PMC:2728246 / 4541-5311
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2728246","sourcedb":"PMC","sourceid":"2728246","source_url":"https://www.ncbi.nlm.nih.gov/pmc/2728246","text":"Nevertheless, successful observations of supra-τc motions in side chains were possible by directly measuring the dynamic averaging of NMR interaction observables. The reduction of 13C–1H dipolar couplings in side chains were measured using solid-state NMR approaches in aggregated proteins (ubiquitin and Pf1 coat protein) and revealed motions faster than the μs time scale (Lorieau and McDermott 2006; Lorieau et al. 2008). Also, side chain rotameric interconversions up to ms were suggested based on residual dipolar couplings (RDC) measured in the side chains (Mittermaier and Kay 2001). In related fashion, using a combined approach of J-coupling and RDC measurements, a description of χ1 rotamer dynamics for protein G and ubiquitin was possible (Chou et al. 2003).","tracks":[{"project":"2_test","denotations":[{"id":"19652920-16939274-56190922","span":{"begin":397,"end":401},"obj":"16939274"},{"id":"19652920-18653759-56190923","span":{"begin":418,"end":422},"obj":"18653759"},{"id":"19652920-11448195-56190924","span":{"begin":584,"end":588},"obj":"11448195"},{"id":"19652920-12862493-56190925","span":{"begin":764,"end":768},"obj":"12862493"}],"attributes":[{"subj":"19652920-16939274-56190922","pred":"source","obj":"2_test"},{"subj":"19652920-18653759-56190923","pred":"source","obj":"2_test"},{"subj":"19652920-11448195-56190924","pred":"source","obj":"2_test"},{"subj":"19652920-12862493-56190925","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#93b3ec","default":true}]}]}}