PMC:2791889 / 5303-5529
Annnotations
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1181 | 49-54 | P22301 | denotes | IL-10 |
T1182 | 86-89 | P01730 | denotes | CD4 |
T1183 | 108-113 | P29459 | denotes | IL-12 |
T1184 | 108-113 | P29460 | denotes | IL-12 |
T1185 | 122-127 | Q14765 | denotes | STAT4 |
T1186 | 196-200 | P27361 | denotes | ERK1 |
T1187 | 205-209 | P28482 | denotes | ERK2 |
bionlp-st-ge-2016-reference
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1097 | 49-54 | Protein | denotes | IL-10 |
T1098 | 55-64 | Gene_expression | denotes | producing |
T1099 | 86-89 | Protein | denotes | CD4 |
T1100 | 108-113 | Protein | denotes | IL-12 |
T1101 | 122-127 | Protein | denotes | STAT4 |
T1102 | 196-200 | Protein | denotes | ERK1 |
T1103 | 205-209 | Protein | denotes | ERK2 |
T1104 | 210-225 | Phosphorylation | denotes | phosphorylation |
T1105 | 210-225 | Phosphorylation | denotes | phosphorylation |
R801 | T1097 | T1098 | themeOf | IL-10,producing |
R802 | T1102 | T1105 | themeOf | ERK1,phosphorylation |
R803 | T1103 | T1104 | themeOf | ERK2,phosphorylation |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2012 | 0-4 | RB | denotes | Here |
T2013 | 4-5 | , | denotes | , |
T2014 | 6-8 | PRP | denotes | we |
T2015 | 9-15 | VBD | denotes | showed |
T2016 | 16-20 | IN | denotes | that |
T2017 | 21-23 | IN | denotes | in |
T2018 | 24-29 | NN | denotes | vitro |
T2019 | 30-45 | NN | denotes | differentiation |
T2020 | 46-48 | IN | denotes | of |
T2021 | 49-64 | JJ | denotes | IL-10-producing |
T2022 | 65-68 | JJ | denotes | Th1 |
T2023 | 69-74 | NNS | denotes | cells |
T2024 | 75-79 | IN | denotes | from |
T2025 | 80-85 | JJ | denotes | naive |
T2026 | 86-89 | NNP | denotes | CD4 |
T2027 | 89-90 | CD | denotes | + |
T2028 | 91-92 | NNP | denotes | T |
T2029 | 93-98 | NNS | denotes | cells |
T2030 | 99-107 | VBN | denotes | required |
T2031 | 108-121 | JJ | denotes | IL-12-induced |
T2032 | 122-127 | CD | denotes | STAT4 |
T2033 | 128-137 | VBG | denotes | signaling |
T2034 | 137-138 | , | denotes | , |
T2035 | 139-145 | JJ | denotes | strong |
T2036 | 146-149 | NNP | denotes | TCR |
T2037 | 150-160 | NN | denotes | activation |
T2038 | 161-162 | -LRB- | denotes | ( |
T2039 | 162-166 | JJ | denotes | high |
T2040 | 167-174 | NN | denotes | antigen |
T2041 | 175-179 | NN | denotes | dose |
T2042 | 179-180 | -RRB- | denotes | ) |
T2043 | 180-181 | , | denotes | , |
T2044 | 182-185 | CC | denotes | and |
T2045 | 186-195 | VBD | denotes | sustained |
T2046 | 196-200 | CD | denotes | ERK1 |
T2047 | 201-204 | CC | denotes | and |
T2048 | 205-209 | CD | denotes | ERK2 |
T2049 | 210-225 | NN | denotes | phosphorylation |
T2050 | 225-226 | . | denotes | . |
R1603 | T2050 | T2015 | punct | .,showed |
R1642 | T2012 | T2015 | advmod | Here,showed |
R1643 | T2013 | T2015 | punct | ",",showed |
R1644 | T2014 | T2015 | nsubj | we,showed |
R1645 | T2015 | T2015 | ROOT | showed,showed |
R1647 | T2016 | T2030 | mark | that,required |
R1648 | T2017 | T2030 | prep | in,required |
R1649 | T2018 | T2019 | amod | vitro,differentiation |
R1650 | T2019 | T2017 | pobj | differentiation,in |
R1652 | T2020 | T2019 | prep | of,differentiation |
R1653 | T2021 | T2023 | amod | IL-10-producing,cells |
R1654 | T2022 | T2023 | amod | Th1,cells |
R1656 | T2023 | T2020 | pobj | cells,of |
R1657 | T2024 | T2023 | prep | from,cells |
R1659 | T2025 | T2029 | amod | naive,cells |
R1660 | T2026 | T2029 | compound | CD4,cells |
R1661 | T2027 | T2029 | nummod | +,cells |
R1663 | T2028 | T2029 | compound | T,cells |
R1664 | T2029 | T2024 | pobj | cells,from |
R1665 | T2030 | T2015 | ccomp | required,showed |
R1667 | T2031 | T2033 | npadvmod | IL-12-induced,signaling |
R1668 | T2032 | T2033 | nummod | STAT4,signaling |
R1669 | T2033 | T2030 | dobj | signaling,required |
R1670 | T2034 | T2033 | punct | ",",signaling |
R1672 | T2035 | T2037 | amod | strong,activation |
R1673 | T2036 | T2037 | compound | TCR,activation |
R1675 | T2037 | T2033 | appos | activation,signaling |
R1676 | T2038 | T2037 | punct | (,activation |
R1677 | T2039 | T2040 | amod | high,antigen |
R1679 | T2040 | T2041 | compound | antigen,dose |
R1680 | T2041 | T2037 | appos | dose,activation |
R1681 | T2042 | T2037 | punct | ),activation |
