PMC:2806624 / 18928-22282 JSON TXT

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2_test

Id	Subject	Object	Predicate	Lexical cue
19917773-17785809-59851499	454-458	17785809	denotes	2007

pmc-enju-pas

Id	Subject	Object	Predicate	Lexical cue
T9089	217-219	IN	denotes	in
T9090	220-223	DT	denotes	the
T9091	224-233	NN	denotes	induction
T9092	234-236	IN	denotes	of
T9093	237-242	NN	denotes	Foxp3
T9094	242-243	-COMMA-	denotes	,
T9095	244-246	PRP	denotes	we
T9096	247-251	VB	denotes	used
T9097	252-256	NN	denotes	mice
T9098	257-259	IN	denotes	in
T9099	260-265	WDT	denotes	which
T9100	266-278	JJ	denotes	loxP-flanked
T9101	279-283	NN	denotes	Cbfb
T9102	284-291	NN	denotes	alleles
T9103	292-296	VB	denotes	were
T9104	297-308	VB	denotes	inactivated
T9105	309-311	IN	denotes	in
T9106	312-313	NN	denotes	T
T9107	314-319	NN	denotes	cells
T9108	320-327	IN	denotes	through
T9109	328-338	NN	denotes	expression
T9110	339-341	IN	denotes	of
T9111	342-343	DT	denotes	a
T9112	344-351	JJ	denotes	CD4-cre
T9113	352-361	NN	denotes	transgene
T9114	363-371	JJ	denotes	Retinoic
T9115	372-376	NN	denotes	acid
T9116	377-380	CC	denotes	and
T9117	381-386	NN	denotes	TGF-β
T9118	387-396	VB	denotes	synergize
T9119	397-399	IN	denotes	in
T9120	400-403	DT	denotes	the
T9121	404-413	NN	denotes	induction
T9122	414-416	IN	denotes	of
T9123	417-422	NN	denotes	Foxp3
T9124	423-425	IN	denotes	in
T9125	426-431	JJ	denotes	naive
T9126	432-433	NN	denotes	T
T9127	434-439	NN	denotes	cells
T9128	440-441	-LRB-	denotes	(
T9129	441-445	NNP	denotes	Kang
T9130	446-448	FW	denotes	et
T9131	449-452	FW	denotes	al.
T9132	452-453	-COMMA-	denotes	,
T9133	454-458	CD	denotes	2007
T9134	458-459	-RRB-	denotes	)
T9135	461-463	TO	denotes	To
T9136	464-475	VB	denotes	investigate
T9137	476-483	IN	denotes	whether
T9138	484-497	JJ	denotes	Runx-mediated
T9139	498-507	NN	denotes	induction
T9140	508-510	IN	denotes	of
T9141	511-516	NN	denotes	Foxp3
T9142	517-519	VB	denotes	is
T9143	520-529	JJ	denotes	dependent
T9144	530-532	IN	denotes	on
T9145	533-536	DT	denotes	the
T9146	537-547	NN	denotes	expression
T9147	548-550	IN	denotes	of
T9148	551-555	NN	denotes	CBFβ
T9149	555-556	-COMMA-	denotes	,
T9150	557-562	JJ	denotes	naive
T9151	563-567	JJ	denotes	CD4+
T9152	568-572	NN	denotes	CD8−
T9153	573-574	NN	denotes	T
T9154	575-580	NN	denotes	cells
T9155	581-585	IN	denotes	from
T9156	586-593	NN	denotes	CbfbF/F
T9157	594-601	JJ	denotes	CD4-cre
T9158	602-605	CC	denotes	and
T9159	606-613	NN	denotes	control
T9160	614-621	JJ	denotes	CbfbF/+
T9161	622-629	JJ	denotes	CD4-cre
T9162	630-634	NN	denotes	mice
T9163	635-639	VB	denotes	were
T9164	640-650	VB	denotes	stimulated
T9165	651-655	IN	denotes	with
T9166	656-667	JJ	denotes	anti-CD3/28
T9167	668-672	NN	denotes	mAbs
T9168	672-673	-COMMA-	denotes	,
T9169	674-682	JJ	denotes	retinoic
T9170	683-687	NN	denotes	acid
T9171	687-688	-COMMA-	denotes	,
T9172	689-692	CC	denotes	and
T9173	693-703	VB	denotes	increasing
T9174	704-718	NN	denotes	concentrations
T9175	719-721	IN	denotes	of
T9176	722-727	NN	denotes	TGF-β
T9177	729-734	IN	denotes	After
T9178	735-736	CD	denotes	3
T9179	737-738	NN	denotes	d
T9180	739-741	IN	denotes	in
T9181	742-749	NN	denotes	culture
T9182	749-750	-COMMA-	denotes	,
T9183	751-754	DT	denotes	the
T9184	755-760	NN	denotes	cells
T9185	761-765	VB	denotes	were
T9186	766-778	VB	denotes	restimulated
T9187	779-783	IN	denotes	with
T9188	784-787	NN	denotes	PMA
T9189	788-791	CC	denotes	and
T9190	792-801	NN	denotes	ionomycin
T9191	802-805	CC	denotes	and
T9192	806-814	VB	denotes	analyzed
T9193	815-818	IN	denotes	for
T9194	819-832	JJ	denotes	intracellular
T9195	833-838	NN	denotes	Foxp3
T9196	839-842	CC	denotes	and
T9197	843-848	NN	denotes	IFN-γ
T9198	849-859	NN	denotes	expression
T9199	861-866	NN	denotes	TGF-β
T9200	867-874	VB	denotes	induced
T9201	875-880	NN	denotes	Foxp3
T9202	881-883	IN	denotes	in
T9203	884-891	JJ	denotes	CbfbF/+
T9204	892-899	JJ	denotes	CD4-cre
T9205	900-905	NN	denotes	cells
T9206	906-908	IN	denotes	in
T9207	909-910	DT	denotes	a
T9208	911-915	NN	denotes	dose
T9209	916-925	JJ	denotes	dependent
T9210	926-932	NN	denotes	manner
T9211	932-933	-COMMA-	denotes	,
T9212	934-937	CC	denotes	and
T9213	938-942	DT	denotes	this
T9214	943-946	VB	denotes	was
T9215	947-960	RB	denotes	significantly
T9216	961-968	VB	denotes	reduced
T9217	969-971	IN	denotes	in
T9218	972-979	NN	denotes	CbfbF/F
T9219	980-987	JJ	denotes	CD4-cre
T9220	988-993	NN	denotes	cells
T9221	995-1003	JJ	denotes	Retinoic
T9222	1004-1008	NN	denotes	acid
T9223	1009-1017	VB	denotes	enhanced
T9224	1018-1023	NN	denotes	Foxp3
T9225	1024-1034	NN	denotes	expression
T9226	1035-1039	RB	denotes	even
T9227	1040-1042	IN	denotes	in
T9228	1043-1045	CD	denotes	20
T9229	1046-1051	NN	denotes	pg/ml
T9230	1052-1054	IN	denotes	of
T9231	1055-1060	NN	denotes	TGF-β
T9232	1061-1064	CC	denotes	and
T9233	1065-1069	JJ	denotes	more
T9234	1070-1074	IN	denotes	than
T9235	1075-1077	CD	denotes	95
T9236	1077-1078	NN	denotes	%
T9237	1079-1081	IN	denotes	of
T9238	1082-1085	DT	denotes	the
T9239	1086-1090	JJ	denotes	CD4+
T9240	1091-1092	NN	denotes	T
T9241	1093-1098	NN	denotes	cells
T9242	1099-1103	IN	denotes	from
T9243	1104-1111	JJ	denotes	CbfbF/+
T9244	1112-1119	JJ	denotes	CD4-cre
T9245	1120-1124	NN	denotes	mice
T9246	1125-1131	VB	denotes	became
T9247	1132-1138	JJ	denotes	Foxp3+
T9248	1139-1141	IN	denotes	in
T9249	1142-1145	CD	denotes	100
T9250	1146-1149	CC	denotes	and
T9251	1150-1153	CD	denotes	500
T9252	1154-1159	NN	denotes	pg/ml
T9253	1160-1165	NN	denotes	TGF-β
T9254	1166-1171	NN	denotes	doses
T9255	1173-1176	DT	denotes	The
T9256	1177-1186	NN	denotes	induction
T9257	1187-1189	IN	denotes	of
T9258	1190-1195	NN	denotes	Foxp3
T9259	1196-1199	VB	denotes	was
T9260	1200-1205	RB	denotes	again
T9261	1206-1219	RB	denotes	significantly
T9262	1220-1225	JJ	denotes	lower
T9263	1226-1228	IN	denotes	in
T9264	1229-1236	NN	denotes	CbfbF/F
T9265	1237-1244	JJ	denotes	CD4-cre
T9266	1245-1249	JJ	denotes	CD4+
T9267	1250-1251	NN	denotes	T
T9268	1252-1257	NN	denotes	cells
T9269	1258-1262	RB	denotes	even
T9270	1263-1265	IN	denotes	in
T9271	1266-1269	DT	denotes	the
T9272	1270-1278	NN	denotes	presence
T9273	1279-1281	IN	denotes	of
T9274	1282-1290	JJ	denotes	retinoic
T9275	1291-1295	NN	denotes	acid
T9276	1295-1296	-COMMA-	denotes	,
T9277	1297-1310	VB	denotes	demonstrating
T9278	1311-1315	IN	denotes	that
T9279	1316-1326	NN	denotes	deficiency
T9280	1327-1329	IN	denotes	in
T9281	1330-1334	NN	denotes	Runx
T9282	1335-1342	NN	denotes	binding
T9283	1343-1345	TO	denotes	to
T9284	1346-1349	NN	denotes	DNA
T9285	1350-1357	VB	denotes	affects
T9286	1358-1361	DT	denotes	the
T9287	1362-1367	NN	denotes	TGF-β
T9288	1368-1377	NN	denotes	induction
T9289	1378-1380	IN	denotes	of
T9290	1381-1386	NN	denotes	Foxp3
T9291	1387-1389	IN	denotes	in
T9292	1390-1391	NN	denotes	T
T9293	1392-1395	NN	denotes	reg
T9294	1396-1401	NN	denotes	cells
T9295	1402-1403	-LRB-	denotes	(
T9296	1403-1407	NN	denotes	Fig.
T9297	1408-1409	CD	denotes	5
T9298	1410-1411	NN	denotes	A
T9299	1411-1412	-RRB-	denotes	)
T9300	1414-1419	EX	denotes	There
T9301	1420-1423	VB	denotes	was
T9302	1424-1426	DT	denotes	no
T9303	1427-1437	NN	denotes	difference
T9304	1438-1440	IN	denotes	in
T9305	1441-1444	DT	denotes	the
T9306	1445-1454	NN	denotes	induction
T9307	1455-1457	IN	denotes	of
T9308	1458-1463	NN	denotes	Foxp3
T9309	1464-1468	WRB	denotes	when
T9310	1469-1479	JJ	denotes	endogenous
T9311	1480-1484	NN	denotes	IL-4
T9312	1485-1488	CC	denotes	and
T9313	1489-1494	NN	denotes	IFN-γ
T9314	1495-1499	VB	denotes	were
T9315	1500-1511	VB	denotes	neutralized
T9316	1512-1513	-LRB-	denotes	(
T9317	1513-1517	NNP	denotes	Fig.
T9318	1518-1520	NN	denotes	S6
T9319	1520-1521	-RRB-	denotes	)
T9320	2607-2610	DT	denotes	The
T9321	2611-2621	NN	denotes	importance
T9322	2622-2624	IN	denotes	of
T9323	2625-2629	NN	denotes	RUNX
T9324	2630-2643	NN	denotes	transcription
T9325	2644-2651	NN	denotes	factors
T9326	2652-2655	IN	denotes	for
T9327	2656-2659	DT	denotes	the
T9328	2660-2662	FW	denotes	in
T9329	2663-2667	FW	denotes	vivo
T9330	2668-2678	NN	denotes	conversion
T9331	2679-2681	IN	denotes	of
T9332	2682-2687	JJ	denotes	naive
T9333	2688-2692	JJ	denotes	CD4+
T9334	2693-2694	NN	denotes	T
T9335	2695-2700	NN	denotes	cells
T9336	2701-2705	IN	denotes	into
T9337	2706-2708	NN	denotes	iT
T9338	2709-2712	NN	denotes	reg
T9339	2713-2718	NN	denotes	cells
T9340	2719-2722	VB	denotes	was
T9341	2723-2731	VB	denotes	examined
T9342	2733-2740	NN	denotes	Control
T9343	2741-2748	NN	denotes	CbfbF/F
T9344	2749-2751	CC	denotes	or
T9345	2752-2759	NN	denotes	CbfbF/F
T9346	2760-2767	JJ	denotes	CD4-cre
T9347	2768-2773	JJ	denotes	naive
T9348	2774-2775	NN	denotes	T
T9349	2776-2781	NN	denotes	cells
T9350	2781-2782	-COMMA-	denotes	,
T9351	2783-2792	VB	denotes	harboring
T9352	2793-2794	DT	denotes	a
T9353	2795-2809	NN	denotes	Foxp3-IRES-GFP
T9354	2810-2816	NN	denotes	allele
T9355	2817-2821	VB	denotes	were
T9356	2822-2832	RB	denotes	adoptively
T9357	2833-2844	VB	denotes	transferred
T9358	2845-2849	IN	denotes	into
T9359	2850-2857	NN	denotes	Rag2−/−
T9360	2858-2862	NN	denotes	mice
T9361	2864-2865	CD	denotes	6
T9362	2866-2868	NN	denotes	wk
T9363	2869-2874	RB	denotes	later
T9364	2874-2875	-COMMA-	denotes	,
T9365	2876-2880	JJ	denotes	CD4+
T9366	2881-2882	NN	denotes	T
T9367	2883-2888	NN	denotes	cells
T9368	2889-2891	IN	denotes	in
T9369	2892-2898	NN	denotes	spleen
T9370	2898-2899	-COMMA-	denotes	,
T9371	2900-2910	JJ	denotes	mesenteric
T9372	2911-2916	NN	denotes	lymph
T9373	2917-2921	NN	denotes	node
T9374	2921-2922	-COMMA-	denotes	,
T9375	2923-2926	CC	denotes	and
T9376	2927-2933	NN	denotes	lamina
T9377	2934-2941	NN	denotes	propria
T9378	2942-2944	IN	denotes	of
T9379	2945-2948	DT	denotes	the
T9380	2949-2954	JJ	denotes	small
T9381	2955-2964	NN	denotes	intestine
T9382	2965-2969	VB	denotes	were
T9383	2970-2978	VB	denotes	analyzed
T9384	2979-2982	IN	denotes	for
T9385	2983-2992	NN	denotes	Foxp3-GFP
T9386	2993-3003	NN	denotes	expression
T9387	3004-3005	-LRB-	denotes	(
T9388	3005-3009	NN	denotes	Fig.
T9389	3010-3011	CD	denotes	5
T9390	3012-3013	NN	denotes	B
T9391	3013-3014	-RRB-	denotes	)
T9392	3016-3021	EX	denotes	There
T9393	3022-3025	VB	denotes	was
T9394	3026-3027	DT	denotes	a
T9395	3028-3040	RB	denotes	consistently
T9396	3041-3046	JJ	denotes	lower
T9397	3047-3057	NN	denotes	percentage
T9398	3058-3060	IN	denotes	of
T9399	3061-3065	JJ	denotes	CD4+
T9400	3066-3067	NN	denotes	T
T9401	3068-3073	NN	denotes	cells
T9402	3074-3078	WDT	denotes	that
T9403	3079-3082	VB	denotes	had
T9404	3083-3092	VB	denotes	developed
T9405	3093-3098	NN	denotes	Foxp3
T9406	3099-3109	NN	denotes	expression
T9407	3110-3112	IN	denotes	in
T9408	3113-3116	DT	denotes	the
T9409	3117-3127	JJ	denotes	mesenteric
T9410	3128-3133	NN	denotes	lymph
T9411	3134-3138	NN	denotes	node
T9412	3139-3142	CC	denotes	and
T9413	3143-3149	NN	denotes	lamina
T9414	3150-3157	NN	denotes	propria
T9415	3158-3160	IN	denotes	of
T9416	3161-3165	NN	denotes	mice
T9417	3166-3177	VB	denotes	transferred
T9418	3178-3182	IN	denotes	with
T9419	3183-3190	NN	denotes	CbfbF/F
T9420	3191-3198	JJ	denotes	CD4-cre
T9421	3199-3204	NN	denotes	cells
T9422	3205-3213	VB	denotes	compared
T9423	3214-3218	IN	denotes	with
T9424	3219-3226	JJ	denotes	control
T9425	3227-3232	NN	denotes	cells
T9426	3233-3234	-LRB-	denotes	(
T9427	3234-3238	NN	denotes	Fig.
T9428	3239-3240	CD	denotes	5
T9429	3240-3241	-COMMA-	denotes	,
T9430	3242-3243	NN	denotes	B
T9431	3244-3247	CC	denotes	and
T9432	3248-3249	NN	denotes	C
T9433	3249-3250	-RRB-	denotes	)
T9434	3252-3257	DT	denotes	These
T9435	3258-3262	NN	denotes	data
T9436	3263-3269	VB	denotes	affirm
T9437	3270-3273	DT	denotes	the
T9438	3274-3286	NN	denotes	significance
T9439	3287-3289	IN	denotes	of
T9440	3290-3294	NN	denotes	RUNX
T9441	3295-3303	NN	denotes	proteins
T9442	3304-3307	IN	denotes	for
T9443	3308-3311	DT	denotes	the
T9444	3312-3314	FW	denotes	in
T9445	3315-3319	FW	denotes	vivo
T9446	3320-3330	NN	denotes	generation
T9447	3331-3333	IN	denotes	of
T9448	3334-3338	JJ	denotes	CD4+
T9449	3339-3345	JJ	denotes	Foxp3+
T9450	3346-3347	NN	denotes	T
T9451	3348-3353	NN	denotes	cells
T31441	1534-1544	VB	denotes	Diminished
T31442	1545-1553	NN	denotes	capacity
T31443	1554-1556	IN	denotes	of
T31444	1557-1571	JJ	denotes	Cbfb-deficient
T31445	1572-1579	JJ	denotes	CD4-cre
T31446	1580-1584	NN	denotes	mice
T31447	1585-1586	NN	denotes	T
T31448	1587-1592	NN	denotes	cells
T31449	1593-1595	IN	denotes	in
T31450	1596-1599	DT	denotes	the
T31451	1600-1610	NN	denotes	generation
T31452	1611-1613	IN	denotes	of
T31453	1614-1620	JJ	denotes	Foxp3+
T31454	1621-1625	JJ	denotes	CD4+
T31455	1626-1627	NN	denotes	T
T31456	1628-1634	NN	denotes	cells.
T31457	1635-1636	-LRB-	denotes	(
T31458	1636-1637	NN	denotes	A
T31459	1637-1638	-RRB-	denotes	)
T31460	1639-1652	JJ	denotes	FACS-purified
T31461	1653-1658	JJ	denotes	naive
T31462	1659-1663	JJ	denotes	CD4+
T31463	1664-1668	NN	denotes	CD8−
T31464	1669-1670	NN	denotes	T
T31465	1671-1676	NN	denotes	cells
T31466	1677-1681	IN	denotes	from
T31467	1682-1689	NN	denotes	CbfbF/F
T31468	1690-1697	JJ	denotes	CD4-cre
T31469	1698-1701	CC	denotes	and
T31470	1702-1709	NN	denotes	control
T31471	1710-1717	JJ	denotes	CbfbF/+
T31472	1718-1725	JJ	denotes	CD4-cre
T31473	1726-1730	NN	denotes	mice
T31474	1731-1735	VB	denotes	were
T31475	1736-1745	VB	denotes	activated
T31476	1746-1748	FW	denotes	in
T31477	1749-1754	FW	denotes	vitro
T31478	1755-1759	IN	denotes	with
T31479	1760-1771	JJ	denotes	anti-CD3/28
T31480	1772-1775	NN	denotes	mAb
T31481	1775-1776	-COMMA-	denotes	,
T31482	1777-1779	CD	denotes	50
T31483	1780-1784	NN	denotes	U/ml
T31484	1785-1789	NN	denotes	IL-2
T31485	1789-1790	-COMMA-	denotes	,
T31486	1791-1792	IN	denotes	±
T31487	1793-1795	CD	denotes	10
T31488	1796-1798	NN	denotes	nM
T31489	1799-1807	JJ	denotes	retinoic
T31490	1808-1812	NN	denotes	acid
T31491	1813-1814	-LRB-	denotes	(
T31492	1814-1816	NN	denotes	RA
T31493	1816-1817	-RRB-	denotes	)
T31494	1817-1818	-COMMA-	denotes	,
T31495	1819-1822	CC	denotes	and
T31496	1823-1833	VB	denotes	increasing
T31497	1834-1848	NN	denotes	concentrations
T31498	1849-1851	IN	denotes	of
T31499	1852-1857	NN	denotes	TGF-β
T31500	1859-1864	IN	denotes	After
T31501	1865-1866	CD	denotes	3
T31502	1867-1868	NN	denotes	d
T31503	1869-1871	IN	denotes	in
T31504	1872-1879	NN	denotes	culture
T31505	1879-1880	-COMMA-	denotes	,
T31506	1881-1884	DT	denotes	the
T31507	1885-1890	NN	denotes	cells
T31508	1891-1895	VB	denotes	were
T31509	1896-1908	VB	denotes	restimulated
T31510	1909-1913	IN	denotes	with
T31511	1914-1917	NN	denotes	PMA
T31512	1918-1919	SYM	denotes	+
T31513	1920-1929	NN	denotes	ionomycin
T31514	1929-1930	-COMMA-	denotes	,
T31515	1931-1934	CC	denotes	and
T31516	1935-1939	RB	denotes	then
T31517	1940-1948	VB	denotes	analyzed
T31518	1949-1952	IN	denotes	for
T31519	1953-1966	JJ	denotes	intracellular
T31520	1967-1972	NN	denotes	Foxp3
T31521	1973-1976	CC	denotes	and
T31522	1977-1982	NN	denotes	IFN-γ
T31523	1983-1993	NN	denotes	expression
T31524	1995-1998	CD	denotes	One
T31525	1999-2001	IN	denotes	of
T31526	2002-2006	CD	denotes	five
T31527	2007-2018	NN	denotes	experiments
T31528	2019-2021	VB	denotes	is
T31529	2022-2028	NN	denotes	shown.
T31530	2029-2030	-LRB-	denotes	(
T31531	2030-2031	NN	denotes	B
T31532	2031-2032	-RRB-	denotes	)
T31533	2033-2038	JJ	denotes	Naive
T31534	2039-2043	JJ	denotes	CD4+
T31535	2044-2045	NN	denotes	T
T31536	2046-2051	NN	denotes	cells
T31537	2052-2056	IN	denotes	from
T31538	2057-2061	NN	denotes	Cbfb
T31539	2062-2069	JJ	denotes	CD4-cre
T31540	2070-2072	CC	denotes	or
T31541	2073-2080	NN	denotes	control
T31542	2081-2085	NN	denotes	mice
T31543	2086-2087	-LRB-	denotes	(
T31544	2087-2096	VB	denotes	harboring
T31545	2097-2098	DT	denotes	a
T31546	2099-2113	NN	denotes	Foxp3-IRES-GFP
T31547	2114-2120	NN	denotes	allele
T31548	2120-2121	-RRB-	denotes	)
T31549	2122-2126	VB	denotes	were
T31550	2127-2137	RB	denotes	adoptively
T31551	2138-2149	VB	denotes	transferred
T31552	2150-2154	IN	denotes	into
T31553	2155-2168	JJ	denotes	Rag-deficient
T31554	2169-2173	NN	denotes	mice
T31555	2174-2175	-LRB-	denotes	(
T31556	2175-2176	CD	denotes	5
T31557	2177-2178	NN	denotes	×
T31558	2179-2182	CD	denotes	106
T31559	2183-2188	NN	denotes	cells
T31560	2189-2192	IN	denotes	per
T31561	2193-2201	NN	denotes	transfer
T31562	2201-2202	-RRB-	denotes	)
T31563	2204-2205	CD	denotes	6
T31564	2206-2208	NN	denotes	wk
T31565	2209-2214	RB	denotes	later
T31566	2214-2215	-COMMA-	denotes	,
T31567	2216-2225	JJ	denotes	TCRβ+CD4+
T31568	2226-2231	NN	denotes	cells
T31569	2232-2236	IN	denotes	from
T31570	2237-2240	DT	denotes	the
T31571	2241-2247	NN	denotes	spleen
T31572	2247-2248	-COMMA-	denotes	,
T31573	2249-2259	JJ	denotes	mesenteric
T31574	2260-2265	NN	denotes	lymph
T31575	2266-2270	NN	denotes	node
T31576	2271-2272	-LRB-	denotes	(
T31577	2272-2275	NN	denotes	MLN
T31578	2275-2276	-RRB-	denotes	)
T31579	2276-2277	-COMMA-	denotes	,
T31580	2278-2281	CC	denotes	and
T31581	2282-2288	NN	denotes	lamina
T31582	2289-2296	NN	denotes	propria
T31583	2297-2299	IN	denotes	of
T31584	2300-2303	DT	denotes	the
T31585	2304-2309	JJ	denotes	small
T31586	2310-2319	NN	denotes	intestine
T31587	2320-2321	-LRB-	denotes	(
T31588	2321-2323	NN	denotes	LP
T31589	2323-2324	-RRB-	denotes	)
T31590	2325-2329	VB	denotes	were
T31591	2330-2338	VB	denotes	analyzed
T31592	2339-2342	IN	denotes	for
T31593	2343-2352	NN	denotes	Foxp3-GFP
T31594	2353-2363	NN	denotes	expression
T31595	2365-2372	NN	denotes	Results
T31596	2373-2377	IN	denotes	from
T31597	2378-2381	CD	denotes	one
T31598	2382-2384	IN	denotes	of
T31599	2385-2389	CD	denotes	four
T31600	2390-2397	NN	denotes	CbfbF/F
T31601	2398-2405	JJ	denotes	CD4-cre
T31602	2406-2409	CC	denotes	and
T31603	2410-2417	NN	denotes	control
T31604	2418-2425	JJ	denotes	CbfbF/+
T31605	2426-2433	JJ	denotes	CD4-cre
T31606	2434-2438	NN	denotes	mice
T31607	2439-2443	IN	denotes	with
T31608	2444-2448	JJ	denotes	same
T31609	2449-2457	NN	denotes	findings
T31610	2458-2461	VB	denotes	are
T31611	2462-2467	VB	denotes	shown
T31612	2469-2472	DT	denotes	The
T31613	2473-2477	NN	denotes	data
T31614	2478-2482	IN	denotes	from
T31615	2483-2487	CD	denotes	four
T31616	2488-2492	NN	denotes	sets
T31617	2493-2495	IN	denotes	of
T31618	2496-2500	NN	denotes	mice
T31619	2501-2503	VB	denotes	is
T31620	2504-2509	VB	denotes	shown
T31621	2510-2512	IN	denotes	in
T31622	2513-2515	NNP	denotes	C.
T31623	2516-2527	NNP	denotes	Statistical
T31624	2528-2536	NN	denotes	analysis
T31625	2537-2540	VB	denotes	was
T31626	2541-2550	VB	denotes	performed
T31627	2551-2555	IN	denotes	with
T31628	2556-2568	JJ	denotes	Mann-Whitney
T31629	2569-2570	NN	denotes	U
T31630	2571-2576	NN	denotes	test.
T31631	2577-2578	SYM	denotes	*
T31632	2578-2579	-COMMA-	denotes	,
T31633	2580-2581	NN	denotes	P
T31634	2582-2583	SYM	denotes	<
T31635	2584-2588	CD	denotes	0.05
T31636	2589-2596	IN	denotes	between
T31637	2597-2603	NN	denotes	groups
T9049	0-4	NN	denotes	Role
T9050	5-7	IN	denotes	of
T9051	8-12	NN	denotes	CBFβ
T9052	13-15	IN	denotes	in
T9053	16-19	DT	denotes	the
T9054	20-29	NN	denotes	induction
T9055	30-32	IN	denotes	of
T9056	33-38	NN	denotes	Foxp3
T9057	39-43	NN	denotes	CBFβ
T9058	43-44	-COMMA-	denotes	,
T9059	45-46	DT	denotes	a
T9060	47-53	JJ	denotes	common
T9061	54-62	NN	denotes	cofactor
T9062	63-65	IN	denotes	of
T9063	66-69	DT	denotes	all
T9064	70-74	NN	denotes	RUNX
T9065	75-83	NN	denotes	proteins
T9066	83-84	-COMMA-	denotes	,
T9067	85-95	VB	denotes	stabilizes
T9068	96-99	CC	denotes	and
T9069	100-109	VB	denotes	increases
T9070	110-113	DT	denotes	the
T9071	114-121	NN	denotes	binding
T9072	122-124	IN	denotes	of
T9073	125-128	DT	denotes	the
T9074	129-133	NN	denotes	runt
T9075	134-140	NN	denotes	domain
T9076	141-143	TO	denotes	to
T9077	144-150	VB	denotes	target
T9078	151-154	NN	denotes	DNA
T9079	155-164	NN	denotes	sequences
T9080	166-168	TO	denotes	To
T9081	169-175	VB	denotes	target
T9082	176-179	DT	denotes	all
T9083	180-184	NN	denotes	Runx
T9084	185-193	NN	denotes	proteins
T9085	194-198	WDT	denotes	that
T9086	199-204	MD	denotes	might
T9087	205-207	VB	denotes	be
T9088	208-216	VB	denotes	involved
R7178	T9084	T9088	arg2Of	proteins,involved
R7179	T9088	T9086	arg2Of	involved,might
R7180	T9088	T9087	arg2Of	involved,be
R7181	T9088	T9089	arg1Of	involved,in
R7182	T9091	T9089	arg2Of	induction,in
R7183	T9091	T9090	arg1Of	induction,the
R7184	T9091	T9092	arg1Of	induction,of
R7185	T9093	T9092	arg2Of	Foxp3,of
R7186	T9095	T9081	arg1Of	we,target
R7187	T9095	T9096	arg1Of	we,used
R7188	T9096	T9080	modOf	used,To
R7189	T9096	T9094	arg1Of	used,","
R7190	T9097	T9096	arg2Of	mice,used
R7191	T9097	T9098	arg2Of	mice,in
R7192	T9097	T9099	arg1Of	mice,which
R7193	T9102	T9100	arg1Of	alleles,loxP-flanked
R7194	T9102	T9101	arg1Of	alleles,Cbfb
R7195	T9102	T9103	arg1Of	alleles,were
R7196	T9102	T9104	arg2Of	alleles,inactivated
R7197	T9104	T9098	arg1Of	inactivated,in
R7198	T9104	T9103	arg2Of	inactivated,were
R7199	T9104	T9105	arg1Of	inactivated,in
R7200	T9104	T9108	arg1Of	inactivated,through
R7201	T9107	T9105	arg2Of	cells,in
R7202	T9107	T9106	arg1Of	cells,T
R7203	T9109	T9108	arg2Of	expression,through
R7204	T9109	T9110	arg1Of	expression,of
R7205	T9113	T9110	arg2Of	transgene,of
R7206	T9113	T9111	arg1Of	transgene,a
R7207	T9113	T9112	arg1Of	transgene,CD4-cre
R7208	T9115	T9114	arg1Of	acid,Retinoic
R7209	T9115	T9116	arg1Of	acid,and
R7210	T9116	T9118	arg1Of	and,synergize
R7211	T9117	T9116	arg2Of	TGF-β,and
R7212	T9118	T9119	arg1Of	synergize,in
R7213	T9118	T9128	arg1Of	synergize,(
R7214	T9121	T9119	arg2Of	induction,in
R7215	T9121	T9120	arg1Of	induction,the
R7216	T9121	T9122	arg1Of	induction,of
R7217	T9121	T9124	arg1Of	induction,in
R7218	T9123	T9122	arg2Of	Foxp3,of
R7219	T9127	T9124	arg2Of	cells,in
R7220	T9127	T9125	arg1Of	cells,naive
R7221	T9127	T9126	arg1Of	cells,T
R7222	T9129	T9128	arg2Of	Kang,(
R7223	T9129	T9130	arg1Of	Kang,et
