PMC:2940017 / 14406-15660 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2940017","sourcedb":"PMC","sourceid":"2940017","source_url":"https://www.ncbi.nlm.nih.gov/pmc/2940017","text":"In this study, our objective was to quantify the absolute PCT parameters of intracerebral tumours. We report one of the largest series concerning the application and efficacy of PCT in the preoperative histopathological grouping of cerebral intra-axial tumours. By applying a CT perfusion method and based on the absolute perfusion parameters, we differentiated cerebral lymphomas from high-grade gliomas (Figs. 4, 5).\nFig. 4 A 58-year-old man with histopathological diagnosis of glioblastoma multiforme WHO IV. Axial contrast-enhanced MIP reconstruction image (a) shows a contrast-enhanced mass, which demonstrates intensely elevated blood flow (b) and volume (c) as well as strongly increased regional K trans (d) in comparison with the normal cortical and subcortical cerebral parenchyma\nFig. 5 A 72-year-old woman with histopathological diagnosis of primary cerebral lymphoma. In comparison with the contralateral normal cerebral parenchyma, the lesion depicted in the right lentiform nucleus demonstrates the typical perfusion characteristics of lymphoma: enhancement (a), no significant increase in CBF (b) or CBV values (c), though intensely increased regional permeability (K Trans, d), indicating a massive disturbance of the blood-brain barrier","divisions":[{"label":"figure","span":{"begin":419,"end":790}},{"label":"label","span":{"begin":419,"end":425}},{"label":"caption","span":{"begin":426,"end":790}},{"label":"p","span":{"begin":426,"end":790}},{"label":"label","span":{"begin":791,"end":797}}],"tracks":[]}