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PMC:2889865 / 80-601 JSONTXT

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pmc-enju-pas

Id Subject Object Predicate Lexical cue
T549 0-10 NN denotes Background
T550 11-20 NN denotes Activator
T551 21-28 NN denotes protein
T552 29-30 -LRB- denotes (
T553 30-32 NN denotes AP
T554 32-33 -RRB- denotes )
T555 33-35 CD denotes -1
T556 36-39 CC denotes and
T557 40-47 JJ denotes nuclear
T558 48-54 NN denotes factor
T559 55-56 -LRB- denotes (
T560 56-58 NN denotes NF
T561 58-59 -RRB- denotes )
T562 59-62 NN denotes -κB
T563 63-70 RB denotes largely
T564 71-78 VB denotes control
T565 79-85 NN denotes T-cell
T566 86-96 NN denotes activation
T567 96-97 -COMMA- denotes ,
T568 98-107 VB denotes following
T569 108-115 NN denotes binding
T570 116-118 IN denotes of
T571 119-126 JJ denotes foreign
T572 127-135 NN denotes antigens
T573 136-138 TO denotes to
T574 139-142 DT denotes the
T575 143-149 NN denotes T-cell
T576 150-158 NN denotes receptor
T577 159-166 VB denotes leading
T578 167-169 TO denotes to
T579 170-178 NN denotes cytokine
T580 179-188 NN denotes secretion
T581 190-198 JJ denotes Elevated
T582 199-205 NN denotes levels
T583 206-208 IN denotes of
T584 209-225 JJ denotes pro-inflammatory
T585 226-235 NN denotes cytokines
T586 236-239 CC denotes and
T587 240-250 NN denotes chemokines
T588 251-255 JJ denotes such
T589 256-258 IN denotes as
T590 259-262 NN denotes TNF
T591 262-263 -COMMA- denotes ,
T592 264-268 NN denotes IL-6
T593 269-272 CC denotes and
T594 273-278 NN denotes CXCL8
T595 279-282 VB denotes are
T596 283-293 VB denotes associated
T597 294-298 IN denotes with
T598 299-306 JJ denotes several
T599 307-312 JJ denotes human
T600 313-321 NN denotes diseases
T601 322-331 VB denotes including
T602 332-338 JJ denotes cystic
T603 339-347 NN denotes fibrosis
T604 347-348 -COMMA- denotes ,
T605 349-358 JJ denotes pulmonary
T606 359-367 NN denotes fibrosis
T607 368-371 CC denotes and
T608 372-376 NN denotes AIDS
T609 378-381 DT denotes The
T610 382-385 NN denotes aim
T611 386-388 IN denotes of
T612 389-393 DT denotes this
T613 394-399 NN denotes study
T614 400-403 VB denotes was
T615 404-406 TO denotes to
T616 407-418 VB denotes investigate
T617 419-422 DT denotes the
T618 423-427 NN denotes role
T619 428-430 IN denotes of
T620 431-434 DT denotes the
T621 435-448 NN denotes transcription
T622 449-456 NN denotes factors
T623 456-457 -COMMA- denotes ,
T624 458-462 NN denotes AP-1
T625 463-466 CC denotes and
T626 467-472 NN denotes NF-κB
T627 472-473 -COMMA- denotes ,
T628 474-476 IN denotes in
T629 477-481 NN denotes IL-6
T630 482-485 CC denotes and
T631 486-491 NN denotes CXCL8
T632 492-502 NN denotes regulation
T633 503-505 IN denotes in
T634 506-512 NN denotes Jurkat
T635 513-520 NN denotes T-cells
R437 T551 T550 arg1Of protein,Activator
