PMC:2800179 / 25764-29489 JSON TXT

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GO-CC

Id	Subject	Object	Predicate	Lexical cue
T10958	233-243	http://purl.obolibrary.org/obo/GO_0000502	denotes	proteasome
T10959	699-703	http://purl.obolibrary.org/obo/GO_0005623	denotes	cell
T10960	995-999	http://purl.obolibrary.org/obo/GO_0005623	denotes	cell
T10961	1384-1389	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T10962	1576-1581	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T10963	1838-1843	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T10964	699-711	http://purl.obolibrary.org/obo/GO_0005634	denotes	cell nucleus
T10965	995-1007	http://purl.obolibrary.org/obo/GO_0005634	denotes	cell nucleus
T10966	704-711	http://purl.obolibrary.org/obo/GO_0005634	denotes	nucleus
T10967	1000-1007	http://purl.obolibrary.org/obo/GO_0005634	denotes	nucleus
T10968	1559-1566	http://purl.obolibrary.org/obo/GO_0005634	denotes	nucleus
T10969	1265-1275	http://purl.obolibrary.org/obo/GO_0019815	denotes	antibodies
T10970	1265-1275	http://purl.obolibrary.org/obo/GO_0042571	denotes	antibodies
T18163	2287-2292	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T18164	2484-2489	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T18165	2798-2803	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T18166	3352-3357	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T18167	3457-3462	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T18168	3647-3655	http://purl.obolibrary.org/obo/GO_0019815	denotes	antibody
T18169	3647-3655	http://purl.obolibrary.org/obo/GO_0042571	denotes	antibody

GO-MF

Id	Subject	Object	Predicate	Lexical cue
T10952	443-462	http://purl.obolibrary.org/obo/GO_0045289	denotes	luciferase activity
T10953	443-462	http://purl.obolibrary.org/obo/GO_0047077	denotes	luciferase activity
T10954	443-462	http://purl.obolibrary.org/obo/GO_0047712	denotes	luciferase activity
T10955	443-462	http://purl.obolibrary.org/obo/GO_0050248	denotes	luciferase activity
T10956	443-462	http://purl.obolibrary.org/obo/GO_0050397	denotes	luciferase activity
T10957	1265-1275	http://purl.obolibrary.org/obo/GO_0003823	denotes	antibodies
T18161	3151-3154	http://purl.obolibrary.org/obo/GO_0004707	denotes	ERK
T18162	3647-3655	http://purl.obolibrary.org/obo/GO_0003823	denotes	antibody

GO-BP

Id	Subject	Object	Predicate	Lexical cue
T10932	0-8	http://purl.obolibrary.org/obo/GO_0009056	denotes	Degraded
T10933	218-229	http://purl.obolibrary.org/obo/GO_0009056	denotes	degradation
T10934	1783-1794	http://purl.obolibrary.org/obo/GO_0009056	denotes	degradation
T10935	1893-1904	http://purl.obolibrary.org/obo/GO_0009056	denotes	degradation
T10936	1976-1984	http://purl.obolibrary.org/obo/GO_0009056	denotes	degraded
T10937	2136-2144	http://purl.obolibrary.org/obo/GO_0009056	denotes	degraded
T10938	61-80	http://purl.obolibrary.org/obo/GO_0010467	denotes	expression of genes
T10939	168-183	http://purl.obolibrary.org/obo/GO_0016310	denotes	phosphorylation
T10940	218-243	http://purl.obolibrary.org/obo/GO_1903009	denotes	degradation by proteasome
T10941	267-290	http://purl.obolibrary.org/obo/GO_0051092	denotes	activation of the NF-κB
T10942	329-345	http://purl.obolibrary.org/obo/GO_0051092	denotes	NF-κB activation
T10943	506-522	http://purl.obolibrary.org/obo/GO_0051092	denotes	NF-κB activation
T10944	1133-1152	http://purl.obolibrary.org/obo/GO_0051092	denotes	activation of NF-κB
T10945	443-462	http://purl.obolibrary.org/obo/GO_0045289	denotes	luciferase activity
T10946	443-462	http://purl.obolibrary.org/obo/GO_0047077	denotes	luciferase activity
T10947	443-462	http://purl.obolibrary.org/obo/GO_0047712	denotes	luciferase activity
T10948	443-462	http://purl.obolibrary.org/obo/GO_0050248	denotes	luciferase activity
T10949	443-462	http://purl.obolibrary.org/obo/GO_0050397	denotes	luciferase activity
T10950	1546-1566	http://purl.obolibrary.org/obo/GO_0042348	denotes	NF-κB in the nucleus
T10951	2083-2095	http://purl.obolibrary.org/obo/GO_0051179	denotes	localisation
T18155	2223-2231	http://purl.obolibrary.org/obo/GO_0009056	denotes	Degraded
T18156	2734-2742	http://purl.obolibrary.org/obo/GO_0009056	denotes	Degraded
T18157	3268-3276	http://purl.obolibrary.org/obo/GO_0009056	denotes	Degraded
T18158	2771-2790	http://purl.obolibrary.org/obo/GO_0051092	denotes	activation of NF-κB
T18159	3304-3323	http://purl.obolibrary.org/obo/GO_0051092	denotes	activation of NF-κB
T18160	3151-3154	http://purl.obolibrary.org/obo/GO_0004707	denotes	ERK

