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PMC:2817507 / 82-1379 JSONTXT

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pmc-enju-pas

Id Subject Object Predicate Lexical cue
T383 1290-1296 NN denotes damage
T382 1284-1289 NN denotes brain
T381 1272-1283 JJ denotes ICH-induced
T380 1268-1271 IN denotes for
T379 1261-1267 NN denotes target
T378 1249-1260 JJ denotes therapeutic
T377 1247-1248 DT denotes a
T376 1240-1246 VB denotes become
T375 1236-1239 MD denotes may
T374 1230-1235 WDT denotes which
T373 1228-1229 -COMMA- denotes ,
T372 1225-1228 NN denotes ICH
T371 1222-1224 IN denotes of
T370 1209-1221 NN denotes pathogenesis
T369 1205-1208 DT denotes the
T368 1202-1204 IN denotes in
T367 1189-1201 VB denotes participates
T366 1179-1188 NN denotes signaling
T365 1174-1178 NN denotes NFκB
T364 1160-1173 JJ denotes TLR4-mediated
T363 1155-1159 IN denotes that
T362 1146-1154 VB denotes suggests
T361 1138-1145 RB denotes firstly
T360 1132-1137 NN denotes study
T359 1124-1131 JJ denotes present
T358 1120-1123 DT denotes The
T357 1111-1118 NN denotes control
T356 1104-1110 NN denotes saline
T355 1099-1103 IN denotes with
T335 999-1000 SYM denotes <
T334 997-998 NN denotes P
T333 996-997 -LRB- denotes (
T332 992-995 NN denotes ICH
T331 986-991 IN denotes after
T330 982-985 NN denotes day
T329 978-981 JJ denotes 7th
T328 974-977 DT denotes the
T327 971-973 IN denotes on
T326 965-970 NN denotes level
T325 958-964 JJ denotes higher
T324 956-957 DT denotes a
T323 953-955 IN denotes at
T322 942-952 VB denotes maintained
T321 936-941 RB denotes still
T320 932-935 CC denotes but
T319 922-931 VB denotes decreased
T318 917-921 RB denotes then
T317 913-916 CC denotes and
T316 911-912 -COMMA- denotes ,
T315 908-911 NN denotes ICH
T314 902-907 IN denotes after
T313 898-901 NN denotes day
T312 894-897 JJ denotes 3rd
T311 890-893 DT denotes the
T310 887-889 IN denotes on
T309 880-886 VB denotes peaked
T308 878-879 -COMMA- denotes ,
T307 875-878 NN denotes ICH
T306 869-874 IN denotes after
T305 861-868 NN denotes 6 hours
T304 858-860 IN denotes at
T303 849-857 VB denotes starting
T302 839-848 VB denotes increased
T301 825-838 RB denotes significantly
T300 817-824 NN denotes protein
T299 813-816 CC denotes and
T298 808-812 NN denotes mRNA
T297 803-807 NN denotes TLR4
T296 799-802 DT denotes the
T295 797-798 -COMMA- denotes ,
T294 790-797 NN denotes control
T293 783-789 NN denotes saline
T292 778-782 IN denotes with
T291 769-777 VB denotes Compared
T290 763-767 NN denotes EMSA
T289 759-762 CC denotes and
T288 757-758 -COMMA- denotes ,
T287 749-757 NN denotes staining
T286 728-748 NN denotes immunohistochemistry
T285 726-727 -COMMA- denotes ,
T284 721-726 NN denotes blots
T283 713-720 JJ denotes Western
T282 711-712 -COMMA- denotes ,
T281 705-711 NN denotes Rt-PCR
T280 702-704 IN denotes by
T279 695-701 NN denotes tissue
T278 686-694 JJ denotes cerebral
T277 674-685 JJ denotes hemorrhagic
T276 671-673 IN denotes in
T275 662-670 VB denotes examined
T274 657-661 VB denotes were
T273 652-656 NN denotes NFκB
T272 649-651 IN denotes of
T271 640-648 NN denotes activity
T270 636-639 DT denotes the
T269 632-635 CC denotes and
T268 630-631 -COMMA- denotes ,
T267 629-630 -RRB- denotes )
T266 623-629 NN denotes p-IκBα
T265 622-623 -LRB- denotes (
T264 620-621 NN denotes B
T263 614-619 NN denotes kappa
T262 611-613 IN denotes of
T261 600-610 NN denotes inhibitors
T260 597-599 IN denotes of
T259 581-596 NN denotes phosphorylation
T258 577-580 DT denotes the
T257 575-576 -COMMA- denotes ,
T256 568-575 NN denotes protein
T255 564-567 CC denotes and
T254 559-563 NN denotes mRNA
T253 554-558 NN denotes TLR4
T252 549-552 NN denotes ICH
T251 543-548 IN denotes after
T250 538-542 NN denotes rats
T249 531-537 NNP denotes Wistar
T248 528-530 IN denotes of
T247 520-527 NN denotes tissues
T246 514-519 NN denotes brain
T245 511-513 IN denotes in
T244 501-510 NN denotes signaling
T243 496-500 NN denotes NFκB
T242 482-495 JJ denotes TLR4-mediated
T241 479-481 IN denotes of
T240 468-478 NN denotes activation
T239 464-467 DT denotes the
T238 460-463 CC denotes and
T237 455-459 NN denotes TLR4
T236 452-454 IN denotes of
T235 441-451 NN denotes expression
T234 437-440 DT denotes the
T233 434-436 IN denotes of
T232 426-433 NN denotes profile
T231 417-425 JJ denotes temporal
T230 413-416 DT denotes the
T229 404-412 VB denotes evaluate
T228 401-403 TO denotes to
T227 397-400 VB denotes was
T226 391-396 NN denotes study
T225 383-390 JJ denotes present
T224 379-382 DT denotes The
T223 370-377 JJ denotes unknown
T222 362-369 VB denotes remains
T221 358-361 NN denotes ICH
T220 355-357 IN denotes of
T219 342-354 NN denotes pathogenesis
T218 338-341 DT denotes the
T217 335-337 IN denotes in
T216 325-334 NN denotes signaling
T215 320-324 NN denotes NFκB
T214 306-319 JJ denotes TLR4-mediated
T213 303-305 IN denotes of
T212 291-302 NN denotes involvement
T211 287-290 DT denotes the
T210 285-286 -COMMA- denotes ,
T209 278-285 RB denotes However
T208 271-276 NN denotes brain
T207 263-270 JJ denotes injured
T206 260-262 IN denotes in
T205 250-259 NN denotes responses
T204 237-249 JJ denotes inflammatory
T203 234-236 IN denotes of
T202 223-233 NN denotes regulation
T201 219-222 CC denotes and
T200 208-218 NN denotes activation
T199 204-207 DT denotes the
T198 201-203 IN denotes in
T197 195-200 NN denotes roles
T196 186-194 JJ denotes critical
T195 180-185 VB denotes plays
T194 170-179 NN denotes signaling
T193 168-169 -RRB- denotes )
T192 164-168 NN denotes NFκB
T191 163-164 -LRB- denotes (
T190 155-162 NN denotes kappa-B
T189 148-154 NN denotes factor
T188 140-147 JJ denotes nuclear
T187 131-139 VB denotes mediated
T186 129-130 -RRB- denotes )
T185 124-129 NN denotes TLR4-
T184 123-124 -LRB- denotes (
T183 120-122 NN denotes 4-
T182 111-119 NN denotes receptor
T181 101-110 JJ denotes Toll-like
T180 98-99 -RRB- denotes )
T179 95-98 NN denotes ICH
T178 94-95 -LRB- denotes (
T177 83-93 NN denotes hemorrhage
T176 69-82 JJ denotes Intracerebral
T175 66-68 IN denotes of
T174 53-65 NN denotes pathogenesis
T173 49-52 DT denotes the
T172 46-48 IN denotes in
T171 41-45 NN denotes role
T170 33-40 JJ denotes crucial
T169 31-32 DT denotes a
T168 26-30 VB denotes play
T167 17-25 NN denotes immunity
T166 13-16 CC denotes and
T165 0-12 NN denotes Inflammation
T354 1090-1098 VB denotes compared
T353 1086-1089 NN denotes ICH
T352 1080-1085 IN denotes after
T351 1074-1079 NN denotes brain
T350 1070-1073 DT denotes the
T349 1067-1069 IN denotes in
T348 1057-1066 VB denotes increased
T347 1052-1056 RB denotes also
T346 1047-1051 NN denotes NFκB
T345 1044-1046 IN denotes of
T344 1035-1043 NN denotes activity
T343 1031-1034 DT denotes the
T342 1027-1030 CC denotes and
T341 1020-1026 NN denotes p-IκBα
T340 1017-1019 IN denotes of
T339 1011-1016 NN denotes level
T338 1007-1010 DT denotes The
T337 1004-1005 -RRB- denotes )
T336 1001-1004 CD denotes .05
R34 T165 T166 arg1Of Inflammation,and
R35 T166 T168 arg1Of and,play
R36 T167 T166 arg2Of immunity,and
R37 T168 T172 arg1Of play,in
R38 T171 T168 arg2Of role,play
R39 T171 T169 arg1Of role,a
R40 T171 T170 arg1Of role,crucial
R41 T174 T172 arg2Of pathogenesis,in