R438 T551 T552 arg1Of protein,(
R439 T551 T555 arg1Of protein,-1
R440 T551 T556 arg1Of protein,and
R441 T553 T552 arg2Of AP,(
R442 T554 T552 arg3Of ),(
R443 T556 T564 arg1Of and,control
R444 T560 T559 arg2Of NF,(
R445 T561 T559 arg3Of ),(
R446 T562 T556 arg2Of -κB,and
R447 T562 T557 arg1Of -κB,nuclear
R448 T562 T558 arg1Of -κB,factor
R449 T562 T559 arg1Of -κB,(
R450 T564 T563 arg1Of control,largely
R451 T564 T567 arg1Of control,","
R452 T564 T568 arg1Of control,following
R453 T566 T564 arg2Of activation,control
R454 T566 T565 arg1Of activation,T-cell
R455 T569 T568 arg2Of binding,following
R456 T569 T570 arg1Of binding,of
R457 T569 T573 arg1Of binding,to
R458 T572 T570 arg2Of antigens,of
R459 T572 T571 arg1Of antigens,foreign
R460 T576 T573 arg2Of receptor,to
R461 T576 T574 arg1Of receptor,the
R462 T576 T575 arg1Of receptor,T-cell
R463 T576 T577 arg1Of receptor,leading
R464 T577 T578 arg1Of leading,to
R465 T580 T578 arg2Of secretion,to
R466 T580 T579 arg1Of secretion,cytokine
R467 T582 T581 arg1Of levels,Elevated
R468 T582 T583 arg1Of levels,of
R469 T582 T595 arg1Of levels,are
R470 T582 T596 arg2Of levels,associated
R471 T585 T586 arg1Of cytokines,and
R472 T586 T583 arg2Of and,of
R473 T586 T584 arg1Of and,pro-inflammatory
R474 T586 T589 arg1Of and,as
R475 T587 T586 arg2Of chemokines,and
R476 T589 T588 arg1Of as,such
R477 T590 T591 arg1Of TNF,","
R478 T591 T593 arg1Of ",",and
R479 T592 T591 arg2Of IL-6,","
R480 T593 T589 arg2Of and,as
R481 T594 T593 arg2Of CXCL8,and
R482 T596 T595 arg2Of associated,are
R483 T596 T597 arg1Of associated,with
R484 T600 T597 arg2Of diseases,with
R485 T600 T598 arg1Of diseases,several
R486 T600 T599 arg1Of diseases,human
R487 T600 T601 arg1Of diseases,including
R488 T603 T602 arg1Of fibrosis,cystic
R489 T603 T604 arg1Of fibrosis,","
R490 T604 T607 arg1Of ",",and
R491 T606 T604 arg2Of fibrosis,","
R492 T606 T605 arg1Of fibrosis,pulmonary
R493 T607 T601 arg2Of and,including
R494 T608 T607 arg2Of AIDS,and
R495 T610 T609 arg1Of aim,The
R496 T610 T611 arg1Of aim,of
R497 T610 T614 arg1Of aim,was
R498 T613 T611 arg2Of study,of
R499 T613 T612 arg1Of study,this
R500 T616 T614 arg2Of investigate,was
R501 T616 T615 arg1Of investigate,to
R502 T618 T616 arg2Of role,investigate
R503 T618 T617 arg1Of role,the
R504 T618 T619 arg1Of role,of
R505 T618 T627 arg1Of role,","
R506 T618 T628 arg1Of role,in
R507 T622 T619 arg2Of factors,of
R508 T622 T620 arg1Of factors,the
R509 T622 T621 arg1Of factors,transcription
R510 T622 T623 arg1Of factors,","
R511 T624 T625 arg1Of AP-1,and
R512 T625 T623 arg2Of and,","
R513 T626 T625 arg2Of NF-κB,and
R514 T629 T630 arg1Of IL-6,and
R515 T631 T630 arg2Of CXCL8,and
R516 T632 T628 arg2Of regulation,in
R517 T632 T629 arg1Of regulation,IL-6
R518 T632 T631 arg1Of regulation,CXCL8
R519 T632 T633 arg1Of regulation,in
R520 T635 T633 arg2Of T-cells,in
R521 T635 T634 arg1Of T-cells,Jurkat