pmc-enju-pas

Id	Subject	Object	Predicate	Lexical cue
T10080	0-8	VB	denotes	Degraded
T10081	9-12	NNP	denotes	CGN
T10082	13-19	NNP	denotes	Induce
T10083	20-23	NNP	denotes	IκB
T10084	24-35	NNP	denotes	Degradation
T10085	36-39	CC	denotes	and
T10086	40-45	NN	denotes	NF-κB
T10087	46-56	NN	denotes	Activation
T10088	57-60	DT	denotes	The
T10089	61-71	NN	denotes	expression
T10090	72-74	IN	denotes	of
T10091	75-80	NN	denotes	genes
T10092	81-89	VB	denotes	encoding
T10093	90-93	IN	denotes	for
T10094	94-100	NN	denotes	ICAM-1
T10095	101-104	CC	denotes	and
T10096	105-110	NN	denotes	TNF-α
T10097	111-113	VB	denotes	is
T10098	114-124	VB	denotes	controlled
T10099	125-127	IN	denotes	by
T10100	128-131	DT	denotes	the
T10101	132-139	JJ	denotes	nuclear
T10102	140-146	NN	denotes	factor
T10103	147-152	NN	denotes	NF-κB
T10104	154-167	JJ	denotes	Site-specific
T10105	168-183	NN	denotes	phosphorylation
T10106	184-186	IN	denotes	of
T10107	187-190	DT	denotes	the
T10108	191-200	NN	denotes	inhibitor
T10109	201-204	NN	denotes	IκB
T10110	205-210	VB	denotes	leads
T10111	211-213	TO	denotes	to
T10112	214-217	PRP-DOLLAR-	denotes	its
T10113	218-229	NN	denotes	degradation
T10114	230-232	IN	denotes	by
T10115	233-243	NN	denotes	proteasome
T10116	244-247	CC	denotes	and
T10117	248-250	TO	denotes	to
T10118	251-252	DT	denotes	a
T10119	253-266	JJ	denotes	consequential
T10120	267-277	NN	denotes	activation
T10121	278-280	IN	denotes	of
T10122	281-284	DT	denotes	the
T10123	285-290	NN	denotes	NF-κB
T10124	291-298	NN	denotes	pathway
T10125	300-305	VB	denotes	Using
T10126	306-307	DT	denotes	a
T10127	308-316	NN	denotes	reporter
T10128	317-324	NN	denotes	plasmid
T10129	325-328	IN	denotes	for
T10130	329-334	NN	denotes	NF-κB
T10131	335-345	NN	denotes	activation
T10132	345-346	-COMMA-	denotes	,
T10133	347-349	PRP	denotes	it
T10134	350-353	VB	denotes	was
T10135	354-363	VB	denotes	confirmed
T10136	364-368	IN	denotes	that
T10137	369-373	NN	denotes	dCGN
T10138	374-381	VB	denotes	induced
T10139	382-383	DT	denotes	a
T10140	384-390	JJ	denotes	strong
T10141	391-401	NN	denotes	activation
T10142	402-404	IN	denotes	of
T10143	405-410	NN	denotes	NF-κB
T10144	410-411	-COMMA-	denotes	,
T10145	412-414	IN	denotes	as
T10146	415-424	VB	denotes	reflected
T10147	425-427	IN	denotes	by
T10148	428-430	DT	denotes	an
T10149	431-439	NN	denotes	increase
T10150	440-442	IN	denotes	in
T10151	443-453	NN	denotes	luciferase
T10152	454-462	NN	denotes	activity
T10153	463-464	-LRB-	denotes	(
T10154	464-468	NNP	denotes	Fig.
T10155	469-471	NN	denotes	7A
T10156	471-472	-RRB-	denotes	)
T10157	474-478	DT	denotes	Both
T10158	479-484	NN	denotes	forms
T10159	485-487	IN	denotes	of
T10160	488-492	NN	denotes	dCGN
T10161	493-497	VB	denotes	used
T10162	498-505	VB	denotes	induced
T10163	506-511	NN	denotes	NF-κB
T10164	512-522	NN	denotes	activation
T10165	523-525	IN	denotes	in
T10166	526-527	DT	denotes	a
T10167	528-532	NN	denotes	dose
T10168	533-542	JJ	denotes	dependent
T10169	543-549	NN	denotes	manner
T10170	551-558	RB	denotes	However
T10171	558-559	-COMMA-	denotes	,
T10172	560-563	DT	denotes	the
T10173	564-570	NN	denotes	effect
T10174	571-574	VB	denotes	was
T10175	575-579	RB	denotes	more
T10176	580-588	RB	denotes	strongly
T10177	589-596	VB	denotes	induced
T10178	597-599	IN	denotes	by
T10179	600-603	DT	denotes	the
T10180	604-606	CD	denotes	40
T10181	607-610	NN	denotes	kDa
T10182	611-615	NN	denotes	dCGN
T10183	616-617	-LRB-	denotes	(
T10184	617-621	NNP	denotes	Fig.
T10185	622-624	NN	denotes	7A
T10186	624-625	-RRB-	denotes	)
T10187	627-632	DT	denotes	These
T10188	633-640	NN	denotes	results
T10189	641-645	VB	denotes	were
T10190	646-653	RB	denotes	further
T10191	654-663	VB	denotes	confirmed
T10192	664-666	IN	denotes	by
T10193	667-675	RB	denotes	directly
T10194	676-685	VB	denotes	detecting
T10195	686-691	NN	denotes	NF-κB
T10196	692-694	IN	denotes	in
T10197	695-698	DT	denotes	the
T10198	699-703	NN	denotes	cell
T10199	704-711	NN	denotes	nucleus
T10200	712-714	IN	denotes	by
T10201	715-722	JJ	denotes	Western
T10202	723-731	NN	denotes	blotting
T10203	732-733	-LRB-	denotes	(
T10204	733-737	NN	denotes	Fig.
T10205	738-740	NN	denotes	7C
T10206	740-741	-RRB-	denotes	)
T10207	742-745	CC	denotes	and
T10208	746-748	IN	denotes	by
T10209	749-753	NN	denotes	FACS
T10210	754-755	-LRB-	denotes	(
T10211	755-759	NNP	denotes	Fig.
T10212	760-762	NN	denotes	7D
T10213	762-763	-RRB-	denotes	)
T10214	765-770	DT	denotes	These
T10215	771-777	NN	denotes	assays
T10216	778-782	RB	denotes	also
T10217	783-790	VB	denotes	allowed
T10218	791-793	PRP	denotes	us
T10219	794-796	TO	denotes	to
T10220	797-806	VB	denotes	determine
T10221	807-811	WP	denotes	what
T10222	812-817	NN	denotes	NF-κB
T10223	818-826	NN	denotes	subunits
T10224	827-831	VB	denotes	were
T10225	832-841	VB	denotes	activated
T10226	842-844	IN	denotes	by
T10227	845-849	NN	denotes	dCGN
T10228	851-855	DT	denotes	Both
T10229	856-861	NN	denotes	forms
T10230	862-863	-LRB-	denotes	(
T10231	863-865	CD	denotes	10
T10232	866-868	CC	denotes	or
T10233	869-871	CD	denotes	40
T10234	872-875	NN	denotes	kDa
T10235	875-876	-RRB-	denotes	)
T10236	877-879	IN	denotes	of
T10237	880-884	NN	denotes	dCGN
T10238	885-892	VB	denotes	induced
T10239	893-903	NN	denotes	activation
T10240	904-906	IN	denotes	of
T10241	907-910	DT	denotes	the
T10242	911-914	NN	denotes	p50
T10243	915-918	CC	denotes	and
T10244	919-922	NN	denotes	p65
T10245	923-931	NN	denotes	subunits
T10246	932-934	IN	denotes	of
T10247	935-940	NN	denotes	NF-κB
T10248	942-946	DT	denotes	This
T10249	947-954	JJ	denotes	nuclear
T10250	955-961	NN	denotes	factor
T10251	962-965	VB	denotes	was
T10252	966-973	JJ	denotes	present
T10253	974-976	IN	denotes	in
T10254	977-980	JJ	denotes	low
T10255	981-987	NN	denotes	levels
T10256	988-990	IN	denotes	in
T10257	991-994	DT	denotes	the
T10258	995-999	NN	denotes	cell
T10259	1000-1007	NN	denotes	nucleus
T10260	1008-1011	CC	denotes	and
T10261	1012-1021	VB	denotes	increased
T10262	1022-1034	RB	denotes	considerably
T10263	1035-1040	IN	denotes	after
T10264	1041-1050	NN	denotes	treatment
T10265	1051-1055	IN	denotes	with
T10266	1056-1060	NN	denotes	dCGN
T10267	1062-1069	JJ	denotes	Western
T10268	1070-1075	NN	denotes	blots
T10269	1076-1085	VB	denotes	suggested
T10270	1086-1089	DT	denotes	the
T10271	1090-1093	DT	denotes	the
T10272	1094-1096	CD	denotes	40
T10273	1097-1100	NN	denotes	kDa
T10274	1101-1105	NN	denotes	form
T10275	1106-1108	IN	denotes	of
T10276	1109-1113	NN	denotes	dCGN
T10277	1114-1121	VB	denotes	induced
T10278	1122-1123	DT	denotes	a
T10279	1124-1132	JJ	denotes	stronger
T10280	1133-1143	NN	denotes	activation
T10281	1144-1146	IN	denotes	of
T10282	1147-1152	NN	denotes	NF-κB
T10283	1153-1154	-LRB-	denotes	(
T10284	1154-1158	NNP	denotes	Fig.
T10285	1159-1161	NN	denotes	7C
T10286	1161-1162	-RRB-	denotes	)
T10287	1164-1165	DT	denotes	A
T10288	1166-1170	RB	denotes	more
T10289	1171-1178	JJ	denotes	sentive
T10290	1179-1184	NN	denotes	assay
T10291	1185-1188	IN	denotes	for
T10292	1189-1196	JJ	denotes	nuclear
T10293	1197-1203	NN	denotes	factor
T10294	1204-1214	NN	denotes	activation
T10295	1215-1217	VB	denotes	is
T10296	1218-1222	NN	denotes	flow
T10297	1223-1232	NN	denotes	cytometry
T10298	1233-1235	IN	denotes	of
T10299	1236-1242	NN	denotes	nuclei
T10300	1243-1250	VB	denotes	stained
T10301	1251-1255	IN	denotes	with
T10302	1256-1264	JJ	denotes	specific
T10303	1265-1275	NN	denotes	antibodies
T10304	1276-1279	IN	denotes	for
T10305	1280-1283	DT	denotes	the
T10306	1284-1291	JJ	denotes	nuclear
T10307	1292-1298	NN	denotes	factor
T10308	1299-1301	IN	denotes	of
T10309	1302-1310	NN	denotes	interest
T10310	1312-1314	IN	denotes	In
T10311	1315-1324	NN	denotes	agreement
T10312	1325-1329	IN	denotes	with
T10313	1330-1333	DT	denotes	the
T10314	1334-1342	JJ	denotes	previous
T10315	1343-1347	NN	denotes	data
T10316	1347-1348	-COMMA-	denotes	,
T10317	1349-1353	NN	denotes	FACS
T10318	1354-1362	NN	denotes	analysis
T10319	1363-1365	IN	denotes	of
T10320	1366-1372	NN	denotes	nuclei
T10321	1373-1377	IN	denotes	from
T10322	1378-1383	NN	denotes	THP-1
T10323	1384-1389	NN	denotes	cells
T10324	1390-1396	VB	denotes	showed
T10325	1397-1401	IN	denotes	that
T10326	1402-1407	EX	denotes	there
T10327	1408-1411	VB	denotes	was
T10328	1412-1413	DT	denotes	a
T10329	1414-1419	JJ	denotes	basal
T10330	1420-1425	NN	denotes	level
T10331	1426-1428	IN	denotes	of
T10332	1429-1436	JJ	denotes	nuclear
T10333	1437-1442	NN	denotes	NF-κB
T10334	1443-1444	-LRB-	denotes	(
T10335	1444-1448	NNP	denotes	Fig.
T10336	1449-1451	NN	denotes	7D
T10337	1451-1452	-RRB-	denotes	)
T10338	1454-1459	RB	denotes	Again
T10339	1459-1460	-COMMA-	denotes	,
T10340	1461-1465	DT	denotes	both
T10341	1466-1471	NN	denotes	forms
T10342	1472-1473	-LRB-	denotes	(
T10343	1473-1475	CD	denotes	10
T10344	1476-1478	CC	denotes	or
T10345	1479-1481	CD	denotes	40
T10346	1482-1485	NN	denotes	kDa
T10347	1485-1486	-RRB-	denotes	)
T10348	1487-1489	IN	denotes	of
T10349	1490-1494	NN	denotes	dCGN
T10350	1495-1502	VB	denotes	induced
T10351	1503-1505	DT	denotes	an
T10352	1506-1514	NN	denotes	increase
T10353	1515-1517	IN	denotes	of
T10354	1518-1521	DT	denotes	the
T10355	1522-1525	NN	denotes	p50
T10356	1526-1529	CC	denotes	and
T10357	1530-1533	NN	denotes	p65
T10358	1534-1542	NN	denotes	subunits
T10359	1543-1545	IN	denotes	of
T10360	1546-1551	NN	denotes	NF-κB
T10361	1552-1554	IN	denotes	in
T10362	1555-1558	DT	denotes	the
T10363	1559-1566	NN	denotes	nucleus
T10364	1567-1569	IN	denotes	of
T10365	1570-1575	DT	denotes	these
T10366	1576-1581	NN	denotes	cells
T10367	1583-1586	DT	denotes	The
T10368	1587-1589	CD	denotes	40
T10369	1590-1593	NN	denotes	kDa
T10370	1594-1602	VB	denotes	degraded
T10371	1603-1606	NN	denotes	CGN
T10372	1607-1611	VB	denotes	gave
T10373	1612-1613	DT	denotes	a
T10374	1614-1622	JJ	denotes	stronger
T10375	1623-1631	NN	denotes	increase
T10376	1632-1634	IN	denotes	of
T10377	1635-1640	NN	denotes	NF-κB
T10378	1641-1642	-LRB-	denotes	(
T10379	1642-1646	NNP	denotes	Fig.
T10380	1647-1649	NN	denotes	7D
T10381	1649-1650	-RRB-	denotes	)
T10382	1652-1657	DT	denotes	These
T10383	1658-1662	NN	denotes	data
T10384	1663-1671	RB	denotes	strongly
T10385	1672-1679	VB	denotes	suggest
T10386	1680-1684	IN	denotes	that
T10387	1685-1688	DT	denotes	the
T10388	1689-1700	NN	denotes	heterodimer
T10389	1701-1708	NN	denotes	p50/p65
T10390	1709-1711	VB	denotes	is
T10391	1712-1715	DT	denotes	the
T10392	1716-1721	NN	denotes	NF-κB
T10393	1722-1729	NN	denotes	isoform
T10394	1730-1739	VB	denotes	activated
T10395	1740-1742	IN	denotes	by
T10396	1743-1751	VB	denotes	degraded
T10397	1752-1755	NN	denotes	CGN
T10398	1756-1758	IN	denotes	in
T10399	1759-1768	NN	denotes	monocytes
T10400	1770-1772	IN	denotes	In
T10401	1773-1781	NN	denotes	addition
T10402	1781-1782	-COMMA-	denotes	,
T10403	1783-1794	NN	denotes	degradation
T10404	1795-1797	IN	denotes	of
T10405	1798-1801	DT	denotes	the
T10406	1802-1811	NN	denotes	inhibitor
T10407	1812-1816	NN	denotes	IκBα
T10408	1817-1820	VB	denotes	was
T10409	1821-1825	RB	denotes	also
T10410	1826-1834	VB	denotes	observed
T10411	1835-1837	IN	denotes	in
T10412	1838-1843	NN	denotes	cells
T10413	1844-1851	VB	denotes	treated
T10414	1852-1856	IN	denotes	with
T10415	1857-1861	NN	denotes	dCGN
T10416	1862-1863	-LRB-	denotes	(
T10417	1863-1867	NNP	denotes	Fig.
T10418	1868-1870	NN	denotes	7B
T10419	1870-1871	-RRB-	denotes	)
T10420	1873-1875	DT	denotes	No
T10421	1876-1887	JJ	denotes	significant
T10422	1888-1892	NN	denotes	IκBα
T10423	1893-1904	NN	denotes	degradation
T10424	1905-1908	VB	denotes	was
T10425	1909-1917	VB	denotes	detected
T10426	1918-1924	IN	denotes	within
T10427	1925-1928	CD	denotes	two
T10428	1929-1934	NN	denotes	hours
T10429	1935-1937	IN	denotes	of
T10430	1938-1942	NN	denotes	dCGN
T10431	1943-1952	NN	denotes	treatment
T10432	1952-1953	-COMMA-	denotes	,
T10433	1954-1957	CC	denotes	but
T10434	1958-1962	NN	denotes	IκBα
T10435	1963-1966	VB	denotes	was
T10436	1967-1975	RB	denotes	markedly
T10437	1976-1984	VB	denotes	degraded
T10438	1985-1987	IN	denotes	by
T10439	1988-1992	CD	denotes	four
T10440	1993-1998	NN	denotes	hours
T10441	1999-2001	IN	denotes	of
T10442	2002-2006	NN	denotes	dCGN
T10443	2007-2016	NN	denotes	treatment
T10444	2017-2018	-LRB-	denotes	(
T10445	2018-2022	NN	denotes	Fig.
T10446	2023-2025	NN	denotes	7B
T10447	2025-2026	-RRB-	denotes	)
T10448	2028-2030	PRP	denotes	We
T10449	2031-2038	VB	denotes	focused
T10450	2039-2041	IN	denotes	on
T10451	2042-2046	NN	denotes	IκBα
T10452	2047-2054	NN	denotes	subunit
T10453	2054-2055	-COMMA-	denotes	,
T10454	2056-2061	IN	denotes	since
T10455	2062-2064	PRP	denotes	it
T10456	2065-2070	VB	denotes	masks
T10457	2071-2074	DT	denotes	the
T10458	2075-2082	JJ	denotes	nuclear
T10459	2083-2095	NN	denotes	localisation
T10460	2096-2104	NN	denotes	sequence
T10461	2105-2107	IN	denotes	of
T10462	2108-2111	NN	denotes	p65
T10463	2111-2112	-COMMA-	denotes	,
T10464	2113-2115	PRP	denotes	it
T10465	2116-2118	VB	denotes	is
T10466	2119-2122	DT	denotes	the
T10467	2123-2127	RB	denotes	most
T10468	2128-2135	RB	denotes	rapidly
T10469	2136-2144	VB	denotes	degraded
T10470	2145-2152	NN	denotes	subunit
T10471	2153-2156	CC	denotes	and
T10472	2157-2160	DT	denotes	the
T10473	2161-2165	RB	denotes	most
T10474	2166-2173	VB	denotes	studied
T10475	2174-2177	CD	denotes	one
T17542	2223-2231	VB	denotes	Degraded
T17543	2232-2235	NN	denotes	CGN
T17544	2236-2245	VB	denotes	activated
T17545	2246-2249	DT	denotes	the
T17546	2250-2255	NN	denotes	NF-kB
T17547	2256-2263	NN	denotes	pathway
T17548	2264-2266	IN	denotes	in
T17549	2267-2276	NN	denotes	monocytes
T17550	2278-2279	DT	denotes	A
T17551	2279-2280	-COLON-	denotes	:
T17552	2281-2286	NN	denotes	THP-1
T17553	2287-2292	NN	denotes	cells
T17554	2293-2297	VB	denotes	were
T17555	2298-2309	VB	denotes	transfected
T17556	2310-2314	IN	denotes	with
T17557	2315-2316	DT	denotes	a
T17558	2317-2322	NN	denotes	NF-κB
T17559	2323-2331	NN	denotes	reporter
T17560	2332-2339	NN	denotes	plasmid
T17561	2340-2347	VB	denotes	driving
T17562	2348-2358	NN	denotes	expression
T17563	2359-2361	IN	denotes	of
T17564	2362-2372	NN	denotes	luciferase
T17565	2374-2379	NN	denotes	Cells
T17566	2380-2384	VB	denotes	were
T17567	2385-2389	RB	denotes	then
T17568	2390-2397	VB	denotes	treated
T17569	2398-2402	IN	denotes	with
T17570	2403-2410	JJ	denotes	various
T17571	2411-2425	NN	denotes	concentrations
T17572	2426-2428	IN	denotes	of
T17573	2429-2431	CD	denotes	10
T17574	2432-2435	NN	denotes	kDa
T17575	2436-2437	-LRB-	denotes	(
T17576	2437-2446	NN	denotes	triangles
T17577	2446-2447	-RRB-	denotes	)
T17578	2447-2448	-COMMA-	denotes	,
T17579	2449-2451	CC	denotes	or
T17580	2452-2454	CD	denotes	40
T17581	2455-2458	NN	denotes	kDa
T17582	2459-2463	NN	denotes	dCGN
T17583	2464-2465	-LRB-	denotes	(
T17584	2465-2472	NN	denotes	squares
T17585	2472-2473	-RRB-	denotes	)
T17586	2475-2476	NN	denotes	B
T17587	2476-2477	-COLON-	denotes	:
T17588	2478-2483	NN	denotes	THP-1
T17589	2484-2489	NN	denotes	cells
T17590	2490-2497	VB	denotes	treated
T17591	2498-2502	IN	denotes	with
T17592	2503-2504	CD	denotes	1
T17593	2505-2510	NN	denotes	mg/ml
T17594	2511-2513	IN	denotes	of
T17595	2514-2516	CD	denotes	10
T17596	2517-2520	NN	denotes	kDa
T17597	2521-2525	NN	denotes	dCGN
T17598	2526-2527	-LRB-	denotes	(
T17599	2527-2530	NN	denotes	C10
T17600	2530-2531	-RRB-	denotes	)
T17601	2531-2532	-COMMA-	denotes	,
T17602	2533-2535	CC	denotes	or
T17603	2536-2540	IN	denotes	with
T17604	2541-2542	CD	denotes	1
T17605	2543-2548	NN	denotes	mg/ml
T17606	2549-2551	IN	denotes	of
T17607	2552-2554	CD	denotes	40
T17608	2555-2558	NN	denotes	kDa
T17609	2559-2563	NN	denotes	dCGN
T17610	2564-2565	-LRB-	denotes	(
T17611	2565-2568	NN	denotes	C40
T17612	2568-2569	-RRB-	denotes	)
T17613	2570-2574	VB	denotes	were
T17614	2575-2580	VB	denotes	lysed
T17615	2581-2586	IN	denotes	after
T17616	2587-2594	JJ	denotes	various
T17617	2595-2602	NN	denotes	periods
T17618	2603-2605	IN	denotes	of
T17619	2606-2610	NN	denotes	time
T17620	2612-2620	NN	denotes	Proteins
T17621	2621-2623	IN	denotes	in
T17622	2624-2628	NN	denotes	cell
T17623	2629-2637	NN	denotes	extracts
T17624	2638-2642	VB	denotes	were
T17625	2643-2651	VB	denotes	resolved
T17626	2652-2654	IN	denotes	by
T17627	2655-2663	NN	denotes	SDS-PAGE
T17628	2664-2667	CC	denotes	and
T17629	2668-2672	RB	denotes	then
T17630	2673-2680	JJ	denotes	Western
T17631	2681-2688	VB	denotes	blotted
T17632	2689-2692	IN	denotes	for
T17633	2693-2697	NN	denotes	IκBα
T17634	2698-2700	CC	denotes	or
T17635	2701-2710	NN	denotes	α−tubulin
T17636	2711-2713	IN	denotes	as
T17637	2714-2721	VB	denotes	loading
T17638	2722-2729	NN	denotes	control
T17639	2731-2732	NN	denotes	C
T17640	2732-2733	-COLON-	denotes	:
T17641	2734-2742	VB	denotes	Degraded
T17642	2743-2755	NN	denotes	carrageenans
T17643	2756-2757	-LRB-	denotes	(
T17644	2757-2761	NN	denotes	dCGN
T17645	2761-2762	-RRB-	denotes	)
T17646	2763-2770	VB	denotes	induced
T17647	2771-2781	NN	denotes	activation
T17648	2782-2784	IN	denotes	of
T17649	2785-2790	NN	denotes	NF-κB
T17650	2792-2797	NN	denotes	THP-1
T17651	2798-2803	NN	denotes	cells
T17652	2804-2808	VB	denotes	were
T17653	2809-2816	VB	denotes	treated
T17654	2817-2821	IN	denotes	with
T17655	2822-2829	NN	denotes	nothing
T17656	2830-2831	-LRB-	denotes	(
T17657	2831-2838	NN	denotes	control
T17658	2838-2839	-RRB-	denotes	)
T17659	2839-2840	-COMMA-	denotes	,
T17660	2841-2843	CC	denotes	or
T17661	2844-2848	IN	denotes	with
T17662	2849-2850	CD	denotes	1
T17663	2851-2856	NN	denotes	mg/ml
T17664	2857-2859	IN	denotes	of
T17665	2860-2862	CD	denotes	10
T17666	2863-2866	NN	denotes	kDa
T17667	2867-2871	NN	denotes	dCGN
T17668	2872-2873	-LRB-	denotes	(
T17669	2873-2876	NN	denotes	C10
T17670	2876-2877	-RRB-	denotes	)
T17671	2877-2878	-COMMA-	denotes	,
T17672	2879-2881	CC	denotes	or
T17673	2882-2886	IN	denotes	with
T17674	2887-2888	CD	denotes	1
T17675	2889-2894	NN	denotes	mg/ml
T17676	2895-2897	IN	denotes	of
T17677	2898-2900	CD	denotes	40
T17678	2901-2904	NN	denotes	kDa
T17679	2905-2909	NN	denotes	dCGN
T17680	2910-2911	-LRB-	denotes	(
T17681	2911-2914	NN	denotes	C40
T17682	2914-2915	-RRB-	denotes	)
T17683	2916-2919	IN	denotes	for
T17684	2920-2922	CD	denotes	30
T17685	2923-2930	NN	denotes	minutes
T17686	2931-2933	IN	denotes	at
T17687	2934-2939	NNP	denotes	37°C.
T17688	2940-2946	NNP	denotes	Nuclei
T17689	2947-2951	VB	denotes	were
T17690	2952-2960	VB	denotes	isolated
T17691	2961-2964	CC	denotes	and
T17692	2965-2970	VB	denotes	lysed
T17693	2972-2980	NN	denotes	Proteins
T17694	2981-2983	IN	denotes	in
T17695	2984-2991	JJ	denotes	nuclear
T17696	2992-3000	NN	denotes	extracts
T17697	3001-3005	VB	denotes	were
T17698	3006-3014	VB	denotes	resolved
T17699	3015-3017	IN	denotes	by
T17700	3018-3026	NN	denotes	SDS-PAGE
T17701	3027-3030	CC	denotes	and
T17702	3031-3035	RB	denotes	then
T17703	3036-3043	JJ	denotes	Western
T17704	3044-3051	VB	denotes	blotted
T17705	3052-3055	IN	denotes	for
T17706	3056-3061	NN	denotes	NF-κB
T17707	3062-3065	NN	denotes	p50
T17708	3066-3073	NN	denotes	subunit
T17709	3074-3075	-LRB-	denotes	(
T17710	3075-3078	NN	denotes	p50
T17711	3078-3079	-RRB-	denotes	)
T17712	3080-3082	CC	denotes	or
T17713	3083-3088	NN	denotes	NF-κB
T17714	3089-3092	NN	denotes	p65
T17715	3093-3100	NN	denotes	subunit
T17716	3101-3102	-LRB-	denotes	(
T17717	3102-3105	NN	denotes	p65
T17718	3105-3106	-RRB-	denotes	)
T17719	3108-3113	JJ	denotes	Lower
T17720	3114-3120	NN	denotes	panels
T17721	3121-3125	VB	denotes	show
T17722	3126-3133	JJ	denotes	Western
T17723	3134-3139	NN	denotes	blots
T17724	3140-3142	IN	denotes	of
T17725	3143-3150	JJ	denotes	nuclear
T17726	3151-3154	NN	denotes	ERK
T17727	3155-3164	VB	denotes	revealing
T17728	3165-3175	JJ	denotes	equivalent
T17729	3176-3182	NN	denotes	amount
T17730	3183-3185	IN	denotes	of
T17731	3186-3193	NN	denotes	protein
T17732	3194-3196	IN	denotes	in
T17733	3197-3201	DT	denotes	each
T17734	3202-3208	NN	denotes	sample
T17735	3210-3214	NN	denotes	Data
T17736	3215-3218	VB	denotes	are
T17737	3219-3233	JJ	denotes	representative
T17738	3234-3236	IN	denotes	of
T17739	3237-3242	CD	denotes	three
T17740	3243-3251	JJ	denotes	separate
T17741	3252-3263	NN	denotes	experiments
T17742	3265-3266	NN	denotes	D
T17743	3266-3267	-COLON-	denotes	:
T17744	3268-3276	VB	denotes	Degraded
T17745	3277-3288	NN	denotes	carrageenan
T17746	3289-3290	-LRB-	denotes	(
T17747	3290-3294	NN	denotes	dCGN
T17748	3294-3295	-RRB-	denotes	)
T17749	3296-3303	VB	denotes	induced
T17750	3304-3314	NN	denotes	activation
T17751	3315-3317	IN	denotes	of
T17752	3318-3323	NN	denotes	NF-κB
T17753	3325-3331	NN	denotes	Nuclei
T17754	3332-3340	VB	denotes	isolated
T17755	3341-3345	IN	denotes	from
T17756	3346-3351	NN	denotes	THP-1
T17757	3352-3357	NN	denotes	cells
T17758	3358-3362	VB	denotes	were
T17759	3363-3383	JJ	denotes	fluorescence-stained
T17760	3384-3387	IN	denotes	for
T17761	3388-3393	NN	denotes	NF-κB
T17762	3394-3397	NN	denotes	p50
T17763	3398-3405	NN	denotes	subunit
T17764	3406-3408	CC	denotes	or
T17765	3409-3414	NN	denotes	NF-κB
T17766	3415-3418	NN	denotes	p65
T17767	3419-3426	NN	denotes	subunit
T17768	3427-3433	IN	denotes	before
T17769	3434-3435	-LRB-	denotes	(
T17770	3435-3441	VB	denotes	filled
T17771	3442-3446	NN	denotes	area
T17772	3446-3447	-RRB-	denotes	)
T17773	3448-3450	CC	denotes	or
T17774	3451-3456	IN	denotes	after
T17775	3457-3462	NN	denotes	cells
T17776	3463-3467	VB	denotes	were
T17777	3468-3475	VB	denotes	treated
T17778	3476-3480	IN	denotes	with
T17779	3481-3482	CD	denotes	1
T17780	3483-3488	NN	denotes	mg/ml
T17781	3489-3491	IN	denotes	of
T17782	3492-3494	CD	denotes	10
T17783	3495-3498	NN	denotes	kDa
T17784	3499-3503	NN	denotes	dCGN
T17785	3504-3505	-LRB-	denotes	(
T17786	3505-3508	NN	denotes	C10
T17787	3508-3509	-RRB-	denotes	)
T17788	3509-3510	-COMMA-	denotes	,
T17789	3511-3513	CC	denotes	or
T17790	3514-3518	IN	denotes	with
T17791	3519-3520	CD	denotes	1
T17792	3521-3526	NN	denotes	mg/ml
T17793	3527-3529	IN	denotes	of
T17794	3530-3532	CD	denotes	40
T17795	3533-3536	NN	denotes	kDa
T17796	3537-3541	NN	denotes	dCGN
T17797	3542-3543	-LRB-	denotes	(
T17798	3543-3546	NN	denotes	C40
T17799	3546-3547	-RRB-	denotes	)
T17800	3548-3551	IN	denotes	for
T17801	3552-3554	CD	denotes	30
T17802	3555-3562	NN	denotes	minutes
T17803	3563-3565	IN	denotes	at
T17804	3566-3571	NNP	denotes	37°C.
T17805	3572-3578	NNP	denotes	Dashed
T17806	3579-3583	NN	denotes	line
T17807	3584-3595	VB	denotes	corresponds
T17808	3596-3598	TO	denotes	to
T17809	3599-3605	NN	denotes	nuclei
T17810	3606-3613	VB	denotes	stained
T17811	3614-3618	RB	denotes	only
T17812	3619-3623	IN	denotes	with
T17813	3624-3633	JJ	denotes	secondary
T17814	3634-3646	NN	denotes	fluorescence
T17815	3647-3655	NN	denotes	antibody
T17816	3657-3669	NN	denotes	Fluorescence
T17817	3670-3679	NN	denotes	intensity
T17818	3680-3683	VB	denotes	was
T17819	3684-3692	VB	denotes	analyzed
T17820	3693-3695	IN	denotes	by
T17821	3696-3700	NN	denotes	flow
T17822	3701-3710	NN	denotes	cytometry
T17823	3711-3713	IN	denotes	as
T17824	3714-3723	VB	denotes	described
R8690	T10084	T10081	arg1Of	Degradation,CGN
R8691	T10084	T10082	arg1Of	Degradation,Induce
R8692	T10084	T10083	arg1Of	Degradation,IκB
R8693	T10084	T10085	arg1Of	Degradation,and
R8694	T10086	T10085	arg2Of	NF-κB,and
R8695	T10087	T10080	arg2Of	Activation,Degraded
R8696	T10087	T10084	arg1Of	Activation,Degradation
R8697	T10087	T10086	arg1Of	Activation,NF-κB
R8698	T10089	T10088	arg1Of	expression,The
R8699	T10089	T10090	arg1Of	expression,of
R8700	T10089	T10097	arg1Of	expression,is
R8701	T10089	T10098	arg2Of	expression,controlled
R8702	T10091	T10090	arg2Of	genes,of
R8703	T10091	T10092	arg1Of	genes,encoding
R8704	T10092	T10093	arg1Of	encoding,for
R8705	T10094	T10095	arg1Of	ICAM-1,and
R8706	T10095	T10093	arg2Of	and,for
R8707	T10096	T10095	arg2Of	TNF-α,and
R8708	T10098	T10097	arg2Of	controlled,is
R8709	T10103	T10098	arg1Of	NF-κB,controlled
R8710	T10103	T10099	arg2Of	NF-κB,by
R8711	T10103	T10100	arg1Of	NF-κB,the
R8712	T10103	T10101	arg1Of	NF-κB,nuclear
R8713	T10103	T10102	arg1Of	NF-κB,factor
R8714	T10105	T10104	arg1Of	phosphorylation,Site-specific
R8715	T10105	T10106	arg1Of	phosphorylation,of
R8716	T10105	T10110	arg1Of	phosphorylation,leads
R8717	T10109	T10106	arg2Of	IκB,of
R8718	T10109	T10107	arg1Of	IκB,the
R8719	T10109	T10108	arg1Of	IκB,inhibitor
R8720	T10110	T10111	arg1Of	leads,to
R8721	T10110	T10117	arg1Of	leads,to
R8722	T10111	T10116	arg1Of	to,and
R8723	T10113	T10111	arg2Of	degradation,to
R8724	T10113	T10112	arg1Of	degradation,its
R8725	T10113	T10114	arg1Of	degradation,by
R8726	T10115	T10114	arg2Of	proteasome,by
R8727	T10117	T10116	arg2Of	to,and
R8728	T10120	T10117	arg2Of	activation,to
R8729	T10120	T10118	arg1Of	activation,a
R8730	T10120	T10119	arg1Of	activation,consequential
R8731	T10120	T10121	arg1Of	activation,of
R8732	T10124	T10121	arg2Of	pathway,of
R8733	T10124	T10122	arg1Of	pathway,the
R8734	T10124	T10123	arg1Of	pathway,NF-κB
R8735	T10128	T10125	arg2Of	plasmid,Using
R8736	T10128	T10126	arg1Of	plasmid,a
R8737	T10128	T10127	arg1Of	plasmid,reporter
R8738	T10128	T10129	arg1Of	plasmid,for
