ||
T20036 | 722-726 | Protein | denotes | IKKβ | ||
T20037 | 821-825 | Protein | denotes | IKKβ | ||
T20038 | 835-839 | Protein | denotes | IKKα | ||
T20039 | 841-855 | Phosphorylation | denotes | phosphorylated | ||
T20040 | 841-855 | Phosphorylation | denotes | phosphorylated | true | |
T20041 | 856-860 | Protein | denotes | RPS3 | ||
T20042 | 906-916 | Regulation | denotes | modulation | ||
T20043 | 906-916 | Regulation | denotes | modulation | ||
T20044 | 921-925 | Protein | denotes | RPS3 | ||
T20045 | 926-933 | Entity | denotes | nuclear | ||
T20046 | 934-947 | Localization | denotes | translocation | ||
T20047 | 949-952 | Positive_regulation | denotes | via | ||
T20048 | 1041-1054 | Phosphorylation | denotes | phosphorylate | ||
T20049 | 1055-1058 | Protein | denotes | p65 | ||
T20050 | 1066-1070 | Binding | denotes | bind | ||
T20051 | 1078-1091 | Phosphorylation | denotes | phosphorylate | ||
T20052 | 1092-1096 | Protein | denotes | IKKβ | ||
T20053 | 1150-1154 | Protein | denotes | IKKβ | ||
T20054 | 1155-1160 | Binding | denotes | bound | ||
T20055 | 1171-1182 | Positive_regulation | denotes | account for | true | |
T20056 | 1196-1200 | Protein | denotes | RPS3 | ||
T20057 | 1201-1216 | Phosphorylation | denotes | phosphorylation | ||
T20058 | 1252-1256 | Protein | denotes | IKKβ | ||
T20059 | 1314-1318 | Protein | denotes | RPS3 | ||
T20060 | 1540-1544 | Protein | denotes | RPS3 | ||
T20061 | 1693-1697 | Protein | denotes | IKKβ | ||
T20062 | 1698-1706 | Positive_regulation | denotes | mediated | ||
T20063 | 1707-1711 | Protein | denotes | RPS3 | ||
T20064 | 1712-1716 | Entity | denotes | S209 | ||
T20065 | 1717-1732 | Phosphorylation | denotes | phosphorylation | ||
T20066 | 1754-1763 | Regulation | denotes | modulated | ||
T20067 | 1837-1842 | Protein | denotes | NleH1 | ||
T20068 | 1856-1861 | Binding | denotes | binds | ||
T20069 | 1865-1869 | Protein | denotes | RPS3 | ||
T20070 | 2003-2008 | Protein | denotes | NleH1 | ||
T20071 | 2021-2029 | Negative_regulation | denotes | inhibits | ||
T20072 | 2030-2034 | Protein | denotes | RPS3 | ||
T20073 | 2035-2050 | Phosphorylation | denotes | phosphorylation | ||
T20074 | 2057-2066 | Negative_regulation | denotes | retarding | ||
T20075 | 2071-2078 | Entity | denotes | nuclear | ||
T20076 | 2079-2092 | Localization | denotes | translocation | ||
T20077 | 2173-2178 | Protein | denotes | NleH1 | ||
T20078 | 2196-2209 | Phosphorylation | denotes | phosphorylate | true | |
T20079 | 2210-2214 | Protein | denotes | IKKβ | ||
T20080 | 2252-2259 | Negative_regulation | denotes | inhibit | ||
T20081 | 2260-2264 | Protein | denotes | IKKβ | ||
T20082 | 2265-2273 | Positive_regulation | denotes | mediated | ||
T20083 | 2274-2278 | Protein | denotes | RPS3 | ||
T20084 | 2279-2283 | Entity | denotes | S209 | ||
T20085 | 2284-2299 | Phosphorylation | denotes | phosphorylation | ||
T20086 | 2430-2435 | Protein | denotes | NleH1 | ||
T20087 | 2439-2444 | Regulation | denotes | steer | ||
T20088 | 2474-2478 | Protein | denotes | IKKβ | ||
T20089 | 2745-2750 | Protein | denotes | NleH1 | ||
T20090 | 2783-2787 | Protein | denotes | RPS3 | ||
T20091 | 2917-2920 | Protein | denotes | IL8 | ||
T20092 | 2943-2948 | Protein | denotes | NleH1 | ||
T20093 | 2958-2963 | Negative_regulation | denotes | block | true | |
T20094 | 2970-2973 | Protein | denotes | p65 | ||
T20095 | 2974-2981 | Entity | denotes | nuclear | ||
T20096 | 2982-2995 | Localization | denotes | translocation | ||
T20097 | 3025-3028 | Protein | denotes | p65 | ||
T20098 | 3043-3047 | Protein | denotes | RPS3 | ||
T20099 | 3181-3191 | Negative_regulation | denotes | inhibiting | ||
T20100 | 3192-3196 | Protein | denotes | RPS3 | ||
T20101 | 3235-3240 | Protein | denotes | NleH1 | ||
T20102 | 3827-3835 | Negative_regulation | denotes | impeding | ||
T20103 | 3836-3840 | Protein | denotes | RPS3 | ||
T20104 | 3850-3858 | Regulation | denotes | altering | ||
T20105 | 3859-3862 | Protein | denotes | p65 | ||
T20106 | 3863-3870 | Entity | denotes | nuclear | ||
T20107 | 3871-3884 | Localization | denotes | translocation | ||
T20108 | 4114-4121 | Regulation | denotes | effects | ||
T20109 | 4142-4146 | Protein | denotes | RPS3 | ||
R15990 | T20023 | T20024 | themeOf | RPS3,translocate | ||
R15991 | T20024 | T20022 | themeOf | translocate,triggers | ||
R15992 | T20025 | T20024 | locationOf | nucleus,translocate | ||
R15993 | T20026 | T20027 | causeOf | IKKβ,mediated | ||