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T166 96-97 , denotes ,
T167 98-107 VBG denotes following
T168 108-115 JJ denotes binding
T169 116-118 IN denotes of
T170 119-126 JJ denotes foreign
T171 127-135 NNS denotes antigens
T172 136-138 TO denotes to
T173 139-142 DT denotes the
T174 143-149 NN denotes T-cell
T175 150-158 NN denotes receptor
T176 159-166 VBG denotes leading
T177 167-169 TO denotes to
T178 170-178 VB denotes cytokine
T179 179-188 NN denotes secretion
T180 188-189 . denotes .
T181 190-198 JJ denotes Elevated
T182 199-205 NNS denotes levels
T183 206-208 IN denotes of
T184 209-225 JJ denotes pro-inflammatory
T185 226-235 NNS denotes cytokines
T186 236-239 CC denotes and
T187 240-250 NNS denotes chemokines
T188 251-255 JJ denotes such
T189 256-258 IN denotes as
T190 259-262 NNP denotes TNF
T191 262-263 , denotes ,
T192 264-268 NNP denotes IL-6
T193 269-272 CC denotes and
T194 273-278 NNP denotes CXCL8
T195 279-282 VBP denotes are
T196 283-293 VBN denotes associated
T197 294-298 IN denotes with
T198 299-306 JJ denotes several
T199 307-312 JJ denotes human
T200 313-321 NNS denotes diseases
T201 322-331 VBG denotes including
T202 332-338 JJ denotes cystic
T203 339-347 NN denotes fibrosis
T204 347-348 , denotes ,
T205 349-358 JJ denotes pulmonary
T206 359-367 NN denotes fibrosis
T207 368-371 CC denotes and
T208 372-376 NNP denotes AIDS
T209 376-377 . denotes .
T210 378-381 DT denotes The
T211 382-385 NN denotes aim
T212 386-388 IN denotes of
T213 389-393 DT denotes this
T214 394-399 NN denotes study
T215 400-403 VBD denotes was
T216 404-406 TO denotes to
T217 407-418 VB denotes investigate
T218 419-422 DT denotes the
T219 423-427 NN denotes role
T220 428-430 IN denotes of
T221 431-434 DT denotes the
T222 435-448 NN denotes transcription
T223 449-456 NNS denotes factors
T224 456-457 , denotes ,
T225 458-462 NNP denotes AP-1
T226 463-466 CC denotes and
T227 467-472 NNP denotes NF-κB
T228 472-473 , denotes ,
T229 474-476 IN denotes in
T230 477-481 NNP denotes IL-6
T231 482-485 CC denotes and
T232 486-491 NNP denotes CXCL8
T233 492-502 NN denotes regulation
T234 503-505 IN denotes in
T235 506-512 NNP denotes Jurkat
T236 513-520 NNS denotes T-cells
T237 520-521 . denotes .
T147 0-10 NNP denotes Background
T148 11-20 NNP denotes Activator
T149 21-28 NN denotes protein
T150 29-30 -LRB- denotes (
T151 30-32 NNP denotes AP
T152 32-33 -RRB- denotes )
T153 33-35 CD denotes -1
T154 36-39 CC denotes and
T155 40-47 JJ denotes nuclear
T156 48-54 NN denotes factor
T157 55-56 -LRB- denotes (
T158 56-58 NNP denotes NF
T159 58-59 -RRB- denotes )
T160 59-60 : denotes -
T161 60-62 NN denotes κB
T162 63-70 RB denotes largely
T163 71-78 JJ denotes control
T164 79-85 NNP denotes T-cell
T165 86-96 NN denotes activation
R58 T168 T167 pobj binding,following
R59 T169 T168 prep of,binding
R60 T170 T171 amod foreign,antigens
R61 T171 T169 pobj antigens,of
R62 T172 T168 prep to,binding
R63 T173 T175 det the,receptor
R56 T166 T165 punct ",",activation
R64 T174 T175 compound T-cell,receptor
R65 T175 T172 pobj receptor,to
R66 T176 T175 acl leading,receptor
R67 T177 T176 prep to,leading
R68 T178 T179 amod cytokine,secretion
R69 T179 T177 pobj secretion,to
R71 T181 T182 amod Elevated,levels
R72 T182 T196 nsubjpass levels,associated
R73 T183 T182 prep of,levels
R74 T184 T185 amod pro-inflammatory,cytokines
R75 T185 T183 pobj cytokines,of
R76 T186 T185 cc and,cytokines
R77 T187 T185 conj chemokines,cytokines
R78 T188 T189 amod such,as
R79 T189 T187 prep as,chemokines
R80 T190 T189 pobj TNF,as
R81 T191 T190 punct ",",TNF
R82 T192 T190 conj IL-6,TNF
R83 T193 T192 cc and,IL-6
R84 T194 T192 conj CXCL8,IL-6
R85 T195 T196 auxpass are,associated
R86 T196 T196 ROOT associated,associated
R87 T197 T196 prep with,associated
R88 T198 T200 amod several,diseases
R89 T199 T200 amod human,diseases
R90 T200 T197 pobj diseases,with
R91 T201 T200 prep including,diseases
R92 T202 T203 amod cystic,fibrosis
R93 T203 T201 pobj fibrosis,including
R94 T204 T203 punct ",",fibrosis
R95 T205 T206 amod pulmonary,fibrosis
R96 T206 T203 conj fibrosis,fibrosis
R97 T207 T206 cc and,fibrosis
R98 T208 T206 conj AIDS,fibrosis
R99 T209 T196 punct .,associated
R100 T210 T211 det The,aim
R101 T211 T215 nsubj aim,was
R102 T212 T211 prep of,aim
R103 T213 T214 det this,study
R104 T214 T212 pobj study,of
R105 T215 T215 ROOT was,was
R106 T216 T217 aux to,investigate
R107 T217 T215 xcomp investigate,was
R108 T218 T219 det the,role
R109 T219 T217 dobj role,investigate
R110 T220 T219 prep of,role
R111 T221 T223 det the,factors
R112 T222 T223 compound transcription,factors
R113 T223 T220 pobj factors,of
R114 T224 T219 punct ",",role
R115 T225 T233 nmod AP-1,regulation
R116 T226 T225 cc and,AP-1
R117 T227 T225 conj NF-κB,AP-1
R118 T228 T233 punct ",",regulation
R119 T229 T233 prep in,regulation
R120 T230 T229 pobj IL-6,in
R121 T231 T230 cc and,IL-6
R122 T232 T233 compound CXCL8,regulation
R123 T233 T217 dep regulation,investigate
R124 T234 T233 prep in,regulation
R125 T235 T236 compound Jurkat,T-cells
R126 T236 T234 pobj T-cells,in
R127 T237 T215 punct .,was
R967 T147 T148 compound Background,Activator
R968 T148 T149 compound Activator,protein
R970 T150 T151 punct (,AP
R971 T151 T149 appos AP,protein
R972 T152 T151 punct ),AP
R973 T153 T151 nummod -1,AP
R974 T154 T149 cc and,protein
R975 T155 T156 amod nuclear,factor
R976 T156 T149 conj factor,protein
R977 T157 T158 punct (,NF
R978 T158 T156 appos NF,factor
R979 T159 T158 punct ),NF
R980 T160 T161 punct -,κB
R981 T161 T165 amod κB,activation
R982 T162 T163 advmod largely,control
R983 T163 T165 amod control,activation
R984 T164 T165 compound T-cell,activation

