PMC:2791889 / 12736-12977 JSONTXT

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T7283","span":{"begin":20,"end":25},"obj":"Q14765"},{"id":"T7284","span":{"begin":30,"end":35},"obj":"P42226"},{"id":"T7285","span":{"begin":76,"end":81},"obj":"P22301"},{"id":"T7286","span":{"begin":118,"end":123},"obj":"Q14765"},{"id":"T7287","span":{"begin":128,"end":133},"obj":"P42226"},{"id":"T7288","span":{"begin":210,"end":213},"obj":"E2RVI8"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"To test the role of STAT4 and STAT6 signaling in the in vivo development of IL-10-producing Th1 cells, we transferred STAT4- or STAT6-deficient or WT DO11.10 cells into recipient BALB/c mice and immunized with OVA-protein plus LPS as before."}

{"project":"bionlp-st-ge-2016-reference","denotations":[{"id":"T7011","span":{"begin":20,"end":25},"obj":"Protein"},{"id":"T7012","span":{"begin":30,"end":35},"obj":"Protein"},{"id":"T7013","span":{"begin":76,"end":81},"obj":"Protein"},{"id":"T7014","span":{"begin":82,"end":91},"obj":"Gene_expression"},{"id":"T7015","span":{"begin":118,"end":123},"obj":"Protein"},{"id":"T7016","span":{"begin":128,"end":133},"obj":"Protein"},{"id":"T7017","span":{"begin":134,"end":143},"obj":"Negative_regulation"},{"id":"T7018","span":{"begin":134,"end":143},"obj":"Negative_regulation"},{"id":"T7019","span":{"begin":210,"end":213},"obj":"Protein"}],"relations":[{"id":"R5310","pred":"themeOf","subj":"T7013","obj":"T7014"},{"id":"R5311","pred":"themeOf","subj":"T7015","obj":"T7017"},{"id":"R5312","pred":"themeOf","subj":"T7016","obj":"T7018"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"To test the role of STAT4 and STAT6 signaling in the in vivo development of IL-10-producing Th1 cells, we transferred STAT4- or STAT6-deficient or WT DO11.10 cells into recipient BALB/c mice and immunized with OVA-protein plus LPS as before."}