R15994 | T20027 | T20031 | causeOf | mediated,critical | ||
R15995 | T20028 | T20033 | themeOf | RPS3,import | ||
R15996 | T20029 | T20030 | themeOf | S209,phosphorylation | ||
R15997 | T20029 | T20028 | partOf | S209,RPS3 | ||
R15998 | T20030 | T20027 | themeOf | phosphorylation,mediated | ||
R15999 | T20032 | T20033 | locationOf | nuclear,import | ||
R16000 | T20033 | T20031 | themeOf | import,critical | ||
R16001 | T20037 | T20039 | causeOf | IKKβ,phosphorylated | ||
R16002 | T20038 | T20040 | causeOf | IKKα,phosphorylated | ||
R16003 | T20039 | T20043 | causeOf | phosphorylated,modulation | ||
R16004 | T20040 | T20042 | causeOf | phosphorylated,modulation | ||
R16005 | T20041 | T20039 | themeOf | RPS3,phosphorylated | ||
R16006 | T20041 | T20040 | themeOf | RPS3,phosphorylated | ||
R16007 | T20044 | T20046 | themeOf | RPS3,translocation | ||
R16008 | T20045 | T20046 | locationOf | nuclear,translocation | ||
R16009 | T20046 | T20043 | themeOf | translocation,modulation | ||
R16010 | T20046 | T20042 | themeOf | translocation,modulation | ||
R16011 | T20046 | T20047 | themeOf | translocation,via | ||
R16012 | T20049 | T20048 | themeOf | p65,phosphorylate | ||
R16013 | T20052 | T20050 | themeOf | IKKβ,bind | ||
R16014 | T20052 | T20051 | themeOf | IKKβ,phosphorylate | ||
R16015 | T20053 | T20054 | themeOf | IKKβ,bound | ||
R16016 | T20054 | T20055 | causeOf | bound,account for | ||
R16017 | T20056 | T20057 | themeOf | RPS3,phosphorylation | ||
R16018 | T20057 | T20055 | themeOf | phosphorylation,account for | ||
R16019 | T20061 | T20062 | causeOf | IKKβ,mediated | ||
R16020 | T20062 | T20066 | themeOf | mediated,modulated | ||
R16021 | T20064 | T20065 | themeOf | S209,phosphorylation | ||
R16022 | T20064 | T20063 | partOf | S209,RPS3 | ||
R16023 | T20065 | T20062 | themeOf | phosphorylation,mediated | ||
R16024 | T20067 | T20068 | themeOf | NleH1,binds | ||
R16025 | T20069 | T20068 | themeOf | RPS3,binds | ||
R16026 | T20070 | T20071 | causeOf | NleH1,inhibits | ||
R16027 | T20071 | T20074 | causeOf | inhibits,retarding | ||
R16028 | T20072 | T20073 | themeOf | RPS3,phosphorylation | ||
R16029 | T20072 | T20076 | themeOf | RPS3,translocation | ||
R16030 | T20073 | T20071 | themeOf | phosphorylation,inhibits | ||
R16031 | T20075 | T20076 | locationOf | nuclear,translocation | ||
R16032 | T20076 | T20074 | themeOf | translocation,retarding | ||
R16033 | T20079 | T20078 | themeOf | IKKβ,phosphorylate | ||
R16034 | T20081 | T20082 | causeOf | IKKβ,mediated | ||
R16035 | T20082 | T20080 | themeOf | mediated,inhibit | ||
R16036 | T20084 | T20085 | themeOf | S209,phosphorylation | ||
R16037 | T20084 | T20083 | partOf | S209,RPS3 | ||
R16038 | T20085 | T20082 | themeOf | phosphorylation,mediated | ||
R16039 | T20086 | T20087 | causeOf | NleH1,steer | ||
R16040 | T20088 | T20087 | themeOf | IKKβ,steer | ||
R16041 | T20092 | T20093 | causeOf | NleH1,block | ||
R16042 | T20094 | T20096 | themeOf | p65,translocation | ||
R16043 | T20095 | T20096 | locationOf | nuclear,translocation | ||
R16044 | T20096 | T20093 | themeOf | translocation,block | ||
R16045 | T20100 | T20099 | themeOf | RPS3,inhibiting | ||
R16046 | T20101 | T20099 | causeOf | NleH1,inhibiting | ||
R16047 | T20103 | T20102 | themeOf | RPS3,impeding | ||
R16048 | T20105 | T20107 | themeOf | p65,translocation | ||
R16049 | T20106 | T20107 | locationOf | nuclear,translocation | ||
R16050 | T20107 | T20104 | themeOf | translocation,altering | ||
R16051 | T20109 | T20108 | themeOf | RPS3,effects |
bionlp-st-ge-2016-reference-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T19641 | 11-15 | Protein | denotes | RPS3 |
T19642 | 90-119 | Protein | denotes | NF-κB regulatory specificity6 |
T19643 | 79-89 | Positive_regulation | denotes | conferring |
T19644 | 153-158 | Protein | denotes | NF-κB |
T19645 | 189-193 | Protein | denotes | RPS3 |
T19646 | 228-233 | Protein | denotes | NF-κB |
T19647 | 279-283 | Protein | denotes | IKKβ |
T19648 | 293-302 | Protein | denotes | RPS3 S209 |
T19649 | 425-430 | Protein | denotes | NF-κB |
T19650 | 303-318 | Phosphorylation | denotes | phosphorylation |
T19651 | 370-377 | Entity | denotes | nuclear |
T19652 | 284-292 | Positive_regulation | denotes | mediated |
T19653 | 455-459 | Protein | denotes | IKKβ |
T19654 | 500-504 | Protein | denotes | IκBs |
T19655 | 522-527 | Protein | denotes | NF-κB |
T19656 | 485-499 | Phosphorylation | denotes | phosphorylates |
T19657 | 485-499 | Phosphorylation | denotes | phosphorylates |