R1682 | T2043 | T2030 | punct | ",",required |
R1683 | T2044 | T2030 | cc | and,required |
R1684 | T2045 | T2030 | conj | sustained,required |
R1685 | T2046 | T2045 | dobj | ERK1,sustained |
R1687 | T2047 | T2046 | cc | and,ERK1 |
R1688 | T2048 | T2049 | nummod | ERK2,phosphorylation |
R1689 | T2049 | T2046 | conj | phosphorylation,ERK1 |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2138 | 146-149 | http://purl.obolibrary.org/obo/GO_0006283 | denotes | TCR |
T2176 | 196-200 | http://purl.obolibrary.org/obo/GO_0004707 | denotes | ERK1 |
T2178 | 205-209 | http://purl.obolibrary.org/obo/GO_0004707 | denotes | ERK2 |
T2185 | 210-225 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
T2159 | 128-137 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
GO-MF
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2200 | 49-54 | http://purl.obolibrary.org/obo/GO_0005141 | denotes | IL-10 |
T2207 | 108-113 | http://purl.obolibrary.org/obo/GO_0005143 | denotes | IL-12 |
T2220 | 196-200 | http://purl.obolibrary.org/obo/GO_0004707 | denotes | ERK1 |
T2222 | 205-209 | http://purl.obolibrary.org/obo/GO_0004707 | denotes | ERK2 |
GO-CC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2243 | 146-149 | http://purl.obolibrary.org/obo/GO_0042101 | denotes | TCR |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1131 | 0-226 | Sentence | denotes | Here, we showed that in vitro differentiation of IL-10-producing Th1 cells from naive CD4+ T cells required IL-12-induced STAT4 signaling, strong TCR activation (high antigen dose), and sustained ERK1 and ERK2 phosphorylation. |
T27 | 0-226 | Sentence | denotes | Here, we showed that in vitro differentiation of IL-10-producing Th1 cells from naive CD4+ T cells required IL-12-induced STAT4 signaling, strong TCR activation (high antigen dose), and sustained ERK1 and ERK2 phosphorylation. |
events-check-again
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2534 | 49-54 | Protein | denotes | IL-10 |
T2535 | 55-64 | Gene_expression | denotes | producing |
T2536 | 86-89 | Protein | denotes | CD4 |
T2537 | 108-113 | Protein | denotes | IL-12 |
T2538 | 122-127 | Protein | denotes | STAT4 |
T2539 | 196-200 | Protein | denotes | ERK1 |
T2540 | 205-209 | Protein | denotes | ERK2 |
T2541 | 210-225 | Phosphorylation | denotes | phosphorylation |
T2542 | 210-225 | Phosphorylation | denotes | phosphorylation |
R1952 | T2534 | T2535 | themeOf | IL-10,producing |
R1953 | T2539 | T2542 | themeOf | ERK1,phosphorylation |
R1954 | T2540 | T2541 | themeOf | ERK2,phosphorylation |
bionlp-st-ge-2016-reference-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2635 | 86-90 | Protein | denotes | CD4+ |
T2636 | 122-127 | Protein | denotes | STAT4 |
T2637 | 146-149 | Protein | denotes | TCR |
T2638 | 196-200 | Protein | denotes | ERK1 |
T2639 | 205-209 | Protein | denotes | ERK2 |
T2640 | 210-225 | Phosphorylation | denotes | phosphorylation |
T2641 | 210-225 | Phosphorylation | denotes | phosphorylation |
T2642 | 150-160 | Positive_regulation | denotes | activation |
T2643 | 150-160 | Positive_regulation | denotes | activation |
R1996 | T2638 | T2640 | themeOf | ERK1,phosphorylation |
R1997 | T2639 | T2641 | themeOf | ERK2,phosphorylation |
R1998 | T2640 | T2642 | themeOf | phosphorylation,activation |
R1999 | T2641 | T2643 | themeOf | phosphorylation,activation |
test2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T993 | 49-54 | Protein | denotes | IL-10 |
T994 | 55-64 | Gene_expression | denotes | producing |
T995 | 86-89 | Protein | denotes | CD4 |
T996 | 99-107 | Positive_regulation | denotes | required |
T997 | 108-113 | Protein | denotes | IL-12 |
T998 | 114-121 | Positive_regulation | denotes | induced |
T999 | 122-127 | Protein | denotes | STAT4 |
T1000 | 186-195 | Positive_regulation | denotes | sustained |
T1001 | 196-200 | Protein | denotes | ERK1 |
T1002 | 205-209 | Protein | denotes | ERK2 |
T1003 | 210-225 | Phosphorylation | denotes | phosphorylation |
R728 | T993 | T994 | themeOf | IL-10,producing |
R729 | T997 | T998 | causeOf | IL-12,induced |
R730 | T998 | T996 | themeOf | induced,required |
R731 | T1001 | T1003 | themeOf | ERK1,phosphorylation |
R732 | T1002 | T1003 | themeOf | ERK2,phosphorylation |
R733 | T1003 | T1000 | themeOf | phosphorylation,sustained |