PMC:2806624 / 189-1532
Annnotations
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T238 | 0-8 | NN | denotes | Forkhead |
T239 | 9-12 | NN | denotes | box |
T240 | 13-15 | NN | denotes | P3 |
T241 | 16-17 | -LRB- | denotes | ( |
T242 | 17-22 | NN | denotes | FOXP3 |
T243 | 22-23 | -RRB- | denotes | ) |
T244 | 23-33 | CC | denotes | +CD4+CD25+ |
T245 | 34-43 | JJ | denotes | inducible |
T246 | 44-54 | JJ | denotes | regulatory |
T247 | 55-56 | NN | denotes | T |
T248 | 57-58 | -LRB- | denotes | ( |
T249 | 58-60 | NN | denotes | iT |
T250 | 61-64 | NN | denotes | reg |
T251 | 64-65 | -RRB- | denotes | ) |
T252 | 66-71 | NN | denotes | cells |
T253 | 72-76 | VB | denotes | play |
T254 | 77-79 | DT | denotes | an |
T255 | 80-89 | JJ | denotes | important |
T256 | 90-94 | NN | denotes | role |
T257 | 95-97 | IN | denotes | in |
T258 | 98-104 | JJ | denotes | immune |
T259 | 105-114 | NN | denotes | tolerance |
T260 | 115-118 | CC | denotes | and |
T261 | 119-130 | NN | denotes | homeostasis |
T262 | 132-134 | IN | denotes | In |
T263 | 135-139 | DT | denotes | this |
T264 | 140-145 | NN | denotes | study |
T265 | 145-146 | -COMMA- | denotes | , |
T266 | 147-149 | PRP | denotes | we |
T267 | 150-154 | VB | denotes | show |
T268 | 155-159 | IN | denotes | that |
T269 | 160-163 | DT | denotes | the |
T270 | 164-176 | VB | denotes | transforming |
T271 | 177-183 | NN | denotes | growth |
T272 | 184-192 | NN | denotes | factor-β |
T273 | 193-194 | -LRB- | denotes | ( |
T274 | 194-199 | NN | denotes | TGF-β |
T275 | 199-200 | -RRB- | denotes | ) |
T276 | 201-208 | VB | denotes | induces |
T277 | 209-212 | DT | denotes | the |
T278 | 213-223 | NN | denotes | expression |
T279 | 224-226 | IN | denotes | of |
T280 | 227-230 | DT | denotes | the |
T281 | 231-243 | JJ | denotes | Runt-related |
T282 | 244-257 | NN | denotes | transcription |
T283 | 258-265 | NN | denotes | factors |
T284 | 266-271 | NN | denotes | RUNX1 |
T285 | 272-275 | CC | denotes | and |
T286 | 276-281 | NN | denotes | RUNX3 |
T287 | 282-284 | IN | denotes | in |
T288 | 285-289 | JJ | denotes | CD4+ |
T289 | 290-291 | NN | denotes | T |
T290 | 292-297 | NN | denotes | cells |
T291 | 299-303 | DT | denotes | This |
T292 | 304-313 | NN | denotes | induction |
T293 | 314-319 | VB | denotes | seems |
T294 | 320-322 | TO | denotes | to |
T295 | 323-325 | VB | denotes | be |
T296 | 326-327 | DT | denotes | a |
T297 | 328-340 | NN | denotes | prerequisite |
T298 | 341-344 | IN | denotes | for |
T299 | 345-348 | DT | denotes | the |
T300 | 349-356 | NN | denotes | binding |
T301 | 357-359 | IN | denotes | of |
T302 | 360-365 | NN | denotes | RUNX1 |
T303 | 366-369 | CC | denotes | and |
T304 | 370-375 | NN | denotes | RUNX3 |
T305 | 376-378 | TO | denotes | to |
T306 | 379-384 | CD | denotes | three |
T307 | 385-393 | JJ | denotes | putative |
T308 | 394-398 | NN | denotes | RUNX |
T309 | 399-406 | NN | denotes | binding |
T310 | 407-412 | NN | denotes | sites |
T311 | 413-415 | IN | denotes | in |
T312 | 416-419 | DT | denotes | the |
T313 | 420-425 | NN | denotes | FOXP3 |
T314 | 426-434 | NN | denotes | promoter |
T315 | 436-448 | NN | denotes | Inactivation |
T316 | 449-451 | IN | denotes | of |
T317 | 452-455 | DT | denotes | the |
T318 | 456-460 | NN | denotes | gene |
T319 | 461-469 | VB | denotes | encoding |
T320 | 470-474 | NN | denotes | RUNX |
T321 | 475-483 | NN | denotes | cofactor |
T322 | 484-496 | JJ | denotes | core-binding |
T323 | 497-505 | NN | denotes | factor-β |
T324 | 506-507 | -LRB- | denotes | ( |
T325 | 507-511 | NN | denotes | CBFβ |
T326 | 511-512 | -RRB- | denotes | ) |
T327 | 513-515 | IN | denotes | in |
T328 | 516-520 | NN | denotes | mice |
T329 | 521-524 | CC | denotes | and |
T330 | 525-530 | JJ | denotes | small |
T331 | 531-542 | VB | denotes | interfering |
T332 | 543-546 | NN | denotes | RNA |
T333 | 547-548 | -LRB- | denotes | ( |
T334 | 548-553 | NN | denotes | siRNA |
T335 | 553-554 | -RRB- | denotes | ) |
T336 | 554-563 | JJ | denotes | -mediated |
T337 | 564-575 | NN | denotes | suppression |
T338 | 576-578 | IN | denotes | of |
T339 | 579-584 | NN | denotes | RUNX1 |
T340 | 585-588 | CC | denotes | and |
T341 | 589-594 | NN | denotes | RUNX3 |
T342 | 595-597 | IN | denotes | in |
T343 | 598-603 | JJ | denotes | human |
T344 | 604-605 | NN | denotes | T |
T345 | 606-611 | NN | denotes | cells |
T346 | 612-620 | VB | denotes | resulted |
T347 | 621-623 | IN | denotes | in |
T348 | 624-631 | VB | denotes | reduced |
T349 | 632-642 | NN | denotes | expression |
T350 | 643-645 | IN | denotes | of |
T351 | 646-651 | NN | denotes | Foxp3 |
T352 | 653-656 | DT | denotes | The |
T353 | 657-659 | FW | denotes | in |
T354 | 660-664 | FW | denotes | vivo |
T355 | 665-675 | NN | denotes | conversion |
T356 | 676-678 | IN | denotes | of |
T357 | 679-684 | JJ | denotes | naive |
T358 | 685-689 | JJ | denotes | CD4+ |
T359 | 690-691 | NN | denotes | T |
T360 | 692-697 | NN | denotes | cells |
T361 | 698-702 | IN | denotes | into |
T362 | 703-709 | JJ | denotes | Foxp3+ |
T363 | 710-712 | NN | denotes | iT |
T364 | 713-716 | NN | denotes | reg |
T365 | 717-722 | NN | denotes | cells |
T366 | 723-726 | VB | denotes | was |
T367 | 727-740 | RB | denotes | significantly |
T368 | 741-750 | VB | denotes | decreased |
T369 | 751-753 | IN | denotes | in |
T370 | 754-764 | RB | denotes | adoptively |
T371 | 765-776 | VB | denotes | transferred |
T372 | 777-784 | NN | denotes | CbfbF/F |
T373 | 785-792 | JJ | denotes | CD4-cre |
T374 | 793-798 | JJ | denotes | naive |
T375 | 799-800 | NN | denotes | T |
T376 | 801-806 | NN | denotes | cells |
T377 | 807-811 | IN | denotes | into |
T378 | 812-819 | NN | denotes | Rag2−/− |
T379 | 820-824 | NN | denotes | mice |
T380 | 826-830 | CC | denotes | Both |
T381 | 831-836 | NN | denotes | RUNX1 |
T382 | 837-840 | CC | denotes | and |
T383 | 841-846 | NN | denotes | RUNX3 |
T384 | 847-852 | NN | denotes | siRNA |
T385 | 853-861 | JJ | denotes | silenced |
T386 | 862-867 | JJ | denotes | human |
T387 | 868-869 | NN | denotes | T |
T388 | 870-873 | NN | denotes | reg |
T389 | 874-879 | NN | denotes | cells |
T390 | 880-883 | CC | denotes | and |
T391 | 884-891 | NN | denotes | CbfbF/F |
T392 | 892-899 | JJ | denotes | CD4-cre |
T393 | 900-905 | NN | denotes | mouse |
T394 | 906-907 | NN | denotes | T |
T395 | 908-911 | NN | denotes | reg |
T396 | 912-917 | NN | denotes | cells |
T397 | 918-924 | VB | denotes | showed |
T398 | 925-935 | VB | denotes | diminished |
T399 | 936-947 | JJ | denotes | suppressive |
T400 | 948-956 | NN | denotes | function |
T401 | 957-959 | FW | denotes | in |
T402 | 960-965 | FW | denotes | vitro |
T403 | 967-978 | VB | denotes | Circulating |
T404 | 979-984 | JJ | denotes | human |
T405 | 985-989 | JJ | denotes | CD4+ |
T406 | 990-998 | NN | denotes | CD25high |
T407 | 999-1005 | NN | denotes | CD127− |
T408 | 1006-1007 | NN | denotes | T |
T409 | 1008-1011 | NN | denotes | reg |
T410 | 1012-1017 | NN | denotes | cells |
T411 | 1018-1031 | RB | denotes | significantly |
T412 | 1032-1041 | VB | denotes | expressed |
T413 | 1042-1048 | JJ | denotes | higher |
T414 | 1049-1055 | NN | denotes | levels |
T415 | 1056-1058 | IN | denotes | of |
T416 | 1059-1064 | NN | denotes | RUNX3 |
T417 | 1064-1065 | -COMMA- | denotes | , |
T418 | 1066-1071 | NN | denotes | FOXP3 |
T419 | 1071-1072 | -COMMA- | denotes | , |
T420 | 1073-1076 | CC | denotes | and |
T421 | 1077-1082 | NN | denotes | TGF-β |
T422 | 1083-1087 | NN | denotes | mRNA |
T423 | 1088-1096 | VB | denotes | compared |
T424 | 1097-1101 | IN | denotes | with |
T425 | 1102-1111 | NN | denotes | CD4+CD25− |
T426 | 1112-1117 | NN | denotes | cells |
T427 | 1119-1130 | RB | denotes | Furthermore |
T428 | 1130-1131 | -COMMA- | denotes | , |
T429 | 1132-1137 | NN | denotes | FOXP3 |
T430 | 1138-1141 | CC | denotes | and |
T431 | 1142-1147 | NN | denotes | RUNX3 |
T432 | 1148-1152 | VB | denotes | were |
T433 | 1153-1164 | VB | denotes | colocalized |
T434 | 1165-1167 | IN | denotes | in |
T435 | 1168-1173 | JJ | denotes | human |