T19658 | 565-578 | Protein_catabolism | denotes | degradation40 |
T19659 | 565-578 | Protein_catabolism | denotes | degradation40 |
T19660 | 592-596 | Protein | denotes | RPS3 |
T19661 | 716-726 | Protein | denotes | human IKKβ |
T19662 | 737-740 | Protein | denotes | CK2 |
T19663 | 821-825 | Protein | denotes | IKKβ |
T19664 | 835-839 | Protein | denotes | IKKα |
T19665 | 856-860 | Protein | denotes | RPS3 |
T19666 | 746-761 | Phosphorylation | denotes | phosphorylation |
T19667 | 746-761 | Phosphorylation | denotes | phosphorylation |
T19668 | 841-855 | Phosphorylation | denotes | phosphorylated |
T19669 | 841-855 | Phosphorylation | denotes | phosphorylated |
T19670 | 841-855 | Phosphorylation | denotes | phosphorylated |
T19671 | 921-925 | Protein | denotes | RPS3 |
T19672 | 953-963 | Protein | denotes | importin-α |
T19673 | 992-997 | Protein | denotes | NF-κB |
T19674 | 926-933 | Entity | denotes | nuclear |
T19675 | 934-947 | Localization | denotes | translocation |
T19676 | 998-1011 | Transcription | denotes | transcription |
T19677 | 906-916 | Regulation | denotes | modulation |
T19678 | 1013-1016 | Protein | denotes | CK2 |
T19679 | 1055-1058 | Protein | denotes | p65 |
T19680 | 1150-1154 | Protein | denotes | IKKβ |
T19681 | 1161-1164 | Protein | denotes | CK2 |
T19682 | 1196-1200 | Protein | denotes | RPS3 |
T19683 | 1228-1231 | Protein | denotes | CK2 |
T19684 | 1252-1256 | Protein | denotes | IKKβ |
T19685 | 1041-1054 | Phosphorylation | denotes | phosphorylate |
T19686 | 1066-1070 | Binding | denotes | bind |
T19687 | 1155-1160 | Binding | denotes | bound |
T19688 | 1155-1160 | Binding | denotes | bound |
T19689 | 1201-1216 | Phosphorylation | denotes | phosphorylation |
T19690 | 1236-1244 | Gene_expression | denotes | detected |
T19691 | 1171-1178 | Positive_regulation | denotes | account |
T19692 | 1314-1318 | Protein | denotes | RPS3 |
T19693 | 1336-1345 | Protein | denotes | CK2 motif |
T19694 | 1384-1388 | Protein | denotes | RPS3 |
T19695 | 1427-1430 | Protein | denotes | IKK |
T19696 | 1465-1480 | Phosphorylation | denotes | phosphorylation |
T19697 | 1540-1544 | Protein | denotes | RPS3 |
T19698 | 1578-1583 | Protein | denotes | NF-κB |
T19699 | 1693-1697 | Protein | denotes | IKKβ |
T19700 | 1707-1716 | Protein | denotes | RPS3 S209 |
T19701 | 1797-1802 | Protein | denotes | NF-κB |
T19702 | 1717-1732 | Phosphorylation | denotes | phosphorylation |
T19703 | 1698-1706 | Positive_regulation | denotes | mediated |
T19704 | 1837-1842 | Protein | denotes | NleH1 |
T19705 | 1865-1869 | Protein | denotes | RPS3 |
T19706 | 1926-1931 | Protein | denotes | NF-κB |
T19707 | 1856-1861 | Binding | denotes | binds |
T19708 | 1915-1925 | Negative_regulation | denotes | suppresses |
T19709 | 2003-2008 | Protein | denotes | NleH1 |
T19710 | 2030-2034 | Protein | denotes | RPS3 |
T19711 | 2108-2113 | Protein | denotes | NF-κB |
T19712 | 2147-2152 | Protein | denotes | NF-κB |
T19713 | 2035-2050 | Phosphorylation | denotes | phosphorylation |
T19714 | 2079-2092 | Localization | denotes | translocation |
T19715 | 2079-2092 | Localization | denotes | translocation |
T19716 | 2021-2029 | Negative_regulation | denotes | inhibits |
T19717 | 2173-2186 | Protein | denotes | NleH1 did not |
T19718 | 2210-2214 | Protein | denotes | IKKβ |
T19719 | 2260-2264 | Protein | denotes | IKKβ |
T19720 | 2274-2278 | Protein | denotes | RPS3 |
T19721 | 2279-2283 | Protein | denotes | S209 |
T19722 | 2196-2209 | Phosphorylation | denotes | phosphorylate |
T19723 | 2196-2209 | Phosphorylation | denotes | phosphorylate |
T19724 | 2284-2299 | Phosphorylation | denotes | phosphorylation |
T19725 | 2284-2299 | Phosphorylation | denotes | phosphorylation |
T19726 | 2252-2259 | Negative_regulation | denotes | inhibit |
T19727 | 2252-2259 | Negative_regulation | denotes | inhibit |
T19728 | 2265-2273 | Positive_regulation | denotes | mediated |
T19729 | 2265-2273 | Positive_regulation | denotes | mediated |
T19730 | 2344-2362 | Protein | denotes | target key kinases |
T19731 | 2430-2435 | Protein | denotes | NleH1 |
T19732 | 2474-2478 | Protein | denotes | IKKβ |
T19733 | 2514-2519 | Protein | denotes | NF-κB |
T19734 | 2330-2338 | Gene_expression | denotes | products |
T19735 | 2587-2592 | Protein | denotes | NF-κB |
T19736 | 2745-2750 | Protein | denotes | NleH1 |
T19737 | 2783-2787 | Protein | denotes | RPS3 |
T19738 | 2812-2817 | Protein | denotes | NF-κB |
