PMC:2940021 / 24462-25341 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2940021","sourcedb":"PMC","sourceid":"2940021","source_url":"https://www.ncbi.nlm.nih.gov/pmc/2940021","text":"Recently, we performed muscle imaging in 46 MFM patients (19 desminopathy, 12 myotilinopathy, 11 filaminopathy, 1 αB-crystallinopathy and 3 ZASPopathy patients) and observed two major characteristic patterns of muscle involvement [26]. In desminopathy patients, at the thigh the semitendinosus was the most affected muscle, being more affected than the biceps femoris and semimembranosus muscles. Furthermore, the sartorius and gracilis muscles were often involved earlier and more severely than other thigh muscles. At the lower legs, peroneal muscles were more involved than the tibialis anterior muscle or at least equally as involved. Muscle imaging findings in a patient with a R120G αBC mutation were very similar to those in desminopathy patients. The most frequently involved muscles were the gluteus maximus, semitendinosus, sartorius, gracilis and the peroneal muscles.","tracks":[{"project":"0_colil","denotations":[{"id":"20422195-18765652-60969","span":{"begin":231,"end":233},"obj":"18765652"}],"attributes":[{"subj":"20422195-18765652-60969","pred":"source","obj":"0_colil"}]},{"project":"2_test","denotations":[{"id":"20422195-18765652-29368053","span":{"begin":231,"end":233},"obj":"18765652"}],"attributes":[{"subj":"20422195-18765652-29368053","pred":"source","obj":"2_test"}]},{"project":"TEST0","denotations":[{"id":"20422195-231-237-60969","span":{"begin":231,"end":233},"obj":"[\"18765652\"]"}],"attributes":[{"subj":"20422195-231-237-60969","pred":"source","obj":"TEST0"}]},{"project":"MyTest","denotations":[{"id":"20422195-18765652-29368053","span":{"begin":231,"end":233},"obj":"18765652"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"attributes":[{"subj":"20422195-18765652-29368053","pred":"source","obj":"MyTest"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"0_colil","color":"#ecc293","default":true},{"id":"2_test","color":"#a893ec"},{"id":"TEST0","color":"#97ec93"},{"id":"MyTest","color":"#ec93b1"}]}]}}