T436 | 1174-1180 | NN | denotes | tonsil |
T437 | 1181-1182 | NN | denotes | T |
T438 | 1183-1186 | NN | denotes | reg |
T439 | 1187-1192 | NN | denotes | cells |
T440 | 1194-1199 | DT | denotes | These |
T441 | 1200-1204 | NN | denotes | data |
T442 | 1205-1216 | VB | denotes | demonstrate |
T443 | 1217-1221 | NN | denotes | Runx |
T444 | 1222-1235 | NN | denotes | transcription |
T445 | 1236-1243 | NN | denotes | factors |
T446 | 1244-1246 | IN | denotes | as |
T447 | 1247-1248 | DT | denotes | a |
T448 | 1249-1258 | JJ | denotes | molecular |
T449 | 1259-1263 | NN | denotes | link |
T450 | 1264-1266 | IN | denotes | in |
T451 | 1267-1280 | JJ | denotes | TGF-β–induced |
T452 | 1281-1286 | NN | denotes | Foxp3 |
T453 | 1287-1297 | NN | denotes | expression |
T454 | 1298-1300 | IN | denotes | in |
T455 | 1301-1303 | NN | denotes | iT |
T456 | 1304-1307 | NN | denotes | reg |
T457 | 1308-1312 | NN | denotes | cell |
T458 | 1313-1328 | NN | denotes | differentiation |
T459 | 1329-1332 | CC | denotes | and |
T460 | 1333-1341 | NN | denotes | function |
R98 | T240 | T238 | arg1Of | P3,Forkhead |
R99 | T240 | T239 | arg1Of | P3,box |
R100 | T240 | T241 | arg1Of | P3,( |
R101 | T240 | T244 | arg1Of | P3,+CD4+CD25+ |
R102 | T242 | T241 | arg2Of | FOXP3,( |
R103 | T243 | T241 | arg3Of | ),( |
R104 | T244 | T253 | arg1Of | +CD4+CD25+,play |
R105 | T249 | T248 | arg2Of | iT,( |
R106 | T249 | T250 | arg1Of | iT,reg |
R107 | T251 | T248 | arg3Of | ),( |
R108 | T252 | T244 | arg2Of | cells,+CD4+CD25+ |
R109 | T252 | T245 | arg1Of | cells,inducible |
R110 | T252 | T246 | arg1Of | cells,regulatory |
R111 | T252 | T247 | arg1Of | cells,T |
R112 | T252 | T248 | arg1Of | cells,( |
R113 | T253 | T257 | arg1Of | play,in |
R114 | T256 | T253 | arg2Of | role,play |
R115 | T256 | T254 | arg1Of | role,an |
R116 | T256 | T255 | arg1Of | role,important |
R117 | T259 | T260 | arg1Of | tolerance,and |
R118 | T260 | T257 | arg2Of | and,in |
R119 | T260 | T258 | arg1Of | and,immune |
R120 | T261 | T260 | arg2Of | homeostasis,and |
R121 | T264 | T262 | arg2Of | study,In |
R122 | T264 | T263 | arg1Of | study,this |
R123 | T266 | T267 | arg1Of | we,show |
R124 | T267 | T262 | arg1Of | show,In |
R125 | T267 | T265 | arg1Of | show,"," |
R126 | T272 | T269 | arg1Of | factor-β,the |
R127 | T272 | T270 | arg1Of | factor-β,transforming |
R128 | T272 | T271 | arg1Of | factor-β,growth |
R129 | T272 | T273 | arg1Of | factor-β,( |
R130 | T272 | T276 | arg1Of | factor-β,induces |
R131 | T274 | T273 | arg2Of | TGF-β,( |
R132 | T275 | T273 | arg3Of | ),( |
R133 | T276 | T267 | arg2Of | induces,show |
R134 | T276 | T268 | arg1Of | induces,that |
R135 | T278 | T276 | arg2Of | expression,induces |
R136 | T278 | T277 | arg1Of | expression,the |
R137 | T278 | T279 | arg1Of | expression,of |
R138 | T278 | T287 | arg1Of | expression,in |
R139 | T283 | T281 | arg1Of | factors,Runt-related |
R140 | T283 | T282 | arg1Of | factors,transcription |
R141 | T284 | T285 | arg1Of | RUNX1,and |
R142 | T285 | T279 | arg2Of | and,of |
R143 | T285 | T280 | arg1Of | and,the |
R144 | T285 | T283 | arg1Of | and,factors |
R145 | T286 | T285 | arg2Of | RUNX3,and |
R146 | T290 | T287 | arg2Of | cells,in |
R147 | T290 | T288 | arg1Of | cells,CD4+ |
R148 | T290 | T289 | arg1Of | cells,T |
R149 | T292 | T291 | arg1Of | induction,This |
R150 | T292 | T293 | arg1Of | induction,seems |
R151 | T292 | T295 | arg1Of | induction,be |
R152 | T295 | T293 | arg2Of | be,seems |
R153 | T295 | T294 | arg1Of | be,to |
R154 | T297 | T295 | arg2Of | prerequisite,be |
R155 | T297 | T296 | arg1Of | prerequisite,a |
R156 | T297 | T298 | arg1Of | prerequisite,for |
R157 | T300 | T298 | arg2Of | binding,for |
R158 | T300 | T299 | arg1Of | binding,the |
R159 | T300 | T301 | arg1Of | binding,of |
R160 | T300 | T305 | arg1Of | binding,to |
R161 | T302 | T303 | arg1Of | RUNX1,and |
R162 | T303 | T301 | arg2Of | and,of |
R163 | T304 | T303 | arg2Of | RUNX3,and |
R164 | T310 | T305 | arg2Of | sites,to |
R165 | T310 | T306 | arg1Of | sites,three |
R166 | T310 | T307 | arg1Of | sites,putative |
R167 | T310 | T308 | arg1Of | sites,RUNX |
R168 | T310 | T309 | arg1Of | sites,binding |
R169 | T310 | T311 | arg1Of | sites,in |
R170 | T314 | T311 | arg2Of | promoter,in |
R171 | T314 | T312 | arg1Of | promoter,the |
R172 | T314 | T313 | arg1Of | promoter,FOXP3 |
R173 | T315 | T316 | arg1Of | Inactivation,of |
R174 | T315 | T327 | arg1Of | Inactivation,in |
R175 | T318 | T316 | arg2Of | gene,of |
R176 | T318 | T317 | arg1Of | gene,the |
R177 | T318 | T319 | arg1Of | gene,encoding |
R178 | T323 | T319 | arg2Of | factor-β,encoding |
R179 | T323 | T320 | arg1Of | factor-β,RUNX |
R180 | T323 | T321 | arg1Of | factor-β,cofactor |
R181 | T323 | T322 | arg1Of | factor-β,core-binding |
R182 | T323 | T324 | arg1Of | factor-β,( |
R183 | T325 | T324 | arg2Of | CBFβ,( |
R184 | T326 | T324 | arg3Of | ),( |
R185 | T328 | T329 | arg1Of | mice,and |
R186 | T329 | T327 | arg2Of | and,in |
R187 | T332 | T329 | arg2Of | RNA,and |
R188 | T332 | T330 | arg1Of | RNA,small |
R189 | T332 | T331 | arg1Of | RNA,interfering |
R190 | T332 | T333 | arg1Of | RNA,( |
R191 | T334 | T333 | arg2Of | siRNA,( |
R192 | T335 | T333 | arg3Of | ),( |
R193 | T337 | T315 | arg1Of | suppression,Inactivation |
R194 | T337 | T336 | arg1Of | suppression,-mediated |
R195 | T337 | T338 | arg1Of | suppression,of |
R196 | T337 | T346 | arg1Of | suppression,resulted |
R197 | T339 | T340 | arg1Of | RUNX1,and |
R198 | T340 | T338 | arg2Of | and,of |
R199 | T340 | T342 | arg1Of | and,in |
R200 | T341 | T340 | arg2Of | RUNX3,and |
R201 | T345 | T342 | arg2Of | cells,in |
R202 | T345 | T343 | arg1Of | cells,human |
R203 | T345 | T344 | arg1Of | cells,T |
R204 | T346 | T347 | arg1Of | resulted,in |
R205 | T349 | T347 | arg2Of | expression,in |
R206 | T349 | T348 | arg2Of | expression,reduced |
R207 | T349 | T350 | arg1Of | expression,of |
R208 | T351 | T350 | arg2Of | Foxp3,of |
R209 | T354 | T353 | arg1Of | vivo,in |
R210 | T355 | T352 | arg1Of | conversion,The |
R211 | T355 | T354 | arg1Of | conversion,vivo |
R212 | T355 | T356 | arg1Of | conversion,of |
R213 | T355 | T361 | arg1Of | conversion,into |
R214 | T355 | T366 | arg1Of | conversion,was |
R215 | T355 | T368 | arg2Of | conversion,decreased |
R216 | T360 | T356 | arg2Of | cells,of |
R217 | T360 | T357 | arg1Of | cells,naive |
R218 | T360 | T358 | arg1Of | cells,CD4+ |
R219 | T360 | T359 | arg1Of | cells,T |
R220 | T365 | T361 | arg2Of | cells,into |
R221 | T365 | T362 | arg1Of | cells,Foxp3+ |
R222 | T365 | T363 | arg1Of | cells,iT |
R223 | T365 | T364 | arg1Of | cells,reg |
R224 | T368 | T366 | arg2Of | decreased,was |
R225 | T368 | T367 | arg1Of | decreased,significantly |
R226 | T368 | T369 | arg1Of | decreased,in |
R227 | T368 | T377 | arg1Of | decreased,into |
R228 | T376 | T369 | arg2Of | cells,in |
R229 | T376 | T370 | arg1Of | cells,adoptively |
R230 | T376 | T371 | arg2Of | cells,transferred |
R231 | T376 | T372 | arg1Of | cells,CbfbF/F |
R232 | T376 | T373 | arg1Of | cells,CD4-cre |
R233 | T376 | T374 | arg1Of | cells,naive |
R234 | T376 | T375 | arg1Of | cells,T |
R235 | T379 | T377 | arg2Of | mice,into |
R236 | T379 | T378 | arg1Of | mice,Rag2−/− |
R237 | T381 | T382 | arg1Of | RUNX1,and |
R238 | T382 | T380 | arg1Of | and,Both |
R239 | T383 | T382 | arg2Of | RUNX3,and |
R240 | T389 | T384 | arg1Of | cells,siRNA |
R241 | T389 | T385 | arg1Of | cells,silenced |
R242 | T389 | T386 | arg1Of | cells,human |
R243 | T389 | T387 | arg1Of | cells,T |
R244 | T389 | T388 | arg1Of | cells,reg |
R245 | T389 | T390 | arg1Of | cells,and |
R246 | T390 | T381 | arg1Of | and,RUNX1 |
R247 | T390 | T383 | arg1Of | and,RUNX3 |
R248 | T390 | T397 | arg1Of | and,showed |
R249 | T396 | T390 | arg2Of | cells,and |
R250 | T396 | T391 | arg1Of | cells,CbfbF/F |
R251 | T396 | T392 | arg1Of | cells,CD4-cre |
R252 | T396 | T393 | arg1Of | cells,mouse |
R253 | T396 | T394 | arg1Of | cells,T |
R254 | T396 | T395 | arg1Of | cells,reg |
R255 | T397 | T402 | arg1Of | showed,vitro |