T19739 | 2917-2920 | Protein | denotes | IL8 |
T19740 | 2925-2928 | Protein | denotes | TNF |
T19741 | 2766-2779 | Transcription | denotes | transcription |
T19742 | 2766-2779 | Transcription | denotes | transcription |
T19743 | 2766-2779 | Transcription | denotes | transcription |
T19744 | 2943-2948 | Protein | denotes | NleH1 |
T19745 | 2964-2969 | Protein | denotes | NF-κB |
T19746 | 2970-2973 | Protein | denotes | p65 |
T19747 | 3043-3047 | Protein | denotes | RPS3 |
T19748 | 3060-3065 | Protein | denotes | NF-κB |
T19749 | 2974-2981 | Entity | denotes | nuclear |
T19750 | 2982-2995 | Localization | denotes | translocation |
T19751 | 2982-2995 | Localization | denotes | translocation |
T19752 | 2958-2963 | Negative_regulation | denotes | block |
T19753 | 2958-2963 | Negative_regulation | denotes | block |
T19754 | 3192-3196 | Protein | denotes | RPS3 |
T19755 | 3215-3220 | Protein | denotes | NF-κB |
T19756 | 3235-3240 | Protein | denotes | NleH1 |
T19757 | 3181-3191 | Negative_regulation | denotes | inhibiting |
T19758 | 3181-3191 | Negative_regulation | denotes | inhibiting |
T19759 | 3181-3191 | Negative_regulation | denotes | inhibiting |
T19760 | 3799-3804 | Protein | denotes | NF-κB |
T19761 | 3836-3840 | Protein | denotes | RPS3 |
T19762 | 3859-3862 | Protein | denotes | p65 |
T19763 | 3863-3870 | Entity | denotes | nuclear |
T19764 | 3871-3884 | Localization | denotes | translocation |
T19765 | 3850-3858 | Regulation | denotes | altering |
T19766 | 4086-4091 | Protein | denotes | NF-κB |
T19767 | 4142-4146 | Protein | denotes | RPS3 |
T19768 | 4169-4174 | Protein | denotes | NF-κB |
T19769 | 4175-4185 | Negative_regulation | denotes | inhibition |
R15765 | T19642 | T19643 | themeOf | NF-κB regulatory specificity6,conferring |
R15766 | T19647 | T19652 | causeOf | IKKβ,mediated |
R15767 | T19648 | T19650 | themeOf | RPS3 S209,phosphorylation |
R15768 | T19650 | T19652 | themeOf | phosphorylation,mediated |
R15769 | T19653 | T19656 | themeOf | IKKβ,phosphorylates |
R15770 | T19653 | T19658 | themeOf | IKKβ,degradation40 |
R15771 | T19654 | T19657 | themeOf | IκBs,phosphorylates |
R15772 | T19654 | T19659 | themeOf | IκBs,degradation40 |
R15773 | T19661 | T19666 | themeOf | human IKKβ,phosphorylation |
R15774 | T19662 | T19667 | themeOf | CK2,phosphorylation |
R15775 | T19663 | T19668 | themeOf | IKKβ,phosphorylated |
R15776 | T19664 | T19669 | themeOf | IKKα,phosphorylated |
R15777 | T19665 | T19670 | themeOf | RPS3,phosphorylated |
R15778 | T19671 | T19675 | themeOf | RPS3,translocation |
R15779 | T19673 | T19676 | themeOf | NF-κB,transcription |
R15780 | T19674 | T19675 | locationOf | nuclear,translocation |
R15781 | T19675 | T19677 | themeOf | translocation,modulation |
R15782 | T19678 | T19686 | themeOf | CK2,bind |
R15783 | T19679 | T19685 | themeOf | p65,phosphorylate |
R15784 | T19680 | T19687 | themeOf | IKKβ,bound |
R15785 | T19680 | T19688 | themeOf | IKKβ,bound |
R15786 | T19681 | T19688 | themeOf | CK2,bound |
R15787 | T19681 | T19691 | causeOf | CK2,account |
R15788 | T19682 | T19689 | themeOf | RPS3,phosphorylation |
R15789 | T19683 | T19690 | themeOf | CK2,detected |
R15790 | T19689 | T19691 | themeOf | phosphorylation,account |
R15791 | T19695 | T19696 | themeOf | IKK,phosphorylation |
R15792 | T19699 | T19703 | causeOf | IKKβ,mediated |
R15793 | T19700 | T19702 | themeOf | RPS3 S209,phosphorylation |
R15794 | T19702 | T19703 | themeOf | phosphorylation,mediated |
R15795 | T19704 | T19707 | themeOf | NleH1,binds |
R15796 | T19704 | T19708 | causeOf | NleH1,suppresses |
R15797 | T19705 | T19707 | themeOf | RPS3,binds |
R15798 | T19706 | T19708 | themeOf | NF-κB,suppresses |
R15799 | T19709 | T19716 | causeOf | NleH1,inhibits |
R15800 | T19710 | T19713 | themeOf | RPS3,phosphorylation |
R15801 | T19710 | T19714 | themeOf | RPS3,translocation |
R15802 | T19711 | T19715 | themeOf | NF-κB,translocation |
R15803 | T19713 | T19716 | themeOf | phosphorylation,inhibits |
R15804 | T19717 | T19722 | themeOf | NleH1 did not,phosphorylate |
R15805 | T19718 | T19723 | themeOf | IKKβ,phosphorylate |
R15806 | T19719 | T19728 | causeOf | IKKβ,mediated |
R15807 | T19719 | T19729 | causeOf | IKKβ,mediated |
R15808 | T19720 | T19724 | themeOf | RPS3,phosphorylation |
R15809 | T19721 | T19725 | themeOf | S209,phosphorylation |
R15810 | T19724 | T19726 | themeOf | phosphorylation,inhibit |
R15811 | T19724 | T19728 | themeOf | phosphorylation,mediated |
