PMC:2940453 / 28347-29781
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2940453","sourcedb":"PMC","sourceid":"2940453","source_url":"https://www.ncbi.nlm.nih.gov/pmc/2940453","text":"The third important feature of phase coding becomes evident when we track the activity of a neuron relative to the SMO cycles under a dynamic input condition while also varying the propagation direction of the SMO field. This emulates the condition of recording place in a freely moving animal's hippocampus and computing the phase of spikes relative to ongoing theta LFP oscillations. In similar experiments, the AP phase systematically advances relative to the theta cycles, defined as phase precession (O'Keefe and Recce, 1993; Skaggs et al., 1996; Harris et al., 2002). However, recording theta not only from a single electrode but also from a larger volume around the place cell should reproduce what we found by modeling. Namely, APs should always phase-lock to the intracellular SMO (Harvey et al., 2009), but the direction of phase precession (advancement vs. lagging) will depend on the propagation direction of global SMO/LFP field around the neuron (Nadasdy, 2009). The assumption of SMO field propagation is consistent with the observation of traveling waves in the hippocampus on freely moving rats (Lubenov and Siapas, 2009). The phase-lock between the APs and the intracellular SMO has been confirmed during behavior (Harvey et al., 2009). Combining SMO, LFP, and AP measurements from multiple neurons separated by different distances would elucidate the underlying network dynamics and test the interference principle.","tracks":[{"project":"2_test","denotations":[{"id":"20859525-8353611-38435003","span":{"begin":525,"end":529},"obj":"8353611"},{"id":"20859525-8797016-38435004","span":{"begin":546,"end":550},"obj":"8797016"},{"id":"20859525-12066184-38435005","span":{"begin":567,"end":571},"obj":"12066184"},{"id":"20859525-19829374-38435006","span":{"begin":806,"end":810},"obj":"19829374"},{"id":"20859525-19668700-38435007","span":{"begin":970,"end":974},"obj":"19668700"},{"id":"20859525-19489117-38435008","span":{"begin":1133,"end":1137},"obj":"19489117"},{"id":"20859525-19829374-38435009","span":{"begin":1248,"end":1252},"obj":"19829374"}],"attributes":[{"subj":"20859525-8353611-38435003","pred":"source","obj":"2_test"},{"subj":"20859525-8797016-38435004","pred":"source","obj":"2_test"},{"subj":"20859525-12066184-38435005","pred":"source","obj":"2_test"},{"subj":"20859525-19829374-38435006","pred":"source","obj":"2_test"},{"subj":"20859525-19668700-38435007","pred":"source","obj":"2_test"},{"subj":"20859525-19489117-38435008","pred":"source","obj":"2_test"},{"subj":"20859525-19829374-38435009","pred":"source","obj":"2_test"}]},{"project":"0_colil","denotations":[{"id":"20859525-8353611-532876","span":{"begin":525,"end":529},"obj":"8353611"},{"id":"20859525-8797016-532877","span":{"begin":546,"end":550},"obj":"8797016"},{"id":"20859525-12066184-532878","span":{"begin":567,"end":571},"obj":"12066184"},{"id":"20859525-19829374-532879","span":{"begin":806,"end":810},"obj":"19829374"},{"id":"20859525-19668700-532880","span":{"begin":970,"end":974},"obj":"19668700"},{"id":"20859525-19489117-532881","span":{"begin":1133,"end":1137},"obj":"19489117"},{"id":"20859525-19829374-532882","span":{"begin":1248,"end":1252},"obj":"19829374"}],"attributes":[{"subj":"20859525-8353611-532876","pred":"source","obj":"0_colil"},{"subj":"20859525-8797016-532877","pred":"source","obj":"0_colil"},{"subj":"20859525-12066184-532878","pred":"source","obj":"0_colil"},{"subj":"20859525-19829374-532879","pred":"source","obj":"0_colil"},{"subj":"20859525-19668700-532880","pred":"source","obj":"0_colil"},{"subj":"20859525-19489117-532881","pred":"source","obj":"0_colil"},{"subj":"20859525-19829374-532882","pred":"source","obj":"0_colil"}]},{"project":"TEST0","denotations":[{"id":"20859525-139-147-532876","span":{"begin":525,"end":529},"obj":"[\"8353611\"]"},{"id":"20859525-160-168-532877","span":{"begin":546,"end":550},"obj":"[\"8797016\"]"},{"id":"20859525-181-189-532878","span":{"begin":567,"end":571},"obj":"[\"12066184\"]"},{"id":"20859525-78-86-532879","span":{"begin":806,"end":810},"obj":"[\"19829374\"]"},{"id":"20859525-102-110-532880","span":{"begin":970,"end":974},"obj":"[\"19668700\"]"},{"id":"20859525-156-164-532881","span":{"begin":1133,"end":1137},"obj":"[\"19489117\"]"},{"id":"20859525-108-116-532882","span":{"begin":1248,"end":1252},"obj":"[\"19829374\"]"}],"attributes":[{"subj":"20859525-139-147-532876","pred":"source","obj":"TEST0"},{"subj":"20859525-160-168-532877","pred":"source","obj":"TEST0"},{"subj":"20859525-181-189-532878","pred":"source","obj":"TEST0"},{"subj":"20859525-78-86-532879","pred":"source","obj":"TEST0"},{"subj":"20859525-102-110-532880","pred":"source","obj":"TEST0"},{"subj":"20859525-156-164-532881","pred":"source","obj":"TEST0"},{"subj":"20859525-108-116-532882","pred":"source","obj":"TEST0"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#a0ec93","default":true},{"id":"0_colil","color":"#ec93ba"},{"id":"TEST0","color":"#93d4ec"}]}]}}