R42 T174 T173 arg1Of pathogenesis,the
R43 T174 T175 arg1Of pathogenesis,of
R44 T177 T175 arg2Of hemorrhage,of
R45 T177 T176 arg1Of hemorrhage,Intracerebral
R46 T177 T178 arg1Of hemorrhage,(
R47 T179 T178 arg2Of ICH,(
R48 T180 T178 arg3Of ),(
R49 T183 T181 arg1Of 4-,Toll-like
R50 T183 T182 arg1Of 4-,receptor
R51 T183 T184 arg1Of 4-,(
R52 T185 T184 arg2Of TLR4-,(
R53 T186 T184 arg3Of ),(
R54 T192 T191 arg2Of NFκB,(
R55 T193 T191 arg3Of ),(
R56 T194 T183 arg1Of signaling,4-
R57 T194 T187 arg2Of signaling,mediated
R58 T194 T188 arg1Of signaling,nuclear
R59 T194 T189 arg1Of signaling,factor
R60 T194 T190 arg1Of signaling,kappa-B
R61 T194 T191 arg1Of signaling,(
R62 T194 T195 arg1Of signaling,plays
R63 T195 T198 arg1Of plays,in
R64 T197 T195 arg2Of roles,plays
R65 T197 T196 arg1Of roles,critical
R66 T200 T201 arg1Of activation,and
R67 T201 T198 arg2Of and,in
R68 T201 T199 arg1Of and,the
R69 T201 T203 arg1Of and,of
R70 T201 T206 arg1Of and,in
R71 T202 T201 arg2Of regulation,and
R72 T205 T203 arg2Of responses,of
R73 T205 T204 arg1Of responses,inflammatory
R74 T208 T206 arg2Of brain,in
R75 T208 T207 arg1Of brain,injured
R76 T212 T211 arg1Of involvement,the
R77 T212 T213 arg1Of involvement,of
R78 T212 T217 arg1Of involvement,in
R79 T212 T222 arg1Of involvement,remains
R80 T212 T223 arg1Of involvement,unknown
R81 T216 T213 arg2Of signaling,of
R82 T216 T214 arg1Of signaling,TLR4-mediated
R83 T216 T215 arg1Of signaling,NFκB
R84 T219 T217 arg2Of pathogenesis,in
R85 T219 T218 arg1Of pathogenesis,the
R86 T219 T220 arg1Of pathogenesis,of
R87 T221 T220 arg2Of ICH,of
R88 T222 T209 arg1Of remains,However
R89 T222 T210 arg1Of remains,","
R90 T223 T222 arg2Of unknown,remains
R91 T226 T224 arg1Of study,The
R92 T226 T225 arg1Of study,present
R93 T226 T227 arg1Of study,was
R94 T229 T227 arg2Of evaluate,was
R95 T229 T228 arg1Of evaluate,to
R96 T232 T230 arg1Of profile,the
R97 T232 T231 arg1Of profile,temporal
R98 T232 T233 arg1Of profile,of
R99 T232 T238 arg1Of profile,and
R100 T235 T233 arg2Of expression,of
R101 T235 T234 arg1Of expression,the
R102 T235 T236 arg1Of expression,of
R103 T237 T236 arg2Of TLR4,of
R104 T238 T229 arg2Of and,evaluate
R105 T240 T238 arg2Of activation,and
R106 T240 T239 arg1Of activation,the
R107 T240 T241 arg1Of activation,of
R108 T240 T245 arg1Of activation,in
R109 T244 T241 arg2Of signaling,of
R110 T244 T242 arg1Of signaling,TLR4-mediated
R111 T244 T243 arg1Of signaling,NFκB
R112 T247 T245 arg2Of tissues,in
R113 T247 T246 arg1Of tissues,brain
R114 T247 T248 arg1Of tissues,of
R115 T250 T248 arg2Of rats,of
R116 T250 T249 arg1Of rats,Wistar
R117 T250 T251 arg1Of rats,after
R118 T252 T251 arg2Of ICH,after
R119 T254 T255 arg1Of mRNA,and
R120 T255 T253 arg1Of and,TLR4
R121 T255 T257 arg1Of and,","
R122 T255 T269 arg1Of and,and
R123 T256 T255 arg2Of protein,and
R124 T259 T257 arg2Of phosphorylation,","
R125 T259 T258 arg1Of phosphorylation,the
R126 T259 T260 arg1Of phosphorylation,of
R127 T261 T260 arg2Of inhibitors,of
R128 T261 T262 arg1Of inhibitors,of
R129 T264 T262 arg2Of B,of
R130 T264 T263 arg1Of B,kappa
R131 T264 T265 arg1Of B,(
R132 T266 T265 arg2Of p-IκBα,(
R133 T267 T265 arg3Of ),(
R134 T269 T268 arg1Of and,","
R135 T269 T274 arg1Of and,were
R136 T269 T275 arg2Of and,examined
R137 T271 T269 arg2Of activity,and
R138 T271 T270 arg1Of activity,the
R139 T271 T272 arg1Of activity,of
R140 T273 T272 arg2Of NFκB,of
R141 T275 T274 arg2Of examined,were
R142 T275 T276 arg1Of examined,in
R143 T279 T276 arg2Of tissue,in
R144 T279 T277 arg1Of tissue,hemorrhagic
R145 T279 T278 arg1Of tissue,cerebral
R146 T281 T282 arg1Of Rt-PCR,","
R147 T282 T285 arg1Of ",",","
R148 T284 T282 arg2Of blots,","
R149 T284 T283 arg1Of blots,Western
R150 T285 T289 arg1Of ",",and
R151 T287 T285 arg2Of staining,","
R152 T287 T286 arg1Of staining,immunohistochemistry
R153 T289 T275 arg1Of and,examined
R154 T289 T280 arg2Of and,by
R155 T289 T288 arg1Of and,","
R156 T290 T289 arg2Of EMSA,and
R157 T292 T291 arg2Of with,Compared
R158 T294 T292 arg2Of control,with
R159 T294 T293 arg1Of control,saline
R160 T298 T297 arg1Of mRNA,TLR4
R161 T298 T299 arg1Of mRNA,and
R162 T299 T296 arg1Of and,the
R163 T299 T302 arg1Of and,increased
R164 T299 T309 arg1Of and,peaked
R165 T299 T319 arg1Of and,decreased
R166 T299 T322 arg2Of and,maintained
R167 T300 T299 arg2Of protein,and
R168 T302 T308 arg1Of increased,","
R169 T303 T302 arg2Of starting,increased
R170 T303 T304 arg1Of starting,at
R171 T303 T306 arg1Of starting,after
R172 T305 T304 arg2Of 6 hours,at
R173 T307 T306 arg2Of ICH,after
R174 T308 T317 arg1Of ",",and
R175 T309 T308 arg2Of peaked,","
R176 T309 T310 arg1Of peaked,on
R177 T313 T310 arg2Of day,on
R178 T313 T311 arg1Of day,the
R179 T313 T312 arg1Of day,3rd
R180 T313 T314 arg1Of day,after
R181 T315 T314 arg2Of ICH,after
R182 T317 T291 arg1Of and,Compared
R183 T317 T295 arg1Of and,","
R184 T317 T301 arg1Of and,significantly
R185 T317 T316 arg1Of and,","
R186 T319 T320 arg1Of decreased,but
R187 T320 T317 arg2Of but,and
R188 T320 T318 arg1Of but,then
R189 T322 T320 arg2Of maintained,but
R190 T322 T321 arg1Of maintained,still
R191 T322 T323 arg1Of maintained,at
R192 T322 T327 arg1Of maintained,on
R193 T322 T331 arg1Of maintained,after
R194 T326 T323 arg2Of level,at
R195 T326 T324 arg1Of level,a
R196 T326 T325 arg1Of level,higher
R197 T330 T327 arg2Of day,on
R198 T330 T328 arg1Of day,the
R199 T330 T329 arg1Of day,7th
R200 T332 T331 arg2Of ICH,after
R201 T332 T333 arg1Of ICH,(
R202 T334 T333 arg2Of P,(
R203 T334 T335 arg1Of P,<
R204 T335 T336 arg1Of <,.05
R205 T337 T333 arg3Of ),(
R206 T339 T338 arg1Of level,The
R207 T339 T340 arg1Of level,of
R208 T339 T342 arg1Of level,and
R209 T341 T340 arg2Of p-IκBα,of
R210 T342 T348 arg1Of and,increased
R211 T344 T342 arg2Of activity,and
R212 T344 T343 arg1Of activity,the
R213 T344 T345 arg1Of activity,of
R214 T346 T345 arg2Of NFκB,of
R215 T348 T347 arg1Of increased,also
R216 T348 T349 arg1Of increased,in
R217 T348 T352 arg1Of increased,after
R218 T351 T349 arg2Of brain,in
R219 T351 T350 arg1Of brain,the
R220 T353 T352 arg2Of ICH,after
R221 T353 T354 arg1Of ICH,compared
R222 T355 T354 arg2Of with,compared
R223 T357 T355 arg2Of control,with
R224 T357 T356 arg1Of control,saline
R225 T360 T358 arg1Of study,The
R226 T360 T359 arg1Of study,present
R227 T360 T362 arg1Of study,suggests
R228 T362 T361 arg1Of suggests,firstly
R229 T366 T364 arg1Of signaling,TLR4-mediated
R230 T366 T365 arg1Of signaling,NFκB
R231 T366 T367 arg1Of signaling,participates
R232 T367 T362 arg2Of participates,suggests
R233 T367 T363 arg1Of participates,that
R234 T367 T368 arg1Of participates,in
R235 T370 T368 arg2Of pathogenesis,in
R236 T370 T369 arg1Of pathogenesis,the
R237 T370 T371 arg1Of pathogenesis,of
R238 T370 T373 arg1Of pathogenesis,","
R239 T370 T374 arg1Of pathogenesis,which
R240 T370 T375 arg1Of pathogenesis,may
R241 T370 T376 arg1Of pathogenesis,become
R242 T372 T371 arg2Of ICH,of
R243 T376 T375 arg2Of become,may
R244 T379 T376 arg2Of target,become
R245 T379 T377 arg1Of target,a
R246 T379 T378 arg1Of target,therapeutic
R247 T379 T380 arg1Of target,for
R248 T383 T380 arg2Of damage,for
R249 T383 T381 arg1Of damage,ICH-induced
R250 T383 T382 arg1Of damage,brain