{"project":"pmc-enju-pas","denotations":[{"id":"T7161","span":{"begin":0,"end":2},"obj":"TO"},{"id":"T7162","span":{"begin":3,"end":7},"obj":"VB"},{"id":"T7163","span":{"begin":8,"end":11},"obj":"DT"},{"id":"T7164","span":{"begin":12,"end":16},"obj":"NN"},{"id":"T7165","span":{"begin":17,"end":19},"obj":"IN"},{"id":"T7166","span":{"begin":20,"end":25},"obj":"NN"},{"id":"T7167","span":{"begin":26,"end":29},"obj":"CC"},{"id":"T7168","span":{"begin":30,"end":35},"obj":"NN"},{"id":"T7169","span":{"begin":36,"end":45},"obj":"NN"},{"id":"T7170","span":{"begin":46,"end":48},"obj":"IN"},{"id":"T7171","span":{"begin":49,"end":52},"obj":"DT"},{"id":"T7172","span":{"begin":53,"end":60},"obj":"FW"},{"id":"T7173","span":{"begin":61,"end":72},"obj":"NN"},{"id":"T7174","span":{"begin":73,"end":75},"obj":"IN"},{"id":"T7175","span":{"begin":76,"end":91},"obj":"JJ"},{"id":"T7176","span":{"begin":92,"end":95},"obj":"NN"},{"id":"T7177","span":{"begin":96,"end":101},"obj":"NN"},{"id":"T7178","span":{"begin":101,"end":102},"obj":"-COMMA-"},{"id":"T7179","span":{"begin":103,"end":105},"obj":"PRP"},{"id":"T7180","span":{"begin":106,"end":117},"obj":"VB"},{"id":"T7181","span":{"begin":118,"end":124},"obj":"NN"},{"id":"T7182","span":{"begin":125,"end":127},"obj":"CC"},{"id":"T7183","span":{"begin":128,"end":143},"obj":"JJ"},{"id":"T7184","span":{"begin":144,"end":146},"obj":"CC"},{"id":"T7185","span":{"begin":147,"end":149},"obj":"JJ"},{"id":"T7186","span":{"begin":150,"end":157},"obj":"NN"},{"id":"T7187","span":{"begin":158,"end":163},"obj":"NN"},{"id":"T7188","span":{"begin":164,"end":168},"obj":"IN"},{"id":"T7189","span":{"begin":169,"end":178},"obj":"JJ"},{"id":"T7190","span":{"begin":179,"end":185},"obj":"NN"},{"id":"T7191","span":{"begin":186,"end":190},"obj":"NN"},{"id":"T7192","span":{"begin":191,"end":194},"obj":"CC"},{"id":"T7193","span":{"begin":195,"end":204},"obj":"VB"},{"id":"T7194","span":{"begin":205,"end":209},"obj":"IN"},{"id":"T7195","span":{"begin":210,"end":221},"obj":"NN"},{"id":"T7196","span":{"begin":222,"end":226},"obj":"CC"},{"id":"T7197","span":{"begin":227,"end":230},"obj":"NN"},{"id":"T7198","span":{"begin":231,"end":233},"obj":"IN"},{"id":"T7199","span":{"begin":234,"end":240},"obj":"RB"}],"relations":[{"id":"R5447","pred":"arg1Of","subj":"T7162","obj":"T7161"},{"id":"R5448","pred":"arg2Of","subj":"T7164","obj":"T7162"},{"id":"R5449","pred":"arg1Of","subj":"T7164","obj":"T7163"},{"id":"R5450","pred":"arg1Of","subj":"T7164","obj":"T7165"},{"id":"R5451","pred":"arg1Of","subj":"T7164","obj":"T7170"