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{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/2792620","sourcedb":"PMC","sourceid":"2792620","source_url":"http://www.ncbi.nlm.nih.gov/pmc/2792620","text":"Prostaglandin analogs\nProstaglandins (PG) are known mediators of inflammation. At high doses, they can induce increased IOP. Conversely, at low doses prostaglandins have been shown to lower IOP.[44] Hypotensive lipids, named as eicosanoids, including latanoprost, travaprost and bimatoprost. Prostaglandin analogs [Figure 6] represent a novel class of topically active ocular hypotensive agents with a unique mechanism of action.\nFigure 6 Chemical structures of prostaglandin F2α and commercially available prostaglandin analogues\n\nL","divisions":[{"label":"Title","span":{"begin":0,"end":21}},{"label":"Figure caption","span":{"begin":430,"end":533}}],"tracks":[{"project":"2_test","denotations":[{"id":"20040958-10776828-47224464","span":{"begin":195,"end":197},"obj":"10776828"},{"id":"T83128","span":{"begin":195,"end":197},"obj":"10776828"}],"attributes":[{"subj":"20040958-10776828-47224464","pred":"source","obj":"2_test"},{"subj":"T83128","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#da93ec","default":true}]}]}}