PMC:2948165 / 16158-18802 JSONTXT

{"project":"TEST0","denotations":[{"id":"20585784-229-235-46871","span":{"begin":577,"end":579},"obj":"[\"16463302\"]"}],"text":"One could criticize MRI because in most MRI scanners, subjects are studied in a non-physiological body position, i.e., supine instead of upright or seated, which might cause a different meal distribution inside the stomach, which might influence gastric physiology (Fig. 5). Several studies were aimed at evaluation of these possible disadvantages of MRI as compared to other validated examination methods. Treier et al. determined the effect of the right decubitus lying body position on relevant parameters of human gastric motor function in healthy volunteers (see Fig. 6) [18]. In this study, postprandial gastric function after ingestion of a solid/liquid meal was assessed in volunteers in the right decubitus position and seated position. Stomach and intragastric air volume, intragastric meal distribution, gastric emptying and gastric peristalsis were compared between the right decubitus position and seated position. It was shown that body position did not affect gastric relaxation and initial gastric volumes. Postprandial stomach volume and gastric activity were also similar. Meal emptying showed different characteristics, resulting in a significant but small difference in meal volume (see Fig. 6) that could have been induced by posture-dependent vagal activity. This study is valuable because it confirmed that MRI in the right decubitus position is a reliable imaging technique for assessing gastrointestinal physiology and that results from MRI studies in the right decubitus position can be compared to studies performed in the sitting position. This is a solution to the fact that MRI in the sitting position is not widely possible to perform.\nFig. 5 a Left: Volunteer in RP inside the 1.5-T whole-body MRI system. Rectangular surface coils were fixed around the abdomen. Right: Three sagittal MR image slices (two proximal and one distal) of a volume scan in RP with outlined stomach wall. Air and meal are indicated in the MR images by arrows (F: feet, H: head, A: anterior, P: posterior). b Left: Volunteer sitting inside the 0.5-T open-configuration MRI system. A send-receive coil was fixed around the abdomen. Right: Three sagittal MR image slices (two proximal and one distal) of a volume scan in SP with outlined stomach wall. Air and meal are indicated in the MR images by arrows (F: feet, H: head, A: anterior, P: posterior)\nFig. 6 Normalized gastric emptying curves (percentage of remaining meal volume in the stomach) for RP (black) and SP (gray). Data are expressed as the median (interquartile range). A divergence of the emptying curves is observed, especially during the first 30 min after meal ingestion"}

{"project":"0_colil","denotations":[{"id":"20585784-16463302-46871","span":{"begin":577,"end":579},"obj":"16463302"}],"text":"One could criticize MRI because in most MRI scanners, subjects are studied in a non-physiological body position, i.e., supine instead of upright or seated, which might cause a different meal distribution inside the stomach, which might influence gastric physiology (Fig. 5). Several studies were aimed at evaluation of these possible disadvantages of MRI as compared to other validated examination methods. Treier et al. determined the effect of the right decubitus lying body position on relevant parameters of human gastric motor function in healthy volunteers (see Fig. 6) [18]. In this study, postprandial gastric function after ingestion of a solid/liquid meal was assessed in volunteers in the right decubitus position and seated position. Stomach and intragastric air volume, intragastric meal distribution, gastric emptying and gastric peristalsis were compared between the right decubitus position and seated position. It was shown that body position did not affect gastric relaxation and initial gastric volumes. Postprandial stomach volume and gastric activity were also similar. Meal emptying showed different characteristics, resulting in a significant but small difference in meal volume (see Fig. 6) that could have been induced by posture-dependent vagal activity. This study is valuable because it confirmed that MRI in the right decubitus position is a reliable imaging technique for assessing gastrointestinal physiology and that results from MRI studies in the right decubitus position can be compared to studies performed in the sitting position. This is a solution to the fact that MRI in the sitting position is not widely possible to perform.\nFig. 5 a Left: Volunteer in RP inside the 1.5-T whole-body MRI system. Rectangular surface coils were fixed around the abdomen. Right: Three sagittal MR image slices (two proximal and one distal) of a volume scan in RP with outlined stomach wall. Air and meal are indicated in the MR images by arrows (F: feet, H: head, A: anterior, P: posterior). b Left: Volunteer sitting inside the 0.5-T open-configuration MRI system. A send-receive coil was fixed around the abdomen. Right: Three sagittal MR image slices (two proximal and one distal) of a volume scan in SP with outlined stomach wall. Air and meal are indicated in the MR images by arrows (F: feet, H: head, A: anterior, P: posterior)\nFig. 6 Normalized gastric emptying curves (percentage of remaining meal volume in the stomach) for RP (black) and SP (gray). Data are expressed as the median (interquartile range). A divergence of the emptying curves is observed, especially during the first 30 min after meal ingestion"}

