
PMC:2889865 / 871-1179
Annnotations
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T679 | 0-3 | DT | denotes | The |
T680 | 4-12 | NN | denotes | cytokine |
T681 | 13-20 | NN | denotes | profile |
T682 | 21-29 | VB | denotes | revealed |
T683 | 30-32 | DT | denotes | an |
T684 | 33-46 | NN | denotes | up-regulation |
T685 | 47-49 | IN | denotes | of |
T686 | 50-53 | DT | denotes | the |
T687 | 54-63 | NN | denotes | chemokine |
T688 | 64-69 | NN | denotes | CXCL8 |
T689 | 70-73 | CC | denotes | and |
T690 | 74-77 | DT | denotes | the |
T691 | 78-94 | JJ | denotes | pro-inflammatory |
T692 | 95-104 | NN | denotes | cytokines |
T693 | 105-108 | NN | denotes | TNF |
T694 | 108-109 | -COMMA- | denotes | , |
T695 | 110-114 | NN | denotes | IL-2 |
T696 | 115-118 | CC | denotes | and |
T697 | 119-123 | NN | denotes | IL-6 |
T698 | 124-133 | VB | denotes | following |
T699 | 134-143 | NN | denotes | treatment |
T700 | 144-148 | IN | denotes | with |
T701 | 149-153 | CC | denotes | both |
T702 | 154-157 | NN | denotes | PMA |
T703 | 158-161 | CC | denotes | and |
T704 | 162-164 | NN | denotes | HK |
T705 | 165-167 | FW | denotes | E. |
T706 | 168-172 | FW | denotes | coli |
T707 | 172-173 | -COMMA- | denotes | , |
T708 | 174-179 | IN | denotes | while |
T709 | 180-183 | DT | denotes | the |
T710 | 184-190 | NN | denotes | levels |
T711 | 191-193 | IN | denotes | of |
T712 | 194-197 | DT | denotes | the |
T713 | 198-215 | JJ | denotes | anti-inflammatory |
T714 | 216-224 | NN | denotes | cytokine |
T715 | 225-230 | NN | denotes | IL-10 |
T716 | 231-235 | VB | denotes | were |
T717 | 236-239 | RB | denotes | not |
T718 | 240-248 | VB | denotes | affected |
T719 | 249-251 | IN | denotes | by |
T720 | 252-255 | NN | denotes | PMA |
T721 | 256-259 | CC | denotes | but |
T722 | 260-264 | VB | denotes | were |
T723 | 265-278 | RB | denotes | significantly |
T724 | 279-293 | VB | denotes | down-regulated |
T725 | 294-296 | IN | denotes | by |
T726 | 297-299 | NNP | denotes | HK |
T727 | 300-302 | NNP | denotes | E. |
T728 | 303-307 | FW | denotes | coli |
R563 | T681 | T679 | arg1Of | profile,The |
R564 | T681 | T680 | arg1Of | profile,cytokine |
R565 | T681 | T682 | arg1Of | profile,revealed |
R566 | T682 | T698 | arg1Of | revealed,following |
R567 | T682 | T707 | arg1Of | revealed,"," |
R568 | T682 | T708 | arg1Of | revealed,while |
R569 | T684 | T683 | arg1Of | up-regulation,an |
R570 | T684 | T685 | arg1Of | up-regulation,of |
R571 | T684 | T689 | arg1Of | up-regulation,and |
R572 | T688 | T685 | arg2Of | CXCL8,of |
R573 | T688 | T686 | arg1Of | CXCL8,the |
R574 | T688 | T687 | arg1Of | CXCL8,chemokine |
R575 | T689 | T682 | arg2Of | and,revealed |
R576 | T692 | T690 | arg1Of | cytokines,the |
R577 | T692 | T691 | arg1Of | cytokines,pro-inflammatory |
R578 | T693 | T694 | arg1Of | TNF,"," |
R579 | T694 | T696 | arg1Of | ",",and |
R580 | T695 | T694 | arg2Of | IL-2,"," |
R581 | T696 | T689 | arg2Of | and,and |
R582 | T696 | T692 | arg1Of | and,cytokines |
R583 | T697 | T696 | arg2Of | IL-6,and |
R584 | T699 | T698 | arg2Of | treatment,following |
R585 | T699 | T700 | arg1Of | treatment,with |
R586 | T702 | T703 | arg1Of | PMA,and |
R587 | T703 | T700 | arg2Of | and,with |
R588 | T703 | T701 | arg1Of | and,both |
R589 | T703 | T706 | arg1Of | and,coli |
R590 | T704 | T703 | arg2Of | HK,and |
R591 | T706 | T705 | arg1Of | coli,E. |
R592 | T710 | T709 | arg1Of | levels,the |
R593 | T710 | T711 | arg1Of | levels,of |
