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PMC:2889865 / 1291-1718
Annnotations
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T746 | 5-6 | -COMMA- | denotes | , |
T747 | 7-12 | NN | denotes | NF-κB |
T748 | 13-22 | VB | denotes | responded |
T749 | 23-25 | TO | denotes | to |
T750 | 26-29 | NN | denotes | PMA |
T751 | 30-38 | NN | denotes | exposure |
T752 | 39-41 | IN | denotes | by |
T753 | 42-43 | DT | denotes | a |
T754 | 44-49 | JJ | denotes | rapid |
T755 | 50-63 | NN | denotes | up-regulation |
T756 | 64-72 | VB | denotes | followed |
T757 | 73-75 | IN | denotes | by |
T758 | 76-77 | DT | denotes | a |
T759 | 78-88 | JJ | denotes | subsequent |
T760 | 89-104 | NN | denotes | down-regulation |
T761 | 106-115 | VB | denotes | Increased |
T762 | 116-129 | JJ | denotes | intracellular |
T763 | 130-134 | NN | denotes | Ca2+ |
T764 | 135-149 | NN | denotes | concentrations |
T765 | 150-159 | VB | denotes | countered |
T766 | 160-163 | DT | denotes | the |
T767 | 164-179 | NN | denotes | down-regulation |
T768 | 180-182 | IN | denotes | of |
T769 | 183-188 | NN | denotes | NF-κB |
T770 | 189-191 | IN | denotes | by |
T771 | 192-195 | NN | denotes | PMA |
T772 | 195-196 | -COMMA- | denotes | , |
T773 | 197-202 | IN | denotes | while |
T774 | 203-210 | JJ | denotes | similar |
T775 | 211-220 | NN | denotes | treatment |
T776 | 221-225 | IN | denotes | with |
T777 | 226-233 | NN | denotes | calcium |
T778 | 234-243 | NN | denotes | ionophore |
T779 | 244-252 | VB | denotes | resulted |
T780 | 253-255 | IN | denotes | in |
T781 | 256-257 | DT | denotes | a |
T782 | 258-265 | VB | denotes | reduced |
T783 | 266-271 | NN | denotes | NF-κB |
T784 | 272-280 | NN | denotes | activity |
T785 | 281-290 | VB | denotes | following |
T786 | 291-300 | NN | denotes | induction |
T787 | 301-305 | IN | denotes | with |
T788 | 306-308 | NN | denotes | HK |
T789 | 309-311 | FW | denotes | E. |
T790 | 312-316 | FW | denotes | coli |
T791 | 318-320 | IN | denotes | In |
T792 | 321-326 | NN | denotes | order |
T793 | 327-329 | TO | denotes | to |
T794 | 330-337 | JJ | denotes | further |
T795 | 338-343 | NN | denotes | study |
T796 | 344-349 | NN | denotes | NF-κB |
T797 | 350-360 | NN | denotes | activation |
T798 | 360-361 | -COMMA- | denotes | , |
T799 | 362-364 | PRP | denotes | we |
T800 | 365-375 | VB | denotes | considered |
T801 | 376-379 | CD | denotes | two |
T802 | 380-389 | JJ | denotes | up-stream |
T803 | 390-400 | NN | denotes | signalling |
T804 | 401-409 | NN | denotes | proteins |
T805 | 409-410 | -COMMA- | denotes | , |
T806 | 411-414 | NN | denotes | PKC |
T807 | 415-418 | CC | denotes | and |
T808 | 419-424 | NN | denotes | Bcl10 |
R633 | T747 | T748 | arg1Of | NF-κB,responded |
R635 | T748 | T746 | arg1Of | responded,"," |
R636 | T748 | T749 | arg1Of | responded,to |
R637 | T748 | T752 | arg1Of | responded,by |
R638 | T751 | T749 | arg2Of | exposure,to |
R639 | T751 | T750 | arg1Of | exposure,PMA |
R640 | T755 | T752 | arg2Of | up-regulation,by |
R641 | T755 | T753 | arg1Of | up-regulation,a |
R642 | T755 | T754 | arg1Of | up-regulation,rapid |
R643 | T755 | T756 | arg2Of | up-regulation,followed |
R644 | T760 | T756 | arg1Of | down-regulation,followed |
R645 | T760 | T757 | arg2Of | down-regulation,by |
R646 | T760 | T758 | arg1Of | down-regulation,a |
R647 | T760 | T759 | arg1Of | down-regulation,subsequent |
R648 | T764 | T761 | arg2Of | concentrations,Increased |
R649 | T764 | T762 | arg1Of | concentrations,intracellular |
R650 | T764 | T763 | arg1Of | concentrations,Ca2+ |
R651 | T764 | T765 | arg1Of | concentrations,countered |
R652 | T765 | T772 | arg1Of | countered,"," |
R653 | T765 | T773 | arg1Of | countered,while |
