PMC:2889865 / 15754-16307 JSONTXT

{"project":"pmc-enju-pas","denotations":[{"id":"T16839","span":{"begin":10,"end":15},"obj":"NN"},{"id":"T16840","span":{"begin":16,"end":26},"obj":"NN"},{"id":"T16841","span":{"begin":27,"end":29},"obj":"IN"},{"id":"T16842","span":{"begin":30,"end":33},"obj":"NN"},{"id":"T16843","span":{"begin":34,"end":44},"obj":"VB"},{"id":"T16844","span":{"begin":45,"end":47},"obj":"TO"},{"id":"T16845","span":{"begin":48,"end":61},"obj":"JJ"},{"id":"T16846","span":{"begin":62,"end":67},"obj":"NN"},{"id":"T16847","span":{"begin":68,"end":79},"obj":"NN"},{"id":"T16848","span":{"begin":81,"end":87},"obj":"NN"},{"id":"T16849","span":{"begin":88,"end":90},"obj":"IN"},{"id":"T16850","span":{"begin":91,"end":104},"obj":"JJ"},{"id":"T16851","span":{"begin":105,"end":112},"obj":"NN"},{"id":"T16852","span":{"begin":113,"end":117},"obj":"VB"},{"id":"T16853","span":{"begin":118,"end":126},"obj":"VB"},{"id":"T16854","span":{"begin":127,"end":136},"obj":"VB"},{"id":"T16855","span":{"begin":137,"end":139},"obj":"CD"},{"id":"T16856","span":{"begin":140,"end":141},"obj":"NN"},{"id":"T16857","span":{"begin":142,"end":153},"obj":"NN"},{"id":"T16858","span":{"begin":154,"end":158},"obj":"IN"},{"id":"T16859","span":{"begin":159,"end":162},"obj":"NN"},{"id":"T16860","span":{"begin":163,"end":164},"obj":"-LRB-"},{"id":"T16861","span":{"begin":164,"end":167},"obj":"CD"},{"id":"T16862","span":{"begin":168,"end":170},"obj":"NN"},{"id":"T16863","span":{"begin":170,"end":171},"obj":"-RRB-"},{"id":"T16864","span":{"begin":172,"end":174},"obj":"CC"},{"id":"T16865","span":{"begin":175,"end":177},"obj":"NN"},{"id":"T16866","span":{"begin":178,"end":180},"obj":"FW"},{"id":"T16867","span":{"begin":181,"end":185},"obj":"FW"},{"id":"T16868","span":{"begin":186,"end":187},"obj":"-LRB-"},{"id":"T16869","span":{"begin":187,"end":188},"obj":"CD"},{"id":"T16870","span":{"begin":189,"end":190},"obj":"NN"},{"id":"T16871","span":{"begin":191,"end":194},"obj":"CD"},{"id":"T16872","span":{"begin":195,"end":201},"obj":"NNP"},{"id":"T16873","span":{"begin":201,"end":202},"obj":"-RRB-"},{"id":"T16874","span":{"begin":202,"end":203},"obj":"-LRB-"},{"id":"T16875","span":{"begin":204,"end":205},"obj":"NN"},{"id":"T16876","span":{"begin":205,"end":206},"obj":"-RRB-"},{"id":"T16877","span":{"begin":206,"end":217},"obj":"NN"},{"id":"T16878","span":{"begin":217,"end":226},"obj":"VB"},{"id":"T16879","span":{"begin":226,"end":228},"obj":"IN"},{"id":"T16880","span":{"begin":228,"end":236},"obj":"NN"},{"id":"T16881","span":{"begin":236,"end":238},"obj":"TO"},{"id":"T16882","span":{"begin":238,"end":241},"obj":"NN"},{"id":"T16883","span":{"begin":242,"end":245},"obj":"CC"},{"id":"T16884","span":{"begin":245,"end":247},"obj":"NN"},{"id":"T16885","span":{"begin":247,"end":249},"obj":"FW"},{"id":"T16886","span":{"begin":249,"end":253},"obj":"FW"},{"id":"T16887","span":{"begin":253,"end":265},"obj":"NN"},{"id":"T16888","span":{"begin":265,"end":266},"obj":"-LRB-"},{"id":"T16889","span":{"begin":266,"end":267},"obj":"NN"},{"id":"T16890","span":{"begin":267,"end":268},"obj":"-RRB-"},{"id":"T16891","span":{"begin":268,"end":271},"obj":"NN"},{"id":"T16892","span":{"begin":271,"end":280},"obj":"VB"},{"id":"T16893","span":{"begin":281,"end":290},"obj":"VB"},{"id":"T16894","span":{"begin":290,"end":301},"obj":"NN"},{"id":"T16895","span":{"begin":301,"end":305},"obj":"IN"},{"id":"T16896","span":{"begin":305,"end":307},"obj":"NN"},{"id":"T16897","span":{"begin":307,"end":309},"obj":"FW"},{"id":"T16898","span":{"begin":309,"end":313},"obj":"FW"},{"id":"T16899","span":{"begin":313,"end":323},"obj":"VB"},{"id":"T16900","span":{"begin":323,"end":328},"obj":"NN"},{"id":"T16901","span":{"begin":328,"end":339},"obj":"NN"},{"id":"T16902","span":{"begin":339,"end":340},"obj":"-LRB-"},{"id":"T16903","span":{"begin":340,"end":341},"obj":"NN"},{"id":"T16904","span":{"begin":341,"end":342},"obj":"-RRB-"},{"id":"T16905","span":{"begin":342,"end":347},"obj":"NN"},{"id":"T16906","span":{"begin":347,"end":357},"obj":"NN"},{"id":"T16907","span":{"begin":357,"end":360},"obj":"VB"},{"id":"T16908","span":{"begin":360,"end":369},"obj":"VB"},{"id":"T16909","span":{"begin":369,"end":378},"obj":"VB"},{"id":"T16910","span":{"begin":378,"end":387},"obj":"JJ"},{"id":"T16911","span":{"begin":387,"end":398},"obj":"NN"},{"id":"T16912","span":{"begin":398,"end":402},"obj":"IN"},{"id":"T16913","span":{"begin":402,"end":405},"obj":"NN"},{"id":"T16914","span":{"begin":405,"end":406},"obj":"-COMMA-"},{"id":"T16915","span":{"begin":407,"end":412},"obj":"WDT"},{"