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PMC:2889865 / 0-596 JSONTXT

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pmc-enju-pas

Id Subject Object Predicate Lexical cue
T539 0-12 JJ denotes Differential
T540 13-21 NN denotes cytokine
T541 22-32 NN denotes regulation
T542 33-35 IN denotes by
T543 36-41 NN denotes NF-κB
T544 42-45 CC denotes and
T545 46-50 NN denotes AP-1
T546 51-53 IN denotes in
T547 54-60 NN denotes Jurkat
T548 61-68 NN denotes T-cells
T549 80-90 NN denotes Background
T550 91-100 NN denotes Activator
T551 101-108 NN denotes protein
T552 109-110 -LRB- denotes (
T553 110-112 NN denotes AP
T554 112-113 -RRB- denotes )
T555 113-115 CD denotes -1
T556 116-119 CC denotes and
T557 120-127 JJ denotes nuclear
T558 128-134 NN denotes factor
T559 135-136 -LRB- denotes (
T560 136-138 NN denotes NF
T561 138-139 -RRB- denotes )
T562 139-142 NN denotes -κB
T563 143-150 RB denotes largely
T564 151-158 VB denotes control
T565 159-165 NN denotes T-cell
T566 166-176 NN denotes activation
T567 176-177 -COMMA- denotes ,
T568 178-187 VB denotes following
T569 188-195 NN denotes binding
T570 196-198 IN denotes of
T571 199-206 JJ denotes foreign
T572 207-215 NN denotes antigens
T573 216-218 TO denotes to
T574 219-222 DT denotes the
T575 223-229 NN denotes T-cell
T576 230-238 NN denotes receptor
T577 239-246 VB denotes leading
T578 247-249 TO denotes to
T579 250-258 NN denotes cytokine
T580 259-268 NN denotes secretion
T581 270-278 JJ denotes Elevated
T582 279-285 NN denotes levels
T583 286-288 IN denotes of
T584 289-305 JJ denotes pro-inflammatory
T585 306-315 NN denotes cytokines
T586 316-319 CC denotes and
T587 320-330 NN denotes chemokines
T588 331-335 JJ denotes such
T589 336-338 IN denotes as
T590 339-342 NN denotes TNF
T591 342-343 -COMMA- denotes ,
T592 344-348 NN denotes IL-6
T593 349-352 CC denotes and
T594 353-358 NN denotes CXCL8
T595 359-362 VB denotes are
T596 363-373 VB denotes associated
T597 374-378 IN denotes with
T598 379-386 JJ denotes several
T599 387-392 JJ denotes human
T600 393-401 NN denotes diseases
T601 402-411 VB denotes including
T602 412-418 JJ denotes cystic
T603 419-427 NN denotes fibrosis
T604 427-428 -COMMA- denotes ,
T605 429-438 JJ denotes pulmonary
T606 439-447 NN denotes fibrosis
T607 448-451 CC denotes and
T608 452-456 NN denotes AIDS
T609 458-461 DT denotes The
T610 462-465 NN denotes aim
T611 466-468 IN denotes of
T612 469-473 DT denotes this
T613 474-479 NN denotes study
T614 480-483 VB denotes was
T615 484-486 TO denotes to
T616 487-498 VB denotes investigate
T617 499-502 DT denotes the
T618 503-507 NN denotes role
T619 508-510 IN denotes of
T620 511-514 DT denotes the
T621 515-528 NN denotes transcription
T622 529-536 NN denotes factors
T623 536-537 -COMMA- denotes ,
T624 538-542 NN denotes AP-1
T625 543-546 CC denotes and
T626 547-552 NN denotes NF-κB
T627 552-553 -COMMA- denotes ,
T628 554-556 IN denotes in
T629 557-561 NN denotes IL-6
T630 562-565 CC denotes and
T631 566-571 NN denotes CXCL8
T632 572-582 NN denotes regulation
T633 583-585 IN denotes in
T634 586-592 NN denotes Jurkat
R428 T541 T539 arg1Of regulation,Differential