R654 | T767 | T765 | arg2Of | down-regulation,countered |
R655 | T767 | T766 | arg1Of | down-regulation,the |
R656 | T767 | T768 | arg1Of | down-regulation,of |
R657 | T767 | T770 | arg1Of | down-regulation,by |
R658 | T769 | T768 | arg2Of | NF-κB,of |
R659 | T771 | T770 | arg2Of | PMA,by |
R660 | T775 | T774 | arg1Of | treatment,similar |
R661 | T775 | T776 | arg1Of | treatment,with |
R662 | T775 | T779 | arg1Of | treatment,resulted |
R663 | T778 | T776 | arg2Of | ionophore,with |
R664 | T778 | T777 | arg1Of | ionophore,calcium |
R665 | T779 | T773 | arg2Of | resulted,while |
R666 | T779 | T780 | arg1Of | resulted,in |
R667 | T784 | T780 | arg2Of | activity,in |
R668 | T784 | T781 | arg1Of | activity,a |
R669 | T784 | T782 | arg2Of | activity,reduced |
R670 | T784 | T783 | arg1Of | activity,NF-κB |
R671 | T784 | T785 | arg1Of | activity,following |
R672 | T786 | T785 | arg2Of | induction,following |
R673 | T786 | T787 | arg1Of | induction,with |
R674 | T790 | T787 | arg2Of | coli,with |
R675 | T790 | T788 | arg1Of | coli,HK |
R676 | T790 | T789 | arg1Of | coli,E. |
R677 | T791 | T793 | arg1Of | In,to |
R678 | T792 | T791 | arg2Of | order,In |
R679 | T797 | T791 | arg3Of | activation,In |
R680 | T797 | T794 | arg1Of | activation,further |
R681 | T797 | T795 | arg1Of | activation,study |
R682 | T797 | T796 | arg1Of | activation,NF-κB |
R683 | T799 | T800 | arg1Of | we,considered |
R684 | T800 | T791 | arg1Of | considered,In |
R685 | T800 | T798 | arg1Of | considered,"," |
R686 | T804 | T800 | arg2Of | proteins,considered |
R687 | T804 | T801 | arg1Of | proteins,two |
R688 | T804 | T802 | arg1Of | proteins,up-stream |
R689 | T804 | T803 | arg1Of | proteins,signalling |
R690 | T804 | T805 | arg1Of | proteins,"," |
R691 | T806 | T807 | arg1Of | PKC,and |
R692 | T807 | T805 | arg2Of | and,"," |
R693 | T808 | T807 | arg2Of | Bcl10,and |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T352 | 5-6 | , | denotes | , |
T353 | 7-12 | NNP | denotes | NF-κB |
T354 | 13-22 | VBD | denotes | responded |
T355 | 23-25 | TO | denotes | to |
T356 | 26-29 | NNP | denotes | PMA |
T357 | 30-38 | NN | denotes | exposure |
T358 | 189-191 | IN | denotes | by |
T359 | 39-41 | IN | denotes | by |
T360 | 42-43 | DT | denotes | a |
T361 | 44-49 | JJ | denotes | rapid |
T362 | 50-63 | NN | denotes | up-regulation |
T363 | 64-72 | VBN | denotes | followed |
T364 | 73-75 | IN | denotes | by |
T365 | 76-77 | DT | denotes | a |
T366 | 78-88 | JJ | denotes | subsequent |
T367 | 89-104 | NN | denotes | down-regulation |
T368 | 104-105 | . | denotes | . |
T369 | 106-115 | VBN | denotes | Increased |
T370 | 116-129 | JJ | denotes | intracellular |
T371 | 130-133 | NNP | denotes | Ca2 |
T372 | 133-134 | NN | denotes | + |
T373 | 135-149 | NNS | denotes | concentrations |
T374 | 150-159 | VBD | denotes | countered |
T375 | 160-163 | DT | denotes | the |
T376 | 164-179 | NN | denotes | down-regulation |
T377 | 180-182 | IN | denotes | of |
T378 | 183-188 | NN | denotes | NF-κB |
T379 | 192-195 | NNP | denotes | PMA |
T380 | 195-196 | , | denotes | , |
T381 | 197-202 | IN | denotes | while |
T382 | 203-210 | JJ | denotes | similar |
T383 | 211-220 | NN | denotes | treatment |
T384 | 221-225 | IN | denotes | with |
T385 | 226-233 | NN | denotes | calcium |
T386 | 234-243 | NN | denotes | ionophore |
T387 | 244-252 | VBD | denotes | resulted |
T388 | 253-255 | IN | denotes | in |
T389 | 256-257 | DT | denotes | a |
T390 | 258-265 | VBN | denotes | reduced |
T391 | 266-271 | NN | denotes | NF-κB |
T392 | 272-280 | NN | denotes | activity |
T393 | 281-290 | VBG | denotes | following |
T394 | 291-300 | NN | denotes | induction |
T395 | 301-305 | IN | denotes | with |
T396 | 306-308 | NNP | denotes | HK |