R15812 | T19725 | T19727 | themeOf | phosphorylation,inhibit |
R15813 | T19725 | T19729 | themeOf | phosphorylation,mediated |
R15814 | T19730 | T19734 | themeOf | target key kinases,products |
R15815 | T19736 | T19741 | themeOf | NleH1,transcription |
R15816 | T19737 | T19742 | themeOf | RPS3,transcription |
R15817 | T19738 | T19743 | themeOf | NF-κB,transcription |
R15818 | T19744 | T19752 | causeOf | NleH1,block |
R15819 | T19744 | T19753 | causeOf | NleH1,block |
R15820 | T19745 | T19750 | themeOf | NF-κB,translocation |
R15821 | T19746 | T19751 | themeOf | p65,translocation |
R15822 | T19749 | T19750 | locationOf | nuclear,translocation |
R15823 | T19749 | T19751 | locationOf | nuclear,translocation |
R15824 | T19750 | T19752 | themeOf | translocation,block |
R15825 | T19751 | T19753 | themeOf | translocation,block |
R15826 | T19754 | T19757 | themeOf | RPS3,inhibiting |
R15827 | T19755 | T19758 | themeOf | NF-κB,inhibiting |
R15828 | T19756 | T19759 | themeOf | NleH1,inhibiting |
R15829 | T19762 | T19764 | themeOf | p65,translocation |
R15830 | T19763 | T19764 | locationOf | nuclear,translocation |
R15831 | T19764 | T19765 | themeOf | translocation,altering |
R15832 | T19768 | T19769 | themeOf | NF-κB,inhibition |
bionlp-st-ge-2016-reference
Id | Subject | Object | Predicate | Lexical cue | Negation | Speculation |
---|---|---|---|---|---|---|
T18033 | 11-15 | Protein | denotes | RPS3 | ||
T18034 | 180-188 | Positive_regulation | denotes | triggers | true | |
T18035 | 189-193 | Protein | denotes | RPS3 | ||
T18036 | 197-208 | Localization | denotes | translocate | ||
T18037 | 250-257 | Entity | denotes | nucleus | ||
T18038 | 279-283 | Protein | denotes | IKKβ | ||
T18039 | 284-292 | Positive_regulation | denotes | mediated | ||
T18040 | 293-297 | Protein | denotes | RPS3 | ||
T18041 | 298-302 | Entity | denotes | S209 | ||
T18042 | 303-318 | Phosphorylation | denotes | phosphorylation | ||
T18043 | 332-340 | Regulation | denotes | critical | ||
T18044 | 370-377 | Entity | denotes | nuclear | ||
T18045 | 378-384 | Localization | denotes | import | ||
T18046 | 455-459 | Protein | denotes | IKKβ | ||
T18047 | 592-596 | Protein | denotes | RPS3 | ||
T18048 | 722-726 | Protein | denotes | IKKβ | ||
T18049 | 821-825 | Protein | denotes | IKKβ | ||
T18050 | 835-839 | Protein | denotes | IKKα | ||
T18051 | 841-855 | Phosphorylation | denotes | phosphorylated | ||
T18052 | 841-855 | Phosphorylation | denotes | phosphorylated | true | |
T18053 | 856-860 | Protein | denotes | RPS3 | ||
T18054 | 906-916 | Regulation | denotes | modulation | ||
T18055 | 906-916 | Regulation | denotes | modulation | ||
T18056 | 921-925 | Protein | denotes | RPS3 | ||
T18057 | 926-933 | Entity | denotes | nuclear | ||
T18058 | 934-947 | Localization | denotes | translocation | ||
T18059 | 949-952 | Positive_regulation | denotes | via | ||
T18060 | 1041-1054 | Phosphorylation | denotes | phosphorylate | ||
T18061 | 1055-1058 | Protein | denotes | p65 | ||
T18062 | 1066-1070 | Binding | denotes | bind | ||
T18063 | 1078-1091 | Phosphorylation | denotes | phosphorylate | ||
T18064 | 1092-1096 | Protein | denotes | IKKβ | ||
T18065 | 1150-1154 | Protein | denotes | IKKβ | ||
T18066 | 1155-1160 | Binding | denotes | bound | ||
T18067 | 1171-1182 | Positive_regulation | denotes | account for | true | |
T18068 | 1196-1200 | Protein | denotes | RPS3 | ||
T18069 | 1201-1216 | Phosphorylation | denotes | phosphorylation | ||
T18070 | 1252-1256 | Protein | denotes | IKKβ | ||
T18071 | 1314-1318 | Protein | denotes | RPS3 | ||
T18072 | 1540-1544 | Protein | denotes | RPS3 | ||
T18073 | 1693-1697 | Protein | denotes | IKKβ | ||
T18074 | 1698-1706 | Positive_regulation | denotes | mediated | ||
T18075 | 1707-1711 | Protein | denotes | RPS3 | ||
T18076 | 1712-1716 | Entity | denotes | S209 | ||
T18077 | 1717-1732 | Phosphorylation | denotes | phosphorylation | ||
T18078 | 1754-1763 | Regulation | denotes | modulated | ||
T18079 | 1837-1842 | Protein | denotes | NleH1 | ||
T18080 | 1856-1861 | Binding | denotes | binds | ||
T18081 | 1865-1869 | Protein | denotes | RPS3 | ||
T18082 | 2003-2008 | Protein | denotes | NleH1 | ||
T18083 | 2021-2029 | Negative_regulation | denotes | inhibits | ||
T18084 | 2030-2034 | Protein | denotes | RPS3 | ||
T18085 | 2035-2050 | Phosphorylation | denotes | phosphorylation | ||
T18086 | 2057-2066 | Negative_regulation | denotes | retarding | ||
T18087 | 2071-2078 | Entity | denotes | nuclear | ||