R429 T541 T540 arg1Of regulation,cytokine
R430 T541 T542 arg1Of regulation,by
R431 T541 T546 arg1Of regulation,in
R432 T543 T544 arg1Of NF-κB,and
R433 T544 T542 arg2Of and,by
R434 T545 T544 arg2Of AP-1,and
R435 T548 T546 arg2Of T-cells,in
R436 T548 T547 arg1Of T-cells,Jurkat
R437 T551 T550 arg1Of protein,Activator
R438 T551 T552 arg1Of protein,(
R439 T551 T555 arg1Of protein,-1
R440 T551 T556 arg1Of protein,and
R441 T553 T552 arg2Of AP,(
R442 T554 T552 arg3Of ),(
R443 T556 T564 arg1Of and,control
R444 T560 T559 arg2Of NF,(
R445 T561 T559 arg3Of ),(
R446 T562 T556 arg2Of -κB,and
R447 T562 T557 arg1Of -κB,nuclear
R448 T562 T558 arg1Of -κB,factor
R449 T562 T559 arg1Of -κB,(
R450 T564 T563 arg1Of control,largely
R451 T564 T567 arg1Of control,","
R452 T564 T568 arg1Of control,following
R453 T566 T564 arg2Of activation,control
R454 T566 T565 arg1Of activation,T-cell
R455 T569 T568 arg2Of binding,following
R456 T569 T570 arg1Of binding,of
R457 T569 T573 arg1Of binding,to
R458 T572 T570 arg2Of antigens,of
R459 T572 T571 arg1Of antigens,foreign
R460 T576 T573 arg2Of receptor,to
R461 T576 T574 arg1Of receptor,the
R462 T576 T575 arg1Of receptor,T-cell
R463 T576 T577 arg1Of receptor,leading
R464 T577 T578 arg1Of leading,to
R465 T580 T578 arg2Of secretion,to
R466 T580 T579 arg1Of secretion,cytokine
R467 T582 T581 arg1Of levels,Elevated
R468 T582 T583 arg1Of levels,of
R469 T582 T595 arg1Of levels,are
R470 T582 T596 arg2Of levels,associated
R471 T585 T586 arg1Of cytokines,and
R472 T586 T583 arg2Of and,of
R473 T586 T584 arg1Of and,pro-inflammatory
R474 T586 T589 arg1Of and,as
R475 T587 T586 arg2Of chemokines,and
R476 T589 T588 arg1Of as,such
R477 T590 T591 arg1Of TNF,","
R478 T591 T593 arg1Of ",",and
R479 T592 T591 arg2Of IL-6,","
R480 T593 T589 arg2Of and,as
R481 T594 T593 arg2Of CXCL8,and
R482 T596 T595 arg2Of associated,are
R483 T596 T597 arg1Of associated,with
R484 T600 T597 arg2Of diseases,with
R485 T600 T598 arg1Of diseases,several
R486 T600 T599 arg1Of diseases,human
R487 T600 T601 arg1Of diseases,including
R488 T603 T602 arg1Of fibrosis,cystic
R489 T603 T604 arg1Of fibrosis,","
R490 T604 T607 arg1Of ",",and
R491 T606 T604 arg2Of fibrosis,","
R492 T606 T605 arg1Of fibrosis,pulmonary
R493 T607 T601 arg2Of and,including
R494 T608 T607 arg2Of AIDS,and
R495 T610 T609 arg1Of aim,The
R496 T610 T611 arg1Of aim,of
R497 T610 T614 arg1Of aim,was
R498 T613 T611 arg2Of study,of
R499 T613 T612 arg1Of study,this
R500 T616 T614 arg2Of investigate,was
R501 T616 T615 arg1Of investigate,to
R502 T618 T616 arg2Of role,investigate
R503 T618 T617 arg1Of role,the
R504 T618 T619 arg1Of role,of
R505 T618 T627 arg1Of role,","
R506 T618 T628 arg1Of role,in
R507 T622 T619 arg2Of factors,of
R508 T622 T620 arg1Of factors,the
R509 T622 T621 arg1Of factors,transcription
R510 T622 T623 arg1Of factors,","
R511 T624 T625 arg1Of AP-1,and
R512 T625 T623 arg2Of and,","
R513 T626 T625 arg2Of NF-κB,and
R514 T629 T630 arg1Of IL-6,and
R515 T631 T630 arg2Of CXCL8,and
R516 T632 T628 arg2Of regulation,in
R517 T632 T629 arg1Of regulation,IL-6
R518 T632 T631 arg1Of regulation,CXCL8
R519 T632 T633 arg1Of regulation,in

