PMC:2918338 / 2940-3623 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2918338","sourcedb":"PMC","sourceid":"2918338","source_url":"https://www.ncbi.nlm.nih.gov/pmc/2918338","text":"No adverse effects were seen in the tretinoin treated group. However, as many as 135 patients in the treatment group died during study period which was statistically significant. In view of this, Central Human Rights Committee asked investigators to stop intervention and continue follow-up of the patients only, till the completion of the study period. Vigorous efforts were made to analyze the cause of death such as quantity of the drug used by the patients. Vascular disorders were noted as the leading cause of death. Small-cell lung cancer, respiratory, cardiovascular and mediastinal diseases were the other conditions responsible for death of patients in the tretinoin group.","tracks":[]}