PMC:2948167 / 1173-2577 JSONTXT

{"project":"0_colil","denotations":[{"id":"20535613-17762736-42875","span":{"begin":1023,"end":1024},"obj":"17762736"}],"text":"Introduction\nFor brain pial arteriovenous malformations, too little is as of yet known concerning their aetiology, pathophysiology and natural history to truly and confidently give guidelines for their treatment. Both advances in diagnostic tools for pretreatment risk assessment and continuously improved treatment techniques such as catheterisation and embolisation materials will presumably change therapeutic risks and will therefore have an impact on the way we will manage these vascular malformations. Finally, the skills and experience of the physician performing the endovascular treatment have a profound impact on the patient’s outcome, which will therefore naturally vary from centre to centre.\nIn this article, we will nevertheless try to describe our current approach to pial arteriovenous brain malformations that is based on an attempt to relate the patient’s clinical findings to the underlying angioarchitecture in order to define angiographic targets related to the pertinent individual pathophysiology [1]. We will, therefore, first briefly describe a classification of vascular malformations in general, and of brain AVMs in particular, followed by a description of angioarchitectural points to consider when treating brain AVMs. In the last part of this article, we will describe our current concept of treatment, which has been coined “partial targeted” embolisation of brain AVMs."}

{"project":"2_test","denotations":[{"id":"20535613-17762736-29352748","span":{"begin":1023,"end":1024},"obj":"17762736"}],"text":"Introduction\nFor brain pial arteriovenous malformations, too little is as of yet known concerning their aetiology, pathophysiology and natural history to truly and confidently give guidelines for their treatment. Both advances in diagnostic tools for pretreatment risk assessment and continuously improved treatment techniques such as catheterisation and embolisation materials will presumably change therapeutic risks and will therefore have an impact on the way we will manage these vascular malformations. Finally, the skills and experience of the physician performing the endovascular treatment have a profound impact on the patient’s outcome, which will therefore naturally vary from centre to centre.\nIn this article, we will nevertheless try to describe our current approach to pial arteriovenous brain malformations that is based on an attempt to relate the patient’s clinical findings to the underlying angioarchitecture in order to define angiographic targets related to the pertinent individual pathophysiology [1]. We will, therefore, first briefly describe a classification of vascular malformations in general, and of brain AVMs in particular, followed by a description of angioarchitectural points to consider when treating brain AVMs. In the last part of this article, we will describe our current concept of treatment, which has been coined “partial targeted” embolisation of brain AVMs."}

{"project":"TEST0","denotations":[{"id":"20535613-238-243-42875","span":{"begin":1023,"end":1024},"obj":"[\"17762736\"]"}],"text":"Introduction\nFor brain pial arteriovenous malformations, too little is as of yet known concerning their aetiology, pathophysiology and natural history to truly and confidently give guidelines for their treatment. Both advances in diagnostic tools for pretreatment risk assessment and continuously improved treatment techniques such as catheterisation and embolisation materials will presumably change therapeutic risks and will therefore have an impact on the way we will manage these vascular malformations. Finally, the skills and experience of the physician performing the endovascular treatment have a profound impact on the patient’s outcome, which will therefore naturally vary from centre to centre.\nIn this article, we will nevertheless try to describe our current approach to pial arteriovenous brain malformations that is based on an attempt to relate the patient’s clinical findings to the underlying angioarchitecture in order to define angiographic targets related to the pertinent individual pathophysiology [1]. We will, therefore, first briefly describe a classification of vascular malformations in general, and of brain AVMs in particular, followed by a description of angioarchitectural points to consider when treating brain AVMs. In the last part of this article, we will describe our current concept of treatment, which has been coined “partial targeted” embolisation of brain AVMs."}

{"project":"MyTest","denotations":[{"id":"20535613-17762736-29352748","span":{"begin":1023,"end":1024},"obj":"17762736"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"Introduction\nFor brain pial arteriovenous malformations, too little is as of yet known concerning their aetiology, pathophysiology and natural history to truly and confidently give guidelines for their treatment. Both advances in diagnostic tools for pretreatment risk assessment and continuously improved treatment techniques such as catheterisation and embolisation materials will presumably change therapeutic risks and will therefore have an impact on the way we will manage these vascular malformations. Finally, the skills and experience of the physician performing the endovascular treatment have a profound impact on the patient’s outcome, which will therefore naturally vary from centre to centre.\nIn this article, we will nevertheless try to describe our current approach to pial arteriovenous brain malformations that is based on an attempt to relate the patient’s clinical findings to the underlying angioarchitecture in order to define angiographic targets related to the pertinent individual pathophysiology [1]. We will, therefore, first briefly describe a classification of vascular malformations in general, and of brain AVMs in particular, followed by a description of angioarchitectural points to consider when treating brain AVMs. In the last part of this article, we will describe our current concept of treatment, which has been coined “partial targeted” embolisation of brain AVMs."}