PMC:2806624 / 0-419
Annnotations
pmc-enju-pas
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T222 | 0-13 | NN | denotes | Transcription |
| T223 | 14-21 | NN | denotes | factors |
| T224 | 22-27 | NN | denotes | RUNX1 |
| T225 | 28-31 | CC | denotes | and |
| T226 | 32-37 | NN | denotes | RUNX3 |
| T227 | 38-40 | IN | denotes | in |
| T228 | 41-44 | DT | denotes | the |
| T229 | 45-54 | NN | denotes | induction |
| T230 | 55-58 | CC | denotes | and |
| T231 | 59-70 | JJ | denotes | suppressive |
| T232 | 71-79 | NN | denotes | function |
| T233 | 80-82 | IN | denotes | of |
| T234 | 83-99 | JJ | denotes | Foxp3+ inducible |
| T235 | 100-110 | JJ | denotes | regulatory |
| T236 | 111-112 | NN | denotes | T |
| T237 | 113-118 | NN | denotes | cells |
| T238 | 189-197 | NN | denotes | Forkhead |
| T239 | 198-201 | NN | denotes | box |
| T240 | 202-204 | NN | denotes | P3 |
| T241 | 205-206 | -LRB- | denotes | ( |
| T242 | 206-211 | NN | denotes | FOXP3 |
| T243 | 211-212 | -RRB- | denotes | ) |
| T244 | 212-222 | CC | denotes | +CD4+CD25+ |
| T245 | 223-232 | JJ | denotes | inducible |
| T246 | 233-243 | JJ | denotes | regulatory |
| T247 | 244-245 | NN | denotes | T |
| T248 | 246-247 | -LRB- | denotes | ( |
| T249 | 247-249 | NN | denotes | iT |
| T250 | 250-253 | NN | denotes | reg |
| T251 | 253-254 | -RRB- | denotes | ) |
| T252 | 255-260 | NN | denotes | cells |
| T253 | 261-265 | VB | denotes | play |
| T254 | 266-268 | DT | denotes | an |
| T255 | 269-278 | JJ | denotes | important |
| T256 | 279-283 | NN | denotes | role |
| T257 | 284-286 | IN | denotes | in |
| T258 | 287-293 | JJ | denotes | immune |
| T259 | 294-303 | NN | denotes | tolerance |
| T260 | 304-307 | CC | denotes | and |
| T261 | 308-319 | NN | denotes | homeostasis |
| T262 | 321-323 | IN | denotes | In |
| T263 | 324-328 | DT | denotes | this |
| T264 | 329-334 | NN | denotes | study |
| T265 | 334-335 | -COMMA- | denotes | , |
| T266 | 336-338 | PRP | denotes | we |
| T267 | 339-343 | VB | denotes | show |
| T268 | 344-348 | IN | denotes | that |
| T269 | 349-352 | DT | denotes | the |
| T270 | 353-365 | VB | denotes | transforming |
| T271 | 366-372 | NN | denotes | growth |
| T272 | 373-381 | NN | denotes | factor-β |
| T273 | 382-383 | -LRB- | denotes | ( |
| T274 | 383-388 | NN | denotes | TGF-β |
| T275 | 388-389 | -RRB- | denotes | ) |
| T276 | 390-397 | VB | denotes | induces |
| T277 | 398-401 | DT | denotes | the |
| T278 | 402-412 | NN | denotes | expression |
| T279 | 413-415 | IN | denotes | of |
| T280 | 416-419 | DT | denotes | the |
| R83 | T224 | T225 | arg1Of | RUNX1,and |
| R84 | T225 | T222 | arg1Of | and,Transcription |
| R85 | T225 | T223 | arg1Of | and,factors |
| R86 | T225 | T227 | arg1Of | and,in |
| R87 | T225 | T230 | arg1Of | and,and |
| R88 | T226 | T225 | arg2Of | RUNX3,and |
| R89 | T229 | T227 | arg2Of | induction,in |
| R90 | T229 | T228 | arg1Of | induction,the |
| R91 | T232 | T230 | arg2Of | function,and |
| R92 | T232 | T231 | arg1Of | function,suppressive |
| R93 | T232 | T233 | arg1Of | function,of |
| R94 | T237 | T233 | arg2Of | cells,of |
| R95 | T237 | T234 | arg1Of | cells,Foxp3+ inducible |