R7224	T9129	T9131	arg1Of	Kang,al.
R7225	T9129	T9132	arg1Of	Kang,","
R7226	T9133	T9132	arg2Of	2007,","
R7227	T9134	T9128	arg3Of	),(
R7228	T9136	T9135	arg1Of	investigate,To
R7229	T9139	T9138	arg1Of	induction,Runx-mediated
R7230	T9139	T9140	arg1Of	induction,of
R7231	T9139	T9142	arg1Of	induction,is
R7232	T9139	T9143	arg1Of	induction,dependent
R7233	T9141	T9140	arg2Of	Foxp3,of
R7234	T9142	T9136	arg2Of	is,investigate
R7235	T9142	T9137	arg1Of	is,whether
R7236	T9143	T9142	arg2Of	dependent,is
R7237	T9143	T9144	arg1Of	dependent,on
R7238	T9146	T9144	arg2Of	expression,on
R7239	T9146	T9145	arg1Of	expression,the
R7240	T9146	T9147	arg1Of	expression,of
R7241	T9148	T9147	arg2Of	CBFβ,of
R7242	T9154	T9136	arg1Of	cells,investigate
R7243	T9154	T9150	arg1Of	cells,naive
R7244	T9154	T9151	arg1Of	cells,CD4+
R7245	T9154	T9152	arg1Of	cells,CD8−
R7246	T9154	T9153	arg1Of	cells,T
R7247	T9154	T9155	arg1Of	cells,from
R7248	T9154	T9163	arg1Of	cells,were
R7249	T9154	T9164	arg2Of	cells,stimulated
R7250	T9157	T9158	arg1Of	CD4-cre,and
R7251	T9158	T9156	arg1Of	and,CbfbF/F
R7252	T9159	T9158	arg2Of	control,and
R7253	T9162	T9155	arg2Of	mice,from
R7254	T9162	T9157	arg1Of	mice,CD4-cre
R7255	T9162	T9159	arg1Of	mice,control
R7256	T9162	T9160	arg1Of	mice,CbfbF/+
R7257	T9162	T9161	arg1Of	mice,CD4-cre
R7258	T9164	T9135	modOf	stimulated,To
R7259	T9164	T9149	arg1Of	stimulated,","
R7260	T9164	T9163	arg2Of	stimulated,were
R7261	T9164	T9165	arg1Of	stimulated,with
R7262	T9167	T9166	arg1Of	mAbs,anti-CD3/28
R7263	T9167	T9168	arg1Of	mAbs,","
R7264	T9168	T9172	arg1Of	",",and
R7265	T9170	T9168	arg2Of	acid,","
R7266	T9170	T9169	arg1Of	acid,retinoic
R7267	T9172	T9165	arg2Of	and,with
R7268	T9172	T9171	arg1Of	and,","
R7269	T9174	T9172	arg2Of	concentrations,and
R7270	T9174	T9173	arg1Of	concentrations,increasing
R7271	T9174	T9175	arg1Of	concentrations,of
R7272	T9176	T9175	arg2Of	TGF-β,of
R7273	T9179	T9177	arg2Of	d,After
R7274	T9179	T9178	arg1Of	d,3
R7275	T9179	T9180	arg1Of	d,in
R7276	T9181	T9180	arg2Of	culture,in
R7277	T9184	T9183	arg1Of	cells,the
R7278	T9184	T9185	arg1Of	cells,were
R7279	T9184	T9186	arg2Of	cells,restimulated
R7280	T9184	T9192	arg2Of	cells,analyzed
R7281	T9186	T9187	arg1Of	restimulated,with
R7282	T9186	T9191	arg1Of	restimulated,and
R7283	T9188	T9189	arg1Of	PMA,and
R7284	T9189	T9187	arg2Of	and,with
R7285	T9190	T9189	arg2Of	ionomycin,and
R7286	T9191	T9177	arg1Of	and,After
R7287	T9191	T9182	arg1Of	and,","
R7288	T9191	T9185	arg2Of	and,were
R7289	T9192	T9191	arg2Of	analyzed,and
R7290	T9192	T9193	arg1Of	analyzed,for
R7291	T9195	T9196	arg1Of	Foxp3,and
R7292	T9197	T9196	arg2Of	IFN-γ,and
R7293	T9198	T9193	arg2Of	expression,for
R7294	T9198	T9194	arg1Of	expression,intracellular
R7295	T9198	T9195	arg1Of	expression,Foxp3
R7296	T9198	T9197	arg1Of	expression,IFN-γ
R7297	T9199	T9200	arg1Of	TGF-β,induced
R7298	T9200	T9202	arg1Of	induced,in
R7299	T9200	T9206	arg1Of	induced,in
R7300	T9200	T9212	arg1Of	induced,and
R7301	T9201	T9200	arg2Of	Foxp3,induced
R7302	T9205	T9202	arg2Of	cells,in
R7303	T9205	T9203	arg1Of	cells,CbfbF/+
R7304	T9205	T9204	arg1Of	cells,CD4-cre
R7305	T9209	T9208	arg1Of	dependent,dose
R7306	T9210	T9206	arg2Of	manner,in
R7307	T9210	T9207	arg1Of	manner,a
R7308	T9210	T9209	arg1Of	manner,dependent
R7309	T9212	T9211	arg1Of	and,","
R7310	T9213	T9214	arg1Of	this,was
R7311	T9213	T9216	arg2Of	this,reduced
R7312	T9216	T9212	arg2Of	reduced,and
R7313	T9216	T9214	arg2Of	reduced,was
R7314	T9216	T9215	arg1Of	reduced,significantly
R7315	T9216	T9217	arg1Of	reduced,in
R7316	T9220	T9217	arg2Of	cells,in
R7317	T9220	T9218	arg1Of	cells,CbfbF/F
R7318	T9220	T9219	arg1Of	cells,CD4-cre
R7319	T9225	T9221	arg1Of	expression,Retinoic
R7320	T9225	T9222	arg1Of	expression,acid
R7321	T9225	T9223	arg2Of	expression,enhanced
R7322	T9225	T9224	arg1Of	expression,Foxp3
R7323	T9225	T9246	arg1Of	expression,became
R7324	T9225	T9247	arg1Of	expression,Foxp3+
R7325	T9227	T9226	arg1Of	in,even
R7326	T9229	T9227	arg2Of	pg/ml,in
R7327	T9229	T9228	arg1Of	pg/ml,20
R7328	T9229	T9230	arg1Of	pg/ml,of
R7329	T9231	T9232	arg1Of	TGF-β,and
R7330	T9232	T9230	arg2Of	and,of
R7331	T9232	T9242	arg1Of	and,from
R7332	T9233	T9234	arg1Of	more,than
R7333	T9235	T9234	arg2Of	95,than
R7334	T9236	T9232	arg2Of	%,and
R7335	T9236	T9233	arg1Of	%,more
R7336	T9236	T9237	arg1Of	%,of
R7337	T9241	T9237	arg2Of	cells,of
R7338	T9241	T9238	arg1Of	cells,the
R7339	T9241	T9239	arg1Of	cells,CD4+
R7340	T9241	T9240	arg1Of	cells,T
R7341	T9245	T9242	arg2Of	mice,from
R7342	T9245	T9243	arg1Of	mice,CbfbF/+
R7343	T9245	T9244	arg1Of	mice,CD4-cre
R7344	T9246	T9227	arg1Of	became,in
R7345	T9246	T9248	arg1Of	became,in
R7346	T9247	T9246	arg2Of	Foxp3+,became
R7347	T9249	T9250	arg1Of	100,and
R7348	T9251	T9250	arg2Of	500,and
R7349	T9254	T9248	arg2Of	doses,in
R7350	T9254	T9249	arg1Of	doses,100
R7351	T9254	T9251	arg1Of	doses,500
R7352	T9254	T9252	arg1Of	doses,pg/ml
R7353	T9254	T9253	arg1Of	doses,TGF-β
R7354	T9256	T9255	arg1Of	induction,The
R7355	T9256	T9257	arg1Of	induction,of
R7356	T9256	T9259	arg1Of	induction,was
R7357	T9256	T9262	arg1Of	induction,lower
R7358	T9258	T9257	arg2Of	Foxp3,of
R7359	T9259	T9260	arg1Of	was,again
R7360	T9259	T9270	arg1Of	was,in
R7361	T9259	T9276	arg1Of	was,","
R7362	T9259	T9277	modOf	was,demonstrating
R7363	T9262	T9259	arg2Of	lower,was
R7364	T9262	T9261	arg1Of	lower,significantly
R7365	T9262	T9263	arg1Of	lower,in
R7366	T9268	T9263	arg2Of	cells,in
R7367	T9268	T9264	arg1Of	cells,CbfbF/F
R7368	T9268	T9265	arg1Of	cells,CD4-cre
R7369	T9268	T9266	arg1Of	cells,CD4+
R7370	T9268	T9267	arg1Of	cells,T
R7371	T9270	T9269	arg1Of	in,even
R7372	T9270	T9271	arg1Of	in,the
R7373	T9270	T9273	arg1Of	in,of
R7374	T9272	T9270	arg2Of	presence,in
R7375	T9275	T9270	arg3Of	acid,in
R7376	T9275	T9274	arg1Of	acid,retinoic
R7377	T9279	T9280	arg1Of	deficiency,in
R7378	T9279	T9285	arg1Of	deficiency,affects
R7379	T9282	T9280	arg2Of	binding,in
R7380	T9282	T9281	arg1Of	binding,Runx
R7381	T9282	T9283	arg1Of	binding,to
R7382	T9284	T9283	arg2Of	DNA,to
R7383	T9285	T9277	arg2Of	affects,demonstrating
R7384	T9285	T9278	arg1Of	affects,that
R7385	T9288	T9285	arg2Of	induction,affects
R7386	T9288	T9286	arg1Of	induction,the
R7387	T9288	T9287	arg1Of	induction,TGF-β
R7388	T9288	T9289	arg1Of	induction,of
R7389	T9288	T9291	arg1Of	induction,in
R7390	T9290	T9289	arg2Of	Foxp3,of
R7391	T9294	T9291	arg2Of	cells,in
R7392	T9294	T9292	arg1Of	cells,T
R7393	T9294	T9293	arg1Of	cells,reg
R7394	T9294	T9295	arg1Of	cells,(
R7395	T9298	T9295	arg2Of	A,(
R7396	T9298	T9296	arg1Of	A,Fig.
R7397	T9298	T9297	arg1Of	A,5
R7398	T9299	T9295	arg3Of	),(
R7399	T9300	T9301	arg1Of	There,was
R7400	T9301	T9304	arg1Of	was,in
R7401	T9301	T9309	arg1Of	was,when
R7402	T9303	T9301	arg2Of	difference,was
R7403	T9303	T9302	arg1Of	difference,no
R7404	T9306	T9304	arg2Of	induction,in
R7405	T9306	T9305	arg1Of	induction,the
R7406	T9306	T9307	arg1Of	induction,of
R7407	T9308	T9307	arg2Of	Foxp3,of
R7408	T9311	T9312	arg1Of	IL-4,and
R7409	T9312	T9310	arg1Of	and,endogenous
R7410	T9312	T9314	arg1Of	and,were
R7411	T9312	T9315	arg2Of	and,neutralized
R7412	T9313	T9312	arg2Of	IFN-γ,and
R7413	T9315	T9309	arg2Of	neutralized,when
R7414	T9315	T9314	arg2Of	neutralized,were
R7415	T9315	T9316	arg1Of	neutralized,(
R7416	T9318	T9316	arg2Of	S6,(
R7417	T9318	T9317	arg1Of	S6,Fig.
R7418	T9319	T9316	arg3Of	),(
R7419	T9321	T9320	arg1Of	importance,The
R7420	T9321	T9322	arg1Of	importance,of
R7421	T9321	T9340	arg1Of	importance,was
R7422	T9321	T9341	arg2Of	importance,examined
R7423	T9325	T9322	arg2Of	factors,of
R7424	T9325	T9323	arg1Of	factors,RUNX
R7425	T9325	T9324	arg1Of	factors,transcription
R7426	T9325	T9326	arg1Of	factors,for
R7427	T9329	T9328	arg1Of	vivo,in
R7428	T9330	T9326	arg2Of	conversion,for
R7429	T9330	T9327	arg1Of	conversion,the
R7430	T9330	T9329	arg1Of	conversion,vivo
R7431	T9330	T9331	arg1Of	conversion,of
R7432	T9330	T9336	arg1Of	conversion,into
R7433	T9335	T9331	arg2Of	cells,of
R7434	T9335	T9332	arg1Of	cells,naive
R7435	T9335	T9333	arg1Of	cells,CD4+
R7436	T9335	T9334	arg1Of	cells,T
R7437	T9339	T9336	arg2Of	cells,into
R7438	T9339	T9337	arg1Of	cells,iT
R7439	T9339	T9338	arg1Of	cells,reg
R7440	T9341	T9340	arg2Of	examined,was
R7441	T9343	T9342	arg1Of	CbfbF/F,Control
R7442	T9343	T9344	arg1Of	CbfbF/F,or
R7443	T9349	T9344	arg2Of	cells,or
R7444	T9349	T9345	arg1Of	cells,CbfbF/F
R7445	T9349	T9346	arg1Of	cells,CD4-cre
R7446	T9349	T9347	arg1Of	cells,naive
R7447	T9349	T9348	arg1Of	cells,T
R7448	T9349	T9350	arg1Of	cells,","
R7449	T9349	T9351	arg1Of	cells,harboring
R7450	T9354	T9352	arg1Of	allele,a
R7451	T9354	T9353	arg1Of	allele,Foxp3-IRES-GFP
R7452	T9354	T9355	arg1Of	allele,were
R7453	T9354	T9357	arg2Of	allele,transferred
R7454	T9357	T9351	arg2Of	transferred,harboring
R7455	T9357	T9355	arg2Of	transferred,were
R7456	T9357	T9356	arg1Of	transferred,adoptively
R7457	T9357	T9358	arg1Of	transferred,into
R7458	T9360	T9358	arg2Of	mice,into
R7459	T9360	T9359	arg1Of	mice,Rag2−/−
R7460	T9362	T9361	arg1Of	wk,6
R7461	T9363	T9362	arg1Of	later,wk
R7462	T9367	T9365	arg1Of	cells,CD4+
R7463	T9367	T9366	arg1Of	cells,T
R7464	T9367	T9368	arg1Of	cells,in
R7465	T9367	T9382	arg1Of	cells,were
R7466	T9367	T9383	arg2Of	cells,analyzed
R7467	T9369	T9370	arg1Of	spleen,","
R7468	T9370	T9375	arg1Of	",",and
R7469	T9373	T9370	arg2Of	node,","
R7470	T9373	T9371	arg1Of	node,mesenteric
R7471	T9373	T9372	arg1Of	node,lymph
R7472	T9375	T9368	arg2Of	and,in
R7473	T9375	T9374	arg1Of	and,","
R7474	T9377	T9375	arg2Of	propria,and
R7475	T9377	T9376	arg1Of	propria,lamina
R7476	T9377	T9378	arg1Of	propria,of
R7477	T9381	T9378	arg2Of	intestine,of
R7478	T9381	T9379	arg1Of	intestine,the
R7479	T9381	T9380	arg1Of	intestine,small
R7480	T9383	T9363	arg1Of	analyzed,later
R7481	T9383	T9364	arg1Of	analyzed,","
R7482	T9383	T9382	arg2Of	analyzed,were
R7483	T9383	T9384	arg1Of	analyzed,for
R7484	T9386	T9384	arg2Of	expression,for
R7485	T9386	T9385	arg1Of	expression,Foxp3-GFP
R7486	T9386	T9387	arg1Of	expression,(
R7487	T9390	T9387	arg2Of	B,(
R7488	T9390	T9388	arg1Of	B,Fig.
R7489	T9390	T9389	arg1Of	B,5
R7490	T9391	T9387	arg3Of	),(
R7491	T9392	T9393	arg1Of	There,was
R7492	T9396	T9395	arg1Of	lower,consistently
R7493	T9397	T9393	arg2Of	percentage,was
R7494	T9397	T9394	arg1Of	percentage,a
R7495	T9397	T9396	arg1Of	percentage,lower
R7496	T9397	T9398	arg1Of	percentage,of
R7497	T9397	T9402	arg1Of	percentage,that
R7498	T9397	T9403	arg1Of	percentage,had
R7499	T9397	T9404	arg1Of	percentage,developed
R7500	T9401	T9398	arg2Of	cells,of
R7501	T9401	T9399	arg1Of	cells,CD4+
R7502	T9401	T9400	arg1Of	cells,T
R7503	T9404	T9403	arg2Of	developed,had
R7504	T9406	T9404	arg2Of	expression,developed
R7505	T9406	T9405	arg1Of	expression,Foxp3
R7506	T9406	T9407	arg1Of	expression,in
R7507	T9406	T9415	arg1Of	expression,of
R7508	T9411	T9409	arg1Of	node,mesenteric
R7509	T9411	T9410	arg1Of	node,lymph
R7510	T9411	T9412	arg1Of	node,and
R7511	T9412	T9407	arg2Of	and,in
R7512	T9412	T9408	arg1Of	and,the
R7513	T9414	T9412	arg2Of	propria,and
R7514	T9414	T9413	arg1Of	propria,lamina
R7515	T9416	T9415	arg2Of	mice,of
R7516	T9416	T9417	arg2Of	mice,transferred
R7517	T9417	T9418	arg1Of	transferred,with
R7518	T9417	T9422	arg1Of	transferred,compared
R7519	T9421	T9418	arg2Of	cells,with
R7520	T9421	T9419	arg1Of	cells,CbfbF/F
R7521	T9421	T9420	arg1Of	cells,CD4-cre
R7522	T9423	T9422	arg2Of	with,compared
R7523	T9425	T9423	arg2Of	cells,with
R7524	T9425	T9424	arg1Of	cells,control
R7525	T9425	T9426	arg1Of	cells,(
R7526	T9427	T9428	arg1Of	Fig.,5
R7527	T9427	T9429	arg1Of	Fig.,","
R7528	T9429	T9431	arg1Of	",",and
R7529	T9430	T9429	arg2Of	B,","
R7530	T9431	T9426	arg2Of	and,(
R7531	T9432	T9431	arg2Of	C,and
R7532	T9433	T9426	arg3Of	),(
R7533	T9435	T9434	arg1Of	data,These
R7534	T9435	T9436	arg1Of	data,affirm
R7535	T9438	T9436	arg2Of	significance,affirm
R7536	T9438	T9437	arg1Of	significance,the
R7537	T9438	T9439	arg1Of	significance,of
R7538	T9438	T9442	arg1Of	significance,for
R7539	T9441	T9439	arg2Of	proteins,of
R7540	T9441	T9440	arg1Of	proteins,RUNX
R7541	T9445	T9444	arg1Of	vivo,in
R7542	T9446	T9442	arg2Of	generation,for
R7543	T9446	T9443	arg1Of	generation,the
R7544	T9446	T9445	arg1Of	generation,vivo
R7545	T9446	T9447	arg1Of	generation,of
R7546	T9451	T9447	arg2Of	cells,of
R7547	T9451	T9448	arg1Of	cells,CD4+
R7548	T9451	T9449	arg1Of	cells,Foxp3+
R7549	T9451	T9450	arg1Of	cells,T
R24111	T31442	T31441	arg2Of	capacity,Diminished
R24112	T31442	T31443	arg1Of	capacity,of
R24113	T31442	T31474	arg1Of	capacity,were
R24114	T31442	T31475	arg2Of	capacity,activated
R24115	T31448	T31443	arg2Of	cells,of
R24116	T31448	T31444	arg1Of	cells,Cbfb-deficient
R24117	T31448	T31445	arg1Of	cells,CD4-cre
R24118	T31448	T31446	arg1Of	cells,mice
R24119	T31448	T31447	arg1Of	cells,T
R24120	T31448	T31449	arg1Of	cells,in
R24121	T31451	T31449	arg2Of	generation,in
R24122	T31451	T31450	arg1Of	generation,the
R24123	T31451	T31452	arg1Of	generation,of
R24124	T31456	T31453	arg1Of	cells.,Foxp3+
R24125	T31456	T31454	arg1Of	cells.,CD4+
R24126	T31456	T31455	arg1Of	cells.,T
R24127	T31456	T31457	arg1Of	cells.,(
R24128	T31458	T31457	arg2Of	A,(
R24129	T31459	T31457	arg3Of	),(
R24130	T31465	T31452	arg2Of	cells,of
R24131	T31465	T31456	arg1Of	cells,cells.
R24132	T31465	T31460	arg1Of	cells,FACS-purified
R24133	T31465	T31461	arg1Of	cells,naive
R24134	T31465	T31462	arg1Of	cells,CD4+
R24135	T31465	T31463	arg1Of	cells,CD8−
R24136	T31465	T31464	arg1Of	cells,T
R24137	T31465	T31466	arg1Of	cells,from
R24138	T31468	T31469	arg1Of	CD4-cre,and
R24139	T31469	T31467	arg1Of	and,CbfbF/F
R24140	T31470	T31469	arg2Of	control,and
R24141	T31473	T31466	arg2Of	mice,from
R24142	T31473	T31468	arg1Of	mice,CD4-cre
R24143	T31473	T31470	arg1Of	mice,control
R24144	T31473	T31471	arg1Of	mice,CbfbF/+
R24145	T31473	T31472	arg1Of	mice,CD4-cre
R24146	T31475	T31474	arg2Of	activated,were
R24147	T31475	T31477	arg1Of	activated,vitro
R24148	T31475	T31478	arg1Of	activated,with
R24149	T31477	T31476	arg1Of	vitro,in
R24150	T31480	T31479	arg1Of	mAb,anti-CD3/28
R24151	T31480	T31481	arg1Of	mAb,","
R24152	T31481	T31485	arg1Of	",",","
R24153	T31481	T31486	arg1Of	",",±
R24154	T31481	T31495	arg1Of	",",and
R24155	T31484	T31481	arg2Of	IL-2,","
R24156	T31484	T31482	arg1Of	IL-2,50
R24157	T31484	T31483	arg1Of	IL-2,U/ml
R24158	T31490	T31486	arg2Of	acid,±
R24159	T31490	T31487	arg1Of	acid,10
R24160	T31490	T31488	arg1Of	acid,nM
R24161	T31490	T31489	arg1Of	acid,retinoic
R24162	T31490	T31491	arg1Of	acid,(
R24163	T31492	T31491	arg2Of	RA,(
R24164	T31493	T31491	arg3Of	),(
R24165	T31495	T31478	arg2Of	and,with
R24166	T31495	T31494	arg1Of	and,","
R24167	T31497	T31495	arg2Of	concentrations,and
R24168	T31497	T31496	arg1Of	concentrations,increasing
R24169	T31497	T31498	arg1Of	concentrations,of
R24170	T31499	T31498	arg2Of	TGF-β,of
R24171	T31502	T31500	arg2Of	d,After
R24172	T31502	T31501	arg1Of	d,3
R24173	T31502	T31503	arg1Of	d,in
R24174	T31504	T31503	arg2Of	culture,in
R24175	T31507	T31506	arg1Of	cells,the
R24176	T31507	T31508	arg1Of	cells,were
R24177	T31507	T31509	arg2Of	cells,restimulated
R24178	T31507	T31517	arg2Of	cells,analyzed
R24179	T31509	T31510	arg1Of	restimulated,with
R24180	T31509	T31515	arg1Of	restimulated,and
R24181	T31511	T31510	arg2Of	PMA,with
R24182	T31513	T31510	arg3Of	ionomycin,with
R24183	T31513	T31512	arg1Of	ionomycin,+
R24184	T31515	T31500	arg1Of	and,After
R24185	T31515	T31505	arg1Of	and,","
R24186	T31515	T31508	arg2Of	and,were
R24187	T31515	T31514	arg1Of	and,","
R24188	T31517	T31515	arg2Of	analyzed,and
R24189	T31517	T31516	arg1Of	analyzed,then
R24190	T31517	T31518	arg1Of	analyzed,for
R24191	T31520	T31521	arg1Of	Foxp3,and
R24192	T31522	T31521	arg2Of	IFN-γ,and
R24193	T31523	T31518	arg2Of	expression,for
R24194	T31523	T31519	arg1Of	expression,intracellular
R24195	T31523	T31520	arg1Of	expression,Foxp3
R24196	T31523	T31522	arg1Of	expression,IFN-γ
R24197	T31524	T31525	arg1Of	One,of
R24198	T31524	T31528	arg1Of	One,is
R24199	T31527	T31525	arg2Of	experiments,of
R24200	T31527	T31526	arg1Of	experiments,five
R24201	T31529	T31528	arg2Of	shown.,is
R24202	T31529	T31549	modOf	shown.,were
R24203	T31531	T31530	arg2Of	B,(
R24204	T31532	T31530	arg3Of	),(
R24205	T31536	T31530	arg1Of	cells,(
R24206	T31536	T31533	arg1Of	cells,Naive
R24207	T31536	T31534	arg1Of	cells,CD4+
R24208	T31536	T31535	arg1Of	cells,T
R24209	T31536	T31537	arg1Of	cells,from
R24210	T31536	T31543	arg1Of	cells,(
R24211	T31536	T31549	arg1Of	cells,were
R24212	T31536	T31551	arg2Of	cells,transferred
R24213	T31539	T31540	arg1Of	CD4-cre,or
R24214	T31541	T31540	arg2Of	control,or
R24215	T31542	T31537	arg2Of	mice,from
R24216	T31542	T31538	arg1Of	mice,Cbfb
R24217	T31542	T31539	arg1Of	mice,CD4-cre
R24218	T31542	T31541	arg1Of	mice,control
R24219	T31544	T31543	arg2Of	harboring,(
R24220	T31547	T31544	arg2Of	allele,harboring
R24221	T31547	T31545	arg1Of	allele,a
R24222	T31547	T31546	arg1Of	allele,Foxp3-IRES-GFP
R24223	T31548	T31543	arg3Of	),(
R24224	T31551	T31549	arg2Of	transferred,were
R24225	T31551	T31550	arg1Of	transferred,adoptively
R24226	T31551	T31552	arg1Of	transferred,into
R24227	T31554	T31552	arg2Of	mice,into
R24228	T31554	T31553	arg1Of	mice,Rag-deficient
R24229	T31554	T31555	arg1Of	mice,(
R24230	T31559	T31555	arg2Of	cells,(
R24231	T31559	T31556	arg1Of	cells,5
R24232	T31559	T31557	arg1Of	cells,×
R24233	T31559	T31558	arg1Of	cells,106
R24234	T31559	T31560	arg1Of	cells,per
R24235	T31561	T31560	arg2Of	transfer,per
R24236	T31562	T31555	arg3Of	),(
R24237	T31564	T31563	arg1Of	wk,6
R24238	T31565	T31564	arg1Of	later,wk
R24239	T31568	T31567	arg1Of	cells,TCRβ+CD4+
R24240	T31568	T31569	arg1Of	cells,from
R24241	T31568	T31572	arg1Of	cells,","
R24242	T31568	T31580	arg1Of	cells,and
R24243	T31571	T31569	arg2Of	spleen,from
R24244	T31571	T31570	arg1Of	spleen,the
R24245	T31575	T31572	arg2Of	node,","
R24246	T31575	T31573	arg1Of	node,mesenteric
R24247	T31575	T31574	arg1Of	node,lymph
R24248	T31575	T31576	arg1Of	node,(
R24249	T31577	T31576	arg2Of	MLN,(
R24250	T31578	T31576	arg3Of	),(
R24251	T31580	T31579	arg1Of	and,","
R24252	T31580	T31590	arg1Of	and,were
R24253	T31580	T31591	arg2Of	and,analyzed
R24254	T31582	T31580	arg2Of	propria,and
R24255	T31582	T31581	arg1Of	propria,lamina
R24256	T31582	T31583	arg1Of	propria,of
R24257	T31586	T31583	arg2Of	intestine,of
R24258	T31586	T31584	arg1Of	intestine,the
R24259	T31586	T31585	arg1Of	intestine,small
R24260	T31586	T31587	arg1Of	intestine,(
R24261	T31588	T31587	arg2Of	LP,(
R24262	T31589	T31587	arg3Of	),(
R24263	T31591	T31565	arg1Of	analyzed,later
R24264	T31591	T31566	arg1Of	analyzed,","
R24265	T31591	T31590	arg2Of	analyzed,were
R24266	T31591	T31592	arg1Of	analyzed,for
R24267	T31594	T31592	arg2Of	expression,for
R24268	T31594	T31593	arg1Of	expression,Foxp3-GFP
R24269	T31595	T31596	arg1Of	Results,from
R24270	T31595	T31610	arg1Of	Results,are
R24271	T31595	T31611	arg2Of	Results,shown
R24272	T31597	T31596	arg2Of	one,from
R24273	T31597	T31598	arg1Of	one,of
R24274	T31597	T31607	arg1Of	one,with
R24275	T31600	T31599	arg1Of	CbfbF/F,four
R24276	T31600	T31601	arg1Of	CbfbF/F,CD4-cre
R24277	T31600	T31603	arg1Of	CbfbF/F,control
R24278	T31601	T31602	arg1Of	CD4-cre,and
R24279	T31603	T31602	arg2Of	control,and
R24280	T31604	T31600	arg1Of	CbfbF/+,CbfbF/F
R24281	T31606	T31598	arg2Of	mice,of
R24282	T31606	T31604	arg1Of	mice,CbfbF/+
R24283	T31606	T31605	arg1Of	mice,CD4-cre
R24284	T31609	T31607	arg2Of	findings,with
R24285	T31609	T31608	arg1Of	findings,same
R24286	T31611	T31610	arg2Of	shown,are
R24287	T31613	T31612	arg1Of	data,The
R24288	T31613	T31614	arg1Of	data,from
R24289	T31613	T31619	arg1Of	data,is
R24290	T31613	T31620	arg2Of	data,shown
R24291	T31616	T31614	arg2Of	sets,from
R24292	T31616	T31615	arg1Of	sets,four
R24293	T31616	T31617	arg1Of	sets,of
R24294	T31618	T31617	arg2Of	mice,of
R24295	T31620	T31619	arg2Of	shown,is
R24296	T31620	T31621	arg1Of	shown,in
R24297	T31623	T31622	arg1Of	Statistical,C.
R24298	T31624	T31623	arg1Of	analysis,Statistical
R24299	T31624	T31625	arg1Of	analysis,was
R24300	T31624	T31626	arg2Of	analysis,performed
R24301	T31626	T31621	arg2Of	performed,in
R24302	T31626	T31625	arg2Of	performed,was
R24303	T31626	T31627	arg1Of	performed,with
R24304	T31630	T31628	arg1Of	test.,Mann-Whitney
R24305	T31630	T31629	arg1Of	test.,U
R24306	T31630	T31631	arg1Of	test.,*
R24307	T31631	T31632	arg1Of	*,","
R24308	T31633	T31632	arg2Of	P,","
R24309	T31633	T31634	arg1Of	P,<
R24310	T31635	T31627	arg2Of	0.05,with
R24311	T31635	T31630	arg1Of	0.05,test.
R24312	T31635	T31636	arg1Of	0.05,between
R24313	T31637	T31636	arg2Of	groups,between
R7140	T9049	T9050	arg1Of	Role,of
R7141	T9049	T9052	arg1Of	Role,in
R7142	T9051	T9050	arg2Of	CBFβ,of
R7143	T9054	T9052	arg2Of	induction,in
R7144	T9054	T9053	arg1Of	induction,the
R7145	T9054	T9055	arg1Of	induction,of
R7146	T9056	T9055	arg2Of	Foxp3,of
R7147	T9057	T9058	arg1Of	CBFβ,","
R7148	T9057	T9067	arg1Of	CBFβ,stabilizes
R7149	T9057	T9069	arg1Of	CBFβ,increases
R7150	T9061	T9058	arg2Of	cofactor,","
R7151	T9061	T9059	arg1Of	cofactor,a
R7152	T9061	T9060	arg1Of	cofactor,common
R7153	T9061	T9062	arg1Of	cofactor,of
R7154	T9065	T9062	arg2Of	proteins,of
R7155	T9065	T9063	arg1Of	proteins,all
R7156	T9065	T9064	arg1Of	proteins,RUNX
R7157	T9067	T9068	arg1Of	stabilizes,and
R7158	T9068	T9066	arg1Of	and,","
R7159	T9069	T9068	arg2Of	increases,and
R7160	T9071	T9067	arg2Of	binding,stabilizes
R7161	T9071	T9069	arg2Of	binding,increases
R7162	T9071	T9070	arg1Of	binding,the
R7163	T9071	T9072	arg1Of	binding,of
R7164	T9071	T9076	modOf	binding,to
R7165	T9075	T9072	arg2Of	domain,of
R7166	T9075	T9073	arg1Of	domain,the
R7167	T9075	T9074	arg1Of	domain,runt
R7168	T9077	T9076	arg1Of	target,to
R7169	T9079	T9077	arg2Of	sequences,target
R7170	T9079	T9078	arg1Of	sequences,DNA
R7171	T9081	T9080	arg1Of	target,To
R7172	T9084	T9081	arg2Of	proteins,target
R7173	T9084	T9082	arg1Of	proteins,all
R7174	T9084	T9083	arg1Of	proteins,Runx
R7175	T9084	T9085	arg1Of	proteins,that
R7176	T9084	T9086	arg1Of	proteins,might
R7177	T9084	T9087	arg1Of	proteins,be