R594 | T710 | T716 | arg1Of | levels,were |
R595 | T710 | T718 | arg2Of | levels,affected |
R596 | T710 | T722 | arg1Of | levels,were |
R597 | T710 | T724 | arg2Of | levels,down-regulated |
R598 | T715 | T711 | arg2Of | IL-10,of |
R599 | T715 | T712 | arg1Of | IL-10,the |
R600 | T715 | T713 | arg1Of | IL-10,anti-inflammatory |
R601 | T715 | T714 | arg1Of | IL-10,cytokine |
R602 | T718 | T716 | arg2Of | affected,were |
R603 | T718 | T717 | arg1Of | affected,not |
R604 | T718 | T721 | arg1Of | affected,but |
R605 | T720 | T718 | arg1Of | PMA,affected |
R606 | T720 | T719 | arg2Of | PMA,by |
R607 | T721 | T708 | arg2Of | but,while |
R608 | T724 | T721 | arg2Of | down-regulated,but |
R609 | T724 | T722 | arg2Of | down-regulated,were |
R610 | T724 | T723 | arg1Of | down-regulated,significantly |
R611 | T727 | T724 | arg1Of | E.,down-regulated |
R612 | T727 | T725 | arg2Of | E.,by |
R613 | T727 | T726 | arg1Of | E.,HK |
R614 | T727 | T728 | arg1Of | E.,coli |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T283 | 0-3 | DT | denotes | The |
T284 | 4-12 | NN | denotes | cytokine |
T285 | 13-20 | NN | denotes | profile |
T286 | 21-29 | VBD | denotes | revealed |
T287 | 30-32 | DT | denotes | an |
T288 | 33-46 | NN | denotes | up-regulation |
T289 | 47-49 | IN | denotes | of |
T290 | 50-53 | DT | denotes | the |
T291 | 54-63 | NN | denotes | chemokine |
T292 | 64-69 | NNP | denotes | CXCL8 |
T293 | 70-73 | CC | denotes | and |
T294 | 74-77 | DT | denotes | the |
T295 | 78-94 | JJ | denotes | pro-inflammatory |
T296 | 95-104 | NNS | denotes | cytokines |
T297 | 105-108 | NNP | denotes | TNF |
T298 | 108-109 | , | denotes | , |
T299 | 110-114 | NNP | denotes | IL-2 |
T300 | 115-118 | CC | denotes | and |
T301 | 119-123 | NNP | denotes | IL-6 |
T302 | 124-133 | VBG | denotes | following |
T303 | 134-143 | NN | denotes | treatment |
T304 | 144-148 | IN | denotes | with |
T305 | 149-153 | DT | denotes | both |
T306 | 154-157 | NNP | denotes | PMA |
T307 | 158-161 | CC | denotes | and |
T308 | 162-164 | NNP | denotes | HK |
T309 | 165-167 | NNP | denotes | E. |
T310 | 168-172 | NNS | denotes | coli |
T311 | 172-173 | , | denotes | , |
T312 | 174-179 | IN | denotes | while |
T313 | 180-183 | DT | denotes | the |
T314 | 184-190 | NNS | denotes | levels |
T315 | 191-193 | IN | denotes | of |
T316 | 194-197 | DT | denotes | the |
T317 | 198-215 | JJ | denotes | anti-inflammatory |
T318 | 216-224 | NN | denotes | cytokine |
T319 | 225-230 | NN | denotes | IL-10 |
T320 | 231-235 | VBD | denotes | were |
T321 | 236-239 | RB | denotes | not |
T322 | 240-248 | VBN | denotes | affected |
T323 | 249-251 | IN | denotes | by |
T324 | 252-255 | NNP | denotes | PMA |
T325 | 256-259 | CC | denotes | but |
T326 | 260-264 | VBD | denotes | were |
T327 | 265-278 | RB | denotes | significantly |
T328 | 279-293 | VBN | denotes | down-regulated |
T329 | 294-296 | IN | denotes | by |
T330 | 297-299 | NNP | denotes | HK |
T331 | 300-302 | NNP | denotes | E. |
T332 | 303-307 | NNS | denotes | coli |
T333 | 307-308 | . | denotes | . |
R173 | T283 | T285 | det | The,profile |
R174 | T284 | T285 | compound | cytokine,profile |
R175 | T285 | T286 | nsubj | profile,revealed |
R176 | T286 | T286 | ROOT | revealed,revealed |
R177 | T287 | T288 | det | an,up-regulation |
R178 | T288 | T286 | dobj | up-regulation,revealed |
R179 | T289 | T288 | prep | of,up-regulation |
R180 | T290 | T292 | det | the,CXCL8 |