| R96 | T237 | T235 | arg1Of | cells,regulatory |
| R97 | T237 | T236 | arg1Of | cells,T |
| R98 | T240 | T238 | arg1Of | P3,Forkhead |
| R99 | T240 | T239 | arg1Of | P3,box |
| R100 | T240 | T241 | arg1Of | P3,( |
| R101 | T240 | T244 | arg1Of | P3,+CD4+CD25+ |
| R102 | T242 | T241 | arg2Of | FOXP3,( |
| R103 | T243 | T241 | arg3Of | ),( |
| R104 | T244 | T253 | arg1Of | +CD4+CD25+,play |
| R105 | T249 | T248 | arg2Of | iT,( |
| R106 | T249 | T250 | arg1Of | iT,reg |
| R107 | T251 | T248 | arg3Of | ),( |
| R108 | T252 | T244 | arg2Of | cells,+CD4+CD25+ |
| R109 | T252 | T245 | arg1Of | cells,inducible |
| R110 | T252 | T246 | arg1Of | cells,regulatory |
| R111 | T252 | T247 | arg1Of | cells,T |
| R112 | T252 | T248 | arg1Of | cells,( |
| R113 | T253 | T257 | arg1Of | play,in |
| R114 | T256 | T253 | arg2Of | role,play |
| R115 | T256 | T254 | arg1Of | role,an |
| R116 | T256 | T255 | arg1Of | role,important |
| R117 | T259 | T260 | arg1Of | tolerance,and |
| R118 | T260 | T257 | arg2Of | and,in |
| R119 | T260 | T258 | arg1Of | and,immune |
| R120 | T261 | T260 | arg2Of | homeostasis,and |
| R121 | T264 | T262 | arg2Of | study,In |
| R122 | T264 | T263 | arg1Of | study,this |
| R123 | T266 | T267 | arg1Of | we,show |
| R124 | T267 | T262 | arg1Of | show,In |
| R125 | T267 | T265 | arg1Of | show,"," |
| R126 | T272 | T269 | arg1Of | factor-β,the |
| R127 | T272 | T270 | arg1Of | factor-β,transforming |
| R128 | T272 | T271 | arg1Of | factor-β,growth |
| R129 | T272 | T273 | arg1Of | factor-β,( |
| R130 | T272 | T276 | arg1Of | factor-β,induces |
| R131 | T274 | T273 | arg2Of | TGF-β,( |
| R132 | T275 | T273 | arg3Of | ),( |
| R133 | T276 | T267 | arg2Of | induces,show |
| R134 | T276 | T268 | arg1Of | induces,that |
| R135 | T278 | T276 | arg2Of | expression,induces |
| R136 | T278 | T277 | arg1Of | expression,the |
| R137 | T278 | T279 | arg1Of | expression,of |
bionlp-st-ge-2016-spacy-parsed
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T521 | 0-13 | NNP | denotes | Transcription |
| T522 | 14-21 | NNS | denotes | factors |
| T523 | 22-27 | NNP | denotes | RUNX1 |
| T524 | 28-31 | CC | denotes | and |
| T525 | 32-37 | NNP | denotes | RUNX3 |
| T526 | 38-40 | IN | denotes | in |
| T527 | 41-44 | DT | denotes | the |
| T528 | 45-54 | NN | denotes | induction |
| T529 | 55-58 | CC | denotes | and |
| T530 | 59-70 | JJ | denotes | suppressive |
| T531 | 71-79 | NN | denotes | function |
| T532 | 80-82 | IN | denotes | of |
| T533 | 83-88 | JJ | denotes | Foxp3 |
| T534 | 88-89 | NN | denotes | + |
| T535 | 90-99 | JJ | denotes | inducible |
| T536 | 100-110 | JJ | denotes | regulatory |
| T537 | 111-112 | NNP | denotes | T |
| T538 | 113-118 | NNS | denotes | cells |
| T539 | 189-197 | NNP | denotes | Forkhead |
| T540 | 198-201 | NN | denotes | box |
| T541 | 202-204 | NN | denotes | P3 |
| T542 | 205-206 | -LRB- | denotes | ( |
| T543 | 206-211 | CD | denotes | FOXP3 |
| T544 | 211-212 | -RRB- | denotes | ) |
| T545 | 212-213 | FW | denotes | + |
| T546 | 213-216 | FW | denotes | CD4 |
| T547 | 216-217 | FW | denotes | + |
| T548 | 217-221 | FW | denotes | CD25 |