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T166 176-177 , denotes ,
T167 178-187 VBG denotes following
T168 188-195 JJ denotes binding
T169 196-198 IN denotes of
T170 199-206 JJ denotes foreign
T171 207-215 NNS denotes antigens
T172 216-218 TO denotes to
T173 219-222 DT denotes the
T174 223-229 NN denotes T-cell
T175 230-238 NN denotes receptor
T176 239-246 VBG denotes leading
T177 247-249 TO denotes to
T178 250-258 VB denotes cytokine
T179 259-268 NN denotes secretion
T180 268-269 . denotes .
T181 270-278 JJ denotes Elevated
T182 279-285 NNS denotes levels
T183 286-288 IN denotes of
T184 289-305 JJ denotes pro-inflammatory
T185 306-315 NNS denotes cytokines
T186 316-319 CC denotes and
T187 320-330 NNS denotes chemokines
T188 331-335 JJ denotes such
T189 336-338 IN denotes as
T190 339-342 NNP denotes TNF
T191 342-343 , denotes ,
T192 344-348 NNP denotes IL-6
T193 349-352 CC denotes and
T194 353-358 NNP denotes CXCL8
T195 359-362 VBP denotes are
T196 363-373 VBN denotes associated
T197 374-378 IN denotes with
T198 379-386 JJ denotes several
T199 387-392 JJ denotes human
T200 393-401 NNS denotes diseases
T201 402-411 VBG denotes including
T202 412-418 JJ denotes cystic
T203 419-427 NN denotes fibrosis
T204 427-428 , denotes ,
T205 429-438 JJ denotes pulmonary
T206 439-447 NN denotes fibrosis
T207 448-451 CC denotes and
T208 452-456 NNP denotes AIDS
T209 456-457 . denotes .
T210 458-461 DT denotes The
T211 462-465 NN denotes aim
T212 466-468 IN denotes of
T213 469-473 DT denotes this
T214 474-479 NN denotes study
T215 480-483 VBD denotes was
T216 484-486 TO denotes to
T217 487-498 VB denotes investigate
T218 499-502 DT denotes the
T219 503-507 NN denotes role
T220 508-510 IN denotes of
T221 511-514 DT denotes the
T222 515-528 NN denotes transcription
T223 529-536 NNS denotes factors
T224 536-537 , denotes ,
T225 538-542 NNP denotes AP-1
T226 543-546 CC denotes and
T227 547-552 NNP denotes NF-κB
T228 552-553 , denotes ,
T229 554-556 IN denotes in
T230 557-561 NNP denotes IL-6
T231 562-565 CC denotes and
T232 566-571 NNP denotes CXCL8
T233 572-582 NN denotes regulation
T234 583-585 IN denotes in
T235 586-592 NNP denotes Jurkat
T137 0-12 NN denotes Differential
T138 13-21 NN denotes cytokine
T139 22-32 NN denotes regulation
T140 33-35 IN denotes by
T141 36-41 NNP denotes NF-κB
T142 42-45 CC denotes and
T143 46-50 NNP denotes AP-1
T144 51-53 IN denotes in
T145 54-60 NNP denotes Jurkat
T146 61-68 NNP denotes T-cells
T147 80-90 NNP denotes Background
T148 91-100 NNP denotes Activator
T149 101-108 NN denotes protein
T150 109-110 -LRB- denotes (
T151 110-112 NNP denotes AP
T152 112-113 -RRB- denotes )
T153 113-115 CD denotes -1
T154 116-119 CC denotes and
T155 120-127 JJ denotes nuclear
T156 128-134 NN denotes factor
T157 135-136 -LRB- denotes (
T158 136-138 NNP denotes NF
T159 138-139 -RRB- denotes )
T160 139-140 : denotes -
T161 140-142 NN denotes κB
T162 143-150 RB denotes largely
T163 151-158 JJ denotes control
T164 159-165 NNP denotes T-cell
T165 166-176 NN denotes activation
R57 T167 T139 prep following,regulation
R58 T168 T167 pobj binding,following
R59 T169 T168 prep of,binding
R60 T170 T171 amod foreign,antigens