T397 | 309-311 | NNP | denotes | E. |
T398 | 312-316 | NNS | denotes | coli |
T399 | 316-317 | . | denotes | . |
T400 | 318-320 | IN | denotes | In |
T401 | 321-326 | NN | denotes | order |
T402 | 327-329 | TO | denotes | to |
T403 | 330-337 | JJ | denotes | further |
T404 | 338-343 | NN | denotes | study |
T405 | 344-349 | NN | denotes | NF-κB |
T406 | 350-360 | NN | denotes | activation |
T407 | 360-361 | , | denotes | , |
T408 | 362-364 | PRP | denotes | we |
T409 | 365-375 | VBD | denotes | considered |
T410 | 376-379 | CD | denotes | two |
T411 | 380-389 | JJ | denotes | up-stream |
T412 | 390-400 | JJ | denotes | signalling |
T413 | 401-409 | NNS | denotes | proteins |
T414 | 409-410 | , | denotes | , |
T415 | 411-414 | NNP | denotes | PKC |
T416 | 415-418 | CC | denotes | and |
T417 | 419-424 | NNP | denotes | Bcl10 |
T418 | 424-425 | . | denotes | . |
R242 | T352 | T354 | punct | ",",responded |
R243 | T353 | T354 | nsubj | NF-κB,responded |
R244 | T354 | T354 | ROOT | responded,responded |
R245 | T355 | T354 | prep | to,responded |
R246 | T356 | T357 | compound | PMA,exposure |
R247 | T357 | T355 | pobj | exposure,to |
R248 | T358 | T376 | prep | by,down-regulation |
R249 | T359 | T357 | prep | by,exposure |
R250 | T360 | T362 | det | a,up-regulation |
R251 | T361 | T362 | amod | rapid,up-regulation |
R252 | T362 | T359 | pobj | up-regulation,by |
R253 | T363 | T357 | acl | followed,exposure |
R254 | T364 | T363 | agent | by,followed |
R255 | T365 | T367 | det | a,down-regulation |
R256 | T366 | T367 | amod | subsequent,down-regulation |
R257 | T367 | T364 | pobj | down-regulation,by |
R258 | T368 | T354 | punct | .,responded |
R259 | T369 | T373 | amod | Increased,concentrations |
R260 | T370 | T373 | amod | intracellular,concentrations |
R261 | T371 | T373 | compound | Ca2,concentrations |
R262 | T372 | T373 | compound | +,concentrations |
R263 | T373 | T374 | nsubj | concentrations,countered |
R264 | T374 | T374 | ROOT | countered,countered |
R265 | T375 | T376 | det | the,down-regulation |
R266 | T376 | T374 | dobj | down-regulation,countered |
R267 | T377 | T376 | prep | of,down-regulation |
R268 | T378 | T377 | pobj | NF-κB,of |
R269 | T379 | T358 | pobj | PMA,by |
R270 | T380 | T374 | punct | ",",countered |
R271 | T381 | T387 | mark | while,resulted |
R272 | T382 | T383 | amod | similar,treatment |
R273 | T383 | T387 | nsubj | treatment,resulted |
R274 | T384 | T383 | prep | with,treatment |
R275 | T385 | T386 | compound | calcium,ionophore |
R276 | T386 | T384 | pobj | ionophore,with |
R277 | T387 | T374 | advcl | resulted,countered |
R278 | T388 | T387 | prep | in,resulted |
R279 | T389 | T392 | det | a,activity |
R280 | T390 | T392 | amod | reduced,activity |
R281 | T391 | T392 | compound | NF-κB,activity |
R282 | T392 | T388 | pobj | activity,in |
R283 | T393 | T392 | acl | following,activity |
R284 | T394 | T393 | pobj | induction,following |
R285 | T395 | T394 | prep | with,induction |
R286 | T396 | T398 | compound | HK,coli |
R287 | T397 | T398 | compound | E.,coli |
R288 | T398 | T395 | pobj | coli,with |
R289 | T399 | T374 | punct | .,countered |
R290 | T400 | T409 | prep | In,considered |
R291 | T401 | T400 | pobj | order,In |
R292 | T402 | T404 | aux | to,study |
R293 | T403 | T404 | advmod | further,study |
R294 | T404 | T409 | advcl | study,considered |
R295 | T405 | T406 | compound | NF-κB,activation |
R296 | T406 | T404 | dobj | activation,study |
R297 | T407 | T409 | punct | ",",considered |
R298 | T408 | T409 | nsubj | we,considered |
R299 | T409 | T409 | ROOT | considered,considered |
R300 | T410 | T413 | nummod | two,proteins |
R301 | T411 | T413 | amod | up-stream,proteins |
R302 | T412 | T413 | amod | signalling,proteins |