bionlp-st-ge-2016-test-proteins

Id Subject Object Predicate Lexical cue
T91 101-121 Protein denotes Toll-like receptor 4
T92 124-128 Protein denotes TLR4
T93 306-310 Protein denotes TLR4
T94 455-459 Protein denotes TLR4
T95 482-486 Protein denotes TLR4
T96 554-558 Protein denotes TLR4
T97 600-621 Protein denotes inhibitors of kappa B
T98 625-629 Protein denotes IκBα
T99 803-807 Protein denotes TLR4
T100 1022-1026 Protein denotes IκBα
T101 1160-1164 Protein denotes TLR4

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T625 124-128 http://www.uniprot.org/uniprot/O00206 denotes TLR4
T626 306-310 http://www.uniprot.org/uniprot/O00206 denotes TLR4
T627 455-459 http://www.uniprot.org/uniprot/O00206 denotes TLR4
T628 482-486 http://www.uniprot.org/uniprot/O00206 denotes TLR4
T629 554-558 http://www.uniprot.org/uniprot/O00206 denotes TLR4
T630 803-807 http://www.uniprot.org/uniprot/O00206 denotes TLR4
T631 1160-1164 http://www.uniprot.org/uniprot/O00206 denotes TLR4

UBERON-AE

Id Subject Object Predicate Lexical cue
T62 695-701 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue
T61 520-527 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissues
T60 1284-1289 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T59 1074-1079 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T58 514-519 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T57 271-276 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain

