PMC:2948162 / 16951-17986
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2948162","sourcedb":"PMC","sourceid":"2948162","source_url":"https://www.ncbi.nlm.nih.gov/pmc/2948162","text":"T2W CMR is capable of detecting myocardial oedema as regions of increased signal intensity due to prolongation of T2 relaxation time as a consequences of increased tissue free water content [18]. IMH is thought to be caused by leakage of blood out of severely injured microvasculature into the interstitium that can be depicted as a central area of low signal intensity (SI) within the oedematous area on T2W CMR. This low SI is explained by local field heterogeneities due to the paramagnetic effects of blood degradation products such as deoxyhaemoglobin, which shorten the T2 relaxation time [10]. In two case reports, Basso et al. demonstrated a good correlation among the location, spatial extent, and shape of IMH on CMR and histopathology [8]. Because of its excellent spatial resolution and high contrast, LGE CMR accurately assesses the extent of infarction and MVO [19]. Combined with T2W CMR, it is now possible to gain novel insights into the pathophysiology of IMH and MVO in vivo and evaluate their clinical significance.","tracks":[{"project":"0_colil","denotations":[{"id":"20577881-8633172-54388","span":{"begin":191,"end":193},"obj":"8633172"},{"id":"20577881-1516171-54389","span":{"begin":596,"end":598},"obj":"1516171"},{"id":"20577881-17920380-54390","span":{"begin":747,"end":748},"obj":"17920380"},{"id":"20577881-10556226-54391","span":{"begin":876,"end":878},"obj":"10556226"}],"attributes":[{"subj":"20577881-8633172-54388","pred":"source","obj":"0_colil"},{"subj":"20577881-1516171-54389","pred":"source","obj":"0_colil"},{"subj":"20577881-17920380-54390","pred":"source","obj":"0_colil"},{"subj":"20577881-10556226-54391","pred":"source","obj":"0_colil"}]},{"project":"2_test","denotations":[{"id":"20577881-8633172-29362320","span":{"begin":191,"end":193},"obj":"8633172"},{"id":"20577881-1516171-29362321","span":{"begin":596,"end":598},"obj":"1516171"},{"id":"20577881-17920380-29362322","span":{"begin":747,"end":748},"obj":"17920380"},{"id":"20577881-10556226-29362323","span":{"begin":876,"end":878},"obj":"10556226"}],"attributes":[{"subj":"20577881-8633172-29362320","pred":"source","obj":"2_test"},{"subj":"20577881-1516171-29362321","pred":"source","obj":"2_test"},{"subj":"20577881-17920380-29362322","pred":"source","obj":"2_test"},{"subj":"20577881-10556226-29362323","pred":"source","obj":"2_test"}]},{"project":"TEST0","denotations":[{"id":"20577881-191-197-54388","span":{"begin":191,"end":193},"obj":"[\"8633172\"]"},{"id":"20577881-182-188-54389","span":{"begin":596,"end":598},"obj":"[\"1516171\"]"},{"id":"20577881-146-151-54390","span":{"begin":747,"end":748},"obj":"[\"17920380\"]"},{"id":"20577881-125-131-54391","span":{"begin":876,"end":878},"obj":"[\"10556226\"]"}],"attributes":[{"subj":"20577881-191-197-54388","pred":"source","obj":"TEST0"},{"subj":"20577881-182-188-54389","pred":"source","obj":"TEST0"},{"subj":"20577881-146-151-54390","pred":"source","obj":"TEST0"},{"subj":"20577881-125-131-54391","pred":"source","obj":"TEST0"}]},{"project":"MyTest","denotations":[{"id":"20577881-8633172-29362320","span":{"begin":191,"end":193},"obj":"8633172"},{"id":"20577881-1516171-29362321","span":{"begin":596,"end":598},"obj":"1516171"},{"id":"20577881-17920380-29362322","span":{"begin":747,"end":748},"obj":"17920380"},{"id":"20577881-10556226-29362323","span":{"begin":876,"end":878},"obj":"10556226"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"attributes":[{"subj":"20577881-8633172-29362320","pred":"source","obj":"MyTest"},{"subj":"20577881-1516171-29362321","pred":"source","obj":"MyTest"},{"subj":"20577881-17920380-29362322","pred":"source","obj":"MyTest"},{"subj":"20577881-10556226-29362323","pred":"source","obj":"MyTest"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"0_colil","color":"#a8ec93","default":true},{"id":"2_test","color":"#ec93c2"},{"id":"TEST0","color":"#93dcec"},{"id":"MyTest","color":"#ece193"}]}]}}