R256 | T400 | T397 | arg2Of | function,showed |
R257 | T400 | T398 | arg2Of | function,diminished |
R258 | T400 | T399 | arg1Of | function,suppressive |
R259 | T402 | T401 | arg1Of | vitro,in |
R260 | T410 | T403 | arg1Of | cells,Circulating |
R261 | T410 | T404 | arg1Of | cells,human |
R262 | T410 | T405 | arg1Of | cells,CD4+ |
R263 | T410 | T406 | arg1Of | cells,CD25high |
R264 | T410 | T407 | arg1Of | cells,CD127− |
R265 | T410 | T408 | arg1Of | cells,T |
R266 | T410 | T409 | arg1Of | cells,reg |
R267 | T410 | T412 | arg1Of | cells,expressed |
R268 | T412 | T411 | arg1Of | expressed,significantly |
R269 | T414 | T412 | arg2Of | levels,expressed |
R270 | T414 | T413 | arg1Of | levels,higher |
R271 | T414 | T415 | arg1Of | levels,of |
R272 | T416 | T417 | arg1Of | RUNX3,"," |
R273 | T417 | T420 | arg1Of | ",",and |
R274 | T418 | T417 | arg2Of | FOXP3,"," |
R275 | T420 | T415 | arg2Of | and,of |
R276 | T420 | T419 | arg1Of | and,"," |
R277 | T420 | T423 | arg1Of | and,compared |
R278 | T422 | T420 | arg2Of | mRNA,and |
R279 | T422 | T421 | arg1Of | mRNA,TGF-β |
R280 | T424 | T423 | arg2Of | with,compared |
R281 | T426 | T424 | arg2Of | cells,with |
R282 | T426 | T425 | arg1Of | cells,CD4+CD25− |
R283 | T429 | T430 | arg1Of | FOXP3,and |
R284 | T430 | T432 | arg1Of | and,were |
R285 | T430 | T433 | arg2Of | and,colocalized |
R286 | T431 | T430 | arg2Of | RUNX3,and |
R287 | T433 | T427 | arg1Of | colocalized,Furthermore |
R288 | T433 | T428 | arg1Of | colocalized,"," |
R289 | T433 | T432 | arg2Of | colocalized,were |
R290 | T433 | T434 | arg1Of | colocalized,in |
R291 | T439 | T434 | arg2Of | cells,in |
R292 | T439 | T435 | arg1Of | cells,human |
R293 | T439 | T436 | arg1Of | cells,tonsil |
R294 | T439 | T437 | arg1Of | cells,T |
R295 | T439 | T438 | arg1Of | cells,reg |
R296 | T441 | T440 | arg1Of | data,These |
R297 | T441 | T442 | arg1Of | data,demonstrate |
R298 | T442 | T446 | arg1Of | demonstrate,as |
R299 | T445 | T442 | arg2Of | factors,demonstrate |
R300 | T445 | T443 | arg1Of | factors,Runx |
R301 | T445 | T444 | arg1Of | factors,transcription |
R302 | T449 | T446 | arg2Of | link,as |
R303 | T449 | T447 | arg1Of | link,a |
R304 | T449 | T448 | arg1Of | link,molecular |
R305 | T449 | T450 | arg1Of | link,in |
R306 | T453 | T450 | arg2Of | expression,in |
R307 | T453 | T451 | arg1Of | expression,TGF-β–induced |
R308 | T453 | T452 | arg1Of | expression,Foxp3 |
R309 | T453 | T454 | arg1Of | expression,in |
R310 | T458 | T459 | arg1Of | differentiation,and |
R311 | T459 | T454 | arg2Of | and,in |
R312 | T459 | T455 | arg1Of | and,iT |
R313 | T459 | T456 | arg1Of | and,reg |
R314 | T459 | T457 | arg1Of | and,cell |
R315 | T460 | T459 | arg2Of | function,and |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T539 | 0-8 | NNP | denotes | Forkhead |
T540 | 9-12 | NN | denotes | box |
T541 | 13-15 | NN | denotes | P3 |
T542 | 16-17 | -LRB- | denotes | ( |
T543 | 17-22 | CD | denotes | FOXP3 |
T544 | 22-23 | -RRB- | denotes | ) |
T545 | 23-24 | FW | denotes | + |
T546 | 24-27 | FW | denotes | CD4 |
T547 | 27-28 | FW | denotes | + |
T548 | 28-32 | FW | denotes | CD25 |
T549 | 32-33 | FW | denotes | + |
T550 | 34-43 | FW | denotes | inducible |
T551 | 44-54 | JJ | denotes | regulatory |
T552 | 55-56 | NNP | denotes | T |
T553 | 57-58 | -LRB- | denotes | ( |
T554 | 58-60 | NNP | denotes | iT |
T555 | 61-64 | NN | denotes | reg |
T556 | 64-65 | -RRB- | denotes | ) |
T557 | 66-71 | NNS | denotes | cells |
T558 | 72-76 | VBP | denotes | play |
T559 | 77-79 | DT | denotes | an |
T560 | 80-89 | JJ | denotes | important |
T561 | 90-94 | NN | denotes | role |
T562 | 95-97 | IN | denotes | in |
T563 | 98-104 | JJ | denotes | immune |
T564 | 105-114 | NN | denotes | tolerance |
T565 | 115-118 | CC | denotes | and |
T566 | 119-130 | NN | denotes | homeostasis |
T567 | 130-131 | . | denotes | . |
T568 | 132-134 | IN | denotes | In |
T569 | 135-139 | DT | denotes | this |
T570 | 140-145 | NN | denotes | study |
T571 | 145-146 | , | denotes | , |
T572 | 147-149 | PRP | denotes | we |
T573 | 150-154 | VBP | denotes | show |
T574 | 155-159 | IN | denotes | that |
T575 | 160-163 | DT | denotes | the |
T576 | 164-176 | VBG | denotes | transforming |
T577 | 177-183 | NN | denotes | growth |
T578 | 184-192 | NN | denotes | factor-β |
T579 | 193-194 | -LRB- | denotes | ( |
T580 | 194-199 | NNP | denotes | TGF-β |
T581 | 199-200 | -RRB- | denotes | ) |
T582 | 201-208 | VBZ | denotes | induces |
T583 | 209-212 | DT | denotes | the |
T584 | 213-223 | NN | denotes | expression |
T585 | 224-226 | IN | denotes | of |
T586 | 227-230 | DT | denotes | the |
T587 | 231-243 | JJ | denotes | Runt-related |
T588 | 244-257 | NN | denotes | transcription |
T589 | 258-265 | NNS | denotes | factors |
T590 | 266-271 | NNP | denotes | RUNX1 |
T591 | 272-275 | CC | denotes | and |
T592 | 276-281 | NNP | denotes | RUNX3 |
T593 | 282-284 | IN | denotes | in |
T594 | 285-288 | NNP | denotes | CD4 |
T595 | 288-289 | NNP | denotes | + |
T596 | 290-291 | NNP | denotes | T |
T597 | 292-297 | NNS | denotes | cells |
T598 | 297-298 | . | denotes | . |
T599 | 299-303 | DT | denotes | This |
T600 | 304-313 | NN | denotes | induction |
T601 | 314-319 | VBZ | denotes | seems |
T602 | 320-322 | TO | denotes | to |
T603 | 323-325 | VB | denotes | be |
T604 | 326-327 | DT | denotes | a |
T605 | 328-340 | NN | denotes | prerequisite |
T606 | 341-344 | IN | denotes | for |
T607 | 345-348 | DT | denotes | the |
T608 | 349-356 | JJ | denotes | binding |
T609 | 357-359 | IN | denotes | of |
T610 | 360-365 | CD | denotes | RUNX1 |
T611 | 366-369 | CC | denotes | and |
T612 | 370-375 | CD | denotes | RUNX3 |
T613 | 376-378 | TO | denotes | to |
T614 | 379-384 | CD | denotes | three |
T615 | 385-393 | JJ | denotes | putative |
T616 | 394-398 | NNP | denotes | RUNX |
T617 | 399-406 | JJ | denotes | binding |
T618 | 407-412 | NNS | denotes | sites |
T619 | 413-415 | IN | denotes | in |
T620 | 416-419 | DT | denotes | the |
T621 | 420-425 | CD | denotes | FOXP3 |
T622 | 426-434 | NN | denotes | promoter |
T623 | 434-435 | . | denotes | . |
T624 | 436-448 | NN | denotes | Inactivation |
T625 | 449-451 | IN | denotes | of |
T626 | 452-455 | DT | denotes | the |
T627 | 456-460 | NN | denotes | gene |
T628 | 461-469 | VBG | denotes | encoding |
T629 | 470-474 | NNP | denotes | RUNX |
T630 | 475-483 | NN | denotes | cofactor |
T631 | 484-496 | JJ | denotes | core-binding |
T632 | 497-505 | NN | denotes | factor-β |
T633 | 506-507 | -LRB- | denotes | ( |
T634 | 507-511 | NNP | denotes | CBFβ |
T635 | 511-512 | -RRB- | denotes | ) |
T636 | 513-515 | IN | denotes | in |
T637 | 516-520 | NNS | denotes | mice |
T638 | 521-524 | CC | denotes | and |
T639 | 525-530 | JJ | denotes | small |
T640 | 531-542 | VBG | denotes | interfering |
T641 | 543-546 | NNP | denotes | RNA |
T642 | 547-548 | -LRB- | denotes | ( |
T643 | 548-553 | NNP | denotes | siRNA |
T644 | 553-554 | -RRB- | denotes | ) |
T645 | 554-555 | : | denotes | - |
T646 | 555-563 | VBN | denotes | mediated |
T647 | 564-575 | NN | denotes | suppression |
T648 | 576-578 | IN | denotes | of |
T649 | 579-584 | NNP | denotes | RUNX1 |
T650 | 585-588 | CC | denotes | and |
T651 | 589-594 | NNP | denotes | RUNX3 |
T652 | 595-597 | IN | denotes | in |
T653 | 598-603 | JJ | denotes | human |
T654 | 604-605 | NNP | denotes | T |
T655 | 606-611 | NNS | denotes | cells |
T656 | 612-620 | VBD | denotes | resulted |
T657 | 621-623 | IN | denotes | in |
T658 | 624-631 | VBN | denotes | reduced |
T659 | 632-642 | NN | denotes | expression |
T660 | 643-645 | IN | denotes | of |
T661 | 646-651 | NNP | denotes | Foxp3 |
T662 | 651-652 | . | denotes | . |
T663 | 653-656 | DT | denotes | The |
T664 | 657-659 | IN | denotes | in |
T665 | 660-664 | NN | denotes | vivo |
T666 | 665-675 | NN | denotes | conversion |
T667 | 676-678 | IN | denotes | of |
T668 | 679-684 | JJ | denotes | naive |
T669 | 685-688 | NNP | denotes | CD4 |
T670 | 688-689 | CD | denotes | + |
T671 | 690-691 | NNP | denotes | T |
T672 | 692-697 | NNS | denotes | cells |
T673 | 698-702 | IN | denotes | into |