bionlp-st-ge-2016-coref

Id	Subject	Object	Predicate	Lexical cue
T9452	938-942	Anaphor	denotes	this
T9453	867-874	Antecedent	denotes	induced
R7550	T9452	T9453	boundBy	this,induced

bionlp-st-ge-2016-spacy-parsed

Id	Subject	Object	Predicate	Lexical cue
T9549	0-4	NN	denotes	Role
T9550	5-7	IN	denotes	of
T9551	8-12	NNP	denotes	CBFβ
T9552	13-15	IN	denotes	in
T9553	16-19	DT	denotes	the
T9554	20-29	NN	denotes	induction
T9555	30-32	IN	denotes	of
T9556	33-38	NNP	denotes	Foxp3
T9557	39-43	NNP	denotes	CBFβ
T9558	43-44	,	denotes	,
T9559	45-46	DT	denotes	a
T9560	47-53	JJ	denotes	common
T9561	54-62	NN	denotes	cofactor
T9562	63-65	IN	denotes	of
T9563	66-69	DT	denotes	all
T9564	70-74	NNP	denotes	RUNX
T9565	75-83	NNS	denotes	proteins
T9566	83-84	,	denotes	,
T9567	85-95	VBZ	denotes	stabilizes
T9568	96-99	CC	denotes	and
T9569	100-109	VBZ	denotes	increases
T9570	110-113	DT	denotes	the
T9571	114-121	JJ	denotes	binding
T9572	122-124	IN	denotes	of
T9573	125-128	DT	denotes	the
T9574	129-133	NN	denotes	runt
T9575	134-140	NN	denotes	domain
T9576	141-143	TO	denotes	to
T9577	144-150	VB	denotes	target
T9578	151-154	NNP	denotes	DNA
T9579	155-164	NNS	denotes	sequences
T9580	164-165	.	denotes	.
T9581	166-168	TO	denotes	To
T9582	169-175	VB	denotes	target
T9583	176-179	DT	denotes	all
T9584	180-184	NNP	denotes	Runx
T9585	185-193	NNS	denotes	proteins
T9586	194-198	WDT	denotes	that
T9587	199-204	MD	denotes	might
T9588	205-207	VB	denotes	be
T9589	208-216	VBN	denotes	involved
T9590	217-219	IN	denotes	in
T9591	220-223	DT	denotes	the
T9592	224-233	NN	denotes	induction
T9593	234-236	IN	denotes	of
T9594	237-242	NNP	denotes	Foxp3
T9595	242-243	,	denotes	,
T9596	244-246	PRP	denotes	we
T9597	247-251	VBD	denotes	used
T9598	252-256	NNS	denotes	mice
T9599	257-259	IN	denotes	in
T9600	260-265	WDT	denotes	which
T9601	266-278	JJ	denotes	loxP-flanked
T9602	279-283	NNP	denotes	Cbfb
T9603	284-291	NNS	denotes	alleles
T9604	292-296	VBD	denotes	were
T9605	297-308	VBN	denotes	inactivated
T9606	309-311	IN	denotes	in
T9607	312-313	NNP	denotes	T
T9608	314-319	NNS	denotes	cells
T9609	320-327	IN	denotes	through
T9610	328-338	NN	denotes	expression
T9611	339-341	IN	denotes	of
T9612	342-343	DT	denotes	a
T9613	344-351	JJ	denotes	CD4-cre
T9614	352-361	NN	denotes	transgene
T9615	361-362	.	denotes	.
T9616	363-371	NNP	denotes	Retinoic
T9617	372-376	NN	denotes	acid
T9618	377-380	CC	denotes	and
T9619	381-386	JJ	denotes	TGF-β
T9620	387-396	NN	denotes	synergize
T9621	397-399	IN	denotes	in
T9622	400-403	DT	denotes	the
T9623	404-413	NN	denotes	induction
T9624	414-416	IN	denotes	of
T9625	417-422	NNP	denotes	Foxp3
T9626	423-425	IN	denotes	in
T9627	426-431	JJ	denotes	naive
T9628	432-433	NNP	denotes	T
T9629	434-439	NNS	denotes	cells
T9630	440-441	-LRB-	denotes	(
T9631	441-445	NNP	denotes	Kang
T9632	446-448	FW	denotes	et
T9633	449-452	FW	denotes	al.
T9634	452-453	,	denotes	,
T9635	454-458	CD	denotes	2007
T9636	458-459	-RRB-	denotes	)
T9637	459-460	.	denotes	.
T9638	461-463	TO	denotes	To
T9639	464-475	VB	denotes	investigate
T9640	476-483	IN	denotes	whether
T9641	484-497	JJ	denotes	Runx-mediated
T9642	498-507	NN	denotes	induction
T9643	508-510	IN	denotes	of
T9644	511-516	NNP	denotes	Foxp3
T9645	517-519	VBZ	denotes	is
T9646	520-529	JJ	denotes	dependent
T9647	530-532	IN	denotes	on
T9648	533-536	DT	denotes	the
T9649	537-547	NN	denotes	expression
T9650	548-550	IN	denotes	of
T9651	551-555	NNP	denotes	CBFβ
T9652	555-556	,	denotes	,
T9653	557-562	JJ	denotes	naive
T9654	563-566	NNP	denotes	CD4
T9655	566-567	NNP	denotes	+
T9656	568-571	NNP	denotes	CD8
T9657	571-572	VBD	denotes	−
T9658	573-574	NNP	denotes	T
T9659	575-580	NNS	denotes	cells
T9660	581-585	IN	denotes	from
T9661	586-593	NNP	denotes	CbfbF/F
T9662	594-601	NNP	denotes	CD4-cre
T9663	602-605	CC	denotes	and
T9664	606-613	NN	denotes	control
T9665	614-619	NNP	denotes	CbfbF
T9666	619-620	NNP	denotes	/
T9667	620-621	VBD	denotes	+
T9668	622-629	JJ	denotes	CD4-cre
T9669	630-634	NNS	denotes	mice
T9670	635-639	VBD	denotes	were
T9671	640-650	VBN	denotes	stimulated
T9672	651-655	IN	denotes	with
T9673	656-664	JJ	denotes	anti-CD3
T9674	664-665	NN	denotes	/
T9675	665-667	CD	denotes	28
T9676	668-672	NNS	denotes	mAbs
T9677	672-673	,	denotes	,
T9678	674-682	JJ	denotes	retinoic
T9679	683-687	NN	denotes	acid
T9680	687-688	,	denotes	,
T9681	689-692	CC	denotes	and
T9682	693-703	VBG	denotes	increasing
T9683	704-718	NNS	denotes	concentrations
T9684	719-721	IN	denotes	of
T9685	722-727	NNP	denotes	TGF-β
T9686	727-728	.	denotes	.
T9687	729-734	IN	denotes	After
T9688	735-736	CD	denotes	3
T9689	737-738	LS	denotes	d
T9690	739-741	IN	denotes	in
T9691	742-749	NN	denotes	culture
T9692	749-750	,	denotes	,
T9693	751-754	DT	denotes	the
T9694	755-760	NNS	denotes	cells
T9695	761-765	VBD	denotes	were
T9696	766-778	VBN	denotes	restimulated
T9697	779-783	IN	denotes	with
T9698	784-787	NNP	denotes	PMA
T9699	788-791	CC	denotes	and
T9700	792-801	NN	denotes	ionomycin
T9701	802-805	CC	denotes	and
T9702	806-814	VBD	denotes	analyzed
T9703	815-818	IN	denotes	for
T9704	819-832	JJ	denotes	intracellular
T9705	833-838	NNP	denotes	Foxp3
T9706	839-842	CC	denotes	and
T9707	843-848	NNP	denotes	IFN-γ
T9708	849-859	NN	denotes	expression
T9709	859-860	.	denotes	.
T9710	861-866	JJ	denotes	TGF-β
T9711	867-874	JJ	denotes	induced
T9712	875-880	NN	denotes	Foxp3
T9713	881-883	IN	denotes	in
T9714	884-889	NNP	denotes	CbfbF
T9715	889-890	NNP	denotes	/
T9716	890-891	VBD	denotes	+
T9717	892-899	JJ	denotes	CD4-cre
T9718	900-905	NNS	denotes	cells
T9719	906-908	IN	denotes	in
T9720	909-910	DT	denotes	a
T9721	911-915	NN	denotes	dose
T9722	916-925	JJ	denotes	dependent
T9723	926-932	NN	denotes	manner
T9724	932-933	,	denotes	,
T9725	934-937	CC	denotes	and
T9726	938-942	DT	denotes	this
T9727	943-946	VBD	denotes	was
T9728	947-960	RB	denotes	significantly
T9729	961-968	VBN	denotes	reduced
T9730	969-971	IN	denotes	in
T9731	972-979	NNP	denotes	CbfbF/F
T9732	980-987	NNP	denotes	CD4-cre
T9733	988-993	NNS	denotes	cells
T9734	993-994	.	denotes	.
T9735	995-1003	NNP	denotes	Retinoic
T9736	1004-1008	NN	denotes	acid
T9737	1009-1017	JJ	denotes	enhanced
T9738	1018-1023	JJ	denotes	Foxp3
T9739	1024-1034	NN	denotes	expression
T9740	1035-1039	RB	denotes	even
T9741	1040-1042	IN	denotes	in
T9742	1043-1045	CD	denotes	20
T9743	1046-1051	NN	denotes	pg/ml
T9744	1052-1054	IN	denotes	of
T9745	1055-1060	NNP	denotes	TGF-β
T9746	1061-1064	CC	denotes	and
T9747	1065-1069	JJR	denotes	more
T9748	1070-1074	IN	denotes	than
T9749	1075-1077	CD	denotes	95
T9750	1077-1078	NN	denotes	%
T9751	1079-1081	IN	denotes	of
T9752	1082-1085	DT	denotes	the
T9753	1086-1089	NNP	denotes	CD4
T9754	1089-1090	CD	denotes	+
T9755	1091-1092	NNP	denotes	T
T9756	1093-1098	NNS	denotes	cells
T9757	1099-1103	IN	denotes	from
T9758	1104-1109	NNP	denotes	CbfbF
T9759	1109-1110	NNP	denotes	/
T9760	1110-1111	VBD	denotes	+
T9761	1112-1119	JJ	denotes	CD4-cre
T9762	1120-1124	NNS	denotes	mice
T9763	1125-1131	VBD	denotes	became
T9764	1132-1137	JJ	denotes	Foxp3
T9765	1137-1138	NN	denotes	+
T9766	1139-1141	IN	denotes	in
T9767	1142-1145	CD	denotes	100
T9768	1146-1149	CC	denotes	and
T9769	1150-1153	CD	denotes	500
T9770	1154-1159	JJ	denotes	pg/ml
T9771	1160-1165	JJ	denotes	TGF-β
T9772	1166-1171	NNS	denotes	doses
T9773	1171-1172	.	denotes	.
T9774	1173-1176	DT	denotes	The
T9775	1177-1186	NN	denotes	induction
T9776	1187-1189	IN	denotes	of
T9777	1190-1195	NNP	denotes	Foxp3
T9778	1196-1199	VBD	denotes	was
T9779	1200-1205	RB	denotes	again
T9780	1206-1219	RB	denotes	significantly
T9781	1220-1225	JJR	denotes	lower
T9782	1226-1228	IN	denotes	in
T9783	1229-1236	NNP	denotes	CbfbF/F
T9784	1237-1244	NNP	denotes	CD4-cre
T9785	1245-1248	NNP	denotes	CD4
T9786	1248-1249	VBD	denotes	+
T9787	1250-1251	NNP	denotes	T
T9788	1252-1257	NNS	denotes	cells
T9789	1258-1262	RB	denotes	even
T9790	1263-1265	IN	denotes	in
T9791	1266-1269	DT	denotes	the
T9792	1270-1278	NN	denotes	presence
T9793	1279-1281	IN	denotes	of
T9794	1282-1290	JJ	denotes	retinoic
T9795	1291-1295	NN	denotes	acid
T9796	1295-1296	,	denotes	,
T9797	1297-1310	VBG	denotes	demonstrating
T9798	1311-1315	IN	denotes	that
T9799	1316-1326	NN	denotes	deficiency
T9800	1327-1329	IN	denotes	in
T9801	1330-1334	NNP	denotes	Runx
T9802	1335-1342	JJ	denotes	binding
T9803	1343-1345	TO	denotes	to
T9804	1346-1349	NNP	denotes	DNA
T9805	1350-1357	VBZ	denotes	affects
T9806	1358-1361	DT	denotes	the
T9807	1362-1367	JJ	denotes	TGF-β
T9808	1368-1377	NN	denotes	induction
T9809	1378-1380	IN	denotes	of
T9810	1381-1386	NNP	denotes	Foxp3
T9811	1387-1389	IN	denotes	in
T9812	1390-1391	NNP	denotes	T
T9813	1392-1395	NN	denotes	reg
T9814	1396-1401	NNS	denotes	cells
T9815	1402-1403	-LRB-	denotes	(
T9816	1403-1407	NNP	denotes	Fig.
T9817	1408-1409	CD	denotes	5
T9818	1410-1411	NNP	denotes	A
T9819	1411-1412	-RRB-	denotes	)
T9820	1412-1413	.	denotes	.
T9821	1414-1419	EX	denotes	There
T9822	1420-1423	VBD	denotes	was
T9823	1424-1426	DT	denotes	no
T9824	1427-1437	NN	denotes	difference
T9825	1438-1440	IN	denotes	in
T9826	1441-1444	DT	denotes	the
T9827	1445-1454	NN	denotes	induction
T9828	1455-1457	IN	denotes	of
T9829	1458-1463	CD	denotes	Foxp3
T9830	1464-1468	WRB	denotes	when
T9831	1469-1479	JJ	denotes	endogenous
T9832	1480-1484	NN	denotes	IL-4
T9833	1485-1488	CC	denotes	and
T9834	1489-1494	JJ	denotes	IFN-γ
T9835	1495-1499	VBD	denotes	were
T9836	1500-1511	VBN	denotes	neutralized
T9837	1512-1513	-LRB-	denotes	(
T9838	1513-1516	NNP	denotes	Fig
T9839	1516-1517	.	denotes	.
T9840	1518-1520	CD	denotes	S6
T9841	1520-1521	-RRB-	denotes	)
T9842	1521-1522	.	denotes	.
T9843	2607-2610	DT	denotes	The
T9844	2611-2621	NN	denotes	importance
T9845	2622-2624	IN	denotes	of
T9846	2625-2629	NNP	denotes	RUNX
T9847	2630-2643	NN	denotes	transcription
T9848	2644-2651	NNS	denotes	factors
T9849	2652-2655	IN	denotes	for
T9850	2656-2659	DT	denotes	the
T9851	2660-2662	IN	denotes	in
T9852	2663-2667	NN	denotes	vivo
T9853	2668-2678	NN	denotes	conversion
T9854	2679-2681	IN	denotes	of
T9855	2682-2687	JJ	denotes	naive
T9856	2688-2691	NNP	denotes	CD4
T9857	2691-2692	CD	denotes	+
T9858	2693-2694	NNP	denotes	T
T9859	2695-2700	NNS	denotes	cells
T9860	2701-2705	IN	denotes	into
T9861	2706-2708	NNP	denotes	iT
T9862	2709-2712	NN	denotes	reg
T9863	2713-2718	NNS	denotes	cells
T9864	2719-2722	VBD	denotes	was
T9865	2723-2731	VBN	denotes	examined
T9866	2731-2732	.	denotes	.
T9867	2733-2740	NNP	denotes	Control
T9868	2741-2748	NNP	denotes	CbfbF/F
T9869	2749-2751	CC	denotes	or
T9870	2752-2759	NNP	denotes	CbfbF/F
T9871	2760-2767	NNP	denotes	CD4-cre
T9872	2768-2773	JJ	denotes	naive
T9873	2774-2775	NNP	denotes	T
T9874	2776-2781	NNS	denotes	cells
T9875	2781-2782	,	denotes	,
T9876	2783-2792	VBG	denotes	harboring
T9877	2793-2794	DT	denotes	a
T9878	2795-2809	JJ	denotes	Foxp3-IRES-GFP
T9879	2810-2816	NN	denotes	allele
T9880	2817-2821	VBD	denotes	were
T9881	2822-2832	RB	denotes	adoptively
T9882	2833-2844	VBN	denotes	transferred
T9883	2845-2849	IN	denotes	into
T9884	2850-2854	NNP	denotes	Rag2
T9885	2854-2855	NNP	denotes	−
T9886	2855-2856	VBD	denotes	/
T9887	2856-2857	CD	denotes	−
T9888	2858-2862	NNS	denotes	mice
T9889	2862-2863	.	denotes	.
T9890	2864-2865	CD	denotes	6
T9891	2866-2868	NN	denotes	wk
T9892	2869-2874	RB	denotes	later
T9893	2874-2875	,	denotes	,
T9894	2876-2879	NNP	denotes	CD4
T9895	2879-2880	NNP	denotes	+
T9896	2881-2882	NNP	denotes	T
T9897	2883-2888	NNS	denotes	cells
T9898	2889-2891	IN	denotes	in
T9899	2892-2898	NN	denotes	spleen
T9900	2898-2899	,	denotes	,
T9901	2900-2910	JJ	denotes	mesenteric
T9902	2911-2916	NN	denotes	lymph
T9903	2917-2921	NN	denotes	node
T9904	2921-2922	,	denotes	,
T9905	2923-2926	CC	denotes	and
T9906	2927-2933	NN	denotes	lamina
T9907	2934-2941	NN	denotes	propria
T9908	2942-2944	IN	denotes	of
T9909	2945-2948	DT	denotes	the
T9910	2949-2954	JJ	denotes	small
T9911	2955-2964	JJ	denotes	intestine
T9912	2965-2969	VBD	denotes	were
T9913	2970-2978	VBN	denotes	analyzed
T9914	2979-2982	IN	denotes	for
T9915	2983-2992	JJ	denotes	Foxp3-GFP
T9916	2993-3003	NN	denotes	expression
T9917	3004-3005	-LRB-	denotes	(
T9918	3005-3009	FW	denotes	Fig.
T9919	3010-3011	CD	denotes	5
T9920	3012-3013	NNP	denotes	B
T9921	3013-3014	-RRB-	denotes	)
T9922	3014-3015	.	denotes	.
T9923	3016-3021	EX	denotes	There
T9924	3022-3025	VBD	denotes	was
T9925	3026-3027	DT	denotes	a
T9926	3028-3040	RB	denotes	consistently
T9927	3041-3046	JJR	denotes	lower
T9928	3047-3057	NN	denotes	percentage
T9929	3058-3060	IN	denotes	of
T9930	3061-3064	CD	denotes	CD4
T9931	3064-3065	CD	denotes	+
T9932	3066-3067	NNP	denotes	T
T9933	3068-3073	NNS	denotes	cells
T9934	3074-3078	WDT	denotes	that
T9935	3079-3082	VBD	denotes	had
T9936	3083-3092	VBN	denotes	developed
T9937	3093-3098	JJ	denotes	Foxp3
T9938	3099-3109	NN	denotes	expression
T9939	3110-3112	IN	denotes	in
T9940	3113-3116	DT	denotes	the
T9941	3117-3127	JJ	denotes	mesenteric
T9942	3128-3133	NN	denotes	lymph
T9943	3134-3138	NN	denotes	node
T9944	3139-3142	CC	denotes	and
T9945	3143-3149	NN	denotes	lamina
T9946	3150-3157	NN	denotes	propria
T9947	3158-3160	IN	denotes	of
T9948	3161-3165	NNS	denotes	mice
T9949	3166-3177	VBN	denotes	transferred
T9950	3178-3182	IN	denotes	with
T9951	3183-3190	NNP	denotes	CbfbF/F
T9952	3191-3198	NNP	denotes	CD4-cre
T9953	3199-3204	NNS	denotes	cells
T9954	3205-3213	VBN	denotes	compared
T9955	3214-3218	IN	denotes	with
T9956	3219-3226	NN	denotes	control
T9957	3227-3232	NNS	denotes	cells
T9958	3233-3234	-LRB-	denotes	(
T9959	3234-3238	JJ	denotes	Fig.
T9960	3239-3240	CD	denotes	5
T9961	3240-3241	,	denotes	,
T9962	3242-3243	NNP	denotes	B
T9963	3244-3247	CC	denotes	and
T9964	3248-3249	NNP	denotes	C
T9965	3249-3250	-RRB-	denotes	)
T9966	3250-3251	.	denotes	.
T9967	3252-3257	DT	denotes	These
T9968	3258-3262	NNS	denotes	data
T9969	3263-3269	VBP	denotes	affirm
T9970	3270-3273	DT	denotes	the
T9971	3274-3286	NN	denotes	significance
T9972	3287-3289	IN	denotes	of
T9973	3290-3294	NNP	denotes	RUNX
T9974	3295-3303	NNS	denotes	proteins
T9975	3304-3307	IN	denotes	for
T9976	3308-3311	DT	denotes	the
T9977	3312-3314	IN	denotes	in
T9978	3315-3319	NN	denotes	vivo
T9979	3320-3330	NN	denotes	generation
T9980	3331-3333	IN	denotes	of
T9981	3334-3337	NNP	denotes	CD4
T9982	3337-3338	NNP	denotes	+
T9983	3339-3344	NNP	denotes	Foxp3
T9984	3344-3345	VBD	denotes	+
T9985	3346-3347	NNP	denotes	T
T9986	3348-3353	NNS	denotes	cells
T9987	3353-3354	.	denotes	.
T31677	1534-1544	VBN	denotes	Diminished
T31678	1545-1553	NN	denotes	capacity
T31679	1554-1556	IN	denotes	of
T31680	1557-1571	JJ	denotes	Cbfb-deficient
T31681	1572-1579	JJ	denotes	CD4-cre
T31682	1580-1584	NNS	denotes	mice
T31683	1585-1586	VBP	denotes	T
T31684	1587-1592	NNS	denotes	cells
T31685	1593-1595	IN	denotes	in
T31686	1596-1599	DT	denotes	the
T31687	1600-1610	NN	denotes	generation
T31688	1611-1613	IN	denotes	of
T31689	1614-1619	NNP	denotes	Foxp3
T31690	1619-1620	NNP	denotes	+
T31691	1621-1624	NNP	denotes	CD4
T31692	1624-1625	VBD	denotes	+
T31693	1626-1627	NNP	denotes	T
T31694	1628-1633	NNS	denotes	cells
T31695	1633-1634	.	denotes	.
T31696	1635-1636	-LRB-	denotes	(
T31697	1636-1637	NNP	denotes	A
T31698	1637-1638	-RRB-	denotes	)
T31699	1639-1652	JJ	denotes	FACS-purified
T31700	1653-1658	JJ	denotes	naive
T31701	1659-1662	NNP	denotes	CD4
T31702	1662-1663	NNP	denotes	+
T31703	1664-1667	NNP	denotes	CD8
T31704	1667-1668	VBD	denotes	−
T31705	1669-1670	NNP	denotes	T
T31706	1671-1676	NNS	denotes	cells
T31707	1677-1681	IN	denotes	from