GO-BP

Id Subject Object Predicate Lexical cue
T102 0-12 http://purl.obolibrary.org/obo/GO_0006954 denotes Inflammation
T103 237-259 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory responses
T104 53-65 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T105 342-354 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T106 1209-1221 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T107 170-179 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T108 325-334 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T109 501-510 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T110 1179-1188 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T111 223-233 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T112 223-259 http://purl.obolibrary.org/obo/GO_0002676 denotes regulation of inflammatory responses
T113 223-259 http://purl.obolibrary.org/obo/GO_0050729 denotes regulation of inflammatory responses
T114 223-259 http://purl.obolibrary.org/obo/GO_0050727 denotes regulation of inflammatory responses
T115 223-259 http://purl.obolibrary.org/obo/GO_0050728 denotes regulation of inflammatory responses
T116 223-259 http://purl.obolibrary.org/obo/GO_0002673 denotes regulation of inflammatory responses
T117 568-596 http://purl.obolibrary.org/obo/GO_0006468 denotes protein, the phosphorylation
T118 581-596 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation

sentences

Id Subject Object Predicate Lexical cue
T71 1120-1297 Sentence denotes The present study firstly suggests that TLR4-mediated NFκB signaling participates in the pathogenesis of ICH, which may become a therapeutic target for ICH-induced brain damage.
T70 1007-1119 Sentence denotes The level of p-IκBα and the activity of NFκB also increased in the brain after ICH compared with saline control.
T69 769-1006 Sentence denotes Compared with saline control, the TLR4 mRNA and protein significantly increased starting at 6 hours after ICH, peaked on the 3rd day after ICH, and then decreased but still maintained at a higher level on the 7th day after ICH (P < .05).
T64 0-100 Sentence denotes Inflammation and immunity play a crucial role in the pathogenesis of Intracerebral hemorrhage (ICH).
T65 101-277 Sentence denotes Toll-like receptor 4- (TLR4-) mediated nuclear factor kappa-B (NFκB) signaling plays critical roles in the activation and regulation of inflammatory responses in injured brain.
T66 278-378 Sentence denotes However, the involvement of TLR4-mediated NFκB signaling in the pathogenesis of ICH remains unknown.
T67 379-553 Sentence denotes The present study was to evaluate the temporal profile of the expression of TLR4 and the activation of TLR4-mediated NFκB signaling in brain tissues of Wistar rats after ICH.
T68 554-768 Sentence denotes TLR4 mRNA and protein, the phosphorylation of inhibitors of kappa B (p-IκBα), and the activity of NFκB were examined in hemorrhagic cerebral tissue by Rt-PCR, Western blots, immunohistochemistry staining, and EMSA.
T3 0-100 Sentence denotes Inflammation and immunity play a crucial role in the pathogenesis of Intracerebral hemorrhage (ICH).
T4 101-277 Sentence denotes Toll-like receptor 4- (TLR4-) mediated nuclear factor kappa-B (NFκB) signaling plays critical roles in the activation and regulation of inflammatory responses in injured brain.
T5 278-378 Sentence denotes However, the involvement of TLR4-mediated NFκB signaling in the pathogenesis of ICH remains unknown.
T6 379-553 Sentence denotes The present study was to evaluate the temporal profile of the expression of TLR4 and the activation of TLR4-mediated NFκB signaling in brain tissues of Wistar rats after ICH.
T7 554-768 Sentence denotes TLR4 mRNA and protein, the phosphorylation of inhibitors of kappa B (p-IκBα), and the activity of NFκB were examined in hemorrhagic cerebral tissue by Rt-PCR, Western blots, immunohistochemistry staining, and EMSA.
T8 769-1006 Sentence denotes Compared with saline control, the TLR4 mRNA and protein significantly increased starting at 6 hours after ICH, peaked on the 3rd day after ICH, and then decreased but still maintained at a higher level on the 7th day after ICH (P < .05).
T9 1007-1119 Sentence denotes The level of p-IκBα and the activity of NFκB also increased in the brain after ICH compared with saline control.
T10 1120-1297 Sentence denotes The present study firstly suggests that TLR4-mediated NFκB signaling participates in the pathogenesis of ICH, which may become a therapeutic target for ICH-induced brain damage.

simple1

Id Subject Object Predicate Lexical cue
T154 1160-1164 Protein denotes TLR4
T153 1022-1026 Protein denotes IκBα
T152 803-807 Protein denotes TLR4
T151 625-629 Protein denotes IκBα
T150 600-621 Protein denotes inhibitors of kappa B
T149 554-558 Protein denotes TLR4
T148 482-486 Protein denotes TLR4
T147 455-459 Protein denotes TLR4
T146 306-310 Protein denotes TLR4
T145 124-128 Protein denotes TLR4
T144 101-121 Protein denotes Toll-like receptor 4

BioNLP16_DUT

Id Subject Object Predicate Lexical cue
T738 1057-1066 Positive_regulation denotes increased
T737 839-848 Positive_regulation denotes increased
T736 922-931 Negative_regulation denotes decreased
T735 942-952 Positive_regulation denotes maintained
T734 581-596 Phosphorylation denotes phosphorylation
T733 441-451 Gene_expression denotes expression
T732 1160-1164 Protein denotes TLR4
T731 1022-1026 Protein denotes IκBα
T730 803-807 Protein denotes TLR4
T729 625-629 Protein denotes IκBα
T728 600-621 Protein denotes inhibitors of kappa B
T727 554-558 Protein denotes TLR4
T726 482-486 Protein denotes TLR4
T725 455-459 Protein denotes TLR4
T724 306-310 Protein denotes TLR4
T723 124-128 Protein denotes TLR4
T722 101-121 Protein denotes Toll-like receptor 4
R509 T725 T733 themeOf TLR4,expression
R510 T727 T734 themeOf TLR4,phosphorylation
R511 T728 T734 themeOf inhibitors of kappa B,phosphorylation
R512 T730 T737 themeOf TLR4,increased
R513 T730 T736 themeOf TLR4,decreased
R514 T730 T735 themeOf TLR4,maintained
R515 T731 T738 themeOf IκBα,increased

BioNLP16_Messiy

Id Subject Object Predicate Lexical cue
T633 101-121 Protein denotes Toll-like receptor 4
T634 124-128 Protein denotes TLR4
T635 306-310 Protein denotes TLR4
T636 455-459 Protein denotes TLR4
T637 482-486 Protein denotes TLR4
T638 554-558 Protein denotes TLR4
T639 600-621 Protein denotes inhibitors of kappa B
T640 625-629 Protein denotes IκBα
T641 803-807 Protein denotes TLR4
T642 1022-1026 Protein denotes IκBα
T643 1160-1164 Protein denotes TLR4
T645 441-451 Gene_expression denotes expression
T646 581-596 Phosphorylation denotes phosphorylation
T647 922-931 Negative_regulation denotes decreased
T648 942-952 Positive_regulation denotes maintained
T649 839-848 Positive_regulation denotes increased
R529 T636 T645 themeOf TLR4,expression
R530 T638 T646 themeOf TLR4,phosphorylation
R531 T639 T646 themeOf inhibitors of kappa B,phosphorylation
R532 T641 T647 themeOf TLR4,decreased
R533 T641 T648 themeOf TLR4,maintained
R534 T641 T649 themeOf TLR4,increased