id":"T16916","span":{"begin":412,"end":420},"obj":"VB"},{"id":"T16917","span":{"begin":420,"end":423},"obj":"DT"},{"id":"T16918","span":{"begin":423,"end":433},"obj":"JJ"},{"id":"T16919","span":{"begin":434,"end":440},"obj":"NN"},{"id":"T16920","span":{"begin":440,"end":442},"obj":"IN"},{"id":"T16921","span":{"begin":442,"end":445},"obj":"NN"},{"id":"T16922","span":{"begin":445,"end":447},"obj":"IN"},{"id":"T16923","span":{"begin":447,"end":452},"obj":"NN"},{"id":"T16924","span":{"begin":452,"end":463},"obj":"NN"},{"id":"T16925","span":{"begin":463,"end":470},"obj":"NN"},{"id":"T16926","span":{"begin":470,"end":473},"obj":"VB"},{"id":"T16927","span":{"begin":473,"end":477},"obj":"VB"},{"id":"T16928","span":{"begin":477,"end":479},"obj":"IN"},{"id":"T16929","span":{"begin":479,"end":480},"obj":"DT"},{"id":"T16930","span":{"begin":480,"end":487},"obj":"NN"},{"id":"T16931","span":{"begin":487,"end":495},"obj":"NN"},{"id":"T16932","span":{"begin":495,"end":496},"obj":"-LRB-"},{"id":"T16933","span":{"begin":496,"end":497},"obj":"NN"},{"id":"T16934","span":{"begin":497,"end":498},"obj":"SYM"},{"id":"T16935","span":{"begin":498,"end":499},"obj":"CD"},{"id":"T16936","span":{"begin":499,"end":500},"obj":"-RRB-"}],"relations":[{"id":"R13714","pred":"arg1Of","subj":"T16840","obj":"T16839"},{"id":"R13715","pred":"arg1Of","subj":"T16840","obj":"T16841"},{"id":"R13716","pred":"arg1Of","subj":"T16840","obj":"T16843"},{"id":"R13717","pred":"arg2Of","subj":"T16842","obj":"T16841"},{"id":"R13718","pred":"arg1Of","subj":"T16843","obj":"T16844"},{"id":"R13719","pred":"arg2Of","subj":"T16847","obj":"T16844"},{"id":"R13720","pred":"arg1Of","subj":"T16847","obj":"T16845"},{"id":"R13721","pred":"arg1Of","subj":"T16847","obj":"T16846"},{"id":"R13722","pred":"arg1Of","subj":"T16848","obj":"T16849"},{"id":"R13723","pred":"arg1Of","subj":"T16848","obj":"T16852"},{"id":"R13724","pred":"arg2Of","subj":"T16848","obj":"T16853"},{"id":"R13725","pred":"arg2Of","subj":"T16851","obj":"T16849"},{"id":"R13726","pred":"arg1Of","subj":"T16851","obj":"T16850"},{"id":"R13727","pred":"arg2Of","subj":"T16853","obj":"T16852"},{"id":"R13728","pred":"arg1Of","subj":"T16853","obj":"T16854"},{"id":"R13729","pred":"arg2Of","subj":"T16853","obj":"T16878"},{"id":"R13730","pred":"arg1Of","subj":"T16857","obj":"T16855"},{"id":"R13731","pred":"arg1Of","subj":"T16857","obj":"T16856"},{"id":"R13732","pred":"arg1Of","subj":"T16857","obj":"T16858"},{"id":"R13733","pred":"arg1Of","subj":"T16857","obj":"T16864"},{"id":"R13734","pred":"arg2Of","subj":"T16859","obj":"T16858"},{"id":"R13735","pred":"arg1Of","subj":"T16859","obj":"T16860"},{"id":"R13736","pred":"arg2Of","subj":"T16862","obj":"T16860"},{"id":"R13737","pred":"arg1Of","subj":"T16862","obj":"T16861"},{"id":"R13738","pred":"arg3Of","subj":"T16863","obj":"T16860"},{"id":"R13739","pred":"arg2Of","subj":"T16864","obj":"T16854"},{"id":"R13740","pred":"arg1Of","subj":"T16864","obj":"T16874"},{"id":"R13741","pred":"arg2Of","subj":"T16867","obj":"T16864"},{"id":"R13742","pred":"arg1Of","subj":"T16867","obj":"T16865"},{"id":"R13743","pred":"arg1Of","subj":"T16867","obj":"T16866"},{"id":"R13744","pred":"arg1Of","subj":"T16867","obj":"T16868"},{"id":"R13745","pred":"arg2Of","subj":"T16870","obj":"T16868"},{"id":"R13746","pred":"arg1Of","subj":"T16870","obj":"T16869"},{"id":"R13747","pred":"arg1Of","subj":"T16870","obj":"T16871"},{"id":"R13748","pred":"arg1Of","subj":"T16870","obj":"T16872"},{"id":"R13749","pred":"arg3Of","subj":"T16873","obj":"T16868"},{"id":"R13750","pred":"arg2Of","subj":"T16875","obj":"T16874"},{"id":"R13751","pred":"arg3Of","subj":"T16876","obj":"T16874"},{"id":"R13752","pred":"arg1Of","subj":"T16877","obj":"T16878"},{"id":"R13753","pred":"arg1Of","subj":"T16878","obj":"T16879"},{"id":"R13754","pred":"arg1Of","subj":"T16878","obj":"T16893"},{"id":"R13755","pred":"modOf","subj":"T16878","obj":"T16899"},{"id":"R13756","pred":"arg2Of","subj":"T16880","obj":"T16879"},{"id":"R13757","pred":"arg1Of","subj":"T16880","obj":"T16881"},{"id":"R13758","pred":"arg1Of","subj":"T16882","obj":"T16883"},{"id":"R13759","pred":"arg2Of","subj":"T16883","obj":"T16881"},{"id":"R13760","pred":"arg2Of","subj":"T16884","obj":"T16883"},{"id":"R13761","pred":"arg3Of","subj":"T16887","obj":"T16879"},{"id":"R13762","pred":"arg1Of","subj":"T16887","obj":"T16885"},{"id":"R13763","pred":"arg1Of","subj":"T16887","obj":"T16886"},{"id":"R13764","pred":"arg1Of","subj":"T16887","obj":"T16888"},{"id":"R13765","pred":"arg2Of","subj":"T16887","obj":"T16892"},{"id":"R13766","pred":"arg2Of","subj":"T16889