| T549 | 221-222 | FW | denotes | + |
| T550 | 223-232 | FW | denotes | inducible |
| T551 | 233-243 | JJ | denotes | regulatory |
| T552 | 244-245 | NNP | denotes | T |
| T553 | 246-247 | -LRB- | denotes | ( |
| T554 | 247-249 | NNP | denotes | iT |
| T555 | 250-253 | NN | denotes | reg |
| T556 | 253-254 | -RRB- | denotes | ) |
| T557 | 255-260 | NNS | denotes | cells |
| T558 | 261-265 | VBP | denotes | play |
| T559 | 266-268 | DT | denotes | an |
| T560 | 269-278 | JJ | denotes | important |
| T561 | 279-283 | NN | denotes | role |
| T562 | 284-286 | IN | denotes | in |
| T563 | 287-293 | JJ | denotes | immune |
| T564 | 294-303 | NN | denotes | tolerance |
| T565 | 304-307 | CC | denotes | and |
| T566 | 308-319 | NN | denotes | homeostasis |
| T567 | 319-320 | . | denotes | . |
| T568 | 321-323 | IN | denotes | In |
| T569 | 324-328 | DT | denotes | this |
| T570 | 329-334 | NN | denotes | study |
| T571 | 334-335 | , | denotes | , |
| T572 | 336-338 | PRP | denotes | we |
| T573 | 339-343 | VBP | denotes | show |
| T574 | 344-348 | IN | denotes | that |
| T575 | 349-352 | DT | denotes | the |
| T576 | 353-365 | VBG | denotes | transforming |
| T577 | 366-372 | NN | denotes | growth |
| T578 | 373-381 | NN | denotes | factor-β |
| T579 | 382-383 | -LRB- | denotes | ( |
| T580 | 383-388 | NNP | denotes | TGF-β |
| T581 | 388-389 | -RRB- | denotes | ) |
| T582 | 390-397 | VBZ | denotes | induces |
| T583 | 398-401 | DT | denotes | the |
| T584 | 402-412 | NN | denotes | expression |
| T585 | 413-415 | IN | denotes | of |
| T586 | 416-419 | DT | denotes | the |
| R316 | T521 | T522 | compound | Transcription,factors |
| R317 | T522 | T558 | nsubj | factors,play |
| R318 | T523 | T552 | nmod | RUNX1,T |
| R319 | T524 | T523 | cc | and,RUNX1 |
| R320 | T525 | T523 | conj | RUNX3,RUNX1 |
| R321 | T526 | T523 | prep | in,RUNX1 |
| R322 | T527 | T528 | det | the,induction |
| R323 | T528 | T531 | nmod | induction,function |
| R324 | T529 | T528 | cc | and,induction |
| R325 | T530 | T531 | amod | suppressive,function |
| R326 | T531 | T526 | pobj | function,in |
| R327 | T532 | T531 | prep | of,function |
| R328 | T533 | T538 | amod | Foxp3,cells |
| R329 | T534 | T538 | nmod | +,cells |
| R330 | T535 | T538 | amod | inducible,cells |
| R331 | T536 | T538 | amod | regulatory,cells |
| R332 | T537 | T538 | compound | T,cells |
| R333 | T538 | T532 | pobj | cells,of |
| R334 | T539 | T541 | nmod | Forkhead,P3 |
| R335 | T540 | T541 | compound | box,P3 |
| R336 | T541 | T523 | conj | P3,RUNX1 |
| R337 | T542 | T541 | punct | (,P3 |
| R338 | T543 | T541 | appos | FOXP3,P3 |
| R339 | T544 | T541 | punct | ),P3 |
| R340 | T545 | T552 | nmod | +,T |
| R341 | T546 | T552 | nmod | CD4,T |
| R342 | T547 | T552 | nmod | +,T |
| R343 | T548 | T552 | nmod | CD25,T |
| R344 | T549 | T550 | nmod | +,inducible |
| R345 | T550 | T552 | nmod | inducible,T |
| R346 | T551 | T552 | amod | regulatory,T |
| R347 | T552 | T557 | nmod | T,cells |
| R348 | T553 | T555 | punct | (,reg |
| R349 | T554 | T555 | compound | iT,reg |
| R350 | T555 | T552 | appos | reg,T |
| R351 | T556 | T557 | punct | ),cells |