DLUT931

Id Subject Object Predicate Lexical cue
T696 1165-1173 Positive_regulation denotes mediated
T695 1057-1066 Positive_regulation denotes increased
T694 942-952 Positive_regulation denotes maintained
T693 922-931 Negative_regulation denotes decreased
T690 581-596 Phosphorylation denotes phosphorylation
T689 441-451 Gene_expression denotes expression
T688 1160-1164 Protein denotes TLR4
T687 1022-1026 Protein denotes IκBα
T686 803-807 Protein denotes TLR4
T685 625-629 Protein denotes IκBα
T684 600-621 Protein denotes inhibitors of kappa B
T683 554-558 Protein denotes TLR4
T682 482-486 Protein denotes TLR4
T681 455-459 Protein denotes TLR4
T680 306-310 Protein denotes TLR4
T679 124-128 Protein denotes TLR4
T678 101-121 Protein denotes Toll-like receptor 4
T691 839-848 Positive_regulation denotes increased
T692 880-886 Positive_regulation denotes peaked
R491 T681 T689 themeOf TLR4,expression
R492 T683 T690 themeOf TLR4,phosphorylation
R493 T684 T690 themeOf inhibitors of kappa B,phosphorylation
R494 T685 T690 themeOf IκBα,phosphorylation
R495 T686 T691 themeOf TLR4,increased
R496 T686 T692 themeOf TLR4,peaked
R497 T686 T693 themeOf TLR4,decreased
R498 T686 T694 themeOf TLR4,maintained
R499 T687 T695 themeOf IκBα,increased
R500 T688 T696 themeOf TLR4,mediated

bionlp-st-ge-2016-test-ihmc

Id Subject Object Predicate Lexical cue
T776 1165-1188 Regulation denotes mediated NFκB signaling
T774 306-334 Positive_regulation denotes TLR4-mediated NFκB signaling
T772 1165-1188 Positive_regulation denotes mediated NFκB signaling
T771 479-542 Positive_regulation denotes of TLR4-mediated NFκB signaling in brain tissues of Wistar rats
T770 306-334 Regulation denotes TLR4-mediated NFκB signaling
T769 479-542 Regulation denotes of TLR4-mediated NFκB signaling in brain tissues of Wistar rats
T768 799-874 Positive_regulation denotes the TLR4 mRNA and protein significantly increased starting at 6 hours after
T767 799-874 Positive_regulation denotes the TLR4 mRNA and protein significantly increased starting at 6 hours after
T766 437-459 Gene_expression denotes the expression of TLR4
T765 1155-1164 Protein denotes that TLR4
T764 649-656 Protein denotes of NFκB
T762 452-459 Protein denotes of TLR4
T761 1104-1110 Entity denotes saline
T760 306-319 Protein denotes TLR4-mediated
T759 708-711 Protein denotes PCR
T758 623-629 Protein denotes p-IκBα
T757 978-981 Entity denotes 7th
T756 817-824 Protein denotes protein
T755 997-998 Entity denotes P
T754 568-575 Protein denotes protein
T753 164-168 Protein denotes NFκB
T752 600-631 Protein denotes inhibitors of kappa B (p-IκBα),
T751 482-495 Protein denotes TLR4-mediated
T749 783-789 Entity denotes saline
T748 799-812 Protein denotes the TLR4 mRNA
T747 554-558 Protein denotes TLR4
T746 1020-1026 Protein denotes p-IκBα
T745 803-807 Protein denotes TLR4
T744 101-130 Protein denotes Toll-like receptor 4- (TLR4-)
T743 1174-1178 Protein denotes NFκB
T739 1044-1051 Protein denotes of NFκB
T740 496-500 Protein denotes NFκB
T741 320-324 Protein denotes NFκB
T742 554-563 Protein denotes TLR4 mRNA
R516 T743 T772 causeOf NFκB,mediated NFκB signaling
R517 T748 T768 causeOf the TLR4 mRNA,the TLR4 mRNA and protein significantly increased starting at 6 hours after
R519 T751 T769 causeOf TLR4-mediated,of TLR4-mediated NFκB signaling in brain tissues of Wistar rats
R520 T756 T767 causeOf protein,the TLR4 mRNA and protein significantly increased starting at 6 hours after
R521 T760 T770 causeOf TLR4-mediated,TLR4-mediated NFκB signaling
R522 T762 T766 themeOf of TLR4,the expression of TLR4
R524 T771 T769 themeOf of TLR4-mediated NFκB signaling in brain tissues of Wistar rats,of TLR4-mediated NFκB signaling in brain tissues of Wistar rats
R525 T772 T776 themeOf mediated NFκB signaling,mediated NFκB signaling
R526 T774 T770 themeOf TLR4-mediated NFκB signaling,TLR4-mediated NFκB signaling
R540 T740 T771 causeOf NFκB,of TLR4-mediated NFκB signaling in brain tissues of Wistar rats
R541 T741 T774 causeOf NFκB,TLR4-mediated NFκB signaling