R8739	T10131	T10129	arg2Of	activation,for
R8740	T10131	T10130	arg1Of	activation,NF-κB
R8741	T10133	T10125	arg1Of	it,Using
R8742	T10133	T10134	arg1Of	it,was
R8743	T10133	T10135	arg2Of	it,confirmed
R8744	T10135	T10134	arg2Of	confirmed,was
R8745	T10135	T10136	arg1Of	confirmed,that
R8746	T10136	T10125	modOf	that,Using
R8747	T10136	T10132	arg1Of	that,","
R8748	T10136	T10145	arg1Of	that,as
R8749	T10137	T10138	arg1Of	dCGN,induced
R8750	T10138	T10136	arg2Of	induced,that
R8751	T10138	T10144	arg1Of	induced,","
R8752	T10141	T10138	arg2Of	activation,induced
R8753	T10141	T10139	arg1Of	activation,a
R8754	T10141	T10140	arg1Of	activation,strong
R8755	T10141	T10142	arg1Of	activation,of
R8756	T10143	T10142	arg2Of	NF-κB,of
R8757	T10146	T10145	arg2Of	reflected,as
R8758	T10149	T10146	arg1Of	increase,reflected
R8759	T10149	T10147	arg2Of	increase,by
R8760	T10149	T10148	arg1Of	increase,an
R8761	T10149	T10150	arg1Of	increase,in
R8762	T10152	T10150	arg2Of	activity,in
R8763	T10152	T10151	arg1Of	activity,luciferase
R8764	T10152	T10153	arg1Of	activity,(
R8765	T10155	T10153	arg2Of	7A,(
R8766	T10155	T10154	arg1Of	7A,Fig.
R8767	T10156	T10153	arg3Of	),(
R8768	T10158	T10157	arg1Of	forms,Both
R8769	T10158	T10159	arg1Of	forms,of
R8770	T10158	T10162	arg1Of	forms,induced
R8771	T10160	T10159	arg2Of	dCGN,of
R8772	T10160	T10161	arg2Of	dCGN,used
R8773	T10162	T10165	arg1Of	induced,in
R8774	T10164	T10162	arg2Of	activation,induced
R8775	T10164	T10163	arg1Of	activation,NF-κB
R8776	T10168	T10167	arg1Of	dependent,dose
R8777	T10169	T10165	arg2Of	manner,in
R8778	T10169	T10166	arg1Of	manner,a
R8779	T10169	T10168	arg1Of	manner,dependent
R8780	T10173	T10172	arg1Of	effect,the
R8781	T10173	T10174	arg1Of	effect,was
R8782	T10173	T10177	arg2Of	effect,induced
R8783	T10176	T10175	arg1Of	strongly,more
R8784	T10177	T10170	arg1Of	induced,However
R8785	T10177	T10171	arg1Of	induced,","
R8786	T10177	T10174	arg2Of	induced,was
R8787	T10177	T10176	arg1Of	induced,strongly
R8788	T10182	T10177	arg1Of	dCGN,induced
R8789	T10182	T10178	arg2Of	dCGN,by
R8790	T10182	T10179	arg1Of	dCGN,the
R8791	T10182	T10180	arg1Of	dCGN,40
R8792	T10182	T10181	arg1Of	dCGN,kDa
R8793	T10182	T10183	arg1Of	dCGN,(
R8794	T10185	T10183	arg2Of	7A,(
R8795	T10185	T10184	arg1Of	7A,Fig.
R8796	T10186	T10183	arg3Of	),(
R8797	T10188	T10187	arg1Of	results,These
R8798	T10188	T10189	arg1Of	results,were
R8799	T10188	T10191	arg2Of	results,confirmed
R8800	T10191	T10189	arg2Of	confirmed,were
R8801	T10191	T10190	arg1Of	confirmed,further
R8802	T10191	T10192	arg1Of	confirmed,by
R8803	T10194	T10192	arg2Of	detecting,by
R8804	T10194	T10193	arg1Of	detecting,directly
R8805	T10194	T10196	arg1Of	detecting,in
R8806	T10194	T10200	arg1Of	detecting,by
R8807	T10194	T10208	arg1Of	detecting,by
R8808	T10195	T10194	arg2Of	NF-κB,detecting
R8809	T10199	T10196	arg2Of	nucleus,in
R8810	T10199	T10197	arg1Of	nucleus,the
R8811	T10199	T10198	arg1Of	nucleus,cell
R8812	T10200	T10207	arg1Of	by,and
R8813	T10202	T10200	arg2Of	blotting,by
R8814	T10202	T10201	arg1Of	blotting,Western
R8815	T10202	T10203	arg1Of	blotting,(
R8816	T10205	T10203	arg2Of	7C,(
R8817	T10205	T10204	arg1Of	7C,Fig.
R8818	T10206	T10203	arg3Of	),(
R8819	T10208	T10207	arg2Of	by,and
R8820	T10209	T10208	arg2Of	FACS,by
R8821	T10209	T10210	arg1Of	FACS,(
R8822	T10212	T10210	arg2Of	7D,(
R8823	T10212	T10211	arg1Of	7D,Fig.
R8824	T10213	T10210	arg3Of	),(
R8825	T10215	T10214	arg1Of	assays,These
R8826	T10215	T10217	arg1Of	assays,allowed
R8827	T10217	T10216	arg1Of	allowed,also
R8828	T10218	T10217	arg2Of	us,allowed
R8829	T10218	T10220	arg1Of	us,determine
R8830	T10220	T10217	arg3Of	determine,allowed
R8831	T10220	T10219	arg1Of	determine,to
R8832	T10221	T10220	arg2Of	what,determine
R8833	T10223	T10221	arg1Of	subunits,what
R8834	T10223	T10222	arg1Of	subunits,NF-κB
R8835	T10223	T10224	arg1Of	subunits,were
R8836	T10223	T10225	arg2Of	subunits,activated
R8837	T10225	T10224	arg2Of	activated,were
R8838	T10227	T10225	arg1Of	dCGN,activated
R8839	T10227	T10226	arg2Of	dCGN,by
R8840	T10229	T10228	arg1Of	forms,Both
R8841	T10229	T10230	arg1Of	forms,(
R8842	T10229	T10236	arg1Of	forms,of
R8843	T10229	T10238	arg1Of	forms,induced
R8844	T10231	T10232	arg1Of	10,or
R8845	T10233	T10232	arg2Of	40,or
R8846	T10234	T10230	arg2Of	kDa,(
R8847	T10234	T10231	arg1Of	kDa,10
R8848	T10234	T10233	arg1Of	kDa,40
R8849	T10235	T10230	arg3Of	),(
R8850	T10237	T10236	arg2Of	dCGN,of
R8851	T10239	T10238	arg2Of	activation,induced
R8852	T10239	T10240	arg1Of	activation,of
R8853	T10242	T10243	arg1Of	p50,and
R8854	T10244	T10243	arg2Of	p65,and
R8855	T10245	T10240	arg2Of	subunits,of
R8856	T10245	T10241	arg1Of	subunits,the
R8857	T10245	T10242	arg1Of	subunits,p50
R8858	T10245	T10244	arg1Of	subunits,p65
R8859	T10245	T10246	arg1Of	subunits,of
R8860	T10247	T10246	arg2Of	NF-κB,of
R8861	T10250	T10248	arg1Of	factor,This
R8862	T10250	T10249	arg1Of	factor,nuclear
R8863	T10250	T10251	arg1Of	factor,was
R8864	T10250	T10252	arg1Of	factor,present
R8865	T10250	T10261	arg1Of	factor,increased
R8866	T10251	T10260	arg1Of	was,and
R8867	T10252	T10251	arg2Of	present,was
R8868	T10252	T10253	arg1Of	present,in
R8869	T10255	T10253	arg2Of	levels,in
R8870	T10255	T10254	arg1Of	levels,low
R8871	T10255	T10256	arg1Of	levels,in
R8872	T10259	T10256	arg2Of	nucleus,in
R8873	T10259	T10257	arg1Of	nucleus,the
R8874	T10259	T10258	arg1Of	nucleus,cell
R8875	T10260	T10262	arg1Of	and,considerably
R8876	T10260	T10263	arg1Of	and,after
R8877	T10261	T10260	arg2Of	increased,and
R8878	T10264	T10263	arg2Of	treatment,after
R8879	T10264	T10265	arg1Of	treatment,with
R8880	T10266	T10265	arg2Of	dCGN,with
R8881	T10268	T10267	arg1Of	blots,Western
R8882	T10268	T10269	arg1Of	blots,suggested
R8883	T10269	T10270	arg1Of	suggested,the
R8884	T10272	T10273	arg1Of	40,kDa
R8885	T10274	T10271	arg1Of	form,the
R8886	T10274	T10272	arg1Of	form,40
R8887	T10274	T10275	arg1Of	form,of
R8888	T10274	T10277	arg1Of	form,induced
R8889	T10276	T10275	arg2Of	dCGN,of
R8890	T10277	T10269	arg2Of	induced,suggested
R8891	T10280	T10277	arg2Of	activation,induced
R8892	T10280	T10278	arg1Of	activation,a
R8893	T10280	T10279	arg1Of	activation,stronger
R8894	T10280	T10281	arg1Of	activation,of
R8895	T10282	T10281	arg2Of	NF-κB,of
R8896	T10282	T10283	arg1Of	NF-κB,(
R8897	T10285	T10283	arg2Of	7C,(
R8898	T10285	T10284	arg1Of	7C,Fig.
R8899	T10286	T10283	arg3Of	),(
R8900	T10289	T10288	arg1Of	sentive,more
R8901	T10290	T10287	arg1Of	assay,A
R8902	T10290	T10289	arg1Of	assay,sentive
R8903	T10290	T10291	arg1Of	assay,for
R8904	T10290	T10295	arg1Of	assay,is
R8905	T10294	T10291	arg2Of	activation,for
R8906	T10294	T10292	arg1Of	activation,nuclear
R8907	T10294	T10293	arg1Of	activation,factor
R8908	T10297	T10295	arg2Of	cytometry,is
R8909	T10297	T10296	arg1Of	cytometry,flow
R8910	T10297	T10298	arg1Of	cytometry,of
R8911	T10299	T10298	arg2Of	nuclei,of
R8912	T10299	T10300	arg2Of	nuclei,stained
R8913	T10300	T10301	arg1Of	stained,with
R8914	T10303	T10301	arg2Of	antibodies,with
R8915	T10303	T10302	arg1Of	antibodies,specific
R8916	T10303	T10304	arg1Of	antibodies,for
R8917	T10307	T10304	arg2Of	factor,for
R8918	T10307	T10305	arg1Of	factor,the
R8919	T10307	T10306	arg1Of	factor,nuclear
R8920	T10307	T10308	arg1Of	factor,of
R8921	T10309	T10308	arg2Of	interest,of
R8922	T10310	T10312	arg1Of	In,with
R8923	T10311	T10310	arg2Of	agreement,In
R8924	T10315	T10310	arg3Of	data,In
R8925	T10315	T10313	arg1Of	data,the
R8926	T10315	T10314	arg1Of	data,previous
R8927	T10318	T10317	arg1Of	analysis,FACS
R8928	T10318	T10319	arg1Of	analysis,of
R8929	T10318	T10324	arg1Of	analysis,showed
R8930	T10320	T10319	arg2Of	nuclei,of
R8931	T10320	T10321	arg1Of	nuclei,from
R8932	T10323	T10321	arg2Of	cells,from
R8933	T10323	T10322	arg1Of	cells,THP-1
R8934	T10324	T10310	arg1Of	showed,In
R8935	T10324	T10316	arg1Of	showed,","
R8936	T10326	T10327	arg1Of	there,was
R8937	T10327	T10324	arg2Of	was,showed
R8938	T10327	T10325	arg1Of	was,that
R8939	T10330	T10327	arg2Of	level,was
R8940	T10330	T10328	arg1Of	level,a
R8941	T10330	T10329	arg1Of	level,basal
R8942	T10330	T10331	arg1Of	level,of
R8943	T10333	T10331	arg2Of	NF-κB,of
R8944	T10333	T10332	arg1Of	NF-κB,nuclear
R8945	T10333	T10334	arg1Of	NF-κB,(
R8946	T10336	T10334	arg2Of	7D,(
R8947	T10336	T10335	arg1Of	7D,Fig.
R8948	T10337	T10334	arg3Of	),(
R8949	T10341	T10340	arg1Of	forms,both
R8950	T10341	T10342	arg1Of	forms,(
R8951	T10341	T10348	arg1Of	forms,of
R8952	T10341	T10350	arg1Of	forms,induced
R8953	T10343	T10344	arg1Of	10,or
R8954	T10345	T10344	arg2Of	40,or
R8955	T10346	T10342	arg2Of	kDa,(
R8956	T10346	T10343	arg1Of	kDa,10
R8957	T10346	T10345	arg1Of	kDa,40
R8958	T10347	T10342	arg3Of	),(
R8959	T10349	T10348	arg2Of	dCGN,of
R8960	T10350	T10338	arg1Of	induced,Again
R8961	T10350	T10339	arg1Of	induced,","
R8962	T10352	T10350	arg2Of	increase,induced
R8963	T10352	T10351	arg1Of	increase,an
R8964	T10352	T10353	arg1Of	increase,of
R8965	T10355	T10356	arg1Of	p50,and
R8966	T10357	T10356	arg2Of	p65,and
R8967	T10358	T10353	arg2Of	subunits,of
R8968	T10358	T10354	arg1Of	subunits,the
R8969	T10358	T10355	arg1Of	subunits,p50
R8970	T10358	T10357	arg1Of	subunits,p65
R8971	T10358	T10359	arg1Of	subunits,of
R8972	T10358	T10361	arg1Of	subunits,in
R8973	T10360	T10359	arg2Of	NF-κB,of
R8974	T10363	T10361	arg2Of	nucleus,in
R8975	T10363	T10362	arg1Of	nucleus,the
R8976	T10363	T10364	arg1Of	nucleus,of
R8977	T10366	T10364	arg2Of	cells,of
R8978	T10366	T10365	arg1Of	cells,these
R8979	T10371	T10367	arg1Of	CGN,The
R8980	T10371	T10368	arg1Of	CGN,40
R8981	T10371	T10369	arg1Of	CGN,kDa
R8982	T10371	T10370	arg2Of	CGN,degraded
R8983	T10371	T10372	arg1Of	CGN,gave
R8984	T10375	T10372	arg2Of	increase,gave
R8985	T10375	T10373	arg1Of	increase,a
R8986	T10375	T10374	arg1Of	increase,stronger
R8987	T10375	T10376	arg1Of	increase,of
R8988	T10377	T10376	arg2Of	NF-κB,of
R8989	T10377	T10378	arg1Of	NF-κB,(
R8990	T10380	T10378	arg2Of	7D,(
R8991	T10380	T10379	arg1Of	7D,Fig.
R8992	T10381	T10378	arg3Of	),(
R8993	T10383	T10382	arg1Of	data,These
R8994	T10383	T10385	arg1Of	data,suggest
R8995	T10385	T10384	arg1Of	suggest,strongly
R8996	T10389	T10387	arg1Of	p50/p65,the
R8997	T10389	T10388	arg1Of	p50/p65,heterodimer
R8998	T10389	T10390	arg1Of	p50/p65,is
R8999	T10390	T10385	arg2Of	is,suggest
R9000	T10390	T10386	arg1Of	is,that
R9001	T10393	T10390	arg2Of	isoform,is
R9002	T10393	T10391	arg1Of	isoform,the
R9003	T10393	T10392	arg1Of	isoform,NF-κB
R9004	T10393	T10394	arg2Of	isoform,activated
R9005	T10397	T10394	arg1Of	CGN,activated
R9006	T10397	T10395	arg2Of	CGN,by
R9007	T10397	T10396	arg2Of	CGN,degraded
R9008	T10397	T10398	arg1Of	CGN,in
R9009	T10399	T10398	arg2Of	monocytes,in
R9010	T10401	T10400	arg2Of	addition,In
R9011	T10403	T10404	arg1Of	degradation,of
R9012	T10403	T10408	arg1Of	degradation,was
R9013	T10403	T10410	arg2Of	degradation,observed
R9014	T10407	T10404	arg2Of	IκBα,of
R9015	T10407	T10405	arg1Of	IκBα,the
R9016	T10407	T10406	arg1Of	IκBα,inhibitor
R9017	T10410	T10400	arg1Of	observed,In
R9018	T10410	T10402	arg1Of	observed,","
R9019	T10410	T10408	arg2Of	observed,was
R9020	T10410	T10409	arg1Of	observed,also
R9021	T10410	T10411	arg1Of	observed,in
R9022	T10412	T10411	arg2Of	cells,in
R9023	T10412	T10413	arg2Of	cells,treated
R9024	T10413	T10414	arg1Of	treated,with
R9025	T10415	T10414	arg2Of	dCGN,with
R9026	T10415	T10416	arg1Of	dCGN,(
R9027	T10418	T10416	arg2Of	7B,(
R9028	T10418	T10417	arg1Of	7B,Fig.
R9029	T10419	T10416	arg3Of	),(
R9030	T10423	T10420	arg1Of	degradation,No
R9031	T10423	T10421	arg1Of	degradation,significant
R9032	T10423	T10422	arg1Of	degradation,IκBα
R9033	T10423	T10424	arg1Of	degradation,was
R9034	T10423	T10425	arg2Of	degradation,detected
R9035	T10425	T10424	arg2Of	detected,was
R9036	T10425	T10426	arg1Of	detected,within
R9037	T10425	T10433	arg1Of	detected,but
R9038	T10428	T10426	arg2Of	hours,within
R9039	T10428	T10427	arg1Of	hours,two
R9040	T10428	T10429	arg1Of	hours,of
R9041	T10431	T10429	arg2Of	treatment,of
R9042	T10431	T10430	arg1Of	treatment,dCGN
R9043	T10433	T10432	arg1Of	but,","
R9044	T10434	T10435	arg1Of	IκBα,was
R9045	T10434	T10437	arg2Of	IκBα,degraded
R9046	T10437	T10433	arg2Of	degraded,but
R9047	T10437	T10435	arg2Of	degraded,was
R9048	T10437	T10436	arg1Of	degraded,markedly
R9049	T10440	T10437	arg1Of	hours,degraded
R9050	T10440	T10438	arg2Of	hours,by
R9051	T10440	T10439	arg1Of	hours,four
R9052	T10440	T10441	arg1Of	hours,of
R9053	T10443	T10441	arg2Of	treatment,of
R9054	T10443	T10442	arg1Of	treatment,dCGN
R9055	T10443	T10444	arg1Of	treatment,(
R9056	T10446	T10444	arg2Of	7B,(
R9057	T10446	T10445	arg1Of	7B,Fig.
R9058	T10447	T10444	arg3Of	),(
R9059	T10448	T10449	arg1Of	We,focused
R9060	T10449	T10450	arg1Of	focused,on
R9061	T10449	T10453	arg1Of	focused,","
R9062	T10449	T10454	arg1Of	focused,since
R9063	T10452	T10450	arg2Of	subunit,on
R9064	T10452	T10451	arg1Of	subunit,IκBα
R9065	T10455	T10456	arg1Of	it,masks
R9066	T10456	T10463	arg1Of	masks,","
R9067	T10460	T10456	arg2Of	sequence,masks
R9068	T10460	T10457	arg1Of	sequence,the
R9069	T10460	T10458	arg1Of	sequence,nuclear
R9070	T10460	T10459	arg1Of	sequence,localisation
R9071	T10460	T10461	arg1Of	sequence,of
R9072	T10462	T10461	arg2Of	p65,of
R9073	T10463	T10454	arg2Of	",",since
R9074	T10464	T10465	arg1Of	it,is
R9075	T10465	T10463	arg2Of	is,","
R9076	T10468	T10467	arg1Of	rapidly,most
R9077	T10469	T10468	arg1Of	degraded,rapidly
R9078	T10470	T10466	arg1Of	subunit,the
R9079	T10470	T10469	arg1Of	subunit,degraded
R9080	T10470	T10471	arg1Of	subunit,and
R9081	T10471	T10465	arg2Of	and,is
R9082	T10474	T10473	arg1Of	studied,most
R9083	T10475	T10471	arg2Of	one,and
R9084	T10475	T10472	arg1Of	one,the
R9085	T10475	T10474	arg1Of	one,studied
R14952	T17543	T17542	arg2Of	CGN,Degraded
R14953	T17543	T17544	arg1Of	CGN,activated
R14954	T17547	T17544	arg2Of	pathway,activated
R14955	T17547	T17545	arg1Of	pathway,the
R14956	T17547	T17546	arg1Of	pathway,NF-kB
R14957	T17547	T17548	arg1Of	pathway,in
R14958	T17549	T17548	arg2Of	monocytes,in
R14959	T17553	T17552	arg1Of	cells,THP-1
R14960	T17553	T17554	arg1Of	cells,were
R14961	T17553	T17555	arg2Of	cells,transfected
R14962	T17555	T17554	arg2Of	transfected,were
R14963	T17555	T17556	arg1Of	transfected,with
R14964	T17560	T17556	arg2Of	plasmid,with
R14965	T17560	T17557	arg1Of	plasmid,a
R14966	T17560	T17558	arg1Of	plasmid,NF-κB
R14967	T17560	T17559	arg1Of	plasmid,reporter
R14968	T17561	T17551	arg1Of	driving,:
R14969	T17561	T17554	modOf	driving,were
R14970	T17562	T17550	arg1Of	expression,A
R14971	T17562	T17561	arg1Of	expression,driving
R14972	T17562	T17563	arg1Of	expression,of
R14973	T17564	T17563	arg2Of	luciferase,of
R14974	T17565	T17566	arg1Of	Cells,were
R14975	T17565	T17568	arg2Of	Cells,treated
R14976	T17568	T17566	arg2Of	treated,were
R14977	T17568	T17567	arg1Of	treated,then
R14978	T17568	T17569	arg1Of	treated,with
R14979	T17571	T17569	arg2Of	concentrations,with
R14980	T17571	T17570	arg1Of	concentrations,various
R14981	T17571	T17572	arg1Of	concentrations,of
R14982	T17574	T17573	arg1Of	kDa,10
R14983	T17574	T17575	arg1Of	kDa,(
R14984	T17574	T17579	arg1Of	kDa,or
R14985	T17576	T17575	arg2Of	triangles,(
R14986	T17577	T17575	arg3Of	),(
R14987	T17579	T17572	arg2Of	or,of
R14988	T17579	T17578	arg1Of	or,","
R14989	T17582	T17579	arg2Of	dCGN,or
R14990	T17582	T17580	arg1Of	dCGN,40
R14991	T17582	T17581	arg1Of	dCGN,kDa
R14992	T17582	T17583	arg1Of	dCGN,(
R14993	T17584	T17583	arg2Of	squares,(
R14994	T17585	T17583	arg3Of	),(
R14995	T17586	T17587	arg1Of	B,:
R14996	T17589	T17588	arg1Of	cells,THP-1
R14997	T17589	T17590	arg2Of	cells,treated
R14998	T17589	T17613	arg1Of	cells,were
R14999	T17589	T17614	arg2Of	cells,lysed
R15000	T17590	T17591	arg1Of	treated,with
R15001	T17590	T17603	arg1Of	treated,with
R15002	T17591	T17602	arg1Of	with,or
R15003	T17593	T17591	arg2Of	mg/ml,with
R15004	T17593	T17592	arg1Of	mg/ml,1
R15005	T17593	T17594	arg1Of	mg/ml,of
R15006	T17597	T17594	arg2Of	dCGN,of
R15007	T17597	T17595	arg1Of	dCGN,10
R15008	T17597	T17596	arg1Of	dCGN,kDa
R15009	T17597	T17598	arg1Of	dCGN,(
R15010	T17599	T17598	arg2Of	C10,(
R15011	T17600	T17598	arg3Of	),(
R15012	T17602	T17601	arg1Of	or,","
R15013	T17603	T17602	arg2Of	with,or
R15014	T17605	T17603	arg2Of	mg/ml,with
R15015	T17605	T17604	arg1Of	mg/ml,1
R15016	T17605	T17606	arg1Of	mg/ml,of
R15017	T17609	T17606	arg2Of	dCGN,of
R15018	T17609	T17607	arg1Of	dCGN,40
R15019	T17609	T17608	arg1Of	dCGN,kDa
R15020	T17609	T17610	arg1Of	dCGN,(
R15021	T17611	T17610	arg2Of	C40,(
R15022	T17612	T17610	arg3Of	),(
R15023	T17614	T17587	arg2Of	lysed,:
R15024	T17614	T17613	arg2Of	lysed,were
R15025	T17614	T17615	arg1Of	lysed,after
R15026	T17617	T17615	arg2Of	periods,after
R15027	T17617	T17616	arg1Of	periods,various
R15028	T17617	T17618	arg1Of	periods,of
R15029	T17619	T17618	arg2Of	time,of
R15030	T17620	T17621	arg1Of	Proteins,in
R15031	T17620	T17624	arg1Of	Proteins,were
R15032	T17620	T17625	arg2Of	Proteins,resolved
R15033	T17623	T17621	arg2Of	extracts,in
R15034	T17623	T17622	arg1Of	extracts,cell
R15035	T17625	T17624	arg2Of	resolved,were
R15036	T17625	T17626	arg1Of	resolved,by
R15037	T17625	T17632	arg1Of	resolved,for
R15038	T17627	T17628	arg1Of	SDS-PAGE,and
R15039	T17628	T17626	arg2Of	and,by
R15040	T17630	T17629	arg1Of	Western,then
R15041	T17631	T17628	arg2Of	blotted,and
R15042	T17631	T17630	arg1Of	blotted,Western
R15043	T17633	T17634	arg1Of	IκBα,or
R15044	T17634	T17632	arg2Of	or,for
R15045	T17634	T17636	arg1Of	or,as
R15046	T17635	T17634	arg2Of	α−tubulin,or
R15047	T17637	T17636	arg2Of	loading,as
R15048	T17638	T17637	arg2Of	control,loading
R15049	T17639	T17640	arg1Of	C,:
R15050	T17642	T17641	arg2Of	carrageenans,Degraded
R15051	T17642	T17643	arg1Of	carrageenans,(
R15052	T17642	T17646	arg1Of	carrageenans,induced
R15053	T17644	T17643	arg2Of	dCGN,(
R15054	T17645	T17643	arg3Of	),(
R15055	T17647	T17646	arg2Of	activation,induced
R15056	T17647	T17648	arg1Of	activation,of
R15057	T17649	T17648	arg2Of	NF-κB,of
R15058	T17651	T17650	arg1Of	cells,THP-1
R15059	T17651	T17652	arg1Of	cells,were
R15060	T17651	T17653	arg2Of	cells,treated
R15061	T17653	T17652	arg2Of	treated,were
R15062	T17653	T17654	arg1Of	treated,with
R15063	T17653	T17661	arg1Of	treated,with
R15064	T17653	T17673	arg1Of	treated,with
R15065	T17654	T17660	arg1Of	with,or
R15066	T17655	T17654	arg2Of	nothing,with
R15067	T17655	T17656	arg1Of	nothing,(
R15068	T17657	T17656	arg2Of	control,(
R15069	T17658	T17656	arg3Of	),(
R15070	T17660	T17659	arg1Of	or,","
R15071	T17660	T17672	arg1Of	or,or
R15072	T17661	T17660	arg2Of	with,or
R15073	T17663	T17661	arg2Of	mg/ml,with
R15074	T17663	T17662	arg1Of	mg/ml,1
R15075	T17663	T17664	arg1Of	mg/ml,of
R15076	T17667	T17664	arg2Of	dCGN,of
R15077	T17667	T17665	arg1Of	dCGN,10
R15078	T17667	T17666	arg1Of	dCGN,kDa
R15079	T17667	T17668	arg1Of	dCGN,(
R15080	T17669	T17668	arg2Of	C10,(
R15081	T17670	T17668	arg3Of	),(
R15082	T17672	T17671	arg1Of	or,","
R15083	T17673	T17672	arg2Of	with,or
R15084	T17675	T17673	arg2Of	mg/ml,with
R15085	T17675	T17674	arg1Of	mg/ml,1
R15086	T17679	T17676	arg1Of	dCGN,of
R15087	T17679	T17677	arg1Of	dCGN,40
R15088	T17679	T17678	arg1Of	dCGN,kDa
R15089	T17679	T17680	arg1Of	dCGN,(
R15090	T17679	T17683	arg1Of	dCGN,for
R15091	T17679	T17686	arg1Of	dCGN,at
R15092	T17679	T17689	arg1Of	dCGN,were
R15093	T17679	T17690	arg2Of	dCGN,isolated
R15094	T17679	T17692	arg2Of	dCGN,lysed
R15095	T17681	T17680	arg2Of	C40,(
R15096	T17682	T17680	arg3Of	),(
R15097	T17685	T17683	arg2Of	minutes,for
R15098	T17685	T17684	arg1Of	minutes,30
R15099	T17688	T17686	arg2Of	Nuclei,at
R15100	T17688	T17687	arg1Of	Nuclei,37°C.
R15101	T17690	T17691	arg1Of	isolated,and
R15102	T17691	T17652	modOf	and,were
R15103	T17691	T17689	arg2Of	and,were
R15104	T17692	T17691	arg2Of	lysed,and
R15105	T17693	T17694	arg1Of	Proteins,in
R15106	T17693	T17697	arg1Of	Proteins,were
R15107	T17693	T17698	arg2Of	Proteins,resolved
R15108	T17696	T17694	arg2Of	extracts,in
R15109	T17696	T17695	arg1Of	extracts,nuclear
R15110	T17698	T17697	arg2Of	resolved,were
R15111	T17698	T17699	arg1Of	resolved,by
R15112	T17698	T17705	arg1Of	resolved,for
R15113	T17700	T17701	arg1Of	SDS-PAGE,and
R15114	T17701	T17699	arg2Of	and,by
R15115	T17703	T17702	arg1Of	Western,then
R15116	T17704	T17701	arg2Of	blotted,and
R15117	T17704	T17703	arg1Of	blotted,Western
R15118	T17708	T17706	arg1Of	subunit,NF-κB
R15119	T17708	T17707	arg1Of	subunit,p50
R15120	T17708	T17709	arg1Of	subunit,(
R15121	T17708	T17712	arg1Of	subunit,or
R15122	T17710	T17709	arg2Of	p50,(
R15123	T17711	T17709	arg3Of	),(
R15124	T17712	T17705	arg2Of	or,for
R15125	T17715	T17712	arg2Of	subunit,or
R15126	T17715	T17713	arg1Of	subunit,NF-κB
R15127	T17715	T17714	arg1Of	subunit,p65
R15128	T17715	T17716	arg1Of	subunit,(
R15129	T17717	T17716	arg2Of	p65,(
R15130	T17718	T17716	arg3Of	),(
R15131	T17720	T17719	arg1Of	panels,Lower
R15132	T17720	T17721	arg1Of	panels,show
R15133	T17723	T17721	arg2Of	blots,show
R15134	T17723	T17722	arg1Of	blots,Western
R15135	T17723	T17724	arg1Of	blots,of
R15136	T17726	T17724	arg2Of	ERK,of
R15137	T17726	T17725	arg1Of	ERK,nuclear
R15138	T17726	T17727	arg1Of	ERK,revealing
R15139	T17727	T17732	arg1Of	revealing,in
R15140	T17729	T17727	arg2Of	amount,revealing
R15141	T17729	T17728	arg1Of	amount,equivalent
R15142	T17729	T17730	arg1Of	amount,of
R15143	T17731	T17730	arg2Of	protein,of
R15144	T17734	T17732	arg2Of	sample,in
R15145	T17734	T17733	arg1Of	sample,each
R15146	T17735	T17736	arg1Of	Data,are
R15147	T17735	T17737	arg1Of	Data,representative
R15148	T17737	T17736	arg2Of	representative,are
R15149	T17737	T17738	arg1Of	representative,of
R15150	T17741	T17738	arg2Of	experiments,of
R15151	T17741	T17739	arg1Of	experiments,three
R15152	T17741	T17740	arg1Of	experiments,separate
R15153	T17742	T17743	arg1Of	D,:
R15154	T17745	T17744	arg2Of	carrageenan,Degraded
R15155	T17745	T17746	arg1Of	carrageenan,(
R15156	T17745	T17749	arg1Of	carrageenan,induced
R15157	T17747	T17746	arg2Of	dCGN,(
R15158	T17748	T17746	arg3Of	),(
R15159	T17750	T17749	arg2Of	activation,induced
R15160	T17750	T17751	arg1Of	activation,of
R15161	T17752	T17751	arg2Of	NF-κB,of
R15162	T17753	T17754	arg2Of	Nuclei,isolated
R15163	T17753	T17758	arg1Of	Nuclei,were
R15164	T17753	T17759	arg1Of	Nuclei,fluorescence-stained
R15165	T17754	T17755	arg1Of	isolated,from
R15166	T17757	T17755	arg2Of	cells,from
R15167	T17757	T17756	arg1Of	cells,THP-1
R15168	T17758	T17768	arg1Of	were,before
R15169	T17758	T17774	arg1Of	were,after
R15170	T17759	T17758	arg2Of	fluorescence-stained,were
R15171	T17759	T17760	arg1Of	fluorescence-stained,for
R15172	T17763	T17761	arg1Of	subunit,NF-κB
R15173	T17763	T17762	arg1Of	subunit,p50
R15174	T17763	T17764	arg1Of	subunit,or
R15175	T17764	T17760	arg2Of	or,for
R15176	T17767	T17764	arg2Of	subunit,or
R15177	T17767	T17765	arg1Of	subunit,NF-κB
R15178	T17767	T17766	arg1Of	subunit,p65
R15179	T17768	T17769	arg1Of	before,(
R15180	T17768	T17773	arg1Of	before,or
R15181	T17771	T17769	arg2Of	area,(
R15182	T17771	T17770	arg2Of	area,filled
R15183	T17772	T17769	arg3Of	),(
R15184	T17774	T17773	arg2Of	after,or
R15185	T17775	T17776	arg1Of	cells,were
R15186	T17775	T17777	arg2Of	cells,treated
R15187	T17777	T17776	arg2Of	treated,were
R15188	T17777	T17778	arg1Of	treated,with
R15189	T17777	T17790	arg1Of	treated,with
R15190	T17778	T17789	arg1Of	with,or
R15191	T17780	T17778	arg2Of	mg/ml,with
R15192	T17780	T17779	arg1Of	mg/ml,1
R15193	T17780	T17781	arg1Of	mg/ml,of
R15194	T17784	T17781	arg2Of	dCGN,of
R15195	T17784	T17782	arg1Of	dCGN,10
R15196	T17784	T17783	arg1Of	dCGN,kDa
R15197	T17784	T17785	arg1Of	dCGN,(
R15198	T17786	T17785	arg2Of	C10,(
R15199	T17787	T17785	arg3Of	),(
R15200	T17789	T17788	arg1Of	or,","
R15201	T17790	T17789	arg2Of	with,or
R15202	T17792	T17790	arg2Of	mg/ml,with
R15203	T17792	T17791	arg1Of	mg/ml,1
R15204	T17796	T17793	arg1Of	dCGN,of
R15205	T17796	T17794	arg1Of	dCGN,40
R15206	T17796	T17795	arg1Of	dCGN,kDa
R15207	T17796	T17797	arg1Of	dCGN,(
R15208	T17796	T17800	arg1Of	dCGN,for
R15209	T17796	T17803	arg1Of	dCGN,at
R15210	T17796	T17807	arg1Of	dCGN,corresponds
R15211	T17798	T17797	arg2Of	C40,(
R15212	T17799	T17797	arg3Of	),(
R15213	T17802	T17800	arg2Of	minutes,for
R15214	T17802	T17801	arg1Of	minutes,30
R15215	T17805	T17804	arg1Of	Dashed,37°C.
R15216	T17806	T17803	arg2Of	line,at
R15217	T17806	T17805	arg1Of	line,Dashed
R15218	T17807	T17768	arg2Of	corresponds,before
R15219	T17807	T17774	arg2Of	corresponds,after
R15220	T17807	T17776	modOf	corresponds,were
R15221	T17807	T17808	arg1Of	corresponds,to
R15222	T17809	T17808	arg2Of	nuclei,to
R15223	T17809	T17810	arg2Of	nuclei,stained
R15224	T17810	T17812	arg1Of	stained,with
R15225	T17812	T17811	arg1Of	with,only
R15226	T17815	T17812	arg2Of	antibody,with
R15227	T17815	T17813	arg1Of	antibody,secondary
R15228	T17815	T17814	arg1Of	antibody,fluorescence
R15229	T17817	T17816	arg1Of	intensity,Fluorescence
R15230	T17817	T17818	arg1Of	intensity,was
R15231	T17817	T17819	arg2Of	intensity,analyzed
R15232	T17819	T17818	arg2Of	analyzed,was
R15233	T17819	T17823	arg1Of	analyzed,as
R15234	T17822	T17819	arg1Of	cytometry,analyzed
R15235	T17822	T17820	arg2Of	cytometry,by
R15236	T17822	T17821	arg1Of	cytometry,flow
R15237	T17824	T17823	arg2Of	described,as