GO-BP

Id Subject Object Predicate Lexical cue
T970 492-502 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T978 79-96 http://purl.obolibrary.org/obo/GO_0051132 denotes T-cell activation
T979 79-96 http://purl.obolibrary.org/obo/GO_0042110 denotes T-cell activation
T980 79-96 http://purl.obolibrary.org/obo/GO_0050798 denotes T-cell activation
T981 79-96 http://purl.obolibrary.org/obo/GO_0050863 denotes T-cell activation
T982 79-96 http://purl.obolibrary.org/obo/GO_1903905 denotes T-cell activation
T983 81-96 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T984 170-188 http://purl.obolibrary.org/obo/GO_0050663 denotes cytokine secretion
T985 179-188 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T986 435-448 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription

GO-MF

Id Subject Object Predicate Lexical cue
T1003 108-115 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T1004 143-158 http://purl.obolibrary.org/obo/GO_0042608 denotes T-cell receptor
T1005 264-268 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T1006 477-481 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6

GO-CC

Id Subject Object Predicate Lexical cue
T1019 515-520 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1021 143-158 http://purl.obolibrary.org/obo/GO_0042101 denotes T-cell receptor

sentences

Id Subject Object Predicate Lexical cue
T120 0-10 Sentence denotes Background
T121 11-189 Sentence denotes Activator protein (AP)-1 and nuclear factor (NF)-κB largely control T-cell activation, following binding of foreign antigens to the T-cell receptor leading to cytokine secretion.
T122 190-377 Sentence denotes Elevated levels of pro-inflammatory cytokines and chemokines such as TNF, IL-6 and CXCL8 are associated with several human diseases including cystic fibrosis, pulmonary fibrosis and AIDS.
T123 378-521 Sentence denotes The aim of this study was to investigate the role of the transcription factors, AP-1 and NF-κB, in IL-6 and CXCL8 regulation in Jurkat T-cells.
T3 0-10 Sentence denotes Background
T4 11-189 Sentence denotes Activator protein (AP)-1 and nuclear factor (NF)-κB largely control T-cell activation, following binding of foreign antigens to the T-cell receptor leading to cytokine secretion.
T5 190-377 Sentence denotes Elevated levels of pro-inflammatory cytokines and chemokines such as TNF, IL-6 and CXCL8 are associated with several human diseases including cystic fibrosis, pulmonary fibrosis and AIDS.
T6 378-521 Sentence denotes The aim of this study was to investigate the role of the transcription factors, AP-1 and NF-κB, in IL-6 and CXCL8 regulation in Jurkat T-cells.