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T570 996-997 -LRB- denotes (
T569 992-995 NNP denotes ICH
T568 986-991 IN denotes after
T567 982-985 NN denotes day
T566 978-981 JJ denotes 7th
T565 974-977 DT denotes the
T564 971-973 IN denotes on
T563 965-970 NN denotes level
T562 958-964 JJR denotes higher
T561 956-957 DT denotes a
T560 953-955 IN denotes at
T559 942-952 VBN denotes maintained
T558 936-941 RB denotes still
T557 932-935 CC denotes but
T556 922-931 VBD denotes decreased
T555 917-921 RB denotes then
T554 913-916 CC denotes and
T553 911-912 , denotes ,
T552 908-911 NNP denotes ICH
T551 902-907 IN denotes after
T550 898-901 NN denotes day
T549 894-897 JJ denotes 3rd
T548 890-893 DT denotes the
T547 887-889 IN denotes on
T546 880-886 VBD denotes peaked
T545 878-879 , denotes ,
T544 875-878 NNP denotes ICH
T543 869-874 IN denotes after
T542 863-868 NNS denotes hours
T541 861-862 CD denotes 6
T540 858-860 IN denotes at
T539 849-857 VBG denotes starting
T538 839-848 VBD denotes increased
T537 825-838 RB denotes significantly
T536 817-824 NN denotes protein
T535 813-816 CC denotes and
T534 808-812 NNP denotes mRNA
T533 803-807 CD denotes TLR4
T532 799-802 DT denotes the
T531 797-798 , denotes ,
T530 790-797 NN denotes control
T529 783-789 NN denotes saline
T528 778-782 IN denotes with
T527 769-777 VBN denotes Compared
T526 767-768 . denotes .
T525 763-767 NNP denotes EMSA
T524 759-762 CC denotes and
T523 757-758 , denotes ,
T522 749-757 NN denotes staining
T521 728-748 NN denotes immunohistochemistry
T520 726-727 , denotes ,
T519 721-726 NNS denotes blots
T518 713-720 NNP denotes Western
T517 711-712 , denotes ,
T516 705-711 NNP denotes Rt-PCR
T515 702-704 IN denotes by
T514 695-701 NN denotes tissue
T513 686-694 JJ denotes cerebral
T512 674-685 JJ denotes hemorrhagic
T511 671-673 IN denotes in
T510 662-670 VBN denotes examined
T509 657-661 VBD denotes were
T508 652-656 NNP denotes NFκB
T507 649-651 IN denotes of
T506 640-648 NN denotes activity
T505 636-639 DT denotes the
T504 632-635 CC denotes and
T503 630-631 , denotes ,
T502 629-630 -RRB- denotes )
T501 623-629 NNP denotes p-IκBα
T500 622-623 -LRB- denotes (
T499 620-621 NNP denotes B
T498 614-619 NN denotes kappa
T497 611-613 IN denotes of
T496 600-610 NNS denotes inhibitors
T495 597-599 IN denotes of
T494 581-596 NN denotes phosphorylation
T493 577-580 DT denotes the
T492 575-576 , denotes ,
T491 568-575 NN denotes protein
T490 564-567 CC denotes and
T489 559-563 NNP denotes mRNA
T488 554-558 CD denotes TLR4
T487 552-553 . denotes .
T486 549-552 NNP denotes ICH
T485 543-548 IN denotes after
T484 538-542 NNS denotes rats
T483 531-537 NNP denotes Wistar
T482 528-530 IN denotes of
T481 520-527 NNS denotes tissues
T480 514-519 NN denotes brain
T479 511-513 IN denotes in
T478 501-510 VBG denotes signaling
T477 496-500 NNP denotes NFκB
T476 482-495 JJ denotes TLR4-mediated
T475 479-481 IN denotes of
T474 468-478 NN denotes activation
T473 464-467 DT denotes the
T472 460-463 CC denotes and
T471 455-459 CD denotes TLR4
T470 452-454 IN denotes of
T469 441-451 NN denotes expression
T468 437-440 DT denotes the
T467 434-436 IN denotes of
T466 426-433 NN denotes profile
T465 417-425 JJ denotes temporal
T464 413-416 DT denotes the
T463 404-412 VB denotes evaluate
T462 401-403 TO denotes to
T461 397-400 VBD denotes was
T460 391-396 NN denotes study
T459 383-390 JJ denotes present
T458 379-382 DT denotes The
T457 377-378 . denotes .
T456 370-377 JJ denotes unknown
T455 362-369 VBZ denotes remains
T454 358-361 NNP denotes ICH
T453 355-357 IN denotes of
T452 342-354 NN denotes pathogenesis
T451 338-341 DT denotes the
T450 335-337 IN denotes in
T449 325-334 VBG denotes signaling
T448 320-324 NNP denotes NFκB
T447 306-319 JJ denotes TLR4-mediated
T446 303-305 IN denotes of
T445 291-302 NN denotes involvement
T444 287-290 DT denotes the
T443 285-286 , denotes ,
T442 278-285 RB denotes However
T441 276-277 . denotes .
T440 271-276 NN denotes brain
T439 263-270 JJ denotes injured
T438 260-262 IN denotes in
T437 250-259 NNS denotes responses
T436 237-249 JJ denotes inflammatory
T435 234-236 IN denotes of
T434 223-233 NN denotes regulation
T433 219-222 CC denotes and
T432 208-218 NN denotes activation
T431 204-207 DT denotes the
T430 201-203 IN denotes in
T429 195-200 NNS denotes roles
T428 186-194 JJ denotes critical
T427 180-185 NNS denotes plays
T426 170-179 VBG denotes signaling
T425 168-169 -RRB- denotes )
T424 164-168 NNP denotes NFκB
T423 163-164 -LRB- denotes (
T422 155-162 NN denotes kappa-B
T421 148-154 NN denotes factor
T420 140-147 JJ denotes nuclear
T419 131-139 VBN denotes mediated
T418 129-130 -RRB- denotes )
T417 128-129 : denotes -
T416 124-128 SYM denotes TLR4
T415 123-124 -LRB- denotes (
T414 121-122 : denotes -
T413 120-121 LS denotes 4
T412 111-119 NN denotes receptor
T411 101-110 JJ denotes Toll-like
T410 99-100 . denotes .
T409 98-99 -RRB- denotes )
T408 95-98 NNP denotes ICH
T407 94-95 -LRB- denotes (
T406 83-93 NN denotes hemorrhage
T405 69-82 NNP denotes Intracerebral
T404 66-68 IN denotes of
T403 53-65 NN denotes pathogenesis
T402 49-52 DT denotes the
T401 46-48 IN denotes in
T400 41-45 NN denotes role
T399 33-40 JJ denotes crucial
T398 31-32 DT denotes a
T397 26-30 VBP denotes play
T396 17-25 NN denotes immunity
T395 13-16 CC denotes and
T394 0-12 NNP denotes Inflammation
T623 1296-1297 . denotes .
T622 1290-1296 NN denotes damage
T621 1284-1289 NN denotes brain
T620 1272-1283 JJ denotes ICH-induced
T619 1268-1271 IN denotes for
T618 1261-1267 NN denotes target
T617 1249-1260 JJ denotes therapeutic
T616 1247-1248 DT denotes a
T615 1240-1246 VB denotes become
T614 1236-1239 MD denotes may
T613 1230-1235 WDT denotes which
T612 1228-1229 , denotes ,
T611 1225-1228 NNP denotes ICH
T610 1222-1224 IN denotes of
T609 1209-1221 NN denotes pathogenesis
T608 1205-1208 DT denotes the
T607 1202-1204 IN denotes in
T606 1189-1201 VBZ denotes participates
T605 1179-1188 VBG denotes signaling
T604 1174-1178 NNP denotes NFκB
T603 1160-1173 JJ denotes TLR4-mediated
T602 1155-1159 IN denotes that
T601 1146-1154 VBZ denotes suggests
T600 1138-1145 RB denotes firstly
T599 1132-1137 NN denotes study
T598 1124-1131 JJ denotes present
T597 1120-1123 DT denotes The
T596 1118-1119 . denotes .
T595 1111-1118 NN denotes control
T594 1104-1110 NN denotes saline
T593 1099-1103 IN denotes with
T592 1090-1098 VBN denotes compared
T591 1086-1089 NNP denotes ICH
T590 1080-1085 IN denotes after
T589 1074-1079 NN denotes brain
T588 1070-1073 DT denotes the
T587 1067-1069 IN denotes in
T586 1057-1066 VBD denotes increased
T585 1052-1056 RB denotes also
T584 1047-1051 NNP denotes NFκB
T583 1044-1046 IN denotes of
T582 1035-1043 NN denotes activity
T581 1031-1034 DT denotes the
T580 1027-1030 CC denotes and
T579 1020-1026 NNP denotes p-IκBα
T578 1017-1019 IN denotes of
T577 1011-1016 NN denotes level
T576 1007-1010 DT denotes The
T575 1005-1006 . denotes .
T574 1004-1005 -RRB- denotes )
T573 1001-1004 CD denotes .05
T572 999-1000 CD denotes <
T571 997-998 NNP denotes P
R263 T396 T397 nsubj immunity,play
R265 T398 T400 det a,role
R266 T399 T400 amod crucial,role
R267 T400 T397 dobj role,play
R268 T401 T397 prep in,play
R269 T402 T403 det the,pathogenesis
R270 T403 T401 pobj pathogenesis,in
R271 T404 T403 prep of,pathogenesis