T31708	1682-1689	NNP	denotes	CbfbF/F
T31709	1690-1697	NNP	denotes	CD4-cre
T31710	1698-1701	CC	denotes	and
T31711	1702-1709	NN	denotes	control
T31712	1710-1715	NNP	denotes	CbfbF
T31713	1715-1716	NNP	denotes	/
T31714	1716-1717	VBD	denotes	+
T31715	1718-1725	JJ	denotes	CD4-cre
T31716	1726-1730	NNS	denotes	mice
T31717	1731-1735	VBD	denotes	were
T31718	1736-1745	VBN	denotes	activated
T31719	1746-1748	IN	denotes	in
T31720	1749-1754	NN	denotes	vitro
T31721	1755-1759	IN	denotes	with
T31722	1760-1768	JJ	denotes	anti-CD3
T31723	1768-1769	NN	denotes	/
T31724	1769-1771	CD	denotes	28
T31725	1772-1775	NNP	denotes	mAb
T31726	1775-1776	,	denotes	,
T31727	1777-1779	CD	denotes	50
T31728	1780-1784	NNP	denotes	U/ml
T31729	1785-1789	NNP	denotes	IL-2
T31730	1789-1790	,	denotes	,
T31731	1791-1792	CD	denotes	±
T31732	1793-1795	CD	denotes	10
T31733	1796-1798	NN	denotes	nM
T31734	1799-1807	JJ	denotes	retinoic
T31735	1808-1812	NN	denotes	acid
T31736	1813-1814	-LRB-	denotes	(
T31737	1814-1816	NNP	denotes	RA
T31738	1816-1817	-RRB-	denotes	)
T31739	1817-1818	,	denotes	,
T31740	1819-1822	CC	denotes	and
T31741	1823-1833	VBG	denotes	increasing
T31742	1834-1848	NNS	denotes	concentrations
T31743	1849-1851	IN	denotes	of
T31744	1852-1857	NNP	denotes	TGF-β
T31745	1857-1858	.	denotes	.
T31746	1859-1864	IN	denotes	After
T31747	1865-1866	CD	denotes	3
T31748	1867-1868	LS	denotes	d
T31749	1869-1871	IN	denotes	in
T31750	1872-1879	NN	denotes	culture
T31751	1879-1880	,	denotes	,
T31752	1881-1884	DT	denotes	the
T31753	1885-1890	NNS	denotes	cells
T31754	1891-1895	VBD	denotes	were
T31755	1896-1908	VBN	denotes	restimulated
T31756	1909-1913	IN	denotes	with
T31757	1914-1917	NNP	denotes	PMA
T31758	1918-1919	CD	denotes	+
T31759	1920-1929	NN	denotes	ionomycin
T31760	1929-1930	,	denotes	,
T31761	1931-1934	CC	denotes	and
T31762	1935-1939	RB	denotes	then
T31763	1940-1948	VBD	denotes	analyzed
T31764	1949-1952	IN	denotes	for
T31765	1953-1966	JJ	denotes	intracellular
T31766	1967-1972	NNP	denotes	Foxp3
T31767	1973-1976	CC	denotes	and
T31768	1977-1982	NNP	denotes	IFN-γ
T31769	1983-1993	NN	denotes	expression
T31770	1993-1994	.	denotes	.
T31771	1995-1998	CD	denotes	One
T31772	1999-2001	IN	denotes	of
T31773	2002-2006	CD	denotes	five
T31774	2007-2018	NNS	denotes	experiments
T31775	2019-2021	VBZ	denotes	is
T31776	2022-2027	VBN	denotes	shown
T31777	2027-2028	.	denotes	.
T31778	2029-2030	-LRB-	denotes	(
T31779	2030-2031	NNP	denotes	B
T31780	2031-2032	-RRB-	denotes	)
T31781	2033-2038	NNP	denotes	Naive
T31782	2039-2042	NNP	denotes	CD4
T31783	2042-2043	VBD	denotes	+
T31784	2044-2045	NNP	denotes	T
T31785	2046-2051	NNS	denotes	cells
T31786	2052-2056	IN	denotes	from
T31787	2057-2061	NNP	denotes	Cbfb
T31788	2062-2069	NNP	denotes	CD4-cre
T31789	2070-2072	CC	denotes	or
T31790	2073-2080	VB	denotes	control
T31791	2081-2085	NNS	denotes	mice
T31792	2086-2087	-LRB-	denotes	(
T31793	2087-2096	VBG	denotes	harboring
T31794	2097-2098	DT	denotes	a
T31795	2099-2113	JJ	denotes	Foxp3-IRES-GFP
T31796	2114-2120	NN	denotes	allele
T31797	2120-2121	-RRB-	denotes	)
T31798	2122-2126	VBD	denotes	were
T31799	2127-2137	RB	denotes	adoptively
T31800	2138-2149	VBN	denotes	transferred
T31801	2150-2154	IN	denotes	into
T31802	2155-2168	JJ	denotes	Rag-deficient
T31803	2169-2173	NNS	denotes	mice
T31804	2174-2175	-LRB-	denotes	(
T31805	2175-2176	CD	denotes	5
T31806	2177-2178	CD	denotes	×
T31807	2179-2182	CD	denotes	106
T31808	2183-2188	NNS	denotes	cells
T31809	2189-2192	IN	denotes	per
T31810	2193-2201	NN	denotes	transfer
T31811	2201-2202	-RRB-	denotes	)
T31812	2202-2203	.	denotes	.
T31813	2204-2205	CD	denotes	6
T31814	2206-2208	NN	denotes	wk
T31815	2209-2214	RB	denotes	later
T31816	2214-2215	,	denotes	,
T31817	2216-2220	NNP	denotes	TCRβ
T31818	2220-2221	NNP	denotes	+
T31819	2221-2224	NNP	denotes	CD4
T31820	2224-2225	VBD	denotes	+
T31821	2226-2231	NNS	denotes	cells
T31822	2232-2236	IN	denotes	from
T31823	2237-2240	DT	denotes	the
T31824	2241-2247	NN	denotes	spleen
T31825	2247-2248	,	denotes	,
T31826	2249-2259	JJ	denotes	mesenteric
T31827	2260-2265	NN	denotes	lymph
T31828	2266-2270	NN	denotes	node
T31829	2271-2272	-LRB-	denotes	(
T31830	2272-2275	NNP	denotes	MLN
T31831	2275-2276	-RRB-	denotes	)
T31832	2276-2277	,	denotes	,
T31833	2278-2281	CC	denotes	and
T31834	2282-2288	NN	denotes	lamina
T31835	2289-2296	NN	denotes	propria
T31836	2297-2299	IN	denotes	of
T31837	2300-2303	DT	denotes	the
T31838	2304-2309	JJ	denotes	small
T31839	2310-2319	JJ	denotes	intestine
T31840	2320-2321	-LRB-	denotes	(
T31841	2321-2323	NNP	denotes	LP
T31842	2323-2324	-RRB-	denotes	)
T31843	2325-2329	VBD	denotes	were
T31844	2330-2338	VBN	denotes	analyzed
T31845	2339-2342	IN	denotes	for
T31846	2343-2352	JJ	denotes	Foxp3-GFP
T31847	2353-2363	NN	denotes	expression
T31848	2363-2364	.	denotes	.
T31849	2365-2372	NNS	denotes	Results
T31850	2373-2377	IN	denotes	from
T31851	2378-2381	CD	denotes	one
T31852	2382-2384	IN	denotes	of
T31853	2385-2389	CD	denotes	four
T31854	2390-2397	NNP	denotes	CbfbF/F
T31855	2398-2405	NNP	denotes	CD4-cre
T31856	2406-2409	CC	denotes	and
T31857	2410-2417	NN	denotes	control
T31858	2418-2423	NNP	denotes	CbfbF
T31859	2423-2424	NNP	denotes	/
T31860	2424-2425	VBD	denotes	+
T31861	2426-2433	JJ	denotes	CD4-cre
T31862	2434-2438	NNS	denotes	mice
T31863	2439-2443	IN	denotes	with
T31864	2444-2448	JJ	denotes	same
T31865	2449-2457	NNS	denotes	findings
T31866	2458-2461	VBP	denotes	are
T31867	2462-2467	VBN	denotes	shown
T31868	2467-2468	.	denotes	.
T31869	2469-2472	DT	denotes	The
T31870	2473-2477	NNS	denotes	data
T31871	2478-2482	IN	denotes	from
T31872	2483-2487	CD	denotes	four
T31873	2488-2492	NNS	denotes	sets
T31874	2493-2495	IN	denotes	of
T31875	2496-2500	NNS	denotes	mice
T31876	2501-2503	VBZ	denotes	is
T31877	2504-2509	VBN	denotes	shown
T31878	2510-2512	IN	denotes	in
T31879	2513-2515	NNP	denotes	C.
T31880	2516-2527	NNP	denotes	Statistical
T31881	2528-2536	NN	denotes	analysis
T31882	2537-2540	VBD	denotes	was
T31883	2541-2550	VBN	denotes	performed
T31884	2551-2555	IN	denotes	with
T31885	2556-2568	NNP	denotes	Mann-Whitney
T31886	2569-2570	NNP	denotes	U
T31887	2571-2575	NN	denotes	test
T31888	2575-2576	.	denotes	.
T31889	2577-2578	SYM	denotes	*
T31890	2578-2579	,	denotes	,
T31891	2580-2581	NNP	denotes	P
T31892	2582-2583	VBD	denotes	<
T31893	2584-2588	CD	denotes	0.05
T31894	2589-2596	IN	denotes	between
T31895	2597-2603	NNS	denotes	groups
T31896	2603-2604	.	denotes	.
R7577	T9575	T9572	pobj	domain,of
R7578	T9576	T9577	aux	to,target
R7579	T9577	T9569	xcomp	target,increases
R7580	T9578	T9579	compound	DNA,sequences
R7581	T9579	T9577	dobj	sequences,target
R7582	T9580	T9567	punct	.,stabilizes
R7583	T9581	T9582	aux	To,target
R7584	T9582	T9597	advcl	target,used
R7585	T9583	T9585	det	all,proteins
R7586	T9584	T9585	compound	Runx,proteins
R7587	T9585	T9582	dobj	proteins,target
R7588	T9586	T9589	nsubjpass	that,involved
R7589	T9587	T9589	aux	might,involved
R7590	T9588	T9589	auxpass	be,involved
R7591	T9589	T9585	relcl	involved,proteins
R7592	T9590	T9589	prep	in,involved
R7593	T9591	T9592	det	the,induction
R7594	T9592	T9590	pobj	induction,in
R7595	T9593	T9592	prep	of,induction
R7596	T9594	T9593	pobj	Foxp3,of
R7597	T9595	T9597	punct	",",used
R7598	T9596	T9597	nsubj	we,used
R7599	T9597	T9597	ROOT	used,used
R7600	T9598	T9597	dobj	mice,used
R7601	T9599	T9605	prep	in,inactivated
R7602	T9600	T9599	pobj	which,in
R7603	T9601	T9603	compound	loxP-flanked,alleles
R7604	T9602	T9603	compound	Cbfb,alleles
R7605	T9603	T9605	nsubjpass	alleles,inactivated
R7606	T9604	T9605	auxpass	were,inactivated
R7607	T9605	T9598	relcl	inactivated,mice
R7608	T9606	T9605	prep	in,inactivated
R7609	T9607	T9608	compound	T,cells
R7610	T9608	T9606	pobj	cells,in
R7611	T9609	T9605	prep	through,inactivated
R7612	T9610	T9609	pobj	expression,through
R7613	T9611	T9610	prep	of,expression
R7614	T9612	T9614	det	a,transgene
R7615	T9613	T9614	amod	CD4-cre,transgene
R7616	T9614	T9611	pobj	transgene,of
R7617	T9615	T9597	punct	.,used
R7618	T9616	T9617	compound	Retinoic,acid
R7619	T9617	T9633	nmod	acid,al.
R7620	T9618	T9617	cc	and,acid
R7621	T9619	T9620	amod	TGF-β,synergize
R7622	T9620	T9617	conj	synergize,acid
R7623	T9621	T9620	prep	in,synergize
R7624	T9622	T9623	det	the,induction
R7625	T9623	T9621	pobj	induction,in
R7626	T9624	T9623	prep	of,induction
R7627	T9625	T9624	pobj	Foxp3,of
R7628	T9626	T9623	prep	in,induction
R7629	T9627	T9629	amod	naive,cells
R7630	T9628	T9629	compound	T,cells
R7631	T9629	T9626	pobj	cells,in
R7632	T9630	T9620	punct	(,synergize
R7633	T9631	T9633	nmod	Kang,al.
R7634	T9632	T9633	nmod	et,al.
R7635	T9633	T9633	ROOT	al.,al.
R7636	T9634	T9633	punct	",",al.
R7637	T9635	T9633	npadvmod	2007,al.
R7638	T9636	T9633	punct	),al.
R7639	T9637	T9633	punct	.,al.
R7640	T9638	T9639	aux	To,investigate
R7641	T9639	T9639	ROOT	investigate,investigate
R7642	T9640	T9645	mark	whether,is
R7643	T9641	T9642	amod	Runx-mediated,induction
R7644	T9642	T9645	nsubj	induction,is
R7645	T9643	T9642	prep	of,induction
R7646	T9644	T9643	pobj	Foxp3,of
R7647	T9645	T9639	ccomp	is,investigate
R7648	T9646	T9645	acomp	dependent,is
R7649	T9647	T9646	prep	on,dependent
R7650	T9648	T9649	det	the,expression
R7651	T9649	T9647	pobj	expression,on
R7652	T9650	T9649	prep	of,expression
R7653	T9651	T9650	pobj	CBFβ,of
R7654	T9652	T9646	punct	",",dependent
R7655	T9653	T9659	amod	naive,cells
R7656	T9654	T9657	intj	CD4,−
R7657	T9655	T9657	npadvmod	+,−
R7658	T9656	T9657	nsubj	CD8,−
R7659	T9657	T9659	amod	−,cells
R7660	T9658	T9659	compound	T,cells
R7661	T9659	T9671	nsubjpass	cells,stimulated
R7662	T9660	T9659	prep	from,cells
R7663	T9661	T9662	compound	CbfbF/F,CD4-cre
R7664	T9662	T9660	pobj	CD4-cre,from
R7665	T9663	T9662	cc	and,CD4-cre
R7666	T9664	T9666	compound	control,/
R7667	T9665	T9666	compound	CbfbF,/
R7668	T9666	T9662	conj	/,CD4-cre
R7669	T9667	T9669	amod	+,mice
R7670	T9668	T9669	amod	CD4-cre,mice
R7671	T9669	T9659	conj	mice,cells
R7672	T9670	T9671	auxpass	were,stimulated
R7673	T9671	T9645	conj	stimulated,is
R7674	T9672	T9671	prep	with,stimulated
R7675	T9673	T9676	amod	anti-CD3,mAbs
R7676	T9674	T9676	nmod	/,mAbs
R7677	T9675	T9674	nummod	28,/
R7678	T9676	T9672	pobj	mAbs,with
R7679	T9677	T9676	punct	",",mAbs
R7680	T9678	T9679	amod	retinoic,acid
R7681	T9679	T9676	conj	acid,mAbs
R7682	T9680	T9679	punct	",",acid
R7683	T9681	T9679	cc	and,acid
R7684	T9682	T9683	amod	increasing,concentrations
R7685	T9683	T9679	conj	concentrations,acid
R7686	T9684	T9683	prep	of,concentrations
R7687	T9685	T9684	pobj	TGF-β,of
R7688	T9686	T9671	punct	.,stimulated
R7689	T9687	T9696	prep	After,restimulated
R7690	T9688	T9689	nummod	3,d
R7691	T9689	T9687	pobj	d,After
R7692	T9690	T9689	prep	in,d
R7693	T9691	T9690	pobj	culture,in
R7694	T9692	T9696	punct	",",restimulated
R7695	T9693	T9694	det	the,cells
R7696	T9694	T9696	nsubjpass	cells,restimulated
R7697	T9695	T9696	auxpass	were,restimulated
R7698	T9696	T9696	ROOT	restimulated,restimulated
R7699	T9697	T9696	prep	with,restimulated
R7700	T9698	T9697	pobj	PMA,with
R7701	T9699	T9698	cc	and,PMA
R7702	T9700	T9698	conj	ionomycin,PMA
R7703	T9701	T9696	cc	and,restimulated
R7704	T9702	T9696	conj	analyzed,restimulated
R7705	T9703	T9702	prep	for,analyzed
R7706	T9704	T9705	compound	intracellular,Foxp3
R7707	T9705	T9703	pobj	Foxp3,for
R7708	T9706	T9705	cc	and,Foxp3
R7709	T9707	T9708	compound	IFN-γ,expression
R7710	T9708	T9705	conj	expression,Foxp3
R7711	T9709	T9696	punct	.,restimulated
R7712	T9710	T9712	amod	TGF-β,Foxp3
R7713	T9711	T9712	amod	induced,Foxp3
R7714	T9712	T9716	nsubj	Foxp3,+
R7715	T9713	T9712	prep	in,Foxp3
R7716	T9714	T9715	compound	CbfbF,/
R7717	T9715	T9713	pobj	/,in
R7718	T9716	T9716	ROOT	+,+
R7719	T9717	T9718	amod	CD4-cre,cells
R7720	T9718	T9716	dobj	cells,+
R7721	T9719	T9716	prep	in,+
R7722	T9720	T9721	det	a,dose
R7723	T9721	T9719	pobj	dose,in
R7724	T9722	T9723	amod	dependent,manner
R7725	T9723	T9716	conj	manner,+
R7726	T9724	T9723	punct	",",manner
R7727	T9725	T9729	cc	and,reduced
R7728	T9726	T9729	nsubjpass	this,reduced
R7729	T9727	T9729	auxpass	was,reduced
R7730	T9728	T9729	advmod	significantly,reduced
R7731	T9729	T9716	conj	reduced,+
R7732	T9730	T9729	prep	in,reduced
R7733	T9731	T9732	compound	CbfbF/F,CD4-cre
R7734	T9732	T9733	compound	CD4-cre,cells
R7735	T9733	T9730	pobj	cells,in
R7736	T9734	T9729	punct	.,reduced
R7737	T9735	T9760	intj	Retinoic,+
R7738	T9736	T9739	nmod	acid,expression
R7739	T9737	T9739	amod	enhanced,expression
R7740	T9738	T9739	amod	Foxp3,expression
R7741	T9739	T9735	appos	expression,Retinoic
R7742	T9740	T9741	advmod	even,in
R7743	T9741	T9739	prep	in,expression
R7744	T9742	T9743	nummod	20,pg/ml
R7745	T9743	T9741	pobj	pg/ml,in
R7746	T9744	T9743	prep	of,pg/ml
R7747	T9745	T9744	pobj	TGF-β,of
R7748	T9746	T9743	cc	and,pg/ml
R7749	T9747	T9749	amod	more,95
R7750	T9748	T9749	quantmod	than,95
R7751	T9749	T9750	nummod	95,%
R7752	T9750	T9760	nsubj	%,+
R7753	T9751	T9750	prep	of,%
R7754	T9752	T9756	det	the,cells
R7755	T9753	T9756	compound	CD4,cells
R7756	T9754	T9756	nummod	+,cells
R7757	T9755	T9756	compound	T,cells
R7758	T9756	T9751	pobj	cells,of
R7759	T9757	T9750	prep	from,%
R7760	T9758	T9759	compound	CbfbF,/
R7761	T9759	T9757	pobj	/,from
R7762	T9760	T9760	ROOT	+,+
R7763	T9761	T9762	amod	CD4-cre,mice
R7764	T9762	T9763	nsubj	mice,became
R7765	T9763	T9763	ROOT	became,became
R7766	T9764	T9765	compound	Foxp3,+
R7767	T9765	T9763	attr	+,became
R7768	T9766	T9765	prep	in,+
R7769	T9767	T9766	pobj	100,in
R7770	T9768	T9767	cc	and,100
R7771	T9769	T9767	conj	500,100
R7772	T9770	T9772	amod	pg/ml,doses
R7773	T9771	T9772	amod	TGF-β,doses
R7774	T9772	T9767	conj	doses,100
R7775	T9773	T9763	punct	.,became
R7776	T9774	T9775	det	The,induction
R7777	T9775	T9778	nsubj	induction,was
R7778	T9776	T9775	prep	of,induction
R7779	T9777	T9776	pobj	Foxp3,of
R7780	T9778	T9778	ROOT	was,was
R7781	T9779	T9778	advmod	again,was
R7782	T9780	T9781	advmod	significantly,lower
R7783	T9781	T9778	acomp	lower,was
R7784	T9782	T9778	prep	in,was
R7785	T9783	T9784	compound	CbfbF/F,CD4-cre
R7786	T9784	T9785	compound	CD4-cre,CD4
R7787	T9785	T9782	pobj	CD4,in
R7788	T9786	T9805	csubj	+,affects
R7789	T9787	T9788	compound	T,cells
R7790	T9788	T9786	dobj	cells,+
R7791	T9789	T9790	advmod	even,in
R7792	T9790	T9786	prep	in,+
R7793	T9791	T9792	det	the,presence
R7794	T9792	T9790	pobj	presence,in
R7795	T9793	T9792	prep	of,presence
R7796	T9794	T9795	amod	retinoic,acid
R7797	T9795	T9793	pobj	acid,of
R7798	T9796	T9786	punct	",",+
R7799	T9797	T9805	csubj	demonstrating,affects
R7800	T9798	T9802	mark	that,binding
R7801	T9799	T9802	nsubj	deficiency,binding
R7802	T9800	T9799	prep	in,deficiency
R7803	T9801	T9800	pobj	Runx,in
R7804	T9802	T9797	ccomp	binding,demonstrating
R7805	T9803	T9802	prep	to,binding
R7806	T9804	T9803	pobj	DNA,to
R7807	T9805	T9778	ccomp	affects,was
R7808	T9806	T9808	det	the,induction
R7809	T9807	T9808	amod	TGF-β,induction
R7810	T9808	T9805	dobj	induction,affects
R7811	T9809	T9808	prep	of,induction
R7812	T9810	T9809	pobj	Foxp3,of
R7813	T9811	T9808	prep	in,induction
R7814	T9812	T9814	compound	T,cells
R7815	T9813	T9814	compound	reg,cells
R7816	T9814	T9811	pobj	cells,in
R7817	T9815	T9818	punct	(,A
R7818	T9816	T9818	punct	Fig.,A
R7819	T9817	T9816	nummod	5,Fig.
R7820	T9818	T9808	appos	A,induction
R7821	T9819	T9818	punct	),A
R7822	T9820	T9778	punct	.,was
R7823	T9821	T9822	expl	There,was
R7824	T9822	T9822	ROOT	was,was
R7825	T9823	T9824	det	no,difference
R7826	T9824	T9822	attr	difference,was
R7827	T9825	T9824	prep	in,difference
