PMC:2791889 / 29201-29505 JSONTXT

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{"project":"GO-MF","denotations":[{"id":"T17620","span":{"begin":35,"end":40},"obj":"http://purl.obolibrary.org/obo/GO_0005141"},{"id":"T17621","span":{"begin":86,"end":91},"obj":"http://purl.obolibrary.org/obo/GO_0005141"},{"id":"T17622","span":{"begin":253,"end":258},"obj":"http://purl.obolibrary.org/obo/GO_0005141"},{"id":"T17639","span":{"begin":109,"end":112},"obj":"http://purl.obolibrary.org/obo/GO_0004707"}],"text":"That c-maf expression is common to IL-10-producing Th1, Th2, and Th17 cells and, like IL-10, is dependent on ERK activation in Th1 and Th17 cells for its expression is of interest because c-Maf has been shown to be an essential transcription factor for IL-10 expression in macrophages (Cao et al., 2005)."}

{"project":"GO-CC","denotations":[{"id":"T17701","span":{"begin":70,"end":75},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T17702","span":{"begin":140,"end":145},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"That c-maf expression is common to IL-10-producing Th1, Th2, and Th17 cells and, like IL-10, is dependent on ERK activation in Th1 and Th17 cells for its expression is of interest because c-Maf has been shown to be an essential transcription factor for IL-10 expression in macrophages (Cao et al., 2005)."}

{"project":"sentences","denotations":[{"id":"T14227","span":{"begin":0,"end":304},"obj":"Sentence"},{"id":"T149","span":{"begin":0,"end":304},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"That c-maf expression is common to IL-10-producing Th1, Th2, and Th17 cells and, like IL-10, is dependent on ERK activation in Th1 and Th17 cells for its expression is of interest because c-Maf has been shown to be an essential transcription factor for IL-10 expression in macrophages (Cao et al., 2005)."}

{"project":"events-check-again","denotations":[{"id":"T18385","span":{"begin":5,"end":10},"obj":"Protein"},{"id":"T18386","span":{"begin":11,"end":21},"obj":"Gene_expression"},{"id":"T18387","span":{"begin":35,"end":40},"obj":"Protein"},{"id":"T18388","span":{"begin":41,"end":50},"obj":"Gene_expression"},{"id":"T18389","span":{"begin":86,"end":91},"obj":"Protein"},{"id":"T18390","span":{"begin":96,"end":105},"obj":"Positive_regulation"},{"id":"T18391","span":{"begin":96,"end":105},"obj":"Positive_regulation"},{"id":"T18392","span":{"begin":109,"end":112},"obj":"Protein"},{"id":"T18393","span":{"begin":113,"end":123},"obj":"Positive_regulation"},{"id":"T18394","span":{"begin":154,"end":164},"obj":"Gene_expression"},{"id":"T18395","span":{"begin":188,"end":193},"obj":"Protein"},{"id":"T18396","span":{"begin":218,"end":227},"obj":"Positive_regulation"},{"id":"T18397","span":{"begin":253,"end":258},"obj":"Protein"},{"id":"T18398","span":{"begin":259,"end":269},"obj":"Gene_expression"}],"relations":[{"id":"R14672","pred":"themeOf","subj":"T18385","obj":"T18386"},{"id":"R14674","pred":"themeOf","subj":"T18385","obj":"T18394"},{"id":"R14677","pred":"themeOf","subj":"T18386","obj":"T18391"},{"id":"R14679","pred":"themeOf","subj":"T18387","obj":"T18388"},{"id":"R14682","pred":"themeOf","subj":"T18389","obj":"T18390"},{"id":"R14684","pred":"themeOf","subj":"T18392","obj":"T18393"},{"id":"R14690","pred":"causeOf","subj":"T18393","obj":"T18391"},{"id":"R14695","pred":"causeOf","subj":"T18393","obj":"T18390"},{"id":"R14697","pred":"causeOf","subj":"T18395","obj":"T18396"},{"id":"R14700","pred":"themeOf","subj":"T18397","obj":"T18398"},{"id":"R14702","pred":"themeOf","subj":"T18398","obj":"T18396"}],"text":"That c-maf expression is common to IL-10-producing Th1, Th2, and Th17 cells and, like IL-10, is dependent on ERK activation in Th1 and Th17 cells for its expression is of interest because c-Maf has been shown to be an essential transcription factor for IL-10 expression in macrophages (Cao et al., 2005)."}