","obj":"T16888"},{"id":"R13767","pred":"arg3Of","subj":"T16890","obj":"T16888"},{"id":"R13768","pred":"arg1Of","subj":"T16891","obj":"T16892"},{"id":"R13769","pred":"arg2Of","subj":"T16894","obj":"T16893"},{"id":"R13770","pred":"arg1Of","subj":"T16894","obj":"T16895"},{"id":"R13771","pred":"arg2Of","subj":"T16896","obj":"T16895"},{"id":"R13772","pred":"arg1Of","subj":"T16896","obj":"T16898"},{"id":"R13773","pred":"arg1Of","subj":"T16898","obj":"T16897"},{"id":"R13774","pred":"arg2Of","subj":"T16903","obj":"T16902"},{"id":"R13775","pred":"arg3Of","subj":"T16904","obj":"T16902"},{"id":"R13776","pred":"arg1Of","subj":"T16906","obj":"T16900"},{"id":"R13777","pred":"arg1Of","subj":"T16906","obj":"T16901"},{"id":"R13778","pred":"arg1Of","subj":"T16906","obj":"T16902"},{"id":"R13779","pred":"arg1Of","subj":"T16906","obj":"T16905"},{"id":"R13780","pred":"arg1Of","subj":"T16906","obj":"T16907"},{"id":"R13781","pred":"arg2Of","subj":"T16906","obj":"T16908"},{"id":"R13782","pred":"arg2Of","subj":"T16908","obj":"T16899"},{"id":"R13783","pred":"arg2Of","subj":"T16908","obj":"T16907"},{"id":"R13784","pred":"arg1Of","subj":"T16908","obj":"T16909"},{"id":"R13785","pred":"arg2Of","subj":"T16911","obj":"T16909"},{"id":"R13786","pred":"arg1Of","subj":"T16911","obj":"T16910"},{"id":"R13787","pred":"arg1Of","subj":"T16911","obj":"T16912"},{"id":"R13788","pred":"arg1Of","subj":"T16911","obj":"T16914"},{"id":"R13789","pred":"arg1Of","subj":"T16911","obj":"T16915"},{"id":"R13790","pred":"arg1Of","subj":"T16911","obj":"T16916"},{"id":"R13791","pred":"arg2Of","subj":"T16913","obj":"T16912"},{"id":"R13792","pred":"arg1Of","subj":"T16919","obj":"T16917"},{"id":"R13793","pred":"arg1Of","subj":"T16919","obj":"T16918"},{"id":"R13794","pred":"arg1Of","subj":"T16919","obj":"T16920"},{"id":"R13795","pred":"arg1Of","subj":"T16919","obj":"T16922"},{"id":"R13796","pred":"arg1Of","subj":"T16919","obj":"T16926"},{"id":"R13797","pred":"arg2Of","subj":"T16919","obj":"T16927"},{"id":"R13798","pred":"arg2Of","subj":"T16921","obj":"T16920"},{"id":"R13799","pred":"arg2Of","subj":"T16925","obj":"T16922"},{"id":"R13800","pred":"arg1Of","subj":"T16925","obj":"T16923"},{"id":"R13801","pred":"arg1Of","subj":"T16925","obj":"T16924"},{"id":"R13802","pred":"arg2Of","subj":"T16927","obj":"T16916"},{"id":"R13803","pred":"arg2Of","subj":"T16927","obj":"T16926"},{"id":"R13804","pred":"arg1Of","subj":"T16927","obj":"T16928"},{"id":"R13805","pred":"arg1Of","subj":"T16927","obj":"T16932"},{"id":"R13806","pred":"arg2Of","subj":"T16931","obj":"T16928"},{"id":"R13807","pred":"arg1Of","subj":"T16931","obj":"T16929"},{"id":"R13808","pred":"arg1Of","subj":"T16931","obj":"T16930"},{"id":"R13809","pred":"arg2Of","subj":"T16933","obj":"T16932"},{"id":"R13810","pred":"arg1Of","subj":"T16933","obj":"T16934"},{"id":"R13811","pred":"arg1Of","subj":"T16933","obj":"T16935"},{"id":"R13812","pred":"arg3Of","subj":"T16936","obj":"T16932"}],"namespaces":[{"prefix":"_base","uri":"http://kmcs.nii.ac.jp/enju/"}],"text":"Figure 7 NF-κB inhibition by PMA correlated to PKC-dependent Bcl10 degradation. Levels of intracellular protein were assessed following 24 h stimulation with PMA (162 nM) or HK E. coli (5 × 107 CFU/ml). (A) Phospho-PKC increased in response to PMA and HK E. coli stimulation. (B) IκB decreased following stimulation with HK E. coli indicating NF-κB activation. (C) Bcl10 activation was inhibited following long-term stimulation with PMA, which explains the inhibitory effect of PMA on NF-κB activation. β-actin was used as a loading control. (n = 3).\n\n"}

{"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T16734","span":{"begin":10,"end":15},"obj":"JJ"},{"id":"T16735","span":{"begin":16,"end":26},"obj":"NN"},{"id":"T16736","span":{"begin":27,"end":29},"obj":"IN"},{"id":"T16737","span":{"begin":30,"end":33},"obj":"NNP"},{"id":"T16738","span":{"begin":34,"end":44},"obj":"VBD"},{"id":"T16739","span":{"begin":45,"end":47},"obj":"TO"},{"id":"T16740","span":{"begin":48,"end":61},"obj":"JJ"},{"id":"T16741","span":{"begin":62,"end":67},"obj":"JJ"},{"id":"T16742","span":{"begin":68,"end":79},"obj":"NN"},{"id":"T16743","span":{"begin":79,"end":80},"obj":"."