T18088 | 2079-2092 | Localization | denotes | translocation | ||
T18089 | 2173-2178 | Protein | denotes | NleH1 | ||
T18090 | 2196-2209 | Phosphorylation | denotes | phosphorylate | true | |
T18091 | 2210-2214 | Protein | denotes | IKKβ | ||
T18092 | 2252-2259 | Negative_regulation | denotes | inhibit | ||
T18093 | 2260-2264 | Protein | denotes | IKKβ | ||
T18094 | 2265-2273 | Positive_regulation | denotes | mediated | ||
T18095 | 2274-2278 | Protein | denotes | RPS3 | ||
T18096 | 2279-2283 | Entity | denotes | S209 | ||
T18097 | 2284-2299 | Phosphorylation | denotes | phosphorylation | ||
T18098 | 2430-2435 | Protein | denotes | NleH1 | ||
T18099 | 2439-2444 | Regulation | denotes | steer | ||
T18100 | 2474-2478 | Protein | denotes | IKKβ | ||
T18101 | 2745-2750 | Protein | denotes | NleH1 | ||
T18102 | 2783-2787 | Protein | denotes | RPS3 | ||
T18103 | 2917-2920 | Protein | denotes | IL8 | ||
T18104 | 2943-2948 | Protein | denotes | NleH1 | ||
T18105 | 2958-2963 | Negative_regulation | denotes | block | true | |
T18106 | 2970-2973 | Protein | denotes | p65 | ||
T18107 | 2974-2981 | Entity | denotes | nuclear | ||
T18108 | 2982-2995 | Localization | denotes | translocation | ||
T18109 | 3025-3028 | Protein | denotes | p65 | ||
T18110 | 3043-3047 | Protein | denotes | RPS3 | ||
T18111 | 3181-3191 | Negative_regulation | denotes | inhibiting | ||
T18112 | 3192-3196 | Protein | denotes | RPS3 | ||
T18113 | 3235-3240 | Protein | denotes | NleH1 | ||
T18114 | 3827-3835 | Negative_regulation | denotes | impeding | ||
T18115 | 3836-3840 | Protein | denotes | RPS3 | ||
T18116 | 3850-3858 | Regulation | denotes | altering | ||
T18117 | 3859-3862 | Protein | denotes | p65 | ||
T18118 | 3863-3870 | Entity | denotes | nuclear | ||
T18119 | 3871-3884 | Localization | denotes | translocation | ||
T18120 | 4114-4121 | Regulation | denotes | effects | ||
T18121 | 4142-4146 | Protein | denotes | RPS3 | ||
R14344 | T18035 | T18036 | themeOf | RPS3,translocate | ||
R14345 | T18036 | T18034 | themeOf | translocate,triggers | ||
R14346 | T18037 | T18036 | locationOf | nucleus,translocate | ||
R14347 | T18038 | T18039 | causeOf | IKKβ,mediated | ||
R14348 | T18039 | T18043 | causeOf | mediated,critical | ||
R14349 | T18040 | T18045 | themeOf | RPS3,import | ||
R14350 | T18041 | T18042 | themeOf | S209,phosphorylation | ||
R14351 | T18041 | T18040 | partOf | S209,RPS3 | ||
R14352 | T18042 | T18039 | themeOf | phosphorylation,mediated | ||
R14353 | T18044 | T18045 | locationOf | nuclear,import | ||
R14354 | T18045 | T18043 | themeOf | import,critical | ||
R14355 | T18049 | T18051 | causeOf | IKKβ,phosphorylated | ||
R14356 | T18050 | T18052 | causeOf | IKKα,phosphorylated | ||
R14357 | T18051 | T18055 | causeOf | phosphorylated,modulation | ||
R14358 | T18052 | T18054 | causeOf | phosphorylated,modulation | ||
R14359 | T18053 | T18051 | themeOf | RPS3,phosphorylated | ||
R14360 | T18053 | T18052 | themeOf | RPS3,phosphorylated | ||
R14361 | T18056 | T18058 | themeOf | RPS3,translocation | ||
R14362 | T18057 | T18058 | locationOf | nuclear,translocation | ||
R14363 | T18058 | T18055 | themeOf | translocation,modulation | ||
R14364 | T18058 | T18054 | themeOf | translocation,modulation | ||
R14365 | T18058 | T18059 | themeOf | translocation,via | ||
R14366 | T18061 | T18060 | themeOf | p65,phosphorylate | ||
R14367 | T18064 | T18062 | themeOf | IKKβ,bind | ||
R14368 | T18064 | T18063 | themeOf | IKKβ,phosphorylate | ||
R14369 | T18065 | T18066 | themeOf | IKKβ,bound | ||
R14370 | T18066 | T18067 | causeOf | bound,account for | ||
R14371 | T18068 | T18069 | themeOf | RPS3,phosphorylation | ||
R14372 | T18069 | T18067 | themeOf | phosphorylation,account for | ||
R14373 | T18073 | T18074 | causeOf | IKKβ,mediated | ||
R14374 | T18074 | T18078 | themeOf | mediated,modulated | ||
R14375 | T18076 | T18077 | themeOf | S209,phosphorylation | ||
R14376 | T18076 | T18075 | partOf | S209,RPS3 | ||
R14377 | T18077 | T18074 | themeOf | phosphorylation,mediated | ||
R14378 | T18079 | T18080 | themeOf | NleH1,binds | ||
R14379 | T18081 | T18080 | themeOf | RPS3,binds | ||
R14380 | T18082 | T18083 | causeOf | NleH1,inhibits | ||
R14381 | T18083 | T18086 | causeOf | inhibits,retarding | ||
R14382 | T18084 | T18085 | themeOf | RPS3,phosphorylation | ||
R14383 | T18084 | T18088 | themeOf | RPS3,translocation | ||
R14384 | T18085 | T18083 | themeOf | phosphorylation,inhibits | ||
R14385 | T18087 | T18088 | locationOf | nuclear,translocation | ||