R7828	T9826	T9827	det	the,induction
R7829	T9827	T9825	pobj	induction,in
R7830	T9828	T9827	prep	of,induction
R7831	T9829	T9828	pobj	Foxp3,of
R7832	T9830	T9836	advmod	when,neutralized
R7833	T9831	T9832	amod	endogenous,IL-4
R7834	T9832	T9836	nsubjpass	IL-4,neutralized
R7835	T9833	T9832	cc	and,IL-4
R7836	T9834	T9832	conj	IFN-γ,IL-4
R7837	T9835	T9836	auxpass	were,neutralized
R7838	T9836	T9824	relcl	neutralized,difference
R7839	T9837	T9838	punct	(,Fig
R7840	T9838	T9836	dobj	Fig,neutralized
R7841	T9839	T9822	punct	.,was
R7842	T9840	T9840	ROOT	S6,S6
R7843	T9841	T9840	punct	),S6
R7844	T9842	T9840	punct	.,S6
R7845	T9843	T9844	det	The,importance
R7846	T9844	T9844	ROOT	importance,importance
R7847	T9845	T9844	prep	of,importance
R7848	T9846	T9848	compound	RUNX,factors
R7849	T9847	T9848	compound	transcription,factors
R7850	T9848	T9845	pobj	factors,of
R7851	T9849	T9844	prep	for,importance
R7852	T9850	T9865	det	the,examined
R7853	T9851	T9865	prep	in,examined
R7854	T9852	T9853	compound	vivo,conversion
R7855	T9853	T9851	pobj	conversion,in
R7856	T9854	T9853	prep	of,conversion
R7857	T9855	T9859	amod	naive,cells
R7858	T9856	T9859	compound	CD4,cells
R7859	T9857	T9859	nummod	+,cells
R7860	T9858	T9859	compound	T,cells
R7861	T9859	T9854	pobj	cells,of
R7862	T9860	T9853	prep	into,conversion
R7863	T9861	T9863	compound	iT,cells
R7864	T9862	T9863	compound	reg,cells
R7865	T9863	T9860	pobj	cells,into
R7866	T9864	T9865	auxpass	was,examined
R7867	T9865	T9849	pobj	examined,for
R7868	T9866	T9844	punct	.,importance
R7869	T9867	T9868	compound	Control,CbfbF/F
R7870	T9868	T9874	nmod	CbfbF/F,cells
R7871	T9869	T9868	cc	or,CbfbF/F
R7872	T9870	T9871	compound	CbfbF/F,CD4-cre
R7873	T9871	T9868	conj	CD4-cre,CbfbF/F
R7874	T9872	T9874	amod	naive,cells
R7875	T9873	T9874	compound	T,cells
R7876	T9874	T9882	nsubjpass	cells,transferred
R7877	T9875	T9874	punct	",",cells
R7878	T9876	T9874	acl	harboring,cells
R7879	T9877	T9879	det	a,allele
R7880	T9878	T9879	amod	Foxp3-IRES-GFP,allele
R7881	T9879	T9876	dobj	allele,harboring
R7882	T9880	T9882	auxpass	were,transferred
R7883	T9881	T9882	advmod	adoptively,transferred
R7884	T9882	T9882	ROOT	transferred,transferred
R7885	T9883	T9882	prep	into,transferred
R7886	T9884	T9885	compound	Rag2,−
R7887	T9885	T9883	pobj	−,into
R7888	T9886	T9882	advcl	/,transferred
R7889	T9887	T9888	nummod	−,mice
R7890	T9888	T9886	dobj	mice,/
R7891	T9889	T9882	punct	.,transferred
R7892	T9890	T9891	nummod	6,wk
R7893	T9891	T9892	npadvmod	wk,later
R7894	T9892	T9913	advmod	later,analyzed
R7895	T9893	T9913	punct	",",analyzed
R7896	T9894	T9897	compound	CD4,cells
R7897	T9895	T9897	compound	+,cells
R7898	T9896	T9897	compound	T,cells
R7899	T9897	T9913	nsubjpass	cells,analyzed
R7900	T9898	T9897	prep	in,cells
R7901	T9899	T9898	pobj	spleen,in
R7902	T9900	T9897	punct	",",cells
R7903	T9901	T9903	amod	mesenteric,node
R7904	T9902	T9903	amod	lymph,node
R7905	T9903	T9897	appos	node,cells
R7906	T9904	T9903	punct	",",node
R7907	T9905	T9903	cc	and,node
R7908	T9906	T9907	compound	lamina,propria
R7909	T9907	T9903	conj	propria,node
R7910	T9908	T9907	prep	of,propria
R7911	T9909	T9911	det	the,intestine
R7912	T9910	T9911	amod	small,intestine
R7913	T9911	T9908	pobj	intestine,of
R7914	T9912	T9913	auxpass	were,analyzed
R7915	T9913	T9913	ROOT	analyzed,analyzed
R7916	T9914	T9913	prep	for,analyzed
R7917	T9915	T9916	amod	Foxp3-GFP,expression
R7918	T9916	T9914	pobj	expression,for
R7919	T9917	T9918	punct	(,Fig.
R7920	T9918	T9920	nmod	Fig.,B
R7921	T9919	T9920	nummod	5,B
R7922	T9920	T9916	appos	B,expression
R7923	T9921	T9913	punct	),analyzed
R7924	T9922	T9913	punct	.,analyzed
R7925	T9923	T9924	expl	There,was
R7926	T9924	T9924	ROOT	was,was
R7927	T9925	T9928	det	a,percentage
R7928	T9926	T9927	advmod	consistently,lower
R7929	T9927	T9928	amod	lower,percentage
R7930	T9928	T9924	attr	percentage,was
R7931	T9929	T9928	prep	of,percentage
R7932	T9930	T9933	nummod	CD4,cells
R7933	T9931	T9933	nummod	+,cells
R7934	T9932	T9933	compound	T,cells
R7935	T9933	T9929	pobj	cells,of
R7936	T9934	T9936	nsubj	that,developed
R7937	T9935	T9936	aux	had,developed
R7938	T9936	T9933	relcl	developed,cells
R7939	T9937	T9938	amod	Foxp3,expression
R7940	T9938	T9936	dobj	expression,developed
R7941	T9939	T9936	prep	in,developed
R7942	T9940	T9943	det	the,node
R7943	T9941	T9943	amod	mesenteric,node
R7944	T9942	T9943	compound	lymph,node
R7945	T9943	T9939	pobj	node,in
R7946	T9944	T9943	cc	and,node
R7947	T9945	T9946	compound	lamina,propria
R7948	T9946	T9943	conj	propria,node
R7949	T9947	T9946	prep	of,propria
R7950	T9948	T9947	pobj	mice,of
R7951	T9949	T9948	acl	transferred,mice
R7952	T9950	T9949	prep	with,transferred
R7953	T9951	T9952	compound	CbfbF/F,CD4-cre
R7954	T9952	T9953	compound	CD4-cre,cells
R7955	T9953	T9950	pobj	cells,with
R7956	T9954	T9949	prep	compared,transferred
R7957	T9955	T9954	prep	with,compared
R7958	T9956	T9957	compound	control,cells
R7959	T9957	T9955	pobj	cells,with
R7960	T9958	T9962	punct	(,B
R7961	T9959	T9962	amod	Fig.,B
R7962	T9960	T9959	nummod	5,Fig.
R7963	T9961	T9959	punct	",",Fig.
R7964	T9962	T9957	appos	B,cells
R7965	T9963	T9962	cc	and,B
R7966	T9964	T9962	conj	C,B
R7967	T9965	T9962	punct	),B
R7968	T9966	T9924	punct	.,was
R7969	T9967	T9968	det	These,data
R7970	T9968	T9969	nsubj	data,affirm
R7971	T9969	T9969	ROOT	affirm,affirm
R7972	T9970	T9971	det	the,significance
R7973	T9971	T9969	dobj	significance,affirm
R7974	T9972	T9971	prep	of,significance
R7975	T9973	T9974	compound	RUNX,proteins
R7976	T9974	T9972	pobj	proteins,of
R7977	T9975	T9971	prep	for,significance
R7978	T9976	T9979	det	the,generation
R7979	T9977	T9979	nmod	in,generation
R7980	T9978	T9979	amod	vivo,generation
R7981	T9979	T9975	pobj	generation,for
R7982	T9980	T9979	prep	of,generation
R7983	T9981	T9984	compound	CD4,+
R7984	T9982	T9984	compound	+,+
R7985	T9983	T9984	nsubj	Foxp3,+
R7986	T9984	T9969	conj	+,affirm
R7987	T9985	T9986	compound	T,cells
R7988	T9986	T9984	dobj	cells,+
R7989	T9987	T9984	punct	.,+
R24314	T31677	T31678	amod	Diminished,capacity
R24315	T31678	T31678	ROOT	capacity,capacity
R24316	T31679	T31678	prep	of,capacity
R24317	T31680	T31682	amod	Cbfb-deficient,mice
R24318	T31681	T31682	amod	CD4-cre,mice
R24319	T31682	T31679	pobj	mice,of
R24320	T31683	T31684	compound	T,cells
R24321	T31684	T31678	conj	cells,capacity
R24322	T31685	T31678	prep	in,capacity
R24323	T31686	T31687	det	the,generation
R24324	T31687	T31685	pobj	generation,in
R24325	T31688	T31687	prep	of,generation
R24326	T31689	T31692	nmod	Foxp3,+
R24327	T31690	T31692	amod	+,+
R24328	T31691	T31692	compound	CD4,+
R24329	T31692	T31692	ROOT	+,+
R24330	T31693	T31694	compound	T,cells
R24331	T31694	T31692	dobj	cells,+
R24332	T31695	T31692	punct	.,+
R24333	T31696	T31697	punct	(,A
R24334	T31697	T31718	nsubjpass	A,activated
R24335	T31698	T31697	punct	),A
R24336	T31699	T31701	amod	FACS-purified,CD4
R24337	T31700	T31701	amod	naive,CD4
R24338	T31701	T31704	dep	CD4,−
R24339	T31702	T31704	npadvmod	+,−
R24340	T31703	T31704	nsubj	CD8,−
R24341	T31704	T31718	advcl	−,activated
R24342	T31705	T31706	compound	T,cells
R24343	T31706	T31704	dobj	cells,−
R24344	T31707	T31704	prep	from,−
R24345	T31708	T31709	compound	CbfbF/F,CD4-cre
R24346	T31709	T31707	pobj	CD4-cre,from
R24347	T31710	T31709	cc	and,CD4-cre
R24348	T31711	T31713	compound	control,/
R24349	T31712	T31713	compound	CbfbF,/
R24350	T31713	T31709	conj	/,CD4-cre
R24351	T31714	T31716	amod	+,mice
R24352	T31715	T31716	amod	CD4-cre,mice
R24353	T31716	T31718	nsubjpass	mice,activated
R24354	T31717	T31718	auxpass	were,activated
R24355	T31718	T31718	ROOT	activated,activated
R24356	T31719	T31718	prep	in,activated
R24357	T31720	T31719	pobj	vitro,in
R24358	T31721	T31720	prep	with,vitro
R24359	T31722	T31725	amod	anti-CD3,mAb
R24360	T31723	T31725	nmod	/,mAb
R24361	T31724	T31723	nummod	28,/
R24362	T31725	T31721	pobj	mAb,with
R24363	T31726	T31725	punct	",",mAb
R24364	T31727	T31729	nummod	50,IL-2
R24365	T31728	T31729	compound	U/ml,IL-2
R24366	T31729	T31725	appos	IL-2,mAb
R24367	T31730	T31725	punct	",",mAb
R24368	T31731	T31735	nummod	±,acid
R24369	T31732	T31733	nummod	10,nM
R24370	T31733	T31735	nmod	nM,acid
R24371	T31734	T31735	amod	retinoic,acid
R24372	T31735	T31725	appos	acid,mAb
R24373	T31736	T31737	punct	(,RA
R24374	T31737	T31735	appos	RA,acid
R24375	T31738	T31737	punct	),RA
R24376	T31739	T31735	punct	",",acid
R24377	T31740	T31735	cc	and,acid
R24378	T31741	T31742	amod	increasing,concentrations
R24379	T31742	T31735	conj	concentrations,acid
R24380	T31743	T31742	prep	of,concentrations
R24381	T31744	T31743	pobj	TGF-β,of
R24382	T31745	T31718	punct	.,activated
R24383	T31746	T31755	mark	After,restimulated
R24384	T31747	T31748	nummod	3,d
R24385	T31748	T31755	advcl	d,restimulated
R24386	T31749	T31748	prep	in,d
R24387	T31750	T31749	pobj	culture,in
R24388	T31751	T31755	punct	",",restimulated
R24389	T31752	T31753	det	the,cells
R24390	T31753	T31755	nsubjpass	cells,restimulated
R24391	T31754	T31755	auxpass	were,restimulated
R24392	T31755	T31755	ROOT	restimulated,restimulated
R24393	T31756	T31755	prep	with,restimulated
R24394	T31757	T31759	nsubj	PMA,ionomycin
R24395	T31758	T31759	nummod	+,ionomycin
R24396	T31759	T31756	pobj	ionomycin,with
R24397	T31760	T31759	punct	",",ionomycin
R24398	T31761	T31755	cc	and,restimulated
R24399	T31762	T31763	advmod	then,analyzed
R24400	T31763	T31755	conj	analyzed,restimulated
R24401	T31764	T31763	prep	for,analyzed
R24402	T31765	T31766	compound	intracellular,Foxp3
R24403	T31766	T31764	pobj	Foxp3,for
R24404	T31767	T31766	cc	and,Foxp3
R24405	T31768	T31769	compound	IFN-γ,expression
R24406	T31769	T31766	conj	expression,Foxp3
R24407	T31770	T31755	punct	.,restimulated
R24408	T31771	T31776	nsubjpass	One,shown
R24409	T31772	T31771	prep	of,One
R24410	T31773	T31774	nummod	five,experiments
R24411	T31774	T31772	pobj	experiments,of
R24412	T31775	T31776	auxpass	is,shown
R24413	T31776	T31776	ROOT	shown,shown
R24414	T31777	T31776	punct	.,shown
R24415	T31778	T31790	punct	(,control
R24416	T31779	T31782	compound	B,CD4
R24417	T31780	T31781	punct	),Naive
R24418	T31781	T31782	compound	Naive,CD4
R24419	T31782	T31790	nsubj	CD4,control
R24420	T31783	T31790	dep	+,control
R24421	T31784	T31785	compound	T,cells
R24422	T31785	T31783	dobj	cells,+
R24423	T31786	T31783	prep	from,+
R24424	T31787	T31788	compound	Cbfb,CD4-cre
R24425	T31788	T31786	pobj	CD4-cre,from
R24426	T31789	T31788	cc	or,CD4-cre
R24427	T31790	T31790	ROOT	control,control
R24428	T31791	T31790	dobj	mice,control
R24429	T31792	T31791	punct	(,mice
R24430	T31793	T31791	acl	harboring,mice
R24431	T31794	T31796	det	a,allele
R24432	T31795	T31796	amod	Foxp3-IRES-GFP,allele
R24433	T31796	T31793	dobj	allele,harboring
R24434	T31797	T31791	punct	),mice
R24435	T31798	T31800	auxpass	were,transferred
R24436	T31799	T31800	advmod	adoptively,transferred
R24437	T31800	T31790	ccomp	transferred,control
R24438	T31801	T31800	prep	into,transferred
R24439	T31802	T31803	amod	Rag-deficient,mice
R24440	T31803	T31801	pobj	mice,into
R24441	T31804	T31803	punct	(,mice
R24442	T31805	T31808	nummod	5,cells
R24443	T31806	T31808	nummod	×,cells
R24444	T31807	T31808	nummod	106,cells
R24445	T31808	T31800	npadvmod	cells,transferred
R24446	T31809	T31808	prep	per,cells
R24447	T31810	T31809	pobj	transfer,per
R24448	T31811	T31790	punct	),control
R24449	T31812	T31790	punct	.,control
R24450	T31813	T31814	nummod	6,wk
R24451	T31814	T31815	npadvmod	wk,later
R24452	T31815	T31820	advmod	later,+
R24453	T31816	T31820	punct	",",+
R24454	T31817	T31819	compound	TCRβ,CD4
R24455	T31818	T31819	compound	+,CD4
R24456	T31819	T31820	nsubj	CD4,+
R24457	T31820	T31820	ROOT	+,+
R24458	T31821	T31820	dobj	cells,+
R24459	T31822	T31821	prep	from,cells
R24460	T31823	T31824	det	the,spleen
R24461	T31824	T31822	pobj	spleen,from
R24462	T31825	T31824	punct	",",spleen
R24463	T31826	T31828	amod	mesenteric,node
R24464	T31827	T31828	amod	lymph,node
R24465	T31828	T31844	nsubjpass	node,analyzed
R24466	T31829	T31830	punct	(,MLN
R24467	T31830	T31828	appos	MLN,node
R24468	T31831	T31830	punct	),MLN
R24469	T31832	T31828	punct	",",node
R24470	T31833	T31828	cc	and,node
R24471	T31834	T31835	compound	lamina,propria
R24472	T31835	T31828	conj	propria,node
R24473	T31836	T31835	prep	of,propria
R24474	T31837	T31839	det	the,intestine
R24475	T31838	T31839	amod	small,intestine
R24476	T31839	T31836	pobj	intestine,of
R24477	T31840	T31839	punct	(,intestine
R24478	T31841	T31839	appos	LP,intestine
R24479	T31842	T31839	punct	),intestine
R24480	T31843	T31844	auxpass	were,analyzed
R24481	T31844	T31820	conj	analyzed,+
R24482	T31845	T31844	prep	for,analyzed
R24483	T31846	T31847	amod	Foxp3-GFP,expression
R24484	T31847	T31845	pobj	expression,for
R24485	T31848	T31844	punct	.,analyzed
R24486	T31849	T31860	nsubj	Results,+
R24487	T31850	T31849	prep	from,Results
R24488	T31851	T31850	pobj	one,from
R24489	T31852	T31851	prep	of,one
R24490	T31853	T31855	nummod	four,CD4-cre
R24491	T31854	T31855	compound	CbfbF/F,CD4-cre
R24492	T31855	T31852	pobj	CD4-cre,of
R24493	T31856	T31855	cc	and,CD4-cre
R24494	T31857	T31859	compound	control,/
R24495	T31858	T31859	compound	CbfbF,/
R24496	T31859	T31855	conj	/,CD4-cre
R24497	T31860	T31860	ROOT	+,+
R24498	T31861	T31862	amod	CD4-cre,mice
R24499	T31862	T31860	dobj	mice,+
R24500	T31863	T31860	prep	with,+
R24501	T31864	T31865	amod	same,findings
R24502	T31865	T31863	pobj	findings,with
R24503	T31866	T31867	auxpass	are,shown
R24504	T31867	T31860	advcl	shown,+
R24505	T31868	T31860	punct	.,+
R24506	T31869	T31870	det	The,data
R24507	T31870	T31877	nsubjpass	data,shown
R24508	T31871	T31870	prep	from,data
R24509	T31872	T31873	nummod	four,sets
R24510	T31873	T31871	pobj	sets,from
R24511	T31874	T31873	prep	of,sets
R24512	T31875	T31874	pobj	mice,of
R24513	T31876	T31877	auxpass	is,shown
R24514	T31877	T31877	ROOT	shown,shown
R24515	T31878	T31877	prep	in,shown
R24516	T31879	T31880	compound	C.,Statistical
R24517	T31880	T31881	compound	Statistical,analysis
R24518	T31881	T31878	pobj	analysis,in
R24519	T31882	T31883	auxpass	was,performed
R24520	T31883	T31877	conj	performed,shown
R24521	T31884	T31883	prep	with,performed
R24522	T31885	T31887	compound	Mann-Whitney,test
R24523	T31886	T31887	compound	U,test
R24524	T31887	T31884	pobj	test,with
R24525	T31888	T31877	punct	.,shown
R24526	T31889	T31892	advcl	*,<
R24527	T31890	T31892	punct	",",<
R24528	T31891	T31892	nsubj	P,<
R24529	T31892	T31892	ROOT	<,<
R24530	T31893	T31892	dobj	0.05,<
R24531	T31894	T31892	prep	between,<
R24532	T31895	T31894	pobj	groups,between
R24533	T31896	T31892	punct	.,<
R7551	T9549	T9567	nsubj	Role,stabilizes
R7552	T9550	T9549	prep	of,Role
R7553	T9551	T9550	pobj	CBFβ,of
R7554	T9552	T9549	prep	in,Role
R7555	T9553	T9554	det	the,induction
R7556	T9554	T9552	pobj	induction,in
R7557	T9555	T9554	prep	of,induction
R7558	T9556	T9557	compound	Foxp3,CBFβ
R7559	T9557	T9555	pobj	CBFβ,of
R7560	T9558	T9557	punct	",",CBFβ
R7561	T9559	T9561	det	a,cofactor
R7562	T9560	T9561	amod	common,cofactor
R7563	T9561	T9557	appos	cofactor,CBFβ
R7564	T9562	T9561	prep	of,cofactor
R7565	T9563	T9565	det	all,proteins
R7566	T9564	T9565	compound	RUNX,proteins
R7567	T9565	T9562	pobj	proteins,of
R7568	T9566	T9557	punct	",",CBFβ
R7569	T9567	T9567	ROOT	stabilizes,stabilizes
R7570	T9568	T9567	cc	and,stabilizes
R7571	T9569	T9567	conj	increases,stabilizes
R7572	T9570	T9571	det	the,binding
R7573	T9571	T9569	dobj	binding,increases
R7574	T9572	T9571	prep	of,binding
R7575	T9573	T9575	det	the,domain
R7576	T9574	T9575	compound	runt,domain

