PMC:2812710 / 11525-12639 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2812710","sourcedb":"PMC","sourceid":"2812710","source_url":"https://www.ncbi.nlm.nih.gov/pmc/2812710","text":"The different experimental hydrodynamics measurements can be expressed as intrinsic values, [η], [s], [D], [f], which are independent of the solvent properties (Cantor and Schimmel 1980; Tsvetkov 1989). Each of them is related to common macromolecular characteristics such as molar mass M and mean-square radius of gyration \u003c R 2 \u003e :2 3 4 5 with [η]: intrinsic viscosity; [s], [D], and [f]: intrinsic coefficients of velocity sedimentation, translational diffusion, and translational friction, correspondingly; N A is the Avogadro number, and Φ′ and P′ are the Flory hydrodynamic parameters. These relationships have a general meaning and are valid for any type of molecules/macromolecules. The values of the dimensionless parameters Φ′ and P′ depend, however, on the shape and asymmetry of the solute molecules and, in addition, on the hydrodynamic interactions between the different parts of the same molecule which exercise the friction in the liquid medium. The theoretical values of these parameters are obtained by solving the hydrodynamic problem and depend on the models and mathematical approximations.","divisions":[{"label":"label","span":{"begin":333,"end":334}},{"label":"label","span":{"begin":336,"end":337}},{"label":"label","span":{"begin":339,"end":340}},{"label":"label","span":{"begin":342,"end":343}}],"tracks":[]}