ICD10

Id Subject Object Predicate Lexical cue
T1002 332-358 http://purl.bioontology.org/ontology/ICD10/E84.0 denotes cystic fibrosis, pulmonary
T1000 332-347 http://purl.bioontology.org/ontology/ICD10/E84 denotes cystic fibrosis
T1001 332-347 http://purl.bioontology.org/ontology/ICD10/E84.9 denotes cystic fibrosis

events-check-again

Id Subject Object Predicate Lexical cue Negation
T1212 264-268 Protein denotes IL-6
T1213 273-278 Protein denotes CXCL8
T1214 423-427 Regulation denotes role true
T1215 423-427 Regulation denotes role true
T1216 477-481 Protein denotes IL-6
T1217 486-491 Protein denotes CXCL8
T1218 492-502 Regulation denotes regulation
T1219 492-502 Regulation denotes regulation
R877 T1216 T1219 themeOf IL-6,regulation
R878 T1217 T1218 themeOf CXCL8,regulation
R879 T1218 T1214 themeOf regulation,role
R880 T1219 T1215 themeOf regulation,role

bionlp-st-ge-2016-reference-tees

Id Subject Object Predicate Lexical cue
T1254 60-62 Protein denotes κB
T1255 108-115 Binding denotes binding
T1256 259-262 Protein denotes TNF
T1257 264-268 Protein denotes IL-6
T1258 273-278 Protein denotes CXCL8
T1259 458-462 Protein denotes AP-1
T1260 467-472 Protein denotes NF-κB
T1261 477-481 Protein denotes IL-6
T1262 486-491 Protein denotes CXCL8
T1263 492-502 Regulation denotes regulation
T1264 492-502 Regulation denotes regulation
T1265 423-427 Regulation denotes role
T1266 423-427 Regulation denotes role
R898 T1254 T1255 themeOf κB,binding
R899 T1261 T1263 themeOf IL-6,regulation
R900 T1262 T1264 themeOf CXCL8,regulation
R901 T1263 T1265 themeOf regulation,role
R902 T1264 T1266 themeOf regulation,role

bionlp-st-ge-2016-reference

Id Subject Object Predicate Lexical cue Negation
T79 264-268 Protein denotes IL-6
T80 273-278 Protein denotes CXCL8
T81 423-427 Regulation denotes role true
T82 423-427 Regulation denotes role true
T83 477-481 Protein denotes IL-6
T84 486-491 Protein denotes CXCL8
T85 492-502 Regulation denotes regulation
T86 492-502 Regulation denotes regulation
R45 T83 T86 themeOf IL-6,regulation
R48 T86 T82 themeOf regulation,role
R46 T84 T85 themeOf CXCL8,regulation
R47 T85 T81 themeOf regulation,role

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T928 382-385 P26358 denotes aim
T929 458-462 P05412 denotes AP-1
T930 477-481 P05231 denotes IL-6
T931 486-491 P10145 denotes CXCL8
T925 259-262 P01375 denotes TNF
T926 264-268 P05231 denotes IL-6
T927 273-278 P10145 denotes CXCL8

test2

Id Subject Object Predicate Lexical cue Negation
T41 264-268 Protein denotes IL-6 true
T42 273-278 Protein denotes CXCL8
T43 283-293 Binding denotes associated true
T44 423-427 Regulation denotes role
T45 477-481 Protein denotes IL-6
T46 486-491 Protein denotes CXCL8
T47 492-502 Regulation denotes regulation
R22 T41 T43 themeOf IL-6,associated
R23 T42 T43 themeOf CXCL8,associated
R24 T45 T47 themeOf IL-6,regulation
R25 T46 T47 themeOf CXCL8,regulation