},{"id":"T16744","span":{"begin":81,"end":87},"obj":"NNS"},{"id":"T16745","span":{"begin":88,"end":90},"obj":"IN"},{"id":"T16746","span":{"begin":91,"end":104},"obj":"JJ"},{"id":"T16747","span":{"begin":105,"end":112},"obj":"NN"},{"id":"T16748","span":{"begin":113,"end":117},"obj":"VBD"},{"id":"T16749","span":{"begin":118,"end":126},"obj":"VBN"},{"id":"T16750","span":{"begin":127,"end":136},"obj":"VBG"},{"id":"T16751","span":{"begin":137,"end":139},"obj":"CD"},{"id":"T16752","span":{"begin":140,"end":141},"obj":"NN"},{"id":"T16753","span":{"begin":142,"end":153},"obj":"NN"},{"id":"T16754","span":{"begin":154,"end":158},"obj":"IN"},{"id":"T16755","span":{"begin":159,"end":162},"obj":"NNP"},{"id":"T16756","span":{"begin":163,"end":164},"obj":"-LRB-"},{"id":"T16757","span":{"begin":164,"end":167},"obj":"CD"},{"id":"T16758","span":{"begin":168,"end":170},"obj":"NNP"},{"id":"T16759","span":{"begin":170,"end":171},"obj":"-RRB-"},{"id":"T16760","span":{"begin":172,"end":174},"obj":"CC"},{"id":"T16761","span":{"begin":175,"end":177},"obj":"NNP"},{"id":"T16762","span":{"begin":178,"end":180},"obj":"NNP"},{"id":"T16763","span":{"begin":181,"end":185},"obj":"NNS"},{"id":"T16764","span":{"begin":186,"end":187},"obj":"-LRB-"},{"id":"T16765","span":{"begin":187,"end":188},"obj":"CD"},{"id":"T16766","span":{"begin":189,"end":190},"obj":"CD"},{"id":"T16767","span":{"begin":191,"end":194},"obj":"CD"},{"id":"T16768","span":{"begin":195,"end":201},"obj":"NNP"},{"id":"T16769","span":{"begin":201,"end":202},"obj":"-RRB-"},{"id":"T16770","span":{"begin":202,"end":203},"obj":"."},{"id":"T16771","span":{"begin":204,"end":205},"obj":"-LRB-"},{"id":"T16772","span":{"begin":205,"end":206},"obj":"NNP"},{"id":"T16773","span":{"begin":206,"end":207},"obj":"-RRB-"},{"id":"T16774","span":{"begin":208,"end":219},"obj":"NNP"},{"id":"T16775","span":{"begin":220,"end":229},"obj":"VBD"},{"id":"T16776","span":{"begin":230,"end":232},"obj":"IN"},{"id":"T16777","span":{"begin":233,"end":241},"obj":"NN"},{"id":"T16778","span":{"begin":242,"end":244},"obj":"TO"},{"id":"T16779","span":{"begin":245,"end":248},"obj":"NNP"},{"id":"T16780","span":{"begin":249,"end":252},"obj":"CC"},{"id":"T16781","span":{"begin":253,"end":255},"obj":"NNP"},{"id":"T16782","span":{"begin":256,"end":258},"obj":"NNP"},{"id":"T16783","span":{"begin":259,"end":263},"obj":"NNS"},{"id":"T16784","span":{"begin":264,"end":275},"obj":"NN"},{"id":"T16785","span":{"begin":275,"end":276},"obj":"."},{"id":"T16786","span":{"begin":277,"end":278},"obj":"-LRB-"},{"id":"T16787","span":{"begin":278,"end":279},"obj":"NNP"},{"id":"T16788","span":{"begin":279,"end":280},"obj":"-RRB-"},{"id":"T16789","span":{"begin":281,"end":284},"obj":"NNP"},{"id":"T16790","span":{"begin":285,"end":294},"obj":"VBD"},{"id":"T16791","span":{"begin":295,"end":304},"obj":"VBG"},{"id":"T16792","span":{"begin":305,"end":316},"obj":"NN"},{"id":"T16793","span":{"begin":317,"end":321},"obj":"IN"},{"id":"T16794","span":{"begin":322,"end":324},"obj":"NNP"},{"id":"T16795","span":{"begin":325,"end":327},"obj":"NNP"},{"id":"T16796","span":{"begin":328,"end":332},"obj":"NNS"},{"id":"T16797","span":{"begin":333,"end":343},"obj":"VBG"},{"id":"T16798","span":{"begin":344,"end":349},"obj":"JJ"},{"id":"T16799","span":{"begin":350,"end":360},"obj":"NN"},{"id":"T16800","span":{"begin":360,"end":361},"obj":"."},{"id":"T16801","span":{"begin":362,"end":363},"obj":"-LRB-"},{"id":"T16802","span":{"begin":363,"end":364},"obj":"$"},{"id":"T16803","span":{"begin":364,"end":365},"obj":"-RRB-"},{"id":"T16804","span":{"begin":366,"end":371},"obj":"JJ"},{"id":"T16805","span":{"begin":372,"end":382},"obj":"NN"},{"id":"T16806","span":{"begin":383,"end":386},"obj":"VBD"},{"id":"T16807","span":{"begin":387,"end":396},"obj":"VBN"},{"id":"T16808","span":{"begin":397,"end":406},"obj":"VBG"},{"id":"T16809","span":{"begin":407,"end":416},"obj":"JJ"},{"id":"T16810","span":{"begin":417,"end":428},"obj":"NN"},{"id":"T16811","span":{"begin":429,"end":433},"obj":"IN"},{"id":"T16812","span":{"begin":434,"end":437},"obj":"NNP"},{"id":"T16813","span":{"begin":437,"end":438},"obj":","},{"id":"T16814","span":{"begin":439,"end":444},"obj":"WDT"},{"id":"T16815","span":{"begin":445,"end":453},"obj":"VBZ"},{"id":"T16816","span":{"begin":454,"end":457},"obj":"DT"},{"id":"T16817","span":{"begin":458,"end":468},"obj":"JJ"},{"id":"T16818","span":{"begin":469,"end":475},"obj":"NN"},{"id":"T16819","span":{"begin":476,"end":478},"obj":"IN"},{"id":"T16820","span":{"begin":479,"end":482},"obj":"NNP"},{"id":"T16821","span":{"begin":483,"end":485},"obj":"IN"},{"id":"T16822","span":{"begin":486,"end":491},"obj":"NNP"},{"id":"T16823","span":{"begin":492,"end":502},"obj":"NN"},{"id":"T16824","span":{"begin":502,"end":503},"obj":"."