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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2940017","sourcedb":"PMC","sourceid":"2940017","source_url":"https://www.ncbi.nlm.nih.gov/pmc/2940017","text":"In order to verify that the different contrast protocols did not significantly influence the perfusion parameters, they were compared for the high-grade glioma patients, as high-grade gliomas represent the largest group in our series. Furthermore, all perfusion parameters in this histopathological subgroup were found to be significantly higher than normal parenchyma. The potential heterogeneity due to different contrast material protocols was assessed through the comparison of all perfusion parameters (Table 1). No significant difference was found between the two subgroups. Therefore they were evaluated as one entity for further statistical analysis.\nTable 1 Comparison of different contrast material protocols: Mann-Whitney U-test showed no significant difference between the two subgroups (values expressed as median and interquartile range)\nContrast material protocol 1 (n = 19) Contrast material protocol 2 (n = 10) p\nK trans (ml/100 ml/min) 5.80 4.04 \u003e0.05\n(4.43–9.45) (3.27–9.99)\nCBV (ml/100 ml) 5.37 5.58 \u003e0.05\n(4.36–6.74) (4.71–7.55)\nCBF (ml/min) 75.69 110.00 \u003e0.05\n(62.12–108.73) (84.99–132.18)","divisions":[{"label":"label","span":{"begin":659,"end":666}},{"label":"caption","span":{"begin":667,"end":851}},{"label":"p","span":{"begin":667,"end":851}},{"label":"tr","span":{"begin":852,"end":930}},{"label":"th","span":{"begin":852,"end":889}},{"label":"th","span":{"begin":890,"end":927}},{"label":"th","span":{"begin":928,"end":930}},{"label":"tr","span":{"begin":931,"end":970}},{"label":"td","span":{"begin":931,"end":955}},{"label":"td","span":{"begin":955,"end":959}},{"label":"td","span":{"begin":960,"end":964}},{"label":"td","span":{"begin":965,"end":970}},{"label":"tr","span":{"begin":971,"end":994}},{"label":"td","span":{"begin":971,"end":982}},{"label":"td","span":{"begin":983,"end":994}},{"label":"tr","span":{"begin":995,"end":1026}},{"label":"td","span":{"begin":995,"end":1010}},{"label":"td","span":{"begin":1011,"end":1015}},{"label":"td","span":{"begin":1016,"end":1020}},{"label":"td","span":{"begin":1021,"end":1026}},{"label":"tr","span":{"begin":1027,"end":1050}},{"label":"td","span":{"begin":1027,"end":1038}},{"label":"td","span":{"begin":1039,"end":1050}},{"label":"tr","span":{"begin":1051,"end":1082}},{"label":"td","span":{"begin":1051,"end":1063}},{"label":"td","span":{"begin":1064,"end":1069}},{"label":"td","span":{"begin":1070,"end":1076}},{"label":"td","span":{"begin":1077,"end":1082}},{"label":"td","span":{"begin":1083,"end":1097}}],"tracks":[]}