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2 NF-κB down-regulation by PMA and up-regulation by heat killed E. coli MG1655 following long-term stimulation. Transfection of Jurkat T-cells was performed using luciferase reporter plasmids containing NF-κB cis-elements. (A) Time-dependent stimulation of Jurkat T-cells using PMA. NF-κB activation was evaluated using HK E. coli in a (B) dose- and (C) time-dependant manner. Calcium ionophore increased NF-κB activity following PMA exposure (E) and resulted in a negative regulation in response to HK E. coli stimulation (D). Statistical significance from the control was determined using Student's t-test. (n = 4). Controls were arbitrarily set to 1.\n\n"}

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{"project":"sentences","denotations":[{"id":"T15303","span":{"begin":10,"end":119},"obj":"Sentence"},{"id":"T15304","span":{"begin":120,"end":290},"obj":"Sentence"},{"id":"T15305","span":{"begin":291,"end":384},"obj":"Sentence"},{"id":"T15306","span":{"begin":385,"end":535},"obj":"Sentence"},{"id":"T15307","span":{"begin":536,"end":625},"obj":"Sentence"},{"id":"T15308","span":{"begin":626,"end":661},"obj":"Sentence"},{"id":"T55","span":{"begin":0,"end":119},"obj":"Sentence"},{"id":"T56","span":{"begin":120,"end":290},"obj":"Sentence"},{"id":"T57","span":{"begin":291,"end":384},"obj":"Sentence"},{"id":"T58","span":{"begin":385,"end":535},"obj":"Sentence"},{"id":"T59","span":{"begin":536,"end":625},"obj":"Sentence"},{"id":"T60","span":{"begin":626,"end":661},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Figure 2 NF-κB down-regulation by PMA and up-regulation by heat killed E. coli MG1655 following long-term stimulation. Transfection of Jurkat T-cells was performed using luciferase reporter plasmids containing NF-κB cis-elements. (A) Time-dependent stimulation of Jurkat T-cells using PMA. NF-κB activation was evaluated using HK E. coli in a (B) dose- and (C) time-dependant manner. Calcium ionophore increased NF-κB activity following PMA exposure (E) and resulted in a negative regulation in response to HK E. coli stimulation (D). Statistical significance from the control was determined using Student's t-test. (n = 4). Controls were arbitrarily set to 1.\n\n"}

{"project":"events-check-again","denotations":[{"id":"T15561","span":{"begin":171,"end":181},"obj":"Protein"}],"text":"Figure 2 NF-κB down-regulation by PMA and up-regulation by heat killed E. coli MG1655 following long-term stimulation. Transfection of Jurkat T-cells was performed using luciferase reporter plasmids containing NF-κB cis-elements. (A) Time-dependent stimulation of Jurkat T-cells using PMA. NF-κB activation was evaluated using HK E. coli in a (B) dose- and (C) time-dependant manner. Calcium ionophore increased NF-κB activity following PMA exposure (E) and resulted in a negative regulation in response to HK E. coli stimulation (D). Statistical significance from the control was determined using Student's t-test. (n = 4). Controls were arbitrarily set to 1.\n\n"}

{"project":"bionlp-st-ge-2016-reference-tees","denotations":[{"id":"T15562","span":{"begin":10,"end":15},"obj":"Protein"},{"id":"T15563","span":{"begin":16,"end":31},"obj":"Negative_regulation"},{"id":"T15564","span":{"begin":43,"end":56},"obj":"Positive_regulation"},{"id":"T15565","span":{"begin":16,"end":31},"obj":"Negative_regulation"},{"id":"T15566","span":{"begin":171,"end":181},"obj":"Protein"},{"id":"T15567","span":{"begin":211,"end":216},"obj":"Protein"},{"id":"T15568","span":{"begin":291,"end":296},"obj":"Protein"},{"id":"T15569","span":{"begin":297,"end":307},"obj":"Positive_regulation"},{"id":"T15570","span":{"begin":413,"end":418},"obj":"Protein"},{"id":"T15571","span":{"begin":508,"end":510},"obj":"Protein"},{"id":"T15572","span":{"begin":403,"end":412},"obj":"Positive_regulation"}],"relations":[{"id":"R12642","pred":"themeOf","subj":"T15562","obj":"T15563"},{"id":"R12643","pred":"themeOf","subj":"T15563","obj":"T15564"},{"id":"R12644","pred":"themeOf","subj":"T15564","obj":"T15565"},{"id":"R12645","pred":"themeOf","subj":"T15568","obj":"T15569"},{"id":"R12646","pred":"themeOf","subj":"T15570","obj":"T15572"}],"text":"Figure 2 NF-κB down-regulation by PMA and up-regulation by heat killed E. coli MG1655 following long-term stimulation. Transfection of Jurkat T-cells was performed using luciferase reporter plasmids containing NF-κB cis-elements. (A) Time-dependent stimulation of Jurkat T-cells using PMA. NF-κB activation was evaluated using HK E. coli in a (B) dose- and (C) time-dependant manner. Calcium ionophore increased NF-κB activity following PMA exposure (E) and resulted in a negative regulation in response to HK E. coli stimulation (D). Statistical significance from the control was determined using Student's t-test. (n = 4). Controls were arbitrarily set to 1.\n\n"}

{"project":"bionlp-st-ge-2016-reference","denotations":[{"id":"T15302","span":{"begin":171,"end":181},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"Figure 2 NF-κB down-regulation by PMA and up-regulation by heat killed E. coli MG1655 following long-term stimulation. Transfection of Jurkat T-cells was performed using luciferase reporter plasmids containing NF-κB cis-elements. (A) Time-dependent stimulation of Jurkat T-cells using PMA. NF-κB activation was evaluated using HK E. coli in a (B) dose- and (C) time-dependant manner. Calcium ionophore increased NF-κB activity following PMA exposure (E) and resulted in a negative regulation in response to HK E. coli stimulation (D). Statistical significance from the control was determined using Student's t-test. (n = 4). Controls were arbitrarily set to 1.\n\n"}

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T15532","span":{"begin":171,"end":181},"obj":"P08659"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"Figure 2 NF-κB down-regulation by PMA and up-regulation by heat killed E. coli MG1655 following long-term stimulation. Transfection of Jurkat T-cells was performed using luciferase reporter plasmids containing NF-κB cis-elements. (A) Time-dependent stimulation of Jurkat T-cells using PMA. NF-κB activation was evaluated using HK E. coli in a (B) dose- and (C) time-dependant manner. Calcium ionophore increased NF-κB activity following PMA exposure (E) and resulted in a negative regulation in response to HK E. coli stimulation (D). Statistical significance from the control was determined using Student's t-test. (n = 4). Controls were arbitrarily set to 1.\n\n"}

{"project":"test2","denotations":[{"id":"T15301","span":{"begin":171,"end":181},"obj":"Protein"}],"text":"Figure 2 NF-κB down-regulation by PMA and up-regulation by heat killed E. coli MG1655 following long-term stimulation. Transfection of Jurkat T-cells was performed using luciferase reporter plasmids containing NF-κB cis-elements. (A) Time-dependent stimulation of Jurkat T-cells using PMA. NF-κB activation was evaluated using HK E. coli in a (B) dose- and (C) time-dependant manner. Calcium ionophore increased NF-κB activity following PMA exposure (E) and resulted in a negative regulation in response to HK E. coli stimulation (D). Statistical significance from the control was determined using Student's t-test. (n = 4). Controls were arbitrarily set to 1.\n\n"}