},{"id":"R5452","pred":"arg1Of","subj":"T7166","obj":"T7167"},{"id":"R5453","pred":"arg2Of","subj":"T7168","obj":"T7167"},{"id":"R5454","pred":"arg2Of","subj":"T7169","obj":"T7165"},{"id":"R5455","pred":"arg1Of","subj":"T7169","obj":"T7166"},{"id":"R5456","pred":"arg1Of","subj":"T7169","obj":"T7168"},{"id":"R5457","pred":"arg2Of","subj":"T7173","obj":"T7170"},{"id":"R5458","pred":"arg1Of","subj":"T7173","obj":"T7171"},{"id":"R5459","pred":"arg1Of","subj":"T7173","obj":"T7172"},{"id":"R5460","pred":"arg1Of","subj":"T7173","obj":"T7174"},{"id":"R5461","pred":"arg2Of","subj":"T7177","obj":"T7174"},{"id":"R5462","pred":"arg1Of","subj":"T7177","obj":"T7175"},{"id":"R5463","pred":"arg1Of","subj":"T7177","obj":"T7176"},{"id":"R5464","pred":"arg1Of","subj":"T7179","obj":"T7162"},{"id":"R5465","pred":"arg1Of","subj":"T7179","obj":"T7180"},{"id":"R5466","pred":"modOf","subj":"T7180","obj":"T7161"},{"id":"R5467","pred":"arg1Of","subj":"T7180","obj":"T7178"},{"id":"R5468","pred":"arg1Of","subj":"T7181","obj":"T7182"},{"id":"R5469","pred":"arg2Of","subj":"T7182","obj":"T7180"},{"id":"R5470","pred":"arg1Of","subj":"T7183","obj":"T7184"},{"id":"R5471","pred":"arg2Of","subj":"T7185","obj":"T7184"},{"id":"R5472","pred":"arg2Of","subj":"T7187","obj":"T7182"},{"id":"R5473","pred":"arg1Of","subj":"T7187","obj":"T7183"},{"id":"R5474","pred":"arg1Of","subj":"T7187","obj":"T7185"},{"id":"R5475","pred":"arg1Of","subj":"T7187","obj":"T7186"},{"id":"R5476","pred":"arg1Of","subj":"T7187","obj":"T7188"},{"id":"R5477","pred":"arg2Of","subj":"T7187","obj":"T7193"},{"id":"R5478","pred":"arg1Of","subj":"T7188","obj":"T7192"},{"id":"R5479","pred":"arg2Of","subj":"T7191","obj":"T7188"},{"id":"R5480","pred":"arg1Of","subj":"T7191","obj":"T7189"},{"id":"R5481","pred":"arg1Of","subj":"T7191","obj":"T7190"},{"id":"R5482","pred":"arg2Of","subj":"T7193","obj":"T7192"},{"id":"R5483","pred":"arg1Of","subj":"T7193","obj":"T7194"},{"id":"R5484","pred":"arg1Of","subj":"T7194","obj":"T7199"},{"id":"R5485","pred":"arg1Of","subj":"T7195","obj":"T7196"},{"id":"R5486","pred":"arg2Of","subj":"T7196","obj":"T7194"},{"id":"R5487","pred":"arg2Of","subj":"T7197","obj":"T7196"},{"id":"R5488","pred":"arg1Of","subj":"T7199","obj":"T7198"}],"namespaces":[{"prefix":"_base","uri":"http://kmcs.nii.ac.jp/enju/"}],"text":"To test the role of STAT4 and STAT6 signaling in the in vivo development of IL-10-producing Th1 cells, we transferred STAT4- or STAT6-deficient or WT DO11.10 cells into recipient BALB/c mice and immunized with OVA-protein plus LPS as before."}