T674 | 703-708 | JJ | denotes | Foxp3 |
T675 | 708-709 | NN | denotes | + |
T676 | 710-712 | NNP | denotes | iT |
T677 | 713-716 | NN | denotes | reg |
T678 | 717-722 | NNS | denotes | cells |
T679 | 723-726 | VBD | denotes | was |
T680 | 727-740 | RB | denotes | significantly |
T681 | 741-750 | VBN | denotes | decreased |
T682 | 751-753 | IN | denotes | in |
T683 | 754-764 | RB | denotes | adoptively |
T684 | 765-776 | VBN | denotes | transferred |
T685 | 777-784 | NNP | denotes | CbfbF/F |
T686 | 785-792 | NNP | denotes | CD4-cre |
T687 | 793-798 | JJ | denotes | naive |
T688 | 799-800 | NNP | denotes | T |
T689 | 801-806 | NNS | denotes | cells |
T690 | 807-811 | IN | denotes | into |
T691 | 812-816 | NNP | denotes | Rag2 |
T692 | 816-817 | NNP | denotes | − |
T693 | 817-818 | VBD | denotes | / |
T694 | 818-819 | CD | denotes | − |
T695 | 820-824 | NNS | denotes | mice |
T696 | 824-825 | . | denotes | . |
T697 | 826-830 | DT | denotes | Both |
T698 | 831-836 | NNP | denotes | RUNX1 |
T699 | 837-840 | CC | denotes | and |
T700 | 841-846 | NNP | denotes | RUNX3 |
T701 | 847-852 | NNP | denotes | siRNA |
T702 | 853-861 | VBD | denotes | silenced |
T703 | 862-867 | JJ | denotes | human |
T704 | 868-869 | NNP | denotes | T |
T705 | 870-873 | NN | denotes | reg |
T706 | 874-879 | NNS | denotes | cells |
T707 | 880-883 | CC | denotes | and |
T708 | 884-891 | NNP | denotes | CbfbF/F |
T709 | 892-899 | NNP | denotes | CD4-cre |
T710 | 900-905 | NN | denotes | mouse |
T711 | 906-907 | NNP | denotes | T |
T712 | 908-911 | NN | denotes | reg |
T713 | 912-917 | NNS | denotes | cells |
T714 | 918-924 | VBD | denotes | showed |
T715 | 925-935 | JJ | denotes | diminished |
T716 | 936-947 | JJ | denotes | suppressive |
T717 | 948-956 | NN | denotes | function |
T718 | 957-959 | IN | denotes | in |
T719 | 960-965 | NN | denotes | vitro |
T720 | 965-966 | . | denotes | . |
T721 | 967-978 | VBG | denotes | Circulating |
T722 | 979-984 | JJ | denotes | human |
T723 | 985-988 | NNP | denotes | CD4 |
T724 | 988-989 | NNP | denotes | + |
T725 | 990-998 | NNP | denotes | CD25high |
T726 | 999-1004 | NNP | denotes | CD127 |
T727 | 1004-1005 | VBD | denotes | − |
T728 | 1006-1007 | NNP | denotes | T |
T729 | 1008-1011 | NN | denotes | reg |
T730 | 1012-1017 | NNS | denotes | cells |
T731 | 1018-1031 | RB | denotes | significantly |
T732 | 1032-1041 | VBD | denotes | expressed |
T733 | 1042-1048 | JJR | denotes | higher |
T734 | 1049-1055 | NNS | denotes | levels |
T735 | 1056-1058 | IN | denotes | of |
T736 | 1059-1064 | NNP | denotes | RUNX3 |
T737 | 1064-1065 | , | denotes | , |
T738 | 1066-1071 | NNP | denotes | FOXP3 |
T739 | 1071-1072 | , | denotes | , |
T740 | 1073-1076 | CC | denotes | and |
T741 | 1077-1082 | NNP | denotes | TGF-β |
T742 | 1083-1087 | NNP | denotes | mRNA |
T743 | 1088-1096 | VBN | denotes | compared |
T744 | 1097-1101 | IN | denotes | with |
T745 | 1102-1105 | CD | denotes | CD4 |
T746 | 1105-1106 | CD | denotes | + |
T747 | 1106-1110 | NNS | denotes | CD25 |
T748 | 1110-1111 | VBP | denotes | − |
T749 | 1112-1117 | NNS | denotes | cells |
T750 | 1117-1118 | . | denotes | . |
T751 | 1119-1130 | RB | denotes | Furthermore |
T752 | 1130-1131 | , | denotes | , |
T753 | 1132-1137 | CD | denotes | FOXP3 |
T754 | 1138-1141 | CC | denotes | and |
T755 | 1142-1147 | CD | denotes | RUNX3 |
T756 | 1148-1152 | VBD | denotes | were |
T757 | 1153-1164 | VBN | denotes | colocalized |
T758 | 1165-1167 | IN | denotes | in |
T759 | 1168-1173 | JJ | denotes | human |
T760 | 1174-1180 | NN | denotes | tonsil |
T761 | 1181-1182 | NNP | denotes | T |
T762 | 1183-1186 | NN | denotes | reg |
T763 | 1187-1192 | NNS | denotes | cells |
T764 | 1192-1193 | . | denotes | . |
T765 | 1194-1199 | DT | denotes | These |
T766 | 1200-1204 | NNS | denotes | data |
T767 | 1205-1216 | VBP | denotes | demonstrate |
T768 | 1217-1221 | NNP | denotes | Runx |
T769 | 1222-1235 | NN | denotes | transcription |
T770 | 1236-1243 | NNS | denotes | factors |
T771 | 1244-1246 | IN | denotes | as |
T772 | 1247-1248 | DT | denotes | a |
T773 | 1249-1258 | JJ | denotes | molecular |
T774 | 1259-1263 | NN | denotes | link |
T775 | 1264-1266 | IN | denotes | in |
T776 | 1267-1272 | NNP | denotes | TGF-β |
T777 | 1273-1280 | VBD | denotes | induced |
T778 | 1281-1286 | JJ | denotes | Foxp3 |
T779 | 1287-1297 | NN | denotes | expression |
T780 | 1298-1300 | IN | denotes | in |
T781 | 1301-1303 | NNP | denotes | iT |
T782 | 1304-1307 | NN | denotes | reg |
T783 | 1308-1312 | NN | denotes | cell |
T784 | 1313-1328 | NN | denotes | differentiation |
T785 | 1329-1332 | CC | denotes | and |
T786 | 1333-1341 | NN | denotes | function |
T787 | 1341-1342 | . | denotes | . |
R334 | T539 | T541 | nmod | Forkhead,P3 |
R335 | T540 | T541 | compound | box,P3 |
R337 | T542 | T541 | punct | (,P3 |
R338 | T543 | T541 | appos | FOXP3,P3 |
R339 | T544 | T541 | punct | ),P3 |
R340 | T545 | T552 | nmod | +,T |
R341 | T546 | T552 | nmod | CD4,T |
R342 | T547 | T552 | nmod | +,T |
R343 | T548 | T552 | nmod | CD25,T |
R344 | T549 | T550 | nmod | +,inducible |
R345 | T550 | T552 | nmod | inducible,T |
R346 | T551 | T552 | amod | regulatory,T |
R347 | T552 | T557 | nmod | T,cells |
R348 | T553 | T555 | punct | (,reg |
R349 | T554 | T555 | compound | iT,reg |
R350 | T555 | T552 | appos | reg,T |
R351 | T556 | T557 | punct | ),cells |
R352 | T557 | T558 | nsubj | cells,play |
R353 | T558 | T558 | ROOT | play,play |
R354 | T559 | T561 | det | an,role |
R355 | T560 | T561 | amod | important,role |
R356 | T561 | T558 | dobj | role,play |
R357 | T562 | T558 | prep | in,play |
R358 | T563 | T564 | amod | immune,tolerance |
R359 | T564 | T562 | pobj | tolerance,in |
R360 | T565 | T564 | cc | and,tolerance |
R361 | T566 | T564 | conj | homeostasis,tolerance |
R362 | T567 | T558 | punct | .,play |
R363 | T568 | T573 | prep | In,show |
R364 | T569 | T570 | det | this,study |
R365 | T570 | T568 | pobj | study,In |
R366 | T571 | T573 | punct | ",",show |
R367 | T572 | T573 | nsubj | we,show |
R368 | T573 | T573 | ROOT | show,show |
R369 | T574 | T582 | mark | that,induces |
R370 | T575 | T578 | det | the,factor-β |
R371 | T576 | T578 | amod | transforming,factor-β |
R372 | T577 | T578 | compound | growth,factor-β |
R373 | T578 | T582 | nsubj | factor-β,induces |
R374 | T579 | T580 | punct | (,TGF-β |
R375 | T580 | T578 | appos | TGF-β,factor-β |
R376 | T581 | T578 | punct | ),factor-β |
R377 | T582 | T573 | ccomp | induces,show |
R378 | T583 | T584 | det | the,expression |
R379 | T584 | T582 | dobj | expression,induces |
R380 | T585 | T584 | prep | of,expression |
R381 | T586 | T589 | det | the,factors |
R382 | T587 | T589 | amod | Runt-related,factors |
R383 | T588 | T589 | compound | transcription,factors |
R384 | T589 | T585 | pobj | factors,of |
R385 | T590 | T597 | nmod | RUNX1,cells |
R386 | T591 | T590 | cc | and,RUNX1 |
R387 | T592 | T590 | conj | RUNX3,RUNX1 |
R388 | T593 | T590 | prep | in,RUNX1 |
R389 | T594 | T593 | pobj | CD4,in |
R390 | T595 | T597 | compound | +,cells |
R391 | T596 | T597 | compound | T,cells |
R392 | T597 | T584 | conj | cells,expression |
R393 | T598 | T573 | punct | .,show |
R394 | T599 | T600 | det | This,induction |
R395 | T600 | T601 | nsubj | induction,seems |
R396 | T601 | T601 | ROOT | seems,seems |
R397 | T602 | T603 | aux | to,be |
R398 | T603 | T601 | xcomp | be,seems |
R399 | T604 | T605 | det | a,prerequisite |
R400 | T605 | T603 | attr | prerequisite,be |
R401 | T606 | T605 | prep | for,prerequisite |
R402 | T607 | T608 | det | the,binding |
R403 | T608 | T606 | pobj | binding,for |
R404 | T609 | T608 | prep | of,binding |
R405 | T610 | T618 | nummod | RUNX1,sites |
R406 | T611 | T610 | cc | and,RUNX1 |
R407 | T612 | T614 | nummod | RUNX3,three |
R408 | T613 | T614 | nmod | to,three |
R409 | T614 | T610 | conj | three,RUNX1 |
R410 | T615 | T618 | amod | putative,sites |
R411 | T616 | T618 | nmod | RUNX,sites |
R412 | T617 | T618 | amod | binding,sites |
R413 | T618 | T609 | pobj | sites,of |
R414 | T619 | T618 | prep | in,sites |