},{"id":"T16825","span":{"begin":504,"end":511},"obj":"NN"},{"id":"T16826","span":{"begin":512,"end":515},"obj":"VBD"},{"id":"T16827","span":{"begin":516,"end":520},"obj":"VBN"},{"id":"T16828","span":{"begin":521,"end":523},"obj":"IN"},{"id":"T16829","span":{"begin":524,"end":525},"obj":"DT"},{"id":"T16830","span":{"begin":526,"end":533},"obj":"VBG"},{"id":"T16831","span":{"begin":534,"end":541},"obj":"NN"},{"id":"T16832","span":{"begin":541,"end":542},"obj":"."},{"id":"T16833","span":{"begin":543,"end":544},"obj":"-LRB-"},{"id":"T16834","span":{"begin":544,"end":545},"obj":"FW"},{"id":"T16835","span":{"begin":546,"end":547},"obj":"SYM"},{"id":"T16836","span":{"begin":548,"end":549},"obj":"LS"},{"id":"T16837","span":{"begin":549,"end":550},"obj":"-RRB-"},{"id":"T16838","span":{"begin":550,"end":551},"obj":"."}],"relations":[{"id":"R13609","pred":"amod","subj":"T16734","obj":"T16735"},{"id":"R13610","pred":"nsubj","subj":"T16735","obj":"T16738"},{"id":"R13611","pred":"prep","subj":"T16736","obj":"T16735"},{"id":"R13612","pred":"pobj","subj":"T16737","obj":"T16736"},{"id":"R13613","pred":"ROOT","subj":"T16738","obj":"T16738"},{"id":"R13614","pred":"prep","subj":"T16739","obj":"T16738"},{"id":"R13615","pred":"amod","subj":"T16740","obj":"T16742"},{"id":"R13616","pred":"amod","subj":"T16741","obj":"T16742"},{"id":"R13617","pred":"pobj","subj":"T16742","obj":"T16739"},{"id":"R13618","pred":"punct","subj":"T16743","obj":"T16738"},{"id":"R13619","pred":"nsubjpass","subj":"T16744","obj":"T16749"},{"id":"R13620","pred":"prep","subj":"T16745","obj":"T16744"},{"id":"R13621","pred":"amod","subj":"T16746","obj":"T16747"},{"id":"R13622","pred":"pobj","subj":"T16747","obj":"T16745"},{"id":"R13623","pred":"auxpass","subj":"T16748","obj":"T16749"},{"id":"R13624","pred":"ROOT","subj":"T16749","obj":"T16749"},{"id":"R13625","pred":"prep","subj":"T16750","obj":"T16749"},{"id":"R13626","pred":"nummod","subj":"T16751","obj":"T16753"},{"id":"R13627","pred":"compound","subj":"T16752","obj":"T16753"},{"id":"R13628","pred":"pobj","subj":"T16753","obj":"T16750"},{"id":"R13629","pred":"prep","subj":"T16754","obj":"T16753"},{"id":"R13630","pred":"nmod","subj":"T16755","obj":"T16763"},{"id":"R13631","pred":"punct","subj":"T16756","obj":"T16758"},{"id":"R13632","pred":"nummod","subj":"T16757","obj":"T16758"},{"id":"R13633","pred":"appos","subj":"T16758","obj":"T16755"},{"id":"R13634","pred":"punct","subj":"T16759","obj":"T16758"},{"id":"R13635","pred":"cc","subj":"T16760","obj":"T16755"},{"id":"R13636","pred":"compound","subj":"T16761","obj":"T16763"},{"id":"R13637","pred":"compound","subj":"T16762","obj":"T16763"},{"id":"R13638","pred":"pobj","subj":"T16763","obj":"T16754"},{"id":"R13639","pred":"punct","subj":"T16764","obj":"T16763"},{"id":"R13640","pred":"nummod","subj":"T16765","obj":"T16768"},{"id":"R13641","pred":"nummod","subj":"T16766","obj":"T16768"},{"id":"R13642","pred":"nummod","subj":"T16767","obj":"T16768"},{"id":"R13643","pred":"appos","subj":"T16768","obj":"T16763"},{"id":"R13644","pred":"punct","subj":"T16769","obj":"T16763"},{"id":"R13645","pred":"punct","subj":"T16770","obj":"T16749"},{"id":"R13646","pred":"punct","subj":"T16771","obj":"T16774"},{"id":"R13647","pred":"nmod","subj":"T16772","obj":"T16774"},{"id":"R13648","pred":"punct","subj":"T16773","obj":"T16774"},{"id":"R13649","pred":"nsubj","subj":"T16774","obj":"T16775"},{"id":"R13650","pred":"ROOT","subj":"T16775","obj":"T16775"},{"id":"R13651","pred":"prep","subj":"T16776","obj":"T16775"},{"id":"R13652","pred":"pobj","subj":"T16777","obj":"T16776"},{"id":"R13653","pred":"prep","subj":"T16778","obj":"T16777"},{"id":"R13654","pred":"pobj","subj":"T16779","obj":"T16778"},{"id":"R13655","pred":"cc","subj":"T16780","obj":"T16779"},{"id":"R13656","pred":"compound","subj":"T16781","obj":"T16784"},{"id":"R13657","pred":"compound","subj":"T16782","obj":"T16784"},{"id":"R13658","pred":"compound","subj":"T16783","obj":"T16784"},{"id":"R13659","pred":"conj","subj":"T16784","obj":"T16779"},{"id":"R13660","pred":"punct","subj":"T16785","obj":"T16775"},{"id":"R13661","pred":"punct","subj":"T16786","obj":"T16790"},{"id":"R13662","pred":"nmod","subj":"T16787","obj":"T16789"},{"id":"R13663","pred":"punct","subj":"T16788","obj":"T16789"},{"id":"R13664","pred":"nsubj","subj":"T16789","obj":"T16790"},{"id":"R13665","pred":"ROOT","subj":"T16790","obj":"T16790"},{"id":"R13666","pred":"prep","subj":"T16791","obj":"T16790"},{"id":"R13667","pred":"pobj","subj":"T16792","obj":"T16791"},{"id":"R13668","pred":"prep","subj":"T16793","obj":"T16792"},{"id":"R13669","pred":"compound","subj":"T16794","obj":"T16796"},{"id":"R13670","pred":"compound","subj":"T16795","obj":"T16796"},{"id":"R13671","pred":"nsubj","subj":"T16796","obj":"T16797"},{"id":"R13672","pred":