PMC:2944667 / 22639-23439 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2944667","sourcedb":"PMC","sourceid":"2944667","source_url":"https://www.ncbi.nlm.nih.gov/pmc/2944667","text":"Biological mechanisms of neuropsychiatric disorders can be studied in clinical populations using multiple lines of inquiry. Structural brain imaging can reveal changes in brain region volume while functional imaging can demonstrate altered functioning of brain regions, both of which may originate in early developmental processes, particularly when found in patients presenting early in the course of illness or young subjects at high risk for psychiatric disorders. More specific mechanisms relevant to stem cell biology may be examined in the post mortem brain as well as genetic analysis of patients. Converging evidence from populations of patients with autism, schizophrenia and affective disorders suggests that stem cell biology is implicated in neuropsychiatric etiology and pathophysiology.","tracks":[]}