{"project":"2_test","denotations":[{"id":"20585784-16463302-29356007","span":{"begin":577,"end":579},"obj":"16463302"}],"text":"One could criticize MRI because in most MRI scanners, subjects are studied in a non-physiological body position, i.e., supine instead of upright or seated, which might cause a different meal distribution inside the stomach, which might influence gastric physiology (Fig. 5). Several studies were aimed at evaluation of these possible disadvantages of MRI as compared to other validated examination methods. Treier et al. determined the effect of the right decubitus lying body position on relevant parameters of human gastric motor function in healthy volunteers (see Fig. 6) [18]. In this study, postprandial gastric function after ingestion of a solid/liquid meal was assessed in volunteers in the right decubitus position and seated position. Stomach and intragastric air volume, intragastric meal distribution, gastric emptying and gastric peristalsis were compared between the right decubitus position and seated position. It was shown that body position did not affect gastric relaxation and initial gastric volumes. Postprandial stomach volume and gastric activity were also similar. Meal emptying showed different characteristics, resulting in a significant but small difference in meal volume (see Fig. 6) that could have been induced by posture-dependent vagal activity. This study is valuable because it confirmed that MRI in the right decubitus position is a reliable imaging technique for assessing gastrointestinal physiology and that results from MRI studies in the right decubitus position can be compared to studies performed in the sitting position. This is a solution to the fact that MRI in the sitting position is not widely possible to perform.\nFig. 5 a Left: Volunteer in RP inside the 1.5-T whole-body MRI system. Rectangular surface coils were fixed around the abdomen. Right: Three sagittal MR image slices (two proximal and one distal) of a volume scan in RP with outlined stomach wall. Air and meal are indicated in the MR images by arrows (F: feet, H: head, A: anterior, P: posterior). b Left: Volunteer sitting inside the 0.5-T open-configuration MRI system. A send-receive coil was fixed around the abdomen. Right: Three sagittal MR image slices (two proximal and one distal) of a volume scan in SP with outlined stomach wall. Air and meal are indicated in the MR images by arrows (F: feet, H: head, A: anterior, P: posterior)\nFig. 6 Normalized gastric emptying curves (percentage of remaining meal volume in the stomach) for RP (black) and SP (gray). Data are expressed as the median (interquartile range). A divergence of the emptying curves is observed, especially during the first 30 min after meal ingestion"}

{"project":"MyTest","denotations":[{"id":"20585784-16463302-29356007","span":{"begin":577,"end":579},"obj":"16463302"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"One could criticize MRI because in most MRI scanners, subjects are studied in a non-physiological body position, i.e., supine instead of upright or seated, which might cause a different meal distribution inside the stomach, which might influence gastric physiology (Fig. 5). Several studies were aimed at evaluation of these possible disadvantages of MRI as compared to other validated examination methods. Treier et al. determined the effect of the right decubitus lying body position on relevant parameters of human gastric motor function in healthy volunteers (see Fig. 6) [18]. In this study, postprandial gastric function after ingestion of a solid/liquid meal was assessed in volunteers in the right decubitus position and seated position. Stomach and intragastric air volume, intragastric meal distribution, gastric emptying and gastric peristalsis were compared between the right decubitus position and seated position. It was shown that body position did not affect gastric relaxation and initial gastric volumes. Postprandial stomach volume and gastric activity were also similar. Meal emptying showed different characteristics, resulting in a significant but small difference in meal volume (see Fig. 6) that could have been induced by posture-dependent vagal activity. This study is valuable because it confirmed that MRI in the right decubitus position is a reliable imaging technique for assessing gastrointestinal physiology and that results from MRI studies in the right decubitus position can be compared to studies performed in the sitting position. This is a solution to the fact that MRI in the sitting position is not widely possible to perform.\nFig. 5 a Left: Volunteer in RP inside the 1.5-T whole-body MRI system. Rectangular surface coils were fixed around the abdomen. Right: Three sagittal MR image slices (two proximal and one distal) of a volume scan in RP with outlined stomach wall. Air and meal are indicated in the MR images by arrows (F: feet, H: head, A: anterior, P: posterior). b Left: Volunteer sitting inside the 0.5-T open-configuration MRI system. A send-receive coil was fixed around the abdomen. Right: Three sagittal MR image slices (two proximal and one distal) of a volume scan in SP with outlined stomach wall. Air and meal are indicated in the MR images by arrows (F: feet, H: head, A: anterior, P: posterior)\nFig. 6 Normalized gastric emptying curves (percentage of remaining meal volume in the stomach) for RP (black) and SP (gray). Data are expressed as the median (interquartile range). A divergence of the emptying curves is observed, especially during the first 30 min after meal ingestion"}