PMC:2952583 / 19692-21852 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/2952583","sourcedb":"PMC","sourceid":"2952583","source_url":"https://www.ncbi.nlm.nih.gov/pmc/2952583","text":"Table 2 Odds Ratios for Preeclampsia According to Circulating Angiogenic Factors Measured in Samples Collected at Study Entry.*\nDiabetes\nControls(N = 148) Preeclampsia(N = 46) Unadjusted OR[95% CI] Adjusted OR[95% CI] †\nsFlt1 (ng/ml) 3.60±2.02 3.75±2.33 0.98 [0.64,1.51] 0.98 [0.63,1.53]\nsEng (ng/ml) 5.31±1.58 5.75±2.29 1.62 [0.74,3.54] 1.66 [0.70,3.92]\nPIGF (pg/ml) 151.14±144.55 156.74±147.51 1.02 [0.78,1.32] 0.59 [0.36,0.95]\nsFlt1 + sEng/PIGF 124.94±135.34 124.36±111.64 1.03 [0.80,1.32] 1.61 [1.07,2.48]\nChronic Hypertension\nControls(N = 235) Preeclampsia(N = 78) Unadjusted OR[95% CI] Adjusted OR[95% CI] †\nsFlt1 (ng/ml) 3.68±3.66 3.83±2.91 1.09 [0.79,1.49] 1.16 [0.83,1.63]\nsEng (ng/ml) 5.58±5.73 6.05±3.60 1.51 [0.96,2.39] 1.60 [1.01,2.57]\nPIGF (pg/ml) 222.54±236.67 191.61±154.19 0.92 [0.74,1.13] 0.96 [0.71,1.29]\nsFlt1 + sEng/PIGF 96.65±214.75 123.71±216.91 1.13 [0.94,1.36] 1.13 [0.90,1.41]\nMultifetal Gestation\nControls(N = 195) Preeclampsia(N = 39) Unadjusted OR[95% CI] Adjusted OR[95% CI] †\nsFlt1 (ng/ml) 5.95±2.47 7.33±5.42 1.55 [0.93,2.68] 2.07 [1.15,3.89]\nsEng (ng/ml) 7.04±2.70 8.54±4.50 2.14 [1.14,4.05] 2.98 [1.44,6.36]\nPIGF (pg/ml) 554.73±388.10 386.10±318.17 0.61 [0.44,0.82] 0.50 [0.30,0.82]\nsFlt1 + sEng/PIGF 40.37±43.20 75.31±67.62 1.80 [1.35,2.44] 2.18 [1.46,3.32]\nPrevious Preeclampsia\nControls(N = 202) Preeclampsia(N = 50) Unadjusted OR[95% CI] Adjusted OR[95% CI] †\nsFlt1 (ng/ml) 3.32±1.84 3.16±1.72 0.86 [0.60,1.32] 0.96 [0.61,1.52]\nsEng (ng/ml) 5.52±4.93 5.60±2.71 1.25 [0.72,2.12] 1.41 [0.80,2.46]\nPIGF (pg/ml) 231.58±218.94 191.35±159.20 0.89 [0.72,1.11] 0.93 [0.67,1.36]\nsFlt1 + sEng/PIGF 100.70±207.02 122.37±186.63 1.13 [0.92,1.38] 1.15 [0.83,1.56]\n*Data are presented as mean ± standard deviation. OR denotes odds ratio, CI confidence interval. Odds ratios represent the odds of developing preeclampsia for a two-fold increase of the factor among preeclamptic subjects compared to controls.\n† Odds ratios were adjusted for gestational age at sample collection, smoking, maternal age, race or ethnic group, body mass index and treatment group.","divisions":[{"label":"label","span":{"begin":0,"end":7}},{"label":"caption","span":{"begin":9,"end":128}},{"label":"title","span":{"begin":9,"end":128}},{"label":"table","span":{"begin":129,"end":529}},{"label":"tr","span":{"begin":129,"end":137}},{"label":"td","span":{"begin":129,"end":137}},{"label":"tr","span":{"begin":138,"end":223}},{"label":"td","span":{"begin":138,"end":155}},{"label":"td","span":{"begin":157,"end":177}},{"label":"td","span":{"begin":179,"end":200}},{"label":"td","span":{"begin":202,"end":223}},{"label":"tr","span":{"begin":224,"end":295}},{"label":"td","span":{"begin":224,"end":237}},{"label":"td","span":{"begin":239,"end":248}},{"label":"td","span":{"begin":250,"end":259}},{"label":"td","span":{"begin":261,"end":277}},{"label":"td","span":{"begin":279,"end":295}},{"label":"tr","span":{"begin":296,"end":366}},{"label":"td","span":{"begin":296,"end":308}},{"label":"td","span":{"begin":310,"end":319}},{"label":"td","span":{"begin":321,"end":330}},{"label":"td","span":{"begin":332,"end":348}},{"label":"td","span":{"begin":350,"end":366}},{"label":"tr","span":{"begin":367,"end":445}},{"label":"td","span":{"begin":367,"end":379}},{"label":"td","span":{"begin":381,"end":394}},{"label":"td","span":{"begin":396,"end":409}},{"label":"td","span":{"begin":411,"end":427}},{"label":"td","span":{"begin":429,"end":445}},{"label":"tr","span":{"begin":446,"end":529}},{"label":"td","span":{"begin":446,"end":463}},{"label":"td","span":{"begin":465,"end":478}},{"label":"td","span":{"begin":480,"end":493}},{"label":"td","span":{"begin":495,"end":511}},{"label":"td","span":{"begin":513,"end":529}},{"label":"table","span":{"begin":530,"end":941}},{"label":"tr","span":{"begin":530,"end":550}},{"label":"td","span":{"begin":530,"end":550}},{"label":"tr","span":{"begin":551,"end":636}},{"label":"td","span":{"begin":551,"end":568}},{"label":"td","span":{"begin":570,"end":590}},{"label":"td","span":{"begin":592,"end":613}},{"label":"td","span":{"begin":615,"end":636}},{"label":"tr","span