PMC:2813722 / 22063-23646 JSONTXT

{"project":"MyTest","denotations":[{"id":"20161697-15351361-33634460","span":{"begin":396,"end":400},"obj":"15351361"},{"id":"20161697-16310813-33634461","span":{"begin":630,"end":634},"obj":"16310813"},{"id":"20161697-16513007-33634462","span":{"begin":650,"end":654},"obj":"16513007"},{"id":"20161697-18606038-33634463","span":{"begin":656,"end":660},"obj":"18606038"},{"id":"20161697-18061633-33634464","span":{"begin":675,"end":679},"obj":"18061633"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"We used a minimum norm method with the local autoregressive average (LAURA) to create a source model of the grand-averaged scalp data. Modeled source activation was then examined using GeoSource (EGI) for latencies between 250 and 500 ms post-stimulus. Given that relatively little is known about the sources underlying the N2 in young children, an underdetermined model was used (Michel et al., 2004; Luck, 2005). Regions of interest (ROIs) were defined functionally around the voxels of peak activation in the model, and also in light of source analyses of the N2 in studies conducted with North American children (Lamm et al., 2006; Lewis et al., 2006, 2008; Todd et al., 2008). Activation was then averaged across all voxels in each ROI for each participant in each go/no-go condition, and a single-source waveform was extracted for each ROI. This process yielded source activation waveforms for four hypothetical generators of scalp activation located generally in ventromedial prefrontal cortex, right ventrolateral prefrontal cortex, left ventrolateral prefrontal cortex, and dorsomedial prefrontal cortex. Figure 5 shows means and standard deviations of activation levels (in nA) extracted from these modeled sources for the two cultural groups for the peak N2 interval between 300 and 350 ms post-stimulus. To investigate cultural group differences in extracted activation levels for each of the four modeled sources, separate ANOVAs were carried out with cultural group as a between-subjects variable, and go/no-go condition and 50-ms interval as within-subjects variables."}

{"project":"2_test","denotations":[{"id":"20161697-15351361-33634460","span":{"begin":396,"end":400},"obj":"15351361"},{"id":"20161697-16310813-33634461","span":{"begin":630,"end":634},"obj":"16310813"},{"id":"20161697-16513007-33634462","span":{"begin":650,"end":654},"obj":"16513007"},{"id":"20161697-18606038-33634463","span":{"begin":656,"end":660},"obj":"18606038"},{"id":"20161697-18061633-33634464","span":{"begin":675,"end":679},"obj":"18061633"}],"text":"We used a minimum norm method with the local autoregressive average (LAURA) to create a source model of the grand-averaged scalp data. Modeled source activation was then examined using GeoSource (EGI) for latencies between 250 and 500 ms post-stimulus. Given that relatively little is known about the sources underlying the N2 in young children, an underdetermined model was used (Michel et al., 2004; Luck, 2005). Regions of interest (ROIs) were defined functionally around the voxels of peak activation in the model, and also in light of source analyses of the N2 in studies conducted with North American children (Lamm et al., 2006; Lewis et al., 2006, 2008; Todd et al., 2008). Activation was then averaged across all voxels in each ROI for each participant in each go/no-go condition, and a single-source waveform was extracted for each ROI. This process yielded source activation waveforms for four hypothetical generators of scalp activation located generally in ventromedial prefrontal cortex, right ventrolateral prefrontal cortex, left ventrolateral prefrontal cortex, and dorsomedial prefrontal cortex. Figure 5 shows means and standard deviations of activation levels (in nA) extracted from these modeled sources for the two cultural groups for the peak N2 interval between 300 and 350 ms post-stimulus. To investigate cultural group differences in extracted activation levels for each of the four modeled sources, separate ANOVAs were carried out with cultural group as a between-subjects variable, and go/no-go condition and 50-ms interval as within-subjects variables."}