R14386 | T18088 | T18086 | themeOf | translocation,retarding | ||
R14387 | T18091 | T18090 | themeOf | IKKβ,phosphorylate | ||
R14388 | T18093 | T18094 | causeOf | IKKβ,mediated | ||
R14389 | T18094 | T18092 | themeOf | mediated,inhibit | ||
R14390 | T18096 | T18097 | themeOf | S209,phosphorylation | ||
R14391 | T18096 | T18095 | partOf | S209,RPS3 | ||
R14392 | T18097 | T18094 | themeOf | phosphorylation,mediated | ||
R14393 | T18098 | T18099 | causeOf | NleH1,steer | ||
R14394 | T18100 | T18099 | themeOf | IKKβ,steer | ||
R14395 | T18104 | T18105 | causeOf | NleH1,block | ||
R14396 | T18106 | T18108 | themeOf | p65,translocation | ||
R14397 | T18107 | T18108 | locationOf | nuclear,translocation | ||
R14398 | T18108 | T18105 | themeOf | translocation,block | ||
R14399 | T18112 | T18111 | themeOf | RPS3,inhibiting | ||
R14400 | T18113 | T18111 | causeOf | NleH1,inhibiting | ||
R14401 | T18115 | T18114 | themeOf | RPS3,impeding | ||
R14402 | T18117 | T18119 | themeOf | p65,translocation | ||
R14403 | T18118 | T18119 | locationOf | nuclear,translocation | ||
R14404 | T18119 | T18116 | themeOf | translocation,altering | ||
R14405 | T18121 | T18120 | themeOf | RPS3,effects |
test2
Id | Subject | Object | Predicate | Lexical cue | Negation | Speculation |
---|---|---|---|---|---|---|
T17951 | 11-15 | Protein | denotes | RPS3 | true | |
T17952 | 180-188 | Positive_regulation | denotes | triggers | ||
T17953 | 189-193 | Protein | denotes | RPS3 | ||
T17954 | 197-208 | Localization | denotes | translocate | ||
T17955 | 279-283 | Protein | denotes | IKKβ | ||
T17956 | 284-292 | Positive_regulation | denotes | mediated | ||
T17957 | 293-297 | Protein | denotes | RPS3 | ||
T17958 | 298-302 | Entity | denotes | S209 | true | |
T17959 | 303-318 | Phosphorylation | denotes | phosphorylation | ||
T17960 | 370-377 | Entity | denotes | nuclear | ||
T17961 | 378-384 | Localization | denotes | import | ||
T17962 | 455-459 | Protein | denotes | IKKβ | ||
T17963 | 592-596 | Protein | denotes | RPS3 | ||
T17964 | 722-726 | Protein | denotes | IKKβ | ||
T17965 | 821-825 | Protein | denotes | IKKβ | ||
T17966 | 835-839 | Protein | denotes | IKKα | ||
T17967 | 841-855 | Phosphorylation | denotes | phosphorylated | true | |
T17968 | 856-860 | Protein | denotes | RPS3 | ||
T17969 | 906-916 | Regulation | denotes | modulation | ||
T17970 | 921-925 | Protein | denotes | RPS3 | ||
T17971 | 926-933 | Entity | denotes | nuclear | ||
T17972 | 934-947 | Localization | denotes | translocation | ||
T17973 | 949-952 | Positive_regulation | denotes | via | ||
T17974 | 969-979 | Binding | denotes | engagement | ||
T17975 | 1041-1054 | Phosphorylation | denotes | phosphorylate | ||
T17976 | 1055-1058 | Protein | denotes | p65 | ||
T17977 | 1066-1070 | Binding | denotes | bind | true | |
T17978 | 1078-1091 | Phosphorylation | denotes | phosphorylate | ||
T17979 | 1092-1096 | Protein | denotes | IKKβ | ||
T17980 | 1150-1154 | Protein | denotes | IKKβ | ||
T17981 | 1155-1160 | Binding | denotes | bound | ||
T17982 | 1171-1178 | Regulation | denotes | account | true | |
T17983 | 1196-1200 | Protein | denotes | RPS3 | ||
T17984 | 1201-1216 | Phosphorylation | denotes | phosphorylation | ||
T17985 | 1252-1256 | Protein | denotes | IKKβ | ||
T17986 | 1314-1318 | Protein | denotes | RPS3 | ||
T17987 | 1540-1544 | Protein | denotes | RPS3 | ||
T17988 | 1693-1697 | Protein | denotes | IKKβ | ||
T17989 | 1698-1706 | Positive_regulation | denotes | mediated | ||
T17990 | 1707-1711 | Protein | denotes | RPS3 | ||
T17991 | 1712-1716 | Entity | denotes | S209 | ||
T17992 | 1717-1732 | Phosphorylation | denotes | phosphorylation | ||
T17993 | 1837-1842 | Protein | denotes | NleH1 | ||
T17994 | 1856-1861 | Binding | denotes | binds | ||
T17995 | 1865-1869 | Protein | denotes | RPS3 | ||
T17996 | 2003-2008 | Protein | denotes | NleH1 | ||
T17997 | 2021-2029 | Negative_regulation | denotes | inhibits | ||
T17998 | 2030-2034 | Protein | denotes | RPS3 | ||
T17999 | 2035-2050 | Phosphorylation | denotes | phosphorylation | ||
T18000 | 2071-2078 | Entity | denotes | nuclear | ||
T18001 | 2079-2092 | Localization | denotes | translocation | ||
T18002 | 2173-2178 | Protein | denotes | NleH1 | ||
T18003 | 2196-2209 | Phosphorylation | denotes | phosphorylate | ||
T18004 | 2210-2214 | Protein | denotes | IKKβ | ||
T18005 | 2240-2248 | Positive_regulation | denotes | required | ||
T18006 | 2252-2259 | Negative_regulation | denotes | inhibit | ||