bionlp-st-ge-2016-coref

Id	Subject	Object	Predicate	Lexical cue
T10476	2062-2064	Anaphor	denotes	it
T10477	2042-2046	Antecedent	denotes	IκBα
T10478	2113-2115	Anaphor	denotes	it
R9086	T10476	T10477	boundBy	it,IκBα
R9087	T10478	T10477	boundBy	it,IκBα

bionlp-st-ge-2016-spacy-parsed

Id	Subject	Object	Predicate	Lexical cue
T10499	0-8	JJ	denotes	Degraded
T10500	9-12	NNP	denotes	CGN
T10501	13-19	NNP	denotes	Induce
T10502	20-23	NNP	denotes	IκB
T10503	24-35	NNP	denotes	Degradation
T10504	36-39	CC	denotes	and
T10505	40-45	NNP	denotes	NF-κB
T10506	46-56	NNP	denotes	Activation
T10507	57-60	NNP	denotes	The
T10508	61-71	NN	denotes	expression
T10509	72-74	IN	denotes	of
T10510	75-80	NNS	denotes	genes
T10511	81-89	VBG	denotes	encoding
T10512	90-93	IN	denotes	for
T10513	94-100	NNP	denotes	ICAM-1
T10514	101-104	CC	denotes	and
T10515	105-110	NNP	denotes	TNF-α
T10516	111-113	VBZ	denotes	is
T10517	114-124	VBN	denotes	controlled
T10518	125-127	IN	denotes	by
T10519	128-131	DT	denotes	the
T10520	132-139	JJ	denotes	nuclear
T10521	140-146	NN	denotes	factor
T10522	147-152	NN	denotes	NF-κB
T10523	152-153	.	denotes	.
T10524	154-167	JJ	denotes	Site-specific
T10525	168-183	NN	denotes	phosphorylation
T10526	184-186	IN	denotes	of
T10527	187-190	DT	denotes	the
T10528	191-200	NN	denotes	inhibitor
T10529	201-204	NNP	denotes	IκB
T10530	205-210	VBZ	denotes	leads
T10531	211-213	TO	denotes	to
T10532	214-217	PRP$	denotes	its
T10533	218-229	NN	denotes	degradation
T10534	230-232	IN	denotes	by
T10535	233-243	JJ	denotes	proteasome
T10536	244-247	CC	denotes	and
T10537	248-250	TO	denotes	to
T10538	251-252	DT	denotes	a
T10539	253-266	JJ	denotes	consequential
T10540	267-277	NN	denotes	activation
T10541	278-280	IN	denotes	of
T10542	281-284	DT	denotes	the
T10543	285-290	NNP	denotes	NF-κB
T10544	291-298	NN	denotes	pathway
T10545	298-299	.	denotes	.
T10546	300-305	VBG	denotes	Using
T10547	306-307	DT	denotes	a
T10548	308-316	NN	denotes	reporter
T10549	317-324	NN	denotes	plasmid
T10550	325-328	IN	denotes	for
T10551	329-334	JJ	denotes	NF-κB
T10552	335-345	NN	denotes	activation
T10553	345-346	,	denotes	,
T10554	347-349	PRP	denotes	it
T10555	350-353	VBD	denotes	was
T10556	354-363	VBN	denotes	confirmed
T10557	364-368	IN	denotes	that
T10558	369-373	NNP	denotes	dCGN
T10559	374-381	VBD	denotes	induced
T10560	382-383	DT	denotes	a
T10561	384-390	JJ	denotes	strong
T10562	391-401	NN	denotes	activation
T10563	402-404	IN	denotes	of
T10564	405-410	NNP	denotes	NF-κB
T10565	410-411	,	denotes	,
T10566	412-414	IN	denotes	as
T10567	415-424	VBN	denotes	reflected
T10568	425-427	IN	denotes	by
T10569	428-430	DT	denotes	an
T10570	431-439	NN	denotes	increase
T10571	440-442	IN	denotes	in
T10572	443-453	NN	denotes	luciferase
T10573	454-462	NN	denotes	activity
T10574	463-464	-LRB-	denotes	(
T10575	464-468	NNP	denotes	Fig.
T10576	469-471	NN	denotes	7A
T10577	471-472	-RRB-	denotes	)
T10578	472-473	.	denotes	.
T10579	474-478	DT	denotes	Both
T10580	479-484	NNS	denotes	forms
T10581	485-487	IN	denotes	of
T10582	488-492	NNP	denotes	dCGN
T10583	493-497	VBD	denotes	used
T10584	498-505	JJ	denotes	induced
T10585	506-511	NN	denotes	NF-κB
T10586	512-522	NN	denotes	activation
T10587	523-525	IN	denotes	in
T10588	526-527	DT	denotes	a
T10589	528-532	NN	denotes	dose
T10590	533-542	JJ	denotes	dependent
T10591	543-549	NN	denotes	manner
T10592	549-550	.	denotes	.
T10593	551-558	RB	denotes	However
T10594	558-559	,	denotes	,
T10595	560-563	DT	denotes	the
T10596	564-570	NN	denotes	effect
T10597	571-574	VBD	denotes	was
T10598	575-579	RBR	denotes	more
T10599	580-588	RB	denotes	strongly
T10600	589-596	VBN	denotes	induced
T10601	597-599	IN	denotes	by
T10602	600-603	DT	denotes	the
T10603	604-606	CD	denotes	40
T10604	607-610	NNP	denotes	kDa
T10605	611-615	NNP	denotes	dCGN
T10606	616-617	-LRB-	denotes	(
T10607	617-621	NNP	denotes	Fig.
T10608	622-624	NN	denotes	7A
T10609	624-625	-RRB-	denotes	)
T10610	625-626	.	denotes	.
T10611	627-632	DT	denotes	These
T10612	633-640	NNS	denotes	results
T10613	641-645	VBD	denotes	were
T10614	646-653	JJ	denotes	further
T10615	654-663	VBN	denotes	confirmed
T10616	664-666	IN	denotes	by
T10617	667-675	RB	denotes	directly
T10618	676-685	VBG	denotes	detecting
T10619	686-691	NN	denotes	NF-κB
T10620	692-694	IN	denotes	in
T10621	695-698	DT	denotes	the
T10622	699-703	NN	denotes	cell
T10623	704-711	NN	denotes	nucleus
T10624	712-714	IN	denotes	by
T10625	715-722	JJ	denotes	Western
T10626	723-731	VBG	denotes	blotting
T10627	732-733	-LRB-	denotes	(
T10628	733-737	NNP	denotes	Fig.
T10629	738-740	NNP	denotes	7C
T10630	740-741	-RRB-	denotes	)
T10631	742-745	CC	denotes	and
T10632	746-748	IN	denotes	by
T10633	749-753	NNP	denotes	FACS
T10634	754-755	-LRB-	denotes	(
T10635	755-759	NNP	denotes	Fig.
T10636	760-762	NNP	denotes	7D
T10637	762-763	-RRB-	denotes	)
T10638	763-764	.	denotes	.
T10639	765-770	DT	denotes	These
T10640	771-777	NNS	denotes	assays
T10641	778-782	RB	denotes	also
T10642	783-790	VBD	denotes	allowed
T10643	791-793	PRP	denotes	us
T10644	794-796	TO	denotes	to
T10645	797-806	VB	denotes	determine
T10646	807-811	WP	denotes	what
T10647	812-817	NNP	denotes	NF-κB
T10648	818-826	NNS	denotes	subunits
T10649	827-831	VBD	denotes	were
T10650	832-841	VBN	denotes	activated
T10651	842-844	IN	denotes	by
T10652	845-849	NNP	denotes	dCGN
T10653	849-850	.	denotes	.
T10654	851-855	DT	denotes	Both
T10655	856-861	NNS	denotes	forms
T10656	862-863	-LRB-	denotes	(
T10657	863-865	CD	denotes	10
T10658	866-868	CC	denotes	or
T10659	869-871	CD	denotes	40
T10660	872-875	NN	denotes	kDa
T10661	875-876	-RRB-	denotes	)
T10662	877-879	IN	denotes	of
T10663	880-884	NNP	denotes	dCGN
T10664	885-892	VBD	denotes	induced
T10665	893-903	NN	denotes	activation
T10666	904-906	IN	denotes	of
T10667	907-910	DT	denotes	the
T10668	911-914	CD	denotes	p50
T10669	915-918	CC	denotes	and
T10670	919-922	CD	denotes	p65
T10671	923-931	NNS	denotes	subunits
T10672	932-934	IN	denotes	of
T10673	935-940	NN	denotes	NF-κB
T10674	940-941	.	denotes	.
T10675	942-946	DT	denotes	This
T10676	947-954	JJ	denotes	nuclear
T10677	955-961	NN	denotes	factor
T10678	962-965	VBD	denotes	was
T10679	966-973	JJ	denotes	present
T10680	974-976	IN	denotes	in
T10681	977-980	JJ	denotes	low
T10682	981-987	NNS	denotes	levels
T10683	988-990	IN	denotes	in
T10684	991-994	DT	denotes	the
T10685	995-999	NN	denotes	cell
T10686	1000-1007	NN	denotes	nucleus
T10687	1008-1011	CC	denotes	and
T10688	1012-1021	VBD	denotes	increased
T10689	1022-1034	RB	denotes	considerably
T10690	1035-1040	IN	denotes	after
T10691	1041-1050	NN	denotes	treatment
T10692	1051-1055	IN	denotes	with
T10693	1056-1060	NNP	denotes	dCGN
T10694	1060-1061	.	denotes	.
T10695	1062-1069	JJ	denotes	Western
T10696	1070-1075	NNS	denotes	blots
T10697	1076-1085	VBD	denotes	suggested
T10698	1086-1089	DT	denotes	the
T10699	1090-1093	DT	denotes	the
T10700	1094-1096	CD	denotes	40
T10701	1097-1100	NNP	denotes	kDa
T10702	1101-1105	NN	denotes	form
T10703	1106-1108	IN	denotes	of
T10704	1109-1113	NNP	denotes	dCGN
T10705	1114-1121	VBD	denotes	induced
T10706	1122-1123	DT	denotes	a
T10707	1124-1132	JJR	denotes	stronger
T10708	1133-1143	NN	denotes	activation
T10709	1144-1146	IN	denotes	of
T10710	1147-1152	NNP	denotes	NF-κB
T10711	1153-1154	-LRB-	denotes	(
T10712	1154-1158	NNP	denotes	Fig.
T10713	1159-1161	NNP	denotes	7C
T10714	1161-1162	-RRB-	denotes	)
T10715	1162-1163	.	denotes	.
T10716	1164-1165	DT	denotes	A
T10717	1166-1170	JJR	denotes	more
T10718	1171-1178	JJ	denotes	sentive
T10719	1179-1184	NN	denotes	assay
T10720	1185-1188	IN	denotes	for
T10721	1189-1196	JJ	denotes	nuclear
T10722	1197-1203	NN	denotes	factor
T10723	1204-1214	NN	denotes	activation
T10724	1215-1217	VBZ	denotes	is
T10725	1218-1222	NN	denotes	flow
T10726	1223-1232	NN	denotes	cytometry
T10727	1233-1235	IN	denotes	of
T10728	1236-1242	JJ	denotes	nuclei
T10729	1243-1250	VBN	denotes	stained
T10730	1251-1255	IN	denotes	with
T10731	1256-1264	JJ	denotes	specific
T10732	1265-1275	NNS	denotes	antibodies
T10733	1276-1279	IN	denotes	for
T10734	1280-1283	DT	denotes	the
T10735	1284-1291	JJ	denotes	nuclear
T10736	1292-1298	NN	denotes	factor
T10737	1299-1301	IN	denotes	of
T10738	1302-1310	NN	denotes	interest
T10739	1310-1311	.	denotes	.
T10740	1312-1314	IN	denotes	In
T10741	1315-1324	NN	denotes	agreement
T10742	1325-1329	IN	denotes	with
T10743	1330-1333	DT	denotes	the
T10744	1334-1342	JJ	denotes	previous
T10745	1343-1347	NNS	denotes	data
T10746	1347-1348	,	denotes	,
T10747	1349-1353	NNP	denotes	FACS
T10748	1354-1362	NN	denotes	analysis
T10749	1363-1365	IN	denotes	of
T10750	1366-1372	NNS	denotes	nuclei
T10751	1373-1377	IN	denotes	from
T10752	1378-1383	CD	denotes	THP-1
T10753	1384-1389	NNS	denotes	cells
T10754	1390-1396	VBD	denotes	showed
T10755	1397-1401	IN	denotes	that
T10756	1402-1407	EX	denotes	there
T10757	1408-1411	VBD	denotes	was
T10758	1412-1413	DT	denotes	a
T10759	1414-1419	JJ	denotes	basal
T10760	1420-1425	NN	denotes	level
T10761	1426-1428	IN	denotes	of
T10762	1429-1436	JJ	denotes	nuclear
T10763	1437-1442	NNP	denotes	NF-κB
T10764	1443-1444	-LRB-	denotes	(
T10765	1444-1448	NNP	denotes	Fig.
T10766	1449-1451	NNP	denotes	7D
T10767	1451-1452	-RRB-	denotes	)
T10768	1452-1453	.	denotes	.
T10769	1454-1459	RB	denotes	Again
T10770	1459-1460	,	denotes	,
T10771	1461-1465	DT	denotes	both
T10772	1466-1471	NNS	denotes	forms
T10773	1472-1473	-LRB-	denotes	(
T10774	1473-1475	CD	denotes	10
T10775	1476-1478	CC	denotes	or
T10776	1479-1481	CD	denotes	40
T10777	1482-1485	NN	denotes	kDa
T10778	1485-1486	-RRB-	denotes	)
T10779	1487-1489	IN	denotes	of
T10780	1490-1494	NNP	denotes	dCGN
T10781	1495-1502	VBD	denotes	induced
T10782	1503-1505	DT	denotes	an
T10783	1506-1514	NN	denotes	increase
T10784	1515-1517	IN	denotes	of
T10785	1518-1521	DT	denotes	the
T10786	1522-1525	CD	denotes	p50
T10787	1526-1529	CC	denotes	and
T10788	1530-1533	CD	denotes	p65
T10789	1534-1542	NNS	denotes	subunits
T10790	1543-1545	IN	denotes	of
T10791	1546-1551	NN	denotes	NF-κB
T10792	1552-1554	IN	denotes	in
T10793	1555-1558	DT	denotes	the
T10794	1559-1566	NN	denotes	nucleus
T10795	1567-1569	IN	denotes	of
T10796	1570-1575	DT	denotes	these
T10797	1576-1581	NNS	denotes	cells
T10798	1581-1582	.	denotes	.
T10799	1583-1586	DT	denotes	The
T10800	1587-1589	CD	denotes	40
T10801	1590-1593	NN	denotes	kDa
T10802	1594-1602	JJ	denotes	degraded
T10803	1603-1606	NNP	denotes	CGN
T10804	1607-1611	VBD	denotes	gave
T10805	1612-1613	DT	denotes	a
T10806	1614-1622	JJR	denotes	stronger
T10807	1623-1631	NN	denotes	increase
T10808	1632-1634	IN	denotes	of
T10809	1635-1640	NNP	denotes	NF-κB
T10810	1641-1642	-LRB-	denotes	(
T10811	1642-1646	NNP	denotes	Fig.
T10812	1647-1649	NNP	denotes	7D
T10813	1649-1650	-RRB-	denotes	)
T10814	1650-1651	.	denotes	.
T10815	1652-1657	DT	denotes	These
T10816	1658-1662	NNS	denotes	data
T10817	1663-1671	RB	denotes	strongly
T10818	1672-1679	VBP	denotes	suggest
T10819	1680-1684	IN	denotes	that
T10820	1685-1688	DT	denotes	the
T10821	1689-1700	NN	denotes	heterodimer
T10822	1701-1708	CD	denotes	p50/p65
T10823	1709-1711	VBZ	denotes	is
T10824	1712-1715	DT	denotes	the
T10825	1716-1721	JJ	denotes	NF-κB
T10826	1722-1729	NN	denotes	isoform
T10827	1730-1739	VBN	denotes	activated
T10828	1740-1742	IN	denotes	by
T10829	1743-1751	JJ	denotes	degraded
T10830	1752-1755	NNP	denotes	CGN
T10831	1756-1758	IN	denotes	in
T10832	1759-1768	NNS	denotes	monocytes
T10833	1768-1769	.	denotes	.
T10834	1770-1772	IN	denotes	In
T10835	1773-1781	NN	denotes	addition
T10836	1781-1782	,	denotes	,
T10837	1783-1794	NN	denotes	degradation
T10838	1795-1797	IN	denotes	of
T10839	1798-1801	DT	denotes	the
T10840	1802-1811	NN	denotes	inhibitor
T10841	1812-1816	NNP	denotes	IκBα
T10842	1817-1820	VBD	denotes	was
T10843	1821-1825	RB	denotes	also
T10844	1826-1834	VBN	denotes	observed
T10845	1835-1837	IN	denotes	in
T10846	1838-1843	NNS	denotes	cells
T10847	1844-1851	VBN	denotes	treated
T10848	1852-1856	IN	denotes	with
T10849	1857-1861	NNP	denotes	dCGN
T10850	1862-1863	-LRB-	denotes	(
T10851	1863-1867	NNP	denotes	Fig.
T10852	1868-1870	NN	denotes	7B
T10853	1870-1871	-RRB-	denotes	)
T10854	1871-1872	.	denotes	.
T10855	1873-1875	DT	denotes	No
T10856	1876-1887	JJ	denotes	significant
T10857	1888-1892	NNP	denotes	IκBα
T10858	1893-1904	NN	denotes	degradation
T10859	1905-1908	VBD	denotes	was
T10860	1909-1917	VBN	denotes	detected
T10861	1918-1924	IN	denotes	within
T10862	1925-1928	CD	denotes	two
T10863	1929-1934	NNS	denotes	hours
T10864	1935-1937	IN	denotes	of
T10865	1938-1942	NNP	denotes	dCGN
T10866	1943-1952	NN	denotes	treatment
T10867	1952-1953	,	denotes	,
T10868	1954-1957	CC	denotes	but
T10869	1958-1962	NNP	denotes	IκBα
T10870	1963-1966	VBD	denotes	was
T10871	1967-1975	RB	denotes	markedly
T10872	1976-1984	JJ	denotes	degraded
T10873	1985-1987	IN	denotes	by
T10874	1988-1992	CD	denotes	four
T10875	1993-1998	NNS	denotes	hours
T10876	1999-2001	IN	denotes	of
T10877	2002-2006	NNP	denotes	dCGN
T10878	2007-2016	NN	denotes	treatment
T10879	2017-2018	-LRB-	denotes	(
T10880	2018-2022	NNP	denotes	Fig.
T10881	2023-2025	NN	denotes	7B
T10882	2025-2026	-RRB-	denotes	)
T10883	2026-2027	.	denotes	.
T10884	2028-2030	PRP	denotes	We
T10885	2031-2038	VBD	denotes	focused
T10886	2039-2041	IN	denotes	on
T10887	2042-2046	NNP	denotes	IκBα
T10888	2047-2054	NN	denotes	subunit
T10889	2054-2055	,	denotes	,
T10890	2056-2061	IN	denotes	since
T10891	2062-2064	PRP	denotes	it
T10892	2065-2070	NNS	denotes	masks
T10893	2071-2074	DT	denotes	the
T10894	2075-2082	JJ	denotes	nuclear
T10895	2083-2095	NN	denotes	localisation
T10896	2096-2104	NN	denotes	sequence
T10897	2105-2107	IN	denotes	of
T10898	2108-2111	NNS	denotes	p65
T10899	2111-2112	,	denotes	,
T10900	2113-2115	PRP	denotes	it
T10901	2116-2118	VBZ	denotes	is
T10902	2119-2122	DT	denotes	the
T10903	2123-2127	RBS	denotes	most
T10904	2128-2135	RB	denotes	rapidly
T10905	2136-2144	JJ	denotes	degraded
T10906	2145-2152	NN	denotes	subunit
T10907	2153-2156	CC	denotes	and
T10908	2157-2160	DT	denotes	the
T10909	2161-2165	RBS	denotes	most
T10910	2166-2173	VBN	denotes	studied
T10911	2174-2177	CD	denotes	one
T10912	2177-2178	.	denotes	.
T17838	2223-2231	JJ	denotes	Degraded
T17839	2232-2235	NNP	denotes	CGN
T17840	2236-2245	VBD	denotes	activated
T17841	2246-2249	DT	denotes	the
T17842	2250-2255	JJ	denotes	NF-kB
T17843	2256-2263	NN	denotes	pathway
T17844	2264-2266	IN	denotes	in
T17845	2267-2276	NNS	denotes	monocytes
T17846	2276-2277	.	denotes	.
T17847	2278-2279	DT	denotes	A
T17848	2279-2280	:	denotes	:
T17849	2281-2286	CD	denotes	THP-1
T17850	2287-2292	NNS	denotes	cells
T17851	2293-2297	VBD	denotes	were
T17852	2298-2309	VBN	denotes	transfected
T17853	2310-2314	IN	denotes	with
T17854	2315-2316	DT	denotes	a
T17855	2317-2322	JJ	denotes	NF-κB
T17856	2323-2331	NN	denotes	reporter
T17857	2332-2339	NN	denotes	plasmid
T17858	2340-2347	VBG	denotes	driving
T17859	2348-2358	NN	denotes	expression
T17860	2359-2361	IN	denotes	of
T17861	2362-2372	NN	denotes	luciferase
T17862	2372-2373	.	denotes	.
T17863	2374-2379	NNS	denotes	Cells
T17864	2380-2384	VBD	denotes	were
T17865	2385-2389	RB	denotes	then
T17866	2390-2397	VBN	denotes	treated
T17867	2398-2402	IN	denotes	with
T17868	2403-2410	JJ	denotes	various
T17869	2411-2425	NNS	denotes	concentrations
T17870	2426-2428	IN	denotes	of
T17871	2429-2431	CD	denotes	10
T17872	2432-2435	NN	denotes	kDa
T17873	2436-2437	-LRB-	denotes	(
T17874	2437-2446	NNS	denotes	triangles
T17875	2446-2447	-RRB-	denotes	)
T17876	2447-2448	,	denotes	,
T17877	2449-2451	CC	denotes	or
T17878	2452-2454	CD	denotes	40
T17879	2455-2458	NNP	denotes	kDa
T17880	2459-2463	NNP	denotes	dCGN
T17881	2464-2465	-LRB-	denotes	(
T17882	2465-2472	NNS	denotes	squares
T17883	2472-2473	-RRB-	denotes	)
T17884	2473-2474	.	denotes	.
T17885	2475-2476	NN	denotes	B
T17886	2476-2477	:	denotes	:
T17887	2478-2483	CD	denotes	THP-1
T17888	2484-2489	NNS	denotes	cells
T17889	2490-2497	VBN	denotes	treated
T17890	2498-2502	IN	denotes	with
T17891	2503-2504	CD	denotes	1
T17892	2505-2510	NN	denotes	mg/ml
T17893	2511-2513	IN	denotes	of
T17894	2514-2516	CD	denotes	10
T17895	2517-2520	NNP	denotes	kDa
T17896	2521-2525	NNP	denotes	dCGN
T17897	2526-2527	-LRB-	denotes	(
T17898	2527-2530	NNP	denotes	C10
T17899	2530-2531	-RRB-	denotes	)
T17900	2531-2532	,	denotes	,
T17901	2533-2535	CC	denotes	or
T17902	2536-2540	IN	denotes	with
T17903	2541-2542	CD	denotes	1
T17904	2543-2548	NN	denotes	mg/ml
T17905	2549-2551	IN	denotes	of
T17906	2552-2554	CD	denotes	40
T17907	2555-2558	NNP	denotes	kDa
T17908	2559-2563	NNP	denotes	dCGN
T17909	2564-2565	-LRB-	denotes	(
T17910	2565-2568	NNP	denotes	C40
T17911	2568-2569	-RRB-	denotes	)
T17912	2570-2574	VBD	denotes	were
T17913	2575-2580	VBN	denotes	lysed
T17914	2581-2586	IN	denotes	after
T17915	2587-2594	JJ	denotes	various
T17916	2595-2602	NNS	denotes	periods
T17917	2603-2605	IN	denotes	of
T17918	2606-2610	NN	denotes	time
T17919	2610-2611	.	denotes	.
T17920	2612-2620	NNPS	denotes	Proteins
T17921	2621-2623	IN	denotes	in
T17922	2624-2628	NN	denotes	cell
T17923	2629-2637	NNS	denotes	extracts
T17924	2638-2642	VBD	denotes	were
T17925	2643-2651	VBN	denotes	resolved
T17926	2652-2654	IN	denotes	by
T17927	2655-2663	NNP	denotes	SDS-PAGE
T17928	2664-2667	CC	denotes	and
T17929	2668-2672	RB	denotes	then
T17930	2673-2680	JJ	denotes	Western
T17931	2681-2688	VBN	denotes	blotted
T17932	2689-2692	IN	denotes	for
T17933	2693-2697	NNP	denotes	IκBα
T17934	2698-2700	CC	denotes	or
T17935	2701-2702	VB	denotes	α
