PMC:2871132 / 222992-225008 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2871132","sourcedb":"PMC","sourceid":"2871132","source_url":"http://www.ncbi.nlm.nih.gov/pmc/2871132","text":"5.4. Fluoride Treatment\nIt is known in the literature that fluoride ions have osteopromoting capacity leading to increased calcification of the bone. Titanium fluoride is reported to form a stable layer on enamel surfaces consisting of titanium which share the oxygen atoms of phosphate on the surface of hydroxyapatite. Ellingsen et al. [394] investigated as to whether a similar, or rather reverse, reaction would take place on fluoride pre-treated titanium after implantation in bone. Threaded TiO2-blasted titanium implants were pre-conditioned with fluoride. The implants were operated into the tibia of Chinchilla rabbits and let to heal for two months before sacrificing the animals. The strength of the bonding between the implants and bones was tested by removing the implants from the bones by the use of an electronic removal torque gauge. It was reported that (i) the fluoride conditioned titanium implants had a significantly increased retention in bone (69.5 N-cm) compared to non-treated blasted implants (56.0 N-cm) and smooth surface implants (17.2 N-cm), and (ii) the histological evaluation revealed that new bones formed on the surface of the test implants, as well as in the marrow or cancellous regions, which was not observed in the control groups, suggesting that fluoride conditioning of titanium has an osteopromoting effect after implantation [394]. Furthermore, push-out tests of fluoridated and control Ti implants placed in rabbits for up to 8 weeks were conducted [395]. It was found that the fluoridated implants sustained greater push-out forces than the controls, and substantial bone adhesion was observed in fluoridated implants, whereas the controls always failed at the interface between the bone and foreign materials. In other rabbit test conducted by Ellingsen et al. [396], it was reported that the fluoridated, blasted implants showed a significantly higher removal torque than the blasted test implant, again indicative of a bioactive reaction of fluoridated Ti implants.","divisions":[{"label":"Title","span":{"begin":6,"end":24}}],"tracks":[]}