R181 | T291 | T292 | compound | chemokine,CXCL8 |
R182 | T292 | T289 | pobj | CXCL8,of |
R183 | T293 | T292 | cc | and,CXCL8 |
R184 | T294 | T296 | det | the,cytokines |
R185 | T295 | T296 | nsubj | pro-inflammatory,cytokines |
R186 | T296 | T292 | conj | cytokines,CXCL8 |
R187 | T297 | T296 | conj | TNF,cytokines |
R188 | T298 | T297 | punct | ",",TNF |
R189 | T299 | T297 | conj | IL-2,TNF |
R190 | T300 | T299 | cc | and,IL-2 |
R191 | T301 | T299 | conj | IL-6,IL-2 |
R192 | T302 | T286 | prep | following,revealed |
R193 | T303 | T302 | pobj | treatment,following |
R194 | T304 | T303 | prep | with,treatment |
R195 | T305 | T306 | det | both,PMA |
R196 | T306 | T304 | pobj | PMA,with |
R197 | T307 | T306 | cc | and,PMA |
R198 | T308 | T310 | compound | HK,coli |
R199 | T309 | T310 | compound | E.,coli |
R200 | T310 | T306 | conj | coli,PMA |
R201 | T311 | T286 | punct | ",",revealed |
R202 | T312 | T322 | mark | while,affected |
R203 | T313 | T314 | det | the,levels |
R204 | T314 | T322 | nsubjpass | levels,affected |
R205 | T315 | T314 | prep | of,levels |
R206 | T316 | T319 | det | the,IL-10 |
R207 | T317 | T319 | amod | anti-inflammatory,IL-10 |
R208 | T318 | T319 | compound | cytokine,IL-10 |
R209 | T319 | T315 | pobj | IL-10,of |
R210 | T320 | T322 | auxpass | were,affected |
R211 | T321 | T322 | neg | not,affected |
R212 | T322 | T286 | advcl | affected,revealed |
R213 | T323 | T322 | agent | by,affected |
R214 | T324 | T323 | pobj | PMA,by |
R215 | T325 | T322 | cc | but,affected |
R216 | T326 | T328 | auxpass | were,down-regulated |
R217 | T327 | T328 | advmod | significantly,down-regulated |
R218 | T328 | T322 | conj | down-regulated,affected |
R219 | T329 | T328 | agent | by,down-regulated |
R220 | T330 | T332 | compound | HK,coli |
R221 | T331 | T332 | compound | E.,coli |
R222 | T332 | T329 | pobj | coli,by |
R223 | T333 | T286 | punct | .,revealed |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T973 | 36-46 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
T987 | 33-63 | http://purl.obolibrary.org/obo/GO_0032722 | denotes | up-regulation of the chemokine |
GO-MF
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1007 | 119-123 | http://purl.obolibrary.org/obo/GO_0005138 | denotes | IL-6 |
T1011 | 110-114 | http://purl.obolibrary.org/obo/GO_0005134 | denotes | IL-2 |
T1012 | 225-230 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T126 | 0-308 | Sentence | denotes | The cytokine profile revealed an up-regulation of the chemokine CXCL8 and the pro-inflammatory cytokines TNF, IL-2 and IL-6 following treatment with both PMA and HK E. coli, while the levels of the anti-inflammatory cytokine IL-10 were not affected by PMA but were significantly down-regulated by HK E. coli. |
T9 | 0-308 | Sentence | denotes | The cytokine profile revealed an up-regulation of the chemokine CXCL8 and the pro-inflammatory cytokines TNF, IL-2 and IL-6 following treatment with both PMA and HK E. coli, while the levels of the anti-inflammatory cytokine IL-10 were not affected by PMA but were significantly down-regulated by HK E. coli. |
events-check-again
Id | Subject | Object | Predicate | Lexical cue | Negation |
---|---|---|---|---|---|
T1220 | 33-46 | Positive_regulation | denotes | up-regulation | |
T1221 | 33-46 | Positive_regulation | denotes | up-regulation | |
T1222 | 33-46 | Positive_regulation | denotes | up-regulation | |
T1223 | 64-69 | Protein | denotes | CXCL8 | |
T1224 | 110-114 | Protein | denotes | IL-2 | |