T17936	2702-2703	NN	denotes	−
T17937	2703-2710	NN	denotes	tubulin
T17938	2711-2713	IN	denotes	as
T17939	2714-2721	VBG	denotes	loading
T17940	2722-2729	NN	denotes	control
T17941	2729-2730	.	denotes	.
T17942	2731-2732	NNP	denotes	C
T17943	2732-2733	:	denotes	:
T17944	2734-2742	JJ	denotes	Degraded
T17945	2743-2755	NNS	denotes	carrageenans
T17946	2756-2757	-LRB-	denotes	(
T17947	2757-2761	NNP	denotes	dCGN
T17948	2761-2762	-RRB-	denotes	)
T17949	2763-2770	VBD	denotes	induced
T17950	2771-2781	NN	denotes	activation
T17951	2782-2784	IN	denotes	of
T17952	2785-2790	NN	denotes	NF-κB
T17953	2790-2791	.	denotes	.
T17954	2792-2797	CD	denotes	THP-1
T17955	2798-2803	NNS	denotes	cells
T17956	2804-2808	VBD	denotes	were
T17957	2809-2816	VBN	denotes	treated
T17958	2817-2821	IN	denotes	with
T17959	2822-2829	NN	denotes	nothing
T17960	2830-2831	-LRB-	denotes	(
T17961	2831-2838	NN	denotes	control
T17962	2838-2839	-RRB-	denotes	)
T17963	2839-2840	,	denotes	,
T17964	2841-2843	CC	denotes	or
T17965	2844-2848	IN	denotes	with
T17966	2849-2850	CD	denotes	1
T17967	2851-2856	NN	denotes	mg/ml
T17968	2857-2859	IN	denotes	of
T17969	2860-2862	CD	denotes	10
T17970	2863-2866	NNP	denotes	kDa
T17971	2867-2871	NNP	denotes	dCGN
T17972	2872-2873	-LRB-	denotes	(
T17973	2873-2876	NNP	denotes	C10
T17974	2876-2877	-RRB-	denotes	)
T17975	2877-2878	,	denotes	,
T17976	2879-2881	CC	denotes	or
T17977	2882-2886	IN	denotes	with
T17978	2887-2888	CD	denotes	1
T17979	2889-2894	NN	denotes	mg/ml
T17980	2895-2897	IN	denotes	of
T17981	2898-2900	CD	denotes	40
T17982	2901-2904	NNP	denotes	kDa
T17983	2905-2909	NNP	denotes	dCGN
T17984	2910-2911	-LRB-	denotes	(
T17985	2911-2914	NNP	denotes	C40
T17986	2914-2915	-RRB-	denotes	)
T17987	2916-2919	IN	denotes	for
T17988	2920-2922	CD	denotes	30
T17989	2923-2930	NNS	denotes	minutes
T17990	2931-2933	IN	denotes	at
T17991	2934-2936	CD	denotes	37
T17992	2936-2937	CD	denotes	°
T17993	2937-2939	NNP	denotes	C.
T17994	2940-2946	NNP	denotes	Nuclei
T17995	2947-2951	VBD	denotes	were
T17996	2952-2960	VBN	denotes	isolated
T17997	2961-2964	CC	denotes	and
T17998	2965-2970	VBN	denotes	lysed
T17999	2970-2971	.	denotes	.
T18000	2972-2980	NNPS	denotes	Proteins
T18001	2981-2983	IN	denotes	in
T18002	2984-2991	JJ	denotes	nuclear
T18003	2992-3000	NNS	denotes	extracts
T18004	3001-3005	VBD	denotes	were
T18005	3006-3014	VBN	denotes	resolved
T18006	3015-3017	IN	denotes	by
T18007	3018-3026	NNP	denotes	SDS-PAGE
T18008	3027-3030	CC	denotes	and
T18009	3031-3035	RB	denotes	then
T18010	3036-3043	JJ	denotes	Western
T18011	3044-3051	VBN	denotes	blotted
T18012	3052-3055	IN	denotes	for
T18013	3056-3061	NNP	denotes	NF-κB
T18014	3062-3065	CD	denotes	p50
T18015	3066-3073	NN	denotes	subunit
T18016	3074-3075	-LRB-	denotes	(
T18017	3075-3078	CD	denotes	p50
T18018	3078-3079	-RRB-	denotes	)
T18019	3080-3082	CC	denotes	or
T18020	3083-3088	NNP	denotes	NF-κB
T18021	3089-3092	CD	denotes	p65
T18022	3093-3100	NN	denotes	subunit
T18023	3101-3102	-LRB-	denotes	(
T18024	3102-3105	NNS	denotes	p65
T18025	3105-3106	-RRB-	denotes	)
T18026	3106-3107	.	denotes	.
T18027	3108-3113	JJR	denotes	Lower
T18028	3114-3120	NNS	denotes	panels
T18029	3121-3125	VBP	denotes	show
T18030	3126-3133	JJ	denotes	Western
T18031	3134-3139	NNS	denotes	blots
T18032	3140-3142	IN	denotes	of
T18033	3143-3150	JJ	denotes	nuclear
T18034	3151-3154	NNP	denotes	ERK
T18035	3155-3164	VBG	denotes	revealing
T18036	3165-3175	JJ	denotes	equivalent
T18037	3176-3182	NN	denotes	amount
T18038	3183-3185	IN	denotes	of
T18039	3186-3193	NN	denotes	protein
T18040	3194-3196	IN	denotes	in
T18041	3197-3201	DT	denotes	each
T18042	3202-3208	NN	denotes	sample
T18043	3208-3209	.	denotes	.
T18044	3210-3214	NNS	denotes	Data
T18045	3215-3218	VBP	denotes	are
T18046	3219-3233	NN	denotes	representative
T18047	3234-3236	IN	denotes	of
T18048	3237-3242	CD	denotes	three
T18049	3243-3251	JJ	denotes	separate
T18050	3252-3263	NNS	denotes	experiments
T18051	3263-3264	.	denotes	.
T18052	3265-3266	NNP	denotes	D
T18053	3266-3267	:	denotes	:
T18054	3268-3276	JJ	denotes	Degraded
T18055	3277-3288	NN	denotes	carrageenan
T18056	3289-3290	-LRB-	denotes	(
T18057	3290-3294	NNP	denotes	dCGN
T18058	3294-3295	-RRB-	denotes	)
T18059	3296-3303	VBD	denotes	induced
T18060	3304-3314	NN	denotes	activation
T18061	3315-3317	IN	denotes	of
T18062	3318-3323	NN	denotes	NF-κB
T18063	3323-3324	.	denotes	.
T18064	3325-3331	NNP	denotes	Nuclei
T18065	3332-3340	VBD	denotes	isolated
T18066	3341-3345	IN	denotes	from
T18067	3346-3351	CD	denotes	THP-1
T18068	3352-3357	NNS	denotes	cells
T18069	3358-3362	VBD	denotes	were
T18070	3363-3383	JJ	denotes	fluorescence-stained
T18071	3384-3387	IN	denotes	for
T18072	3388-3393	NNP	denotes	NF-κB
T18073	3394-3397	CD	denotes	p50
T18074	3398-3405	NN	denotes	subunit
T18075	3406-3408	CC	denotes	or
T18076	3409-3414	NN	denotes	NF-κB
T18077	3415-3418	NNS	denotes	p65
T18078	3419-3426	VBP	denotes	subunit
T18079	3427-3433	IN	denotes	before
T18080	3434-3435	-LRB-	denotes	(
T18081	3435-3441	VBN	denotes	filled
T18082	3442-3446	NN	denotes	area
T18083	3446-3447	-RRB-	denotes	)
T18084	3448-3450	CC	denotes	or
T18085	3451-3456	IN	denotes	after
T18086	3457-3462	NNS	denotes	cells
T18087	3463-3467	VBD	denotes	were
T18088	3468-3475	VBN	denotes	treated
T18089	3476-3480	IN	denotes	with
T18090	3481-3482	CD	denotes	1
T18091	3483-3488	NN	denotes	mg/ml
T18092	3489-3491	IN	denotes	of
T18093	3492-3494	CD	denotes	10
T18094	3495-3498	NNP	denotes	kDa
T18095	3499-3503	NNP	denotes	dCGN
T18096	3504-3505	-LRB-	denotes	(
T18097	3505-3508	NNP	denotes	C10
T18098	3508-3509	-RRB-	denotes	)
T18099	3509-3510	,	denotes	,
T18100	3511-3513	CC	denotes	or
T18101	3514-3518	IN	denotes	with
T18102	3519-3520	CD	denotes	1
T18103	3521-3526	NN	denotes	mg/ml
T18104	3527-3529	IN	denotes	of
T18105	3530-3532	CD	denotes	40
T18106	3533-3536	NNP	denotes	kDa
T18107	3537-3541	NNP	denotes	dCGN
T18108	3542-3543	-LRB-	denotes	(
T18109	3543-3546	NNP	denotes	C40
T18110	3546-3547	-RRB-	denotes	)
T18111	3548-3551	IN	denotes	for
T18112	3552-3554	CD	denotes	30
T18113	3555-3562	NNS	denotes	minutes
T18114	3563-3565	IN	denotes	at
T18115	3566-3568	CD	denotes	37
T18116	3568-3569	CD	denotes	°
T18117	3569-3571	NNP	denotes	C.
T18118	3572-3578	NNP	denotes	Dashed
T18119	3579-3583	NN	denotes	line
T18120	3584-3595	VBZ	denotes	corresponds
T18121	3596-3598	TO	denotes	to
T18122	3599-3605	VB	denotes	nuclei
T18123	3606-3613	VBN	denotes	stained
T18124	3614-3618	RB	denotes	only
T18125	3619-3623	IN	denotes	with
T18126	3624-3633	JJ	denotes	secondary
T18127	3634-3646	NN	denotes	fluorescence
T18128	3647-3655	NN	denotes	antibody
T18129	3655-3656	.	denotes	.
T18130	3657-3669	NNP	denotes	Fluorescence
T18131	3670-3679	NN	denotes	intensity
T18132	3680-3683	VBD	denotes	was
T18133	3684-3692	VBN	denotes	analyzed
T18134	3693-3695	IN	denotes	by
T18135	3696-3700	NN	denotes	flow
T18136	3701-3710	NN	denotes	cytometry
T18137	3711-3713	IN	denotes	as
T18138	3714-3723	VBN	denotes	described
T18139	3723-3724	.	denotes	.
R9088	T10499	T10501	amod	Degraded,Induce
R9089	T10500	T10501	compound	CGN,Induce
R9090	T10501	T10501	ROOT	Induce,Induce
R9091	T10502	T10503	compound	IκB,Degradation
R9092	T10503	T10501	dobj	Degradation,Induce
R9093	T10504	T10503	cc	and,Degradation
R9094	T10505	T10506	compound	NF-κB,Activation
R9095	T10506	T10517	nsubjpass	Activation,controlled
R9096	T10507	T10508	det	The,expression
R9097	T10508	T10506	appos	expression,Activation
R9098	T10509	T10508	prep	of,expression
R9099	T10510	T10509	pobj	genes,of
R9100	T10511	T10510	acl	encoding,genes
R9101	T10512	T10511	prep	for,encoding
R9102	T10513	T10512	pobj	ICAM-1,for
R9103	T10514	T10513	cc	and,ICAM-1
R9104	T10515	T10513	conj	TNF-α,ICAM-1
R9105	T10516	T10517	auxpass	is,controlled
R9106	T10517	T10501	relcl	controlled,Induce
R9107	T10518	T10517	agent	by,controlled
R9108	T10519	T10521	det	the,factor
R9109	T10520	T10521	amod	nuclear,factor
R9110	T10521	T10522	compound	factor,NF-κB
R9111	T10522	T10518	pobj	NF-κB,by
R9112	T10523	T10517	punct	.,controlled
R9113	T10524	T10525	amod	Site-specific,phosphorylation
R9114	T10525	T10530	nsubj	phosphorylation,leads
R9115	T10526	T10525	prep	of,phosphorylation
R9116	T10527	T10528	det	the,inhibitor
R9117	T10528	T10526	pobj	inhibitor,of
R9118	T10529	T10530	nsubj	IκB,leads
R9119	T10530	T10530	ROOT	leads,leads
R9120	T10531	T10530	prep	to,leads
R9121	T10532	T10533	poss	its,degradation
R9122	T10533	T10531	pobj	degradation,to
R9123	T10534	T10533	prep	by,degradation
R9124	T10535	T10534	pobj	proteasome,by
R9125	T10536	T10531	cc	and,to
R9126	T10537	T10531	conj	to,to
R9127	T10538	T10540	det	a,activation
R9128	T10539	T10540	amod	consequential,activation
R9129	T10540	T10537	pobj	activation,to
R9130	T10541	T10540	prep	of,activation
R9131	T10542	T10544	det	the,pathway
R9132	T10543	T10544	compound	NF-κB,pathway
R9133	T10544	T10541	pobj	pathway,of
R9134	T10545	T10530	punct	.,leads
R9135	T10546	T10556	advcl	Using,confirmed
R9136	T10547	T10549	det	a,plasmid
R9137	T10548	T10549	compound	reporter,plasmid
R9138	T10549	T10546	dobj	plasmid,Using
R9139	T10550	T10549	prep	for,plasmid
R9140	T10551	T10552	amod	NF-κB,activation
R9141	T10552	T10550	pobj	activation,for
R9142	T10553	T10556	punct	",",confirmed
R9143	T10554	T10556	nsubjpass	it,confirmed
R9144	T10555	T10556	auxpass	was,confirmed
R9145	T10556	T10556	ROOT	confirmed,confirmed
R9146	T10557	T10559	mark	that,induced
R9147	T10558	T10559	nsubj	dCGN,induced
R9148	T10559	T10556	ccomp	induced,confirmed
R9149	T10560	T10562	det	a,activation
R9150	T10561	T10562	amod	strong,activation
R9151	T10562	T10559	dobj	activation,induced
R9152	T10563	T10562	prep	of,activation
R9153	T10564	T10563	pobj	NF-κB,of
R9154	T10565	T10559	punct	",",induced
R9155	T10566	T10567	mark	as,reflected
R9156	T10567	T10559	advcl	reflected,induced
R9157	T10568	T10567	agent	by,reflected
R9158	T10569	T10570	det	an,increase
R9159	T10570	T10568	pobj	increase,by
R9160	T10571	T10570	prep	in,increase
R9161	T10572	T10573	compound	luciferase,activity
R9162	T10573	T10571	pobj	activity,in
R9163	T10574	T10576	punct	(,7A
R9164	T10575	T10576	compound	Fig.,7A
R9165	T10576	T10570	appos	7A,increase
R9166	T10577	T10576	punct	),7A
R9167	T10578	T10556	punct	.,confirmed
R9168	T10579	T10580	det	Both,forms
R9169	T10580	T10583	nsubj	forms,used
R9170	T10581	T10580	prep	of,forms
R9171	T10582	T10581	pobj	dCGN,of
R9172	T10583	T10583	ROOT	used,used
R9173	T10584	T10586	amod	induced,activation
R9174	T10585	T10586	compound	NF-κB,activation
R9175	T10586	T10583	dobj	activation,used
R9176	T10587	T10583	prep	in,used
R9177	T10588	T10591	det	a,manner
R9178	T10589	T10590	npadvmod	dose,dependent
R9179	T10590	T10591	amod	dependent,manner
R9180	T10591	T10587	pobj	manner,in
R9181	T10592	T10583	punct	.,used
R9182	T10593	T10597	advmod	However,was
R9183	T10594	T10597	punct	",",was
R9184	T10595	T10596	det	the,effect
R9185	T10596	T10597	nsubj	effect,was
R9186	T10597	T10600	auxpass	was,induced
R9187	T10598	T10599	advmod	more,strongly
R9188	T10599	T10600	advmod	strongly,induced
R9189	T10600	T10600	ROOT	induced,induced
R9190	T10601	T10600	agent	by,induced
R9191	T10602	T10605	det	the,dCGN
R9192	T10603	T10605	nummod	40,dCGN
R9193	T10604	T10605	compound	kDa,dCGN
R9194	T10605	T10601	pobj	dCGN,by
R9195	T10606	T10608	punct	(,7A
R9196	T10607	T10608	compound	Fig.,7A
R9197	T10608	T10605	appos	7A,dCGN
R9198	T10609	T10608	punct	),7A
R9199	T10610	T10600	punct	.,induced
R9200	T10611	T10612	det	These,results
R9201	T10612	T10615	nsubjpass	results,confirmed
R9202	T10613	T10615	auxpass	were,confirmed
R9203	T10614	T10615	advmod	further,confirmed
R9204	T10615	T10615	ROOT	confirmed,confirmed
R9205	T10616	T10615	agent	by,confirmed
R9206	T10617	T10618	advmod	directly,detecting
R9207	T10618	T10616	pcomp	detecting,by
R9208	T10619	T10618	dobj	NF-κB,detecting
R9209	T10620	T10619	prep	in,NF-κB
R9210	T10621	T10623	det	the,nucleus
R9211	T10622	T10623	compound	cell,nucleus
R9212	T10623	T10620	pobj	nucleus,in
R9213	T10624	T10618	prep	by,detecting
R9214	T10625	T10626	amod	Western,blotting
R9215	T10626	T10624	pobj	blotting,by
R9216	T10627	T10626	punct	(,blotting
R9217	T10628	T10629	compound	Fig.,7C
R9218	T10629	T10626	appos	7C,blotting
R9219	T10630	T10629	punct	),7C
R9220	T10631	T10624	cc	and,by
R9221	T10632	T10624	conj	by,by
R9222	T10633	T10632	pobj	FACS,by
R9223	T10634	T10633	punct	(,FACS
R9224	T10635	T10636	compound	Fig.,7D
R9225	T10636	T10633	appos	7D,FACS
R9226	T10637	T10633	punct	),FACS
R9227	T10638	T10615	punct	.,confirmed
R9228	T10639	T10640	det	These,assays
R9229	T10640	T10642	nsubj	assays,allowed
R9230	T10641	T10642	advmod	also,allowed
R9231	T10642	T10642	ROOT	allowed,allowed
R9232	T10643	T10645	nsubj	us,determine
R9233	T10644	T10645	aux	to,determine
R9234	T10645	T10642	ccomp	determine,allowed
R9235	T10646	T10650	nsubjpass	what,activated
R9236	T10647	T10648	compound	NF-κB,subunits
R9237	T10648	T10650	nsubjpass	subunits,activated
R9238	T10649	T10650	auxpass	were,activated
R9239	T10650	T10645	ccomp	activated,determine
R9240	T10651	T10650	agent	by,activated
R9241	T10652	T10651	pobj	dCGN,by
R9242	T10653	T10642	punct	.,allowed
R9243	T10654	T10655	det	Both,forms
R9244	T10655	T10664	nsubj	forms,induced
R9245	T10656	T10655	punct	(,forms
R9246	T10657	T10660	nummod	10,kDa
R9247	T10658	T10657	cc	or,10
R9248	T10659	T10657	conj	40,10
R9249	T10660	T10655	appos	kDa,forms
R9250	T10661	T10655	punct	),forms
R9251	T10662	T10655	prep	of,forms
R9252	T10663	T10662	pobj	dCGN,of
R9253	T10664	T10664	ROOT	induced,induced
R9254	T10665	T10664	dobj	activation,induced
R9255	T10666	T10665	prep	of,activation
R9256	T10667	T10668	det	the,p50
R9257	T10668	T10666	pobj	p50,of
R9258	T10669	T10668	cc	and,p50
R9259	T10670	T10671	nummod	p65,subunits
R9260	T10671	T10665	appos	subunits,activation
R9261	T10672	T10671	prep	of,subunits
R9262	T10673	T10672	pobj	NF-κB,of
R9263	T10674	T10664	punct	.,induced
R9264	T10675	T10677	det	This,factor
R9265	T10676	T10677	amod	nuclear,factor
R9266	T10677	T10678	nsubj	factor,was
R9267	T10678	T10678	ROOT	was,was
R9268	T10679	T10678	acomp	present,was
R9269	T10680	T10679	prep	in,present
R9270	T10681	T10682	amod	low,levels
R9271	T10682	T10680	pobj	levels,in
R9272	T10683	T10682	prep	in,levels
R9273	T10684	T10686	det	the,nucleus
R9274	T10685	T10686	compound	cell,nucleus
R9275	T10686	T10683	pobj	nucleus,in
R9276	T10687	T10678	cc	and,was
R9277	T10688	T10678	conj	increased,was
R9278	T10689	T10688	advmod	considerably,increased
R9279	T10690	T10688	prep	after,increased
R9280	T10691	T10690	pobj	treatment,after
R9281	T10692	T10688	prep	with,increased
R9282	T10693	T10692	pobj	dCGN,with
R9283	T10694	T10678	punct	.,was
R9284	T10695	T10696	amod	Western,blots
R9285	T10696	T10697	nsubj	blots,suggested
R9286	T10697	T10697	ROOT	suggested,suggested
R9287	T10698	T10702	det	the,form
R9288	T10699	T10702	det	the,form
R9289	T10700	T10702	nummod	40,form
R9290	T10701	T10702	compound	kDa,form
R9291	T10702	T10705	nsubj	form,induced
R9292	T10703	T10702	prep	of,form
R9293	T10704	T10703	pobj	dCGN,of
R9294	T10705	T10697	ccomp	induced,suggested
R9295	T10706	T10708	det	a,activation
R9296	T10707	T10708	amod	stronger,activation
R9297	T10708	T10705	dobj	activation,induced
R9298	T10709	T10708	prep	of,activation
R9299	T10710	T10709	pobj	NF-κB,of
R9300	T10711	T10710	punct	(,NF-κB
R9301	T10712	T10713	compound	Fig.,7C
R9302	T10713	T10710	appos	7C,NF-κB
R9303	T10714	T10710	punct	),NF-κB
R9304	T10715	T10697	punct	.,suggested
R9305	T10716	T10719	det	A,assay
R9306	T10717	T10719	amod	more,assay
R9307	T10718	T10719	amod	sentive,assay
R9308	T10719	T10724	nsubj	assay,is
R9309	T10720	T10719	prep	for,assay
R9310	T10721	T10722	amod	nuclear,factor
R9311	T10722	T10723	compound	factor,activation
R9312	T10723	T10720	pobj	activation,for
R9313	T10724	T10724	ROOT	is,is
R9314	T10725	T10726	compound	flow,cytometry
R9315	T10726	T10724	attr	cytometry,is
R9316	T10727	T10726	prep	of,cytometry
R9317	T10728	T10727	pobj	nuclei,of
R9318	T10729	T10726	acl	stained,cytometry
R9319	T10730	T10729	prep	with,stained
R9320	T10731	T10732	amod	specific,antibodies
R9321	T10732	T10730	pobj	antibodies,with
R9322	T10733	T10732	prep	for,antibodies
R9323	T10734	T10736	det	the,factor
R9324	T10735	T10736	amod	nuclear,factor
R9325	T10736	T10733	pobj	factor,for
R9326	T10737	T10736	prep	of,factor
R9327	T10738	T10737	pobj	interest,of
R9328	T10739	T10724	punct	.,is
R9329	T10740	T10754	prep	In,showed
R9330	T10741	T10740	pobj	agreement,In
R9331	T10742	T10741	prep	with,agreement
R9332	T10743	T10745	det	the,data
R9333	T10744	T10745	amod	previous,data
R9334	T10745	T10742	pobj	data,with
R9335	T10746	T10754	punct	",",showed
R9336	T10747	T10748	compound	FACS,analysis
R9337	T10748	T10754	nsubj	analysis,showed
R9338	T10749	T10748	prep	of,analysis
R9339	T10750	T10749	pobj	nuclei,of
R9340	T10751	T10748	prep	from,analysis
R9341	T10752	T10753	nummod	THP-1,cells
R9342	T10753	T10751	pobj	cells,from
R9343	T10754	T10754	ROOT	showed,showed
R9344	T10755	T10757	mark	that,was
R9345	T10756	T10757	expl	there,was
R9346	T10757	T10754	ccomp	was,showed
R9347	T10758	T10760	det	a,level
R9348	T10759	T10760	amod	basal,level
R9349	T10760	T10757	attr	level,was
R9350	T10761	T10760	prep	of,level
R9351	T10762	T10763	amod	nuclear,NF-κB
R9352	T10763	T10761	pobj	NF-κB,of
R9353	T10764	T10763	punct	(,NF-κB
R9354	T10765	T10766	compound	Fig.,7D
R9355	T10766	T10763	appos	7D,NF-κB
R9356	T10767	T10763	punct	),NF-κB
R9357	T10768	T10754	punct	.,showed