R61 T171 T169 pobj antigens,of
R62 T172 T168 prep to,binding
R63 T173 T175 det the,receptor
R56 T166 T165 punct ",",activation
R64 T174 T175 compound T-cell,receptor
R65 T175 T172 pobj receptor,to
R66 T176 T175 acl leading,receptor
R67 T177 T176 prep to,leading
R68 T178 T179 amod cytokine,secretion
R69 T179 T177 pobj secretion,to
R70 T180 T139 punct .,regulation
R71 T181 T182 amod Elevated,levels
R72 T182 T196 nsubjpass levels,associated
R73 T183 T182 prep of,levels
R74 T184 T185 amod pro-inflammatory,cytokines
R75 T185 T183 pobj cytokines,of
R76 T186 T185 cc and,cytokines
R77 T187 T185 conj chemokines,cytokines
R78 T188 T189 amod such,as
R79 T189 T187 prep as,chemokines
R80 T190 T189 pobj TNF,as
R81 T191 T190 punct ",",TNF
R82 T192 T190 conj IL-6,TNF
R83 T193 T192 cc and,IL-6
R84 T194 T192 conj CXCL8,IL-6
R85 T195 T196 auxpass are,associated
R86 T196 T196 ROOT associated,associated
R87 T197 T196 prep with,associated
R88 T198 T200 amod several,diseases
R89 T199 T200 amod human,diseases
R90 T200 T197 pobj diseases,with
R91 T201 T200 prep including,diseases
R92 T202 T203 amod cystic,fibrosis
R93 T203 T201 pobj fibrosis,including
R94 T204 T203 punct ",",fibrosis
R95 T205 T206 amod pulmonary,fibrosis
R96 T206 T203 conj fibrosis,fibrosis
R97 T207 T206 cc and,fibrosis
R98 T208 T206 conj AIDS,fibrosis
R99 T209 T196 punct .,associated
R100 T210 T211 det The,aim
R101 T211 T215 nsubj aim,was
R102 T212 T211 prep of,aim
R103 T213 T214 det this,study
R104 T214 T212 pobj study,of
R105 T215 T215 ROOT was,was
R106 T216 T217 aux to,investigate
R107 T217 T215 xcomp investigate,was
R108 T218 T219 det the,role
R109 T219 T217 dobj role,investigate
R110 T220 T219 prep of,role
R111 T221 T223 det the,factors
R112 T222 T223 compound transcription,factors
R113 T223 T220 pobj factors,of
R114 T224 T219 punct ",",role
R115 T225 T233 nmod AP-1,regulation
R116 T226 T225 cc and,AP-1
R117 T227 T225 conj NF-κB,AP-1
R118 T228 T233 punct ",",regulation
R119 T229 T233 prep in,regulation
R120 T230 T229 pobj IL-6,in
R121 T231 T230 cc and,IL-6
R122 T232 T233 compound CXCL8,regulation
R123 T233 T217 dep regulation,investigate
R124 T234 T233 prep in,regulation
R962 T142 T141 cc and,NF-κB
R963 T143 T141 conj AP-1,NF-κB
R964 T144 T139 prep in,regulation
R965 T145 T149 compound Jurkat,protein
R966 T146 T149 compound T-cells,protein
R967 T147 T148 compound Background,Activator
R968 T148 T149 compound Activator,protein
R969 T149 T144 pobj protein,in
R970 T150 T151 punct (,AP
R971 T151 T149 appos AP,protein
R972 T152 T151 punct ),AP
R973 T153 T151 nummod -1,AP
R974 T154 T149 cc and,protein
R975 T155 T156 amod nuclear,factor
R976 T156 T149 conj factor,protein
R977 T157 T158 punct (,NF
R978 T158 T156 appos NF,factor
R979 T159 T158 punct ),NF
R980 T160 T161 punct -,κB
R981 T161 T165 amod κB,activation
R982 T162 T163 advmod largely,control
R983 T163 T165 amod control,activation
R984 T164 T165 compound T-cell,activation
R985 T165 T139 conj activation,regulation
R957 T137 T139 compound Differential,regulation
R958 T138 T139 compound cytokine,regulation
R959 T139 T139 ROOT regulation,regulation
R960 T140 T139 prep by,regulation
R961 T141 T140 pobj NF-κB,by