{"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T7423","span":{"begin":0,"end":2},"obj":"TO"},{"id":"T7424","span":{"begin":3,"end":7},"obj":"VB"},{"id":"T7425","span":{"begin":8,"end":11},"obj":"DT"},{"id":"T7426","span":{"begin":12,"end":16},"obj":"NN"},{"id":"T7427","span":{"begin":17,"end":19},"obj":"IN"},{"id":"T7428","span":{"begin":20,"end":25},"obj":"NNP"},{"id":"T7429","span":{"begin":26,"end":29},"obj":"CC"},{"id":"T7430","span":{"begin":30,"end":35},"obj":"NNP"},{"id":"T7431","span":{"begin":36,"end":45},"obj":"VBG"},{"id":"T7432","span":{"begin":46,"end":48},"obj":"IN"},{"id":"T7433","span":{"begin":49,"end":52},"obj":"DT"},{"id":"T7434","span":{"begin":53,"end":55},"obj":"IN"},{"id":"T7435","span":{"begin":56,"end":60},"obj":"NN"},{"id":"T7436","span":{"begin":61,"end":72},"obj":"NN"},{"id":"T7437","span":{"begin":73,"end":75},"obj":"IN"},{"id":"T7438","span":{"begin":76,"end":91},"obj":"JJ"},{"id":"T7439","span":{"begin":92,"end":95},"obj":"JJ"},{"id":"T7440","span":{"begin":96,"end":101},"obj":"NNS"},{"id":"T7441","span":{"begin":101,"end":102},"obj":","},{"id":"T7442","span":{"begin":103,"end":105},"obj":"PRP"},{"id":"T7443","span":{"begin":106,"end":117},"obj":"VBD"},{"id":"T7444","span":{"begin":118,"end":123},"obj":"NNP"},{"id":"T7445","span":{"begin":123,"end":124},"obj":":"},{"id":"T7446","span":{"begin":125,"end":127},"obj":"CC"},{"id":"T7447","span":{"begin":128,"end":143},"obj":"JJ"},{"id":"T7448","span":{"begin":144,"end":146},"obj":"CC"},{"id":"T7449","span":{"begin":147,"end":149},"obj":"NNP"},{"id":"T7450","span":{"begin":150,"end":154},"obj":"NNP"},{"id":"T7451","span":{"begin":154,"end":157},"obj":"CD"},{"id":"T7452","span":{"begin":158,"end":163},"obj":"NNS"},{"id":"T7453","span":{"begin":164,"end":168},"obj":"IN"},{"id":"T7454","span":{"begin":169,"end":178},"obj":"JJ"},{"id":"T7455","span":{"begin":179,"end":185},"obj":"NNP"},{"id":"T7456","span":{"begin":186,"end":190},"obj":"NNS"},{"id":"T7457","span":{"begin":191,"end":194},"obj":"CC"},{"id":"T7458","span":{"begin":195,"end":204},"obj":"VBN"},{"id":"T7459","span":{"begin":205,"end":209},"obj":"IN"},{"id":"T7460","span":{"begin":210,"end":221},"obj":"JJ"},{"id":"T7461","span":{"begin":222,"end":226},"obj":"CC"},{"id":"T7462","span":{"begin":227,"end":230},"obj":"NNP"},{"id":"T7463","span":{"begin":231,"end":233},"obj":"IN"},{"id":"T7464","span":{"begin":234,"end":240},"obj":"RB"},{"id":"T7465","span":{"begin":240,"end":241},"obj":"."}],"relations":[{"id":"R5693","pred":"aux","subj":"T7423","obj":"T7424"},{"id":"R5694","pred":"advcl","subj":"T7424","obj":"T7443"},{"id":"R5695","pred":"det","subj":"T7425","obj":"T7426"},{"id":"R5696","pred":"dobj","subj":"T7426","obj":"T7424"},{"id":"R5697","pred":"prep","subj":"T7427","obj":"T7426"},{"id":"R5698","pred":"pobj","subj":"T7428","obj":"T7427"},{"id":"R5699","pred":"cc","subj":"T7429","obj":"T7428"},{"id":"R5700","pred":"conj","subj":"T7430","obj":"T7428"},{"id":"R5701","pred":"acl","subj":"T7431","obj":"T7426"},{"id":"R5702","pred":"prep","subj":"T7432","obj":"T7431"},{"id":"R5703","pred":"det","subj":"T7433","obj":"T7436"},{"id":"R5704","pred":"nmod","subj":"T7434","obj":"T7436"},{"id":"R5705","pred":"compound","subj":"T7435","obj":"T7436"},{"id":"R5706","pred":"pobj","subj":"T7436","obj":"T7432"},{"id":"R5707","pred":"prep","subj":"T7437","obj":"T7436"},{"id":"R5708","pred":"amod","subj":"T7438","obj":"T7440"},{"id":"R5709","pred":"amod","subj":"T7439","obj":"T7440"},{"id":"R5710","pred":"pobj","subj":"T7440","obj":"T7437"},{"id":"R5711","pred":"punct","subj":"T7441","obj":"T7443"},{"id":"R5712","pred":"nsubj","subj":"T7442","obj":"T7443"},{"id":"R5713","pred":"ROOT","subj":"T7443","obj":"T7443"},{"id":"R5714","pred":"dobj","subj":"T7444","obj":"T7443"},{"id":"R5715","pred":"punct","subj":"T7445","obj":"T7444"},{"id":"R5716","pred":"cc","subj":"T7446","obj":"T7444"},{"id":"R5717","pred":"conj","subj":"T7447","obj":"T7444"},{"id":"R5718","pred":"cc","subj":"T7448","obj":"T7447"},{"id":"R5719","pred":"conj","subj":"T7449","obj":"T7447"},{"id":"R5720","pred":"conj","subj":"T7450","obj":"T7447"},{"id":"R5721","pred":"nummod","subj":"T7451","obj":"T7452"},{"id":"R5722","pred":"dobj","subj":"T7452","obj":"T7443"},{"id":"R5723","pred":"prep","subj":"T7453","obj":"T7443"},{"id":"R5724","pred":"compound","subj":"T7454","obj":"T7456"},{"id":"R5725","pred":"compound","subj":"T7455","obj":"T7456"},{"id":"R5726","pred":"pobj","subj":"T7456","obj":"T7453"},{"id":"R5727","pred":"cc","subj":"T7457","obj":"T7443"},{"id":"R5728","pred":"conj","subj":"T7458","obj":"T7443"},{"id":"R5729","pred":"prep","subj":"T7459","obj":"T7458"},{"id":"R5730","pred":"pobj","subj":"T7460","obj":"T7459"},{"id":"R5731","pred":"cc","subj":"T7461","obj":"T7460"},{"id":"R5732","pred":"conj","subj":"T7462","obj":"T7460"},{"id":"R5733","pred":"prep","subj":"T7463","obj":"T7460"},{"id":"R5734","pred":"pcomp","subj":"T7464","obj":"T7463"},{"id":"R5735","pred":"punct","subj":"T7465","obj":"T7443"}],"text":"To test the role of STAT4 and STAT6 signaling in the in vivo development of IL-10-producing Th1 cells, we transferred STAT4- or STAT6-deficient or WT DO11.10 cells into recipient BALB/c mice and immunized with OVA-protein plus LPS as before."}