R415 | T620 | T622 | det | the,promoter |
R416 | T621 | T622 | nummod | FOXP3,promoter |
R417 | T622 | T619 | pobj | promoter,in |
R418 | T623 | T601 | punct | .,seems |
R419 | T624 | T656 | nsubj | Inactivation,resulted |
R420 | T625 | T624 | prep | of,Inactivation |
R421 | T626 | T627 | det | the,gene |
R422 | T627 | T625 | pobj | gene,of |
R423 | T628 | T632 | amod | encoding,factor-β |
R424 | T629 | T632 | nmod | RUNX,factor-β |
R425 | T630 | T632 | nmod | cofactor,factor-β |
R426 | T631 | T632 | amod | core-binding,factor-β |
R427 | T632 | T624 | appos | factor-β,Inactivation |
R428 | T633 | T634 | punct | (,CBFβ |
R429 | T634 | T632 | appos | CBFβ,factor-β |
R430 | T635 | T634 | punct | ),CBFβ |
R431 | T636 | T632 | prep | in,factor-β |
R432 | T637 | T636 | pobj | mice,in |
R433 | T638 | T637 | cc | and,mice |
R434 | T639 | T641 | amod | small,RNA |
R435 | T640 | T641 | amod | interfering,RNA |
R436 | T641 | T637 | conj | RNA,mice |
R437 | T642 | T643 | punct | (,siRNA |
R438 | T643 | T641 | appos | siRNA,RNA |
R439 | T644 | T643 | punct | ),siRNA |
R440 | T645 | T646 | punct | -,mediated |
R441 | T646 | T647 | amod | mediated,suppression |
R442 | T647 | T632 | conj | suppression,factor-β |
R443 | T648 | T647 | prep | of,suppression |
R444 | T649 | T648 | pobj | RUNX1,of |
R445 | T650 | T649 | cc | and,RUNX1 |
R446 | T651 | T649 | conj | RUNX3,RUNX1 |
R447 | T652 | T647 | prep | in,suppression |
R448 | T653 | T655 | amod | human,cells |
R449 | T654 | T655 | compound | T,cells |
R450 | T655 | T652 | pobj | cells,in |
R451 | T656 | T656 | ROOT | resulted,resulted |
R452 | T657 | T656 | prep | in,resulted |
R453 | T658 | T659 | amod | reduced,expression |
R454 | T659 | T657 | pobj | expression,in |
R455 | T660 | T659 | prep | of,expression |
R456 | T661 | T660 | pobj | Foxp3,of |
R457 | T662 | T656 | punct | .,resulted |
R458 | T663 | T681 | nsubjpass | The,decreased |
R459 | T664 | T663 | prep | in,The |
R460 | T665 | T666 | compound | vivo,conversion |
R461 | T666 | T664 | pobj | conversion,in |
R462 | T667 | T666 | prep | of,conversion |
R463 | T668 | T672 | amod | naive,cells |
R464 | T669 | T672 | compound | CD4,cells |
R465 | T670 | T672 | nummod | +,cells |
R466 | T671 | T672 | compound | T,cells |
R467 | T672 | T667 | pobj | cells,of |
R468 | T673 | T666 | prep | into,conversion |
R469 | T674 | T678 | amod | Foxp3,cells |
R470 | T675 | T678 | compound | +,cells |
R471 | T676 | T677 | compound | iT,reg |
R472 | T677 | T678 | compound | reg,cells |
R473 | T678 | T673 | pobj | cells,into |
R474 | T679 | T681 | auxpass | was,decreased |
R475 | T680 | T681 | advmod | significantly,decreased |
R476 | T681 | T681 | ROOT | decreased,decreased |
R477 | T682 | T681 | prep | in,decreased |
R478 | T683 | T684 | advmod | adoptively,transferred |
R479 | T684 | T689 | amod | transferred,cells |
R480 | T685 | T686 | compound | CbfbF/F,CD4-cre |
R481 | T686 | T689 | amod | CD4-cre,cells |
R482 | T687 | T689 | amod | naive,cells |
R483 | T688 | T689 | compound | T,cells |
R484 | T689 | T682 | pobj | cells,in |
R485 | T690 | T681 | prep | into,decreased |
R486 | T691 | T692 | compound | Rag2,− |
R487 | T692 | T690 | pobj | −,into |
R488 | T693 | T681 | advcl | /,decreased |
R489 | T694 | T695 | nummod | −,mice |
R490 | T695 | T693 | dobj | mice,/ |
R491 | T696 | T681 | punct | .,decreased |
R492 | T697 | T698 | det | Both,RUNX1 |
R493 | T698 | T702 | nsubj | RUNX1,silenced |
R494 | T699 | T698 | cc | and,RUNX1 |
R495 | T700 | T701 | compound | RUNX3,siRNA |
R496 | T701 | T698 | conj | siRNA,RUNX1 |
R497 | T702 | T702 | ROOT | silenced,silenced |
R498 | T703 | T704 | amod | human,T |
R499 | T704 | T706 | compound | T,cells |
R500 | T705 | T706 | compound | reg,cells |
R501 | T706 | T702 | dobj | cells,silenced |
R502 | T707 | T706 | cc | and,cells |
R503 | T708 | T713 | compound | CbfbF/F,cells |
R504 | T709 | T713 | compound | CD4-cre,cells |
R505 | T710 | T711 | compound | mouse,T |
R506 | T711 | T713 | compound | T,cells |
R507 | T712 | T713 | compound | reg,cells |
R508 | T713 | T706 | conj | cells,cells |
R509 | T714 | T702 | conj | showed,silenced |
R510 | T715 | T717 | amod | diminished,function |
R511 | T716 | T717 | compound | suppressive,function |
R512 | T717 | T714 | dobj | function,showed |
R513 | T718 | T717 | prep | in,function |
R514 | T719 | T718 | pobj | vitro,in |
R515 | T720 | T714 | punct | .,showed |
R516 | T721 | T732 | nsubj | Circulating,expressed |
R517 | T722 | T726 | amod | human,CD127 |
R518 | T723 | T724 | compound | CD4,+ |
R519 | T724 | T726 | compound | +,CD127 |
R520 | T725 | T726 | compound | CD25high,CD127 |
R521 | T726 | T727 | nsubj | CD127,− |
R522 | T727 | T732 | dep | −,expressed |
R523 | T728 | T730 | compound | T,cells |
R524 | T729 | T730 | compound | reg,cells |
R525 | T730 | T727 | dobj | cells,− |
R526 | T731 | T732 | advmod | significantly,expressed |
R527 | T732 | T732 | ROOT | expressed,expressed |
R528 | T733 | T734 | amod | higher,levels |
R529 | T734 | T732 | dobj | levels,expressed |
R530 | T735 | T734 | prep | of,levels |
R531 | T736 | T735 | pobj | RUNX3,of |
R532 | T737 | T736 | punct | ",",RUNX3 |
R533 | T738 | T736 | conj | FOXP3,RUNX3 |
R534 | T739 | T738 | punct | ",",FOXP3 |
R535 | T740 | T738 | cc | and,FOXP3 |
R536 | T741 | T742 | compound | TGF-β,mRNA |
R537 | T742 | T738 | conj | mRNA,FOXP3 |
R538 | T743 | T732 | prep | compared,expressed |
R539 | T744 | T743 | prep | with,compared |
R540 | T745 | T748 | punct | CD4,− |
R541 | T746 | T747 | nummod | +,CD25 |
R542 | T747 | T748 | nsubj | CD25,− |
R543 | T748 | T749 | amod | −,cells |
R544 | T749 | T744 | pobj | cells,with |
R545 | T750 | T732 | punct | .,expressed |
R546 | T751 | T757 | advmod | Furthermore,colocalized |
R547 | T752 | T757 | punct | ",",colocalized |
R548 | T753 | T757 | nsubjpass | FOXP3,colocalized |
R549 | T754 | T753 | cc | and,FOXP3 |
R550 | T755 | T753 | conj | RUNX3,FOXP3 |
R551 | T756 | T757 | auxpass | were,colocalized |
R552 | T757 | T757 | ROOT | colocalized,colocalized |
R553 | T758 | T757 | prep | in,colocalized |
R554 | T759 | T760 | amod | human,tonsil |
R555 | T760 | T761 | compound | tonsil,T |
R556 | T761 | T763 | compound | T,cells |
R557 | T762 | T763 | compound | reg,cells |
R558 | T763 | T758 | pobj | cells,in |
R559 | T764 | T757 | punct | .,colocalized |
R560 | T765 | T766 | det | These,data |
R561 | T766 | T767 | nsubj | data,demonstrate |
R562 | T767 | T767 | ROOT | demonstrate,demonstrate |
R563 | T768 | T770 | amod | Runx,factors |
R564 | T769 | T770 | compound | transcription,factors |
R565 | T770 | T777 | nsubj | factors,induced |
R566 | T771 | T770 | prep | as,factors |
R567 | T772 | T774 | det | a,link |
R568 | T773 | T774 | amod | molecular,link |
R569 | T774 | T771 | pobj | link,as |
R570 | T775 | T774 | prep | in,link |
R571 | T776 | T775 | pobj | TGF-β,in |
R572 | T777 | T767 | ccomp | induced,demonstrate |
R573 | T778 | T779 | amod | Foxp3,expression |
R574 | T779 | T777 | dobj | expression,induced |
R575 | T780 | T777 | prep | in,induced |
R576 | T781 | T784 | compound | iT,differentiation |
R577 | T782 | T784 | compound | reg,differentiation |
R578 | T783 | T784 | compound | cell,differentiation |
R579 | T784 | T780 | pobj | differentiation,in |
R580 | T785 | T784 | cc | and,differentiation |
R581 | T786 | T784 | conj | function,differentiation |
R582 | T787 | T767 | punct | .,demonstrate |
UBERON-AE
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T137 | 1174-1180 | http://purl.obolibrary.org/obo/UBERON_0002372 | denotes | tonsil |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T789 | 244-257 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
T790 | 1222-1235 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
T791 | 119-130 | http://purl.obolibrary.org/obo/GO_0042592 | denotes | homeostasis |
T792 | 177-183 | http://purl.obolibrary.org/obo/GO_0040007 | denotes | growth |
T793 | 1308-1328 | http://purl.obolibrary.org/obo/GO_0030154 | denotes | cell differentiation |
GO-MF