GO-BP

Id Subject Object Predicate Lexical cue
T969 22-32 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T970 572-582 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T978 159-176 http://purl.obolibrary.org/obo/GO_0051132 denotes T-cell activation
T979 159-176 http://purl.obolibrary.org/obo/GO_0042110 denotes T-cell activation
T980 159-176 http://purl.obolibrary.org/obo/GO_0050798 denotes T-cell activation
T981 159-176 http://purl.obolibrary.org/obo/GO_0050863 denotes T-cell activation
T982 159-176 http://purl.obolibrary.org/obo/GO_1903905 denotes T-cell activation
T983 161-176 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T984 250-268 http://purl.obolibrary.org/obo/GO_0050663 denotes cytokine secretion
T985 259-268 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T986 515-528 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription

GO-MF

Id Subject Object Predicate Lexical cue
T1003 188-195 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T1004 223-238 http://purl.obolibrary.org/obo/GO_0042608 denotes T-cell receptor
T1005 344-348 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6
T1006 557-561 http://purl.obolibrary.org/obo/GO_0005138 denotes IL-6

GO-CC

Id Subject Object Predicate Lexical cue
T1018 63-68 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T1021 223-238 http://purl.obolibrary.org/obo/GO_0042101 denotes T-cell receptor

sentences

Id Subject Object Predicate Lexical cue
T119 0-68 Sentence denotes Differential cytokine regulation by NF-κB and AP-1 in Jurkat T-cells
T120 80-90 Sentence denotes Background
T121 91-269 Sentence denotes Activator protein (AP)-1 and nuclear factor (NF)-κB largely control T-cell activation, following binding of foreign antigens to the T-cell receptor leading to cytokine secretion.
T122 270-457 Sentence denotes Elevated levels of pro-inflammatory cytokines and chemokines such as TNF, IL-6 and CXCL8 are associated with several human diseases including cystic fibrosis, pulmonary fibrosis and AIDS.
T1 0-68 Sentence denotes Differential cytokine regulation by NF-κB and AP-1 in Jurkat T-cells
T2 71-79 Sentence denotes Abstract
T3 80-90 Sentence denotes Background
T4 91-269 Sentence denotes Activator protein (AP)-1 and nuclear factor (NF)-κB largely control T-cell activation, following binding of foreign antigens to the T-cell receptor leading to cytokine secretion.
T5 270-457 Sentence denotes Elevated levels of pro-inflammatory cytokines and chemokines such as TNF, IL-6 and CXCL8 are associated with several human diseases including cystic fibrosis, pulmonary fibrosis and AIDS.