{"project":"bionlp-st-ge-2016-reference-tees","denotations":[{"id":"T18608","span":{"begin":86,"end":91},"obj":"Protein"},{"id":"T18609","span":{"begin":109,"end":112},"obj":"Protein"},{"id":"T18610","span":{"begin":188,"end":193},"obj":"Protein"},{"id":"T18611","span":{"begin":253,"end":258},"obj":"Protein"},{"id":"T18612","span":{"begin":113,"end":123},"obj":"Positive_regulation"},{"id":"T18613","span":{"begin":259,"end":269},"obj":"Gene_expression"},{"id":"T18614","span":{"begin":96,"end":105},"obj":"Positive_regulation"}],"relations":[{"id":"R14720","pred":"themeOf","subj":"T18609","obj":"T18612"},{"id":"R14724","pred":"themeOf","subj":"T18611","obj":"T18613"},{"id":"R14728","pred":"themeOf","subj":"T18612","obj":"T18614"}],"text":"That c-maf expression is common to IL-10-producing Th1, Th2, and Th17 cells and, like IL-10, is dependent on ERK activation in Th1 and Th17 cells for its expression is of interest because c-Maf has been shown to be an essential transcription factor for IL-10 expression in macrophages (Cao et al., 2005)."}

{"project":"test2","denotations":[{"id":"T13913","span":{"begin":5,"end":10},"obj":"Protein"},{"id":"T13914","span":{"begin":11,"end":21},"obj":"Gene_expression"},{"id":"T13915","span":{"begin":35,"end":40},"obj":"Protein"},{"id":"T13916","span":{"begin":41,"end":50},"obj":"Gene_expression"},{"id":"T13917","span":{"begin":86,"end":91},"obj":"Protein"},{"id":"T13918","span":{"begin":96,"end":105},"obj":"Positive_regulation"},{"id":"T13919","span":{"begin":109,"end":112},"obj":"Protein"},{"id":"T13920","span":{"begin":113,"end":123},"obj":"Positive_regulation"},{"id":"T13921","span":{"begin":154,"end":164},"obj":"Gene_expression"},{"id":"T13922","span":{"begin":188,"end":193},"obj":"Protein"},{"id":"T13923","span":{"begin":253,"end":258},"obj":"Protein"},{"id":"T13924","span":{"begin":259,"end":269},"obj":"Gene_expression"}],"relations":[{"id":"R10811","pred":"themeOf","subj":"T13917","obj":"T13921"},{"id":"R10807","pred":"themeOf","subj":"T13913","obj":"T13914"},{"id":"R10808","pred":"themeOf","subj":"T13913","obj":"T13921"},{"id":"R10809","pred":"themeOf","subj":"T13914","obj":"T13918"},{"id":"R10810","pred":"themeOf","subj":"T13915","obj":"T13916"},{"id":"R10812","pred":"themeOf","subj":"T13917","obj":"T13918"},{"id":"R10813","pred":"themeOf","subj":"T13919","obj":"T13920"},{"id":"R10814","pred":"causeOf","subj":"T13920","obj":"T13918"},{"id":"R10815","pred":"themeOf","subj":"T13923","obj":"T13924"}],"text":"That c-maf expression is common to IL-10-producing Th1, Th2, and Th17 cells and, like IL-10, is dependent on ERK activation in Th1 and Th17 cells for its expression is of interest because c-Maf has been shown to be an essential transcription factor for IL-10 expression in macrophages (Cao et al., 2005)."}