T1225 | 119-123 | Protein | denotes | IL-6 | |
T1226 | 225-230 | Protein | denotes | IL-10 | |
T1227 | 240-248 | Regulation | denotes | affected | true |
T1228 | 279-293 | Negative_regulation | denotes | down-regulated | |
R881 | T1223 | T1222 | themeOf | CXCL8,up-regulation | |
R882 | T1224 | T1220 | themeOf | IL-2,up-regulation | |
R883 | T1225 | T1221 | themeOf | IL-6,up-regulation | |
R884 | T1226 | T1227 | themeOf | IL-10,affected | |
R885 | T1226 | T1228 | themeOf | IL-10,down-regulated |
bionlp-st-ge-2016-reference-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1278 | 64-69 | Protein | denotes | CXCL8 |
T1279 | 95-114 | Protein | denotes | cytokines TNF, IL-2 |
T1280 | 119-123 | Protein | denotes | IL-6 |
T1281 | 33-46 | Positive_regulation | denotes | up-regulation |
T1282 | 33-46 | Positive_regulation | denotes | up-regulation |
T1283 | 33-46 | Positive_regulation | denotes | up-regulation |
T1284 | 240-248 | Regulation | denotes | affected |
T1285 | 240-248 | Regulation | denotes | affected |
T1286 | 240-248 | Regulation | denotes | affected |
T1287 | 240-248 | Regulation | denotes | affected |
R910 | T1278 | T1281 | themeOf | CXCL8,up-regulation |
R911 | T1279 | T1282 | themeOf | "cytokines TNF, IL-2",up-regulation |
R912 | T1280 | T1283 | themeOf | IL-6,up-regulation |
R913 | T1280 | T1284 | themeOf | IL-6,affected |
R914 | T1281 | T1285 | themeOf | up-regulation,affected |
R915 | T1282 | T1286 | themeOf | up-regulation,affected |
R916 | T1283 | T1287 | themeOf | up-regulation,affected |
bionlp-st-ge-2016-reference
Id | Subject | Object | Predicate | Lexical cue | Negation |
---|---|---|---|---|---|
T87 | 33-46 | Positive_regulation | denotes | up-regulation | |
T88 | 33-46 | Positive_regulation | denotes | up-regulation | |
T89 | 33-46 | Positive_regulation | denotes | up-regulation | |
T90 | 64-69 | Protein | denotes | CXCL8 | |
T91 | 110-114 | Protein | denotes | IL-2 | |
T92 | 119-123 | Protein | denotes | IL-6 | |
T93 | 225-230 | Protein | denotes | IL-10 | |
T94 | 240-248 | Regulation | denotes | affected | true |
T95 | 279-293 | Negative_regulation | denotes | down-regulated | |
R49 | T90 | T89 | themeOf | CXCL8,up-regulation | |
R50 | T91 | T87 | themeOf | IL-2,up-regulation | |
R51 | T92 | T88 | themeOf | IL-6,up-regulation | |
R52 | T93 | T94 | themeOf | IL-10,affected | |
R53 | T93 | T95 | themeOf | IL-10,down-regulated |
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T934 | 64-69 | P10145 | denotes | CXCL8 |
T935 | 105-108 | P01375 | denotes | TNF |
T936 | 110-114 | P60568 | denotes | IL-2 |
T937 | 119-123 | P05231 | denotes | IL-6 |
T938 | 225-230 | P22301 | denotes | IL-10 |
test2
Id | Subject | Object | Predicate | Lexical cue | Negation |
---|---|---|---|---|---|
T48 | 33-46 | Positive_regulation | denotes | up-regulation | true |
T49 | 64-69 | Protein | denotes | CXCL8 | |
T50 | 110-114 | Protein | denotes | IL-2 | |
T51 | 119-123 | Protein | denotes | IL-6 | |
T52 | 124-133 | Positive_regulation | denotes | following | |
T53 | 225-230 | Protein | denotes | IL-10 | |
T54 | 240-248 | Regulation | denotes | affected | |
T55 | 279-293 | Negative_regulation | denotes | down-regulated | |
R26 | T49 | T48 | themeOf | CXCL8,up-regulation | |
R27 | T50 | T48 | themeOf | IL-2,up-regulation | |
R28 | T51 | T48 | themeOf | IL-6,up-regulation | |
R29 | T53 | T54 | themeOf | IL-10,affected | |
R30 | T53 | T55 | themeOf | IL-10,down-regulated |