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T868 | 177-192 | http://purl.obolibrary.org/obo/GO_0005160 | denotes | growth factor-β |
T869 | 349-356 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
T870 | 399-406 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
T871 | 489-496 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
GO-CC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T873 | 66-71 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T874 | 292-297 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T875 | 606-611 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T876 | 692-697 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T877 | 717-722 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T878 | 801-806 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T879 | 874-879 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T880 | 912-917 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T881 | 1012-1017 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T882 | 1112-1117 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T883 | 1187-1192 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T884 | 1308-1312 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T885 | 484-488 | http://purl.obolibrary.org/obo/GO_0019013 | denotes | core |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T139 | 0-131 | Sentence | denotes | Forkhead box P3 (FOXP3)+CD4+CD25+ inducible regulatory T (iT reg) cells play an important role in immune tolerance and homeostasis. |
T140 | 132-298 | Sentence | denotes | In this study, we show that the transforming growth factor-β (TGF-β) induces the expression of the Runt-related transcription factors RUNX1 and RUNX3 in CD4+ T cells. |
T141 | 299-435 | Sentence | denotes | This induction seems to be a prerequisite for the binding of RUNX1 and RUNX3 to three putative RUNX binding sites in the FOXP3 promoter. |
T142 | 436-652 | Sentence | denotes | Inactivation of the gene encoding RUNX cofactor core-binding factor-β (CBFβ) in mice and small interfering RNA (siRNA)-mediated suppression of RUNX1 and RUNX3 in human T cells resulted in reduced expression of Foxp3. |
T143 | 653-825 | Sentence | denotes | The in vivo conversion of naive CD4+ T cells into Foxp3+ iT reg cells was significantly decreased in adoptively transferred CbfbF/F CD4-cre naive T cells into Rag2−/− mice. |
T144 | 826-966 | Sentence | denotes | Both RUNX1 and RUNX3 siRNA silenced human T reg cells and CbfbF/F CD4-cre mouse T reg cells showed diminished suppressive function in vitro. |
T145 | 967-1118 | Sentence | denotes | Circulating human CD4+ CD25high CD127− T reg cells significantly expressed higher levels of RUNX3, FOXP3, and TGF-β mRNA compared with CD4+CD25− cells. |
T146 | 1119-1193 | Sentence | denotes | Furthermore, FOXP3 and RUNX3 were colocalized in human tonsil T reg cells. |
T147 | 1194-1342 | Sentence | denotes | These data demonstrate Runx transcription factors as a molecular link in TGF-β–induced Foxp3 expression in iT reg cell differentiation and function. |
T3 | 0-131 | Sentence | denotes | Forkhead box P3 (FOXP3)+CD4+CD25+ inducible regulatory T (iT reg) cells play an important role in immune tolerance and homeostasis. |
T4 | 132-298 | Sentence | denotes | In this study, we show that the transforming growth factor-β (TGF-β) induces the expression of the Runt-related transcription factors RUNX1 and RUNX3 in CD4+ T cells. |
T5 | 299-435 | Sentence | denotes | This induction seems to be a prerequisite for the binding of RUNX1 and RUNX3 to three putative RUNX binding sites in the FOXP3 promoter. |
T6 | 436-652 | Sentence | denotes | Inactivation of the gene encoding RUNX cofactor core-binding factor-β (CBFβ) in mice and small interfering RNA (siRNA)-mediated suppression of RUNX1 and RUNX3 in human T cells resulted in reduced expression of Foxp3. |
T7 | 653-825 | Sentence | denotes | The in vivo conversion of naive CD4+ T cells into Foxp3+ iT reg cells was significantly decreased in adoptively transferred CbfbF/F CD4-cre naive T cells into Rag2−/− mice. |
T8 | 826-966 | Sentence | denotes | Both RUNX1 and RUNX3 siRNA silenced human T reg cells and CbfbF/F CD4-cre mouse T reg cells showed diminished suppressive function in vitro. |
T9 | 967-1118 | Sentence | denotes | Circulating human CD4+ CD25high CD127− T reg cells significantly expressed higher levels of RUNX3, FOXP3, and TGF-β mRNA compared with CD4+CD25− cells. |
T10 | 1119-1193 | Sentence | denotes | Furthermore, FOXP3 and RUNX3 were colocalized in human tonsil T reg cells. |
T11 | 1194-1342 | Sentence | denotes | These data demonstrate Runx transcription factors as a molecular link in TGF-β–induced Foxp3 expression in iT reg cell differentiation and function. |
events-check-again
Id | Subject | Object | Predicate | Lexical cue | Speculation |
---|---|---|---|---|---|
T963 | 0-15 | Protein | denotes | Forkhead box P3 | |
T964 | 17-22 | Protein | denotes | FOXP3 | |
T965 | 24-27 | Protein | denotes | CD4 | |
T966 | 28-32 | Protein | denotes | CD25 | |
T967 | 164-192 | Protein | denotes | transforming growth factor-β | |
T968 | 194-199 | Protein | denotes | TGF-β | |
T969 | 201-208 | Positive_regulation | denotes | induces | |
T970 | 201-208 | Positive_regulation | denotes | induces | |
T971 | 213-223 | Gene_expression | denotes | expression | |
T972 | 213-223 | Gene_expression | denotes | expression | |
T973 | 266-271 | Protein | denotes | RUNX1 | |
T974 | 276-281 | Protein | denotes | RUNX3 | |
T975 | 285-288 | Protein | denotes | CD4 | |
T976 | 328-340 | Positive_regulation | denotes | prerequisite | true |
T977 | 328-340 | Positive_regulation | denotes | prerequisite | true |
T978 | 349-356 | Binding | denotes | binding | |
T979 | 349-356 | Binding | denotes | binding | |
T980 | 360-365 | Protein | denotes | RUNX1 | |
T981 | 370-375 | Protein | denotes | RUNX3 | |
T982 | 394-412 | Entity | denotes | RUNX binding sites | |
T983 | 420-425 | Protein | denotes | FOXP3 | |
T984 | 436-448 | Negative_regulation | denotes | Inactivation | |
T985 | 470-474 | Protein | denotes | RUNX | |
T986 | 484-505 | Protein | denotes | core-binding factor-β | |
T987 | 507-511 | Protein | denotes | CBFβ | |
T988 | 555-563 | Positive_regulation | denotes | mediated | |
T989 | 555-563 | Positive_regulation | denotes | mediated | |
T990 | 564-575 | Negative_regulation | denotes | suppression | |
T991 | 564-575 | Negative_regulation | denotes | suppression | |
T992 | 579-584 | Protein | denotes | RUNX1 | |
T993 | 589-594 | Protein | denotes | RUNX3 | |
T994 | 624-631 | Negative_regulation | denotes | reduced | |
T995 | 624-631 | Negative_regulation | denotes | reduced | |
T996 | 624-631 | Negative_regulation | denotes | reduced | |
T997 | 632-642 | Gene_expression | denotes | expression | |
T998 | 646-651 | Protein | denotes | Foxp3 | |
T999 | 685-688 | Protein | denotes | CD4 | |
T1000 | 703-708 | Protein | denotes | Foxp3 | |
T1001 | 777-781 | Protein | denotes | Cbfb | |
T1002 | 785-788 | Protein | denotes | CD4 | |
T1003 | 789-792 | Protein | denotes | cre | |
T1004 | 812-816 | Protein | denotes | Rag2 | |
T1005 | 831-836 | Protein | denotes | RUNX1 | |
T1006 | 841-846 | Protein | denotes | RUNX3 | |
T1007 | 847-852 | Negative_regulation | denotes | siRNA | |
T1008 | 847-852 | Negative_regulation | denotes | siRNA | |
T1009 | 884-888 | Protein | denotes | Cbfb | |
T1010 | 892-895 | Protein | denotes | CD4 | |
T1011 | 896-899 | Protein | denotes | cre | |
T1012 | 985-988 | Protein | denotes | CD4 | |
T1013 | 990-994 | Protein | denotes | CD25 | |
T1014 | 999-1004 | Protein | denotes | CD127 | |
T1015 | 1032-1041 | Transcription | denotes | expressed | |
T1016 | 1032-1041 | Transcription | denotes | expressed | |
T1017 | 1032-1041 | Transcription | denotes | expressed | |
T1018 | 1059-1064 | Protein | denotes | RUNX3 | |
T1019 | 1066-1071 | Protein | denotes | FOXP3 | |
T1020 | 1077-1082 | Protein | denotes | TGF-β | |
T1021 | 1102-1105 | Protein | denotes | CD4 | |
T1022 | 1106-1110 | Protein | denotes | CD25 | |
T1023 | 1132-1137 | Protein | denotes | FOXP3 | |
