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1 AP-1 activation following long-term exposure of Jurkat T-cells to PMA. Jurkat T-cells were transfected with luciferase reporter plasmids containing the AP-1 cis-elements. (A) Time-dependent AP-1 activation in response to PMA. (B) HK E. coli does not activate AP-1. (C) Dose-dependent activation of AP-1 were performed using PMA alone (grey bars) and in combination with calcium ionophore (CaI 955 μM, black bars). (D) TCR-/- deficient cells responded to PMA (162 nM) by up-regulating AP-1 activity. Statistical significance from the control was determined using Student's t-test. (n = 4). Controls were arbitrarily set to 1. "}

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{"project":"GO-MF","denotations":[{"id":"T15275","span":{"begin":388,"end":397},"obj":"http://purl.obolibrary.org/obo/GO_0022809"}],"text":"Figure 1 AP-1 activation following long-term exposure of Jurkat T-cells to PMA. Jurkat T-cells were transfected with luciferase reporter plasmids containing the AP-1 cis-elements. (A) Time-dependent AP-1 activation in response to PMA. (B) HK E. coli does not activate AP-1. (C) Dose-dependent activation of AP-1 were performed using PMA alone (grey bars) and in combination with calcium ionophore (CaI 955 μM, black bars). (D) TCR-/- deficient cells responded to PMA (162 nM) by up-regulating AP-1 activity. Statistical significance from the control was determined using Student's t-test. (n = 4). Controls were arbitrarily set to 1. "}

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{"project":"sentences","denotations":[{"id":"T15023","span":{"begin":10,"end":80},"obj":"Sentence"},{"id":"T15024","span":{"begin":81,"end":508},"obj":"Sentence"},{"id":"T15025","span":{"begin":509,"end":598},"obj":"Sentence"},{"id":"T15026","span":{"begin":599,"end":634},"obj":"Sentence"},{"id":"T46","span":{"begin":0,"end":80},"obj":"Sentence"},{"id":"T47","span":{"begin":81,"end":508},"obj":"Sentence"},{"id":"T48","span":{"begin":509,"end":598},"obj":"Sentence"},{"id":"T49","span":{"begin":599,"end":634},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Figure 1 AP-1 activation following long-term exposure of Jurkat T-cells to PMA. Jurkat T-cells were transfected with luciferase reporter plasmids containing the AP-1 cis-elements. (A) Time-dependent AP-1 activation in response to PMA. (B) HK E. coli does not activate AP-1. (C) Dose-dependent activation of AP-1 were performed using PMA alone (grey bars) and in combination with calcium ionophore (CaI 955 μM, black bars). (D) TCR-/- deficient cells responded to PMA (162 nM) by up-regulating AP-1 activity. Statistical significance from the control was determined using Student's t-test. (n = 4). Controls were arbitrarily set to 1. "}

{"project":"events-check-again","denotations":[{"id":"T15286","span":{"begin":118,"end":128},"obj":"Protein"}],"text":"Figure 1 AP-1 activation following long-term exposure of Jurkat T-cells to PMA. Jurkat T-cells were transfected with luciferase reporter plasmids containing the AP-1 cis-elements. (A) Time-dependent AP-1 activation in response to PMA. (B) HK E. coli does not activate AP-1. (C) Dose-dependent activation of AP-1 were performed using PMA alone (grey bars) and in combination with calcium ionophore (CaI 955 μM, black bars). (D) TCR-/- deficient cells responded to PMA (162 nM) by up-regulating AP-1 activity. Statistical significance from the control was determined using Student's t-test. (n = 4). Controls were arbitrarily set to 1. "}

