PMC:2889865 / 2175-2470 JSONTXT

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present study shows that NF-κB regulated IL-6 but not CXCL8. 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{"project":"GO-BP","denotations":[{"id":"T977","span":{"begin":89,"end":99},"obj":"http://purl.obolibrary.org/obo/GO_0065007"},{"id":"T992","span":{"begin":163,"end":173},"obj":"http://purl.obolibrary.org/obo/GO_0023052"},{"id":"T999","span":{"begin":163,"end":182},"obj":"http://purl.obolibrary.org/obo/GO_0007165"}],"text":"Conclusion\nThe present study shows that NF-κB regulated IL-6 but not CXCL8. This complex regulation of CXCL8 suggests that there is a need to further evaluate the signalling pathways in order to develop new treatment for diseases with elevated CXCL8 levels, such as AIDS and autoimmune diseases."}

{"project":"GO-MF","denotations":[{"id":"T1010","span":{"begin":56,"end":60},"obj":"http://purl.obolibrary.org/obo/GO_0005138"}],"text":"Conclusion\nThe present study shows that NF-κB regulated IL-6 but not CXCL8. This complex regulation of CXCL8 suggests that there is a need to further evaluate the signalling pathways in order to develop new treatment for diseases with elevated CXCL8 levels, such as AIDS and autoimmune diseases."}

{"project":"sentences","denotations":[{"id":"T134","span":{"begin":0,"end":10},"obj":"Sentence"},{"id":"T135","span":{"begin":11,"end":75},"obj":"Sentence"},{"id":"T136","span":{"begin":76,"end":295},"obj":"Sentence"},{"id":"T17","span":{"begin":0,"end":10},"obj":"Sentence"},{"id":"T18","span":{"begin":11,"end":75},"obj":"Sentence"},{"id":"T19","span":{"begin":76,"end":295},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Conclusion\nThe present study shows that NF-κB regulated IL-6 but not CXCL8. This complex regulation of CXCL8 suggests that there is a need to further evaluate the signalling pathways in order to develop new treatment for diseases with elevated CXCL8 levels, such as AIDS and autoimmune diseases."}

{"project":"events-check-again","denotations":[{"id":"T1244","span":{"begin":46,"end":55},"obj":"Regulation"},{"id":"T1245","span":{"begin":46,"end":55},"obj":"Regulation"},{"id":"T1246","span":{"begin":56,"end":60},"obj":"Protein"},{"id":"T1247","span":{"begin":69,"end":74},"obj":"Protein"},{"id":"T1248","span":{"begin":89,"end":99},"obj":"Regulation"},{"id":"T1249","span":{"begin":103,"end":108},"obj":"Protein"},{"id":"T1250","span":{"begin":235,"end":243},"obj":"Positive_regulation"},{"id":"T1251","span":{"begin":244,"end":249},"obj":"Protein"}],"relations":[{"id":"R894","pred":"themeOf","subj":"T1246","obj":"T1244"},{"id":"R895","pred":"themeOf","subj":"T1247","obj":"T1245"},{"id":"R896","pred":"themeOf","subj":"T1249","obj":"T1248"},{"id":"R897","pred":"themeOf","subj":"T1251","obj":"T1250"}],"attributes":[{"id":"M32","pred":"Negation","subj":"T1245","obj":"true"},{"id":"M31","pred":"Negation","subj":"T1244","obj":"true"}],"text":"Conclusion\nThe present study shows that NF-κB regulated IL-6 but not CXCL8. This complex regulation of CXCL8 suggests that there is a need to further evaluate the signalling pathways in order to develop new treatment for diseases with elevated CXCL8 levels, such as AIDS and autoimmune diseases."}

