PMC:2940017 / 11546-13132 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2940017","sourcedb":"PMC","sourceid":"2940017","source_url":"https://www.ncbi.nlm.nih.gov/pmc/2940017","text":"Comparison of perfusion parameters between affected and normal cerebral parenchyma\nThe mean values for K Trans, CBV and CBF values for the study subgroups and the comparisons with the control healthy parenchyma are summarised in Table 3. No significant difference in the perfusion parameters was found between areas of low-grade gliomas and normal cerebral parenchyma (p \u003e 0.05 for all analysed perfusion parameters). High-grade gliomas, on the other hand, demonstrated significantly higher values of all perfusion parameters compared with normal cerebral parenchyma (p \u003c 0.0001 for KTrans, p \u003c 0.0001 for CBV and p = 0.0002 for CBF). Lymphomas displayed significantly increased mean permeability values compared with unaffected cerebral parenchyma (p = 0.0078 for K Trans), whereas no significant difference was noted between the mean CBV and CBF values (p = 0.55 for CBV, p = 0.25 for CBF).\nTable 3 Comparison of perfusion parameters between affected and normal cerebral parenchyma. Values are expressed as mean ± SD\nHistopathological K Trans p a CBV p a CBF p a\nsubgroup (p) (ml/100 ml/min) (ml/100 ml) (ml/100 ml/min)\nLesion Control Lesion Control Lesion Control\nLow-grade gliomas (4) 3.73 ± 5.35 1.66 ± 1.79 0.25 3.28 ± 0.46 2.96 ± 0.42 0.38 62.28 ± 16.91 65.80 ± 5.50 0.88\nHigh-grade gliomas (31) 6.58 ± 3.68 0.86 ± 0.79 \u003c0.0001 6.03 ± 2.18 3.22 ± 0.42 \u003c0.0001 97.63 ± 41.17 64.45 ± 7.84 0.0002\nLymphomas (8) 11.96 ± 10.66 1.31 ± 1.79 0.0078 3.79 ± 1.95 3.14 ± 0.42 0.55 82.79 ± 40.03 64.87 ± 9.61 0.25\na p compared with healthy parenchyma values (control) using Wilcoxon test","divisions":[{"label":"title","span":{"begin":0,"end":82}},{"label":"label","span":{"begin":893,"end":900}},{"label":"caption","span":{"begin":901,"end":1018}},{"label":"p","span":{"begin":901,"end":1018}},{"label":"table","span":{"begin":1019,"end":1512}},{"label":"tr","span":{"begin":1019,"end":1068}},{"label":"th","span":{"begin":1019,"end":1036}},{"label":"th","span":{"begin":1037,"end":1045}},{"label":"th","span":{"begin":1046,"end":1050}},{"label":"th","span":{"begin":1051,"end":1054}},{"label":"th","span":{"begin":1055,"end":1059}},{"label":"th","span":{"begin":1060,"end":1063}},{"label":"th","span":{"begin":1064,"end":1068}},{"label":"tr","span":{"begin":1069,"end":1125}},{"label":"th","span":{"begin":1069,"end":1081}},{"label":"th","span":{"begin":1082,"end":1097}},{"label":"th","span":{"begin":1098,"end":1109}},{"label":"th","span":{"begin":1110,"end":1125}},{"label":"tr","span":{"begin":1126,"end":1170}},{"label":"th","span":{"begin":1126,"end":1132}},{"label":"th","span":{"begin":1133,"end":1140}},{"label":"th","span":{"begin":1141,"end":1147}},{"label":"th","span":{"begin":1148,"end":1155}},{"label":"th","span":{"begin":1156,"end":1162}},{"label":"th","span":{"begin":1163,"end":1170}},{"label":"tr","span":{"begin":1171,"end":1282}},{"label":"td","span":{"begin":1171,"end":1192}},{"label":"td","span":{"begin":1193,"end":1204}},{"label":"td","span":{"begin":1205,"end":1216}},{"label":"td","span":{"begin":1217,"end":1221}},{"label":"td","span":{"begin":1222,"end":1233}},{"label":"td","span":{"begin":1234,"end":1245}},{"label":"td","span":{"begin":1246,"end":1250}},{"label":"td","span":{"begin":1251,"end":1264}},{"label":"td","span":{"begin":1265,"end":1277}},{"label":"td","span":{"begin":1278,"end":1282}},{"label":"tr","span":{"begin":1283,"end":1404}},{"label":"td","span":{"begin":1283,"end":1306}},{"label":"td","span":{"begin":1307,"end":1318}},{"label":"td","span":{"begin":1319,"end":1330}},{"label":"td","span":{"begin":1331,"end":1338}},{"label":"td","span":{"begin":1339,"end":1350}},{"label":"td","span":{"begin":1351,"end":1362}},{"label":"td","span":{"begin":1363,"end":1370}},{"label":"td","span":{"begin":1371,"end":1384}},{"label":"td","span":{"begin":1385,"end":1397}},{"label":"td","span":{"begin":1398,"end":1404}},{"label":"tr","span":{"begin":1405,"end":1512}},{"label":"td","span":{"begin":1405,"end":1418}},{"label":"td","span":{"begin":1419,"end":1432}},{"label":"td","span":{"begin":1433,"end":1444}},{"label":"td","span":{"begin":1445,"end":1451}},{"label":"td","span":{"begin":1452,"end":1463}},{"label":"td","span":{"begin":1464,"end":1475}},{"label":"td","span":{"begin":1476,"end":1480}},{"label":"td","span":{"begin":1481,"end":1494}},{"label":"td","span":{"begin":1495,"end":1507}},{"label":"td","span":{"begin":1508,"end":1512}}],"tracks":[]}