PMC:2944646 / 23243-24206 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2944646","sourcedb":"PMC","sourceid":"2944646","source_url":"https://www.ncbi.nlm.nih.gov/pmc/2944646","text":"Piracetam improves measures of mitochondrial function in tgAPP mice. (A) Animals were treated for 14 days with 0.5 g piracetam/kg in 0.9% NaCI solution p.o. once daily for 2 weeks. Control animals received 0.9% NaCI solution alone. All data are modified after Kurz et al. (2010). The MMP was significantly reduced in tgAPP mice. Piracetam treatment normalizes the MMP to non-tgAPP levels. Data are expressed as mean ± SEM (n = 7–8). +p \u003c 0.05 control non-tgAPP vs. control tgAPP, *p \u003c 0.01 piracetam treated tgAPP vs. tgAPP control; Student's unpaired t-test. (B) ATP levels were also significantly impaired in tgAPP mice. In contrast, piracetam treatment increases ATP levels not only in tgAPP animals but also in control animals. Data are expressed as mean ± SEM (n = 7-8). *p \u003c 0.05 control non-tgAPP vs. piracetam treated non-tgAPP; +p \u003c 0.05 control non-tgAPP vs. control tgAPP, *p \u003c 0.01 piracetam treated tgAPP vs. tgAPP control; Student's unpaired t-test.","tracks":[{"project":"TEST0","denotations":[{"id":"20877425-41-49-198953","span":{"begin":273,"end":277},"obj":"[\"20218980\"]"}],"attributes":[{"subj":"20877425-41-49-198953","pred":"source","obj":"TEST0"}]},{"project":"0_colil","denotations":[{"id":"20877425-20218980-198953","span":{"begin":273,"end":277},"obj":"20218980"}],"attributes":[{"subj":"20877425-20218980-198953","pred":"source","obj":"0_colil"}]},{"project":"2_test","denotations":[{"id":"20877425-20218980-38148046","span":{"begin":273,"end":277},"obj":"20218980"}],"attributes":[{"subj":"20877425-20218980-38148046","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"TEST0","color":"#cc93ec","default":true},{"id":"0_colil","color":"#93ecb2"},{"id":"2_test","color":"#ec9893"}]}]}}