ICD10

Id Subject Object Predicate Lexical cue
T1002 412-438 http://purl.bioontology.org/ontology/ICD10/E84.0 denotes cystic fibrosis, pulmonary
T1000 412-427 http://purl.bioontology.org/ontology/ICD10/E84 denotes cystic fibrosis
T1001 412-427 http://purl.bioontology.org/ontology/ICD10/E84.9 denotes cystic fibrosis

events-check-again

Id Subject Object Predicate Lexical cue Negation
T1212 344-348 Protein denotes IL-6
T1213 353-358 Protein denotes CXCL8
T1214 503-507 Regulation denotes role true
T1215 503-507 Regulation denotes role true
T1216 557-561 Protein denotes IL-6
T1217 566-571 Protein denotes CXCL8
T1218 572-582 Regulation denotes regulation
T1219 572-582 Regulation denotes regulation
R877 T1216 T1219 themeOf IL-6,regulation
R878 T1217 T1218 themeOf CXCL8,regulation
R879 T1218 T1214 themeOf regulation,role
R880 T1219 T1215 themeOf regulation,role

bionlp-st-ge-2016-reference-tees

Id Subject Object Predicate Lexical cue
T1252 36-41 Protein denotes NF-κB
T1253 46-50 Protein denotes AP-1
T1254 140-142 Protein denotes κB
T1255 188-195 Binding denotes binding
T1256 339-342 Protein denotes TNF
T1257 344-348 Protein denotes IL-6
T1258 353-358 Protein denotes CXCL8
T1259 538-542 Protein denotes AP-1
T1260 547-552 Protein denotes NF-κB
T1261 557-561 Protein denotes IL-6
T1262 566-571 Protein denotes CXCL8
T1263 572-582 Regulation denotes regulation
T1264 572-582 Regulation denotes regulation
T1265 503-507 Regulation denotes role
T1266 503-507 Regulation denotes role
R898 T1254 T1255 themeOf κB,binding
R899 T1261 T1263 themeOf IL-6,regulation
R900 T1262 T1264 themeOf CXCL8,regulation
R901 T1263 T1265 themeOf regulation,role
R902 T1264 T1266 themeOf regulation,role

bionlp-st-ge-2016-reference

Id Subject Object Predicate Lexical cue Negation
T79 344-348 Protein denotes IL-6
T80 353-358 Protein denotes CXCL8
T81 503-507 Regulation denotes role true
T82 503-507 Regulation denotes role true
T83 557-561 Protein denotes IL-6
T84 566-571 Protein denotes CXCL8
T85 572-582 Regulation denotes regulation
T86 572-582 Regulation denotes regulation
R45 T83 T86 themeOf IL-6,regulation
R48 T86 T82 themeOf regulation,role
R46 T84 T85 themeOf CXCL8,regulation
R47 T85 T81 themeOf regulation,role

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T928 462-465 P26358 denotes aim
T929 538-542 P05412 denotes AP-1
T930 557-561 P05231 denotes IL-6
T931 566-571 P10145 denotes CXCL8
T924 46-50 P05412 denotes AP-1
T925 339-342 P01375 denotes TNF
T926 344-348 P05231 denotes IL-6
T927 353-358 P10145 denotes CXCL8

test2

Id Subject Object Predicate Lexical cue Negation
T41 344-348 Protein denotes IL-6 true
T42 353-358 Protein denotes CXCL8
T43 363-373 Binding denotes associated true
T44 503-507 Regulation denotes role
T45 557-561 Protein denotes IL-6
T46 566-571 Protein denotes CXCL8
T47 572-582 Regulation denotes regulation
R22 T41 T43 themeOf IL-6,associated
R23 T42 T43 themeOf CXCL8,associated
R24 T45 T47 themeOf IL-6,regulation
R25 T46 T47 themeOf CXCL8,regulation