UBERON-AE

Id	Subject	Object	Predicate	Lexical cue
T8925	3117-3138	http://purl.obolibrary.org/obo/UBERON_0002509	denotes	mesenteric lymph node
T8926	2911-2916	http://purl.obolibrary.org/obo/UBERON_0002391	denotes	lymph
T8927	3128-3133	http://purl.obolibrary.org/obo/UBERON_0002391	denotes	lymph
T8928	2911-2921	http://purl.obolibrary.org/obo/UBERON_0000029	denotes	lymph node
T8929	3128-3138	http://purl.obolibrary.org/obo/UBERON_0000029	denotes	lymph node
T8930	2927-2933	http://purl.obolibrary.org/obo/UBERON_0000957	denotes	lamina
T8931	3143-3149	http://purl.obolibrary.org/obo/UBERON_0000957	denotes	lamina
T8932	2927-2941	http://purl.obolibrary.org/obo/UBERON_0000030	denotes	lamina propria
T8933	3143-3157	http://purl.obolibrary.org/obo/UBERON_0000030	denotes	lamina propria
T8934	2949-2964	http://purl.obolibrary.org/obo/UBERON_0002108	denotes	small intestine
T8935	2955-2964	http://purl.obolibrary.org/obo/UBERON_0000160	denotes	intestine
T8923	2892-2898	http://purl.obolibrary.org/obo/UBERON_0002106	denotes	spleen
T8924	2900-2921	http://purl.obolibrary.org/obo/UBERON_0002509	denotes	mesenteric lymph node
T31393	2241-2247	http://purl.obolibrary.org/obo/UBERON_0002106	denotes	spleen
T31394	2249-2270	http://purl.obolibrary.org/obo/UBERON_0002509	denotes	mesenteric lymph node
T31395	2260-2265	http://purl.obolibrary.org/obo/UBERON_0002391	denotes	lymph
T31396	2260-2270	http://purl.obolibrary.org/obo/UBERON_0000029	denotes	lymph node
T31397	2282-2288	http://purl.obolibrary.org/obo/UBERON_0000957	denotes	lamina
T31398	2282-2296	http://purl.obolibrary.org/obo/UBERON_0000030	denotes	lamina propria
T31399	2304-2319	http://purl.obolibrary.org/obo/UBERON_0002108	denotes	small intestine
T31400	2310-2319	http://purl.obolibrary.org/obo/UBERON_0000160	denotes	intestine

GO-BP

Id	Subject	Object	Predicate	Lexical cue
T9988	75-95	http://purl.obolibrary.org/obo/GO_0050821	denotes	proteins, stabilizes
T9989	2630-2643	http://purl.obolibrary.org/obo/GO_0006351	denotes	transcription

GO-MF

Id	Subject	Object	Predicate	Lexical cue
T10088	114-121	http://purl.obolibrary.org/obo/GO_0005488	denotes	binding
T10089	1335-1342	http://purl.obolibrary.org/obo/GO_0005488	denotes	binding
T10090	1335-1349	http://purl.obolibrary.org/obo/GO_0003677	denotes	binding to DNA
T10091	1480-1484	http://purl.obolibrary.org/obo/GO_0005136	denotes	IL-4
T31897	1785-1789	http://purl.obolibrary.org/obo/GO_0005134	denotes	IL-2

GO-CC

Id	Subject	Object	Predicate	Lexical cue
T10092	314-319	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T10093	434-439	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T10094	575-580	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T10095	755-760	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T10096	900-905	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T31898	1587-1592	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T31899	1628-1633	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T31900	1671-1676	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T31901	1885-1890	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T31902	2046-2051	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T31903	2183-2188	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T31904	2226-2231	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T31905	1953-1966	http://purl.obolibrary.org/obo/GO_0005622	denotes	intracellular
T10097	988-993	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T10098	1093-1098	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T10099	1252-1257	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T10100	1396-1401	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T10101	2695-2700	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T10102	2713-2718	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T10103	2776-2781	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T10104	2883-2888	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T10105	3068-3073	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T10106	3199-3204	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T10107	3227-3232	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T10108	3348-3353	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T10109	819-832	http://purl.obolibrary.org/obo/GO_0005622	denotes	intracellular

sentences

Id	Subject	Object	Predicate	Lexical cue
T9034	0-38	Sentence	denotes	Role of CBFβ in the induction of Foxp3
T9035	39-165	Sentence	denotes	CBFβ, a common cofactor of all RUNX proteins, stabilizes and increases the binding of the runt domain to target DNA sequences.
T9036	166-362	Sentence	denotes	To target all Runx proteins that might be involved in the induction of Foxp3, we used mice in which loxP-flanked Cbfb alleles were inactivated in T cells through expression of a CD4-cre transgene.
T9037	363-460	Sentence	denotes	Retinoic acid and TGF-β synergize in the induction of Foxp3 in naive T cells (Kang et al., 2007).
T9038	461-728	Sentence	denotes	To investigate whether Runx-mediated induction of Foxp3 is dependent on the expression of CBFβ, naive CD4+ CD8− T cells from CbfbF/F CD4-cre and control CbfbF/+ CD4-cre mice were stimulated with anti-CD3/28 mAbs, retinoic acid, and increasing concentrations of TGF-β.
T9039	729-860	Sentence	denotes	After 3 d in culture, the cells were restimulated with PMA and ionomycin and analyzed for intracellular Foxp3 and IFN-γ expression.
T9040	861-994	Sentence	denotes	TGF-β induced Foxp3 in CbfbF/+ CD4-cre cells in a dose dependent manner, and this was significantly reduced in CbfbF/F CD4-cre cells.
T9041	995-1172	Sentence	denotes	Retinoic acid enhanced Foxp3 expression even in 20 pg/ml of TGF-β and more than 95% of the CD4+ T cells from CbfbF/+ CD4-cre mice became Foxp3+ in 100 and 500 pg/ml TGF-β doses.
T9042	1173-1413	Sentence	denotes	The induction of Foxp3 was again significantly lower in CbfbF/F CD4-cre CD4+ T cells even in the presence of retinoic acid, demonstrating that deficiency in Runx binding to DNA affects the TGF-β induction of Foxp3 in T reg cells (Fig. 5 A).
T9043	1414-1522	Sentence	denotes	There was no difference in the induction of Foxp3 when endogenous IL-4 and IFN-γ were neutralized (Fig. S6).
T9044	2607-2732	Sentence	denotes	The importance of RUNX transcription factors for the in vivo conversion of naive CD4+ T cells into iT reg cells was examined.
T9045	2733-2863	Sentence	denotes	Control CbfbF/F or CbfbF/F CD4-cre naive T cells, harboring a Foxp3-IRES-GFP allele were adoptively transferred into Rag2−/− mice.
T9046	2864-3015	Sentence	denotes	6 wk later, CD4+ T cells in spleen, mesenteric lymph node, and lamina propria of the small intestine were analyzed for Foxp3-GFP expression (Fig. 5 B).
T9047	3016-3251	Sentence	denotes	There was a consistently lower percentage of CD4+ T cells that had developed Foxp3 expression in the mesenteric lymph node and lamina propria of mice transferred with CbfbF/F CD4-cre cells compared with control cells (Fig. 5, B and C).
T9048	3252-3354	Sentence	denotes	These data affirm the significance of RUNX proteins for the in vivo generation of CD4+ Foxp3+ T cells.
T31435	1534-1858	Sentence	denotes	Diminished capacity of Cbfb-deficient CD4-cre mice T cells in the generation of Foxp3+ CD4+ T cells. (A) FACS-purified naive CD4+ CD8− T cells from CbfbF/F CD4-cre and control CbfbF/+ CD4-cre mice were activated in vitro with anti-CD3/28 mAb, 50 U/ml IL-2, ± 10 nM retinoic acid (RA), and increasing concentrations of TGF-β.
T31436	1859-1994	Sentence	denotes	After 3 d in culture, the cells were restimulated with PMA + ionomycin, and then analyzed for intracellular Foxp3 and IFN-γ expression.
T31437	1995-2203	Sentence	denotes	One of five experiments is shown. (B) Naive CD4+ T cells from Cbfb CD4-cre or control mice (harboring a Foxp3-IRES-GFP allele) were adoptively transferred into Rag-deficient mice (5 × 106 cells per transfer).
T31438	2204-2364	Sentence	denotes	6 wk later, TCRβ+CD4+ cells from the spleen, mesenteric lymph node (MLN), and lamina propria of the small intestine (LP) were analyzed for Foxp3-GFP expression.
T31439	2365-2468	Sentence	denotes	Results from one of four CbfbF/F CD4-cre and control CbfbF/+ CD4-cre mice with same findings are shown.
T31440	2469-2604	Sentence	denotes	The data from four sets of mice is shown in C. Statistical analysis was performed with Mann-Whitney U test. *, P < 0.05 between groups.
T126	0-38	Sentence	denotes	Role of CBFβ in the induction of Foxp3
T127	39-165	Sentence	denotes	CBFβ, a common cofactor of all RUNX proteins, stabilizes and increases the binding of the runt domain to target DNA sequences.
T128	166-362	Sentence	denotes	To target all Runx proteins that might be involved in the induction of Foxp3, we used mice in which loxP-flanked Cbfb alleles were inactivated in T cells through expression of a CD4-cre transgene.
T129	363-460	Sentence	denotes	Retinoic acid and TGF-β synergize in the induction of Foxp3 in naive T cells (Kang et al., 2007).
T130	461-728	Sentence	denotes	To investigate whether Runx-mediated induction of Foxp3 is dependent on the expression of CBFβ, naive CD4+ CD8− T cells from CbfbF/F CD4-cre and control CbfbF/+ CD4-cre mice were stimulated with anti-CD3/28 mAbs, retinoic acid, and increasing concentrations of TGF-β.
T131	729-860	Sentence	denotes	After 3 d in culture, the cells were restimulated with PMA and ionomycin and analyzed for intracellular Foxp3 and IFN-γ expression.
T132	861-994	Sentence	denotes	TGF-β induced Foxp3 in CbfbF/+ CD4-cre cells in a dose dependent manner, and this was significantly reduced in CbfbF/F CD4-cre cells.
T133	995-1172	Sentence	denotes	Retinoic acid enhanced Foxp3 expression even in 20 pg/ml of TGF-β and more than 95% of the CD4+ T cells from CbfbF/+ CD4-cre mice became Foxp3+ in 100 and 500 pg/ml TGF-β doses.
T134	1173-1413	Sentence	denotes	The induction of Foxp3 was again significantly lower in CbfbF/F CD4-cre CD4+ T cells even in the presence of retinoic acid, demonstrating that deficiency in Runx binding to DNA affects the TGF-β induction of Foxp3 in T reg cells (Fig. 5 A).
T135	1414-1522	Sentence	denotes	There was no difference in the induction of Foxp3 when endogenous IL-4 and IFN-γ were neutralized (Fig. S6).
T136	1523-1532	Sentence	denotes	Figure 5.
T137	1534-1858	Sentence	denotes	Diminished capacity of Cbfb-deficient CD4-cre mice T cells in the generation of Foxp3+ CD4+ T cells. (A) FACS-purified naive CD4+ CD8− T cells from CbfbF/F CD4-cre and control CbfbF/+ CD4-cre mice were activated in vitro with anti-CD3/28 mAb, 50 U/ml IL-2, ± 10 nM retinoic acid (RA), and increasing concentrations of TGF-β.
T138	1859-1994	Sentence	denotes	After 3 d in culture, the cells were restimulated with PMA + ionomycin, and then analyzed for intracellular Foxp3 and IFN-γ expression.
T139	1995-2203	Sentence	denotes	One of five experiments is shown. (B) Naive CD4+ T cells from Cbfb CD4-cre or control mice (harboring a Foxp3-IRES-GFP allele) were adoptively transferred into Rag-deficient mice (5 × 106 cells per transfer).
T140	2204-2364	Sentence	denotes	6 wk later, TCRβ+CD4+ cells from the spleen, mesenteric lymph node (MLN), and lamina propria of the small intestine (LP) were analyzed for Foxp3-GFP expression.
T141	2365-2468	Sentence	denotes	Results from one of four CbfbF/F CD4-cre and control CbfbF/+ CD4-cre mice with same findings are shown.
T142	2469-2515	Sentence	denotes	The data from four sets of mice is shown in C.
T143	2516-2604	Sentence	denotes	Statistical analysis was performed with Mann-Whitney U test. *, P < 0.05 between groups.
T144	2607-2732	Sentence	denotes	The importance of RUNX transcription factors for the in vivo conversion of naive CD4+ T cells into iT reg cells was examined.
T145	2733-2863	Sentence	denotes	Control CbfbF/F or CbfbF/F CD4-cre naive T cells, harboring a Foxp3-IRES-GFP allele were adoptively transferred into Rag2−/− mice.
T146	2864-3015	Sentence	denotes	6 wk later, CD4+ T cells in spleen, mesenteric lymph node, and lamina propria of the small intestine were analyzed for Foxp3-GFP expression (Fig. 5 B).
T147	3016-3251	Sentence	denotes	There was a consistently lower percentage of CD4+ T cells that had developed Foxp3 expression in the mesenteric lymph node and lamina propria of mice transferred with CbfbF/F CD4-cre cells compared with control cells (Fig. 5, B and C).
T148	3252-3354	Sentence	denotes	These data affirm the significance of RUNX proteins for the in vivo generation of CD4+ Foxp3+ T cells.