R9358	T10769	T10781	advmod	Again,induced
R9359	T10770	T10781	punct	",",induced
R9360	T10771	T10772	det	both,forms
R9361	T10772	T10781	nsubj	forms,induced
R9362	T10773	T10772	punct	(,forms
R9363	T10774	T10777	nummod	10,kDa
R9364	T10775	T10774	cc	or,10
R9365	T10776	T10774	conj	40,10
R9366	T10777	T10772	appos	kDa,forms
R9367	T10778	T10772	punct	),forms
R9368	T10779	T10772	prep	of,forms
R9369	T10780	T10779	pobj	dCGN,of
R9370	T10781	T10781	ROOT	induced,induced
R9371	T10782	T10783	det	an,increase
R9372	T10783	T10781	dobj	increase,induced
R9373	T10784	T10783	prep	of,increase
R9374	T10785	T10786	det	the,p50
R9375	T10786	T10789	nummod	p50,subunits
R9376	T10787	T10786	cc	and,p50
R9377	T10788	T10786	conj	p65,p50
R9378	T10789	T10784	pobj	subunits,of
R9379	T10790	T10789	prep	of,subunits
R9380	T10791	T10790	pobj	NF-κB,of
R9381	T10792	T10783	prep	in,increase
R9382	T10793	T10794	det	the,nucleus
R9383	T10794	T10792	pobj	nucleus,in
R9384	T10795	T10794	prep	of,nucleus
R9385	T10796	T10797	det	these,cells
R9386	T10797	T10795	pobj	cells,of
R9387	T10798	T10781	punct	.,induced
R9388	T10799	T10803	det	The,CGN
R9389	T10800	T10801	nummod	40,kDa
R9390	T10801	T10803	nmod	kDa,CGN
R9391	T10802	T10803	amod	degraded,CGN
R9392	T10803	T10804	nsubj	CGN,gave
R9393	T10804	T10804	ROOT	gave,gave
R9394	T10805	T10807	det	a,increase
R9395	T10806	T10807	amod	stronger,increase
R9396	T10807	T10804	dobj	increase,gave
R9397	T10808	T10807	prep	of,increase
R9398	T10809	T10808	pobj	NF-κB,of
R9399	T10810	T10812	punct	(,7D
R9400	T10811	T10812	compound	Fig.,7D
R9401	T10812	T10809	appos	7D,NF-κB
R9402	T10813	T10812	punct	),7D
R9403	T10814	T10804	punct	.,gave
R9404	T10815	T10816	det	These,data
R9405	T10816	T10818	nsubj	data,suggest
R9406	T10817	T10818	advmod	strongly,suggest
R9407	T10818	T10818	ROOT	suggest,suggest
R9408	T10819	T10823	mark	that,is
R9409	T10820	T10823	advmod	the,is
R9410	T10821	T10823	nsubj	heterodimer,is
R9411	T10822	T10821	nummod	p50/p65,heterodimer
R9412	T10823	T10818	ccomp	is,suggest
R9413	T10824	T10826	det	the,isoform
R9414	T10825	T10826	amod	NF-κB,isoform
R9415	T10826	T10823	attr	isoform,is
R9416	T10827	T10826	acl	activated,isoform
R9417	T10828	T10827	agent	by,activated
R9418	T10829	T10830	amod	degraded,CGN
R9419	T10830	T10828	pobj	CGN,by
R9420	T10831	T10827	prep	in,activated
R9421	T10832	T10831	pobj	monocytes,in
R9422	T10833	T10818	punct	.,suggest
R9423	T10834	T10844	prep	In,observed
R9424	T10835	T10834	pobj	addition,In
R9425	T10836	T10844	punct	",",observed
R9426	T10837	T10844	nsubjpass	degradation,observed
R9427	T10838	T10837	prep	of,degradation
R9428	T10839	T10840	det	the,inhibitor
R9429	T10840	T10838	pobj	inhibitor,of
R9430	T10841	T10844	nsubjpass	IκBα,observed
R9431	T10842	T10844	auxpass	was,observed
R9432	T10843	T10844	advmod	also,observed
R9433	T10844	T10844	ROOT	observed,observed
R9434	T10845	T10844	prep	in,observed
R9435	T10846	T10845	pobj	cells,in
R9436	T10847	T10846	acl	treated,cells
R9437	T10848	T10847	prep	with,treated
R9438	T10849	T10848	pobj	dCGN,with
R9439	T10850	T10852	punct	(,7B
R9440	T10851	T10852	compound	Fig.,7B
R9441	T10852	T10849	appos	7B,dCGN
R9442	T10853	T10852	punct	),7B
R9443	T10854	T10844	punct	.,observed
R9444	T10855	T10858	det	No,degradation
R9445	T10856	T10858	amod	significant,degradation
R9446	T10857	T10858	compound	IκBα,degradation
R9447	T10858	T10860	nsubjpass	degradation,detected
R9448	T10859	T10860	auxpass	was,detected
R9449	T10860	T10860	ROOT	detected,detected
R9450	T10861	T10860	prep	within,detected
R9451	T10862	T10863	nummod	two,hours
R9452	T10863	T10861	pobj	hours,within
R9453	T10864	T10863	prep	of,hours
R9454	T10865	T10866	compound	dCGN,treatment
R9455	T10866	T10864	pobj	treatment,of
R9456	T10867	T10860	punct	",",detected
R9457	T10868	T10860	cc	but,detected
R9458	T10869	T10870	nsubj	IκBα,was
R9459	T10870	T10872	auxpass	was,degraded
R9460	T10871	T10872	advmod	markedly,degraded
R9461	T10872	T10860	conj	degraded,detected
R9462	T10873	T10872	prep	by,degraded
R9463	T10874	T10875	nummod	four,hours
R9464	T10875	T10873	pobj	hours,by
R9465	T10876	T10875	prep	of,hours
R9482	T10893	T10896	det	the,sequence
R9483	T10894	T10895	amod	nuclear,localisation
R9484	T10895	T10896	compound	localisation,sequence
R9485	T10896	T10892	dobj	sequence,masks
R9486	T10897	T10896	prep	of,sequence
R9487	T10898	T10897	pobj	p65,of
R9488	T10899	T10901	punct	",",is
R9489	T10900	T10901	nsubj	it,is
R9490	T10901	T10901	ROOT	is,is
R9491	T10902	T10906	det	the,subunit
R9492	T10903	T10905	advmod	most,degraded
R9493	T10904	T10905	advmod	rapidly,degraded
R9494	T10905	T10906	amod	degraded,subunit
R9495	T10906	T10901	attr	subunit,is
R9496	T10907	T10906	cc	and,subunit
R9497	T10908	T10911	det	the,one
R9498	T10909	T10910	advmod	most,studied
R9499	T10910	T10911	amod	studied,one
R9500	T10911	T10906	conj	one,subunit
R9501	T10912	T10901	punct	.,is
R15238	T17838	T17839	amod	Degraded,CGN
R15239	T17839	T17840	nsubj	CGN,activated
R15240	T17840	T17840	ROOT	activated,activated
R15241	T17841	T17843	det	the,pathway
R15242	T17842	T17843	amod	NF-kB,pathway
R15243	T17843	T17840	dobj	pathway,activated
R15244	T17844	T17843	prep	in,pathway
R15245	T17845	T17844	pobj	monocytes,in
R15246	T17846	T17840	punct	.,activated
R15247	T17847	T17847	ROOT	A,A
R15248	T17848	T17847	punct	:,A
R15249	T17849	T17850	nummod	THP-1,cells
R15250	T17850	T17852	nsubjpass	cells,transfected
R15251	T17851	T17852	auxpass	were,transfected
R15252	T17852	T17852	ROOT	transfected,transfected
R15253	T17853	T17852	prep	with,transfected
R15254	T17854	T17856	det	a,reporter
R15255	T17855	T17856	amod	NF-κB,reporter
R15256	T17856	T17858	nsubj	reporter,driving
R15257	T17857	T17858	npadvmod	plasmid,driving
R15258	T17858	T17859	amod	driving,expression
R15259	T17859	T17853	pobj	expression,with
R15260	T17860	T17859	prep	of,expression
R15261	T17861	T17860	pobj	luciferase,of
R15262	T17862	T17852	punct	.,transfected
R15263	T17863	T17866	nsubjpass	Cells,treated
R15264	T17864	T17866	auxpass	were,treated
R15265	T17865	T17866	advmod	then,treated
R15266	T17866	T17866	ROOT	treated,treated
R15267	T17867	T17866	prep	with,treated
R15268	T17868	T17869	amod	various,concentrations
R15269	T17869	T17867	pobj	concentrations,with
R15270	T17870	T17869	prep	of,concentrations
R15271	T17871	T17872	nummod	10,kDa
R15272	T17872	T17870	pobj	kDa,of
R15273	T17873	T17874	punct	(,triangles
R15274	T17874	T17872	appos	triangles,kDa
R15275	T17875	T17872	punct	),kDa
R15276	T17876	T17869	punct	",",concentrations
R15277	T17877	T17869	cc	or,concentrations
R15278	T17878	T17880	nummod	40,dCGN
R15279	T17879	T17880	compound	kDa,dCGN
R15280	T17880	T17869	conj	dCGN,concentrations
R15281	T17881	T17882	punct	(,squares
R15282	T17882	T17880	parataxis	squares,dCGN
R15283	T17883	T17882	punct	),squares
R15284	T17884	T17866	punct	.,treated
R15285	T17885	T17913	nsubjpass	B,lysed
R15286	T17886	T17885	punct	:,B
R15287	T17887	T17888	nummod	THP-1,cells
R15288	T17888	T17885	appos	cells,B
R15289	T17889	T17888	acl	treated,cells
R15290	T17890	T17889	prep	with,treated
R15291	T17891	T17892	nummod	1,mg/ml
R15292	T17892	T17890	pobj	mg/ml,with
R15293	T17893	T17892	prep	of,mg/ml
R15294	T17894	T17896	nummod	10,dCGN
R15295	T17895	T17896	compound	kDa,dCGN
R15296	T17896	T17893	pobj	dCGN,of
R15297	T17897	T17898	punct	(,C10
R15298	T17898	T17896	appos	C10,dCGN
R15299	T17899	T17898	punct	),C10
R15300	T17900	T17896	punct	",",dCGN
R15301	T17901	T17890	cc	or,with
R15302	T17902	T17890	conj	with,with
R15303	T17903	T17904	nummod	1,mg/ml
R15304	T17904	T17902	pobj	mg/ml,with
R15305	T17905	T17904	prep	of,mg/ml
R15306	T17906	T17908	nummod	40,dCGN
R15307	T17907	T17908	compound	kDa,dCGN
R15308	T17908	T17905	pobj	dCGN,of
R15309	T17909	T17908	punct	(,dCGN
R15310	T17910	T17908	appos	C40,dCGN
R15311	T17911	T17908	punct	),dCGN
R15312	T17912	T17913	auxpass	were,lysed
R15313	T17913	T17913	ROOT	lysed,lysed
R15314	T17914	T17913	prep	after,lysed
R15315	T17915	T17916	amod	various,periods
R15316	T17916	T17914	pobj	periods,after
R15317	T17917	T17916	prep	of,periods
R15318	T17918	T17917	pobj	time,of
R15319	T17919	T17913	punct	.,lysed
R15320	T17920	T17925	nsubjpass	Proteins,resolved
R15321	T17921	T17920	prep	in,Proteins
R15322	T17922	T17923	compound	cell,extracts
R15323	T17923	T17921	pobj	extracts,in
R15324	T17924	T17925	auxpass	were,resolved
R15325	T17925	T17925	ROOT	resolved,resolved
R15326	T17926	T17925	agent	by,resolved
R15327	T17927	T17926	pobj	SDS-PAGE,by
R15328	T17928	T17925	cc	and,resolved
R15329	T17929	T17931	advmod	then,blotted
R15330	T17930	T17931	amod	Western,blotted
R15331	T17931	T17925	conj	blotted,resolved
R15332	T17932	T17931	prep	for,blotted
R15333	T17933	T17932	pobj	IκBα,for
R15334	T17934	T17931	cc	or,blotted
R15335	T17935	T17931	conj	α,blotted
R15336	T17936	T17937	compound	−,tubulin
R15337	T17937	T17935	dobj	tubulin,α
R15338	T17938	T17937	prep	as,tubulin
R15339	T17939	T17938	pcomp	loading,as
R15340	T17940	T17939	dobj	control,loading
R15341	T17941	T17925	punct	.,resolved
R15342	T17942	T17949	nsubj	C,induced
R15343	T17943	T17942	punct	:,C
R15344	T17944	T17945	amod	Degraded,carrageenans
R15345	T17945	T17942	appos	carrageenans,C
R15346	T17946	T17945	punct	(,carrageenans
R15347	T17947	T17945	appos	dCGN,carrageenans
R15348	T17948	T17945	punct	),carrageenans
R15349	T17949	T17949	ROOT	induced,induced
R15350	T17950	T17949	dobj	activation,induced
R15351	T17951	T17950	prep	of,activation
R15352	T17952	T17951	pobj	NF-κB,of
R15353	T17953	T17949	punct	.,induced
R15354	T17954	T17955	nummod	THP-1,cells
R15355	T17955	T17957	nsubjpass	cells,treated
R15356	T17956	T17957	auxpass	were,treated
R15357	T17957	T17957	ROOT	treated,treated
R15358	T17958	T17957	prep	with,treated
R15359	T17959	T17958	pobj	nothing,with
R15360	T17960	T17959	punct	(,nothing
R15361	T17961	T17959	appos	control,nothing
R15362	T17962	T17959	punct	),nothing
R15363	T17963	T17958	punct	",",with
R15364	T17964	T17958	cc	or,with
R15365	T17965	T17958	conj	with,with
R15366	T17966	T17967	nummod	1,mg/ml
R15367	T17967	T17965	pobj	mg/ml,with
R15368	T17968	T17967	prep	of,mg/ml
R15369	T17969	T17971	nummod	10,dCGN
R15370	T17970	T17971	compound	kDa,dCGN
R15371	T17971	T17968	pobj	dCGN,of
R15372	T17972	T17973	punct	(,C10
R15373	T17973	T17971	appos	C10,dCGN
R15374	T17974	T17971	punct	),dCGN
R15375	T17975	T17967	punct	",",mg/ml
R15376	T17976	T17965	cc	or,with
R15377	T17977	T17965	conj	with,with
R15378	T17978	T17979	nummod	1,mg/ml
R15379	T17979	T17977	pobj	mg/ml,with
R15380	T17980	T17979	prep	of,mg/ml
R15381	T17981	T17983	nummod	40,dCGN
R15382	T17982	T17983	compound	kDa,dCGN
R15383	T17983	T17980	pobj	dCGN,of
R15384	T17984	T17983	punct	(,dCGN
R15385	T17985	T17983	appos	C40,dCGN
R15386	T17986	T17983	punct	),dCGN
R15387	T17987	T17979	prep	for,mg/ml
R15388	T17988	T17989	nummod	30,minutes
R15389	T17989	T17987	pobj	minutes,for
R15390	T17990	T17989	prep	at,minutes
R15391	T17991	T17992	nummod	37,°
R15392	T17992	T17994	nummod	°,Nuclei
R15393	T17993	T17994	compound	C.,Nuclei
R15394	T17994	T17990	pobj	Nuclei,at
R15395	T17995	T17957	auxpass	were,treated
R15396	T17996	T17995	acomp	isolated,were
R15397	T17997	T17996	cc	and,isolated
R15398	T17998	T17996	conj	lysed,isolated
R15399	T17999	T17957	punct	.,treated
R15400	T18000	T18005	nsubjpass	Proteins,resolved
R15401	T18001	T18000	prep	in,Proteins
R15402	T18002	T18003	amod	nuclear,extracts
R15403	T18003	T18001	pobj	extracts,in
R15404	T18004	T18005	auxpass	were,resolved
R15405	T18005	T18005	ROOT	resolved,resolved
R15406	T18006	T18005	agent	by,resolved
R15407	T18007	T18006	pobj	SDS-PAGE,by
R15408	T18008	T18005	cc	and,resolved
R15409	T18009	T18011	advmod	then,blotted
R15410	T18010	T18011	amod	Western,blotted
R15411	T18011	T18005	conj	blotted,resolved
R15412	T18012	T18011	prep	for,blotted
R15413	T18013	T18015	nmod	NF-κB,subunit
R15414	T18014	T18015	nummod	p50,subunit
R15415	T18015	T18012	pobj	subunit,for
R15416	T18016	T18015	punct	(,subunit
R15417	T18017	T18015	appos	p50,subunit
R15418	T18018	T18017	punct	),p50
R15419	T18019	T18015	cc	or,subunit
R15420	T18020	T18022	nmod	NF-κB,subunit
R15421	T18021	T18020	nummod	p65,NF-κB
R15422	T18022	T18015	conj	subunit,subunit
R15423	T18023	T18024	punct	(,p65
R15424	T18024	T18022	appos	p65,subunit
R15425	T18025	T18011	punct	),blotted
R15426	T18026	T18005	punct	.,resolved
R15427	T18027	T18028	amod	Lower,panels
R15428	T18028	T18029	nsubj	panels,show
R15429	T18029	T18029	ROOT	show,show
R15430	T18030	T18031	amod	Western,blots
R15431	T18031	T18029	dobj	blots,show
R15432	T18032	T18031	prep	of,blots
R15433	T18033	T18034	amod	nuclear,ERK
R15434	T18034	T18035	nsubj	ERK,revealing
R15435	T18035	T18032	pcomp	revealing,of
R15436	T18036	T18037	amod	equivalent,amount
R15437	T18037	T18035	dobj	amount,revealing
R15438	T18038	T18037	prep	of,amount
R15439	T18039	T18038	pobj	protein,of
R15440	T18040	T18035	prep	in,revealing
R15441	T18041	T18042	det	each,sample
R15442	T18042	T18040	pobj	sample,in
R15443	T18043	T18029	punct	.,show
R15444	T18044	T18045	nsubj	Data,are
R15445	T18045	T18045	ROOT	are,are
R15446	T18046	T18045	attr	representative,are
R15447	T18047	T18046	prep	of,representative
R15448	T18048	T18050	nummod	three,experiments
R15449	T18049	T18050	amod	separate,experiments
R15450	T18050	T18047	pobj	experiments,of
R15451	T18051	T18045	punct	.,are
R15452	T18052	T18059	nsubj	D,induced
R15453	T18053	T18052	punct	:,D
R15454	T18054	T18055	amod	Degraded,carrageenan
R15455	T18055	T18052	appos	carrageenan,D
R15456	T18056	T18057	punct	(,dCGN
R15457	T18057	T18055	appos	dCGN,carrageenan
R15458	T18058	T18055	punct	),carrageenan
R15459	T18059	T18059	ROOT	induced,induced
R15460	T18060	T18059	dobj	activation,induced
R15461	T18061	T18060	prep	of,activation
R15462	T18062	T18061	pobj	NF-κB,of
R15463	T18063	T18059	punct	.,induced
R15466	T18066	T18065	prep	from,isolated
R15467	T18067	T18068	nummod	THP-1,cells
R15468	T18068	T18066	pobj	cells,from
R15469	T18069	T18065	conj	were,isolated
R15470	T18070	T18069	acomp	fluorescence-stained,were
R15471	T18071	T18070	prep	for,fluorescence-stained
R15472	T18072	T18074	nmod	NF-κB,subunit
R15473	T18073	T18074	nummod	p50,subunit
R15474	T18074	T18071	pobj	subunit,for
R15475	T18075	T18074	cc	or,subunit
R15476	T18076	T18077	compound	NF-κB,p65
R15477	T18077	T18078	compound	p65,subunit
R15478	T18078	T18074	conj	subunit,subunit
R15479	T18079	T18078	prep	before,subunit
R15480	T18080	T18081	punct	(,filled
R15481	T18081	T18082	amod	filled,area
R15482	T18082	T18079	pobj	area,before
R15483	T18083	T18078	punct	),subunit
R15484	T18084	T18070	cc	or,fluorescence-stained
R15485	T18085	T18088	mark	after,treated
R15486	T18086	T18088	nsubjpass	cells,treated
R15487	T18087	T18088	auxpass	were,treated
R15488	T18088	T18069	advcl	treated,were
R15489	T18089	T18088	prep	with,treated
R15490	T18090	T18091	nummod	1,mg/ml
R15491	T18091	T18089	pobj	mg/ml,with
R15492	T18092	T18091	prep	of,mg/ml
R15493	T18093	T18095	nummod	10,dCGN
R15494	T18094	T18095	compound	kDa,dCGN
R15495	T18095	T18092	pobj	dCGN,of
R15496	T18096	T18097	punct	(,C10
R15497	T18097	T18095	appos	C10,dCGN
R15498	T18098	T18097	punct	),C10
R15499	T18099	T18095	punct	",",dCGN
R15500	T18100	T18089	cc	or,with
R15501	T18101	T18089	conj	with,with
R15502	T18102	T18103	nummod	1,mg/ml
R15503	T18103	T18101	pobj	mg/ml,with
R15504	T18104	T18103	prep	of,mg/ml
R15505	T18105	T18107	nummod	40,dCGN
R15506	T18106	T18107	compound	kDa,dCGN
R15507	T18107	T18104	pobj	dCGN,of
R15508	T18108	T18107	punct	(,dCGN
R15509	T18109	T18107	appos	C40,dCGN
R15510	T18110	T18107	punct	),dCGN
R15511	T18111	T18103	prep	for,mg/ml
R15512	T18112	T18113	nummod	30,minutes
R15513	T18113	T18111	pobj	minutes,for
R15514	T18114	T18113	prep	at,minutes
R15515	T18115	T18116	nummod	37,°
R15516	T18116	T18120	nummod	°,corresponds
R15517	T18117	T18118	compound	C.,Dashed
R15518	T18118	T18119	compound	Dashed,line
R15519	T18119	T18120	nsubj	line,corresponds
R15520	T18120	T18120	ROOT	corresponds,corresponds
R15521	T18121	T18123	aux	to,stained
R15522	T18122	T18123	nsubj	nuclei,stained
R15523	T18123	T18120	xcomp	stained,corresponds
R15524	T18124	T18125	advmod	only,with
R15525	T18125	T18123	prep	with,stained
R15526	T18126	T18128	amod	secondary,antibody
R15527	T18127	T18128	compound	fluorescence,antibody
R15528	T18128	T18125	pobj	antibody,with
R15529	T18129	T18065	punct	.,isolated
R15530	T18130	T18131	compound	Fluorescence,intensity
R15531	T18131	T18133	nsubjpass	intensity,analyzed
R15532	T18132	T18133	auxpass	was,analyzed
R15533	T18133	T18133	ROOT	analyzed,analyzed
R15534	T18134	T18133	agent	by,analyzed
R15535	T18135	T18136	compound	flow,cytometry
R15536	T18136	T18134	pobj	cytometry,by
R15537	T18137	T18138	mark	as,described
R15538	T18138	T18133	advcl	described,analyzed
R15539	T18139	T18133	punct	.,analyzed
R15464	T18064	T18065	nsubj	Nuclei,isolated
R15465	T18065	T18065	ROOT	isolated,isolated
R9466	T10877	T10878	compound	dCGN,treatment
R9467	T10878	T10876	pobj	treatment,of
R9468	T10879	T10881	punct	(,7B
R9469	T10880	T10881	compound	Fig.,7B
R9470	T10881	T10878	appos	7B,treatment
R9471	T10882	T10881	punct	),7B
R9472	T10883	T10860	punct	.,detected
R9473	T10884	T10885	nsubj	We,focused
R9474	T10885	T10901	ccomp	focused,is
R9475	T10886	T10885	prep	on,focused
R9476	T10887	T10888	compound	IκBα,subunit
R9477	T10888	T10886	pobj	subunit,on
R9478	T10889	T10885	punct	",",focused
R9479	T10890	T10892	mark	since,masks
R9480	T10891	T10892	nsubj	it,masks
R9481	T10892	T10901	advcl	masks,is