| R352 | T557 | T558 | nsubj | cells,play |
| R353 | T558 | T558 | ROOT | play,play |
| R354 | T559 | T561 | det | an,role |
| R355 | T560 | T561 | amod | important,role |
| R356 | T561 | T558 | dobj | role,play |
| R357 | T562 | T558 | prep | in,play |
| R358 | T563 | T564 | amod | immune,tolerance |
| R359 | T564 | T562 | pobj | tolerance,in |
| R360 | T565 | T564 | cc | and,tolerance |
| R361 | T566 | T564 | conj | homeostasis,tolerance |
| R362 | T567 | T558 | punct | .,play |
| R363 | T568 | T573 | prep | In,show |
| R364 | T569 | T570 | det | this,study |
| R365 | T570 | T568 | pobj | study,In |
| R366 | T571 | T573 | punct | ",",show |
| R367 | T572 | T573 | nsubj | we,show |
| R368 | T573 | T573 | ROOT | show,show |
| R369 | T574 | T582 | mark | that,induces |
| R370 | T575 | T578 | det | the,factor-β |
| R371 | T576 | T578 | amod | transforming,factor-β |
| R372 | T577 | T578 | compound | growth,factor-β |
| R373 | T578 | T582 | nsubj | factor-β,induces |
| R374 | T579 | T580 | punct | (,TGF-β |
| R375 | T580 | T578 | appos | TGF-β,factor-β |
| R376 | T581 | T578 | punct | ),factor-β |
| R377 | T582 | T573 | ccomp | induces,show |
| R378 | T583 | T584 | det | the,expression |
| R379 | T584 | T582 | dobj | expression,induces |
| R380 | T585 | T584 | prep | of,expression |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T788 | 0-13 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | Transcription |
| T791 | 308-319 | http://purl.obolibrary.org/obo/GO_0042592 | denotes | homeostasis |
| T792 | 366-372 | http://purl.obolibrary.org/obo/GO_0040007 | denotes | growth |
GO-MF
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T868 | 366-381 | http://purl.obolibrary.org/obo/GO_0005160 | denotes | growth factor-β |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T872 | 113-118 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T873 | 255-260 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T138 | 0-118 | Sentence | denotes | Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+ inducible regulatory T cells |
| T139 | 189-320 | Sentence | denotes | Forkhead box P3 (FOXP3)+CD4+CD25+ inducible regulatory T (iT reg) cells play an important role in immune tolerance and homeostasis. |
| T1 | 0-177 | Sentence | denotes | Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+ inducible regulatory T cells RUNX1 and RUNX3 in functional inducible T regulatory cells |
| T2 | 180-188 | Sentence | denotes | Abstract |
| T3 | 189-320 | Sentence | denotes | Forkhead box P3 (FOXP3)+CD4+CD25+ inducible regulatory T (iT reg) cells play an important role in immune tolerance and homeostasis. |
events-check-again
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T960 | 22-27 | Protein | denotes | RUNX1 |
| T961 | 32-37 | Protein | denotes | RUNX3 |
| T962 | 83-88 | Protein | denotes | Foxp3 |
| T963 | 189-204 | Protein | denotes | Forkhead box P3 |
| T964 | 206-211 | Protein | denotes | FOXP3 |
| T965 | 213-216 | Protein | denotes | CD4 |
| T966 | 217-221 | Protein | denotes | CD25 |
| T967 | 353-381 | Protein | denotes | transforming growth factor-β |
| T968 | 383-388 | Protein | denotes | TGF-β |