"pcomp","subj":"T16797","obj":"T16793"},{"id":"R13673","pred":"amod","subj":"T16798","obj":"T16799"},{"id":"R13674","pred":"dobj","subj":"T16799","obj":"T16797"},{"id":"R13675","pred":"punct","subj":"T16800","obj":"T16790"},{"id":"R13676","pred":"punct","subj":"T16801","obj":"T16802"},{"id":"R13677","pred":"nmod","subj":"T16802","obj":"T16805"},{"id":"R13678","pred":"punct","subj":"T16803","obj":"T16802"},{"id":"R13679","pred":"amod","subj":"T16804","obj":"T16805"},{"id":"R13680","pred":"nsubjpass","subj":"T16805","obj":"T16807"},{"id":"R13681","pred":"auxpass","subj":"T16806","obj":"T16807"},{"id":"R13682","pred":"ROOT","subj":"T16807","obj":"T16807"},{"id":"R13683","pred":"prep","subj":"T16808","obj":"T16807"},{"id":"R13684","pred":"amod","subj":"T16809","obj":"T16810"},{"id":"R13685","pred":"pobj","subj":"T16810","obj":"T16808"},{"id":"R13686","pred":"prep","subj":"T16811","obj":"T16810"},{"id":"R13687","pred":"pobj","subj":"T16812","obj":"T16811"},{"id":"R13688","pred":"punct","subj":"T16813","obj":"T16812"},{"id":"R13689","pred":"nsubj","subj":"T16814","obj":"T16815"},{"id":"R13690","pred":"relcl","subj":"T16815","obj":"T16812"},{"id":"R13691","pred":"det","subj":"T16816","obj":"T16818"},{"id":"R13692","pred":"amod","subj":"T16817","obj":"T16818"},{"id":"R13693","pred":"dobj","subj":"T16818","obj":"T16815"},{"id":"R13694","pred":"prep","subj":"T16819","obj":"T16818"},{"id":"R13695","pred":"pobj","subj":"T16820","obj":"T16819"},{"id":"R13696","pred":"prep","subj":"T16821","obj":"T16818"},{"id":"R13697","pred":"compound","subj":"T16822","obj":"T16823"},{"id":"R13698","pred":"pobj","subj":"T16823","obj":"T16821"},{"id":"R13699","pred":"punct","subj":"T16824","obj":"T16807"},{"id":"R13700","pred":"nsubjpass","subj":"T16825","obj":"T16827"},{"id":"R13701","pred":"auxpass","subj":"T16826","obj":"T16827"},{"id":"R13702","pred":"ROOT","subj":"T16827","obj":"T16827"},{"id":"R13703","pred":"prep","subj":"T16828","obj":"T16827"},{"id":"R13704","pred":"det","subj":"T16829","obj":"T16831"},{"id":"R13705","pred":"compound","subj":"T16830","obj":"T16831"},{"id":"R13706","pred":"pobj","subj":"T16831","obj":"T16828"},{"id":"R13707","pred":"punct","subj":"T16832","obj":"T16827"},{"id":"R13708","pred":"punct","subj":"T16833","obj":"T16836"},{"id":"R13709","pred":"advmod","subj":"T16834","obj":"T16836"},{"id":"R13710","pred":"punct","subj":"T16835","obj":"T16836"},{"id":"R13711","pred":"ROOT","subj":"T16836","obj":"T16836"},{"id":"R13712","pred":"punct","subj":"T16837","obj":"T16836"},{"id":"R13713","pred":"punct","subj":"T16838","obj":"T16836"}],"text":"Figure 7 NF-κB inhibition by PMA correlated to PKC-dependent Bcl10 degradation. Levels of intracellular protein were assessed following 24 h stimulation with PMA (162 nM) or HK E. coli (5 × 107 CFU/ml). (A) Phospho-PKC increased in response to PMA and HK E. coli stimulation. (B) IκB decreased following stimulation with HK E. coli indicating NF-κB activation. (C) Bcl10 activation was inhibited following long-term stimulation with PMA, which explains the inhibitory effect of PMA on NF-κB activation. β-actin was used as a loading control. (n = 3).\n\n"}

{"project":"GO-BP","denotations":[{"id":"T16942","span":{"begin":48,"end":51},"obj":"http://purl.obolibrary.org/obo/GO_0004697"},{"id":"T16943","span":{"begin":216,"end":219},"obj":"http://purl.obolibrary.org/obo/GO_0004697"},{"id":"T16944","span":{"begin":68,"end":79},"obj":"http://purl.obolibrary.org/obo/GO_0009056"},{"id":"T16945","span":{"begin":233,"end":248},"obj":"http://purl.obolibrary.org/obo/GO_1904627"},{"id":"T16946","span":{"begin":344,"end":360},"obj":"http://purl.obolibrary.org/obo/GO_0051092"},{"id":"T16947","span":{"begin":486,"end":502},"obj":"http://purl.obolibrary.org/obo/GO_0051092"}],"text":"Figure 7 NF-κB inhibition by PMA correlated to PKC-dependent Bcl10 degradation. Levels of intracellular protein were assessed following 24 h stimulation with PMA (162 nM) or HK E. coli (5 × 107 CFU/ml). (A) Phospho-PKC increased in response to PMA and HK E. coli stimulation. (B) IκB decreased following stimulation with HK E. coli indicating NF-κB activation. (C) Bcl10 activation was inhibited following long-term stimulation with PMA, which explains the inhibitory effect of PMA on NF-κB activation. β-actin was used as a loading control. (n = 3).\n\n"}