{"project":"bionlp-st-ge-2016-reference-tees","denotations":[{"id":"T1328","span":{"begin":40,"end":45},"obj":"Protein"},{"id":"T1329","span":{"begin":56,"end":60},"obj":"Protein"},{"id":"T1330","span":{"begin":69,"end":74},"obj":"Protein"},{"id":"T1331","span":{"begin":46,"end":55},"obj":"Regulation"},{"id":"T1332","span":{"begin":46,"end":55},"obj":"Regulation"},{"id":"T1333","span":{"begin":103,"end":108},"obj":"Protein"},{"id":"T1334","span":{"begin":244,"end":249},"obj":"Protein"},{"id":"T1335","span":{"begin":89,"end":99},"obj":"Regulation"},{"id":"T1336","span":{"begin":235,"end":243},"obj":"Positive_regulation"}],"relations":[{"id":"R941","pred":"causeOf","subj":"T1328","obj":"T1331"},{"id":"R942","pred":"causeOf","subj":"T1328","obj":"T1332"},{"id":"R943","pred":"themeOf","subj":"T1329","obj":"T1331"},{"id":"R944","pred":"themeOf","subj":"T1330","obj":"T1332"},{"id":"R945","pred":"themeOf","subj":"T1333","obj":"T1335"},{"id":"R946","pred":"themeOf","subj":"T1334","obj":"T1336"}],"text":"Conclusion\nThe present study shows that NF-κB regulated IL-6 but not CXCL8. This complex regulation of CXCL8 suggests that there is a need to further evaluate the signalling pathways in order to develop new treatment for diseases with elevated CXCL8 levels, such as AIDS and autoimmune diseases."}

{"project":"bionlp-st-ge-2016-reference","denotations":[{"id":"T111","span":{"begin":46,"end":55},"obj":"Regulation"},{"id":"T112","span":{"begin":46,"end":55},"obj":"Regulation"},{"id":"T113","span":{"begin":56,"end":60},"obj":"Protein"},{"id":"T114","span":{"begin":69,"end":74},"obj":"Protein"},{"id":"T115","span":{"begin":89,"end":99},"obj":"Regulation"},{"id":"T116","span":{"begin":103,"end":108},"obj":"Protein"},{"id":"T117","span":{"begin":235,"end":243},"obj":"Positive_regulation"},{"id":"T118","span":{"begin":244,"end":249},"obj":"Protein"}],"relations":[{"id":"R953","pred":"themeOf","subj":"T113","obj":"T111"},{"id":"R954","pred":"themeOf","subj":"T114","obj":"T112"},{"id":"R955","pred":"themeOf","subj":"T116","obj":"T115"},{"id":"R956","pred":"themeOf","subj":"T118","obj":"T117"}],"attributes":[{"id":"M34","pred":"Negation","subj":"T112","obj":"true"},{"id":"M33","pred":"Negation","subj":"T111","obj":"true"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"Conclusion\nThe present study shows that NF-κB regulated IL-6 but not CXCL8. This complex regulation of CXCL8 suggests that there is a need to further evaluate the signalling pathways in order to develop new treatment for diseases with elevated CXCL8 levels, such as AIDS and autoimmune diseases."}

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T947","span":{"begin":56,"end":60},"obj":"P05231"},{"id":"T948","span":{"begin":69,"end":74},"obj":"P10145"},{"id":"T949","span":{"begin":103,"end":108},"obj":"P10145"},{"id":"T950","span":{"begin":244,"end":249},"obj":"P10145"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"Conclusion\nThe present study shows that NF-κB regulated IL-6 but not CXCL8. This complex regulation of CXCL8 suggests that there is a need to further evaluate the signalling pathways in order to develop new treatment for diseases with elevated CXCL8 levels, such as AIDS and autoimmune diseases."}

{"project":"test2","denotations":[{"id":"T72","span":{"begin":46,"end":55},"obj":"Regulation"},{"id":"T73","span":{"begin":56,"end":60},"obj":"Protein"},{"id":"T74","span":{"begin":69,"end":74},"obj":"Protein"},{"id":"T75","span":{"begin":89,"end":99},"obj":"Regulation"},{"id":"T76","span":{"begin":103,"end":108},"obj":"Protein"},{"id":"T77","span":{"begin":235,"end":243},"obj":"Positive_regulation"},{"id":"T78","span":{"begin":244,"end":249},"obj":"Protein"}],"relations":[{"id":"R41","pred":"themeOf","subj":"T73","obj":"T72"},{"id":"R42","pred":"themeOf","subj":"T74","obj":"T72"},{"id":"R43","pred":"themeOf","subj":"T76","obj":"T75"},{"id":"R44","pred":"themeOf","subj":"T78","obj":"T77"}],"text":"Conclusion\nThe present study shows that NF-κB regulated IL-6 but not CXCL8. This complex regulation of CXCL8 suggests that there is a need to further evaluate the signalling pathways in order to develop new treatment for diseases with elevated CXCL8 levels, such as AIDS and autoimmune diseases."}