{"project":"GO-BP","denotations":[{"id":"T7557","span":{"begin":36,"end":45},"obj":"http://purl.obolibrary.org/obo/GO_0023052"},{"id":"T7559","span":{"begin":61,"end":72},"obj":"http://purl.obolibrary.org/obo/GO_0032502"}],"text":"To test the role of STAT4 and STAT6 signaling in the in vivo development of IL-10-producing Th1 cells, we transferred STAT4- or STAT6-deficient or WT DO11.10 cells into recipient BALB/c mice and immunized with OVA-protein plus LPS as before."}

{"project":"GO-MF","denotations":[{"id":"T7564","span":{"begin":76,"end":81},"obj":"http://purl.obolibrary.org/obo/GO_0005141"}],"text":"To test the role of STAT4 and STAT6 signaling in the in vivo development of IL-10-producing Th1 cells, we transferred STAT4- or STAT6-deficient or WT DO11.10 cells into recipient BALB/c mice and immunized with OVA-protein plus LPS as before."}

{"project":"GO-CC","denotations":[{"id":"T7570","span":{"begin":96,"end":101},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T7571","span":{"begin":158,"end":163},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"To test the role of STAT4 and STAT6 signaling in the in vivo development of IL-10-producing Th1 cells, we transferred STAT4- or STAT6-deficient or WT DO11.10 cells into recipient BALB/c mice and immunized with OVA-protein plus LPS as before."}

{"project":"sentences","denotations":[{"id":"T7039","span":{"begin":0,"end":241},"obj":"Sentence"},{"id":"T67","span":{"begin":0,"end":241},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"To test the role of STAT4 and STAT6 signaling in the in vivo development of IL-10-producing Th1 cells, we transferred STAT4- or STAT6-deficient or WT DO11.10 cells into recipient BALB/c mice and immunized with OVA-protein plus LPS as before."}

{"project":"events-check-again","denotations":[{"id":"T7677","span":{"begin":20,"end":25},"obj":"Protein"},{"id":"T7678","span":{"begin":30,"end":35},"obj":"Protein"},{"id":"T7679","span":{"begin":76,"end":81},"obj":"Protein"},{"id":"T7680","span":{"begin":82,"end":91},"obj":"Gene_expression"},{"id":"T7681","span":{"begin":118,"end":123},"obj":"Protein"},{"id":"T7682","span":{"begin":128,"end":133},"obj":"Protein"},{"id":"T7683","span":{"begin":134,"end":143},"obj":"Negative_regulation"},{"id":"T7684","span":{"begin":134,"end":143},"obj":"Negative_regulation"},{"id":"T7685","span":{"begin":210,"end":213},"obj":"Protein"}],"relations":[{"id":"R5868","pred":"themeOf","subj":"T7679","obj":"T7680"},{"id":"R5869","pred":"themeOf","subj":"T7681","obj":"T7683"},{"id":"R5870","pred":"themeOf","subj":"T7682","obj":"T7684"}],"text":"To test the role of STAT4 and STAT6 signaling in the in vivo development of IL-10-producing Th1 cells, we transferred STAT4- or STAT6-deficient or WT DO11.10 cells into recipient BALB/c mice and immunized with OVA-protein plus LPS as before."}

{"project":"bionlp-st-ge-2016-reference-tees","denotations":[{"id":"T7712","span":{"begin":20,"end":25},"obj":"Protein"},{"id":"T7713","span":{"begin":30,"end":35},"obj":"Protein"},{"id":"T7714","span":{"begin":118,"end":123},"obj":"Protein"},{"id":"T7715","span":{"begin":128,"end":133},"obj":"Protein"},{"id":"T7716","span":{"begin":134,"end":143},"obj":"Negative_regulation"}],"relations":[{"id":"R5886","pred":"themeOf","subj":"T7715","obj":"T7716"}],"text":"To test the role of STAT4 and STAT6 signaling in the in vivo development of IL-10-producing Th1 cells, we transferred STAT4- or STAT6-deficient or WT DO11.10 cells into recipient BALB/c mice and immunized with OVA-protein plus LPS as before."}

{"project":"test2","denotations":[{"id":"T6969","span":{"begin":20,"end":25},"obj":"Protein"},{"id":"T6970","span":{"begin":30,"end":35},"obj":"Protein"},{"id":"T6971","span":{"begin":76,"end":81},"obj":"Protein"},{"id":"T6972","span":{"begin":82,"end":91},"obj":"Gene_expression"},{"id":"T6973","span":{"begin":118,"end":123},"obj":"Protein"},{"id":"T6974","span":{"begin":128,"end":133},"obj":"Protein"},{"id":"T6975","span":{"begin":134,"end":143},"obj":"Negative_regulation"},{"id":"T6976","span":{"begin":210,"end":213},"obj":"Protein"}],"relations":[{"id":"R5288","pred":"themeOf","subj":"T6971","obj":"T6972"},{"id":"R5289","pred":"themeOf","subj":"T6973","obj":"T6975"},{"id":"R5290","pred":"themeOf","subj":"T6974","obj":"T6975"}],"attributes":[{"id":"M120","pred":"Negation","subj":"T6970","obj":"true"},{"id":"M119","pred":"Negation","subj":"T6969","obj":"true"}],"text":"To test the role of STAT4 and STAT6 signaling in the in vivo development of IL-10-producing Th1 cells, we transferred STAT4- or STAT6-deficient or WT DO11.10 cells into recipient BALB/c mice and immunized with OVA-protein plus LPS as before."}