R272 T405 T406 compound Intracerebral,hemorrhage
R273 T406 T404 pobj hemorrhage,of
R274 T407 T408 punct (,ICH
R275 T408 T406 appos ICH,hemorrhage
R278 T411 T412 amod Toll-like,receptor
R279 T412 T412 ROOT receptor,receptor
R280 T413 T419 meta 4,mediated
R281 T414 T413 punct -,4
R282 T415 T419 punct (,mediated
R283 T416 T419 ccomp TLR4,mediated
R284 T417 T416 punct -,TLR4
R285 T418 T419 punct ),mediated
R286 T419 T422 amod mediated,kappa-B
R287 T420 T421 amod nuclear,factor
R288 T421 T422 compound factor,kappa-B
R289 T422 T412 appos kappa-B,receptor
R290 T423 T422 punct (,kappa-B
R291 T424 T422 appos NFκB,kappa-B
R292 T425 T422 punct ),kappa-B
R293 T426 T412 acl signaling,receptor
R294 T427 T426 dobj plays,signaling
R295 T428 T429 amod critical,roles
R296 T429 T427 dobj roles,plays
R297 T430 T427 prep in,plays
R298 T431 T432 det the,activation
R299 T432 T430 pobj activation,in
R300 T433 T432 cc and,activation
R301 T434 T432 conj regulation,activation
R302 T435 T434 prep of,regulation
R303 T436 T437 amod inflammatory,responses
R304 T437 T435 pobj responses,of
R305 T438 T437 prep in,responses
R306 T439 T440 amod injured,brain
R307 T440 T438 pobj brain,in
R308 T441 T412 punct .,receptor
R309 T442 T455 advmod However,remains
R310 T443 T455 punct ",",remains
R311 T444 T445 det the,involvement
R312 T445 T455 nsubj involvement,remains
R313 T446 T445 prep of,involvement
R314 T447 T448 compound TLR4-mediated,NFκB
R315 T448 T446 pobj NFκB,of
R316 T449 T445 acl signaling,involvement
R317 T450 T449 prep in,signaling
R318 T451 T452 det the,pathogenesis
R319 T452 T450 pobj pathogenesis,in
R320 T453 T452 prep of,pathogenesis
R321 T454 T453 pobj ICH,of
R322 T455 T455 ROOT remains,remains
R323 T456 T455 acomp unknown,remains
R324 T457 T455 punct .,remains
R325 T458 T460 det The,study
R326 T459 T460 amod present,study
R327 T460 T461 nsubj study,was
R328 T461 T461 ROOT was,was
R329 T462 T463 aux to,evaluate
R330 T463 T461 xcomp evaluate,was
R331 T464 T466 det the,profile
R332 T465 T466 amod temporal,profile
R333 T466 T463 dobj profile,evaluate
R334 T467 T466 prep of,profile
R335 T468 T469 det the,expression
R336 T469 T467 pobj expression,of
R337 T470 T469 prep of,expression
R338 T471 T470 pobj TLR4,of
R339 T472 T469 cc and,expression
R340 T473 T474 det the,activation
R341 T474 T469 conj activation,expression
R342 T475 T474 prep of,activation
R343 T476 T477 compound TLR4-mediated,NFκB
R344 T477 T475 pobj NFκB,of
R345 T478 T466 acl signaling,profile
R346 T479 T478 prep in,signaling
R347 T480 T481 compound brain,tissues
R348 T481 T479 pobj tissues,in
R349 T482 T481 prep of,tissues
R350 T483 T484 compound Wistar,rats
R351 T484 T482 pobj rats,of
R352 T485 T463 prep after,evaluate
R353 T486 T485 pobj ICH,after
R354 T487 T461 punct .,was
R355 T488 T489 nummod TLR4,mRNA
R356 T489 T510 nsubjpass mRNA,examined
R357 T490 T489 cc and,mRNA
R358 T491 T489 conj protein,mRNA
R359 T492 T491 punct ",",protein
R360 T493 T494 det the,phosphorylation
R361 T494 T491 appos phosphorylation,protein
R362 T495 T494 prep of,phosphorylation
R363 T496 T495 pobj inhibitors,of
R364 T497 T496 prep of,inhibitors
R365 T498 T499 compound kappa,B
R366 T499 T497 pobj B,of
R367 T500 T499 punct (,B
R368 T501 T499 appos p-IκBα,B
R369 T502 T499 punct ),B
R370 T503 T494 punct ",",phosphorylation
R371 T504 T494 cc and,phosphorylation
R372 T505 T506 det the,activity
R373 T506 T494 conj activity,phosphorylation
R374 T507 T506 prep of,activity
R375 T508 T507 pobj NFκB,of
R376 T509 T510 auxpass were,examined
R377 T510 T510 ROOT examined,examined
R378 T511 T510 prep in,examined
R379 T512 T514 amod hemorrhagic,tissue
R380 T513 T514 amod cerebral,tissue
R381 T514 T511 pobj tissue,in
R382 T515 T510 agent by,examined
R383 T516 T515 pobj Rt-PCR,by
R384 T517 T516 punct ",",Rt-PCR
R385 T518 T519 amod Western,blots
R386 T519 T510 npadvmod blots,examined
R387 T520 T519 punct ",",blots
R388 T521 T522 compound immunohistochemistry,staining
R389 T522 T519 conj staining,blots
R390 T523 T522 punct ",",staining
R391 T524 T522 cc and,staining
R392 T525 T522 conj EMSA,staining
R393 T526 T510 punct .,examined
R394 T527 T538 prep Compared,increased
R395 T528 T527 prep with,Compared
R396 T529 T530 compound saline,control
R397 T530 T528 pobj control,with
R398 T531 T530 punct ",",control
R399 T532 T534 det the,mRNA
R400 T533 T534 nummod TLR4,mRNA
R401 T534 T530 conj mRNA,control
R402 T535 T534 cc and,mRNA
R403 T536 T534 conj protein,mRNA
R404 T537 T538 advmod significantly,increased
R405 T538 T538 ROOT increased,increased
R406 T539 T538 xcomp starting,increased
R407 T540 T539 prep at,starting
R408 T541 T542 nummod 6,hours
R409 T542 T540 pobj hours,at
R410 T543 T546 mark after,peaked
R411 T544 T543 pobj ICH,after
R412 T545 T546 punct ",",peaked
R413 T546 T538 advcl peaked,increased
R414 T547 T546 prep on,peaked
R415 T548 T550 det the,day
R416 T549 T550 amod 3rd,day
R417 T550 T547 pobj day,on
R418 T551 T550 prep after,day
R419 T552 T551 pobj ICH,after
R420 T553 T546 punct ",",peaked
R421 T554 T546 cc and,peaked
R422 T555 T556 advmod then,decreased
R423 T556 T546 conj decreased,peaked
R424 T557 T556 cc but,decreased
R425 T558 T559 advmod still,maintained
R426 T559 T556 conj maintained,decreased
R427 T560 T559 prep at,maintained
R428 T561 T563 det a,level
R429 T562 T563 amod higher,level
R430 T563 T560 pobj level,at
R431 T564 T563 prep on,level
R432 T565 T567 det the,day
R433 T566 T567 amod 7th,day
R434 T567 T564 pobj day,on
R435 T568 T567 prep after,day
R436 T569 T574 nmod ICH,)
R437 T570 T571 punct (,P
R438 T571 T574 nmod P,)
R439 T572 T571 nummod <,P
R440 T573 T571 nummod .05,P
R441 T574 T563 punct ),level
R442 T575 T538 punct .,increased
R443 T576 T577 det The,level
R444 T577 T586 nsubj level,increased
R445 T578 T577 prep of,level
R446 T579 T578 pobj p-IκBα,of
R447 T580 T579 cc and,p-IκBα
R448 T581 T582 det the,activity
R449 T582 T579 conj activity,p-IκBα
R450 T583 T582 prep of,activity
R451 T584 T583 pobj NFκB,of
R452 T585 T586 advmod also,increased
R453 T586 T586 ROOT increased,increased
R454 T587 T586 prep in,increased
R455 T588 T589 det the,brain
R456 T589 T587 pobj brain,in
R457 T590 T592 mark after,compared
R458 T591 T592 nsubj ICH,compared
R459 T592 T586 prep compared,increased
R460 T593 T592 prep with,compared
R461 T594 T595 amod saline,control
R462 T595 T593 pobj control,with
R463 T596 T586 punct .,increased
R464 T597 T599 det The,study
R465 T598 T599 amod present,study
R466 T599 T601 nsubj study,suggests
R467 T600 T601 advmod firstly,suggests
R468 T601 T601 ROOT suggests,suggests
R469 T602 T606 mark that,participates
R470 T603 T604 compound TLR4-mediated,NFκB
R471 T604 T606 nsubj NFκB,participates
R472 T605 T604 acl signaling,NFκB
R473 T606 T601 ccomp participates,suggests
R474 T607 T606 prep in,participates
R475 T608 T609 det the,pathogenesis
R476 T609 T607 pobj pathogenesis,in
R477 T610 T609 prep of,pathogenesis
R478 T611 T610 pobj ICH,of
R479 T612 T611 punct ",",ICH
R480 T613 T615 nsubj which,become
R481 T614 T615 aux may,become
R482 T615 T611 relcl become,ICH
R483 T616 T618 det a,target
R484 T617 T618 amod therapeutic,target
R485 T618 T615 attr target,become
R486 T619 T618 prep for,target
R487 T620 T622 amod ICH-induced,damage
R488 T621 T622 compound brain,damage
R489 T622 T619 pobj damage,for
R490 T623 T601 punct .,suggests