sentences

Id	Subject	Object	Predicate	Lexical cue
T10061	0-56	Sentence	denotes	Degraded CGN Induce IκB Degradation and NF-κB Activation
T10062	57-153	Sentence	denotes	The expression of genes encoding for ICAM-1 and TNF-α is controlled by the nuclear factor NF-κB.
T10063	154-299	Sentence	denotes	Site-specific phosphorylation of the inhibitor IκB leads to its degradation by proteasome and to a consequential activation of the NF-κB pathway.
T10064	300-473	Sentence	denotes	Using a reporter plasmid for NF-κB activation, it was confirmed that dCGN induced a strong activation of NF-κB, as reflected by an increase in luciferase activity (Fig. 7A).
T10065	474-550	Sentence	denotes	Both forms of dCGN used induced NF-κB activation in a dose dependent manner.
T10066	551-626	Sentence	denotes	However, the effect was more strongly induced by the 40 kDa dCGN (Fig. 7A).
T10067	627-764	Sentence	denotes	These results were further confirmed by directly detecting NF-κB in the cell nucleus by Western blotting (Fig. 7C) and by FACS (Fig. 7D).
T10068	765-850	Sentence	denotes	These assays also allowed us to determine what NF-κB subunits were activated by dCGN.
T10069	851-941	Sentence	denotes	Both forms (10 or 40 kDa) of dCGN induced activation of the p50 and p65 subunits of NF-κB.
T10070	942-1061	Sentence	denotes	This nuclear factor was present in low levels in the cell nucleus and increased considerably after treatment with dCGN.
T10071	1062-1163	Sentence	denotes	Western blots suggested the the 40 kDa form of dCGN induced a stronger activation of NF-κB (Fig. 7C).
T10072	1164-1311	Sentence	denotes	A more sentive assay for nuclear factor activation is flow cytometry of nuclei stained with specific antibodies for the nuclear factor of interest.
T10073	1312-1453	Sentence	denotes	In agreement with the previous data, FACS analysis of nuclei from THP-1 cells showed that there was a basal level of nuclear NF-κB (Fig. 7D).
T10074	1454-1582	Sentence	denotes	Again, both forms (10 or 40 kDa) of dCGN induced an increase of the p50 and p65 subunits of NF-κB in the nucleus of these cells.
T10075	1583-1651	Sentence	denotes	The 40 kDa degraded CGN gave a stronger increase of NF-κB (Fig. 7D).
T10076	1652-1769	Sentence	denotes	These data strongly suggest that the heterodimer p50/p65 is the NF-κB isoform activated by degraded CGN in monocytes.
T10077	1770-1872	Sentence	denotes	In addition, degradation of the inhibitor IκBα was also observed in cells treated with dCGN (Fig. 7B).
T10078	1873-2027	Sentence	denotes	No significant IκBα degradation was detected within two hours of dCGN treatment, but IκBα was markedly degraded by four hours of dCGN treatment (Fig. 7B).
T10079	2028-2178	Sentence	denotes	We focused on IκBα subunit, since it masks the nuclear localisation sequence of p65, it is the most rapidly degraded subunit and the most studied one.
T17527	2223-2277	Sentence	denotes	Degraded CGN activated the NF-kB pathway in monocytes.
T17528	2278-2373	Sentence	denotes	A: THP-1 cells were transfected with a NF-κB reporter plasmid driving expression of luciferase.
T17529	2374-2474	Sentence	denotes	Cells were then treated with various concentrations of 10 kDa (triangles), or 40 kDa dCGN (squares).
T17530	2475-2611	Sentence	denotes	B: THP-1 cells treated with 1 mg/ml of 10 kDa dCGN (C10), or with 1 mg/ml of 40 kDa dCGN (C40) were lysed after various periods of time.
T17531	2612-2730	Sentence	denotes	Proteins in cell extracts were resolved by SDS-PAGE and then Western blotted for IκBα or α−tubulin as loading control.
T17532	2731-2733	Sentence	denotes	C:
T17533	2734-2791	Sentence	denotes	Degraded carrageenans (dCGN) induced activation of NF-κB.
T17534	2792-2971	Sentence	denotes	THP-1 cells were treated with nothing (control), or with 1 mg/ml of 10 kDa dCGN (C10), or with 1 mg/ml of 40 kDa dCGN (C40) for 30 minutes at 37°C. Nuclei were isolated and lysed.
T17535	2972-3107	Sentence	denotes	Proteins in nuclear extracts were resolved by SDS-PAGE and then Western blotted for NF-κB p50 subunit (p50) or NF-κB p65 subunit (p65).
T17536	3108-3209	Sentence	denotes	Lower panels show Western blots of nuclear ERK revealing equivalent amount of protein in each sample.
T17537	3210-3264	Sentence	denotes	Data are representative of three separate experiments.
T17538	3265-3267	Sentence	denotes	D:
T17539	3268-3324	Sentence	denotes	Degraded carrageenan (dCGN) induced activation of NF-κB.
T17540	3325-3656	Sentence	denotes	Nuclei isolated from THP-1 cells were fluorescence-stained for NF-κB p50 subunit or NF-κB p65 subunit before (filled area) or after cells were treated with 1 mg/ml of 10 kDa dCGN (C10), or with 1 mg/ml of 40 kDa dCGN (C40) for 30 minutes at 37°C. Dashed line corresponds to nuclei stained only with secondary fluorescence antibody.
T17541	3657-3724	Sentence	denotes	Fluorescence intensity was analyzed by flow cytometry as described.
T226	0-56	Sentence	denotes	Degraded CGN Induce IκB Degradation and NF-κB Activation
T227	57-153	Sentence	denotes	The expression of genes encoding for ICAM-1 and TNF-α is controlled by the nuclear factor NF-κB.
T228	154-299	Sentence	denotes	Site-specific phosphorylation of the inhibitor IκB leads to its degradation by proteasome and to a consequential activation of the NF-κB pathway.
T229	300-473	Sentence	denotes	Using a reporter plasmid for NF-κB activation, it was confirmed that dCGN induced a strong activation of NF-κB, as reflected by an increase in luciferase activity (Fig. 7A).
T230	474-550	Sentence	denotes	Both forms of dCGN used induced NF-κB activation in a dose dependent manner.
T231	551-626	Sentence	denotes	However, the effect was more strongly induced by the 40 kDa dCGN (Fig. 7A).
T232	627-764	Sentence	denotes	These results were further confirmed by directly detecting NF-κB in the cell nucleus by Western blotting (Fig. 7C) and by FACS (Fig. 7D).
T233	765-850	Sentence	denotes	These assays also allowed us to determine what NF-κB subunits were activated by dCGN.
T234	851-941	Sentence	denotes	Both forms (10 or 40 kDa) of dCGN induced activation of the p50 and p65 subunits of NF-κB.
T235	942-1061	Sentence	denotes	This nuclear factor was present in low levels in the cell nucleus and increased considerably after treatment with dCGN.
T236	1062-1163	Sentence	denotes	Western blots suggested the the 40 kDa form of dCGN induced a stronger activation of NF-κB (Fig. 7C).
T237	1164-1311	Sentence	denotes	A more sentive assay for nuclear factor activation is flow cytometry of nuclei stained with specific antibodies for the nuclear factor of interest.
T238	1312-1453	Sentence	denotes	In agreement with the previous data, FACS analysis of nuclei from THP-1 cells showed that there was a basal level of nuclear NF-κB (Fig. 7D).
T239	1454-1582	Sentence	denotes	Again, both forms (10 or 40 kDa) of dCGN induced an increase of the p50 and p65 subunits of NF-κB in the nucleus of these cells.
T240	1583-1651	Sentence	denotes	The 40 kDa degraded CGN gave a stronger increase of NF-κB (Fig. 7D).
T241	1652-1769	Sentence	denotes	These data strongly suggest that the heterodimer p50/p65 is the NF-κB isoform activated by degraded CGN in monocytes.
T242	1770-1872	Sentence	denotes	In addition, degradation of the inhibitor IκBα was also observed in cells treated with dCGN (Fig. 7B).
T243	1873-2027	Sentence	denotes	No significant IκBα degradation was detected within two hours of dCGN treatment, but IκBα was markedly degraded by four hours of dCGN treatment (Fig. 7B).
T244	2028-2178	Sentence	denotes	We focused on IκBα subunit, since it masks the nuclear localisation sequence of p65, it is the most rapidly degraded subunit and the most studied one.
T245	2179-2277	Sentence	denotes	10.1371/journal.pone.0008666.g007 Figure 7 Degraded CGN activated the NF-kB pathway in monocytes.
T246	2278-2373	Sentence	denotes	A: THP-1 cells were transfected with a NF-κB reporter plasmid driving expression of luciferase.
T247	2374-2474	Sentence	denotes	Cells were then treated with various concentrations of 10 kDa (triangles), or 40 kDa dCGN (squares).
T248	2475-2611	Sentence	denotes	B: THP-1 cells treated with 1 mg/ml of 10 kDa dCGN (C10), or with 1 mg/ml of 40 kDa dCGN (C40) were lysed after various periods of time.
T249	2612-2730	Sentence	denotes	Proteins in cell extracts were resolved by SDS-PAGE and then Western blotted for IκBα or α−tubulin as loading control.
T250	2731-2733	Sentence	denotes	C:
T251	2734-2791	Sentence	denotes	Degraded carrageenans (dCGN) induced activation of NF-κB.
T252	2792-2939	Sentence	denotes	THP-1 cells were treated with nothing (control), or with 1 mg/ml of 10 kDa dCGN (C10), or with 1 mg/ml of 40 kDa dCGN (C40) for 30 minutes at 37°C.
T253	2940-2971	Sentence	denotes	Nuclei were isolated and lysed.
T254	2972-3107	Sentence	denotes	Proteins in nuclear extracts were resolved by SDS-PAGE and then Western blotted for NF-κB p50 subunit (p50) or NF-κB p65 subunit (p65).
T255	3108-3209	Sentence	denotes	Lower panels show Western blots of nuclear ERK revealing equivalent amount of protein in each sample.
T256	3210-3264	Sentence	denotes	Data are representative of three separate experiments.
T257	3265-3267	Sentence	denotes	D:
T258	3268-3324	Sentence	denotes	Degraded carrageenan (dCGN) induced activation of NF-κB.
T259	3325-3571	Sentence	denotes	Nuclei isolated from THP-1 cells were fluorescence-stained for NF-κB p50 subunit or NF-κB p65 subunit before (filled area) or after cells were treated with 1 mg/ml of 10 kDa dCGN (C10), or with 1 mg/ml of 40 kDa dCGN (C40) for 30 minutes at 37°C.
T260	3572-3656	Sentence	denotes	Dashed line corresponds to nuclei stained only with secondary fluorescence antibody.
T261	3657-3724	Sentence	denotes	Fluorescence intensity was analyzed by flow cytometry as described.