{"project":"GO-MF","denotations":[{"id":"T16948","span":{"begin":48,"end":51},"obj":"http://purl.obolibrary.org/obo/GO_0004697"},{"id":"T16949","span":{"begin":216,"end":219},"obj":"http://purl.obolibrary.org/obo/GO_0004697"}],"text":"Figure 7 NF-κB inhibition by PMA correlated to PKC-dependent Bcl10 degradation. Levels of intracellular protein were assessed following 24 h stimulation with PMA (162 nM) or HK E. coli (5 × 107 CFU/ml). (A) Phospho-PKC increased in response to PMA and HK E. coli stimulation. (B) IκB decreased following stimulation with HK E. coli indicating NF-κB activation. (C) Bcl10 activation was inhibited following long-term stimulation with PMA, which explains the inhibitory effect of PMA on NF-κB activation. β-actin was used as a loading control. (n = 3).\n\n"}

{"project":"GO-CC","denotations":[{"id":"T16950","span":{"begin":91,"end":104},"obj":"http://purl.obolibrary.org/obo/GO_0005622"}],"text":"Figure 7 NF-κB inhibition by PMA correlated to PKC-dependent Bcl10 degradation. Levels of intracellular protein were assessed following 24 h stimulation with PMA (162 nM) or HK E. coli (5 × 107 CFU/ml). (A) Phospho-PKC increased in response to PMA and HK E. coli stimulation. (B) IκB decreased following stimulation with HK E. coli indicating NF-κB activation. (C) Bcl10 activation was inhibited following long-term stimulation with PMA, which explains the inhibitory effect of PMA on NF-κB activation. β-actin was used as a loading control. (n = 3).\n\n"}

{"project":"sentences","denotations":[{"id":"T16732","span":{"begin":10,"end":80},"obj":"Sentence"},{"id":"T16733","span":{"begin":81,"end":551},"obj":"Sentence"},{"id":"T117","span":{"begin":0,"end":80},"obj":"Sentence"},{"id":"T118","span":{"begin":81,"end":551},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Figure 7 NF-κB inhibition by PMA correlated to PKC-dependent Bcl10 degradation. Levels of intracellular protein were assessed following 24 h stimulation with PMA (162 nM) or HK E. coli (5 × 107 CFU/ml). (A) Phospho-PKC increased in response to PMA and HK E. coli stimulation. (B) IκB decreased following stimulation with HK E. coli indicating NF-κB activation. (C) Bcl10 activation was inhibited following long-term stimulation with PMA, which explains the inhibitory effect of PMA on NF-κB activation. β-actin was used as a loading control. (n = 3).\n\n"}

{"project":"events-check-again","denotations":[{"id":"T16984","span":{"begin":52,"end":61},"obj":"Regulation"},{"id":"T16985","span":{"begin":62,"end":67},"obj":"Protein"},{"id":"T16986","span":{"begin":68,"end":79},"obj":"Protein_catabolism"},{"id":"T16987","span":{"begin":366,"end":371},"obj":"Protein"},{"id":"T16988","span":{"begin":372,"end":382},"obj":"Positive_regulation"},{"id":"T16989","span":{"begin":387,"end":396},"obj":"Negative_regulation"},{"id":"T16990","span":{"begin":504,"end":511},"obj":"Protein"}],"relations":[{"id":"R13831","pred":"themeOf","subj":"T16985","obj":"T16986"},{"id":"R13832","pred":"themeOf","subj":"T16986","obj":"T16984"},{"id":"R13833","pred":"themeOf","subj":"T16987","obj":"T16988"},{"id":"R13834","pred":"themeOf","subj":"T16988","obj":"T16989"}],"text":"Figure 7 NF-κB inhibition by PMA correlated to PKC-dependent Bcl10 degradation. Levels of intracellular protein were assessed following 24 h stimulation with PMA (162 nM) or HK E. coli (5 × 107 CFU/ml). (A) Phospho-PKC increased in response to PMA and HK E. coli stimulation. (B) IκB decreased following stimulation with HK E. coli indicating NF-κB activation. (C) Bcl10 activation was inhibited following long-term stimulation with PMA, which explains the inhibitory effect of PMA on NF-κB activation. β-actin was used as a loading control. (n = 3).\n\n"}

{"project":"bionlp-st-ge-2016-reference-tees","denotations":[{"id":"T16991","span":{"begin":10,"end":15},"obj":"Protein"},{"id":"T16992","span":{"begin":48,"end":51},"obj":"Protein"},{"id":"T16993","span":{"begin":16,"end":26},"obj":"Negative_regulation"},{"id":"T16994","span":{"begin":68,"end":79},"obj":"Protein_catabolism"},{"id":"T16995","span":{"begin":281,"end":284},"obj":"Protein"},{"id":"T16996","span":{"begin":322,"end":326},"obj":"Protein"},{"id":"T16997","span":{"begin":344,"end":349},"obj":"Protein"},{"id":"T16998","span":{"begin":350,"end":360},"obj":"Positive_regulation"},{"id":"T16999","span":{"begin":363,"end":364},"obj":"Protein"},{"id":"T17000","span":{"begin":366,"end":371},"obj":"Protein"},{"id":"T17001","span":{"begin":486,"end":491},"obj":"Protein"},{"id":"T17002","span":{"begin":504,"end":511},"obj":"Protein"},{"id":"T17003","span":{"begin":372,"end":382},"obj":"Positive_regulation"},{"id":"T17004","span":{"begin":387,"end":396},"obj":"Negative_regulation"}],"relations":[{"id":"R13835","pred":"themeOf","subj":"T16991","obj":"T16993"},{"id":"R13836","pred":"themeOf","subj":"T16992","obj":"T16994"},{"id":"R13837","pred":"themeOf","subj":"T16997","obj":"T16998"},{"id":"R13838","pred":"themeOf","subj":"T17000","obj":"T17003"},{"id":"R13839","pred":"themeOf","subj":"T17003","obj":"T17004"}],"text":"Figure 