":{"begin":637,"end":708}},{"label":"td","span":{"begin":637,"end":650}},{"label":"td","span":{"begin":652,"end":661}},{"label":"td","span":{"begin":663,"end":672}},{"label":"td","span":{"begin":674,"end":690}},{"label":"td","span":{"begin":692,"end":708}},{"label":"tr","span":{"begin":709,"end":779}},{"label":"td","span":{"begin":709,"end":721}},{"label":"td","span":{"begin":723,"end":732}},{"label":"td","span":{"begin":734,"end":743}},{"label":"td","span":{"begin":745,"end":761}},{"label":"td","span":{"begin":763,"end":779}},{"label":"tr","span":{"begin":780,"end":858}},{"label":"td","span":{"begin":780,"end":792}},{"label":"td","span":{"begin":794,"end":807}},{"label":"td","span":{"begin":809,"end":822}},{"label":"td","span":{"begin":824,"end":840}},{"label":"td","span":{"begin":842,"end":858}},{"label":"tr","span":{"begin":859,"end":941}},{"label":"td","span":{"begin":859,"end":876}},{"label":"td","span":{"begin":878,"end":890}},{"label":"td","span":{"begin":892,"end":905}},{"label":"td","span":{"begin":907,"end":923}},{"label":"td","span":{"begin":925,"end":941}},{"label":"table","span":{"begin":942,"end":1350}},{"label":"tr","span":{"begin":942,"end":962}},{"label":"td","span":{"begin":942,"end":962}},{"label":"tr","span":{"begin":963,"end":1048}},{"label":"td","span":{"begin":963,"end":980}},{"label":"td","span":{"begin":982,"end":1002}},{"label":"td","span":{"begin":1004,"end":1025}},{"label":"td","span":{"begin":1027,"end":1048}},{"label":"tr","span":{"begin":1049,"end":1120}},{"label":"td","span":{"begin":1049,"end":1062}},{"label":"td","span":{"begin":1064,"end":1073}},{"label":"td","span":{"begin":1075,"end":1084}},{"label":"td","span":{"begin":1086,"end":1102}},{"label":"td","span":{"begin":1104,"end":1120}},{"label":"tr","span":{"begin":1121,"end":1191}},{"label":"td","span":{"begin":1121,"end":1133}},{"label":"td","span":{"begin":1135,"end":1144}},{"label":"td","span":{"begin":1146,"end":1155}},{"label":"td","span":{"begin":1157,"end":1173}},{"label":"td","span":{"begin":1175,"end":1191}},{"label":"tr","span":{"begin":1192,"end":1270}},{"label":"td","span":{"begin":1192,"end":1204}},{"label":"td","span":{"begin":1206,"end":1219}},{"label":"td","span":{"begin":1221,"end":1234}},{"label":"td","span":{"begin":1236,"end":1252}},{"label":"td","span":{"begin":1254,"end":1270}},{"label":"tr","span":{"begin":1271,"end":1350}},{"label":"td","span":{"begin":1271,"end":1288}},{"label":"td","span":{"begin":1290,"end":1301}},{"label":"td","span":{"begin":1303,"end":1314}},{"label":"td","span":{"begin":1316,"end":1332}},{"label":"td","span":{"begin":1334,"end":1350}},{"label":"table","span":{"begin":1351,"end":1764}},{"label":"tr","span":{"begin":1351,"end":1372}},{"label":"td","span":{"begin":1351,"end":1372}},{"label":"tr","span":{"begin":1373,"end":1458}},{"label":"td","span":{"begin":1373,"end":1390}},{"label":"td","span":{"begin":1392,"end":1412}},{"label":"td","span":{"begin":1414,"end":1435}},{"label":"td","span":{"begin":1437,"end":1458}},{"label":"tr","span":{"begin":1459,"end":1530}},{"label":"td","span":{"begin":1459,"end":1472}},{"label":"td","span":{"begin":1474,"end":1483}},{"label":"td","span":{"begin":1485,"end":1494}},{"label":"td","span":{"begin":1496,"end":1512}},{"label":"td","span":{"begin":1514,"end":1530}},{"label":"tr","span":{"begin":1531,"end":1601}},{"label":"td","span":{"begin":1531,"end":1543}},{"label":"td","span":{"begin":1545,"end":1554}},{"label":"td","span":{"begin":1556,"end":1565}},{"label":"td","span":{"begin":1567,"end":1583}},{"label":"td","span":{"begin":1585,"end":1601}},{"label":"tr","span":{"begin":1602,"end":1680}},{"label":"td","span":{"begin":1602,"end":1614}},{"label":"td","span":{"begin":1616,"end":1629}},{"label":"td","span":{"begin":1631,"end":1644}},{"label":"td","span":{"begin":1646,"end":1662}},{"label":"td","span":{"begin":1664,"end":1680}},{"label":"tr","span":{"begin":1681,"end":1764}},{"label":"td","span":{"begin":1681,"end":1698}},{"label":"td","span":{"begin":1700,"end":1713}},{"label":"td","span":{"begin":1715,"end":1728}},{"label":"td","span":{"begin":1730,"end":1746}},{"label":"td","span":{"begin":1748,"end":1764}},{"label":"footnote","span":{"begin":1765,"end":2007}},{"label":"p","span":{"begin":1765,"end":2007}},{"label":"label","span":{"begin":2008,"end":2009}}],"tracks":[]}