| T969 | 390-397 | Positive_regulation | denotes | induces |
| T970 | 390-397 | Positive_regulation | denotes | induces |
| T971 | 402-412 | Gene_expression | denotes | expression |
| T972 | 402-412 | Gene_expression | denotes | expression |
| R667 | T964 | T963 | equivalentTo | FOXP3,Forkhead box P3 |
| R668 | T967 | T968 | equivalentTo | transforming growth factor-β,TGF-β |
| R669 | T968 | T969 | causeOf | TGF-β,induces |
| R670 | T968 | T970 | causeOf | TGF-β,induces |
| R671 | T971 | T969 | themeOf | expression,induces |
| R672 | T972 | T970 | themeOf | expression,induces |
bionlp-st-ge-2016-reference
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T148 | 390-397 | Positive_regulation | denotes | induces |
| T159 | 402-412 | Gene_expression | denotes | expression |
| T168 | 390-397 | Positive_regulation | denotes | induces |
| T169 | 402-412 | Gene_expression | denotes | expression |
| T175 | 22-27 | Protein | denotes | RUNX1 |
| T208 | 189-204 | Protein | denotes | Forkhead box P3 |
| T214 | 206-211 | Protein | denotes | FOXP3 |
| T217 | 213-216 | Protein | denotes | CD4 |
| T218 | 217-221 | Protein | denotes | CD25 |
| T219 | 353-381 | Protein | denotes | transforming growth factor-β |
| T220 | 383-388 | Protein | denotes | TGF-β |
| T186 | 32-37 | Protein | denotes | RUNX3 |
| T197 | 83-88 | Protein | denotes | Foxp3 |
| R57 | T159 | T148 | themeOf | expression,induces |
| R60 | T169 | T168 | themeOf | expression,induces |
| R73 | T214 | T208 | equivalentTo | FOXP3,Forkhead box P3 |
| R79 | T219 | T220 | equivalentTo | transforming growth factor-β,TGF-β |
| R80 | T220 | T148 | causeOf | TGF-β,induces |
| R81 | T220 | T168 | causeOf | TGF-β,induces |
bionlp-st-ge-2016-uniprot
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T461 | 22-27 | Q01196 | denotes | RUNX1 |
| T462 | 32-37 | Q13761 | denotes | RUNX3 |
| T463 | 83-88 | Q9BZS1 | denotes | Foxp3 |
| T464 | 206-211 | Q9BZS1 | denotes | FOXP3 |
| T465 | 213-216 | P01730 | denotes | CD4 |
| T466 | 217-221 | P01589 | denotes | CD25 |
| T467 | 353-381 | P01137 | denotes | transforming growth factor-β |
| T468 | 383-388 | P01137 | denotes | TGF-β |
test2
| Id | Subject | Object | Predicate | Lexical cue | Speculation |
|---|---|---|---|---|---|
| T75 | 22-27 | Protein | denotes | RUNX1 | |
| T76 | 32-37 | Protein | denotes | RUNX3 | |
| T77 | 83-88 | Protein | denotes | Foxp3 | |
| T78 | 189-204 | Protein | denotes | Forkhead box P3 | |
| T79 | 206-211 | Protein | denotes | FOXP3 | true |
| T80 | 213-216 | Protein | denotes | CD4 | |
| T81 | 217-221 | Protein | denotes | CD25 | true |
| T82 | 353-381 | Protein | denotes | transforming growth factor-β | |
| T83 | 383-388 | Protein | denotes | TGF-β | |
| T84 | 390-397 | Positive_regulation | denotes | induces | |
| T85 | 402-412 | Gene_expression | denotes | expression | |
| R709 | T79 | T78 | equivalentTo | FOXP3,Forkhead box P3 | |
| R710 | T82 | T83 | equivalentTo | transforming growth factor-β,TGF-β | |
| R711 | T82 | T84 | causeOf | transforming growth factor-β,induces | |
| R712 | T83 | T84 | causeOf | TGF-β,induces | |
| R713 | T85 | T84 | themeOf | expression,induces |