PMC:3023298 / 73035-73634 JSONTXT

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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/3023298","sourcedb":"PMC","sourceid":"3023298","source_url":"https://www.ncbi.nlm.nih.gov/pmc/3023298","text":"Brain atrophy and neurodegeneration in people with AD. Midsagittal views (center pictures) of the brains from an 85-year-old individual with AD and an 86-year-old normal control individual. The microscopic neuropathological hallmarks of AD are senile plaques (scale bar = 200 μm), neurofibrillary tangles (NFTs, scale bar = 50 μm.), and neuronal cell death determined by transferase-mediated biotin-dUTP nick-end labeling (TUNEL, brown nuclear staining, open arrows, scale bars = 10 μm) as seen in the hippocampus CA1 and in subcortical regions such as the thalamic lateral geniculate nucleus (LGN).","tracks":[]}