events-check-again

Id	Subject	Object	Predicate	Lexical cue	Negation	Speculation
T11037	61-71	Gene_expression	denotes	expression
T11038	61-71	Gene_expression	denotes	expression
T11039	94-100	Protein	denotes	ICAM-1
T11040	105-110	Protein	denotes	TNF-α
T11041	114-124	Regulation	denotes	controlled
T11042	114-124	Regulation	denotes	controlled
T11043	431-439	Positive_regulation	denotes	increase
T11044	443-453	Protein	denotes	luciferase
T11045	812-826	Protein	denotes	NF-κB subunits
T11046	885-892	Positive_regulation	denotes	induced
T11047	885-892	Positive_regulation	denotes	induced
T11048	893-903	Positive_regulation	denotes	activation
T11049	893-903	Positive_regulation	denotes	activation
T11050	911-914	Protein	denotes	p50
T11051	919-922	Protein	denotes	p65
T11052	1495-1502	Positive_regulation	denotes	induced
T11053	1495-1502	Positive_regulation	denotes	induced
T11054	1506-1514	Positive_regulation	denotes	increase
T11055	1506-1514	Positive_regulation	denotes	increase
T11056	1522-1525	Protein	denotes	p50
T11057	1530-1533	Protein	denotes	p65
T11058	1783-1794	Protein_catabolism	denotes	degradation
T11059	1802-1811	Protein	denotes	inhibitor
T11060	1812-1816	Protein	denotes	IκBα
T11061	1888-1892	Protein	denotes	IκBα
T11062	1893-1904	Protein_catabolism	denotes	degradation	true
T11063	1958-1962	Protein	denotes	IκBα
T11064	1976-1984	Protein_catabolism	denotes	degraded
T11065	2042-2046	Protein	denotes	IκBα
T11066	2065-2070	Negative_regulation	denotes	masks
T11067	2075-2104	Entity	denotes	nuclear localisation sequence
T11068	2108-2111	Protein	denotes	p65
T11069	2136-2144	Protein_catabolism	denotes	degraded
T18190	2340-2347	Positive_regulation	denotes	driving		true
T18191	2348-2358	Gene_expression	denotes	expression
T18192	2362-2372	Protein	denotes	luciferase
T18193	2693-2697	Protein	denotes	IκBα
T18194	3062-3065	Protein	denotes	p50
T18195	3075-3078	Protein	denotes	p50
T18196	3089-3092	Protein	denotes	p65
T18197	3102-3105	Protein	denotes	p65
T18198	3394-3397	Protein	denotes	p50
T18199	3415-3418	Protein	denotes	p65
R9542	T11037	T11042	themeOf	expression,controlled
R9543	T11038	T11041	themeOf	expression,controlled
R9544	T11039	T11038	themeOf	ICAM-1,expression
R9545	T11040	T11037	themeOf	TNF-α,expression
R9546	T11044	T11043	themeOf	luciferase,increase
R9547	T11048	T11046	themeOf	activation,induced
R9548	T11049	T11047	themeOf	activation,induced
R9549	T11050	T11049	themeOf	p50,activation
R9550	T11051	T11048	themeOf	p65,activation
R9551	T11054	T11053	themeOf	increase,induced
R9552	T11055	T11052	themeOf	increase,induced
R9553	T11056	T11055	themeOf	p50,increase
R9554	T11057	T11054	themeOf	p65,increase
R9555	T11060	T11058	themeOf	IκBα,degradation
R9556	T11061	T11062	themeOf	IκBα,degradation
R9557	T11063	T11064	themeOf	IκBα,degraded
R9558	T11065	T11066	causeOf	IκBα,masks
R9559	T11065	T11069	themeOf	IκBα,degraded
R9560	T11067	T11066	themeOf	nuclear localisation sequence,masks
R9561	T11067	T11068	partOf	nuclear localisation sequence,p65
R15548	T18191	T18190	themeOf	expression,driving
R15549	T18192	T18191	themeOf	luciferase,expression
R15550	T18195	T18194	equivalentTo	p50,p50
R15551	T18197	T18196	equivalentTo	p65,p65

bionlp-st-ge-2016-reference-tees

Id	Subject	Object	Predicate	Lexical cue
T11070	0-35	Protein	denotes	Degraded CGN Induce IκB Degradation
T11071	40-45	Protein	denotes	NF-κB
T11072	46-56	Positive_regulation	denotes	Activation
T11073	46-56	Positive_regulation	denotes	Activation
T11074	94-100	Protein	denotes	ICAM-1
T11075	105-110	Protein	denotes	TNF-α
T11076	132-152	Protein	denotes	nuclear factor NF-κB
T11077	61-71	Gene_expression	denotes	expression
T11078	61-71	Gene_expression	denotes	expression
T11079	114-124	Regulation	denotes	controlled
T11080	114-124	Regulation	denotes	controlled
T11081	201-204	Protein	denotes	IκB
T11082	285-290	Protein	denotes	NF-κB
T11083	168-183	Phosphorylation	denotes	phosphorylation
T11084	267-277	Positive_regulation	denotes	activation
T11085	329-334	Protein	denotes	NF-κB
T11086	405-410	Protein	denotes	NF-κB
T11087	443-453	Protein	denotes	luciferase
T11088	391-401	Positive_regulation	denotes	activation
T11089	431-439	Positive_regulation	denotes	increase
T11090	374-381	Positive_regulation	denotes	induced
T11091	506-511	Protein	denotes	NF-κB
T11092	512-522	Positive_regulation	denotes	activation
T11093	498-505	Positive_regulation	denotes	induced
T11094	686-691	Protein	denotes	NF-κB
T11095	676-685	Gene_expression	denotes	detecting
T11096	812-826	Protein	denotes	NF-κB subunits
T11097	832-841	Positive_regulation	denotes	activated
T11098	911-914	Protein	denotes	p50
T11099	919-931	Protein	denotes	p65 subunits
T11100	935-940	Protein	denotes	NF-κB
T11101	893-903	Positive_regulation	denotes	activation
T11102	885-892	Positive_regulation	denotes	induced
T11103	1147-1152	Protein	denotes	NF-κB
T11104	1154-1161	Protein	denotes	Fig. 7C
T11105	1133-1143	Positive_regulation	denotes	activation
T11106	1114-1121	Positive_regulation	denotes	induced
T11107	1429-1442	Protein	denotes	nuclear NF-κB
T11108	1444-1451	Protein	denotes	Fig. 7D
T11109	1522-1525	Protein	denotes	p50
T11110	1530-1542	Protein	denotes	p65 subunits
T11111	1546-1551	Protein	denotes	NF-κB
T11112	1506-1514	Positive_regulation	denotes	increase
T11113	1495-1502	Positive_regulation	denotes	induced
T11114	1635-1640	Protein	denotes	NF-κB
T11115	1642-1649	Protein	denotes	Fig. 7D
T11116	1623-1631	Positive_regulation	denotes	increase
T11117	1623-1631	Positive_regulation	denotes	increase
T11118	1701-1704	Protein	denotes	p50
T11119	1705-1708	Protein	denotes	p65
T11120	1716-1729	Protein	denotes	NF-κB isoform
T11121	1730-1739	Positive_regulation	denotes	activated
T11122	1730-1739	Positive_regulation	denotes	activated
T11123	1802-1816	Protein	denotes	inhibitor IκBα
T11124	1783-1794	Protein_catabolism	denotes	degradation
T11125	1888-1892	Protein	denotes	IκBα
T11126	1958-1962	Protein	denotes	IκBα
T11127	1893-1904	Protein_catabolism	denotes	degradation
T11128	1976-1984	Protein_catabolism	denotes	degraded
T11129	2042-2054	Protein	denotes	IκBα subunit
T11130	2108-2111	Protein	denotes	p65
T11131	2136-2144	Protein_catabolism	denotes	degraded
T18200	2232-2235	Protein	denotes	CGN
T18201	2250-2255	Protein	denotes	NF-kB
T18202	2223-2231	Protein_catabolism	denotes	Degraded
T18203	2236-2245	Positive_regulation	denotes	activated
T18204	2236-2245	Positive_regulation	denotes	activated
T18205	2317-2331	Protein	denotes	NF-κB reporter
T18206	2362-2372	Protein	denotes	luciferase
T18207	2348-2358	Gene_expression	denotes	expression
T18208	2693-2710	Protein	denotes	IκBα or α−tubulin
T18209	2785-2790	Protein	denotes	NF-κB
T18210	2771-2781	Positive_regulation	denotes	activation
T18211	2763-2770	Positive_regulation	denotes	induced
T18212	3056-3061	Protein	denotes	NF-κB
T18213	3062-3073	Protein	denotes	p50 subunit
T18214	3075-3078	Protein	denotes	p50
T18215	3083-3088	Protein	denotes	NF-κB
T18216	3089-3100	Protein	denotes	p65 subunit
T18217	3102-3105	Protein	denotes	p65
T18218	3151-3154	Protein	denotes	ERK
T18219	3318-3323	Protein	denotes	NF-κB
T18220	3304-3314	Positive_regulation	denotes	activation
T18221	3296-3303	Positive_regulation	denotes	induced
T18222	3388-3393	Protein	denotes	NF-κB
T18223	3394-3405	Protein	denotes	p50 subunit
T18224	3409-3414	Protein	denotes	NF-κB
T18225	3415-3418	Protein	denotes	p65
R9562	T11070	T11072	themeOf	Degraded CGN Induce IκB Degradation,Activation
R9563	T11071	T11073	themeOf	NF-κB,Activation
R9564	T11074	T11077	themeOf	ICAM-1,expression
R9565	T11075	T11078	themeOf	TNF-α,expression
R9566	T11076	T11079	causeOf	nuclear factor NF-κB,controlled
R9567	T11076	T11080	causeOf	nuclear factor NF-κB,controlled
R9568	T11077	T11079	themeOf	expression,controlled
R9569	T11078	T11080	themeOf	expression,controlled
R9570	T11081	T11083	themeOf	IκB,phosphorylation
R9571	T11082	T11084	themeOf	NF-κB,activation
R9572	T11086	T11088	themeOf	NF-κB,activation
R9573	T11087	T11089	themeOf	luciferase,increase
R9574	T11088	T11090	themeOf	activation,induced
R9575	T11091	T11092	themeOf	NF-κB,activation
R9576	T11092	T11093	themeOf	activation,induced
R9577	T11094	T11095	themeOf	NF-κB,detecting
R9578	T11096	T11097	themeOf	NF-κB subunits,activated
R9579	T11098	T11101	themeOf	p50,activation
R9580	T11101	T11102	themeOf	activation,induced
R9581	T11103	T11105	themeOf	NF-κB,activation
R9582	T11104	T11106	causeOf	Fig. 7C,induced
R9583	T11105	T11106	themeOf	activation,induced
R9584	T11109	T11112	themeOf	p50,increase
R9585	T11112	T11113	themeOf	increase,induced
R9586	T11114	T11116	themeOf	NF-κB,increase
R9587	T11115	T11117	themeOf	Fig. 7D,increase
R9588	T11118	T11121	themeOf	p50,activated
R9589	T11120	T11122	themeOf	NF-κB isoform,activated
R9590	T11123	T11124	themeOf	inhibitor IκBα,degradation
R9591	T11125	T11127	themeOf	IκBα,degradation
R9592	T11126	T11128	themeOf	IκBα,degraded
R9593	T11130	T11131	themeOf	p65,degraded
R15552	T18200	T18202	themeOf	CGN,Degraded
R15553	T18200	T18203	causeOf	CGN,activated
R15554	T18200	T18204	causeOf	CGN,activated
R15555	T18201	T18203	themeOf	NF-kB,activated
R15556	T18202	T18204	themeOf	Degraded,activated
R15557	T18206	T18207	themeOf	luciferase,expression
R15558	T18209	T18210	themeOf	NF-κB,activation
R15559	T18210	T18211	themeOf	activation,induced
R15560	T18219	T18220	themeOf	NF-κB,activation
R15561	T18220	T18221	themeOf	activation,induced

bionlp-st-ge-2016-reference

Id	Subject	Object	Predicate	Lexical cue	Negation	Speculation
T10028	61-71	Gene_expression	denotes	expression
T10029	61-71	Gene_expression	denotes	expression
T10030	94-100	Protein	denotes	ICAM-1
T10031	105-110	Protein	denotes	TNF-α
T10032	114-124	Regulation	denotes	controlled
T10033	114-124	Regulation	denotes	controlled
T10034	431-439	Positive_regulation	denotes	increase
T10035	443-453	Protein	denotes	luciferase
T10036	812-826	Protein	denotes	NF-κB subunits
T10037	885-892	Positive_regulation	denotes	induced
T10038	885-892	Positive_regulation	denotes	induced
T10039	893-903	Positive_regulation	denotes	activation
T10040	893-903	Positive_regulation	denotes	activation
T10041	911-914	Protein	denotes	p50
T10042	919-922	Protein	denotes	p65
T10043	1495-1502	Positive_regulation	denotes	induced
T10044	1495-1502	Positive_regulation	denotes	induced
T10045	1506-1514	Positive_regulation	denotes	increase
T10046	1506-1514	Positive_regulation	denotes	increase
T10047	1522-1525	Protein	denotes	p50
T10048	1530-1533	Protein	denotes	p65
T10049	1783-1794	Protein_catabolism	denotes	degradation
T10050	1802-1811	Protein	denotes	inhibitor
T10051	1812-1816	Protein	denotes	IκBα
T10052	1888-1892	Protein	denotes	IκBα
T10053	1893-1904	Protein_catabolism	denotes	degradation	true
T10054	1958-1962	Protein	denotes	IκBα
T10055	1976-1984	Protein_catabolism	denotes	degraded
T10056	2042-2046	Protein	denotes	IκBα
T10057	2065-2070	Negative_regulation	denotes	masks
T10058	2075-2104	Entity	denotes	nuclear localisation sequence
T10059	2108-2111	Protein	denotes	p65
T10060	2136-2144	Protein_catabolism	denotes	degraded
T17517	2340-2347	Positive_regulation	denotes	driving		true
T17518	2348-2358	Gene_expression	denotes	expression
T17519	2362-2372	Protein	denotes	luciferase
T17520	2693-2697	Protein	denotes	IκBα
T17521	3062-3065	Protein	denotes	p50
T17522	3075-3078	Protein	denotes	p50
T17523	3089-3092	Protein	denotes	p65
T17524	3102-3105	Protein	denotes	p65
T17525	3394-3397	Protein	denotes	p50
T17526	3415-3418	Protein	denotes	p65
R8670	T10028	T10033	themeOf	expression,controlled
R8671	T10029	T10032	themeOf	expression,controlled
R8672	T10030	T10029	themeOf	ICAM-1,expression
R8673	T10031	T10028	themeOf	TNF-α,expression
R8674	T10035	T10034	themeOf	luciferase,increase
R8675	T10039	T10037	themeOf	activation,induced
R8676	T10040	T10038	themeOf	activation,induced
R8677	T10041	T10040	themeOf	p50,activation
R8678	T10042	T10039	themeOf	p65,activation
R8679	T10045	T10044	themeOf	increase,induced
R8680	T10046	T10043	themeOf	increase,induced
R8681	T10047	T10046	themeOf	p50,increase
R8682	T10048	T10045	themeOf	p65,increase
R8683	T10051	T10049	themeOf	IκBα,degradation
R8684	T10052	T10053	themeOf	IκBα,degradation
R8685	T10054	T10055	themeOf	IκBα,degraded
R8686	T10056	T10057	causeOf	IκBα,masks
R8687	T10056	T10060	themeOf	IκBα,degraded
R8688	T10058	T10057	themeOf	nuclear localisation sequence,masks
R8689	T10058	T10059	partOf	nuclear localisation sequence,p65
R14948	T17518	T17517	themeOf	expression,driving
R14949	T17519	T17518	themeOf	luciferase,expression
R14950	T17522	T17521	equivalentTo	p50,p50
R14951	T17524	T17523	equivalentTo	p65,p65

bionlp-st-ge-2016-uniprot

Id	Subject	Object	Predicate	Lexical cue
T10479	94-100	P05362	denotes	ICAM-1
T10480	105-108	P01375	denotes	TNF
T10481	105-110	P01375	denotes	TNF-α
T10482	443-453	P08659	denotes	luciferase
T10483	911-914	P19838	denotes	p50
T10484	919-922	P21579	denotes	p65
T10485	919-922	Q04206	denotes	p65
T10486	1522-1525	P19838	denotes	p50
T10487	1530-1533	Q04206	denotes	p65
T10488	1530-1533	P21579	denotes	p65
T10489	1701-1704	P19838	denotes	p50
T10490	1705-1708	P21579	denotes	p65
T10491	1705-1708	Q04206	denotes	p65
T10492	1812-1816	P25963	denotes	IκBα
T10493	1888-1892	P25963	denotes	IκBα
T10494	1958-1962	P25963	denotes	IκBα
T10495	2042-2046	P25963	denotes	IκBα
T10496	2065-2070	Q8IWZ3	denotes	masks
T10497	2108-2111	Q04206	denotes	p65
T10498	2108-2111	P21579	denotes	p65
T17825	2362-2372	P08659	denotes	luciferase
T17826	2693-2697	P25963	denotes	IκBα
T17827	3062-3065	P19838	denotes	p50
T17828	3062-3073	P19838	denotes	p50 subunit
T17829	3075-3078	P19838	denotes	p50
T17830	3089-3092	P21579	denotes	p65
T17831	3089-3092	Q04206	denotes	p65
T17832	3102-3105	P21579	denotes	p65
T17833	3102-3105	Q04206	denotes	p65
T17834	3394-3397	P19838	denotes	p50
T17835	3394-3405	P19838	denotes	p50 subunit
T17836	3415-3418	Q04206	denotes	p65
T17837	3415-3418	P21579	denotes	p65

test2

Id	Subject	Object	Predicate	Lexical cue	Negation	Speculation
T10000	61-71	Gene_expression	denotes	expression
T10001	94-100	Protein	denotes	ICAM-1
T10002	105-110	Protein	denotes	TNF-α
T10003	114-124	Regulation	denotes	controlled
T10004	218-229	Protein_catabolism	denotes	degradation
T10005	431-439	Positive_regulation	denotes	increase
T10006	443-453	Protein	denotes	luciferase
T10007	589-596	Positive_regulation	denotes	induced
T10008	812-826	Protein	denotes	NF-κB subunits
T10009	885-892	Positive_regulation	denotes	induced
T10010	893-903	Positive_regulation	denotes	activation
T10011	911-914	Protein	denotes	p50
T10012	919-922	Protein	denotes	p65
T10013	1495-1502	Positive_regulation	denotes	induced
T10014	1506-1514	Positive_regulation	denotes	increase	true
T10015	1522-1525	Protein	denotes	p50
T10016	1530-1533	Protein	denotes	p65
T10017	1783-1794	Protein_catabolism	denotes	degradation
T10018	1802-1811	Protein	denotes	inhibitor
T10019	1812-1816	Protein	denotes	IκBα
T10020	1888-1892	Protein	denotes	IκBα
T10021	1893-1904	Protein_catabolism	denotes	degradation
T10022	1958-1962	Protein	denotes	IκBα
T10023	1976-1984	Protein_catabolism	denotes	degraded
T10024	2042-2046	Protein	denotes	IκBα
T10025	2075-2082	Entity	denotes	nuclear
T10026	2083-2095	Localization	denotes	localisation
T10027	2108-2111	Protein	denotes	p65
T17507	2340-2347	Positive_regulation	denotes	driving		true
T17508	2348-2358	Gene_expression	denotes	expression
T17509	2362-2372	Protein	denotes	luciferase
T17510	2693-2697	Protein	denotes	IκBα
T17511	3062-3065	Protein	denotes	p50
T17512	3075-3078	Protein	denotes	p50
T17513	3089-3092	Protein	denotes	p65
T17514	3102-3105	Protein	denotes	p65
T17515	3394-3397	Protein	denotes	p50
T17516	3415-3418	Protein	denotes	p65
R8656	T10000	T10003	themeOf	expression,controlled
R8657	T10001	T10000	themeOf	ICAM-1,expression
R8658	T10002	T10000	themeOf	TNF-α,expression
R8659	T10006	T10005	themeOf	luciferase,increase
R8660	T10010	T10009	themeOf	activation,induced
R8661	T10011	T10010	themeOf	p50,activation
R8662	T10012	T10010	themeOf	p65,activation
R8663	T10014	T10013	themeOf	increase,induced
R8664	T10015	T10014	themeOf	p50,increase
R8665	T10016	T10014	themeOf	p65,increase
R8666	T10019	T10018	themeOf	IκBα,inhibitor
R8667	T10019	T10017	themeOf	IκBα,degradation
R8668	T10020	T10021	themeOf	IκBα,degradation
R8669	T10022	T10023	themeOf	IκBα,degraded
R14944	T17508	T17507	themeOf	expression,driving
R14945	T17509	T17508	themeOf	luciferase,expression
R14946	T17512	T17511	equivalentTo	p50,p50
R14947	T17514	T17513	equivalentTo	p65,p65

PMC:2800179 / 25764-29489 JSONTXT

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PMC:2800179 / 25764-29489 JSON TXT