bionlp-st-ge-2016-test-tees

Id Subject Object Predicate Lexical cue
T142 1174-1178 Protein denotes NFκB
T141 1160-1164 Protein denotes TLR4
T140 1057-1066 Positive_regulation denotes increased
T139 1047-1051 Protein denotes NFκB
T138 1020-1026 Protein denotes p-IκBα
T137 922-931 Negative_regulation denotes decreased
T136 839-848 Positive_regulation denotes increased
T135 803-812 Protein denotes TLR4 mRNA
T134 662-670 Positive_regulation denotes examined
T133 662-670 Positive_regulation denotes examined
T132 581-596 Phosphorylation denotes phosphorylation
T131 652-656 Protein denotes NFκB
T130 554-563 Protein denotes TLR4 mRNA
T129 441-451 Gene_expression denotes expression
T128 496-500 Protein denotes NFκB
T127 482-486 Protein denotes TLR4
T126 455-459 Protein denotes TLR4
T125 320-324 Protein denotes NFκB
T124 306-310 Protein denotes TLR4
T123 164-168 Protein denotes NFκB
T122 140-162 Protein denotes nuclear factor kappa-B
R21 T132 T134 themeOf phosphorylation,examined
R18 T126 T129 themeOf TLR4,expression
R19 T130 T132 themeOf TLR4 mRNA,phosphorylation
R20 T130 T133 themeOf TLR4 mRNA,examined
R22 T135 T136 themeOf TLR4 mRNA,increased
R23 T135 T137 themeOf TLR4 mRNA,decreased
R24 T138 T140 themeOf p-IκBα,increased

testone

Id Subject Object Predicate Lexical cue
T28 1057-1066 Positive_regulation denotes increased
T27 922-931 Negative_regulation denotes decreased
T26 839-848 Positive_regulation denotes increased
T25 441-451 Gene_expression denotes expression
T24 1160-1164 Protein denotes TLR4
T23 1022-1026 Protein denotes IκBα
T22 803-807 Protein denotes TLR4
T21 625-629 Protein denotes IκBα
T20 600-621 Protein denotes inhibitors of kappa B
T19 554-558 Protein denotes TLR4
T18 482-486 Protein denotes TLR4
T17 455-459 Protein denotes TLR4
T16 306-310 Protein denotes TLR4
T15 124-128 Protein denotes TLR4
T14 101-121 Protein denotes Toll-like receptor 4
R1 T15 T14 equivalentTo TLR4,Toll-like receptor 4
R2 T17 T25 themeOf TLR4,expression
R3 T21 T20 equivalentTo IκBα,inhibitors of kappa B

test3

Id Subject Object Predicate Lexical cue
T40 1160-1164 Protein denotes TLR4
T39 1022-1026 Protein denotes IκBα
T38 803-807 Protein denotes TLR4
T37 625-629 Protein denotes IκBα
T36 600-621 Protein denotes inhibitors of kappa B
T35 554-558 Protein denotes TLR4
T34 482-486 Protein denotes TLR4
T33 455-459 Protein denotes TLR4
T32 306-310 Protein denotes TLR4
T31 124-128 Protein denotes TLR4
T30 101-121 Protein denotes Toll-like receptor 4
T55 1160-1164 Protein denotes TLR4
T54 1022-1026 Protein denotes IκBα
T53 922-931 Negative_regulation denotes decreased
T52 839-848 Positive_regulation denotes increased
T51 803-807 Protein denotes TLR4
T50 625-629 Protein denotes IκBα
T49 600-621 Protein denotes inhibitors of kappa B
T48 554-558 Protein denotes TLR4
T47 482-486 Protein denotes TLR4
T46 455-459 Protein denotes TLR4
T45 441-451 Gene_expression denotes expression
T44 306-310 Protein denotes TLR4
T43 124-128 Protein denotes TLR4
T42 101-121 Protein denotes Toll-like receptor 4
R4 T43 T42 equivalentTo TLR4,Toll-like receptor 4
R5 T46 T45 themeOf TLR4,expression
R6 T50 T49 equivalentTo IκBα,inhibitors of kappa B
R7 T51 T52 themeOf TLR4,increased
R8 T51 T53 themeOf TLR4,decreased