T18007 | 2260-2264 | Protein | denotes | IKKβ | ||
T18008 | 2265-2273 | Positive_regulation | denotes | mediated | ||
T18009 | 2274-2278 | Protein | denotes | RPS3 | ||
T18010 | 2279-2283 | Entity | denotes | S209 | ||
T18011 | 2284-2299 | Phosphorylation | denotes | phosphorylation | ||
T18012 | 2430-2435 | Protein | denotes | NleH1 | ||
T18013 | 2474-2478 | Protein | denotes | IKKβ | ||
T18014 | 2745-2750 | Protein | denotes | NleH1 | ||
T18015 | 2783-2787 | Protein | denotes | RPS3 | ||
T18016 | 2917-2920 | Protein | denotes | IL8 | ||
T18017 | 2943-2948 | Protein | denotes | NleH1 | ||
T18018 | 2958-2963 | Negative_regulation | denotes | block | ||
T18019 | 2970-2973 | Protein | denotes | p65 | ||
T18020 | 2974-2981 | Entity | denotes | nuclear | ||
T18021 | 2982-2995 | Localization | denotes | translocation | ||
T18022 | 3025-3028 | Protein | denotes | p65 | ||
T18023 | 3029-3038 | Regulation | denotes | dependent | ||
T18024 | 3043-3047 | Protein | denotes | RPS3 | ||
T18025 | 3181-3191 | Negative_regulation | denotes | inhibiting | ||
T18026 | 3192-3196 | Protein | denotes | RPS3 | ||
T18027 | 3235-3240 | Protein | denotes | NleH1 | ||
T18028 | 3836-3840 | Protein | denotes | RPS3 | ||
T18029 | 3859-3862 | Protein | denotes | p65 | ||
T18030 | 3863-3870 | Entity | denotes | nuclear | ||
T18031 | 3871-3884 | Localization | denotes | translocation | ||
T18032 | 4142-4146 | Protein | denotes | RPS3 | ||
R14294 | T17953 | T17954 | themeOf | RPS3,translocate | ||
R14295 | T17954 | T17952 | themeOf | translocate,triggers | ||
R14296 | T17955 | T17956 | causeOf | IKKβ,mediated | ||
R14297 | T17957 | T17961 | themeOf | RPS3,import | ||
R14298 | T17958 | T17957 | partOf | S209,RPS3 | ||
R14299 | T17958 | T17959 | themeOf | S209,phosphorylation | ||
R14300 | T17959 | T17956 | themeOf | phosphorylation,mediated | ||
R14301 | T17960 | T17961 | locationOf | nuclear,import | ||
R14302 | T17965 | T17967 | causeOf | IKKβ,phosphorylated | ||
R14303 | T17966 | T17967 | causeOf | IKKα,phosphorylated | ||
R14304 | T17968 | T17967 | themeOf | RPS3,phosphorylated | ||
R14305 | T17970 | T17972 | themeOf | RPS3,translocation | ||
R14306 | T17971 | T17972 | locationOf | nuclear,translocation | ||
R14307 | T17972 | T17973 | themeOf | translocation,via | ||
R14308 | T17972 | T17969 | themeOf | translocation,modulation | ||
R14309 | T17974 | T17969 | causeOf | engagement,modulation | ||
R14310 | T17976 | T17975 | themeOf | p65,phosphorylate | ||
R14311 | T17976 | T17977 | themeOf | p65,bind | ||
R14312 | T17979 | T17977 | themeOf | IKKβ,bind | ||
R14313 | T17979 | T17978 | themeOf | IKKβ,phosphorylate | ||
R14314 | T17980 | T17982 | causeOf | IKKβ,account | ||
R14315 | T17980 | T17981 | themeOf | IKKβ,bound | ||
R14316 | T17981 | T17982 | causeOf | bound,account | ||
R14317 | T17983 | T17984 | themeOf | RPS3,phosphorylation | ||
R14318 | T17984 | T17982 | themeOf | phosphorylation,account | ||
R14319 | T17988 | T17989 | causeOf | IKKβ,mediated | ||
R14320 | T17991 | T17990 | partOf | S209,RPS3 | ||
R14321 | T17991 | T17992 | themeOf | S209,phosphorylation | ||
R14322 | T17992 | T17989 | themeOf | phosphorylation,mediated | ||
R14323 | T17993 | T17994 | themeOf | NleH1,binds | ||
R14324 | T17995 | T17994 | themeOf | RPS3,binds | ||
R14325 | T17996 | T17997 | causeOf | NleH1,inhibits | ||
R14326 | T17998 | T18001 | themeOf | RPS3,translocation | ||
R14327 | T17998 | T17999 | themeOf | RPS3,phosphorylation | ||
R14328 | T17999 | T17997 | themeOf | phosphorylation,inhibits | ||
R14329 | T18000 | T18001 | locationOf | nuclear,translocation | ||
R14330 | T18004 | T18003 | themeOf | IKKβ,phosphorylate | ||
R14331 | T18007 | T18008 | causeOf | IKKβ,mediated | ||
R14332 | T18008 | T18006 | themeOf | mediated,inhibit | ||
R14333 | T18010 | T18009 | partOf | S209,RPS3 | ||
R14334 | T18010 | T18011 | themeOf | S209,phosphorylation | ||
R14335 | T18011 | T18008 | themeOf | phosphorylation,mediated | ||
R14336 | T18017 | T18018 | causeOf | NleH1,block | ||
R14337 | T18019 | T18021 | themeOf | p65,translocation | ||
R14338 | T18020 | T18021 | locationOf | nuclear,translocation | ||
R14339 | T18021 | T18018 | themeOf | translocation,block | ||
R14340 | T18026 | T18025 | themeOf | RPS3,inhibiting | ||
R14341 | T18027 | T18025 | causeOf | NleH1,inhibiting | ||
R14342 | T18029 | T18031 | themeOf | p65,translocation | ||
R14343 | T18030 | T18031 | locationOf | nuclear,translocation |