T1024 | 1142-1147 | Protein | denotes | RUNX3 | |
T1025 | 1153-1164 | Localization | denotes | colocalized | |
T1026 | 1153-1164 | Localization | denotes | colocalized | |
T1027 | 1181-1192 | Entity | denotes | T reg cells | |
T1028 | 1217-1221 | Protein | denotes | Runx | |
T1029 | 1259-1263 | Regulation | denotes | link | |
T1030 | 1267-1272 | Protein | denotes | TGF-β | |
T1031 | 1273-1280 | Positive_regulation | denotes | induced | |
T1032 | 1281-1286 | Protein | denotes | Foxp3 | |
T1033 | 1287-1297 | Gene_expression | denotes | expression | |
R667 | T964 | T963 | equivalentTo | FOXP3,Forkhead box P3 | |
R668 | T967 | T968 | equivalentTo | transforming growth factor-β,TGF-β | |
R669 | T968 | T969 | causeOf | TGF-β,induces | |
R670 | T968 | T970 | causeOf | TGF-β,induces | |
R671 | T971 | T969 | themeOf | expression,induces | |
R672 | T972 | T970 | themeOf | expression,induces | |
R673 | T973 | T971 | themeOf | RUNX1,expression | |
R674 | T974 | T972 | themeOf | RUNX3,expression | |
R675 | T978 | T976 | themeOf | binding,prerequisite | |
R676 | T979 | T977 | themeOf | binding,prerequisite | |
R677 | T980 | T978 | themeOf | RUNX1,binding | |
R678 | T981 | T979 | themeOf | RUNX3,binding | |
R679 | T982 | T978 | themeOf | RUNX binding sites,binding | |
R680 | T982 | T983 | partOf | RUNX binding sites,FOXP3 | |
R681 | T982 | T979 | themeOf | RUNX binding sites,binding | |
R682 | T984 | T994 | causeOf | Inactivation,reduced | |
R683 | T986 | T984 | themeOf | core-binding factor-β,Inactivation | |
R684 | T986 | T990 | themeOf | core-binding factor-β,suppression | |
R685 | T987 | T986 | equivalentTo | CBFβ,core-binding factor-β | |
R686 | T990 | T988 | themeOf | suppression,mediated | |
R687 | T990 | T995 | causeOf | suppression,reduced | |
R688 | T991 | T989 | themeOf | suppression,mediated | |
R689 | T991 | T996 | causeOf | suppression,reduced | |
R690 | T993 | T991 | themeOf | RUNX3,suppression | |
R691 | T997 | T994 | themeOf | expression,reduced | |
R692 | T997 | T995 | themeOf | expression,reduced | |
R693 | T997 | T996 | themeOf | expression,reduced | |
R694 | T998 | T997 | themeOf | Foxp3,expression | |
R695 | T1005 | T1007 | themeOf | RUNX1,siRNA | |
R696 | T1006 | T1008 | themeOf | RUNX3,siRNA | |
R697 | T1018 | T1015 | themeOf | RUNX3,expressed | |
R698 | T1019 | T1016 | themeOf | FOXP3,expressed | |
R699 | T1020 | T1017 | themeOf | TGF-β,expressed | |
R700 | T1023 | T1025 | themeOf | FOXP3,colocalized | |
R701 | T1024 | T1026 | themeOf | RUNX3,colocalized | |
R702 | T1027 | T1025 | locationOf | T reg cells,colocalized | |
R703 | T1027 | T1026 | locationOf | T reg cells,colocalized | |
R704 | T1028 | T1029 | causeOf | Runx,link | |
R705 | T1030 | T1031 | causeOf | TGF-β,induced | |
R706 | T1031 | T1029 | themeOf | induced,link | |
R707 | T1032 | T1033 | themeOf | Foxp3,expression | |
R708 | T1033 | T1031 | themeOf | expression,induced |
bionlp-st-ge-2016-reference
Id | Subject | Object | Predicate | Lexical cue | Speculation |
---|---|---|---|---|---|
T148 | 201-208 | Positive_regulation | denotes | induces | |
T149 | 555-563 | Positive_regulation | denotes | mediated | |
T150 | 564-575 | Negative_regulation | denotes | suppression | |
T151 | 555-563 | Positive_regulation | denotes | mediated | |
T152 | 564-575 | Negative_regulation | denotes | suppression | |
T153 | 624-631 | Negative_regulation | denotes | reduced | |
T154 | 632-642 | Gene_expression | denotes | expression | |
T155 | 624-631 | Negative_regulation | denotes | reduced | |
T156 | 624-631 | Negative_regulation | denotes | reduced | |
T157 | 847-852 | Negative_regulation | denotes | siRNA | |
T158 | 847-852 | Negative_regulation | denotes | siRNA | |
T159 | 213-223 | Gene_expression | denotes | expression | |
T160 | 1032-1041 | Transcription | denotes | expressed | |
T161 | 1032-1041 | Transcription | denotes | expressed | |
T162 | 1032-1041 | Transcription | denotes | expressed | |
T163 | 1153-1164 | Localization | denotes | colocalized | |
T164 | 1153-1164 | Localization | denotes | colocalized | |
T165 | 1259-1263 | Regulation | denotes | link | |
T166 | 1273-1280 | Positive_regulation | denotes | induced | |
T167 | 1287-1297 | Gene_expression | denotes | expression | |
T168 | 201-208 | Positive_regulation | denotes | induces | |
T169 | 213-223 | Gene_expression | denotes | expression | |
T170 | 328-340 | Positive_regulation | denotes | prerequisite | true |
T171 | 349-356 | Binding | denotes | binding | |
T172 | 328-340 | Positive_regulation | denotes | prerequisite | true |
T173 | 349-356 | Binding | denotes | binding | |
T174 | 436-448 | Negative_regulation | denotes | Inactivation | |
T176 | 266-271 | Protein | denotes | RUNX1 | |
T177 | 276-281 | Protein | denotes | RUNX3 | |
T178 | 285-288 | Protein | denotes | CD4 | |
T179 | 360-365 | Protein | denotes | RUNX1 | |
T205 | 1066-1071 | Protein | denotes | FOXP3 | |
T206 | 1077-1082 | Protein | denotes | TGF-β | |
T207 | 1102-1105 | Protein | denotes | CD4 | |
T208 | 0-15 | Protein | denotes | Forkhead box P3 | |
T209 | 1106-1110 | Protein | denotes | CD25 | |
T210 | 1132-1137 | Protein | denotes | FOXP3 | |
T211 | 1142-1147 | Protein | denotes | RUNX3 | |
T212 | 1217-1221 | Protein | denotes | Runx | |
T213 | 1281-1286 | Protein | denotes | Foxp3 | |
T214 | 17-22 | Protein | denotes | FOXP3 | |
T215 | 394-412 | Entity | denotes | RUNX binding sites | |
T216 | 1181-1192 | Entity | denotes | T reg cells | |
T217 | 24-27 | Protein | denotes | CD4 | |
T218 | 28-32 | Protein | denotes | CD25 | |
T219 | 164-192 | Protein | denotes | transforming growth factor-β | |
T220 | 194-199 | Protein | denotes | TGF-β | |
T221 | 1267-1272 | Protein | denotes | TGF-β | |
T180 | 370-375 | Protein | denotes | RUNX3 | |
T181 | 420-425 | Protein | denotes | FOXP3 | |
T182 | 470-474 | Protein | denotes | RUNX | |
T183 | 484-505 | Protein | denotes | core-binding factor-β | |
T184 | 507-511 | Protein | denotes | CBFβ | |
T185 | 579-584 | Protein | denotes | RUNX1 | |
T187 | 589-594 | Protein | denotes | RUNX3 | |
T188 | 646-651 | Protein | denotes | Foxp3 | |
T189 | 685-688 | Protein | denotes | CD4 | |
T190 | 703-708 | Protein | denotes | Foxp3 | |
T191 | 777-781 | Protein | denotes | Cbfb | |
T192 | 785-788 | Protein | denotes | CD4 | |
T193 | 789-792 | Protein | denotes | cre | |
T194 | 812-816 | Protein | denotes | Rag2 | |
T195 | 831-836 | Protein | denotes | RUNX1 | |
T196 | 841-846 | Protein | denotes | RUNX3 | |
T198 | 884-888 | Protein | denotes | Cbfb | |
T199 | 892-895 | Protein | denotes | CD4 | |
T200 | 896-899 | Protein | denotes | cre | |
T201 | 985-988 | Protein | denotes | CD4 | |
T202 | 990-994 | Protein | denotes | CD25 | |
T203 | 999-1004 | Protein | denotes | CD127 | |
T204 | 1059-1064 | Protein | denotes | RUNX3 | |
R50 | T150 | T149 | themeOf | suppression,mediated | |
R51 | T150 | T155 | causeOf | suppression,reduced | |
R52 | T152 | T151 | themeOf | suppression,mediated | |
R53 | T152 | T156 | causeOf | suppression,reduced | |
R54 | T154 | T153 | themeOf | expression,reduced | |
R55 | T154 | T155 | themeOf | expression,reduced | |
R56 | T154 | T156 | themeOf | expression,reduced | |
R57 | T159 | T148 | themeOf | expression,induces | |
R58 | T166 | T165 | themeOf | induced,link | |
R59 | T167 | T166 | themeOf | expression,induced | |
R60 | T169 | T168 | themeOf | expression,induces | |
R61 | T171 | T170 | themeOf | binding,prerequisite | |
R62 | T173 | T172 | themeOf | binding,prerequisite | |
R63 | T174 | T153 | causeOf | Inactivation,reduced | |
R64 | T176 | T159 | themeOf | RUNX1,expression | |
R65 | T177 | T169 | themeOf | RUNX3,expression | |
R66 | T179 | T171 | themeOf | RUNX1,binding | |
R67 | T205 | T161 | themeOf | FOXP3,expressed | |
R68 | T206 | T162 | themeOf | TGF-β,expressed | |
R69 | T210 | T163 | themeOf | FOXP3,colocalized | |
R70 | T211 | T164 | themeOf | RUNX3,colocalized | |
R71 | T212 | T165 | causeOf | Runx,link | |
R72 | T213 | T167 | themeOf | Foxp3,expression | |
R73 | T214 | T208 | equivalentTo | FOXP3,Forkhead box P3 | |
