PMC:3062687 / 19790-20091
Annnotations
bionlp-st-ge-2016-uniprot
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pmc-enju-pas
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bionlp-st-ge-2016-spacy-parsed
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GO-BP
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sentences
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events-check-again
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bionlp-st-ge-2016-reference-tees
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bionlp-st-ge-2016-reference
{"project":"bionlp-st-ge-2016-reference","denotations":[{"id":"T14715","span":{"begin":34,"end":39},"obj":"Protein"},{"id":"T14716","span":{"begin":40,"end":48},"obj":"Negative_regulation"},{"id":"T14717","span":{"begin":49,"end":53},"obj":"Protein"},{"id":"T14718","span":{"begin":54,"end":58},"obj":"Entity"},{"id":"T14719","span":{"begin":59,"end":74},"obj":"Phosphorylation"},{"id":"T14720","span":{"begin":144,"end":153},"obj":"Protein"},{"id":"T14721","span":{"begin":175,"end":184},"obj":"Protein"},{"id":"T14722","span":{"begin":218,"end":223},"obj":"Protein"},{"id":"T14723","span":{"begin":227,"end":245},"obj":"Phosphorylation"},{"id":"T14724","span":{"begin":254,"end":259},"obj":"Entity"},{"id":"T14725","span":{"begin":266,"end":271},"obj":"Protein"},{"id":"T14726","span":{"begin":272,"end":283},"obj":"Negative_regulation"}],"relations":[{"id":"R11793","pred":"partOf","subj":"T14718","obj":"T14717"},{"id":"R11794","pred":"themeOf","subj":"T14719","obj":"T14716"},{"id":"R11795","pred":"themeOf","subj":"T14722","obj":"T14723"},{"id":"R11796","pred":"causeOf","subj":"T14724","obj":"T14726"},{"id":"R11797","pred":"partOf","subj":"T14724","obj":"T14725"},{"id":"R11798","pred":"themeOf","subj":"T14725","obj":"T14726"},{"id":"R11791","pred":"causeOf","subj":"T14715","obj":"T14716"},{"id":"R11792","pred":"themeOf","subj":"T14718","obj":"T14719"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"To explore the mechanism by which NleH1 inhibits RPS3 S209 phosphorylation, we first performed an in vitro kinase assay with purified wild-type His-NleH1 protein and a mutant His-NleH1 (K159A) protein, confirming that NleH1 is autophosphorylated and the K159A is an NleH1 kinase-dead mutant (Fig. 7a)."}
test2
{"project":"test2","denotations":[{"id":"T14529","span":{"begin":34,"end":39},"obj":"Protein"},{"id":"T14530","span":{"begin":40,"end":48},"obj":"Negative_regulation"},{"id":"T14531","span":{"begin":49,"end":53},"obj":"Protein"},{"id":"T14532","span":{"begin":54,"end":58},"obj":"Entity"},{"id":"T14533","span":{"begin":59,"end":74},"obj":"Phosphorylation"},{"id":"T14534","span":{"begin":144,"end":153},"obj":"Protein"},{"id":"T14535","span":{"begin":175,"end":184},"obj":"Protein"},{"id":"T14536","span":{"begin":218,"end":223},"obj":"Protein"},{"id":"T14537","span":{"begin":227,"end":245},"obj":"Phosphorylation"},{"id":"T14538","span":{"begin":266,"end":271},"obj":"Protein"},{"id":"T14539","span":{"begin":272,"end":283},"obj":"Negative_regulation"}],"relations":[{"id":"R11660","pred":"causeOf","subj":"T14529","obj":"T14530"},{"id":"R11661","pred":"themeOf","subj":"T14532","obj":"T14533"},{"id":"R11662","pred":"partOf","subj":"T14532","obj":"T14531"},{"id":"R11663","pred":"themeOf","subj":"T14533","obj":"T14530"},{"id":"R11664","pred":"themeOf","subj":"T14536","obj":"T14539"},{"id":"R11665","pred":"themeOf","subj":"T14536","obj":"T14537"},{"id":"R11666","pred":"themeOf","subj":"T14538","obj":"T14539"}],"attributes":[{"id":"M486","pred":"Speculation","subj":"T14531","obj":"true"}],"text":"To explore the mechanism by which NleH1 inhibits RPS3 S209 phosphorylation, we first performed an in vitro kinase assay with purified wild-type His-NleH1 protein and a mutant His-NleH1 (K159A) protein, confirming that NleH1 is autophosphorylated and the K159A is an NleH1 kinase-dead mutant (Fig. 7a)."}