7 NF-κB inhibition by PMA correlated to PKC-dependent Bcl10 degradation. Levels of intracellular protein were assessed following 24 h stimulation with PMA (162 nM) or HK E. coli (5 × 107 CFU/ml). (A) Phospho-PKC increased in response to PMA and HK E. coli stimulation. (B) IκB decreased following stimulation with HK E. coli indicating NF-κB activation. (C) Bcl10 activation was inhibited following long-term stimulation with PMA, which explains the inhibitory effect of PMA on NF-κB activation. β-actin was used as a loading control. (n = 3).\n\n"}

{"project":"bionlp-st-ge-2016-reference","denotations":[{"id":"T16725","span":{"begin":52,"end":61},"obj":"Regulation"},{"id":"T16726","span":{"begin":62,"end":67},"obj":"Protein"},{"id":"T16727","span":{"begin":68,"end":79},"obj":"Protein_catabolism"},{"id":"T16728","span":{"begin":366,"end":371},"obj":"Protein"},{"id":"T16729","span":{"begin":372,"end":382},"obj":"Positive_regulation"},{"id":"T16730","span":{"begin":387,"end":396},"obj":"Negative_regulation"},{"id":"T16731","span":{"begin":504,"end":511},"obj":"Protein"}],"relations":[{"id":"R13605","pred":"themeOf","subj":"T16726","obj":"T16727"},{"id":"R13606","pred":"themeOf","subj":"T16727","obj":"T16725"},{"id":"R13607","pred":"themeOf","subj":"T16728","obj":"T16729"},{"id":"R13608","pred":"themeOf","subj":"T16729","obj":"T16730"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"Figure 7 NF-κB inhibition by PMA correlated to PKC-dependent Bcl10 degradation. Levels of intracellular protein were assessed following 24 h stimulation with PMA (162 nM) or HK E. coli (5 × 107 CFU/ml). (A) Phospho-PKC increased in response to PMA and HK E. coli stimulation. (B) IκB decreased following stimulation with HK E. coli indicating NF-κB activation. (C) Bcl10 activation was inhibited following long-term stimulation with PMA, which explains the inhibitory effect of PMA on NF-κB activation. β-actin was used as a loading control. (n = 3).\n\n"}

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T16937","span":{"begin":62,"end":67},"obj":"O95999"},{"id":"T16938","span":{"begin":366,"end":371},"obj":"O95999"},{"id":"T16939","span":{"begin":504,"end":511},"obj":"P60709"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"Figure 7 NF-κB inhibition by PMA correlated to PKC-dependent Bcl10 degradation. Levels of intracellular protein were assessed following 24 h stimulation with PMA (162 nM) or HK E. coli (5 × 107 CFU/ml). (A) Phospho-PKC increased in response to PMA and HK E. coli stimulation. (B) IκB decreased following stimulation with HK E. coli indicating NF-κB activation. (C) Bcl10 activation was inhibited following long-term stimulation with PMA, which explains the inhibitory effect of PMA on NF-κB activation. β-actin was used as a loading control. (n = 3).\n\n"}

{"project":"test2","denotations":[{"id":"T16717","span":{"begin":52,"end":61},"obj":"Regulation"},{"id":"T16718","span":{"begin":62,"end":67},"obj":"Protein"},{"id":"T16719","span":{"begin":68,"end":79},"obj":"Protein_catabolism"},{"id":"T16720","span":{"begin":366,"end":371},"obj":"Protein"},{"id":"T16721","span":{"begin":372,"end":382},"obj":"Positive_regulation"},{"id":"T16722","span":{"begin":387,"end":396},"obj":"Negative_regulation"},{"id":"T16723","span":{"begin":397,"end":406},"obj":"Positive_regulation"},{"id":"T16724","span":{"begin":504,"end":511},"obj":"Protein"}],"relations":[{"id":"R13600","pred":"themeOf","subj":"T16718","obj":"T16719"},{"id":"R13601","pred":"themeOf","subj":"T16719","obj":"T16717"},{"id":"R13602","pred":"themeOf","subj":"T16720","obj":"T16721"},{"id":"R13603","pred":"themeOf","subj":"T16721","obj":"T16723"},{"id":"R13604","pred":"themeOf","subj":"T16721","obj":"T16722"}],"text":"Figure 7 NF-κB inhibition by PMA correlated to PKC-dependent Bcl10 degradation. Levels of intracellular protein were assessed following 24 h stimulation with PMA (162 nM) or HK E. coli (5 × 107 CFU/ml). (A) Phospho-PKC increased in response to PMA and HK E. coli stimulation. (B) IκB decreased following stimulation with HK E. coli indicating NF-κB activation. (C) Bcl10 activation was inhibited following long-term stimulation with PMA, which explains the inhibitory effect of PMA on NF-κB activation. β-actin was used as a loading control. (n = 3).\n\n"}