events-check-again

Id	Subject	Object	Predicate	Lexical cue	Negation	Speculation
T10110	0-4	Positive_regulation	denotes	Role		true
T10111	8-12	Protein	denotes	CBFβ
T10112	20-29	Gene_expression	denotes	induction
T10113	33-38	Protein	denotes	Foxp3
T10114	39-43	Protein	denotes	CBFβ
T10115	70-74	Protein	denotes	RUNX
T10116	180-184	Protein	denotes	Runx
T10117	208-216	Regulation	denotes	involved		true
T10118	224-233	Positive_regulation	denotes	induction
T10119	237-242	Protein	denotes	Foxp3
T10120	279-283	Protein	denotes	Cbfb
T10121	297-308	Negative_regulation	denotes	inactivated
T10122	328-338	Gene_expression	denotes	expression
T10123	344-351	Protein	denotes	CD4-cre
T10124	381-386	Protein	denotes	TGF-β
T10125	387-396	Positive_regulation	denotes	synergize
T10126	404-413	Gene_expression	denotes	induction
T10127	417-422	Protein	denotes	Foxp3
T10128	484-488	Protein	denotes	Runx
T10129	489-497	Positive_regulation	denotes	mediated
T10130	498-507	Gene_expression	denotes	induction
T10131	511-516	Protein	denotes	Foxp3
T10132	520-529	Positive_regulation	denotes	dependent		true
T10133	537-547	Gene_expression	denotes	expression
T10134	551-555	Protein	denotes	CBFβ
T10135	563-566	Protein	denotes	CD4
T10136	568-571	Protein	denotes	CD8
T10137	586-590	Protein	denotes	Cbfb
T10138	594-601	Protein	denotes	CD4-cre
T10139	614-618	Protein	denotes	Cbfb
T10140	622-629	Protein	denotes	CD4-cre
T10141	661-664	Protein	denotes	CD3
T10142	665-667	Protein	denotes	28
T10143	722-727	Protein	denotes	TGF-β
T10144	833-838	Protein	denotes	Foxp3
T10145	843-848	Protein	denotes	IFN-γ
T10146	849-859	Gene_expression	denotes	expression		true
T10147	849-859	Gene_expression	denotes	expression		true
T10148	861-866	Protein	denotes	TGF-β
T10149	867-874	Positive_regulation	denotes	induced
T10150	875-880	Protein	denotes	Foxp3
T10151	884-888	Protein	denotes	Cbfb
T10152	892-899	Protein	denotes	CD4-cre
T10153	961-968	Negative_regulation	denotes	reduced
T10154	972-976	Protein	denotes	Cbfb
T10155	980-987	Protein	denotes	CD4-cre
T10156	1009-1017	Positive_regulation	denotes	enhanced
T10157	1018-1023	Protein	denotes	Foxp3
T10158	1024-1034	Gene_expression	denotes	expression
T10159	1055-1060	Protein	denotes	TGF-β
T10160	1086-1089	Protein	denotes	CD4
T10161	1104-1108	Protein	denotes	Cbfb
T10162	1112-1119	Protein	denotes	CD4-cre
T10163	1132-1137	Protein	denotes	Foxp3
T10164	1160-1165	Protein	denotes	TGF-β
T10165	1177-1186	Gene_expression	denotes	induction
T10166	1190-1195	Protein	denotes	Foxp3
T10167	1220-1225	Negative_regulation	denotes	lower
T10168	1229-1233	Protein	denotes	Cbfb
T10169	1237-1244	Protein	denotes	CD4-cre
T10170	1245-1248	Protein	denotes	CD4
T10171	1330-1334	Protein	denotes	Runx
T10172	1335-1342	Binding	denotes	binding
T10173	1350-1357	Regulation	denotes	affects
T10174	1362-1367	Protein	denotes	TGF-β
T10175	1368-1377	Positive_regulation	denotes	induction
T10176	1381-1386	Protein	denotes	Foxp3
T10177	1427-1437	Regulation	denotes	difference	true
T10178	1427-1437	Regulation	denotes	difference	true
T10179	1445-1454	Gene_expression	denotes	induction
T10180	1458-1463	Protein	denotes	Foxp3
T10181	1480-1484	Protein	denotes	IL-4
T10182	1489-1494	Protein	denotes	IFN-γ
T10183	1500-1511	Negative_regulation	denotes	neutralized
T10184	1500-1511	Negative_regulation	denotes	neutralized
T10185	2625-2629	Protein	denotes	RUNX
T10186	2688-2691	Protein	denotes	CD4
T10187	2741-2745	Protein	denotes	Cbfb
T10188	2752-2756	Protein	denotes	Cbfb
T10189	2760-2767	Protein	denotes	CD4-cre
T10190	2795-2800	Protein	denotes	Foxp3
T10191	2806-2809	Protein	denotes	GFP
T10192	2850-2854	Protein	denotes	Rag2
T10193	2876-2879	Protein	denotes	CD4
T10194	2983-2992	Protein	denotes	Foxp3-GFP
T10195	2993-3003	Gene_expression	denotes	expression		true
T10196	3061-3064	Protein	denotes	CD4
T10197	3093-3098	Protein	denotes	Foxp3
T10198	3099-3109	Gene_expression	denotes	expression
T10199	3183-3187	Protein	denotes	Cbfb
T10200	3191-3198	Protein	denotes	CD4-cre
T10201	3274-3286	Positive_regulation	denotes	significance
T10202	3274-3286	Positive_regulation	denotes	significance
T10203	3290-3294	Protein	denotes	RUNX
T10204	3320-3330	Gene_expression	denotes	generation
T10205	3320-3330	Gene_expression	denotes	generation
T10206	3334-3337	Protein	denotes	CD4
T10207	3339-3344	Protein	denotes	Foxp3
T32006	1557-1561	Protein	denotes	Cbfb
T32007	1562-1571	Negative_regulation	denotes	deficient
T32008	1572-1579	Protein	denotes	CD4-cre
T32009	1614-1619	Protein	denotes	Foxp3
T32010	1621-1624	Protein	denotes	CD4
T32011	1659-1662	Protein	denotes	CD4
T32012	1664-1667	Protein	denotes	CD8
T32013	1682-1686	Protein	denotes	Cbfb
T32014	1690-1697	Protein	denotes	CD4-cre
T32015	1710-1714	Protein	denotes	Cbfb
T32016	1718-1725	Protein	denotes	CD4-cre
T32017	1765-1768	Protein	denotes	CD3
T32018	1769-1771	Protein	denotes	28
T32019	1785-1789	Protein	denotes	IL-2
T32020	1852-1857	Protein	denotes	TGF-β
T32021	1967-1972	Protein	denotes	Foxp3
T32022	1977-1982	Protein	denotes	IFN-γ
T32023	1983-1993	Gene_expression	denotes	expression		true
T32024	1983-1993	Gene_expression	denotes	expression		true
T32025	2039-2042	Protein	denotes	CD4
T32026	2057-2061	Protein	denotes	Cbfb
T32027	2062-2069	Protein	denotes	CD4-cre
T32028	2099-2104	Protein	denotes	Foxp3
T32029	2110-2113	Protein	denotes	GFP
T32030	2155-2158	Protein	denotes	Rag
T32031	2159-2168	Negative_regulation	denotes	deficient
T32032	2216-2220	Protein	denotes	TCRβ
T32033	2221-2224	Protein	denotes	CD4
T32034	2343-2352	Protein	denotes	Foxp3-GFP
T32035	2353-2363	Gene_expression	denotes	expression		true
T32036	2390-2394	Protein	denotes	Cbfb
T32037	2398-2405	Protein	denotes	CD4-cre
T32038	2418-2422	Protein	denotes	Cbfb
T32039	2426-2433	Protein	denotes	CD4-cre
R8037	T10111	T10110	causeOf	CBFβ,Role
R8038	T10112	T10110	themeOf	induction,Role
R8039	T10113	T10112	themeOf	Foxp3,induction
R8040	T10116	T10117	causeOf	Runx,involved
R8041	T10118	T10117	themeOf	induction,involved
R8042	T10119	T10118	themeOf	Foxp3,induction
R8043	T10120	T10121	themeOf	Cbfb,inactivated
R8044	T10123	T10122	themeOf	CD4-cre,expression
R8045	T10124	T10125	causeOf	TGF-β,synergize
R8046	T10126	T10125	themeOf	induction,synergize
R8047	T10127	T10126	themeOf	Foxp3,induction
R8048	T10128	T10129	causeOf	Runx,mediated
R8049	T10130	T10129	themeOf	induction,mediated
R8050	T10130	T10132	themeOf	induction,dependent
R8051	T10131	T10130	themeOf	Foxp3,induction
R8052	T10133	T10132	causeOf	expression,dependent
R8053	T10134	T10133	themeOf	CBFβ,expression
R8054	T10144	T10147	themeOf	Foxp3,expression
R8055	T10145	T10146	themeOf	IFN-γ,expression
R8056	T10148	T10149	causeOf	TGF-β,induced
R8057	T10149	T10153	themeOf	induced,reduced
R8058	T10150	T10149	themeOf	Foxp3,induced
R8059	T10157	T10158	themeOf	Foxp3,expression
R8060	T10158	T10156	themeOf	expression,enhanced
R8061	T10159	T10156	causeOf	TGF-β,enhanced
R8062	T10165	T10167	themeOf	induction,lower
R8063	T10166	T10165	themeOf	Foxp3,induction
R8064	T10171	T10172	themeOf	Runx,binding
R8065	T10172	T10173	causeOf	binding,affects
R8066	T10174	T10175	causeOf	TGF-β,induction
R8067	T10175	T10173	themeOf	induction,affects
R8068	T10176	T10175	themeOf	Foxp3,induction
R8069	T10179	T10178	themeOf	induction,difference
R8070	T10179	T10177	themeOf	induction,difference
R8071	T10180	T10179	themeOf	Foxp3,induction
R8072	T10181	T10184	themeOf	IL-4,neutralized
R8073	T10182	T10183	themeOf	IFN-γ,neutralized
R8074	T10183	T10177	causeOf	neutralized,difference
R8075	T10184	T10178	causeOf	neutralized,difference
R8076	T10194	T10195	themeOf	Foxp3-GFP,expression
R8077	T10197	T10198	themeOf	Foxp3,expression
R8078	T10203	T10201	causeOf	RUNX,significance
R8079	T10203	T10202	causeOf	RUNX,significance
R8080	T10204	T10201	themeOf	generation,significance
R8081	T10205	T10202	themeOf	generation,significance
R8082	T10206	T10204	themeOf	CD4,generation
R8083	T10207	T10205	themeOf	Foxp3,generation
R24550	T32006	T32007	themeOf	Cbfb,deficient
R24551	T32021	T32024	themeOf	Foxp3,expression
R24552	T32022	T32023	themeOf	IFN-γ,expression
R24553	T32030	T32031	themeOf	Rag,deficient
R24554	T32034	T32035	themeOf	Foxp3-GFP,expression

bionlp-st-ge-2016-reference-tees

Id	Subject	Object	Predicate	Lexical cue
T10211	114-121	Binding	denotes	binding
T10208	8-12	Protein	denotes	CBFβ
T10209	39-43	Protein	denotes	CBFβ
T10210	70-83	Protein	denotes	RUNX proteins
T10212	180-193	Protein	denotes	Runx proteins
T10213	237-242	Protein	denotes	Foxp3
T10214	279-291	Protein	denotes	Cbfb alleles
T10215	344-347	Protein	denotes	CD4
T10216	348-361	Protein	denotes	cre transgene
T10217	169-175	Gene_expression	denotes	target
T10218	224-233	Positive_regulation	denotes	induction
T10219	297-308	Negative_regulation	denotes	inactivated
T10318	328-338	Gene_expression	denotes	expression
T10319	208-216	Regulation	denotes	involved
T10320	297-308	Negative_regulation	denotes	inactivated
T10321	363-396	Protein	denotes	Retinoic acid and TGF-β synergize
T10322	417-422	Protein	denotes	Foxp3
T10323	404-413	Positive_regulation	denotes	induction
T10324	511-516	Protein	denotes	Foxp3
T10325	551-555	Protein	denotes	CBFβ
T10326	563-566	Protein	denotes	CD4
T10327	568-571	Protein	denotes	CD8
T10328	586-597	Protein	denotes	CbfbF/F CD4
T10329	598-601	Protein	denotes	cre
T10330	614-629	Protein	denotes	CbfbF/+ CD4-cre
T10331	722-727	Protein	denotes	TGF-β
T10332	498-507	Positive_regulation	denotes	induction
T10333	537-547	Gene_expression	denotes	expression
T10334	833-838	Protein	denotes	Foxp3
T10335	843-848	Protein	denotes	IFN-γ
T10336	849-859	Gene_expression	denotes	expression
T10337	849-859	Gene_expression	denotes	expression
T10338	861-866	Protein	denotes	TGF-β
T10339	875-880	Protein	denotes	Foxp3
T10340	884-895	Protein	denotes	CbfbF/+ CD4
T10341	896-899	Protein	denotes	cre
T10342	972-979	Protein	denotes	CbfbF/F
T10343	980-983	Protein	denotes	CD4
T10344	867-874	Positive_regulation	denotes	induced
T10345	984-987	Gene_expression	denotes	cre
T10346	984-987	Gene_expression	denotes	cre
T10347	1018-1023	Protein	denotes	Foxp3
T10348	1055-1060	Protein	denotes	TGF-β
T10349	1086-1090	Protein	denotes	CD4+
T10350	1104-1115	Protein	denotes	CbfbF/+ CD4
T10351	1116-1119	Protein	denotes	cre
T10352	1132-1138	Protein	denotes	Foxp3+
T10353	1024-1034	Gene_expression	denotes	expression
T10354	1009-1017	Positive_regulation	denotes	enhanced
T10355	1190-1195	Protein	denotes	Foxp3
T10356	1229-1244	Protein	denotes	CbfbF/F CD4-cre
T10357	1245-1249	Protein	denotes	CD4+
T10358	1330-1334	Protein	denotes	Runx
T10359	1362-1367	Protein	denotes	TGF-β
T10360	1381-1386	Protein	denotes	Foxp3
T10361	1177-1186	Positive_regulation	denotes	induction
T10362	1220-1225	Negative_regulation	denotes	lower
T10363	1335-1342	Binding	denotes	binding
T10364	1368-1377	Positive_regulation	denotes	induction
T10365	1316-1326	Negative_regulation	denotes	deficiency
T10366	1350-1357	Regulation	denotes	affects
T10367	1458-1463	Protein	denotes	Foxp3
T10368	1480-1484	Protein	denotes	IL-4
T10369	1489-1494	Protein	denotes	IFN-γ
T10370	1445-1454	Positive_regulation	denotes	induction
T10371	1500-1511	Negative_regulation	denotes	neutralized
T10372	1500-1511	Negative_regulation	denotes	neutralized
T10373	1427-1437	Regulation	denotes	difference
T10374	2625-2651	Protein	denotes	RUNX transcription factors
T10375	2688-2692	Protein	denotes	CD4+
T10376	2741-2748	Protein	denotes	CbfbF/F
T10377	2752-2763	Protein	denotes	CbfbF/F CD4
T10378	2764-2767	Protein	denotes	cre
T10379	2795-2800	Protein	denotes	Foxp3
T10380	2801-2805	Protein	denotes	IRES
T10381	2806-2809	Protein	denotes	GFP
T10382	2850-2854	Protein	denotes	Rag2
T10383	2876-2880	Protein	denotes	CD4+
T10384	2983-2988	Protein	denotes	Foxp3
T10385	2989-2992	Protein	denotes	GFP
T10386	2993-3003	Gene_expression	denotes	expression
T10387	2993-3003	Gene_expression	denotes	expression
T10388	3061-3065	Protein	denotes	CD4+
T10389	3093-3098	Protein	denotes	Foxp3
T10390	3183-3190	Protein	denotes	CbfbF/F
T10391	3191-3194	Protein	denotes	CD4
T10392	3099-3109	Gene_expression	denotes	expression
T10393	3290-3303	Protein	denotes	RUNX proteins
T10394	3334-3337	Protein	denotes	CD4
T10395	3339-3344	Protein	denotes	Foxp3
T31940	1557-1561	Protein	denotes	Cbfb
T31941	1572-1575	Protein	denotes	CD4
T31942	1614-1619	Protein	denotes	Foxp3
T31943	1621-1625	Protein	denotes	CD4+
T31944	1562-1571	Negative_regulation	denotes	deficient
T31945	1659-1662	Protein	denotes	CD4
T31946	1664-1667	Protein	denotes	CD8
T31947	1682-1693	Protein	denotes	CbfbF/F CD4
T31948	1694-1697	Protein	denotes	cre
T31949	1710-1725	Protein	denotes	CbfbF/+ CD4-cre
T31950	1852-1857	Protein	denotes	TGF-β
T31951	1967-1972	Protein	denotes	Foxp3
T31952	1977-1982	Protein	denotes	IFN-γ
T31953	1983-1993	Gene_expression	denotes	expression
T31954	1983-1993	Gene_expression	denotes	expression
T31955	2039-2043	Protein	denotes	CD4+
T31956	2057-2065	Protein	denotes	Cbfb CD4
T31957	2066-2069	Protein	denotes	cre
T31958	2099-2104	Protein	denotes	Foxp3
T31959	2105-2109	Protein	denotes	IRES
T31960	2110-2113	Protein	denotes	GFP
T31961	2155-2158	Protein	denotes	Rag
T31962	2159-2168	Negative_regulation	denotes	deficient
T31963	2216-2220	Protein	denotes	TCRβ
T31964	2221-2224	Protein	denotes	CD4
T31965	2343-2348	Protein	denotes	Foxp3
T31966	2349-2352	Protein	denotes	GFP
T31967	2353-2363	Gene_expression	denotes	expression
T31968	2353-2363	Gene_expression	denotes	expression
T31969	2390-2401	Protein	denotes	CbfbF/F CD4
T31970	2402-2405	Protein	denotes	cre
T31971	2418-2433	Protein	denotes	CbfbF/+ CD4-cre
R8084	T10209	T10211	themeOf	CBFβ,binding
R8085	T10212	T10217	themeOf	Runx proteins,target
R8086	T10212	T10319	causeOf	Runx proteins,involved
R8087	T10213	T10218	themeOf	Foxp3,induction
R8088	T10214	T10219	themeOf	Cbfb alleles,inactivated
R8089	T10216	T10318	themeOf	cre transgene,expression
R8090	T10218	T10319	themeOf	induction,involved
R8138	T10318	T10320	themeOf	expression,inactivated
R8139	T10322	T10323	themeOf	Foxp3,induction
R8140	T10324	T10332	themeOf	Foxp3,induction
R8141	T10325	T10333	themeOf	CBFβ,expression
R8142	T10334	T10336	themeOf	Foxp3,expression
R8143	T10335	T10337	themeOf	IFN-γ,expression
R8144	T10338	T10344	causeOf	TGF-β,induced
R8145	T10339	T10344	themeOf	Foxp3,induced
R8146	T10342	T10345	themeOf	CbfbF/F,cre
R8147	T10343	T10346	themeOf	CD4,cre
R8148	T10347	T10353	themeOf	Foxp3,expression
R8149	T10348	T10354	causeOf	TGF-β,enhanced
R8150	T10353	T10354	themeOf	expression,enhanced
R8151	T10355	T10361	themeOf	Foxp3,induction
R8152	T10358	T10363	themeOf	Runx,binding
R8153	T10359	T10364	causeOf	TGF-β,induction
R8154	T10360	T10364	themeOf	Foxp3,induction
R8155	T10361	T10362	themeOf	induction,lower
R8156	T10363	T10365	themeOf	binding,deficiency
R8157	T10364	T10366	themeOf	induction,affects
R8158	T10365	T10366	causeOf	deficiency,affects
R8159	T10367	T10370	themeOf	Foxp3,induction
R8160	T10368	T10371	themeOf	IL-4,neutralized
R8161	T10369	T10372	themeOf	IFN-γ,neutralized
R24539	T31940	T31944	themeOf	Cbfb,deficient
R24540	T31951	T31953	themeOf	Foxp3,expression
R24541	T31952	T31954	themeOf	IFN-γ,expression
R24542	T31961	T31962	themeOf	Rag,deficient
R24543	T31965	T31967	themeOf	Foxp3,expression
R24544	T31966	T31968	themeOf	GFP,expression
R8162	T10370	T10373	themeOf	induction,difference
R8163	T10384	T10386	themeOf	Foxp3,expression
R8164	T10385	T10387	themeOf	GFP,expression
R8165	T10389	T10392	themeOf	Foxp3,expression