R303 | T413 | T409 | dobj | proteins,considered |
R304 | T414 | T413 | punct | ",",proteins |
R305 | T415 | T413 | appos | PKC,proteins |
R306 | T416 | T415 | cc | and,PKC |
R307 | T417 | T415 | conj | Bcl10,PKC |
R308 | T418 | T409 | punct | .,considered |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T974 | 53-63 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
T975 | 94-104 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
T976 | 169-179 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
T988 | 234-243 | http://purl.obolibrary.org/obo/GO_0022809 | denotes | ionophore |
T989 | 344-360 | http://purl.obolibrary.org/obo/GO_0051092 | denotes | NF-κB activation |
T991 | 390-400 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signalling |
T993 | 411-414 | http://purl.obolibrary.org/obo/GO_0004697 | denotes | PKC |
GO-MF
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1013 | 234-243 | http://purl.obolibrary.org/obo/GO_0022809 | denotes | ionophore |
T1014 | 411-414 | http://purl.obolibrary.org/obo/GO_0004697 | denotes | PKC |
GO-CC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1022 | 116-129 | http://purl.obolibrary.org/obo/GO_0005622 | denotes | intracellular |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T129 | 106-317 | Sentence | denotes | Increased intracellular Ca2+ concentrations countered the down-regulation of NF-κB by PMA, while similar treatment with calcium ionophore resulted in a reduced NF-κB activity following induction with HK E. coli. |
T130 | 318-425 | Sentence | denotes | In order to further study NF-κB activation, we considered two up-stream signalling proteins, PKC and Bcl10. |
T12 | 106-317 | Sentence | denotes | Increased intracellular Ca2+ concentrations countered the down-regulation of NF-κB by PMA, while similar treatment with calcium ionophore resulted in a reduced NF-κB activity following induction with HK E. coli. |
T13 | 318-425 | Sentence | denotes | In order to further study NF-κB activation, we considered two up-stream signalling proteins, PKC and Bcl10. |
events-check-again
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1229 | 419-424 | Protein | denotes | Bcl10 |
bionlp-st-ge-2016-reference-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1292 | 7-12 | Protein | denotes | NF-κB |
T1293 | 50-63 | Positive_regulation | denotes | up-regulation |
T1294 | 89-104 | Negative_regulation | denotes | down-regulation |
T1295 | 50-63 | Positive_regulation | denotes | up-regulation |
T1296 | 183-188 | Protein | denotes | NF-κB |
T1297 | 266-271 | Protein | denotes | NF-κB |
T1298 | 306-316 | Protein | denotes | HK E. coli |
T1299 | 164-179 | Negative_regulation | denotes | down-regulation |
T1300 | 291-300 | Positive_regulation | denotes | induction |
T1301 | 258-265 | Negative_regulation | denotes | reduced |
T1302 | 347-349 | Protein | denotes | κB |
T1303 | 411-414 | Protein | denotes | PKC |
T1304 | 419-424 | Protein | denotes | Bcl10 |
T1305 | 350-360 | Positive_regulation | denotes | activation |
R920 | T1292 | T1293 | themeOf | NF-κB,up-regulation |
R921 | T1293 | T1294 | themeOf | up-regulation,down-regulation |
R922 | T1294 | T1295 | themeOf | down-regulation,up-regulation |
R923 | T1296 | T1299 | themeOf | NF-κB,down-regulation |
R924 | T1298 | T1300 | themeOf | HK E. coli,induction |
R925 | T1300 | T1301 | themeOf | induction,reduced |
R926 | T1302 | T1305 | themeOf | κB,activation |
bionlp-st-ge-2016-reference
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T96 | 419-424 | Protein | denotes | Bcl10 |
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T940 | 419-424 | O95999 | denotes | Bcl10 |
test2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T56 | 419-424 | Protein | denotes | Bcl10 |