{"project":"bionlp-st-ge-2016-reference-tees","denotations":[{"id":"T15287","span":{"begin":10,"end":14},"obj":"Protein"},{"id":"T15288","span":{"begin":15,"end":25},"obj":"Positive_regulation"},{"id":"T15289","span":{"begin":118,"end":128},"obj":"Protein"},{"id":"T15290","span":{"begin":162,"end":166},"obj":"Protein"},{"id":"T15291","span":{"begin":200,"end":204},"obj":"Protein"},{"id":"T15292","span":{"begin":205,"end":215},"obj":"Positive_regulation"},{"id":"T15293","span":{"begin":269,"end":273},"obj":"Protein"},{"id":"T15294","span":{"begin":260,"end":268},"obj":"Positive_regulation"},{"id":"T15295","span":{"begin":308,"end":312},"obj":"Protein"},{"id":"T15296","span":{"begin":399,"end":409},"obj":"Protein"},{"id":"T15297","span":{"begin":294,"end":304},"obj":"Positive_regulation"},{"id":"T15298","span":{"begin":494,"end":498},"obj":"Protein"},{"id":"T15299","span":{"begin":480,"end":493},"obj":"Positive_regulation"}],"relations":[{"id":"R12415","pred":"themeOf","subj":"T15287","obj":"T15288"},{"id":"R12416","pred":"themeOf","subj":"T15291","obj":"T15292"},{"id":"R12417","pred":"themeOf","subj":"T15293","obj":"T15294"},{"id":"R12418","pred":"themeOf","subj":"T15295","obj":"T15297"},{"id":"R12419","pred":"themeOf","subj":"T15298","obj":"T15299"}],"text":"Figure 1 AP-1 activation following long-term exposure of Jurkat T-cells to PMA. Jurkat T-cells were transfected with luciferase reporter plasmids containing the AP-1 cis-elements. (A) Time-dependent AP-1 activation in response to PMA. (B) HK E. coli does not activate AP-1. (C) Dose-dependent activation of AP-1 were performed using PMA alone (grey bars) and in combination with calcium ionophore (CaI 955 μM, black bars). (D) TCR-/- deficient cells responded to PMA (162 nM) by up-regulating AP-1 activity. Statistical significance from the control was determined using Student's t-test. (n = 4). Controls were arbitrarily set to 1. "}

{"project":"bionlp-st-ge-2016-reference","denotations":[{"id":"T15022","span":{"begin":118,"end":128},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"Figure 1 AP-1 activation following long-term exposure of Jurkat T-cells to PMA. Jurkat T-cells were transfected with luciferase reporter plasmids containing the AP-1 cis-elements. (A) Time-dependent AP-1 activation in response to PMA. (B) HK E. coli does not activate AP-1. (C) Dose-dependent activation of AP-1 were performed using PMA alone (grey bars) and in combination with calcium ionophore (CaI 955 μM, black bars). (D) TCR-/- deficient cells responded to PMA (162 nM) by up-regulating AP-1 activity. Statistical significance from the control was determined using Student's t-test. (n = 4). Controls were arbitrarily set to 1. "}

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T15261","span":{"begin":10,"end":14},"obj":"P05412"},{"id":"T15262","span":{"begin":118,"end":128},"obj":"P08659"},{"id":"T15263","span":{"begin":162,"end":166},"obj":"P05412"},{"id":"T15264","span":{"begin":200,"end":204},"obj":"P05412"},{"id":"T15265","span":{"begin":269,"end":273},"obj":"P05412"},{"id":"T15266","span":{"begin":308,"end":312},"obj":"P05412"},{"id":"T15267","span":{"begin":494,"end":498},"obj":"P05412"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"Figure 1 AP-1 activation following long-term exposure of Jurkat T-cells to PMA. Jurkat T-cells were transfected with luciferase reporter plasmids containing the AP-1 cis-elements. (A) Time-dependent AP-1 activation in response to PMA. (B) HK E. coli does not activate AP-1. (C) Dose-dependent activation of AP-1 were performed using PMA alone (grey bars) and in combination with calcium ionophore (CaI 955 μM, black bars). (D) TCR-/- deficient cells responded to PMA (162 nM) by up-regulating AP-1 activity. Statistical significance from the control was determined using Student's t-test. (n = 4). Controls were arbitrarily set to 1. "}

{"project":"test2","denotations":[{"id":"T15021","span":{"begin":118,"end":128},"obj":"Protein"}],"text":"Figure 1 AP-1 activation following long-term exposure of Jurkat T-cells to PMA. Jurkat T-cells were transfected with luciferase reporter plasmids containing the AP-1 cis-elements. (A) Time-dependent AP-1 activation in response to PMA. (B) HK E. coli does not activate AP-1. (C) Dose-dependent activation of AP-1 were performed using PMA alone (grey bars) and in combination with calcium ionophore (CaI 955 μM, black bars). (D) TCR-/- deficient cells responded to PMA (162 nM) by up-regulating AP-1 activity. Statistical significance from the control was determined using Student's t-test. (n = 4). Controls were arbitrarily set to 1. "}