bionlp-st-ge-2016-reference

Id	Subject	Object	Predicate	Lexical cue	Negation	Speculation
T8936	0-4	Positive_regulation	denotes	Role		true
T8937	8-12	Protein	denotes	CBFβ
T8943	208-216	Regulation	denotes	involved		true
T8944	224-233	Positive_regulation	denotes	induction
T8945	237-242	Protein	denotes	Foxp3
T8946	279-283	Protein	denotes	Cbfb
T8947	297-308	Negative_regulation	denotes	inactivated
T8948	328-338	Gene_expression	denotes	expression
T8949	344-351	Protein	denotes	CD4-cre
T8950	381-386	Protein	denotes	TGF-β
T8951	387-396	Positive_regulation	denotes	synergize
T8952	404-413	Gene_expression	denotes	induction
T8953	417-422	Protein	denotes	Foxp3
T8954	484-488	Protein	denotes	Runx
T8955	489-497	Positive_regulation	denotes	mediated
T8956	498-507	Gene_expression	denotes	induction
T8957	511-516	Protein	denotes	Foxp3
T8958	520-529	Positive_regulation	denotes	dependent		true
T8959	537-547	Gene_expression	denotes	expression
T8960	551-555	Protein	denotes	CBFβ
T8961	563-566	Protein	denotes	CD4
T8962	568-571	Protein	denotes	CD8
T8963	586-590	Protein	denotes	Cbfb
T8964	594-601	Protein	denotes	CD4-cre
T8965	614-618	Protein	denotes	Cbfb
T8966	622-629	Protein	denotes	CD4-cre
T8967	661-664	Protein	denotes	CD3
T8968	665-667	Protein	denotes	28
T8969	722-727	Protein	denotes	TGF-β
T8970	833-838	Protein	denotes	Foxp3
T8971	843-848	Protein	denotes	IFN-γ
T8972	849-859	Gene_expression	denotes	expression		true
T8973	849-859	Gene_expression	denotes	expression		true
T8974	861-866	Protein	denotes	TGF-β
T8975	867-874	Positive_regulation	denotes	induced
T8976	875-880	Protein	denotes	Foxp3
T8977	884-888	Protein	denotes	Cbfb
T8978	892-899	Protein	denotes	CD4-cre
T8979	961-968	Negative_regulation	denotes	reduced
T8980	972-976	Protein	denotes	Cbfb
T8981	980-987	Protein	denotes	CD4-cre
T8982	1009-1017	Positive_regulation	denotes	enhanced
T8983	1018-1023	Protein	denotes	Foxp3
T8984	1024-1034	Gene_expression	denotes	expression
T8985	1055-1060	Protein	denotes	TGF-β
T8986	1086-1089	Protein	denotes	CD4
T8987	1104-1108	Protein	denotes	Cbfb
T8988	1112-1119	Protein	denotes	CD4-cre
T8989	1132-1137	Protein	denotes	Foxp3
T8990	1160-1165	Protein	denotes	TGF-β
T8991	1177-1186	Gene_expression	denotes	induction
T8992	1190-1195	Protein	denotes	Foxp3
T8993	1220-1225	Negative_regulation	denotes	lower
T8994	1229-1233	Protein	denotes	Cbfb
T8995	1237-1244	Protein	denotes	CD4-cre
T8996	1245-1248	Protein	denotes	CD4
T8997	1330-1334	Protein	denotes	Runx
T8998	1335-1342	Binding	denotes	binding
T8999	1350-1357	Regulation	denotes	affects
T9000	1362-1367	Protein	denotes	TGF-β
T9001	1368-1377	Positive_regulation	denotes	induction
T9002	1381-1386	Protein	denotes	Foxp3
T9003	1427-1437	Regulation	denotes	difference	true
T9004	1427-1437	Regulation	denotes	difference	true
T9005	1445-1454	Gene_expression	denotes	induction
T9006	1458-1463	Protein	denotes	Foxp3
T9007	1480-1484	Protein	denotes	IL-4
T9008	1489-1494	Protein	denotes	IFN-γ
T9009	1500-1511	Negative_regulation	denotes	neutralized
T9010	1500-1511	Negative_regulation	denotes	neutralized
T9011	2625-2629	Protein	denotes	RUNX
T9012	2688-2691	Protein	denotes	CD4
T9013	2741-2745	Protein	denotes	Cbfb
T9014	2752-2756	Protein	denotes	Cbfb
T9015	2760-2767	Protein	denotes	CD4-cre
T9016	2795-2800	Protein	denotes	Foxp3
T9017	2806-2809	Protein	denotes	GFP
T9018	2850-2854	Protein	denotes	Rag2
T9019	2876-2879	Protein	denotes	CD4
T9020	2983-2992	Protein	denotes	Foxp3-GFP
T9021	2993-3003	Gene_expression	denotes	expression		true
T9022	3061-3064	Protein	denotes	CD4
T9023	3093-3098	Protein	denotes	Foxp3
T9024	3099-3109	Gene_expression	denotes	expression
T9025	3183-3187	Protein	denotes	Cbfb
T9026	3191-3198	Protein	denotes	CD4-cre
T9027	3274-3286	Positive_regulation	denotes	significance
T9028	3274-3286	Positive_regulation	denotes	significance
T9029	3290-3294	Protein	denotes	RUNX
T9030	3320-3330	Gene_expression	denotes	generation
T9031	3320-3330	Gene_expression	denotes	generation
T9032	3334-3337	Protein	denotes	CD4
T9033	3339-3344	Protein	denotes	Foxp3
T31428	2221-2224	Protein	denotes	CD4
T31429	2343-2352	Protein	denotes	Foxp3-GFP
T31430	2353-2363	Gene_expression	denotes	expression		true
T31431	2390-2394	Protein	denotes	Cbfb
T31432	2398-2405	Protein	denotes	CD4-cre
T31433	2418-2422	Protein	denotes	Cbfb
T8938	20-29	Gene_expression	denotes	induction
T8939	33-38	Protein	denotes	Foxp3
T8940	39-43	Protein	denotes	CBFβ
T8941	70-74	Protein	denotes	RUNX
T8942	180-184	Protein	denotes	Runx
T31401	1557-1561	Protein	denotes	Cbfb
T31402	1562-1571	Negative_regulation	denotes	deficient
T31403	1572-1579	Protein	denotes	CD4-cre
T31404	1614-1619	Protein	denotes	Foxp3
T31405	1621-1624	Protein	denotes	CD4
T31406	1659-1662	Protein	denotes	CD4
T31407	1664-1667	Protein	denotes	CD8
T31408	1682-1686	Protein	denotes	Cbfb
T31409	1690-1697	Protein	denotes	CD4-cre
T31410	1710-1714	Protein	denotes	Cbfb
T31411	1718-1725	Protein	denotes	CD4-cre
T31412	1765-1768	Protein	denotes	CD3
T31413	1769-1771	Protein	denotes	28
T31414	1785-1789	Protein	denotes	IL-2
T31415	1852-1857	Protein	denotes	TGF-β
T31416	1967-1972	Protein	denotes	Foxp3
T31417	1977-1982	Protein	denotes	IFN-γ
T31418	1983-1993	Gene_expression	denotes	expression		true
T31419	1983-1993	Gene_expression	denotes	expression		true
T31420	2039-2042	Protein	denotes	CD4
T31421	2057-2061	Protein	denotes	Cbfb
T31422	2062-2069	Protein	denotes	CD4-cre
T31423	2099-2104	Protein	denotes	Foxp3
T31424	2110-2113	Protein	denotes	GFP
T31425	2155-2158	Protein	denotes	Rag
T31426	2159-2168	Negative_regulation	denotes	deficient
T31427	2216-2220	Protein	denotes	TCRβ
T31434	2426-2433	Protein	denotes	CD4-cre
R7100	T8949	T8948	themeOf	CD4-cre,expression
R7101	T8950	T8951	causeOf	TGF-β,synergize
R7102	T8952	T8951	themeOf	induction,synergize
R7103	T8953	T8952	themeOf	Foxp3,induction
R7104	T8954	T8955	causeOf	Runx,mediated
R7105	T8956	T8955	themeOf	induction,mediated
R7106	T8956	T8958	themeOf	induction,dependent
R7107	T8957	T8956	themeOf	Foxp3,induction
R7108	T8959	T8958	causeOf	expression,dependent
R7109	T8960	T8959	themeOf	CBFβ,expression
R7110	T8970	T8973	themeOf	Foxp3,expression
R7111	T8971	T8972	themeOf	IFN-γ,expression
R7112	T8974	T8975	causeOf	TGF-β,induced
R7113	T8975	T8979	themeOf	induced,reduced
R7114	T8976	T8975	themeOf	Foxp3,induced
R7115	T8983	T8984	themeOf	Foxp3,expression
R7116	T8984	T8982	themeOf	expression,enhanced
R7117	T8985	T8982	causeOf	TGF-β,enhanced
R7118	T8991	T8993	themeOf	induction,lower
R7119	T8992	T8991	themeOf	Foxp3,induction
R7120	T8997	T8998	themeOf	Runx,binding
R7121	T8998	T8999	causeOf	binding,affects
R7122	T9000	T9001	causeOf	TGF-β,induction
R7123	T9001	T8999	themeOf	induction,affects
R7124	T9002	T9001	themeOf	Foxp3,induction
R7125	T9005	T9004	themeOf	induction,difference
R7126	T9005	T9003	themeOf	induction,difference
R7127	T9006	T9005	themeOf	Foxp3,induction
R7128	T9007	T9010	themeOf	IL-4,neutralized
R7129	T9008	T9009	themeOf	IFN-γ,neutralized
R7130	T9009	T9003	causeOf	neutralized,difference
R7131	T9010	T9004	causeOf	neutralized,difference
R7132	T9020	T9021	themeOf	Foxp3-GFP,expression
R7133	T9023	T9024	themeOf	Foxp3,expression
R7134	T9029	T9027	causeOf	RUNX,significance
R7135	T9029	T9028	causeOf	RUNX,significance
R7136	T9030	T9027	themeOf	generation,significance
R7137	T9031	T9028	themeOf	generation,significance
R7138	T9032	T9030	themeOf	CD4,generation
R7139	T9033	T9031	themeOf	Foxp3,generation
R7093	T8937	T8936	causeOf	CBFβ,Role
R7094	T8938	T8936	themeOf	induction,Role
R7095	T8939	T8938	themeOf	Foxp3,induction
R7096	T8942	T8943	causeOf	Runx,involved
R7097	T8944	T8943	themeOf	induction,involved
R7098	T8945	T8944	themeOf	Foxp3,induction
R7099	T8946	T8947	themeOf	Cbfb,inactivated
R24106	T31401	T31402	themeOf	Cbfb,deficient
R24107	T31416	T31419	themeOf	Foxp3,expression
R24108	T31417	T31418	themeOf	IFN-γ,expression
R24109	T31425	T31426	themeOf	Rag,deficient
R24110	T31429	T31430	themeOf	Foxp3-GFP,expression

bionlp-st-ge-2016-uniprot

Id	Subject	Object	Predicate	Lexical cue
T9454	8-12	Q13951	denotes	CBFβ
T9455	33-38	Q9BZS1	denotes	Foxp3
T9456	39-43	Q13951	denotes	CBFβ
T9457	70-74	Q13950	denotes	RUNX
T9458	70-74	Q01196	denotes	RUNX
T9459	70-74	Q13761	denotes	RUNX
T9460	180-184	Q13950	denotes	Runx
T9461	180-184	Q13761	denotes	Runx
T9462	180-184	Q01196	denotes	Runx
T9463	237-242	Q9BZS1	denotes	Foxp3
T9464	279-283	Q13951	denotes	Cbfb
T9465	344-347	P01730	denotes	CD4
T9466	348-351	P06956	denotes	cre
T9467	381-386	P01137	denotes	TGF-β
T9468	417-422	Q9BZS1	denotes	Foxp3
T9469	484-488	Q13761	denotes	Runx
T9470	484-488	Q13950	denotes	Runx
T9471	484-488	Q01196	denotes	Runx
T9472	511-516	Q9BZS1	denotes	Foxp3
T9473	551-555	Q13951	denotes	CBFβ
T9474	563-566	P01730	denotes	CD4
T9475	568-571	P01732	denotes	CD8
T9476	568-571	P10966	denotes	CD8
T9477	594-597	P01730	denotes	CD4
T9478	598-601	P06956	denotes	cre
T9479	622-625	P01730	denotes	CD4
T9480	626-629	P06956	denotes	cre
T9481	661-664	P04234	denotes	CD3
T9482	661-664	P20963	denotes	CD3
T9483	661-664	P07766	denotes	CD3
T9531	3290-3294	Q13761	denotes	RUNX
T9532	3334-3337	P01730	denotes	CD4
T9533	3339-3344	Q9BZS1	denotes	Foxp3
T31638	1557-1561	Q13951	denotes	Cbfb
T31639	1572-1575	P01730	denotes	CD4
T31640	1576-1579	P06956	denotes	cre
T31641	1614-1619	Q9BZS1	denotes	Foxp3
T31642	1621-1624	P01730	denotes	CD4
T31643	1659-1662	P01730	denotes	CD4
T31644	1664-1667	P01732	denotes	CD8
T31645	1664-1667	P10966	denotes	CD8
T31646	1690-1693	P01730	denotes	CD4
T31647	1694-1697	P06956	denotes	cre
T31648	1718-1721	P01730	denotes	CD4
T31649	1722-1725	P06956	denotes	cre
T31650	1765-1768	P09693	denotes	CD3
T31651	1765-1768	P20963	denotes	CD3
T31652	1765-1768	P04234	denotes	CD3
T31653	1765-1768	P07766	denotes	CD3
T31654	1785-1789	P60568	denotes	IL-2
T31655	1852-1857	P01137	denotes	TGF-β
T31656	1967-1972	Q9BZS1	denotes	Foxp3
T31657	1977-1982	P01579	denotes	IFN-γ
T31658	2039-2042	P01730	denotes	CD4
T31659	2057-2061	Q13951	denotes	Cbfb
T31660	2062-2065	P01730	denotes	CD4
T31661	2066-2069	P06956	denotes	cre
T31662	2099-2104	Q9BZS1	denotes	Foxp3
T31663	2110-2113	Q9U6Y4	denotes	GFP
T31664	2221-2224	P01730	denotes	CD4
T31665	2343-2348	Q9BZS1	denotes	Foxp3
T31666	2349-2352	Q9U6Y4	denotes	GFP
T31667	2398-2401	P01730	denotes	CD4
T31668	2402-2405	P06956	denotes	cre
T31669	2426-2429	P01730	denotes	CD4
T31670	2430-2433	P06956	denotes	cre
T9484	661-664	P09693	denotes	CD3
T9485	722-727	P01137	denotes	TGF-β
T9486	833-838	Q9BZS1	denotes	Foxp3
T9487	843-848	P01579	denotes	IFN-γ
T9488	861-866	P01137	denotes	TGF-β
T9489	875-880	Q9BZS1	denotes	Foxp3
T9490	892-895	P01730	denotes	CD4
T9491	896-899	P06956	denotes	cre
T9492	980-983	P01730	denotes	CD4
T9493	984-987	P06956	denotes	cre
T9494	1018-1023	Q9BZS1	denotes	Foxp3
T9495	1055-1060	P01137	denotes	TGF-β
T9496	1086-1089	P01730	denotes	CD4
T9497	1112-1115	P01730	denotes	CD4
T9498	1116-1119	P06956	denotes	cre
T9499	1132-1137	Q9BZS1	denotes	Foxp3
T9500	1160-1165	P01137	denotes	TGF-β
T9501	1190-1195	Q9BZS1	denotes	Foxp3
T9502	1237-1240	P01730	denotes	CD4
T9503	1241-1244	P06956	denotes	cre
T9504	1245-1248	P01730	denotes	CD4
T9505	1330-1334	Q13761	denotes	Runx
T9506	1330-1334	Q13950	denotes	Runx
T9507	1330-1334	Q01196	denotes	Runx
T9508	1362-1367	P01137	denotes	TGF-β
T9509	1381-1386	Q9BZS1	denotes	Foxp3
T9510	1458-1463	Q9BZS1	denotes	Foxp3
T9511	1480-1484	P05112	denotes	IL-4
T9512	1489-1494	P01579	denotes	IFN-γ
T9513	2625-2629	Q01196	denotes	RUNX
T9514	2625-2629	Q13761	denotes	RUNX
T9515	2625-2629	Q13950	denotes	RUNX
T9516	2688-2691	P01730	denotes	CD4
T9517	2760-2763	P01730	denotes	CD4
T9518	2764-2767	P06956	denotes	cre
T9519	2795-2800	Q9BZS1	denotes	Foxp3
T9520	2806-2809	Q9U6Y4	denotes	GFP
T9521	2850-2854	P55895	denotes	Rag2
T9522	2876-2879	P01730	denotes	CD4
T9523	2983-2988	Q9BZS1	denotes	Foxp3
T9524	2989-2992	Q9U6Y4	denotes	GFP
T9525	3061-3064	P01730	denotes	CD4
T9526	3093-3098	Q9BZS1	denotes	Foxp3
T9527	3191-3194	P01730	denotes	CD4
T9528	3195-3198	P06956	denotes	cre
T9529	3290-3294	Q13950	denotes	RUNX
T9530	3290-3294	Q01196	denotes	RUNX

test2

Id	Subject	Object	Predicate	Lexical cue	Negation	Speculation
T8832	8-12	Protein	denotes	CBFβ		true
T8833	20-29	Positive_regulation	denotes	induction
T8834	33-38	Protein	denotes	Foxp3		true
T8835	39-43	Protein	denotes	CBFβ
T8836	70-74	Protein	denotes	RUNX
T8837	100-109	Positive_regulation	denotes	increases
T8838	114-121	Binding	denotes	binding
T8839	134-140	Entity	denotes	domain
T8840	180-184	Protein	denotes	Runx
T8841	208-216	Regulation	denotes	involved
T8842	224-233	Positive_regulation	denotes	induction		true
T8843	237-242	Protein	denotes	Foxp3
T8844	279-283	Protein	denotes	Cbfb		true
T8845	328-338	Gene_expression	denotes	expression		true
T8846	344-351	Protein	denotes	CD4-cre
T8847	381-386	Protein	denotes	TGF-β
T8848	387-396	Positive_regulation	denotes	synergize
T8849	404-413	Positive_regulation	denotes	induction
T8850	417-422	Protein	denotes	Foxp3
T8851	484-488	Protein	denotes	Runx
T8852	489-497	Positive_regulation	denotes	mediated
T8853	498-507	Positive_regulation	denotes	induction
T8854	511-516	Protein	denotes	Foxp3
T8855	520-529	Positive_regulation	denotes	dependent	true
T8856	537-547	Gene_expression	denotes	expression
T8857	551-555	Protein	denotes	CBFβ
T8858	563-566	Protein	denotes	CD4	true
T8859	568-571	Protein	denotes	CD8
T8860	586-591	Protein	denotes	CbfbF		true
T8861	594-601	Protein	denotes	CD4-cre
T8862	614-619	Protein	denotes	CbfbF
T8863	622-629	Protein	denotes	CD4-cre
T8864	661-664	Protein	denotes	CD3
T8865	665-667	Protein	denotes	28
T8866	722-727	Protein	denotes	TGF-β
T8867	833-838	Protein	denotes	Foxp3
T8868	843-848	Protein	denotes	IFN-γ
T8869	849-859	Gene_expression	denotes	expression
T8870	861-866	Protein	denotes	TGF-β
T8871	867-874	Positive_regulation	denotes	induced
T8872	875-880	Protein	denotes	Foxp3
T8873	884-889	Protein	denotes	CbfbF
T8874	892-899	Protein	denotes	CD4-cre
T8875	961-968	Negative_regulation	denotes	reduced
T8876	972-977	Protein	denotes	CbfbF
T8877	980-987	Protein	denotes	CD4-cre
T8878	1009-1017	Positive_regulation	denotes	enhanced
T8879	1018-1023	Protein	denotes	Foxp3
T8880	1024-1034	Gene_expression	denotes	expression
T8881	1055-1060	Protein	denotes	TGF-β
T8882	1086-1089	Protein	denotes	CD4
T8883	1104-1109	Protein	denotes	CbfbF
T8884	1112-1119	Protein	denotes	CD4-cre
T8885	1132-1137	Protein	denotes	Foxp3
T8886	1160-1165	Protein	denotes	TGF-β
T8887	1177-1186	Positive_regulation	denotes	induction
T8888	1190-1195	Protein	denotes	Foxp3
T8889	1229-1234	Protein	denotes	CbfbF
T8890	1237-1244	Protein	denotes	CD4-cre
T8891	1245-1248	Protein	denotes	CD4
T8892	1316-1326	Negative_regulation	denotes	deficiency
T8893	1330-1334	Protein	denotes	Runx
T8894	1335-1342	Binding	denotes	binding
T8895	1350-1357	Regulation	denotes	affects
T8896	1362-1367	Protein	denotes	TGF-β
T8897	1368-1377	Positive_regulation	denotes	induction
T8898	1381-1386	Protein	denotes	Foxp3
T8899	1445-1454	Positive_regulation	denotes	induction
T8900	1458-1463	Protein	denotes	Foxp3
T8901	1480-1484	Protein	denotes	IL-4
T8902	1489-1494	Protein	denotes	IFN-γ
T8903	1500-1511	Negative_regulation	denotes	neutralized
T8904	2625-2629	Protein	denotes	RUNX
T8905	2688-2691	Protein	denotes	CD4
T8906	2741-2746	Protein	denotes	CbfbF
T8907	2752-2757	Protein	denotes	CbfbF
T8908	2760-2767	Protein	denotes	CD4-cre
T8909	2795-2800	Protein	denotes	Foxp3
T8910	2806-2809	Protein	denotes	GFP
T8911	2850-2854	Protein	denotes	Rag2
T8912	2876-2879	Protein	denotes	CD4
T8913	2983-2992	Protein	denotes	Foxp3-GFP
T8914	2993-3003	Gene_expression	denotes	expression
T8915	3061-3064	Protein	denotes	CD4
T8916	3093-3098	Protein	denotes	Foxp3
T8917	3099-3109	Gene_expression	denotes	expression
T8918	3183-3188	Protein	denotes	CbfbF
T8919	3191-3198	Protein	denotes	CD4-cre
T8920	3290-3294	Protein	denotes	RUNX
T8921	3334-3337	Protein	denotes	CD4
T8922	3339-3344	Protein	denotes	Foxp3
T31360	1557-1561	Protein	denotes	Cbfb
T31361	1562-1571	Negative_regulation	denotes	deficient		true
T31362	1572-1579	Protein	denotes	CD4-cre		true
T31363	1614-1619	Protein	denotes	Foxp3
T31364	1621-1624	Protein	denotes	CD4		true
T31365	1659-1662	Protein	denotes	CD4
T31366	1664-1667	Protein	denotes	CD8
T31367	1682-1687	Protein	denotes	CbfbF
T31368	1690-1697	Protein	denotes	CD4-cre
T31369	1710-1715	Protein	denotes	CbfbF
T31370	1718-1725	Protein	denotes	CD4-cre
T31371	1765-1768	Protein	denotes	CD3
T31372	1769-1771	Protein	denotes	28
T31373	1785-1789	Protein	denotes	IL-2
T31374	1852-1857	Protein	denotes	TGF-β
T31375	1967-1972	Protein	denotes	Foxp3
T31376	1977-1982	Protein	denotes	IFN-γ
T31377	1983-1993	Gene_expression	denotes	expression
T31378	2039-2042	Protein	denotes	CD4
T31379	2057-2061	Protein	denotes	Cbfb
T31380	2062-2069	Protein	denotes	CD4-cre
T31381	2099-2104	Protein	denotes	Foxp3
T31382	2110-2113	Protein	denotes	GFP
T31383	2155-2158	Protein	denotes	Rag
T31384	2159-2168	Negative_regulation	denotes	deficient
T31385	2216-2220	Protein	denotes	TCRβ
T31386	2221-2224	Protein	denotes	CD4
T31387	2343-2352	Protein	denotes	Foxp3-GFP
T31388	2353-2363	Gene_expression	denotes	expression
T31389	2390-2395	Protein	denotes	CbfbF
T31390	2398-2405	Protein	denotes	CD4-cre
T31391	2418-2423	Protein	denotes	CbfbF
T31392	2426-2433	Protein	denotes	CD4-cre
R7059	T8834	T8833	themeOf	Foxp3,induction
R7060	T8838	T8837	themeOf	binding,increases
R7061	T8842	T8841	themeOf	induction,involved
R7062	T8843	T8842	themeOf	Foxp3,induction
R7063	T8846	T8845	themeOf	CD4-cre,expression
R7064	T8847	T8848	causeOf	TGF-β,synergize
R7065	T8849	T8848	themeOf	induction,synergize
R7066	T8850	T8849	themeOf	Foxp3,induction
R7067	T8851	T8852	causeOf	Runx,mediated
R7068	T8852	T8855	themeOf	mediated,dependent
R7069	T8853	T8855	themeOf	induction,dependent
R7070	T8853	T8852	themeOf	induction,mediated
R7071	T8854	T8853	themeOf	Foxp3,induction
R7072	T8857	T8856	themeOf	CBFβ,expression
R7073	T8867	T8869	themeOf	Foxp3,expression
R7074	T8868	T8869	themeOf	IFN-γ,expression
R7075	T8870	T8871	causeOf	TGF-β,induced
R7076	T8871	T8875	themeOf	induced,reduced
R7077	T8872	T8871	themeOf	Foxp3,induced
R7078	T8879	T8880	themeOf	Foxp3,expression
R7079	T8880	T8878	themeOf	expression,enhanced
R7080	T8881	T8878	causeOf	TGF-β,enhanced
R7081	T8886	T8878	causeOf	TGF-β,enhanced
R7082	T8888	T8887	themeOf	Foxp3,induction
R7083	T8893	T8894	themeOf	Runx,binding
R7084	T8894	T8895	causeOf	binding,affects
R7085	T8896	T8897	causeOf	TGF-β,induction
R7086	T8897	T8895	themeOf	induction,affects
R7087	T8898	T8897	themeOf	Foxp3,induction
R7088	T8900	T8899	themeOf	Foxp3,induction
R7089	T8901	T8903	themeOf	IL-4,neutralized
R7090	T8902	T8903	themeOf	IFN-γ,neutralized
R7091	T8913	T8914	themeOf	Foxp3-GFP,expression
R7092	T8916	T8917	themeOf	Foxp3,expression
R24101	T31360	T31361	themeOf	Cbfb,deficient
R24102	T31375	T31377	themeOf	Foxp3,expression
R24103	T31376	T31377	themeOf	IFN-γ,expression
R24104	T31383	T31384	themeOf	Rag,deficient
R24105	T31387	T31388	themeOf	Foxp3-GFP,expression

PMC:2806624 / 18928-22282 JSONTXT

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