R74 | T215 | T171 | themeOf | RUNX binding sites,binding | |
R75 | T215 | T181 | partOf | RUNX binding sites,FOXP3 | |
R76 | T215 | T173 | themeOf | RUNX binding sites,binding | |
R77 | T216 | T163 | locationOf | T reg cells,colocalized | |
R78 | T216 | T164 | locationOf | T reg cells,colocalized | |
R79 | T219 | T220 | equivalentTo | transforming growth factor-β,TGF-β | |
R80 | T220 | T148 | causeOf | TGF-β,induces | |
R81 | T220 | T168 | causeOf | TGF-β,induces | |
R82 | T221 | T166 | causeOf | TGF-β,induced | |
R733 | T180 | T173 | themeOf | RUNX3,binding | |
R734 | T183 | T174 | themeOf | core-binding factor-β,Inactivation | |
R735 | T183 | T150 | themeOf | core-binding factor-β,suppression | |
R736 | T184 | T183 | equivalentTo | CBFβ,core-binding factor-β | |
R737 | T187 | T152 | themeOf | RUNX3,suppression | |
R738 | T188 | T154 | themeOf | Foxp3,expression | |
R739 | T195 | T157 | themeOf | RUNX1,siRNA | |
R740 | T196 | T158 | themeOf | RUNX3,siRNA | |
R741 | T204 | T160 | themeOf | RUNX3,expressed |
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T464 | 17-22 | Q9BZS1 | denotes | FOXP3 |
T465 | 24-27 | P01730 | denotes | CD4 |
T466 | 28-32 | P01589 | denotes | CD25 |
T467 | 164-192 | P01137 | denotes | transforming growth factor-β |
T468 | 194-199 | P01137 | denotes | TGF-β |
T469 | 231-265 | Q13761 | denotes | Runt-related transcription factors |
T470 | 231-265 | Q01196 | denotes | Runt-related transcription factors |
T471 | 231-265 | Q13950 | denotes | Runt-related transcription factors |
T472 | 266-271 | Q01196 | denotes | RUNX1 |
T473 | 276-281 | Q13761 | denotes | RUNX3 |
T474 | 285-288 | P01730 | denotes | CD4 |
T475 | 360-365 | Q01196 | denotes | RUNX1 |
T476 | 370-375 | Q13761 | denotes | RUNX3 |
T477 | 394-398 | Q01196 | denotes | RUNX |
T478 | 394-398 | Q13761 | denotes | RUNX |
T479 | 394-398 | Q13950 | denotes | RUNX |
T480 | 420-425 | Q9BZS1 | denotes | FOXP3 |
T481 | 470-474 | Q13950 | denotes | RUNX |
T482 | 470-474 | Q01196 | denotes | RUNX |
T483 | 470-474 | Q13761 | denotes | RUNX |
T484 | 507-511 | Q13951 | denotes | CBFβ |
T485 | 579-584 | Q01196 | denotes | RUNX1 |
T486 | 589-594 | Q13761 | denotes | RUNX3 |
T487 | 646-651 | Q9BZS1 | denotes | Foxp3 |
T488 | 685-688 | P01730 | denotes | CD4 |
T489 | 703-708 | Q9BZS1 | denotes | Foxp3 |
T490 | 785-788 | P01730 | denotes | CD4 |
T491 | 789-792 | P06956 | denotes | cre |
T492 | 812-816 | P55895 | denotes | Rag2 |
T493 | 831-836 | Q01196 | denotes | RUNX1 |
T494 | 841-846 | Q13761 | denotes | RUNX3 |
T495 | 892-895 | P01730 | denotes | CD4 |
T496 | 896-899 | P06956 | denotes | cre |
T497 | 985-988 | P01730 | denotes | CD4 |
T498 | 999-1004 | P16871 | denotes | CD127 |
T499 | 1059-1064 | Q13761 | denotes | RUNX3 |
T500 | 1066-1071 | Q9BZS1 | denotes | FOXP3 |
T501 | 1077-1082 | P01137 | denotes | TGF-β |
T502 | 1102-1105 | P01730 | denotes | CD4 |
T503 | 1106-1110 | P01589 | denotes | CD25 |
T504 | 1132-1137 | Q9BZS1 | denotes | FOXP3 |
T505 | 1142-1147 | Q13761 | denotes | RUNX3 |
T506 | 1217-1221 | Q13761 | denotes | Runx |
T507 | 1217-1221 | Q01196 | denotes | Runx |
T508 | 1217-1221 | Q13950 | denotes | Runx |
T509 | 1267-1272 | P01137 | denotes | TGF-β |
T510 | 1281-1286 | Q9BZS1 | denotes | Foxp3 |
test2
Id | Subject | Object | Predicate | Lexical cue | Speculation |
---|---|---|---|---|---|
T123 | 1032-1041 | Gene_expression | denotes | expressed | |
T124 | 1059-1064 | Protein | denotes | RUNX3 | |
T125 | 1066-1071 | Protein | denotes | FOXP3 | |
T126 | 1077-1082 | Protein | denotes | TGF-β | |
T127 | 1102-1105 | Protein | denotes | CD4 | |
T128 | 1106-1110 | Protein | denotes | CD25 | |
T129 | 1132-1137 | Protein | denotes | FOXP3 | |
T130 | 1142-1147 | Protein | denotes | RUNX3 | |
T131 | 1217-1221 | Protein | denotes | Runx | |
T132 | 1222-1235 | Transcription | denotes | transcription | |
T133 | 1267-1272 | Protein | denotes | TGF-β | |
T134 | 1273-1280 | Positive_regulation | denotes | induced | |
T135 | 1281-1286 | Protein | denotes | Foxp3 | |
T136 | 1287-1297 | Gene_expression | denotes | expression | |
T78 | 0-15 | Protein | denotes | Forkhead box P3 | |
T79 | 17-22 | Protein | denotes | FOXP3 | true |
T80 | 24-27 | Protein | denotes | CD4 | |
T81 | 28-32 | Protein | denotes | CD25 | true |
T82 | 164-192 | Protein | denotes | transforming growth factor-β | |
T83 | 194-199 | Protein | denotes | TGF-β | |
T84 | 201-208 | Positive_regulation | denotes | induces | |
T85 | 213-223 | Gene_expression | denotes | expression | |
T86 | 266-271 | Protein | denotes | RUNX1 | |
T87 | 276-281 | Protein | denotes | RUNX3 | |
T88 | 285-288 | Protein | denotes | CD4 | |
T89 | 328-340 | Positive_regulation | denotes | prerequisite | |
T90 | 349-356 | Binding | denotes | binding | |
T91 | 360-365 | Protein | denotes | RUNX1 | |
T92 | 370-375 | Protein | denotes | RUNX3 | |
T93 | 394-412 | Entity | denotes | RUNX binding sites | |
T94 | 420-425 | Protein | denotes | FOXP3 | |
T95 | 436-448 | Negative_regulation | denotes | Inactivation | |
T96 | 470-474 | Protein | denotes | RUNX | |
T97 | 484-505 | Protein | denotes | core-binding factor-β | |
T98 | 507-511 | Protein | denotes | CBFβ | |
T99 | 555-563 | Positive_regulation | denotes | mediated | |
T100 | 564-575 | Negative_regulation | denotes | suppression | |
T101 | 579-584 | Protein | denotes | RUNX1 | |
T102 | 589-594 | Protein | denotes | RUNX3 | |
T103 | 612-620 | Positive_regulation | denotes | resulted | |
T104 | 624-631 | Negative_regulation | denotes | reduced | |
T105 | 632-642 | Gene_expression | denotes | expression | |
T106 | 646-651 | Protein | denotes | Foxp3 | |
T107 | 685-688 | Protein | denotes | CD4 | |
T108 | 703-708 | Protein | denotes | Foxp3 | |
T109 | 741-750 | Negative_regulation | denotes | decreased | |
T110 | 777-782 | Protein | denotes | CbfbF | |
T111 | 785-788 | Protein | denotes | CD4 | |
T112 | 789-792 | Protein | denotes | cre | |
T113 | 812-816 | Protein | denotes | Rag2 | |
T114 | 831-836 | Protein | denotes | RUNX1 | |
T115 | 841-846 | Protein | denotes | RUNX3 | |
T116 | 847-852 | Negative_regulation | denotes | siRNA | |
T117 | 884-889 | Protein | denotes | CbfbF | |
T118 | 892-895 | Protein | denotes | CD4 | |
T119 | 896-899 | Protein | denotes | cre | |
T120 | 985-988 | Protein | denotes | CD4 | |
T121 | 990-998 | Protein | denotes | CD25high | |
T122 | 999-1004 | Protein | denotes | CD127 | |
R719 | T93 | T90 | themeOf | RUNX binding sites,binding | |
R720 | T93 | T94 | partOf | RUNX binding sites,FOXP3 | |
R721 | T95 | T103 | causeOf | Inactivation,resulted | |
R722 | T95 | T104 | causeOf | Inactivation,reduced | |
R723 | T97 | T95 | themeOf | core-binding factor-β,Inactivation | |
R724 | T98 | T97 | equivalentTo | CBFβ,core-binding factor-β | |
R725 | T100 | T99 | themeOf | suppression,mediated | |
R726 | T100 | T104 | causeOf | suppression,reduced | |
R727 | T101 | T100 | themeOf | RUNX1,suppression | |
R728 | T102 | T100 | themeOf | RUNX3,suppression | |
R729 | T105 | T104 | themeOf | expression,reduced | |
R730 | T106 | T105 | themeOf | Foxp3,expression | |
R731 | T114 | T116 | themeOf | RUNX1,siRNA | |
R732 | T115 | T116 | themeOf | RUNX3,siRNA | |
R48 | T135 | T136 | themeOf | Foxp3,expression | |
R49 | T136 | T134 | themeOf | expression,induced | |
R43 | T124 | T123 | themeOf | RUNX3,expressed | |
R44 | T125 | T123 | themeOf | FOXP3,expressed | |
R45 | T126 | T123 | themeOf | TGF-β,expressed | |
R46 | T131 | T132 | themeOf | Runx,transcription | |
R47 | T133 | T134 | causeOf | TGF-β,induced | |
R709 | T79 | T78 | equivalentTo | FOXP3,Forkhead box P3 | |
R710 | T82 | T83 | equivalentTo | transforming growth factor-β,TGF-β | |
R711 | T82 | T84 | causeOf | transforming growth factor-β,induces | |
R712 | T83 | T84 | causeOf | TGF-β,induces | |
R713 | T85 | T84 | themeOf | expression,induces | |
R714 | T86 | T85 | themeOf | RUNX1,expression | |
R715 | T87 | T85 | themeOf | RUNX3,expression | |
R716 | T90 | T89 | themeOf | binding,prerequisite | |
R717 | T91 | T90 | themeOf | RUNX1,binding | |
R718 | T92 | T90 | themeOf | RUNX3,binding |